Search of human proteins with 166064029

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166064029 angiomotin isoform 1 [Homo sapiens]
         (1084 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166064029 angiomotin isoform 1 [Homo sapiens]                     2141   0.0  
gi|19111150 angiomotin isoform 2 [Homo sapiens]                      1293   0.0  
gi|22027646 angiomotin like 1 [Homo sapiens]                          755   0.0  
gi|32484977 angiomotin like 2 [Homo sapiens]                          410   e-114
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             89   3e-17
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              88   4e-17
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          84   6e-16
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    82   4e-15
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         82   4e-15
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    81   5e-15
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    81   5e-15
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap...    79   2e-14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    78   4e-14
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    78   5e-14
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    78   5e-14
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    78   5e-14
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             75   3e-13
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             73   2e-12
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     72   2e-12
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                72   4e-12
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                72   4e-12
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                72   4e-12
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  72   4e-12
gi|148746195 trichohyalin [Homo sapiens]                               71   6e-12
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    70   1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    70   1e-11
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     69   3e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    69   3e-11
gi|91982772 mucin 17 [Homo sapiens]                                    69   3e-11
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              68   4e-11

>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 2141 bits (5547), Expect = 0.0
 Identities = 1084/1084 (100%), Positives = 1084/1084 (100%)

Query: 1    MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSD 60
            MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSD
Sbjct: 1    MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSD 60

Query: 61   VLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFR 120
            VLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFR
Sbjct: 61   VLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFR 120

Query: 121  GQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQ 180
            GQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQ
Sbjct: 121  GQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQ 180

Query: 181  MSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPP 240
            MSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPP
Sbjct: 181  MSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPP 240

Query: 241  EYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPL 300
            EYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPL
Sbjct: 241  EYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPL 300

Query: 301  SARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQ 360
            SARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQ
Sbjct: 301  SARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQ 360

Query: 361  AHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASY 420
            AHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASY
Sbjct: 361  AHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASY 420

Query: 421  QPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLV 480
            QPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLV
Sbjct: 421  QPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLV 480

Query: 481  KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL 540
            KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL
Sbjct: 481  KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL 540

Query: 541  FAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYV 600
            FAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYV
Sbjct: 541  FAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYV 600

Query: 601  DKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAAL 660
            DKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAAL
Sbjct: 601  DKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAAL 660

Query: 661  MELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYD 720
            MELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYD
Sbjct: 661  MELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYD 720

Query: 721  TALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLS 780
            TALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLS
Sbjct: 721  TALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLS 780

Query: 781  CMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPST 840
            CMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPST
Sbjct: 781  CMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPST 840

Query: 841  PSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA 900
            PSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
Sbjct: 841  PSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA 900

Query: 901  ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA 960
            ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
Sbjct: 901  ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA 960

Query: 961  PSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTP 1020
            PSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTP
Sbjct: 961  PSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTP 1020

Query: 1021 AVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMV 1080
            AVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMV
Sbjct: 1021 AVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMV 1080

Query: 1081 EYLI 1084
            EYLI
Sbjct: 1081 EYLI 1084


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 1293 bits (3347), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 410  MPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEI 469
            MPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEI
Sbjct: 1    MPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEI 60

Query: 470  QRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEG 529
            QRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEG
Sbjct: 61   QRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEG 120

Query: 530  SEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKL 589
            SEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKL
Sbjct: 121  SEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKL 180

Query: 590  EEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQP 649
            EEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQP
Sbjct: 181  EEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQP 240

Query: 650  TNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTT 709
            TNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTT
Sbjct: 241  TNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTT 300

Query: 710  VISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS 769
            VISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS
Sbjct: 301  VISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS 360

Query: 770  RKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLG 829
            RKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLG
Sbjct: 361  RKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLG 420

Query: 830  GDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAA 889
            GDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAA
Sbjct: 421  GDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAA 480

Query: 890  AATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPA 949
            AATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPA
Sbjct: 481  AATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPA 540

Query: 950  AASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPA 1009
            AASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPA
Sbjct: 541  AASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPA 600

Query: 1010 VAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQ 1069
            VAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQ
Sbjct: 601  VAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQ 660

Query: 1070 ILGQEPDAEMVEYLI 1084
            ILGQEPDAEMVEYLI
Sbjct: 661  ILGQEPDAEMVEYLI 675


>gi|22027646 angiomotin like 1 [Homo sapiens]
          Length = 956

 Score =  755 bits (1950), Expect = 0.0
 Identities = 450/888 (50%), Positives = 577/888 (64%), Gaps = 107/888 (12%)

Query: 1   MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGN-GPPFPSGSGNPGPQS 59
           MR SE+  +G  TVLQRL+QEQLRYG P+EN +LLAI  QATG+ GP  P+   N    +
Sbjct: 87  MRGSEDAAAG--TVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPT---NNFSST 141

Query: 60  DVLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQL--SPRMQNNEELPTYEEAKVQSQ 117
           + L+ +D   Q+V  +ARQEPQGQE Q +N +MEKQ+  +   QNNEELPTYEEAK QSQ
Sbjct: 142 ENLTQED--PQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQ 199

Query: 118 YFRGQQH-----ASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVR 172
           +FRGQQ       +VG  +Y+ G T+QK RTEGRP+V R N G+ H+DE L++LKQGHVR
Sbjct: 200 FFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVR 259

Query: 173 SLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKG 232
           SLSER+MQ+SL  +G K H P +                 +   F    GP P Q + K 
Sbjct: 260 SLSERIMQLSLERNGAKQHLPGSG----------------NGKGFKVGGGPSPAQPAGKV 303

Query: 233 MEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARP 292
           ++ RGPPPEYPFK     S V K Q       EH L    +  G L     P  Y A +P
Sbjct: 304 LDPRGPPPEYPFKTKQMMSPVSKTQ-------EHGLFYGDQHPGMLHEMVKP--YPAPQP 354

Query: 293 AQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRP 352
              +   ++    QP  P   +TS                P + P       HS   P  
Sbjct: 355 ---VRTDVAVLRYQP-PPEYGVTS---------------RPCQLPFPSTMQQHS---PMS 392

Query: 353 QQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPR 412
            Q      +  G  + +S P                              P       P+
Sbjct: 393 SQ----TSSASGPLHSVSLP-----------------------------LPLPMALGAPQ 419

Query: 413 AQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRV 472
             P+++  Q +  D FAIV RAQQMVEIL++ENR L QEL+G Y+   +L K E E+QR+
Sbjct: 420 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI 479

Query: 473 SEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSED 532
           SEAYE+LVKS++KRE+L+KAMRNKLEGEIRR+HDFNRDLR+RLETAN+QL+ +EYEG ED
Sbjct: 480 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED 539

Query: 533 TRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEE 592
            +       ++NKE  +EKEKLE ELA  R+ +ED RRHIEI DQALSNAQA+V+KLEEE
Sbjct: 540 -KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEE 598

Query: 593 LKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNV 652
           L++KQ YV+KVEK+QQAL QLQ+ACEKREQ+E RLRT LEREL++LR QQ+ GN QP N+
Sbjct: 599 LREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANM 658

Query: 653 SEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVIS 712
            EYNA AL+EL+REKEERILALEADMTKWEQKYLEE+ +RHFA++AAAT AA+RDTT+I+
Sbjct: 659 PEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIIN 718

Query: 713 HSPNTSY-DTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRK 771
           HS N SY +++LEA I +EEEE++ AN+RC DME  IK LHA+IIEKDAMIKVLQQRSRK
Sbjct: 719 HSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRK 778

Query: 772 EPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGD 831
           +  KT+  S +RPA+S+ SI+ A +G  S  ++LT S + EEK+++K+WKGS+G+LLG +
Sbjct: 779 DAGKTDS-SSLRPARSVPSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE 836

Query: 832 YR----AEYVPSTP----SPVPPSTPLLSAHSKTGSRDCSTQTERGTE 871
           +     A  +P  P    S +  +T   SAH+KTGS+D STQT++  E
Sbjct: 837 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAE 884


>gi|32484977 angiomotin like 2 [Homo sapiens]
          Length = 780

 Score =  410 bits (1053), Expect = e-114
 Identities = 266/616 (43%), Positives = 355/616 (57%), Gaps = 54/616 (8%)

Query: 287 YGAARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLL----QSPP---------STRLSP 333
           +G  R   +  L LS   +   +P S ++S  S P L    Q PP          +R  P
Sbjct: 152 HGHVRSLSERLLQLSLERNGARAP-SHMSSSHSFPQLARNQQGPPLRGPPAEGPESRGPP 210

Query: 334 ARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQ 393
            ++P V    + +  +  P+     +   Q    R+ Q  +     QQQQQ+ +    QQ
Sbjct: 211 PQYPHVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYL---QQ 267

Query: 394 QQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEI---------LSDE 444
            Q+  P   P         +    A   PV A   +  S +  + ++         L  +
Sbjct: 268 SQEHPPPPHPAALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRD 327

Query: 445 NRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRM 504
           N  L++ELE   EK  R++K+E+EIQR+SEA+E+L ++SSKREALEK MRNK++ E+RR+
Sbjct: 328 NERLQRELESSAEKAGRIEKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRL 387

Query: 505 HDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARST 564
            DFNRDLRERLE+AN++LA K  E    ++  +++L A++ E Q+E+EKLE E+A  R  
Sbjct: 388 QDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLAQSYEQQQEQEKLEREMALLRGA 447

Query: 565 NEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLE 624
            EDQRR  E+ +QAL NAQ +  + EEEL+KKQ YV+KVE++QQAL QLQAACEKREQLE
Sbjct: 448 IEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAACEKREQLE 507

Query: 625 HRLRTRLERELESLRIQQRQ-----GNCQPTNVSEYNAAALMELLREKEERILALEADMT 679
            RLRTRLE+EL++LR QQRQ     G+       E +A  L E LREKEE+ILALEADMT
Sbjct: 508 LRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALEADMT 567

Query: 680 KWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANK 739
           KWEQKYLEE  MR FA+DAAAT AAQRDTT+I HSP  S  ++         E +L    
Sbjct: 568 KWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSF-------NEGLLTGGH 620

Query: 740 RCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLL 799
           R  +ME R+K LHAQI+EKDA+IKVLQQRSR++P K  Q S +RPAKS+ S+  A +   
Sbjct: 621 RHQEMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGS-LRPAKSVPSVFAAAAAGT 679

Query: 800 SHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGS 859
                L+ S   E +  D               R       P+  P  T   +AH+K GS
Sbjct: 680 QGWQGLSSS---ERQTAD------------APARLTTADRAPTEEPVVTAPPAAHAKHGS 724

Query: 860 RDCSTQTERGTESNKT 875
           RD STQTE   +S  T
Sbjct: 725 RDGSTQTEGPPDSTST 740


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 77/233 (33%), Positives = 115/233 (49%), Gaps = 19/233 (8%)

Query: 834  AEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATA 893
            A   P   +P+PPST   S  + T +   +T T        T+A  P S  APV A+ +A
Sbjct: 1744 ASVPPLASAPLPPSTSA-SVPASTSAPLPATLTPVPAS---TSAPVPASTLAPVLASTSA 1799

Query: 894  -------AAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAA-ATAAAVSPAAAG 945
                   A ++A+A+   +   + +  A+ +++APA+A AP+P  A+ +T A+V+  A+ 
Sbjct: 1800 PVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASA 1859

Query: 946  QIPAAASV---ASAAAVAPSAAA-AAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
             IP  AS     SA   AP+A++ AA V  AP  PA  P  ++   PA A+A A AP   
Sbjct: 1860 SIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPV 1919

Query: 1002 QAPTSA-PAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTD 1053
             AP  A PA A T A T  P     +  +  +  P P  + +PS    P+ TD
Sbjct: 1920 SAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQP-PPSIRLPSAQ-TPNGTD 1970



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 97/316 (30%), Positives = 142/316 (44%), Gaps = 56/316 (17%)

Query: 724  EARIQKEEEEILMANKRCLDMEGRIKT--LHAQIIEKDAMIKVLQQRSRKEPSKTEQLSC 781
            E R +KEE+ I + NK+  + +GR +T  L  +  +K A      Q+++   S     S 
Sbjct: 1696 EERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQA---TGIQQAQSSASVPPLASA 1752

Query: 782  MRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTP 841
              P  +  S+  + S  L   +TLT  P             S    +     A  + ST 
Sbjct: 1753 PLPPSTSASVPASTSAPLP--ATLTPVP------------ASTSAPVPASTLAPVLASTS 1798

Query: 842  SPVP--PSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITAT 899
            +PVP  P  P+ ++ S + S   ST     T S+     AP S PAP    A+     +T
Sbjct: 1799 APVPASPLAPVSASASVSASVPASTSAAAITSSS-----APASAPAPTPILAS----VST 1849

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV 959
             A++T    A+ P+    A+A A+ +AP+PA AA++ AA     A  IPA+A  AS   +
Sbjct: 1850 PASVTILASASIPI---LASALASTSAPTPAPAASSPAA-PVITAPTIPASAPTAS-VPL 1904

Query: 960  APSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAP------- 1012
            AP++A         +APAP P P   P PAP      APAQTQA T  P   P       
Sbjct: 1905 APASA---------SAPAPAPTPVSAPNPAP-----PAPAQTQAQTHKPVQNPLQTTSQS 1950

Query: 1013 TPAPTPTPAVAQAEVP 1028
            +  P P+  +  A+ P
Sbjct: 1951 SKQPPPSIRLPSAQTP 1966



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 71/211 (33%), Positives = 101/211 (47%), Gaps = 30/211 (14%)

Query: 852  SAHSKTGSRDCSTQTERGTESNKTAAVAPI-SVPAPVAAAATAAAITATAATITTTMVAA 910
            S  SK   R    Q     ++  +A+V P+ S P P + +A+  A T+     T T V A
Sbjct: 1720 SQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPA 1779

Query: 911  ---APV-------AVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA 960
               APV        +A+ +AP  A+  +P +A+A+ +A  PA+       +S A A+A A
Sbjct: 1780 STSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPA 1839

Query: 961  P-----SAAAAAAVQVAPAAPAPVPAPAL----VPVPAPAAAQASAPAQT------QAPT 1005
            P     S +  A+V +  +A  P+ A AL     P PAPAA+  +AP  T       APT
Sbjct: 1840 PTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPT 1899

Query: 1006 S----APAVAPTPAPTPTPAVAQAEVPASPA 1032
            +    APA A  PAP PTP  A    P +PA
Sbjct: 1900 ASVPLAPASASAPAPAPTPVSAPNPAPPAPA 1930



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 88/449 (19%), Positives = 164/449 (36%), Gaps = 71/449 (15%)

Query: 231 KGMEHRGPPPEYPFKGMPPQSVVCKP-QEPGHFYSEHRLNQPGRTEGQL-------MRYQ 282
           KG+  RGPPP +  +   P  +     +E   F +       G    Q+       + + 
Sbjct: 276 KGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFS 335

Query: 283 HPPEYGAARPAQDISLPLSAR---NSQPHSPTSSLTSGGSLPLLQSPPSTRLSP-ARHPL 338
              E G+  P ++ S    ++   N++    T  +++  S   + + PS    P  + P 
Sbjct: 336 DDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395

Query: 339 VPNQGDHSAHLPRP-----QQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQ 393
              +   S+HLP P     QQH  P+        R + PG       +QQ        +Q
Sbjct: 396 FNQERGTSSHLPPPPKLLAQQHPPPD--------RQAVPGRPGPFPSKQQVADEDEIWKQ 447

Query: 394 QQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELE 453
           +++QQ +                            A V RA++  E   +E R   Q   
Sbjct: 448 RRRQQSEIS--------------------------AAVERARKRRE--EEERRMEEQRKA 479

Query: 454 GCYEKVARLQKV--------------ETEIQRVSEAYENLVKSSSKREALEKAMRNKLEG 499
            C EK+ RL +               E E ++  E  + L K   +    E+    + + 
Sbjct: 480 ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ 539

Query: 500 EIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQ--REKEKLEAE 557
           E  +  +  ++ +  +E   KQ  EKE E  ++  K + ++  + KE +  +E+EKLE +
Sbjct: 540 EKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599

Query: 558 LATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQV--YVDKVEKMQQALVQLQA 615
           +       E      E  +      +    + +    +K+    V + E    +  +   
Sbjct: 600 IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAV 659

Query: 616 ACEKREQLEHRLRTRLERELESLRIQQRQ 644
                +Q +  L  R +R+ E ++ QQ Q
Sbjct: 660 LSGYFKQFQKSLPPRFQRQQEQMKQQQWQ 688



 Score = 37.4 bits (85), Expect = 0.077
 Identities = 53/219 (24%), Positives = 95/219 (43%), Gaps = 46/219 (21%)

Query: 474 EAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDL-RERLETANKQLAEKEYEGSED 532
           E ++   +  S+  A  +  R + E E RRM +  +    E+L+  +++L   E + S +
Sbjct: 443 EIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502

Query: 533 TRKTISQLFAKNKESQREKEK-LEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEE 591
                 ++  + +E +RE+EK LE E        ++Q R  E R++     Q K    E+
Sbjct: 503 ------EIREREREKEREREKELEKE--------QEQEREKE-REKDRERQQEK----EK 543

Query: 592 ELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTN 651
           EL+K+Q                    EK+ ++E   +   E+ELE     Q++   +   
Sbjct: 544 ELEKEQ--------------------EKQREMEKERKQEKEKELER----QKEKEKELQK 579

Query: 652 VSEYNAAALMELLREK-EERILALEADMTKWEQKYLEEN 689
           + E      +E  REK EE+I   E ++    +K   EN
Sbjct: 580 MKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESEN 618



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 1/86 (1%)

Query: 348 HLPRPQQHFLPNQAHQGDHYRLSQPGLSQQ-QQQQQQQHHHHHHHQQQQQQQPQQQPGEA 406
           H   P+    P  A    +++  Q  L  + Q+QQ+Q        QQQQ   PQ  P + 
Sbjct: 645 HETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQP 704

Query: 407 YSAMPRAQPSSASYQPVPADPFAIVS 432
            S+     P    YQP+   P  + S
Sbjct: 705 SSSTVPPPPHRPLYQPMQPHPQHLAS 730



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 82/390 (21%), Positives = 131/390 (33%), Gaps = 61/390 (15%)

Query: 67   HHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHAS 126
            H  QL   A     Q QE+ S +L   +     MQ++   P+   +      F   QH  
Sbjct: 2441 HQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQE 2500

Query: 127  VGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATS 186
            +  A   +G+  Q+  T     +  L   ++ Q  GL     G  + +   L+Q   A +
Sbjct: 2501 LAKA--QSGLAFQQ--TSNTQPIPILYEHQLGQASGL-----GGSQLIDTHLLQ---ARA 2548

Query: 187  GVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLP-NQHSLKGMEHRGPPP----- 240
             +     + S  +  P   + Y    S S   +   PLP +Q SL      G P      
Sbjct: 2549 NLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQ 2608

Query: 241  --EYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQL------MRYQHPPEYG---- 288
              + P +   PQ+       P       R   P  T+  +      M       +G    
Sbjct: 2609 TLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGID 2668

Query: 289  --------AARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPST-RLSPARHPLV 339
                    A R     S P  A ++ P+S +S + S       QS P+T R++       
Sbjct: 2669 IKPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQ------ 2722

Query: 340  PNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQP 399
                      P P Q F P    + +  + +Q   S+QQQ +Q         + Q+    
Sbjct: 2723 ----------PFPTQ-FAPQAKQRAEVLQSTQRFFSEQQQSKQ-----IGGGKAQKVDSD 2766

Query: 400  QQQPGEAYSAMPRAQPSSASYQPVPADPFA 429
              +P E  +  P         +P PA   A
Sbjct: 2767 SSKPPETLTDPPGVCQEKVEEKPPPAPSIA 2796



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 14/142 (9%)

Query: 311  TSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAH--QGDHYR 368
            TSSL S      L   PS      ++P V      +A +P     F  + +H     H R
Sbjct: 2349 TSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPA----FYMDTSHLFNTQHAR 2404

Query: 369  LSQPGLSQQQQQQQ--------QQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASY 420
            L+ P L+QQQ  Q         QQ     +   Q Q Q Q   G   +     +  S+S 
Sbjct: 2405 LAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSL 2464

Query: 421  QPVPADPFAIVSRAQQMVEILS 442
            QP  + P  + S   Q   +LS
Sbjct: 2465 QPYRSQPAFMQSSLSQPSVVLS 2486


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 74/250 (29%), Positives = 111/250 (44%), Gaps = 35/250 (14%)

Query: 792  SNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLL 851
            SN  S      + +TG+  M++  ++   + S  I        E+ P   S    +TPLL
Sbjct: 268  SNLQSRSFRILAQMTGTEFMQDPDEEALRRSSTPI--------EHAPVCTSQA--TTPLL 317

Query: 852  SAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAA 911
             A ++                   AA +P +   P+A AA   AI + + T   +  A +
Sbjct: 318  PASAQP-----------------PAAASPSAASPPLATAAAHTAIASASTTAPASSPADS 360

Query: 912  PVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQV 971
            P   A++ +PA AA+ +PAT   T+ +  PAA    P   + AS          A+    
Sbjct: 361  PRPQASSYSPAVAASSAPATH--TSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSP 418

Query: 972  APAA---PAP-VPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAP--TPTPAVAQA 1025
            +P A   P P  P+PA    P+PA A   +P  T  P+ APA  P+PAP   P P+VA +
Sbjct: 419  SPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYS 478

Query: 1026 EVPASPATGP 1035
              PA PA+ P
Sbjct: 479  GGPAEPASRP 488



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 56/170 (32%), Positives = 80/170 (47%), Gaps = 13/170 (7%)

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            S P   A   T+ A T           AA+P A +   A AAA   + A+A+ TA A SP
Sbjct: 299  STPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHT-AIASASTTAPASSP 357

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
            A + + P A+S + A A + + A   +    PAAPAP P      V   A+ + S     
Sbjct: 358  ADSPR-PQASSYSPAVAASSAPATHTSYSEGPAAPAPKPR-----VVTTASIRPSVYQPV 411

Query: 1002 QAPTSAPAVAPTPAPTP-TPAVAQAEVPA-SPATGPGPHRLSIPSLTCNP 1049
             A T +P+     +PTP TP+ A A  P+ +PA  P P    +P+ T +P
Sbjct: 412  PASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSP----VPTYTPSP 457



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 48/165 (29%), Positives = 72/165 (43%), Gaps = 20/165 (12%)

Query: 904  TTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSA 963
            ++T +  APV  + A  P   A+  P  AA+ +AA  P A     A  ++ASA+  AP++
Sbjct: 298  SSTPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAA--AHTAIASASTTAPAS 355

Query: 964  AAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVA-----------P 1012
            + A + +  P A +  PA A    PA   + +  PA   AP   P V            P
Sbjct: 356  SPADSPR--PQASSYSPAVAASSAPATHTSYSEGPA---APAPKPRVVTTASIRPSVYQP 410

Query: 1013 TPAPT--PTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGP 1055
             PA T  P+P    +  P +P+  P       P+ T +P  T  P
Sbjct: 411  VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTP 455


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 103/320 (32%), Positives = 129/320 (40%), Gaps = 85/320 (26%)

Query: 767  QRSRKEPSKTEQLSCMRPAKSL---MSISNA---------GSGLLSHSSTLTGSPIMEEK 814
            Q+S  +P   +  +C+RP        ++S A         G G +SHSS+   S      
Sbjct: 378  QKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLS- 436

Query: 815  RDDKSWKGSLGILLGGDYRAEYVPSTPSPV--------------PPSTPLLSAHSKTGSR 860
                SWK                P  P PV              PP T L S+  K  S 
Sbjct: 437  ----SWK---------------TPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSG 477

Query: 861  DCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAA 920
            +     + G+   +  + A  ++ A  AAAA AAA  A AA       AAAP A+AAAAA
Sbjct: 478  NSFPPQQAGSPLKRPFSAAA-AIAAAAAAAAAAAAAAAAAAPAPALAAAAAP-ALAAAAA 535

Query: 921  P--AAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978
            P  AAAAAP+PA AAA A A +PA      AAAS A + +  PS     A +  PAA  P
Sbjct: 536  PALAAAAAPAPAPAAAPAVAAAPA------AAASAAPSHSQKPSVPLIQASRPCPAAQPP 589

Query: 979  VP----APAL-----------VPVPAP---AAAQASAPAQTQAPTS-APAVAPT------ 1013
                  APA+           + V  P   A A  S+    QAP S APA A        
Sbjct: 590  TKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQ 649

Query: 1014 ----PAPTPTPAVAQAEVPA 1029
                P P   P   QA  PA
Sbjct: 650  SSGGPLPDARPGAVQASSPA 669



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 58/155 (37%), Positives = 75/155 (48%), Gaps = 13/155 (8%)

Query: 926  APSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALV 985
            A SP     +AAA   AAA    AAA+ A+AAA AP+ AAAAA  +A AA     APAL 
Sbjct: 485  AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAA-----APALA 539

Query: 986  PVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSL 1045
               APA A A+APA   AP +A + AP+ +  P+  + QA  P   A  P       P++
Sbjct: 540  AAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAI 599

Query: 1046 TCNPDKT-------DGPVFHSNTLERK-TPIQILG 1072
                  T       +GPV  +  L     P+Q  G
Sbjct: 600  QLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPG 634



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 65/218 (29%), Positives = 92/218 (42%), Gaps = 17/218 (7%)

Query: 827  LLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAP 886
            LL G  R        S   P  P    HS        T   R     + +  + +  P  
Sbjct: 362  LLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGK 421

Query: 887  VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAA--------- 937
            ++ +++  A  +  ++  T      PV V ++ +      P P T   +++         
Sbjct: 422  MSHSSSGPASVSQLSSWKTPE-QPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480

Query: 938  ----AVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993
                A SP       AAA  A+AAA A +AAAAAA   APA  A   APAL    APA A
Sbjct: 481  PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPAL-AAAAAPALAAAAAPALA 539

Query: 994  QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
             A+APA   AP +APAVA  PA   + A + ++ P+ P
Sbjct: 540  AAAAPA--PAPAAAPAVAAAPAAAASAAPSHSQKPSVP 575



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 66/255 (25%), Positives = 90/255 (35%), Gaps = 52/255 (20%)

Query: 193 PVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMP---- 248
           PV +     P P  +     S S+   + GPLP+      ++   P P   F   P    
Sbjct: 629 PVQAPGSGAPAPAGI-----SGSDLQSSGGPLPDARP-GAVQASSPAPLQFFLNTPEGLR 682

Query: 249 -------PQ--SVVCKPQEPGH-FYSEHRLNQPGRTEGQLMRYQHPPE------------ 286
                  PQ  +V+  PQ+  H   S  +L QP           HPP+            
Sbjct: 683 PLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAA--------HPPQPGPQGSALGLST 734

Query: 287 YGAARPAQDISL--PLSARNS-QPHSPTSSLTSGGSLPLLQSP---PSTRLSPARHPLVP 340
            G A PAQ +    P  AR+  QP    + L+  GS  + Q     PS        P  P
Sbjct: 735 QGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQLPSVLRQQQPQPQPP 794

Query: 341 NQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQ 400
                    P+P+Q    +Q  Q  H +L      Q QQ +  Q   H   Q QQ +  Q
Sbjct: 795 KLQLQPQWQPKPRQEQPQSQQQQPQHIQL------QTQQLRVLQQPQHIQLQTQQLRVLQ 848

Query: 401 QQPGEAYSAMPRAQP 415
           Q    A  A+   QP
Sbjct: 849 QPVFLATGAVQIVQP 863


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sapiens]
          Length = 288

 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 80/240 (33%), Positives = 103/240 (42%), Gaps = 49/240 (20%)

Query: 853  AHSKTGSRDCSTQTE----RGTESNKTAAV-------APISVP-------------APVA 888
            +H     + C T+T+    RG     T  +       AP+ VP             AP A
Sbjct: 45   SHDTQRLKSCDTETKERKTRGDSCGNTRNLYPLTPWSAPVVVPSALTRAVAWRPAAAPAA 104

Query: 889  ---------AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAV 939
                     AAA AA   A A     ++ AA+P A   AA PAA   P+    AA  AAV
Sbjct: 105  VRPPAAGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPAAALAAV 164

Query: 940  SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP----VPAPALVPVPAPAAAQA 995
             PAAA   P+AAS+ +A+ +A   AAA+   VAPAA  P      A +L     PAA  A
Sbjct: 165  YPAAAD--PSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPA 222

Query: 996  SAPAQTQAPTSA-PAVAPTPAPTPTPAVAQ--AEVPASP-------ATGPGPHRLSIPSL 1045
            +A     AP +  PA A   A  P  A  Q  AE PA+P       +  P P   ++P L
Sbjct: 223  AASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAIAQPVSFPPAPVPCAVPPL 282



 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 60/152 (39%), Positives = 73/152 (48%), Gaps = 6/152 (3%)

Query: 876  AAVAPISVPAPVAAAATAAAITATAATITTTMVAAA-PVAVAAAAAPAAAAAPSPATAAA 934
            AA  P +VPA V AA    A    AA +     AAA P A +  AA   AA P+ A+ AA
Sbjct: 134  AASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAA 193

Query: 935  TA-AAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993
             A AAV P AAG  P+AAS+ +A+  A   AAA+    AP A  P  A      PA A  
Sbjct: 194  VAPAAVCPGAAG--PSAASLCAASQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACV 251

Query: 994  Q--ASAPAQTQAPTSAPAVAPTPAPTPTPAVA 1023
            Q  A +PA   A     +  P P P   P +A
Sbjct: 252  QSVAESPATPLAIAQPVSFPPAPVPCAVPPLA 283



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 66/182 (36%), Positives = 84/182 (46%), Gaps = 25/182 (13%)

Query: 877  AVAPISVPAPVA---AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAA 933
            A AP +V  P A   AAA AA   A A     ++ AA+P A   AA PAA   P+    A
Sbjct: 99   AAAPAAVRPPAAGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPA 158

Query: 934  ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993
            A  AAV PAAA   P+AAS+ +A+ +A   AAA+   VAPAA  P  A        P+AA
Sbjct: 159  AALAAVYPAAAD--PSAASLCAASPLAAVPAAASPAAVAPAAVCPGAA-------GPSAA 209

Query: 994  QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTD 1053
               A +Q       PA  P  A +P  A   A  PA+ A        + P+  C     +
Sbjct: 210  SLCAASQ-------PAAVPA-AASPAAAAPLAVNPAAAA-----RAAAAPAAACVQSVAE 256

Query: 1054 GP 1055
             P
Sbjct: 257  SP 258



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 55/181 (30%), Positives = 74/181 (40%), Gaps = 28/181 (15%)

Query: 841 PSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAAT-------- 892
           P    P+    +A   + +  C+        +   AAV P +   P AA A         
Sbjct: 112 PPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAADP 171

Query: 893 AAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPAT----------------AAATA 936
           +AA    A+ +     AA+P AVA AA    AA PS A+                AAA  
Sbjct: 172 SAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAAASPAAAAP 231

Query: 937 AAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQAS 996
            AV+PAAA +  AA + A   +VA S A   A+   P +  P P P  VP   P AA+  
Sbjct: 232 LAVNPAAAARAAAAPAAACVQSVAESPATPLAI-AQPVSFPPAPVPCAVP---PLAAELL 287

Query: 997 A 997
           A
Sbjct: 288 A 288



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 12/107 (11%)

Query: 839 STPSPVPPSTPLLSAHSKTGSRDCS-TQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
           ++P+ V P+     A   + +  C+ +Q      +   AA AP++V  P AAA  AAA  
Sbjct: 189 ASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAAASPAAAAPLAVN-PAAAARAAAA-- 245

Query: 898 ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 944
              A      VA +P      A P A A P     A    AV P AA
Sbjct: 246 --PAAACVQSVAESP------ATPLAIAQPVSFPPAPVPCAVPPLAA 284


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 89/315 (28%), Positives = 129/315 (40%), Gaps = 74/315 (23%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTA-AVAPISVP--APVAAAATAAA 895
            S+P P+P S+PL S  S T S   S+       +   A A AP+++P  AP+  +A+  A
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471

Query: 896  ITATAATITTTMVAAAPVAVAAA---AAPAAAA-----------------------APSP 929
            +  +       +V AAP   + A   A+P+A+A                       AP+ 
Sbjct: 1472 LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS 1531

Query: 930  ATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPA------------ 977
            +      + V+PA +  +  A+++AS    AP+ A A A  +APA+ A            
Sbjct: 1532 SHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMA 1591

Query: 978  --------PVPAPALVPVP--------APAAAQASAPAQTQAPTSAP-----AVAPTPAP 1016
                    P PAP L P+P        AP  A +  P    AP+S P     + +P PAP
Sbjct: 1592 APQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP 1651

Query: 1017 TP--TPAVAQAEVPASPATGPGPHRLSIPSLTCNP--DKTDGPVFHSNTLERKT------ 1066
            TP   P+  Q  +PA P   P P   S  +L   P    T G    S TL   T      
Sbjct: 1652 TPVLAPSSTQTMLPA-PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710

Query: 1067 -PIQILGQEPDAEMV 1080
             P Q L   P + +V
Sbjct: 1711 FPTQTLSLTPASSLV 1725



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 65/222 (29%), Positives = 89/222 (40%), Gaps = 30/222 (13%)

Query: 841  PSPVPPSTPLLSAHSKTGSRD--CSTQTE------RGTESNKTAAVAPISVPAPVAA-AA 891
            PSP PP  PL       G+     S+QT         T     A+ +P+  P PV A ++
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSS 1659

Query: 892  TAAAITATAATITTTMVAAAPVAVAAAAAPA-AAAAPSPATAAATAAAVSP--------- 941
            T   + A   +   +  +   +A+A A AP    ++PS   +  T     P         
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT 1719

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
             A+  +P  A   S A   P        Q    APAP  APA    PAPA     APA +
Sbjct: 1720 PASSLVPTPAQTLSLAPGPP----LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASS 1775

Query: 1002 QAPTSAPA------VAPTPAPTPTPAVAQAEVPASPATGPGP 1037
             A   APA      ++P P PT  PA AQ  +  +PA+   P
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQT-LALAPASTQSP 1816



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 66/253 (26%), Positives = 100/253 (39%), Gaps = 23/253 (9%)

Query: 826  ILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPIS--V 883
            +L+     A   PS P+P P    LL+  S       +             A +P     
Sbjct: 1548 VLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLA 1607

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P PV A +  AA    ++     ++A +     + A+ +   AP+P  A ++   + PA 
Sbjct: 1608 PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAP 1667

Query: 944  A-GQIPAAAS---VASAAAVAPSAAAAAAVQVA------PAAPAPV------PAPALVPV 987
                +P+ AS   +A A A+AP+   ++  Q        P  P P       PA +LVP 
Sbjct: 1668 VPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT 1727

Query: 988  PAPAAAQASAP----AQTQAPTSAPAVAPTPAPTPTPAVAQAEVPA-SPATGPGPHRLSI 1042
            PA   + A  P     QT +   AP +AP     P PA      PA S A+   P  +  
Sbjct: 1728 PAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQT 1787

Query: 1043 PSLTCNPDKTDGP 1055
             +L+  P  T GP
Sbjct: 1788 LTLSPAPVPTLGP 1800



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 75/268 (27%), Positives = 103/268 (38%), Gaps = 51/268 (19%)

Query: 823  SLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPIS 882
            +LG+       +   P  P  + P++  +   + T +  CS      +        AP  
Sbjct: 1506 TLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPN- 1564

Query: 883  VPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAA-VSP 941
             PAP  A+  A A +A+ A  T     AAP     A +PA   AP P  A +  AA V  
Sbjct: 1565 -PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLA 1623

Query: 942  AAAGQIPAAA-------SVASAAAVAPSAAAAAAVQVAPAAPAPVPAP----------AL 984
            ++   +P  A       S+ASA+ V       A        PAPVP+P          AL
Sbjct: 1624 SSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLAL 1683

Query: 985  VPVPAPAAA---------------QASAPAQTQAPTSAPAVAPTPA------------PT 1017
             P  AP                  Q   P QT + T A ++ PTPA            PT
Sbjct: 1684 APALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPT 1743

Query: 1018 PTPAVAQAE--VPASPATGPGP-HRLSI 1042
             T ++A A    PASP  GP P H L++
Sbjct: 1744 QTLSLAPAPPLAPASP-VGPAPAHTLTL 1770



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 65/245 (26%), Positives = 92/245 (37%), Gaps = 49/245 (20%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTE-SNKTAAVAPISVPA------------ 885
            ++ SPVP  TP+L+  S          +   +  S +T A+AP   P             
Sbjct: 1643 ASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSL 1702

Query: 886  ----PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
                P     T       A+++  T      +A      P    + +PA   A A+ V P
Sbjct: 1703 GTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGP 1762

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
            A A  +  A + +SA+ +AP     A+VQ    +PAPVP       PA A   A APA T
Sbjct: 1763 APAHTLTLAPASSSASLLAP-----ASVQTLTLSPAPVPTLG----PAAAQTLALAPAST 1813

Query: 1002 QAPTS--------APAVAPTPA----------PTPTPAVAQAEVPASPAT-----GPGPH 1038
            Q+P S        A   AP P             P     ++  P+ P+T     GP P 
Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPR 1873

Query: 1039 RLSIP 1043
            R   P
Sbjct: 1874 RQPPP 1878



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 6/166 (3%)

Query: 880  PISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA-APAAAAAPSPATAAATAAA 938
            P S P P+  ++  A+    ++T++  + ++ P++V     APA+A    P +A  T +A
Sbjct: 1410 PASSPMPIPNSSPLAS--PVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSA 1467

Query: 939  VSPAAAGQI-PAAASVASAAAVAPSAAAAAAVQVAPAAPAPVP-APALVPVPAPAAAQAS 996
              PA    + P  A V  AA   PS A + A   A A    +  AP+L     P      
Sbjct: 1468 SGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLL 1527

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042
            AP  +  P     VAP  +P   PA A A  P   A  P P + S+
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALAS-PFPSAPNPAPAQASL 1572



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 59/215 (27%), Positives = 89/215 (41%), Gaps = 33/215 (15%)

Query: 837  VPSTPSPVPPST----------PLLSAHSKTGSRDCSTQTERGTESNKTAAVAPIS--VP 884
            VPS P P P ST          P L   S + +    T   +G    +T ++ P S  VP
Sbjct: 1668 VPS-PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP 1726

Query: 885  APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 944
             P    + A        T T ++  A P+A A+   PA A   + A A+++A+ ++PA+ 
Sbjct: 1727 TPAQTLSLAPG-PPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASV 1785

Query: 945  GQI-----------PAAASV---ASAAAVAP-SAAAAAAVQVAPAAPAPVPAPALVPV-- 987
              +           PAAA     A A+  +P S A++  V  + AAP PV   + +PV  
Sbjct: 1786 QTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSK 1845

Query: 988  --PAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTP 1020
              P     ++  P+     TS     P   P P P
Sbjct: 1846 DEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPP 1880



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 53/203 (26%), Positives = 81/203 (39%), Gaps = 29/203 (14%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            P  P+P PPS+ L +                    N    + P  +P P    A A   T
Sbjct: 1326 PLAPAPRPPSSGLPAV------------------LNPRPTLTPGRLPTPTLGTARAPMPT 1367

Query: 898  ATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAAATAAAVSPAAAGQIPAAASVA 954
             T       +V +    V+A+A   AP   ++P    ++    A SP     IP ++ +A
Sbjct: 1368 PTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP---IPNSSPLA 1424

Query: 955  SAAAVAPSAAAAAAVQVAPAAPAPVPAPA--LVPVPAPAAAQASAPA--QTQAPTSAPAV 1010
            S  +   S   ++++ ++     P PA A   +P+ AP    AS PA   +  P  AP V
Sbjct: 1425 SPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVV 1484

Query: 1011 APTPAPTPTPAVAQAEVPASPAT 1033
               P P P+ A + A   AS  T
Sbjct: 1485 PAAPGP-PSLAPSGASPSASALT 1506



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 76/290 (26%), Positives = 106/290 (36%), Gaps = 73/290 (25%)

Query: 784  PAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWK------GSLGILLGGDYRAEYV 837
            PA  ++S S AG  L+  S      P++       S          LG+L G        
Sbjct: 1046 PASLMVSASPAGPPLIPASRP--PGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSR----- 1098

Query: 838  PSTPS----PVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPA----PVAA 889
            P TP+    P PP+   LS     GS               ++ + P++VP     P AA
Sbjct: 1099 PPTPTLSLKPTPPAPVRLSPAPPPGS---------------SSLLKPLTVPPGYTFPPAA 1143

Query: 890  AATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPA----AAG 945
            A T +  TATA T                A PA   AP     +    A  P+    + G
Sbjct: 1144 ATTTSTTTATATT---------------TAVPAPTPAPQRLILSPDMQARLPSGEVVSIG 1188

Query: 946  QIPAAAS--VASAAAVAP----------SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993
            Q+ + A   VA+A    P          +   A   Q+A   P P+    +  V A    
Sbjct: 1189 QLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSA--GG 1246

Query: 994  QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIP 1043
            Q    +Q        AVAPTP PTP   +  +    +P+T P P  LS+P
Sbjct: 1247 QHHLISQPAHVALIQAVAPTPGPTPVSVLPSS----TPSTTPAPTGLSLP 1292



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/221 (25%), Positives = 73/221 (33%), Gaps = 38/221 (17%)

Query: 861  DCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVA--AAPVAVAAA 918
            + S  T  GT      A AP      V+     A      A  T  + A           
Sbjct: 2369 ESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPR 2428

Query: 919  AAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978
             +PA    P PA       A +PAA   IPA   V  +A V  SA     +      P+P
Sbjct: 2429 CSPARERVPRPAPRPRPTPASAPAA---IPALVPVPVSAPVPISAPNPITILPVHILPSP 2485

Query: 979  VPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPH 1038
             P P+ +P                 P S+PA  P PA TP PA           T   P 
Sbjct: 2486 -PPPSQIP-----------------PCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPL 2527

Query: 1039 RLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEM 1079
             L  PS+  +   T+ P               LG  P+AE+
Sbjct: 2528 LLGPPSVPISASVTNLP---------------LGLRPEAEL 2553



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 13/173 (7%)

Query: 830  GDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAP--- 886
            G +  + +  TP+     TP  +     G     TQT     +   A  +P+  PAP   
Sbjct: 1709 GPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVG-PAPAHT 1767

Query: 887  --VAAAATAAAITATAATITTTMVAA-APVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
              +A A+++A++ A A+  T T+  A  P    AAA   A A  S  + A+ A+++  +A
Sbjct: 1768 LTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSA 1827

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPV------PAPALVPVPAP 990
            +G  P   ++ S   V+        ++  P +P         P P   P P P
Sbjct: 1828 SGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPP 1880



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 36/157 (22%), Positives = 59/157 (37%), Gaps = 11/157 (7%)

Query: 872  SNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPAT 931
            +N  A + P+ V  P     +A     T   +   + A+  V+ + A  P   A+  P  
Sbjct: 1013 NNPRAPLGPVPVRPPPGPELSAQP---TPGPVPQVLPASLMVSASPAGPPLIPASRPPGP 1069

Query: 932  AAATAAAVSPAAAGQI-PAAASVASAAAVAPSAAAA------AAVQVAPAAPAPVPAPAL 984
                    +  +  Q+ P+   V S  +  P+   +      A V+++PA P P  +  L
Sbjct: 1070 VLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPP-PGSSSLL 1128

Query: 985  VPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
             P+  P        A T   T+      T  P PTPA
Sbjct: 1129 KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPA 1165



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 52/224 (23%), Positives = 89/224 (39%), Gaps = 26/224 (11%)

Query: 838  PSTPSPV-PPSTPLLSAHSKT--GSR---DCSTQTERGTESNKTAAVAP-----ISVPAP 886
            PS+P  + PPS P+ ++ +    G R   +   Q     ES + A+VA      +S+  P
Sbjct: 2523 PSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPP 2582

Query: 887  VAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQ 946
                  A  I   +    +   +A  + + A + P      +P +A  T   V P    +
Sbjct: 2583 KDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGE-E 2641

Query: 947  IPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVP--APALVPVPAP------AAAQASAP 998
            +P   S ++   + PSAA+   +Q    A         A  P  +P        A+ +AP
Sbjct: 2642 LPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAP 2701

Query: 999  AQTQAPTSAPAVAPTPAPTPTPAVA-----QAEVPASPATGPGP 1037
            + + + TS+P   P+PA  P    +     + +    P   PGP
Sbjct: 2702 STSSSATSSPE-GPSPARPPRRRTSADVEIRGQGTGRPGQPPGP 2744



 Score = 38.1 bits (87), Expect = 0.045
 Identities = 39/207 (18%), Positives = 70/207 (33%), Gaps = 7/207 (3%)

Query: 840  TPSP-----VPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
            TP P     V PS+PLL            T    G           ++ P  +  A+ A+
Sbjct: 2512 TPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVAS 2571

Query: 895  AITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVA 954
            + T++ + +    +    V +   +    +  PS  +    A ++      + P +A   
Sbjct: 2572 SETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGT 2631

Query: 955  SAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA--PTSAPAVAP 1012
            +   +         V  +     P  A +  P+  P  A  ++   T+A  PTS+P    
Sbjct: 2632 TLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQ 2691

Query: 1013 TPAPTPTPAVAQAEVPASPATGPGPHR 1039
                    A + +    S   GP P R
Sbjct: 2692 ELVTAEVAAPSTSSSATSSPEGPSPAR 2718



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 57/284 (20%), Positives = 95/284 (33%), Gaps = 21/284 (7%)

Query: 763  KVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKG 822
            KVL++   +  +  E+   +R  +     ++     +S +S   GSP +      +S   
Sbjct: 2745 KVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPP 2804

Query: 823  SLGILLGGDYRAEYVPSTPSPVPPSTPLLS-AHSKTGSRDCSTQTERGTESNKTAAVAPI 881
                 +GG    E  PS+  P PP  P ++  H + G       T  G+  N   A+  I
Sbjct: 2805 -----IGGP--CEAAPSSSLPTPPQQPFIARRHIELG------VTGGGSPENGDGALLAI 2851

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            + PA             + A      V  AP +        A   P P T       + P
Sbjct: 2852 TPPAVKRRRGRPPKKNRSPAD-AGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEP 2910

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
                 IP    +       P+   +   +     P P      +P    +A   ++ ++T
Sbjct: 2911 QL---IPGPQPLGPQPVHRPNPLLSPVEKRRRGRP-PKARDLPIPGTISSAGDGNSESRT 2966

Query: 1002 QAPTSAPAVAPTP--APTPTPAVAQAEVPASPATGPGPHRLSIP 1043
            Q P     + P P     PT  VA      + +T P   +   P
Sbjct: 2967 QPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRP 3010


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 99/418 (23%), Positives = 187/418 (44%), Gaps = 62/418 (14%)

Query: 441  LSDENRNLRQELEG---CYEKVARLQ----KVETEIQRVSEAYENLVKSSSKREALE--- 490
            L +EN  LR+ +E       K+A+LQ    ++E+E +++ +  E L  S  K E LE   
Sbjct: 699  LDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758

Query: 491  -------KAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAK 543
                   + ++  LE   +++     +L++ LE  N+ L +K  E  + + K + QL  +
Sbjct: 759  QGLDIENQRLQKTLENSNKKIQQLESELQD-LEMENQTL-QKNLEELKISSKRLEQLEKE 816

Query: 544  NKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEE----------- 592
            NK  ++E  +LE +       N+  R+  EI+D  L     K+  LE+E           
Sbjct: 817  NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876

Query: 593  ----LKKKQVYVDKVEKMQQALVQLQAACEKREQL-EHRLRT--------RLERELESLR 639
                ++ K++  +  E +++A + ++     RE L   +L+T        +L  ELE + 
Sbjct: 877  KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936

Query: 640  IQQRQ--GNCQPTNVSEYN------AAALMELLREKEERILALEA---DMTKWEQKYLEE 688
            + + +   + Q T+ S Y        + L + L  KEE+I ALEA   + T + Q+  +E
Sbjct: 937  LNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 996

Query: 689  NVMRHFALDAAATVAAQRDTTVISHSPNTS-YDTALEARIQKEEEEILMANKRCLDMEGR 747
              ++    +  A    Q +  ++  SP  S  D   E   Q+   E+L    R +++E  
Sbjct: 997  --LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1054

Query: 748  IKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTL 805
              TL A   EK A+   L+Q   +  +   Q+  ++  +  +S+    + L + ++ L
Sbjct: 1055 NATLQA---EKQALKTQLKQLETQNNNLQAQILALQ--RQTVSLQEQNTTLQTQNAKL 1107



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 82/355 (23%), Positives = 147/355 (41%), Gaps = 42/355 (11%)

Query: 435 QQMVEILSDEN--RNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEK- 491
           Q+ + +LSD    R  R EL+   EK  R+ K+E+E+ R  E   ++    ++ E L++ 
Sbjct: 293 QENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKED 352

Query: 492 ---------AMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFA 542
                     + ++LEG   R    +   +E L+   K L + E E   D RK I +L  
Sbjct: 353 NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAK-LHDMEMERDMD-RKKIEELME 410

Query: 543 KN-------KESQREKEKLEAELATARSTNE-DQRRHIEIRDQALSNAQAKVVKLEEELK 594
           +N       K+S  E   L  EL     T+E  +     +  +      ++++KLE E +
Sbjct: 411 ENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQ 470

Query: 595 KKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQG--NCQPTNV 652
                V+++     ++    +   K E+   RL  ++E  LE+  +Q++Q   NCQ  + 
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE-ILENEIVQEKQSLQNCQNLSK 529

Query: 653 SEYNAAA----LMELLREKEERILALEADMTKWEQKYLEENV---MRHFALDAAATVAAQ 705
                 A     +E LRE  ER    +  + + E ++L + V    +   + A A V   
Sbjct: 530 DLMKEKAQLEKTIETLRENSER----QIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585

Query: 706 RDTTVISHSPNTSYDTAL------EARIQKEEEEILMANKRCLDMEGRIKTLHAQ 754
                I H       + L      + +I+KE E      +R  ++E  +  L  +
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 79/360 (21%), Positives = 147/360 (40%), Gaps = 30/360 (8%)

Query: 433 RAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKA 492
           R  + VEIL +E    +Q L+ C      L K + ++++  E      +   K    E  
Sbjct: 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 561

Query: 493 MRNKLEGEIRRMHDFNRDLRER-LETANKQLAEKEYEGS------EDTRKTISQLFAKNK 545
             N+    +R+    + + R + +E  NK L E   E S      E  ++ I +     K
Sbjct: 562 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 621

Query: 546 ESQREKEKLEAELATARSTNEDQRR---HIEIRDQALSNAQAKVVKLEEELKKKQVYVDK 602
           E     E+LE EL      NE  ++   +++I  + +   + +  +LE E +K +  +D 
Sbjct: 622 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 681

Query: 603 VEKMQQALVQLQAACEKREQLEHRLRTRLERELESLR-IQQRQGNCQPTNVSEYNAAALM 661
            + +     QL++  ++  QL+      L R +ESL+    +    Q  N          
Sbjct: 682 FKNL---TFQLESLEKENSQLDEE-NLELRRNVESLKCASMKMAQLQLEN---------K 728

Query: 662 ELLREKEERILALEADMTKWEQKYLEENVMRHFALD---AAATVAAQRDTTVISHSPNTS 718
           EL  EKE+    LE  + K   K  E   + +  LD          +     I    +  
Sbjct: 729 ELESEKEQLKKGLE--LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786

Query: 719 YDTALEAR-IQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTE 777
            D  +E + +QK  EE+ +++KR   +E   K+L  +  + +   K L++ +++   + E
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 93/413 (22%), Positives = 174/413 (42%), Gaps = 38/413 (9%)

Query: 387 HHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENR 446
           H   H     Q P   PG     M R + S        AD  A + R +Q +E  +++  
Sbjct: 222 HFLPHASSSAQSPCGSPG-----MKRTE-SRQHLSVELADAKAKIRRLRQELEEKTEQLL 275

Query: 447 NLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMR-NKLEGEI---- 501
           + +QELE    ++ RLQ  +  +  +S+A    +         EKA+R +KLE E+    
Sbjct: 276 DCKQELEQMEIELKRLQ--QENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333

Query: 502 RRMHD--FNRDLRERLETANKQLAEKE---YEGSEDTRKTISQLFAKNKESQREKEKLEA 556
            R+HD  F +   E L+  N+ L E +    +  E TR    +L    KE+ + K KL  
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLH- 392

Query: 557 ELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAA 616
           ++   R  +  +   +   +  L  AQ + +     L  +   + +  ++ +A  Q    
Sbjct: 393 DMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA-PQKSLG 451

Query: 617 CEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKE---ERILA 673
            E  E    RL  +LE E +SL     +      +V E NA+ ++++ +E +   +++  
Sbjct: 452 HEVNELTSSRL-LKLEMENQSLTKTVEELRTTVDSV-EGNASKILKMEKENQRLSKKVEI 509

Query: 674 LEADMTKWEQ-----KYLEENVMRHFALDAAATVAAQRDTT----VISHSPNTSYDTALE 724
           LE ++ + +Q     + L +++M+  A     T+   R+ +     I    N   +  + 
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKA-QLEKTIETLRENSERQIKILEQENEHLNQTVS 568

Query: 725 ARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTE 777
           +  Q+ +   + A  R  D+E   K LH  I E  + +  ++   R+   + E
Sbjct: 569 SLRQRSQ---ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 10/130 (7%)

Query: 432  SRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEK 491
            S+  +  E+L  +++NL+  L     +  RL   E E  ++ E Y+ L  +S+K    + 
Sbjct: 1255 SQLLKETEVLQTDHKNLKSLLNNSKLEQTRL---EAEFSKLKEQYQQLDITSTKLNN-QC 1310

Query: 492  AMRNKLEGEIRRMHDFNRDLRERLETA---NKQLAEKEYEGSEDTRKTISQLFAKNKESQ 548
             + ++L+G +    + NR L ++++T    N+ L E+  E  +       Q   K  E +
Sbjct: 1311 ELLSQLKGNLE---EENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1367

Query: 549  REKEKLEAEL 558
            R+KEKLE ++
Sbjct: 1368 RQKEKLEEKI 1377



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 75/394 (19%), Positives = 157/394 (39%), Gaps = 64/394 (16%)

Query: 465 VETEIQRVSEAYENLVK------SSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETA 518
           V   IQ V+   EN+        +   +E +E  ++N +   ++R+ D  RD  E  ET 
Sbjct: 156 VAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLKN-MALHLKRLID-ERD--EHSETI 211

Query: 519 NKQLAEKEY-----EGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIE 573
            +   E++        S   +        K  ES   ++ L  ELA A++     R+ +E
Sbjct: 212 IELSEERDGLHFLPHASSSAQSPCGSPGMKRTES---RQHLSVELADAKAKIRRLRQELE 268

Query: 574 IRDQALSNAQAKVVKLEEELKKKQ--------------VYVDKVEKMQQALVQLQAACEK 619
            + + L + + ++ ++E ELK+ Q              +Y D+++ +++  V++    +K
Sbjct: 269 EKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRV----DK 324

Query: 620 REQLEHRLRTRL-ERELESLRIQQRQGNCQ-----PTNVSEY--NAAALMELLREKEERI 671
            E    R + RL + E    R+++ + + Q      T + +      A  + L E E+  
Sbjct: 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 384

Query: 672 LALEADMTKWE------QKYLEENVMRHFALDAAATVAAQRD------------TTVISH 713
           L L+A +   E      +K +EE +  +  L+ A   +                T+ +S 
Sbjct: 385 LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSE 444

Query: 714 SPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEP 773
           +P  S    +         ++ M N+        ++T    +    + I  +++ +++  
Sbjct: 445 APQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLS 504

Query: 774 SKTEQL--SCMRPAKSLMSISNAGSGLLSHSSTL 805
            K E L    ++  +SL +  N    L+   + L
Sbjct: 505 KKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL 538


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 32/201 (15%)

Query: 880  PISVPAPVAAAATAAAITATAATITTTMVAAAP-VAVAAAAAPAAAAAPSPATAAATAAA 938
            P+SVPAPV  +       AT+    +  +A  P +A A  + P   +  +P + +A+   
Sbjct: 224  PLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLV 283

Query: 939  VSPAAA---GQIPAAASVASAAAVAPSAAAAAAVQ--VAPAAP----APVPAPALVPVPA 989
              PA+A   G +P +A   +  +V  SA   A +Q  V P+AP    APVP P L P+PA
Sbjct: 284  PVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA 343

Query: 990  ---PAA-AQASAPAQTQAPTSAPAVAPT----------PAPTPTPAVAQAEVP------- 1028
               PAA A  S P  T  P+S P   PT          PAPTP P    A  P       
Sbjct: 344  STPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPA 403

Query: 1029 ASPATGPGPHRLSIPSLTCNP 1049
            A P + P P   S+ S  C P
Sbjct: 404  AIPTSAPIPASFSL-SRVCFP 423



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 21/202 (10%)

Query: 872  SNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA-APAAAAAPSPA 930
            +N +   API  PAP +A+   +   A    ++      APV  +       A + P+P+
Sbjct: 194  TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVP----APVPHSGLVPVQVATSVPAPS 249

Query: 931  TAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAP----APVPAPALVP 986
               A   A++PA    +P   S ++  +V+ S          P+ P    AP PAP  VP
Sbjct: 250  PPLAPVPALAPAPPS-VPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVP 308

Query: 987  VPAPAAAQASAPAQTQAPT------SAPAVAPTPAPTPTPAVAQAEVP---ASPATGPGP 1037
            V AP  A   AP    APT        P +AP PA TP  A A   VP    +P++GP  
Sbjct: 309  VSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPS 368

Query: 1038 HRLSIPSL--TCNPDKTDGPVF 1057
                IP+   T  P  T  P+F
Sbjct: 369  TPTLIPAFAPTPVPAPTPAPIF 390



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 61/224 (27%), Positives = 86/224 (38%), Gaps = 25/224 (11%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAA-IT 897
            S P+P PP  P+ +      S          ++SN  +  A + VP P +A  +    ++
Sbjct: 244  SVPAPSPPLAPVPALAPAPPSVPTLI-----SDSNPLSVSASVLVPVPASAPPSGPVPLS 298

Query: 898  ATAATITTTMVAAAPVAVAAA----AAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASV 953
            A A    +  V+A P+A+  A    +AP    AP P    A   A +P AA   PA  SV
Sbjct: 299  APAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAA---PAPPSV 355

Query: 954  ASAAAVAPSAAAAAAVQVAPAAPAPVPA--------PALVPVPAPAAAQASAPAQTQAPT 1005
                    S   +    +   AP PVPA        PA  P P PAA  A+ P     P 
Sbjct: 356  PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPA--PTPMPAATPAAIPTSAPIPA 413

Query: 1006 SAPAVAPTPAPTPTPAVAQAEVPASPAT--GPGPHRLSIPSLTC 1047
            S             PA+ +  +   P T   P    + IP  +C
Sbjct: 414  SFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSC 457



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 64/216 (29%), Positives = 85/216 (39%), Gaps = 29/216 (13%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +P PPS P L + S   S   S        +  +  V P+S PAP   +   +A     A
Sbjct: 259  APAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV-PLSAPAPAPLSVPVSA--PPLA 315

Query: 902  TITTTMVAAAPVAVAAAA-----APAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASA 956
             I   +  +AP  V A       AP  A+ P  A A  +    +P  +   P+  ++  A
Sbjct: 316  LIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPA 375

Query: 957  AAVAPSAAAAAAVQVAPAAPAPVPA--PALVPVPAPAAAQ----------ASAPAQTQAP 1004
             A  P  A   A    PA P P+PA  PA +P  AP  A           A APA  + P
Sbjct: 376  FAPTPVPAPTPAPIFTPA-PTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVP 434

Query: 1005 TS-APAVAPTPAP----TPTPAVAQAEVPASPATGP 1035
             S  P    TP+      P P+  Q   P S AT P
Sbjct: 435  LSFQPGTVLTPSQPLVYIPPPSCGQ---PLSVATLP 467



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 91/361 (25%), Positives = 125/361 (34%), Gaps = 84/361 (23%)

Query: 781  CMRPAKSLMSISNAGSGLLSHSSTLTGSPI------MEEKRDDKSWKGSLGILLGGDYRA 834
            C+  + S + ++  GSG  +  +   GS         E+K DD   K         DY  
Sbjct: 52   CVSSSFSKVELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKM--------DYAG 103

Query: 835  EYVPSTPSPVPPSTP--------LLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAP 886
                +    VP S+P          SA +     DCS  T   T+ +K    +P  V A 
Sbjct: 104  NVAEAEGFLVPLSSPGDGLKLPASDSAEASNSRADCSW-TPLNTQMSKQVDCSPAGVKAL 162

Query: 887  VAAAATAAAITATAATITTTMVAAAPVAVAA---AAAPAAAAAPSPATAAATAAAVSPAA 943
             +        T   AT+ T +     + +     +  PA    P+P +A+   +      
Sbjct: 163  DSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHS------ 216

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP------VPAPA-------------- 983
               +P A  V  +       +    VQVA + PAP      VPA A              
Sbjct: 217  ---VPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSN 273

Query: 984  --------LVPVPA------PAAAQASAPAQTQAPTSAPAVA------PTPAPT----PT 1019
                    LVPVPA      P    A APA    P SAP +A      P  APT    P 
Sbjct: 274  PLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPV 333

Query: 1020 PAVAQAEVPAS-PATGPGPHRLSIPSLT--CNPDKTDG--PVFHSNTLERKTPIQILGQE 1074
            P    A +PAS P   P P  + +P+ T    P  T    P F    +   TP  I    
Sbjct: 334  PTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPA 393

Query: 1075 P 1075
            P
Sbjct: 394  P 394



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/245 (24%), Positives = 86/245 (35%), Gaps = 38/245 (15%)

Query: 839  STP--SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAV-APISVPAPVAAAATAAA 895
            STP  +P PPS P+ +    +G     T       +   A   API  PAP    A   A
Sbjct: 344  STPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPA 403

Query: 896  ITATAATITTTMVAAAPVAVAAAAAPAAAAAP------SPATAAATAAAVSPAAAGQ--- 946
               T+A I  +  + + V   AA APA    P      +  T +     + P + GQ   
Sbjct: 404  AIPTSAPIPASF-SLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLS 462

Query: 947  ---IPAAASVASAAA--VAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQA------ 995
               +P    V+S     V PS      +    A+P     P    V  P  + +      
Sbjct: 463  VATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLE 522

Query: 996  ------SAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEV--------PASPATGPGPHRLS 1041
                  ++P+ +     AP   P P    +   A A+V        PA   +   PH   
Sbjct: 523  VNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAK 582

Query: 1042 IPSLT 1046
            +PS T
Sbjct: 583  MPSGT 587


>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sapiens]
          Length = 254

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 61/151 (40%), Positives = 75/151 (49%), Gaps = 13/151 (8%)

Query: 879  APISVPAPVA---AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAAT 935
            AP +V  PVA   A A A    A A     ++ AA P+AVA    PAA   P+    AA+
Sbjct: 60   APAAVRPPVAGPPATAPAVVCPAAAGPSAASLRAANPLAVA----PAAVRRPAATLGAAS 115

Query: 936  AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQA 995
             AAV+PAA     A+ S AS  A +P+AAA AA   A AAP  V   A  P  A   + A
Sbjct: 116  PAAVAPAAVCPAAASPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQSVA 175

Query: 996  SAPAQTQA---PTSAPAVAPTPAPTPTPAVA 1023
             +PA   A   P S+PA    PAP   P +A
Sbjct: 176  ESPATPLAIAQPVSSPA---APAPCAVPPLA 203



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 66/184 (35%), Positives = 88/184 (47%), Gaps = 15/184 (8%)

Query: 876  AAVAPISVPA---PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA----AAAAPS 928
            AA  P + PA   P AA  +AA++ A    +        PVA   A APA    AAA PS
Sbjct: 28   AAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAAVRPPVAGPPATAPAVVCPAAAGPS 87

Query: 929  PATA-AATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPV 987
             A+  AA   AV+PAA  +  A    AS AAVAP+A   AA   +P+A +   A      
Sbjct: 88   AASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVCPAA--ASPSAASLCAASPTAAA 145

Query: 988  PAPAAAQASAPAQTQAPTSAPAVA--PTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSL 1045
            PA A+  A+AP       +APA A   + A +P   +A A+  +SPA    P   ++P L
Sbjct: 146  PAAASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIAQPVSSPA---APAPCAVPPL 202

Query: 1046 TCNP 1049
               P
Sbjct: 203  AAEP 206



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 58/159 (36%), Positives = 71/159 (44%), Gaps = 8/159 (5%)

Query: 838 PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTA---AVAPISVPAPVAAAATAA 894
           P  P+P     P+    +   +  C         S + A   AVAP +V  P  AA   A
Sbjct: 56  PLVPAPAAVRPPVAGPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAVRRP--AATLGA 113

Query: 895 AITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAA-AVSPAAAGQIPAAASV 953
           A  A  A       AA+P A +  AA   AAAP+ A+ AA A  AV+PAAA   PAAA V
Sbjct: 114 ASPAAVAPAAVCPAAASPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAA--PAAACV 171

Query: 954 ASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAA 992
            S A    +  A A    +PAAPAP   P L   P   A
Sbjct: 172 QSVAESPATPLAIAQPVSSPAAPAPCAVPPLAAEPTALA 210



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 49/138 (35%), Positives = 65/138 (47%), Gaps = 5/138 (3%)

Query: 869  GTESNKTAAVAPISVPAPVAAAATAAAITATAATI---TTTMVAAAPVAVAAAAAPAAAA 925
            G  +   A V P +     A+   A  +    A +     T+ AA+P AVA AA   AAA
Sbjct: 70   GPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVCPAAA 129

Query: 926  APSPAT-AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL 984
            +PS A+  AA+  A +PAAA    AA    + AA AP+AA   +V  +PA P  +  P  
Sbjct: 130  SPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIAQPVS 189

Query: 985  VP-VPAPAAAQASAPAQT 1001
             P  PAP A    A   T
Sbjct: 190  SPAAPAPCAVPPLAAEPT 207



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 58/139 (41%), Positives = 71/139 (51%), Gaps = 12/139 (8%)

Query: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAA--APSPATAAA 934
            A AP +V  P AA  +AA++ A             P A   AA+PAA A  A  PA A+ 
Sbjct: 73   ATAP-AVVCPAAAGPSAASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVCPAAASP 131

Query: 935  TAA---AVSPAAAGQIPAAASVASAA--AVAPSAAAAAAVQVAPAAPAP-VPAPALVPVP 988
            +AA   A SP AA   PAAAS A+AA  AV P+AAA AA  V   A +P  P     PV 
Sbjct: 132  SAASLCAASPTAAA--PAAASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIAQPVS 189

Query: 989  APAA-AQASAPAQTQAPTS 1006
            +PAA A  + P     PT+
Sbjct: 190  SPAAPAPCAVPPLAAEPTA 208



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 58/177 (32%), Positives = 69/177 (38%), Gaps = 9/177 (5%)

Query: 905  TTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAA 964
            +T  AA       AAAPAA   P+    AA  A V PAAAG  P+AAS+ +A  + P+ A
Sbjct: 5    STRAAAKTSVRRPAAAPAAVRPPAAGPPAAAPAVVYPAAAG--PSAASLCAANPLVPAPA 62

Query: 965  AAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQ 1024
            A       P A  P  APA+V    PAAA  SA +   A   A A A    P  T   A 
Sbjct: 63   AVRP----PVAGPPATAPAVV---CPAAAGPSAASLRAANPLAVAPAAVRRPAATLGAAS 115

Query: 1025 AEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMVE 1081
                A  A  P     S  SL         P   S        +      P A  V+
Sbjct: 116  PAAVAPAAVCPAAASPSAASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQ 172



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 33/89 (37%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 947  IPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTS 1006
            I  +   A+  +V   AAA AAV+  PAA  P  APA+V    PAAA  SA +   A   
Sbjct: 2    IKFSTRAAAKTSVRRPAAAPAAVR-PPAAGPPAAAPAVV---YPAAAGPSAASLCAANPL 57

Query: 1007 APAVAPTPAPTPTPAVAQAEVPASPATGP 1035
             PA A    P   P      V    A GP
Sbjct: 58   VPAPAAVRPPVAGPPATAPAVVCPAAAGP 86


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
            sapiens]
          Length = 1870

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 97/417 (23%), Positives = 186/417 (44%), Gaps = 61/417 (14%)

Query: 441  LSDENRNLRQELEG---CYEKVARLQ----KVETEIQRVSEAYENLVKSSSKREALE--- 490
            L +EN  LR+ +E       K+A+LQ    ++E+E +++ +  E L  S  K E LE   
Sbjct: 699  LDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758

Query: 491  -------KAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAK 543
                   + ++  LE   +++     +L++ LE  N+ L +K  E  + + K + QL  +
Sbjct: 759  QGLDIENQRLQKTLENSNKKIQQLESELQD-LEMENQTL-QKNLEELKISSKRLEQLEKE 816

Query: 544  NKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEE----------- 592
            NK  ++E  +LE +       N+  R+  EI+D  L     K+  LE+E           
Sbjct: 817  NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876

Query: 593  ----LKKKQVYVDKVEKMQQALVQLQAACEKREQL-EHRLRT--------RLERELESLR 639
                ++ K++  +  E +++A + ++     RE L   +L+T        +L  ELE + 
Sbjct: 877  KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936

Query: 640  I-QQRQGNCQPTNVSEYN------AAALMELLREKEERILALEA---DMTKWEQKYLEEN 689
            + ++R  + + +    Y        + L + L  KEE+I ALEA   + T + Q+  +E 
Sbjct: 937  LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE- 995

Query: 690  VMRHFALDAAATVAAQRDTTVISHSPNTS-YDTALEARIQKEEEEILMANKRCLDMEGRI 748
             ++    +  A    Q +  ++  SP  S  D   E   Q+   E+L    R +++E   
Sbjct: 996  -LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1054

Query: 749  KTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTL 805
             TL A   EK A+   L+Q   +  +   Q+  ++  +  +S+    + L + ++ L
Sbjct: 1055 ATLQA---EKQALKTQLKQLETQNNNLQAQILALQ--RQTVSLQEQNTTLQTQNAKL 1106



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 82/355 (23%), Positives = 147/355 (41%), Gaps = 42/355 (11%)

Query: 435 QQMVEILSDEN--RNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEK- 491
           Q+ + +LSD    R  R EL+   EK  R+ K+E+E+ R  E   ++    ++ E L++ 
Sbjct: 293 QENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKED 352

Query: 492 ---------AMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFA 542
                     + ++LEG   R    +   +E L+   K L + E E   D RK I +L  
Sbjct: 353 NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAK-LHDMEMERDMD-RKKIEELME 410

Query: 543 KN-------KESQREKEKLEAELATARSTNE-DQRRHIEIRDQALSNAQAKVVKLEEELK 594
           +N       K+S  E   L  EL     T+E  +     +  +      ++++KLE E +
Sbjct: 411 ENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQ 470

Query: 595 KKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQG--NCQPTNV 652
                V+++     ++    +   K E+   RL  ++E  LE+  +Q++Q   NCQ  + 
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE-ILENEIVQEKQSLQNCQNLSK 529

Query: 653 SEYNAAA----LMELLREKEERILALEADMTKWEQKYLEENV---MRHFALDAAATVAAQ 705
                 A     +E LRE  ER    +  + + E ++L + V    +   + A A V   
Sbjct: 530 DLMKEKAQLEKTIETLRENSER----QIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585

Query: 706 RDTTVISHSPNTSYDTAL------EARIQKEEEEILMANKRCLDMEGRIKTLHAQ 754
                I H       + L      + +I+KE E      +R  ++E  +  L  +
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 79/360 (21%), Positives = 147/360 (40%), Gaps = 30/360 (8%)

Query: 433 RAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKA 492
           R  + VEIL +E    +Q L+ C      L K + ++++  E      +   K    E  
Sbjct: 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 561

Query: 493 MRNKLEGEIRRMHDFNRDLRER-LETANKQLAEKEYEGS------EDTRKTISQLFAKNK 545
             N+    +R+    + + R + +E  NK L E   E S      E  ++ I +     K
Sbjct: 562 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 621

Query: 546 ESQREKEKLEAELATARSTNEDQRR---HIEIRDQALSNAQAKVVKLEEELKKKQVYVDK 602
           E     E+LE EL      NE  ++   +++I  + +   + +  +LE E +K +  +D 
Sbjct: 622 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 681

Query: 603 VEKMQQALVQLQAACEKREQLEHRLRTRLERELESLR-IQQRQGNCQPTNVSEYNAAALM 661
            + +     QL++  ++  QL+      L R +ESL+    +    Q  N          
Sbjct: 682 FKNL---TFQLESLEKENSQLDEE-NLELRRNVESLKCASMKMAQLQLEN---------K 728

Query: 662 ELLREKEERILALEADMTKWEQKYLEENVMRHFALD---AAATVAAQRDTTVISHSPNTS 718
           EL  EKE+    LE  + K   K  E   + +  LD          +     I    +  
Sbjct: 729 ELESEKEQLKKGLE--LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786

Query: 719 YDTALEAR-IQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTE 777
            D  +E + +QK  EE+ +++KR   +E   K+L  +  + +   K L++ +++   + E
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 93/413 (22%), Positives = 174/413 (42%), Gaps = 38/413 (9%)

Query: 387 HHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENR 446
           H   H     Q P   PG     M R + S        AD  A + R +Q +E  +++  
Sbjct: 222 HFLPHASSSAQSPCGSPG-----MKRTE-SRQHLSVELADAKAKIRRLRQELEEKTEQLL 275

Query: 447 NLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMR-NKLEGEI---- 501
           + +QELE    ++ RLQ  +  +  +S+A    +         EKA+R +KLE E+    
Sbjct: 276 DCKQELEQMEIELKRLQ--QENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYK 333

Query: 502 RRMHD--FNRDLRERLETANKQLAEKE---YEGSEDTRKTISQLFAKNKESQREKEKLEA 556
            R+HD  F +   E L+  N+ L E +    +  E TR    +L    KE+ + K KL  
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLH- 392

Query: 557 ELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAA 616
           ++   R  +  +   +   +  L  AQ + +     L  +   + +  ++ +A  Q    
Sbjct: 393 DMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEA-PQKSLG 451

Query: 617 CEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKE---ERILA 673
            E  E    RL  +LE E +SL     +      +V E NA+ ++++ +E +   +++  
Sbjct: 452 HEVNELTSSRL-LKLEMENQSLTKTVEELRTTVDSV-EGNASKILKMEKENQRLSKKVEI 509

Query: 674 LEADMTKWEQ-----KYLEENVMRHFALDAAATVAAQRDTT----VISHSPNTSYDTALE 724
           LE ++ + +Q     + L +++M+  A     T+   R+ +     I    N   +  + 
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKA-QLEKTIETLRENSERQIKILEQENEHLNQTVS 568

Query: 725 ARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTE 777
           +  Q+ +   + A  R  D+E   K LH  I E  + +  ++   R+   + E
Sbjct: 569 SLRQRSQ---ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 67/371 (18%), Positives = 150/371 (40%), Gaps = 47/371 (12%)

Query: 430  IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL 489
            +V RA   ++ L     +L  E     +    L+K+  E++++    E L+      +  
Sbjct: 893  LVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDR 952

Query: 490  EKAMRNKLEGEIRRMHDFNRD----LRERLETA---NKQLAEKEYEGSEDTRKTISQLFA 542
             K + +KLE  +++  +   +    L  RLE +   N+QL ++         KT+ + + 
Sbjct: 953  YKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE--------LKTVKKNYE 1004

Query: 543  KNKESQREKEKLEAELATA-------RSTNEDQRRHIEIRDQAL----SNAQAKVVKLEE 591
              K+ Q E+  +++    +       R + E  R  ++++D+ +    +NA  +  K   
Sbjct: 1005 ALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQAL 1064

Query: 592  ELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTN 651
            + + KQ+         Q L   +     +EQ      T L+ +   L+++    N Q T+
Sbjct: 1065 KTQLKQLETQNNNLQAQILALQRQTVSLQEQ-----NTTLQTQNAKLQVENSTLNSQSTS 1119

Query: 652  VSEYNAAALME--LLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTT 709
            +   NA  L++   L  + E ++    D+       ++++       +     A++ ++ 
Sbjct: 1120 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ---ASEYESL 1176

Query: 710  VISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS 769
            +  H    S    LE     E  ++     + L  +G+++ L       + M+KV Q++ 
Sbjct: 1177 ISKHGTLKSAHKNLEV----EHRDLEDRYNQLLKQKGQLEDL-------EKMLKVEQEKM 1225

Query: 770  RKEPSKTEQLS 780
              E    E ++
Sbjct: 1226 LLENKNHETVA 1236



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 10/130 (7%)

Query: 432  SRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEK 491
            S+  +  E+L  +++NL+  L     +  RL   E E  ++ E Y+ L  +S+K    + 
Sbjct: 1254 SQLLKETEVLQTDHKNLKSLLNNSKLEQTRL---EAEFSKLKEQYQQLDITSTKLNN-QC 1309

Query: 492  AMRNKLEGEIRRMHDFNRDLRERLETA---NKQLAEKEYEGSEDTRKTISQLFAKNKESQ 548
             + ++L+G +    + NR L ++++T    N+ L E+  E  +       Q   K  E +
Sbjct: 1310 ELLSQLKGNLE---EENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1366

Query: 549  REKEKLEAEL 558
            R+KEKLE ++
Sbjct: 1367 RQKEKLEEKI 1376



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 75/394 (19%), Positives = 157/394 (39%), Gaps = 64/394 (16%)

Query: 465 VETEIQRVSEAYENLVK------SSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETA 518
           V   IQ V+   EN+        +   +E +E  ++N +   ++R+ D  RD  E  ET 
Sbjct: 156 VAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLKN-MALHLKRLID-ERD--EHSETI 211

Query: 519 NKQLAEKEY-----EGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIE 573
            +   E++        S   +        K  ES   ++ L  ELA A++     R+ +E
Sbjct: 212 IELSEERDGLHFLPHASSSAQSPCGSPGMKRTES---RQHLSVELADAKAKIRRLRQELE 268

Query: 574 IRDQALSNAQAKVVKLEEELKKKQ--------------VYVDKVEKMQQALVQLQAACEK 619
            + + L + + ++ ++E ELK+ Q              +Y D+++ +++  V++    +K
Sbjct: 269 EKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRV----DK 324

Query: 620 REQLEHRLRTRL-ERELESLRIQQRQGNCQ-----PTNVSEY--NAAALMELLREKEERI 671
            E    R + RL + E    R+++ + + Q      T + +      A  + L E E+  
Sbjct: 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 384

Query: 672 LALEADMTKWE------QKYLEENVMRHFALDAAATVAAQRD------------TTVISH 713
           L L+A +   E      +K +EE +  +  L+ A   +                T+ +S 
Sbjct: 385 LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSE 444

Query: 714 SPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEP 773
           +P  S    +         ++ M N+        ++T    +    + I  +++ +++  
Sbjct: 445 APQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLS 504

Query: 774 SKTEQL--SCMRPAKSLMSISNAGSGLLSHSSTL 805
            K E L    ++  +SL +  N    L+   + L
Sbjct: 505 KKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL 538


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
            sapiens]
          Length = 305

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 907  MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966
            ++A  PVAVA A +P    A         A    P+    +PA AS      V   A A 
Sbjct: 92   LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 149

Query: 967  AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
            A   VA    APV    L P PAPA A A APA   AP  APA AP PAP P PA
Sbjct: 150  APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P PVA A   +     AA  +   +  AP  + +   PA A+ P P    A A A +PA 
Sbjct: 95   PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 152

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
                P AA VA            A V VA  APAP PAPA  P PAP AA A APA    
Sbjct: 153  ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 192

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAE 1026
                PA AP PAP P P  A  E
Sbjct: 193  ----PAPAPAPAPAPAPDAAPQE 211



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 835  EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
            E +PS P P P STP                           A AP   PAPVAA   A 
Sbjct: 123  EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 161

Query: 895  AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 944
               A  A       A AP  A  AA APA A AP+PA A A A   +P  +         
Sbjct: 162  VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 221

Query: 945  -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
             GQ P A  + S  +  P+A  AA         A     A+  +  P  +   A  +  A
Sbjct: 222  RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 272

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
            P  +    P P P+P+ A     V  +P
Sbjct: 273  PEKSSGDVPAPCPSPSAAPGVGSVEQTP 300



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)

Query: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 933
            A  P++V   V+     AA +          + + PV   A+     P  A AP+PA A 
Sbjct: 94   APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 153

Query: 934  ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 992
              A   +P A   +  A + A A A AP+  AA A   APA APAP PAPA    P  +A
Sbjct: 154  VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 213

Query: 993  AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 1046
             Q +   Q      A  +    +  P    A     A+ A G    +LS P ++      
Sbjct: 214  EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 268

Query: 1047 --CNPDKTDGPV 1056
                P+K+ G V
Sbjct: 269  KRSAPEKSSGDV 280


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
            sapiens]
          Length = 305

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 907  MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966
            ++A  PVAVA A +P    A         A    P+    +PA AS      V   A A 
Sbjct: 92   LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 149

Query: 967  AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
            A   VA    APV    L P PAPA A A APA   AP  APA AP PAP P PA
Sbjct: 150  APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P PVA A   +     AA  +   +  AP  + +   PA A+ P P    A A A +PA 
Sbjct: 95   PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 152

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
                P AA VA            A V VA  APAP PAPA  P PAP AA A APA    
Sbjct: 153  ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 192

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAE 1026
                PA AP PAP P P  A  E
Sbjct: 193  ----PAPAPAPAPAPAPDAAPQE 211



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 835  EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
            E +PS P P P STP                           A AP   PAPVAA   A 
Sbjct: 123  EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 161

Query: 895  AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 944
               A  A       A AP  A  AA APA A AP+PA A A A   +P  +         
Sbjct: 162  VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 221

Query: 945  -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
             GQ P A  + S  +  P+A  AA         A     A+  +  P  +   A  +  A
Sbjct: 222  RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 272

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
            P  +    P P P+P+ A     V  +P
Sbjct: 273  PEKSSGDVPAPCPSPSAAPGVGSVEQTP 300



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)

Query: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 933
            A  P++V   V+     AA +          + + PV   A+     P  A AP+PA A 
Sbjct: 94   APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 153

Query: 934  ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 992
              A   +P A   +  A + A A A AP+  AA A   APA APAP PAPA    P  +A
Sbjct: 154  VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 213

Query: 993  AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 1046
             Q +   Q      A  +    +  P    A     A+ A G    +LS P ++      
Sbjct: 214  EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 268

Query: 1047 --CNPDKTDGPV 1056
                P+K+ G V
Sbjct: 269  KRSAPEKSSGDV 280


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
            sapiens]
          Length = 316

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 48/115 (41%), Positives = 53/115 (46%), Gaps = 2/115 (1%)

Query: 907  MVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966
            ++A  PVAVA A +P    A         A    P+    +PA AS      V   A A 
Sbjct: 103  LLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVP--VPAPASTPPPVPVLAPAPAP 160

Query: 967  AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
            A   VA    APV    L P PAPA A A APA   AP  APA AP PAP P PA
Sbjct: 161  APAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 57/143 (39%), Positives = 64/143 (44%), Gaps = 26/143 (18%)

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P PVA A   +     AA  +   +  AP  + +   PA A+ P P    A A A +PA 
Sbjct: 106  PRPVAVAVAVSPPLEPAAE-SLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA- 163

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
                P AA VA            A V VA  APAP PAPA  P PAP AA A APA    
Sbjct: 164  ----PVAAPVA------------APVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA---- 203

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAE 1026
                PA AP PAP P P  A  E
Sbjct: 204  ----PAPAPAPAPAPAPDAAPQE 222



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 61/208 (29%), Positives = 76/208 (36%), Gaps = 41/208 (19%)

Query: 835  EYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
            E +PS P P P STP                           A AP   PAPVAA   A 
Sbjct: 134  EQLPSVPVPAPASTP---------------------PPVPVLAPAPAPAPAPVAAPVAAP 172

Query: 895  AITATAATITTTMVAAAPV-AVAAAAAPAAAAAPSPATAAATAAAVSPAAA--------- 944
               A  A       A AP  A  AA APA A AP+PA A A A   +P  +         
Sbjct: 173  VAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQ 232

Query: 945  -GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
             GQ P A  + S  +  P+A  AA         A     A+  +  P  +   A  +  A
Sbjct: 233  RGQEPLADQLHSGISGRPAAGTAA---------ASANGAAIKKLSGPLISDFFAKRKRSA 283

Query: 1004 PTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
            P  +    P P P+P+ A     V  +P
Sbjct: 284  PEKSSGDVPAPCPSPSAAPGVGSVEQTP 311



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 17/192 (8%)

Query: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAA 933
            A  P++V   V+     AA +          + + PV   A+     P  A AP+PA A 
Sbjct: 105  APRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAP 164

Query: 934  ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAA 992
              A   +P A   +  A + A A A AP+  AA A   APA APAP PAPA    P  +A
Sbjct: 165  VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224

Query: 993  AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT------ 1046
             Q +   Q      A  +    +  P    A     A+ A G    +LS P ++      
Sbjct: 225  EQGANQGQRGQEPLADQLHSGISGRPAAGTA-----AASANGAAIKKLSGPLISDFFAKR 279

Query: 1047 --CNPDKTDGPV 1056
                P+K+ G V
Sbjct: 280  KRSAPEKSSGDV 291


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 86/276 (31%), Positives = 108/276 (39%), Gaps = 48/276 (17%)

Query: 831  DYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVP-APVAA 889
            D  A  V +   P  P+  + +    T         E  T  +  AAV P   P +P AA
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT--SPAAAVPPPEEPTSPAAA 1045

Query: 890  AATAAAITATAATITTTMVAAAPVAVAAA---AAPAAAAAPSPATAAATAAAV------- 939
              T    T+ AA + T     +P A           AAA P+P    + AAAV       
Sbjct: 1046 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1105

Query: 940  SPAAAGQIPAAASVASAAAVAPS----AAAAAAVQV-------APAAPAP---------V 979
            SPAAA  +P     AS AA  P+    A+ AAAV         APA P P         V
Sbjct: 1106 SPAAA--VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163

Query: 980  PAP-------ALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPA 1032
            P P       A VP PA +A+ A+  A  + PTS  A  PTPA      VA  E   SPA
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA----AMVATLEEFTSPA 1219

Query: 1033 TG--PGPHRLSIPSLTCNPDKTDGPVFHSNTLERKT 1066
                      S+ +   NP++   P     TLE  T
Sbjct: 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT 1255



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 76/269 (28%), Positives = 105/269 (39%), Gaps = 39/269 (14%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVP----APVAAAATAA 894
            + P+P  P++P  +A   T     S      T    T+  A +  P    +P AA  T  
Sbjct: 1071 AVPTPEEPTSP--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128

Query: 895  AITATAATITTTMVAAAPV---------AVAAAAAPA-------AAAAPSPATAAATAAA 938
               + AA + T    A P          A AA A P        AAA P+PA +A+ AA 
Sbjct: 1129 EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188

Query: 939  VSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP 998
            V+       PAA+    AA VA      +     P +  P    A V  P    + A+A 
Sbjct: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248

Query: 999  AQTQAPTSAPAVAPTP-------APTPTP--------AVAQAEVPASPATG-PGPHRLSI 1042
               + PTS+ A   TP       A  PTP        AV+  E PASPA   P P   +I
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308

Query: 1043 PSLTC-NPDKTDGPVFHSNTLERKTPIQI 1070
            P+ +   P+    P      +E  +PI +
Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGV 1337



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 63/209 (30%), Positives = 80/209 (38%), Gaps = 11/209 (5%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPI--SVPAPVAAAATAAAITAT 899
            +P  P TP  + H+       + +     E    AA  P      +P AA  T    T+ 
Sbjct: 970  TPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSP 1029

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAA-VSPAAAGQIPAAASVASAAA 958
            AA +       +P    AAA P      SPA A  T     SPAAA   P   +  +AA 
Sbjct: 1030 AAAVPPPEEPTSP----AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1085

Query: 959  VAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPT- 1017
              P    + A  V P    P    A VP P   A+ A+A    + P S  A  PTP    
Sbjct: 1086 PTPEEPTSPAAAV-PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144

Query: 1018 -PTPAVAQAEVPASPATG-PGPHRLSIPS 1044
             P PAV   E  AS A   P P   + P+
Sbjct: 1145 FPAPAVPTPEESASAAVAVPTPEESASPA 1173



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 69/233 (29%), Positives = 94/233 (40%), Gaps = 22/233 (9%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAI-- 896
            + P+P  P+ P  +  +   S   +       ES   AA    +VP P  +A+ AA +  
Sbjct: 1136 AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA----AVPTPAESASFAAVVAT 1191

Query: 897  ----TATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAAS 952
                T+ AA++ T    AA VA        AA+ P+    A+ AAAVS       PAAA 
Sbjct: 1192 LEEPTSPAASVPTP---AAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAA- 1247

Query: 953  VASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAP 1012
            V +      SAAA    +   +  A VP P     PA A +    PA   A    P VA 
Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307

Query: 1013 TPA---PTP-TPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNT 1061
             PA   PTP  PA+  A VP      P    + +P L  +      P+    T
Sbjct: 1308 IPAASVPTPEVPAIPAAAVPPMEEVSP----IGVPFLGVSAHTDSVPISEEGT 1356



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 74/249 (29%), Positives = 99/249 (39%), Gaps = 26/249 (10%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVP----APVAAAATAA 894
            + P+P  P++P  +A   T     S      T    T+  A +  P    +P AA  T  
Sbjct: 1045 AVPTPEEPTSP--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102

Query: 895  AITATAATITTTMVAAAPVAVAAAA---APAAAAAPSPATAAATAAAV-----SPAAAGQ 946
              T+ AA + T    A+P A        A  AAA P+P   A  A AV     S +AA  
Sbjct: 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162

Query: 947  IPAAASVASAAAVAPSAAAAAA-VQVAPAAPAPVPAPALVPVPAPAAA--------QASA 997
            +P     AS AA  P+ A +A+   V      P    A VP PA   A         AS 
Sbjct: 1163 VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV 1222

Query: 998  PAQTQAPTSAPAVAPTPAPT-PTPAVAQAEVPASPATGP-GPHRLSIPSLTC-NPDKTDG 1054
            P   +  + A AV+    PT P  AV   E P S A     P  LS P+ +   P++   
Sbjct: 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282

Query: 1055 PVFHSNTLE 1063
            P    + LE
Sbjct: 1283 PAAAVSNLE 1291



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 72/228 (31%), Positives = 93/228 (40%), Gaps = 22/228 (9%)

Query: 837  VPSTPSPVPPSTPLLSAHS---KTGSRDCSTQTERGTE-----SNKTAAVAPISVPAPVA 888
            VP+    VP  T  ++A S   +T     +  T+ G       S + AA+A I+VP    
Sbjct: 909  VPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALA-ITVPITEE 967

Query: 889  AAATAAAITATAATITTTMVAAAPVAVAAAAAPA--AAAAPSPATAAATAAAV------- 939
                   +T             A V V+    PA  AAA P+P    + AAAV       
Sbjct: 968  DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT 1027

Query: 940  SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPA 999
            SPAAA   P   +  +AA   P    + A  V P    P    A VP P    + A+A  
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAAVPTPEEPTSPAAAVP 1086

Query: 1000 QTQAPTSAPAVAPTP-APT-PTPAVAQAEVPASPATG-PGPHRLSIPS 1044
              + PTS  A  PTP  PT P  AV   E PASPA   P P   + P+
Sbjct: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA 1134



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 58/199 (29%), Positives = 74/199 (37%), Gaps = 8/199 (4%)

Query: 875  TAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAA---PSPAT 931
            T     +SVP   AA A  ++   TA  +   +      AVA  +   AA A   P    
Sbjct: 908  TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967

Query: 932  AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPA 991
                   V+PA     P     A+     P   A+ A  V P    P    A VP P   
Sbjct: 968  DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV-PTPEEPTSPAAAVPTPEEP 1026

Query: 992  AAQASAPAQTQAPTSAPAVAPTP-APT-PTPAVAQAEVPASPATG-PGPHRLSIPSLTC- 1047
             + A+A    + PTS  A  PTP  PT P  AV   E P SPA   P P   + P+    
Sbjct: 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086

Query: 1048 NPDKTDGPVFHSNTLERKT 1066
             P++   P     T E  T
Sbjct: 1087 TPEEPTSPAAAVPTPEEPT 1105



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 62/201 (30%), Positives = 82/201 (40%), Gaps = 31/201 (15%)

Query: 892  TAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAA 951
            TAAA++A        +  + P   AA AA ++    +PA AAA       A AG  P  A
Sbjct: 897  TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956

Query: 952  SVASAAAV------------------APSAAAAAAVQVA----PAAPAPVPAPALVPVPA 989
            ++A    +                  AP     AAV+V+    PA+PA     A VP P 
Sbjct: 957  ALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA-----AAVPTPE 1011

Query: 990  PAAAQASAPAQTQAPTS-APAVAPTPAPT-PTPAVAQAEVPASPATG-PGPHRLSIPSLT 1046
               + A+A    + PTS A AV P   PT P  AV   E P SPA   P P   + P+  
Sbjct: 1012 EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1071

Query: 1047 C-NPDKTDGPVFHSNTLERKT 1066
               P++   P     T E  T
Sbjct: 1072 VPTPEEPTSPAAAVPTPEEPT 1092



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 34/198 (17%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPI---------SVPAPVA 888
            P+ P+P   ++  ++  +   S   +       ES   AAV            SVP P A
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA 1207

Query: 889  AAATAAAITATAATITTTMVAAAPVAVAAAAA------PAAAAAPSPATAAATAAAV--- 939
              AT    T+ AA++ T+     P ++AAA +        AAA P+     ++AAAV   
Sbjct: 1208 MVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264

Query: 940  ----SPAAAGQIP-----AAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAP 990
                SPAA+   P      AA+V++    A  AAA    +VA    A VP P +  +PA 
Sbjct: 1265 EELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAA 1324

Query: 991  AAAQASAPAQTQAPTSAP 1008
            A      P +  +P   P
Sbjct: 1325 AV----PPMEEVSPIGVP 1338



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 64/225 (28%), Positives = 82/225 (36%), Gaps = 47/225 (20%)

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            +VPAP   A  AA +      I    + +       AAA    +AP  AT  A   +V  
Sbjct: 862  AVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA---VSAPERATVPAVTVSVPE 918

Query: 942  AAAGQIPAAASVASAAAVAPSAAAA----------------AAVQV------------AP 973
              A    A A+V+S    AP+ AAA                AA+ +             P
Sbjct: 919  GTA----AVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGP 974

Query: 974  AAPA--------PVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTP-APT-PTPAVA 1023
              PA        P  A   V  P   A+ A+A    + PTS  A  PTP  PT P  AV 
Sbjct: 975  VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034

Query: 1024 QAEVPASPATG-PGPHRLSIPSLTC-NPDKTDGPVFHSNTLERKT 1066
              E P SPA   P P   + P+     P++   P     T E  T
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1079



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 11/152 (7%)

Query: 838  PSTPSP-VPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAI 896
            P++P+  VP    +++   +  S   S  T     S   A   P    +P AA  T    
Sbjct: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254

Query: 897  TATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAA---AVSPAAAGQIPAAASV 953
            T++AA + T    ++P    AA+ P      SPA  AA +      SPAAA   P  A++
Sbjct: 1255 TSSAAAVLTPEELSSP----AASVPTPEEPASPA--AAVSNLEEPASPAAAVPTPEVAAI 1308

Query: 954  ASAAAVAPSAAAAAAVQVAPAAP-APVPAPAL 984
             +A+   P   A  A  V P    +P+  P L
Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFL 1340


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 49/131 (37%), Positives = 65/131 (49%), Gaps = 22/131 (16%)

Query: 914  AVAAAAAPAA-------AAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAA 966
            AVAA++APA         AAP+P     T A++ P+    +PA+         +PS  A 
Sbjct: 261  AVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST-------YSPSPGA- 312

Query: 967  AAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAP--TPTPAVAQ 1024
                 +P    P PAPA  P PAP  A   +P  T  P+ APA  P+PAP   P P+VA 
Sbjct: 313  ---NYSPTPYTPSPAPAYTPSPAP--AYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAY 367

Query: 1025 AEVPASPATGP 1035
            +  PA PA+ P
Sbjct: 368  SGGPAEPASRP 378



 Score = 33.9 bits (76), Expect = 0.86
 Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 24/168 (14%)

Query: 882  SVPAPVAAAATAAAITAT------AATITTTMVAA-APVAVAAAAAPAAAAAPSPATAAA 934
            + PAP     T A+I  +      A+T + +  A  +P     + APA   +P+PA   +
Sbjct: 279  AAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPS 338

Query: 935  TAAAVSPAAAGQIPAAASVASAAA---VAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPA 991
                 +P+     PA A   S A     APS A +       + P  V   +     AP 
Sbjct: 339  PVPTYTPS-----PAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPG 393

Query: 992  AAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEV------PASPAT 1033
             +  S   QT  P   PA   TPA    P +A+  V      PAS  T
Sbjct: 394  KSTTSISKQT-LPRGGPAY--TPAGPQVPPLARGTVQRAERFPASSRT 438


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 56/134 (41%), Positives = 59/134 (44%), Gaps = 18/134 (13%)

Query: 918  AAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPA 977
            A  PA   AP  A AAA AAA  P  A   P A   A+A A AP AAAAAA     A P+
Sbjct: 106  ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAAT----APPS 161

Query: 978  PVP----------APALVPVPAPAAAQASAPAQTQAPTSAPAVA----PTPAPTPTPAVA 1023
            P P          AP   P PAPAA  A AP         PAVA    P P P   PA  
Sbjct: 162  PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221

Query: 1024 QAEVPASPATGPGP 1037
            Q + P  P   P P
Sbjct: 222  QQQQPPPPQPQPPP 235



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 61/152 (40%), Positives = 64/152 (42%), Gaps = 12/152 (7%)

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            PAP  A   A A  A AA   T      P  VAAAA    A AP  A AAATA   SP  
Sbjct: 109  PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP---ARAPRAAAAAATAPP-SPGP 164

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAP--APVPAPALVPVPAPAAAQASAPAQT 1001
            A   P A   A  AA  P+ AA  AV   PA P  AP PA A    P P   Q  AP Q 
Sbjct: 165  AQPGPRAQRAAPLAAPPPAPAAPPAV-APPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ 223

Query: 1002 QAPTSAPAVAPTPAPTPTPAVAQAEVPASPAT 1033
            Q P       P P P P     +A   A P +
Sbjct: 224  QQPP-----PPQPQPPPEGGAVRAGGAARPVS 250



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 49/115 (42%), Positives = 51/115 (44%), Gaps = 21/115 (18%)

Query: 936  AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQA 995
            AA V P   G  P A   A   A  P+AAAAAA    P  PAP P PA V   APA A  
Sbjct: 96   AARVQPPRRGATPPAPPRAPRGA--PAAAAAAA---PPPTPAPPPPPAPVAAAAPARAPR 150

Query: 996  SAPAQTQAPTS-------------APAVAPTPAPTPTPAVAQAEVPASPATGPGP 1037
            +A A   AP S             AP  AP PAP   PAVA    PA P   P P
Sbjct: 151  AAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAP---PAGPRRAPPP 202



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 59/183 (32%), Positives = 68/183 (37%), Gaps = 28/183 (15%)

Query: 819 SWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAV 878
           S+KGS+        +     +TP P PP  P                  RG  +   AA 
Sbjct: 86  SYKGSISYRNAARVQPPRRGATP-PAPPRAP------------------RGAPAAAAAAA 126

Query: 879 -----APISVPAPVAAAATAAA--ITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPAT 931
                AP   PAPVAAAA A A    A AAT   +   A P   A  AAP AA  P+PA 
Sbjct: 127 PPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA 186

Query: 932 AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPA 991
             A A    P  A   P A +        P    A   Q  P  P P P P    V A  
Sbjct: 187 PPAVAPPAGPRRAP--PPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGG 244

Query: 992 AAQ 994
           AA+
Sbjct: 245 AAR 247



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 59/195 (30%), Positives = 74/195 (37%), Gaps = 30/195 (15%)

Query: 880  PISVPAP--VAAAATAAAITATAAT------ITTTMVA-----AAPVAVAAAAAPAAAAA 926
            P ++P P   AAA TAAA +++AA+      I  T+ +     A P              
Sbjct: 4    PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63

Query: 927  PSPA-TAAATAAAVSPAAAGQIPAAASVA--SAAAVAPSAAAAAAVQVAPAAPAPVPAPA 983
            P P  T A     +   A  ++    S++  +AA V P    A      P AP       
Sbjct: 64   PEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATP-PAPPRAPRG----- 117

Query: 984  LVPVPAPAAAQASAPAQTQA--PTSAPAVAPTPAPTPTPAVAQAEVPASPATG-PGPHRL 1040
                 APAAA A+AP  T A  P  AP  A  PA  P  A A A  P SP    PGP   
Sbjct: 118  -----APAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQ 172

Query: 1041 SIPSLTCNPDKTDGP 1055
                L   P     P
Sbjct: 173  RAAPLAAPPPAPAAP 187



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 47/179 (26%), Positives = 62/179 (34%), Gaps = 32/179 (17%)

Query: 919  AAPAAAAAPSPATAAATAAAVSPAAAGQ------IPAAASVASAAAVAPSAAAAAAVQVA 972
            A P A   P  A AA TAAA S +AA        +    S+ S  A  P       +   
Sbjct: 2    AGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKA-RPDLERICRMVRR 60

Query: 973  PAAPAP----------VPAPALVPVP-------------APAAAQASAPAQTQAPTSAPA 1009
               P P          +   A++ V               P    A+ PA  +AP  APA
Sbjct: 61   RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA 120

Query: 1010 VAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPI 1068
             A   AP PTPA      P + A      R +  + T  P  + GP       +R  P+
Sbjct: 121  AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP--SPGPAQPGPRAQRAAPL 177


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 69/232 (29%), Positives = 98/232 (42%), Gaps = 26/232 (11%)

Query: 867  ERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAA 926
            E    S+  A +AP++ PAP     TAA  T +A T      +A P   AA   P+A   
Sbjct: 143  ENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQ 200

Query: 927  PSPATAA---ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPA 983
              P+++A    TAA  +P A    P ++S       AP   +A     AP + +  P   
Sbjct: 201  APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT--PAPLSSSAPPETT 258

Query: 984  LVPVPAPAA-----AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPH 1038
             VP P P+A     + ASAP +T A    P+ A TPAP  +P  A  E  A+P T P   
Sbjct: 259  AVP-PTPSATTLDPSSASAPPETTAAPPTPS-ATTPAPPSSP--APQETTAAPITTPNS- 313

Query: 1039 RLSIPSLTCNPDKTDGPVFH-------SNTLERKTPIQILGQEPDAEMVEYL 1083
              S  +L  +  +T     H       + T   K P    GQ   +  + Y+
Sbjct: 314  --SPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYM 363



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 15/204 (7%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            P TPS   P+ P  SA  +T +   +      T++  +++  P +  AP    AT  A  
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSAT--TQAPPSSSAPPETTAAPPTPPATTPAPP 226

Query: 898  ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
            +++A   TT  AA P   A   AP +++AP P T   TA   +P+A    P++AS     
Sbjct: 227  SSSAPPETT--AAPPTPSATTPAPLSSSAP-PET---TAVPPTPSATTLDPSSASAPPET 280

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPT 1017
              AP    +A     P++PAP    A     AP     S+P      TS  + APT   T
Sbjct: 281  TAAP-PTPSATTPAPPSSPAPQETTA-----APITTPNSSPTTLAPDTSETSAAPT-HQT 333

Query: 1018 PTPAVAQAEVPASPATGPGPHRLS 1041
             T    Q      P + PG +++S
Sbjct: 334  TTSVTTQTTTTKQPTSAPGQNKIS 357



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 51/183 (27%), Positives = 71/183 (38%), Gaps = 8/183 (4%)

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            SV  P A+         T      T +++      +++    A   SPA    TAA  +P
Sbjct: 113  SVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTP 172

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP---VPAPALVPVPAPAAAQASAP 998
            +A    P ++S       AP   +A   Q  P++ AP     AP   P   PA   +SAP
Sbjct: 173  SATTPAPPSSSAPPETTAAPPTPSATT-QAPPSSSAPPETTAAPPTPPATTPAPPSSSAP 231

Query: 999  AQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFH 1058
             +T   T+AP       P P  + A  E  A P T P    L   S +  P+ T  P   
Sbjct: 232  PET---TAAPPTPSATTPAPLSSSAPPETTAVPPT-PSATTLDPSSASAPPETTAAPPTP 287

Query: 1059 SNT 1061
            S T
Sbjct: 288  SAT 290



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 13/183 (7%)

Query: 882  SVPAPVAAAATAA-AITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVS 940
            SV  P   A T   ++T  +A+   T +         A   ++    + +++ AT A V+
Sbjct: 99   SVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN 158

Query: 941  PAAAGQIPAAASVASAAAVAPSAAAA----AAVQVAPAAPAPVPAPALVPVPAPAAAQAS 996
              A     AA    SA   AP +++A     A    P+A    P  +  P P   AA  +
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP-PETTAAPPT 217

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIP----SLTCNPDKT 1052
             PA T AP S+ A   T A  PTP+   A  PA  ++   P   ++P    + T +P   
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPS---ATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 1053 DGP 1055
              P
Sbjct: 275  SAP 277



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 40/160 (25%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV 959
            ++ +  T+VA   +      + +      P        A + ++   +  ++SVA+ A V
Sbjct: 98   SSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPV 157

Query: 960  -APSAAAAAAVQVAPAAPAPVPAPALVP-----VPAPAAAQASAPAQTQAPTSAPAVAPT 1013
             +P+     A    P+A  P P  +  P      P   +A   AP  + AP    A  PT
Sbjct: 158  NSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 1014 P---APTPTPAVAQAEVPASP----ATGPGPHRLSIPSLT 1046
            P    P P  + A  E  A+P    AT P P   S P  T
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 69/232 (29%), Positives = 98/232 (42%), Gaps = 26/232 (11%)

Query: 867  ERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAA 926
            E    S+  A +AP++ PAP     TAA  T +A T      +A P   AA   P+A   
Sbjct: 143  ENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQ 200

Query: 927  PSPATAA---ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPA 983
              P+++A    TAA  +P A    P ++S       AP   +A     AP + +  P   
Sbjct: 201  APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT--PAPLSSSAPPETT 258

Query: 984  LVPVPAPAA-----AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPH 1038
             VP P P+A     + ASAP +T A    P+ A TPAP  +P  A  E  A+P T P   
Sbjct: 259  AVP-PTPSATTLDPSSASAPPETTAAPPTPS-ATTPAPPSSP--APQETTAAPITTPNS- 313

Query: 1039 RLSIPSLTCNPDKTDGPVFH-------SNTLERKTPIQILGQEPDAEMVEYL 1083
              S  +L  +  +T     H       + T   K P    GQ   +  + Y+
Sbjct: 314  --SPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYM 363



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 15/204 (7%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            P TPS   P+ P  SA  +T +   +      T++  +++  P +  AP    AT  A  
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSAT--TQAPPSSSAPPETTAAPPTPPATTPAPP 226

Query: 898  ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
            +++A   TT  AA P   A   AP +++AP P T   TA   +P+A    P++AS     
Sbjct: 227  SSSAPPETT--AAPPTPSATTPAPLSSSAP-PET---TAVPPTPSATTLDPSSASAPPET 280

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPT 1017
              AP    +A     P++PAP    A     AP     S+P      TS  + APT   T
Sbjct: 281  TAAP-PTPSATTPAPPSSPAPQETTA-----APITTPNSSPTTLAPDTSETSAAPT-HQT 333

Query: 1018 PTPAVAQAEVPASPATGPGPHRLS 1041
             T    Q      P + PG +++S
Sbjct: 334  TTSVTTQTTTTKQPTSAPGQNKIS 357



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 51/183 (27%), Positives = 71/183 (38%), Gaps = 8/183 (4%)

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            SV  P A+         T      T +++      +++    A   SPA    TAA  +P
Sbjct: 113  SVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTP 172

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP---VPAPALVPVPAPAAAQASAP 998
            +A    P ++S       AP   +A   Q  P++ AP     AP   P   PA   +SAP
Sbjct: 173  SATTPAPPSSSAPPETTAAPPTPSATT-QAPPSSSAPPETTAAPPTPPATTPAPPSSSAP 231

Query: 999  AQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFH 1058
             +T   T+AP       P P  + A  E  A P T P    L   S +  P+ T  P   
Sbjct: 232  PET---TAAPPTPSATTPAPLSSSAPPETTAVPPT-PSATTLDPSSASAPPETTAAPPTP 287

Query: 1059 SNT 1061
            S T
Sbjct: 288  SAT 290



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 13/183 (7%)

Query: 882  SVPAPVAAAATAA-AITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVS 940
            SV  P   A T   ++T  +A+   T +         A   ++    + +++ AT A V+
Sbjct: 99   SVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN 158

Query: 941  PAAAGQIPAAASVASAAAVAPSAAAA----AAVQVAPAAPAPVPAPALVPVPAPAAAQAS 996
              A     AA    SA   AP +++A     A    P+A    P  +  P P   AA  +
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP-PETTAAPPT 217

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIP----SLTCNPDKT 1052
             PA T AP S+ A   T A  PTP+   A  PA  ++   P   ++P    + T +P   
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPS---ATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 1053 DGP 1055
              P
Sbjct: 275  SAP 277



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 40/160 (25%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV 959
            ++ +  T+VA   +      + +      P        A + ++   +  ++SVA+ A V
Sbjct: 98   SSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPV 157

Query: 960  -APSAAAAAAVQVAPAAPAPVPAPALVP-----VPAPAAAQASAPAQTQAPTSAPAVAPT 1013
             +P+     A    P+A  P P  +  P      P   +A   AP  + AP    A  PT
Sbjct: 158  NSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 1014 P---APTPTPAVAQAEVPASP----ATGPGPHRLSIPSLT 1046
            P    P P  + A  E  A+P    AT P P   S P  T
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 69/232 (29%), Positives = 98/232 (42%), Gaps = 26/232 (11%)

Query: 867  ERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAA 926
            E    S+  A +AP++ PAP     TAA  T +A T      +A P   AA   P+A   
Sbjct: 143  ENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQ 200

Query: 927  PSPATAA---ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPA 983
              P+++A    TAA  +P A    P ++S       AP   +A     AP + +  P   
Sbjct: 201  APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT--PAPLSSSAPPETT 258

Query: 984  LVPVPAPAA-----AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPH 1038
             VP P P+A     + ASAP +T A    P+ A TPAP  +P  A  E  A+P T P   
Sbjct: 259  AVP-PTPSATTLDPSSASAPPETTAAPPTPS-ATTPAPPSSP--APQETTAAPITTPNS- 313

Query: 1039 RLSIPSLTCNPDKTDGPVFH-------SNTLERKTPIQILGQEPDAEMVEYL 1083
              S  +L  +  +T     H       + T   K P    GQ   +  + Y+
Sbjct: 314  --SPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYM 363



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 15/204 (7%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            P TPS   P+ P  SA  +T +   +      T++  +++  P +  AP    AT  A  
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSAT--TQAPPSSSAPPETTAAPPTPPATTPAPP 226

Query: 898  ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
            +++A   TT  AA P   A   AP +++AP P T   TA   +P+A    P++AS     
Sbjct: 227  SSSAPPETT--AAPPTPSATTPAPLSSSAP-PET---TAVPPTPSATTLDPSSASAPPET 280

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPT 1017
              AP    +A     P++PAP    A     AP     S+P      TS  + APT   T
Sbjct: 281  TAAP-PTPSATTPAPPSSPAPQETTA-----APITTPNSSPTTLAPDTSETSAAPT-HQT 333

Query: 1018 PTPAVAQAEVPASPATGPGPHRLS 1041
             T    Q      P + PG +++S
Sbjct: 334  TTSVTTQTTTTKQPTSAPGQNKIS 357



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 51/183 (27%), Positives = 71/183 (38%), Gaps = 8/183 (4%)

Query: 882  SVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
            SV  P A+         T      T +++      +++    A   SPA    TAA  +P
Sbjct: 113  SVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTP 172

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP---VPAPALVPVPAPAAAQASAP 998
            +A    P ++S       AP   +A   Q  P++ AP     AP   P   PA   +SAP
Sbjct: 173  SATTPAPPSSSAPPETTAAPPTPSATT-QAPPSSSAPPETTAAPPTPPATTPAPPSSSAP 231

Query: 999  AQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFH 1058
             +T   T+AP       P P  + A  E  A P T P    L   S +  P+ T  P   
Sbjct: 232  PET---TAAPPTPSATTPAPLSSSAPPETTAVPPT-PSATTLDPSSASAPPETTAAPPTP 287

Query: 1059 SNT 1061
            S T
Sbjct: 288  SAT 290



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 13/183 (7%)

Query: 882  SVPAPVAAAATAA-AITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVS 940
            SV  P   A T   ++T  +A+   T +         A   ++    + +++ AT A V+
Sbjct: 99   SVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN 158

Query: 941  PAAAGQIPAAASVASAAAVAPSAAAA----AAVQVAPAAPAPVPAPALVPVPAPAAAQAS 996
              A     AA    SA   AP +++A     A    P+A    P  +  P P   AA  +
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAP-PETTAAPPT 217

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIP----SLTCNPDKT 1052
             PA T AP S+ A   T A  PTP+   A  PA  ++   P   ++P    + T +P   
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPS---ATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 1053 DGP 1055
              P
Sbjct: 275  SAP 277



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 40/160 (25%), Positives = 62/160 (38%), Gaps = 13/160 (8%)

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV 959
            ++ +  T+VA   +      + +      P        A + ++   +  ++SVA+ A V
Sbjct: 98   SSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPV 157

Query: 960  -APSAAAAAAVQVAPAAPAPVPAPALVP-----VPAPAAAQASAPAQTQAPTSAPAVAPT 1013
             +P+     A    P+A  P P  +  P      P   +A   AP  + AP    A  PT
Sbjct: 158  NSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 1014 P---APTPTPAVAQAEVPASP----ATGPGPHRLSIPSLT 1046
            P    P P  + A  E  A+P    AT P P   S P  T
Sbjct: 218  PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPET 257


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 103/407 (25%), Positives = 176/407 (43%), Gaps = 85/407 (20%)

Query: 407 YSAMPRAQPSS-ASYQPVPADPFAI---VSRAQQMVEILSDENRNLRQELEGCYEKVARL 462
           +S   R+Q SS A  + V  +  A+   V+ A   +  L  E R L ++LE   EK  R 
Sbjct: 571 WSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERA 630

Query: 463 QKVETEIQRVSEAYENLV-KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETA--- 518
           +K+E E+QR+ E    L  K +S   A EK     LE E + +   NR LR+ L+T    
Sbjct: 631 EKLERELQRLQEENGRLARKVTSLETATEKV--EALEHESQGLQLENRTLRKSLDTLQNV 688

Query: 519 ----------NKQL------AEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATAR 562
                     NKQL        +  E    T   ++Q+  +N++ +REKE+L   +   +
Sbjct: 689 SLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLK 748

Query: 563 STNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQ 622
           +  +   R +E+  Q++S   A+ ++L++ L+       K + ++  L +L+A       
Sbjct: 749 ALGKKSER-LELSYQSVS---AENLRLQQSLESSS---HKTQTLESELGELEAE------ 795

Query: 623 LEHRLRTRLERELESLRI--QQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTK 680
                R  L R+LE+LR+   Q +G  +     E   A L     EK++++L  EA    
Sbjct: 796 -----RQALRRDLEALRLANAQLEGAEKDRKALEQEVAQL-----EKDKKLLEKEAKRL- 844

Query: 681 WEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKR 740
           W+Q  L++ V+     D+ A ++A                      ++KE   +     R
Sbjct: 845 WQQVELKDAVLD----DSTAKLSA----------------------VEKESRALDKELAR 878

Query: 741 CLDMEGRIKTLH-------AQIIEKDAMIKVLQQRSRKEPSKTEQLS 780
           C D  G++K L         Q+      +  L++    E  K++QLS
Sbjct: 879 CRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLS 925



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 65/270 (24%), Positives = 121/270 (44%), Gaps = 46/270 (17%)

Query: 435 QQMVEILSDEN--RNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEK- 491
           Q+ +++ +D    R  R EL+   EK  R++++E E+ R  E   ++    ++ E L + 
Sbjct: 296 QENIQLAADARSARAYRDELDSLREKANRVERLELELTRCKEKLHDVDFYKARMEELRED 355

Query: 492 -----AMRNKLEGEIRRMHDFNRDLRERLETANKQLAEK--EYEGSEDT-RKTISQLFAK 543
                  +  LE ++         + E LE  N QL  K  + E   DT +K I +L  +
Sbjct: 356 NIILIETKAMLEEQLTAARARGDKVHE-LEKENLQLKSKLHDLELDRDTDKKRIEELLEE 414

Query: 544 N-------KESQREKEKLEAELATARSTNEDQRRHIEIRDQALSN--------AQAKVVK 588
           N       K+S  E   L  EL       E   ++ ++ D +  +        A ++++K
Sbjct: 415 NMVLEIAQKQSMNESAHLGWEL-------EQLSKNADLSDASRKSFVFELNECASSRILK 467

Query: 589 LEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQ 648
           LE+E +  Q  +  +      L +    C + E+  H+L  ++E+ L++   +++Q N  
Sbjct: 468 LEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKKIEK-LQTQLEREKQSNQD 526

Query: 649 PTNVSEYNAAALMELLREKEERILALEADM 678
              +SE       EL+REKE+    L++DM
Sbjct: 527 LETLSE-------ELIREKEQ----LQSDM 545



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 67/270 (24%), Positives = 120/270 (44%), Gaps = 47/270 (17%)

Query: 444 ENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSK-REALEKAMRNK--LEGE 500
           EN+ L +E E   + V  L+ +  + +R+  +Y+++   + + +++LE +      LE E
Sbjct: 729 ENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESE 788

Query: 501 IRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELAT 560
           +  +    + LR  LE    +LA  + EG+E  RK + Q  A     Q EK+K   E   
Sbjct: 789 LGELEAERQALRRDLEAL--RLANAQLEGAEKDRKALEQEVA-----QLEKDKKLLEKEA 841

Query: 561 ARSTNEDQRRHIEIRDQALSNAQAKVVKLEEEL---------------KKKQVYVDKVEK 605
            R   +     +E++D  L ++ AK+  +E+E                K K++  D  + 
Sbjct: 842 KRLWQQ-----VELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDL 896

Query: 606 MQQALVQLQAACEKREQLE-HRLRT--------RLERELESLRIQQR-------QGNCQP 649
            +Q  V  +     RE L   +L++        +L +ELE + + +         G+   
Sbjct: 897 TKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTK 956

Query: 650 TNVSE-YNAAALMELLREKEERILALEADM 678
             + E  N +AL   L  KEE+I+ LEA M
Sbjct: 957 YKILEGRNESALKTTLAMKEEKIVLLEAQM 986



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 92/375 (24%), Positives = 152/375 (40%), Gaps = 77/375 (20%)

Query: 457  EKVARLQK----VETEIQRVSEAYEN----LVKSSSKREALEKAMRNKLEGEIRRMHDFN 508
            ++VA+L+K    +E E +R+ +  E     L  S++K  A+EK  R  L+ E+ R  D  
Sbjct: 825  QEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESR-ALDKELARCRDAA 883

Query: 509  RDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR---EKEKLEAELATARSTN 565
              L+E LE  N+ L ++    +         L  +  +SQ+   E +KL  EL       
Sbjct: 884  GKLKE-LEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNR 942

Query: 566  EDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEH 625
            E   +     D + S+ + K+++   E   K     K EK+     Q++       QLE 
Sbjct: 943  ELLLQE----DDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLES 998

Query: 626  RLRTRLERELESLRIQQRQGNCQPTNVSEYNAA-------------------ALMELLRE 666
             L+  L++E E+LR  Q QG  Q    S  + A                   A MELLR 
Sbjct: 999  ELQ-MLKKECETLR--QNQGEGQHLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELLRV 1055

Query: 667  KEERI--------LALEADMTKWEQKYLE-ENV-----------MRHFALDAAATVAAQR 706
            K+  I        L  E  + K + ++LE +NV              F  +   T+  Q 
Sbjct: 1056 KDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQTQT 1115

Query: 707  DTTVISHSPNTSYDTALEAR-----------------IQKEEEEILMANKRCLDMEGRIK 749
                + +S  +S   AL A+                 +Q+++E++  A +  L     + 
Sbjct: 1116 AKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLG 1175

Query: 750  TLH-AQIIEKDAMIK 763
            TLH  Q  E +A+I+
Sbjct: 1176 TLHERQSAEYEALIR 1190



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 51/271 (18%), Positives = 112/271 (41%), Gaps = 22/271 (8%)

Query: 370  SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA 429
            SQ      Q    Q HH     + +  Q+ Q+Q   AY A+ +      +     +  + 
Sbjct: 1127 SQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYE 1186

Query: 430  IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEI---QRVSEAYENLVKSSSKR 486
             + R    ++ L   +RNL  E +   E+   + K + E+   ++V       ++   + 
Sbjct: 1187 ALIRQHSCLKTL---HRNLELEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRT 1243

Query: 487  EALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKE 546
             AL      +L GE+ R++  +  L+   E  +    E +     + +  +++  A+  E
Sbjct: 1244 NALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELK-TSLNNAQLELNRWQARFDE 1302

Query: 547  SQREKEKLEAE----------LATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKK 596
             + + + ++            L+  +   E++  H+  + Q LS  Q   + LE+ ++ K
Sbjct: 1303 LKEQHQTMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLS--QQNQMLLEQNMENK 1360

Query: 597  QVYVDKVEKMQQALVQLQAACEKREQLEHRL 627
            + Y    E+ +Q + +L A    +E+LE ++
Sbjct: 1361 EQY---HEEQKQYIDKLNALRRHKEKLEEKI 1388



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 20/134 (14%)

Query: 920  APAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPV 979
            AP      +P   +ATA A++ A AG   AA S +++  +  S AAA A +  P AP   
Sbjct: 1889 APPKEERLAPLHQSATAPAIATAGAG-AAAAGSGSNSQLLHFSPAAAPAARTKPKAP--- 1944

Query: 980  PAPALVPVPAPAAAQASAPAQTQAP-----TSAPAVAPTPAPTPTPAVAQA--------- 1025
            P    V    P  A  S       P        PA +P  +P   P + +A         
Sbjct: 1945 PRSGEVATITPVRAGLSLSEGDGVPGQGCSEGLPAKSPGRSPDLAPHLGRALEDCSRGSV 2004

Query: 1026 --EVPASPATGPGP 1037
                PASP  G  P
Sbjct: 2005 SKSSPASPEPGGDP 2018



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 36/148 (24%), Positives = 47/148 (31%), Gaps = 18/148 (12%)

Query: 938  AVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASA 997
            A  P A G  P   +    A +  +  A      AP +      P     P     +A A
Sbjct: 1703 ASDPPAIGGQPGPPAKKEGAKMPTNFVAPTVKMAAPTSEGRPLKPGQYVKPNFRLTEAEA 1762

Query: 998  PA-----QTQAPTSAPAVAPTPAPTPTPAVAQAEVPAS-------------PATGPGPHR 1039
            P      Q Q P S     P  AP P  + A A   AS              A+GP   +
Sbjct: 1763 PPSVAPRQAQPPQSLSLGRPRQAPVPPASHAPASRSASLSRAFSLASADLLRASGPEACK 1822

Query: 1040 LSIPSLTCNPDKTDGPVFHSNTLERKTP 1067
               P     P+   G    S+TL+   P
Sbjct: 1823 QESPQKLGAPEALGGRETGSHTLQSPAP 1850


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 88/403 (21%), Positives = 172/403 (42%), Gaps = 36/403 (8%)

Query: 376 QQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
           Q++++Q ++       +++Q+++ QQQ       + R Q                  R +
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE---------------RRE 316

Query: 436 QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
           Q  E    + R  +QE E   +++ R Q+   E Q   E  E   +   +RE  E+    
Sbjct: 317 QQEERREQQERREQQE-ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375

Query: 496 KL--EGEIRRMHDFNRD--LRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREK 551
           +L  E ++RR     R+  LR   +   +Q   +E +   + +    Q   + +E +R +
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435

Query: 552 EKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALV 611
           +K E E    R   E + R   ++       + +  + E+E +K+Q+  D+ E+ ++  +
Sbjct: 436 QKHEQERREQRLKREQEERRDWLK------REEETERHEQERRKQQLKRDQEEERRERWL 489

Query: 612 QLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEER- 670
           +L+   E+REQ E R   +L RE E  R +QR    +     +    +  +L RE+EER 
Sbjct: 490 KLEEE-ERREQQERR-EQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQLRREQEERR 546

Query: 671 -ILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQK 729
             L    +  + EQ+  E+ + R    +       +R+            +  LE R+++
Sbjct: 547 EQLLKREEEKRLEQERREQRLKRE--QEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604

Query: 730 EEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKE 772
           EE E L   +R    E R+K    +   +  ++K  +Q  R++
Sbjct: 605 EEVERLEQEER---REQRLKREEPEEERRQQLLKSEEQEERRQ 644



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 93/414 (22%), Positives = 173/414 (41%), Gaps = 40/414 (9%)

Query: 363 QGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQP 422
           Q +  R  Q    QQ+++++QQ       +++QQ + +Q+       + R Q      Q 
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376

Query: 423 VPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKS 482
                   + R QQ+        + LR+E +   E+  R ++     Q++    +   + 
Sbjct: 377 --------LRREQQL-----RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423

Query: 483 SSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFA 542
             +RE  E+    K E E RR     R+  ER +   +   E+E E  E  R+   Q   
Sbjct: 424 QLRREQEEERHEQKHEQE-RREQRLKREQEERRDWLKR---EEETERHEQERR--KQQLK 477

Query: 543 KNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDK 602
           +++E +R +  L+ E        E++R   E R+Q L   Q +  + E+ LK++    ++
Sbjct: 478 RDQEEERRERWLKLE-------EEERREQQERREQQLRREQEE--RREQRLKRQ----EE 524

Query: 603 VEKMQQAL---VQLQAACEKREQ--LEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNA 657
            E++QQ L    QL+   E+R +  L+     RLE+E    R+++ Q   +   +     
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584

Query: 658 AALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNT 717
                L RE+EER   LE  + + E + LE+   R   L        +R   + S     
Sbjct: 585 RRQQRLKREQEER---LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641

Query: 718 SYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRK 771
                L    Q+  E+ L   +    +E R+K  H +   +  + +  Q+++R+
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 63/329 (19%), Positives = 137/329 (41%), Gaps = 14/329 (4%)

Query: 371  QPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAI 430
            + GL + Q++++ Q        + Q ++ +++      A P  Q      Q +  +    
Sbjct: 853  EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912

Query: 431  VSRAQQMVEILSDENRNLRQE--LEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREA 488
            + R ++      ++ R  R+E  L+   E++ R ++ +   Q     Y    K   K E 
Sbjct: 913  LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972

Query: 489  L-----EKAMRNKLEGEIRRMHDFNRD----LRERLETANKQLAEKEYEGSEDTRKTISQ 539
            L     EK  R + E + R   +  ++    LRE  E   +Q  E++Y   ++ ++   Q
Sbjct: 973  LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032

Query: 540  LFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVY 599
            L  + +E +R +E+            E+++   E R+        +  + EEEL++++  
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092

Query: 600  VDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAA 659
            + + E  ++   + +  C + E+L+      L  E E  R Q+ +   +     +     
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE- 1151

Query: 660  LMELLREKEERILALEADMTKWEQKYLEE 688
              +LLRE+ E+    E +    E++ L++
Sbjct: 1152 --QLLREEPEKRRRQELERQYREEEELQQ 1178



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 99/458 (21%), Positives = 183/458 (39%), Gaps = 74/458 (16%)

Query: 374  LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSR 433
            L ++++++++Q     + ++ + QQ ++Q         R Q     Y+            
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE--------EE 1055

Query: 434  AQQMVEILSDENRNLR--QELEGCYEKVARLQKVETEI-------------QRVSEAYEN 478
             QQ  E L  E R  R  QELE  Y K   LQ+ E ++             +R     E 
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115

Query: 479  LVKSSSK--REALEKAMRNKLEGEIRRMHDFNRD----LRERLETANKQLAEKEYEGSED 532
            L +   +  RE  EK  R +LE + R   +  ++    LRE  E   +Q  E++Y   E+
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175

Query: 533  TRKTISQLFAKNKESQ--------REKEKLEAELATARSTNEDQRRHIE----------I 574
             ++   QL  + +E +        RE+E+L+ +    R  +EDQR  ++          +
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235

Query: 575  RDQAL-----SNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRT 629
            RD  +      N Q + ++ + +L+ +Q   D    +Q  L + Q    ++E+   + R 
Sbjct: 1236 RDNKVYCKGRENEQFRQLE-DSQLRDRQSQQD----LQHLLGEQQERDREQERRRWQQRD 1290

Query: 630  RLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYL--- 686
            R   E E L  ++++   +    S+     L E   E+EE+    E D    E++ L   
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQE 1347

Query: 687  -EENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANK----RC 741
             EE  +R    D        R      H          E R++++E E     +    RC
Sbjct: 1348 REEQPLRRQERDRKFREEELR------HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401

Query: 742  LDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQL 779
             + E +++    +   ++      Q+R RK   + +Q+
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 68/309 (22%), Positives = 137/309 (44%), Gaps = 35/309 (11%)

Query: 349 LPRPQQHFLPNQAHQGDHYRLSQPGLSQQQ--QQQQQQHHHHHHHQQQQQQQPQQQPGEA 406
           L R QQ     Q  +    R  Q    +QQ  ++Q+++ H   H Q++++Q+ +++  E 
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454

Query: 407 YSAMPRAQPSSASYQPVPADPFAI---VSRAQQMVEILSDENRN--------LRQELEGC 455
              + R + +    Q              R ++ +++  +E R         LR+E E  
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514

Query: 456 YEKVARLQKVETEIQRVSEAYENLVKSSSKR--EALEKAMRNKLEGEIRRMHDFNRDLRE 513
            E+  + Q+ E  +Q+   + + L +   +R  + L++    +LE E RR     R+  E
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE-RREQRLKREQEE 573

Query: 514 RLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIE 573
           R +   K+  E+  +  +  ++   +   K +E +R +++   E    R   E++RR   
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633

Query: 574 IRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLER 633
           ++ +            +EE +++Q+  ++ E+ +Q L        KRE+ E RL  RL+R
Sbjct: 634 LKSEE-----------QEERRQQQLRREQQERREQRL--------KREEEEERLEQRLKR 674

Query: 634 ELESLRIQQ 642
           E E  R +Q
Sbjct: 675 EHEEERREQ 683



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 70/328 (21%), Positives = 141/328 (42%), Gaps = 16/328 (4%)

Query: 371 QPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAY--SAMPRAQPSSASYQPVPADPF 428
           +PG  ++Q++Q+Q+       +Q ++Q+  +Q         + R +      +   A+  
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191

Query: 429 AIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAY-ENLVKSSSKRE 487
            + S      E   DE +  R+EL     K  R +K +   +R    + E   K   KRE
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRK-GREEKQQQRRERQDRVFQEEEEKEWRKRE 250

Query: 488 ALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTI---SQLFAKN 544
            + +    KL+ E  +     ++  E+L    +Q   +E +  E  ++ +    QL  K 
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310

Query: 545 KESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVE 604
           +E +RE+++   E    R   E++R     R+Q     Q    + EEE +++Q+  ++ E
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370

Query: 605 KMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELL 664
           + ++  ++ +    + +QL    + R E++L   +  +R+   +     E       +L 
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----REQQLRREQQLR 426

Query: 665 REKEERILALEADMTKWEQKYLEENVMR 692
           RE+EE     E    K EQ+  E+ + R
Sbjct: 427 REQEE-----ERHEQKHEQERREQRLKR 449



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 61/328 (18%), Positives = 144/328 (43%), Gaps = 26/328 (7%)

Query: 376 QQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
           ++QQ++++Q       ++++Q+  +Q+  E      R++      Q    +   ++ R +
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ--LLKREE 554

Query: 436 QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
           +         + L++E E   +++ + ++ E   QR+    E  ++   KRE +E+  + 
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREE-ERRQQRLKREQEERLEQRLKREEVERLEQE 613

Query: 496 KLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLE 555
           +   +  +  +   + R++L  + +Q   ++ +   + ++   Q   + +E +R +++L+
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673

Query: 556 AELATARSTNEDQRRHIEIRDQALSNAQAKVV--------KLEEELKKKQVYVDKVEKMQ 607
            E       +E++RR  E+ ++    A+ ++         +LE E   +Q  V    + Q
Sbjct: 674 RE-------HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726

Query: 608 QALVQLQAACEKREQLEHRLR-------TRLERELESLRIQQRQGNCQPTNVSEYNAAAL 660
           +   + Q   EKR + E  L+        R ++E E  R    Q   +  +       + 
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786

Query: 661 MELLREKEERILALEADMTKWEQKYLEE 688
              LRE+ ER L  E +  + EQ++L E
Sbjct: 787 RPPLREQRERQLRAE-ERQQREQRFLPE 813



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 90/471 (19%), Positives = 190/471 (40%), Gaps = 61/471 (12%)

Query: 353  QQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAY-SAMP 411
            +Q  L  +  +    RL +    ++ +Q+ ++ H     +Q+  ++ Q+Q  E   S +P
Sbjct: 643  RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702

Query: 412  RAQPSSASYQPVPADPFAIVSR-----AQQMVEILSDENRNLRQELEGCYEKVARLQKVE 466
            + Q    S     A    + SR      Q+  +   ++ R    EL+   E+ A  Q+ E
Sbjct: 703  KWQWQLES--EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760

Query: 467  TEIQR-------VSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETAN 519
             E +R         E  E   +  S R  L +    +L  E R+  +  R L E  E   
Sbjct: 761  EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE-QRFLPEEEEKEQ 819

Query: 520  KQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQ-- 577
            ++   +E E      +   QL  + +  Q ++E+   +    R  +++QRR  + R Q  
Sbjct: 820  RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE 879

Query: 578  -----------ALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHR 626
                       A    Q ++ K ++ L++++  + + E+ ++   + +    + EQL+  
Sbjct: 880  EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939

Query: 627  LRTRLERELESLRIQQRQGNCQPTNVSEYNAAALM-------------------ELLREK 667
                L  E E  R Q+R+   +     +     L+                   E L+++
Sbjct: 940  EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999

Query: 668  EERILALEADMTK---WEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALE 724
            EE++L  E +  +   WE++Y +++ ++    +    +  +R+   +        +   E
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQ---EEEQLLREEREKRRLQERERQYRE---E 1053

Query: 725  ARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSK 775
              +Q+EEE++L   +       R + L  Q  +++ + +  +Q  R+EP K
Sbjct: 1054 EELQQEEEQLLGEERE----TRRRQELERQYRKEEELQQEEEQLLREEPEK 1100



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 68/373 (18%), Positives = 156/373 (41%), Gaps = 58/373 (15%)

Query: 351  RPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAM 410
            R +Q+    +  Q +   L +   ++++Q+ ++Q+      QQ+++Q  +++P +     
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105

Query: 411  PRAQPSSASYQPVPADPFAIVSRAQQMVEILSDE-NRNLRQELEGCYEKVARLQKVETEI 469
               Q                    Q+  ++L +E  +  RQELE  Y +   +Q+ E ++
Sbjct: 1106 RERQCREEE------------ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153

Query: 470  ----------QRVSEAYENLVKSSSKREAL----EKAMRNKLEGEIRRMHDFNRDLRERL 515
                      Q +   Y    +   + E L    ++  R + E + R   +  R  R++ 
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213

Query: 516  ETANKQLAEKEYEGSEDTRKTI--SQLFAKNKESQREKEKLEAELATARS---------- 563
                 Q ++ +++   +    +  ++++ K +E+++ ++  +++L   +S          
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273

Query: 564  ----TNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEK 619
                  E +RR  + RD+     +    +LE E +K+    D+  + ++ L++     E+
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEE----QLEREEQKEAKRRDRKSQEEKQLLR-----EE 1324

Query: 620  REQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADM- 678
            RE+   R  T  +   E   +Q+R+   QP    E +     E LR +E+    LE +  
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREE--QPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382

Query: 679  ---TKWEQKYLEE 688
                + E+K+L+E
Sbjct: 1383 LRRQERERKFLKE 1395



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 67/322 (20%), Positives = 132/322 (40%), Gaps = 17/322 (5%)

Query: 374  LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSR 433
            L ++QQ +Q++H      +Q  Q++ +QQ         R +      Q +         R
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQ----LHRQERDRKFLEEEQQLRRQERDRKFR 1504

Query: 434  AQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAM 493
             Q   E+ S E      E E    +  R +K   E Q++        +   +     +  
Sbjct: 1505 EQ---ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561

Query: 494  RNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEK 553
            + + E E +++    RD + RLE    +  E+E +  ED ++   Q   +    +R+++ 
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621

Query: 554  LEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQL 613
             E E        E+Q+ H + RD+     + ++ + E E   +Q+  D+  K ++    L
Sbjct: 1622 REDE--QLLQEREEQQLHRQERDRKFLEEEPQLRRQERE---QQLRHDRDRKFREEEQLL 1676

Query: 614  QAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILA 673
            Q   E++ + + R R +   E + LR Q+R+         +     L    RE+E+    
Sbjct: 1677 QEGEEQQLRRQERDR-KFREEEQQLRRQERERKFLQEE-QQLRRQELERKFREEEQLRQE 1734

Query: 674  LEADMTKWEQKY---LEENVMR 692
             E +  + +++Y   LEE  +R
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLR 1756



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 65/331 (19%), Positives = 146/331 (44%), Gaps = 29/331 (8%)

Query: 367  YRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPAD 426
            +RL +  + +Q+Q+++         +Q+ QQQ +Q+    +    +        Q     
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ----- 1635

Query: 427  PFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKR 486
                + R ++  + L +E +  RQE E    +  R +K   E Q + E  E  +    +R
Sbjct: 1636 ----LHRQERDRKFLEEEPQLRRQEREQ-QLRHDRDRKFREEEQLLQEGEEQQL----RR 1686

Query: 487  EALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKE 546
            +  ++  R + E ++RR     + L+E  +   ++L E+++   E  R+   Q   + + 
Sbjct: 1687 QERDRKFREE-EQQLRRQERERKFLQEEQQLRRQEL-ERKFREEEQLRQETEQ--EQLRR 1742

Query: 547  SQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKM 606
             +R ++ LE E    R   E+Q+   + RD+     +    +L +E +++Q+   + ++ 
Sbjct: 1743 QERYRKILEEE--QLRPEREEQQLRRQERDRKFREEE----QLRQEREEQQLRSQESDRK 1796

Query: 607  QQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAA---ALMEL 663
             +   QL+   E+++    +   +   E E L++++++   +     +Y A    A  E 
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856

Query: 664  LREKEERILALEADMTKW--EQKYLEENVMR 692
             R +E+ +   E    +   E+K  EE++ R
Sbjct: 1857 SRREEQELWQEEEQKRRQERERKLREEHIRR 1887



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/316 (18%), Positives = 134/316 (42%), Gaps = 16/316 (5%)

Query: 376  QQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
            Q++++Q+++  +    + Q+Q++ Q+   E   +  + Q        V  +      R  
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247

Query: 436  QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
            +    L D     RQ  +     +   Q+ + E +R    ++   +   + E LE+  + 
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER--RRWQQRDRHFPEEEQLEREEQK 1305

Query: 496  KLEGEIRRMHDFNRDLRE-RLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQRE--KE 552
            + +   R+  +  + LRE R E   +Q  ++++   E   +   +   + +E  R+  +E
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365

Query: 553  KLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQ 612
            +L  +    +   E+QR   + R++     + ++   E E + +Q    K  + +Q L +
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425

Query: 613  LQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERIL 672
             +   + RE+ +   R   ER+      Q RQ   +     E       +LL+E+EE+ L
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE-------QLLQEREEQQL 1478

Query: 673  ALEADMTKWEQKYLEE 688
              +    + ++K+LEE
Sbjct: 1479 HRQ----ERDRKFLEE 1490



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 57/284 (20%), Positives = 119/284 (41%), Gaps = 56/284 (19%)

Query: 362  HQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQ 421
            H  D     +  L Q+ ++QQ +        ++++QQ ++Q  E                
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER--------------- 1707

Query: 422  PVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARL-QKVETEIQRVSEAYENLV 480
                             + L +E +  RQELE  + +  +L Q+ E E  R  E Y  ++
Sbjct: 1708 -----------------KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750

Query: 481  KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQL 540
            +        E+ +R + E +  R  + +R  RE  E   ++  E++    E  RK   + 
Sbjct: 1751 E--------EEQLRPEREEQQLRRQERDRKFREE-EQLRQEREEQQLRSQESDRKFREE- 1800

Query: 541  FAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYV 600
              +    +RE+++L  +    +   E+++  +E ++Q L   + +  + EE+   +    
Sbjct: 1801 --EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ---- 1854

Query: 601  DKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQ 644
            +K  + +Q L Q +   ++R++ E +LR       E +R QQ++
Sbjct: 1855 EKSRREEQELWQ-EEEQKRRQERERKLRE------EHIRRQQKE 1891



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/339 (19%), Positives = 141/339 (41%), Gaps = 30/339 (8%)

Query: 363  QGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQP 422
            Q D +   +  L +++Q++ ++       ++Q  ++ +++         + +      Q 
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347

Query: 423  VPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKS 482
                P     R Q+      +E    +++     E+  RL++ E E + + E  E  ++ 
Sbjct: 1348 REEQPL----RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE--EQQLRC 1401

Query: 483  SSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFA 542
              + + L +    K   E +++    RD + R E    +  E+E +  E+ +    QL  
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ----QLRQ 1457

Query: 543  KNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDK 602
            +     RE+E+L  E        E+Q+ H + RD+     + ++ + E + K ++  +  
Sbjct: 1458 ERHRKFREEEQLLQE-------REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510

Query: 603  VEKMQQALVQLQAACEKREQLEHRLRTR-LERELESLRIQQRQGNCQPTNVSEYNAAALM 661
             E  ++ L       E+ +QL  + R R   +E + LR Q+R    +     ++      
Sbjct: 1511 QEPERKFL-------EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE-- 1561

Query: 662  ELLREKEERILALEADMTKW---EQKYLEENVMRHFALD 697
            +L +E+EE+ L+ +    K+   EQK   +   R F  D
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 47/225 (20%), Positives = 95/225 (42%), Gaps = 22/225 (9%)

Query: 376  QQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
            ++++QQ ++        Q++QQ  +Q+    +    + +  +   Q         + R +
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ---------LRRQE 1744

Query: 436  QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
            +  +IL +E     +E E    +  R +K   E Q   E  E  ++S        +  + 
Sbjct: 1745 RYRKILEEEQLRPERE-EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803

Query: 496  KLEGEIRRMHDFNRDLRERLETANKQLAEKE--YEGSEDTRKTISQLFAKNKESQREKEK 553
            + E E +++    RD + R E    QL E+E       D +    + FA  ++S+RE+++
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863

Query: 554  LEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQV 598
            L  E    R     Q R  ++R++ +   Q      +EE + +QV
Sbjct: 1864 LWQEEEQKRR----QERERKLREEHIRRQQ------KEEQRHRQV 1898



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 65/315 (20%), Positives = 131/315 (41%), Gaps = 29/315 (9%)

Query: 489 LEKAMRNKLEGEIRRMHDFNRDL-RERLETANKQLAEKEYEGSEDTRKTISQLFAKNKES 547
           L++  R + +G+   + D  ++  + R E  ++QL E+  +     R+   +  A+ +E 
Sbjct: 95  LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154

Query: 548 QREKEKLEAELATARS----------TNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQ 597
             ++E+LE      R              ++RR  E + Q+    + +    EE+L++++
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214

Query: 598 VY----VDKVEKMQQALVQLQAACEKREQLEHRLR-TRLERELESLRIQ--QRQGNCQPT 650
           +       + EK QQ   +     ++ E+ E R R T L +E E L+ +  QRQ   Q  
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274

Query: 651 NVSEYNAAALMELLREKEE------RILALEADMTKWEQKYLEENVMRHFALDAAATVAA 704
              +       EL RE++E      R+   +    K E++  E+   R    +       
Sbjct: 275 E-EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333

Query: 705 QRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTL-HAQIIEKDAMIK 763
           +R+  +             + R ++EEE      +R  + E R + L   Q + ++  ++
Sbjct: 334 RREQQLRREQEERREQ---QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390

Query: 764 VLQQRSRKEPSKTEQ 778
             QQ  R++  + EQ
Sbjct: 391 REQQLRREQQLRREQ 405


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
            sapiens]
          Length = 907

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 67/226 (29%), Positives = 93/226 (41%), Gaps = 23/226 (10%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITA 898
            + P+P PP+    +     G    +  +   +E+  +   AP   P P    A  A  +A
Sbjct: 365  AAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAP--EPTPPTTTAEIATASA 422

Query: 899  TAATITTTMVAAAPV-------AVAAAAAPAAA-AAPSPATAAATAAAVSPAAAGQIPAA 950
            +A+T TT     A V       A +   APAA+  A +PAT    AAA+  A +G  P A
Sbjct: 423  SASTTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALD-ACSGNDPFA 481

Query: 951  ASVASAAAV------APSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 1004
             S  SA A       A      +   V P A    P PA  P PAPA A A+A A T A 
Sbjct: 482  PSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVA-AAAAATTAAT 540

Query: 1005 TSAPAVAPTPAPTPTPAVAQAEV-----PASPATGPGPHRLSIPSL 1045
             +A     T A T T A    ++      ++P     P   + PS+
Sbjct: 541  AAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSI 586



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 65/260 (25%), Positives = 103/260 (39%), Gaps = 43/260 (16%)

Query: 834  AEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATA 893
            AE V      +P  T   S+  +T  +  +T   +   +N+ +       P+P++ ++ A
Sbjct: 254  AEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGA-----PSPLSKSSPA 308

Query: 894  AAITATAATITTTMVAAAPV---AVAAAAAPAAAAAP-----------SPATAAATAAAV 939
              +T+  +T   T+  + PV   A A+AA P + + P           S   AAA AA  
Sbjct: 309  TTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPA 368

Query: 940  SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVA-PAAPAPVPAPALVPVPAPAAAQASAP 998
             P  AG   A   +    ++A  ++  +  Q++ P AP P P P      A A+A AS  
Sbjct: 369  PPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTP-PTTTAEIATASASASTT 427

Query: 999  AQTQAPTS-------APAVAPTPAP----------TPTPAVAQAEV-----PASPATGPG 1036
                A T+       A A +P  AP          TPTP  A  +      P +P+ G  
Sbjct: 428  TTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSA 487

Query: 1037 PHRLSIPSLTCNPDKTDGPV 1056
                 +      P +T  PV
Sbjct: 488  EAAPELDLFAMKPPETSVPV 507



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 74/287 (25%), Positives = 101/287 (35%), Gaps = 93/287 (32%)

Query: 838  PSTPSPVPPSTPLLSAHS----KTGSRDCSTQ----------------TERGTESNKTAA 877
            P+TP+PV  +    S +       GS + + +                T   + +    A
Sbjct: 461  PATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPA 520

Query: 878  VAPISVPAPVAAAATAAAITATAATITTTMVAAAPVA----------------VAAAAAP 921
             AP   PA  AAAA   A TA A T TTT  A A  A                VAAA  P
Sbjct: 521  TAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKP 580

Query: 922  AAA------------------------------------AAPSPATAAATAA-------- 937
             AA                                    AAPSPAT A+ A         
Sbjct: 581  DAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVID 640

Query: 938  ----AVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAA 993
                A   +A+   PA+ + +S++A A   A      +AP+     PA   +  P   AA
Sbjct: 641  LFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQPNFEAA 700

Query: 994  QASAPAQTQAPTSAPAV--------APTPAPTPTPAVAQAEVPASPA 1032
              + P+ + + +  P+V         PT AP   PA   + VP SPA
Sbjct: 701  FGTTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPV-SMVPPSPA 746



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 69/251 (27%), Positives = 94/251 (37%), Gaps = 54/251 (21%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAV-----APISVPAPVAAAAT 892
            P  P P PP+T   +A   T S   ST T   T +  TA V     A  + P    AA+ 
Sbjct: 403  PFAPEPTPPTT---TAEIATASASASTTT---TVTAVTAEVDLFGDAFAASPGEAPAASE 456

Query: 893  AAAITATAATITTTMVAA------APVAVAAAAAP--------------------AAAAA 926
             AA  AT   +   + A       AP   +A AAP                    A+ A 
Sbjct: 457  GAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP 516

Query: 927  PSPATAA----ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAP 982
            P PATA     A AAA +   A    A  +  ++AA A +A  A  +        P  A 
Sbjct: 517  PVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAA 576

Query: 983  ALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042
            A  P  AP+    S  A +  P  A   +P P  + T  +   +  A+P+          
Sbjct: 577  APKPDAAPSIDLFSTDAFSSPPQGA---SPVPESSLTADLLSVDAFAAPS---------- 623

Query: 1043 PSLTCNPDKTD 1053
            P+ T +P K D
Sbjct: 624  PATTASPAKVD 634



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 54/222 (24%), Positives = 78/222 (35%), Gaps = 19/222 (8%)

Query: 827  LLGGDYRAEYVPSTPSPVPPSTPLL------SAHSKTGSRDCSTQTER----GTESNKTA 876
            LL G +   ++  +PSPV P+   L      +A   T S   S+  +     G       
Sbjct: 669  LLAG-FGGSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMP 727

Query: 877  AVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATA 936
             +AP   PAPV+    + A+ A+ A + + + ++    V                  A  
Sbjct: 728  TMAPAGQPAPVSMVPPSPAMAASKA-LGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGE 786

Query: 937  AAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQAS 996
              ++  A  Q P  A    +A V PSA    AV    + P    AP+   V  P A    
Sbjct: 787  KKLTGGANWQ-PKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPS---VGQPGAGFGM 842

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPA---SPATGP 1035
             PA T  P           P   P    A VP    SP+  P
Sbjct: 843  PPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTP 884



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 42/170 (24%), Positives = 66/170 (38%), Gaps = 25/170 (14%)

Query: 838 PSTPSPVPPST---PLLSAHSKTGSRDCSTQTERGTESNKT------AAVAPISVPAPVA 888
           P   SPVP S+    LLS  +       +T +    +S+        A  +  S P P +
Sbjct: 598 PQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPAS 657

Query: 889 AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP 948
            AA++++ +A                +A       A +PSP T A     + P       
Sbjct: 658 QAASSSSASADL--------------LAGFGGSFMAPSPSPVTPAQNNL-LQPNFEAAFG 702

Query: 949 AAASVASAAAVAPSAAAAAAVQVAPA-APAPVPAPALVPVPAPAAAQASA 997
              S +S+++  PS        + P  APA  PAP  +  P+PA A + A
Sbjct: 703 TTPSTSSSSSFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKA 752


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 71/381 (18%), Positives = 165/381 (43%), Gaps = 46/381 (12%)

Query: 347 AHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQ----------QQQQQQQHHHHHHHQQQQQ 396
           A L  PQQ       H G   +     L  Q           QQQ+++        Q+ +
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374

Query: 397 QQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCY 456
           ++ Q+Q  +      + +      +      +    + ++  E++ ++   +R++ E  +
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434

Query: 457 EKVARLQKVETEI--------QRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFN 508
           EK  +++++E ++        Q      E  ++   KR+  E  M  + E +IR   +  
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEEKI 493

Query: 509 RDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNK------ESQREKEKLEAELATAR 562
           R+  E++    +++ E+E    E+ R+   +++ + +      E  R+KEK+  +    R
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553

Query: 563 STNE----------DQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQAL-- 610
              E          DQ   I  +++ +   + K+ + EE++++++  + + E+M Q    
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613

Query: 611 ---VQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREK 667
               Q +  CE+ E+++ +   ++ R+ E +R Q+++   Q   + E       E+++E+
Sbjct: 614 KMGEQEEKMCEQEEKMQEQ-EEKMRRQEEKIREQEKKIREQEEKIREQE-----EMMQEQ 667

Query: 668 EERILALEADMTKWEQKYLEE 688
           EE++   E  M + E+K  E+
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQ 688



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 43/270 (15%), Positives = 127/270 (47%), Gaps = 8/270 (2%)

Query: 374 LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSR 433
           + +Q++ ++Q+       + ++Q++ Q+Q  + +    + +      +      +    +
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506

Query: 434 AQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAM 493
             +  +I  +E R  ++E+    EK+   +++  + +++ E  E + K   K    E+ M
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566

Query: 494 RNK------LEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKES 547
            ++       E ++ R  +  R+  E++    +++ E+E E +++  + + +   K  E 
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE-EMTQEQEEKMGEQEEKMCEQ 625

Query: 548 QREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEEL-KKKQVYVDKVEKM 606
           + + ++ E ++        +Q + I  +++ +   +  + + EE++ ++++   ++ EKM
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685

Query: 607 QQALVQLQAACEKREQLEHRLRTRLERELE 636
           Q+   +++   EK  + E RLR + E+  E
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 61/349 (17%), Positives = 161/349 (46%), Gaps = 32/349 (9%)

Query: 439 EILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSS---SKREALEKAMRN 495
           E L ++N  L+++L+    + + +Q    E++R  E  + L+      ++ + L K +++
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337

Query: 496 ---KLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKE 552
              KL+ ++     +NR L ++ E    +  EK  E  E  ++   ++  + ++ + ++E
Sbjct: 338 VSAKLQAQVEENELWNR-LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 396

Query: 553 KLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQ 612
           K+  +        E  RR    +++ +   + K+ + EE + +K+  + ++E+      +
Sbjct: 397 KMRRQEEMMWEKEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452

Query: 613 LQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERIL 672
           ++   EKR++ E ++R + +R+ +  ++ +++                 E +RE+EE+I 
Sbjct: 453 IREQEEKRQE-EEKIREQEKRQEQEAKMWRQE-----------------EKIREQEEKIR 494

Query: 673 ALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTAL---EARIQK 729
             E  M + E+K  E+  +R            +++  +            +   E +I+K
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554

Query: 730 EEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQ 778
           +EE++    ++  D E +I+    ++  ++  I+  +++ R++  K  +
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 53/294 (18%), Positives = 134/294 (45%), Gaps = 35/294 (11%)

Query: 376 QQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
           +++++ ++     H  ++ ++Q+ ++Q  E      + Q   A            + R +
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK-----------MWRQE 483

Query: 436 QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
           + +    ++ R   +++    EK+   +K+  E +R  +  E + +   K    E+  R 
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQ 541

Query: 496 K-----LEGEIR-----------RMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQ 539
           K      E +IR           +MHD    +RE+ E   +Q  EK  E  E  R+   +
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ-EEKIREQEEKIREQEEK 600

Query: 540 LFAKNKESQREKEKL---EAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELK-K 595
           +  + + +Q ++EK+   E ++       ++Q   +  +++ +   + K+ + EE+++ +
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660

Query: 596 KQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELE-SLRIQQRQGNCQ 648
           +++  ++ EKM +   ++    EK ++ E ++R + E+  E  +R++Q++   Q
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 99/456 (21%), Positives = 198/456 (43%), Gaps = 68/456 (14%)

Query: 377  QQQQQQQQHHHHHHHQQQQQ-QQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQ 435
            ++++++ QH      + QQ  Q+ ++Q  E  SA  + Q    + +       A + + +
Sbjct: 925  EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE-------AKLKKLE 977

Query: 436  QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAY---------------ENLV 480
            +   IL D+N  L +E +   +++A      TE +  S++                E L 
Sbjct: 978  EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037

Query: 481  KSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYE--------GSED 532
            +   +R+ LEK  R KLEG+   + D   +L+ ++     QLA+KE E          E 
Sbjct: 1038 REEKQRQELEKT-RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096

Query: 533  TRKTISQLFAKNKESQ--REKEKLEAELATARSTNEDQRRHI---------EIRDQALSN 581
             +K ++    +  ESQ    +E LE+E A +R+  E Q+R +         E+ D   S 
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERA-SRNKAEKQKRDLGEELEALKTELEDTLDST 1155

Query: 582  AQAKVV--KLEEELKKKQVYVDKVEKMQQALVQ------LQAACEKREQLEHRLRTRLER 633
            A  + +  K E+E+   +  +++  K  +A +Q       QA  E  EQLE   R +   
Sbjct: 1156 AAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 634  ELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRH 693
            E     ++  +G              L++   + E +   +EA + + + K+ E   +R 
Sbjct: 1216 EKAKQTLENERGEL------ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRT 1269

Query: 694  FALDAAATVAAQRD--TTVISHSPNTSYD-----TALEARIQKEEEEILMANKRCLDMEG 746
               D    +  + D  T ++S S + S       +ALE+++Q  +E +   N++ L +  
Sbjct: 1270 ELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST 1329

Query: 747  RIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCM 782
            ++K +     EK++  + L++    + +  +Q++ +
Sbjct: 1330 KLKQVED---EKNSFREQLEEEEEAKHNLEKQIATL 1362



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 66/317 (20%), Positives = 135/317 (42%), Gaps = 70/317 (22%)

Query: 435  QQMVEILSDENRNLRQELEGCYEKVARLQ--------KVETEIQRVSEAYENLVKS---- 482
            +Q VE +  +   L  EL+   +   RL+        + E ++Q   E  E   K     
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590

Query: 483  ----------SSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSE- 531
                        K+ ++  A R KLE +++ +        +  + A KQL + + +  + 
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650

Query: 532  -----DTRKTISQLFAKNKESQREKEKLEAEL--------ATARSTNEDQRRHIEIRDQA 578
                 DTR +  ++ A+ KE++++ + +EAE+        A  R+  + Q+   E+ D+ 
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710

Query: 579  LSNA-------------QAKVVKLEEELKKKQ----VYVDKVEKMQQALVQLQAAC---E 618
             +++             +A++ +LEEEL+++Q    +  D+++K    + Q+        
Sbjct: 1711 ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770

Query: 619  KREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADM 678
               Q     R +LER+ + L+++ ++   + T  S+Y A+            I ALEA +
Sbjct: 1771 SHAQKNENARQQLERQNKELKVKLQE--MEGTVKSKYKAS------------ITALEAKI 1816

Query: 679  TKWEQKYLEENVMRHFA 695
             + E++   E   R  A
Sbjct: 1817 AQLEEQLDNETKERQAA 1833



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 88/371 (23%), Positives = 163/371 (43%), Gaps = 78/371 (21%)

Query: 436  QMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRN 495
            Q +++  +E   +R EL    +KV +LQ    E+  V+     L +S SK   L K   +
Sbjct: 1255 QELQVKFNEGERVRTELA---DKVTKLQ---VELDNVTGL---LSQSDSKSSKLTKDF-S 1304

Query: 496  KLEGEIRRMHDFNRDLRERLETANKQ---LAEKEYEGSEDTRKTISQLFAKNKESQREKE 552
             LE +++       D +E L+  N+Q   L+ K  +  ++      QL    +E +  K 
Sbjct: 1305 ALESQLQ-------DTQELLQEENRQKLSLSTKLKQVEDEKNSFREQL----EEEEEAKH 1353

Query: 553  KLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQ 612
             LE ++AT  +   D ++ +E     L  A+    KL+++L          E + Q   +
Sbjct: 1354 NLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL----------EGLSQRHEE 1403

Query: 613  LQAACEKREQLEHRLRTRLERELESLRI---QQRQGNCQPTNVSEYNAAALMELLREKEE 669
              AA +K E    + +TRL++EL+ L +    QRQ  C             +E  ++K +
Sbjct: 1404 KVAAYDKLE----KTKTRLQQELDDLLVDLDHQRQSACN------------LEKKQKKFD 1447

Query: 670  RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQK 729
            ++LA E  ++    KY EE        D A   A +++T  +S +   + + A+E + + 
Sbjct: 1448 QLLAEEKTIS---AKYAEER-------DRAEAEAREKETKALSLA--RALEEAMEQKAEL 1495

Query: 730  E--------EEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSC 781
            E        E E LM++K   D  G  K++H     K A+ + +++   +     ++L  
Sbjct: 1496 ERLNKQFRTEMEDLMSSK---DDVG--KSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550

Query: 782  MRPAKSLMSIS 792
               AK  + ++
Sbjct: 1551 TEDAKLRLEVN 1561



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 56/214 (26%), Positives = 103/214 (48%), Gaps = 20/214 (9%)

Query: 433  RAQQMVEILSDENRNLRQE----LEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREA 488
            +AQQ  + L+DE  N   +    LE      AR+ ++E E++   +    L+    K+  
Sbjct: 1698 QAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE-EQGNTELINDRLKKAN 1756

Query: 489  LEKAMRNKLEGEIRRMH-DFNRDLRERLETANKQLAEK--EYEGSEDTRKTISQLFAKNK 545
            L+    N  +  + R H   N + R++LE  NK+L  K  E EG+  ++   S    + K
Sbjct: 1757 LQIDQINT-DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815

Query: 546  ESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEK 605
             +Q E E+L+ E    ++  +  RR     ++ L +    ++++++E +  + Y D+ +K
Sbjct: 1816 IAQLE-EQLDNETKERQAACKQVRR----TEKKLKDV---LLQVDDERRNAEQYKDQADK 1867

Query: 606  MQQALVQLQAACEKREQLEHRL---RTRLERELE 636
                L QL+   E+ E+   R    R +L+RELE
Sbjct: 1868 ASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 1901



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 95/478 (19%), Positives = 191/478 (39%), Gaps = 82/478 (17%)

Query: 374  LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSR 433
            L Q++ +Q+          + ++   ++Q  E   A    +   A+     AD    +  
Sbjct: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375

Query: 434  AQQMVEILSDENRNLRQELEGCY----EKVARLQKVETEIQRVSEAYENL-VKSSSKREA 488
            +   +E   +  R L+++LEG      EKVA   K+E    R+ +  ++L V    +R++
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435

Query: 489  ---LEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGS------EDTRKTISQ 539
               LEK  + K +  +      +    E  + A  +  EKE +        E+  +  ++
Sbjct: 1436 ACNLEKKQK-KFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE 1494

Query: 540  LFAKNKESQREKEKLEA----------ELATARSTNEDQRRHIEIRDQALS--------- 580
            L   NK+ + E E L +          EL  ++   E Q   ++ + + L          
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDA 1554

Query: 581  ------NAQAKVVKLEEEL--------KKKQVYVDKVEKMQQAL----VQLQAACEKREQ 622
                  N QA   + E +L        +KK+  V +V +M+  L     Q   A   R++
Sbjct: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614

Query: 623  LEHRLRTRLERELESL------------RIQQRQGNC-QPTNVSEYNAAALMELLREKEE 669
            LE  L+  LE  ++S             ++Q +  +C +  + +  +   ++   +E E+
Sbjct: 1615 LEMDLKD-LEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK 1673

Query: 670  RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTA------- 722
            ++ ++EA+M + +++          A + A   A Q    +     N+S   A       
Sbjct: 1674 KLKSMEAEMIQLQEELA--------AAERAKRQAQQERDELADEIANSSGKGALALEEKR 1725

Query: 723  -LEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQL 779
             LEARI + EEE+         +  R+K  + QI + +  + + +  ++K  +  +QL
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 73/334 (21%), Positives = 133/334 (39%), Gaps = 30/334 (8%)

Query: 456  YEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERL 515
            + KV  L +V  + + +    E LVK   K+ A E  +  ++E    ++      L+E+L
Sbjct: 831  FTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRL-TEMETLQSQLMAEKLQLQEQL 889

Query: 516  ETANKQLAEKEYEGSEDTRKT------ISQLFAKNKESQREKEKLEAELATARSTNEDQR 569
            +   +  AE E   +  T K          L A+ +E +   + L+AE    +   ++  
Sbjct: 890  QAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949

Query: 570  RHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQ-LEHRL- 627
              +E  + A    Q + V  E +LK       K+E+ Q  L        K ++ LE R+ 
Sbjct: 950  EQLEEEESARQKLQLEKVTTEAKLK-------KLEEEQIILEDQNCKLAKEKKLLEDRIA 1002

Query: 628  --RTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKY 685
               T L  E E  +   +  N     +++     L E LR +E++   LE    K E   
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITD-----LEERLRREEKQRQELEKTRRKLEGDS 1057

Query: 686  LEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDME 745
             + +       D  A + AQ     +  +       A  AR+++E  +  MA K+  ++E
Sbjct: 1058 TDLS-------DQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110

Query: 746  GRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQL 779
             +I  L   +  + A     +++ R    + E L
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEAL 1144



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 60/253 (23%), Positives = 106/253 (41%), Gaps = 39/253 (15%)

Query: 539  QLFAKNKE----SQREKEKL--EAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEE 592
            +LF K K     S++E+E +  E EL   R         +   +   S   A+ ++L+E+
Sbjct: 829  RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888

Query: 593  LKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNV 652
            L+ +     + E+++    +L A  ++ E++ H L  R+E E E  +  Q +      N+
Sbjct: 889  LQAETELCAEAEELR---ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945

Query: 653  SEYNAAALMELLREKEE--RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTV 710
             E     L E L E+E   + L LE   T+ + K LEE                     +
Sbjct: 946  QE-----LEEQLEEEESARQKLQLEKVTTEAKLKKLEEE-------------------QI 981

Query: 711  ISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSR 770
            I    N     A E ++   E+ I        + E + K+L     + +AMI  L++R R
Sbjct: 982  ILEDQNCKL--AKEKKLL--EDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037

Query: 771  KEPSKTEQLSCMR 783
            +E  + ++L   R
Sbjct: 1038 REEKQRQELEKTR 1050



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 46/206 (22%), Positives = 83/206 (40%), Gaps = 38/206 (18%)

Query: 605 KMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNC----------------- 647
           K+   ++  QA C  R  L  +   + +++L ++++ QR  NC                 
Sbjct: 778 KITDVIIGFQACC--RGYLARKAFAKRQQQLTAMKVLQR--NCAAYLKLRNWQWWRLFTK 833

Query: 648 -----QPTNVSEYNAAALMELLREKEERILALEADMTKWE---------QKYLEENVMRH 693
                Q +   E   A   EL++ +E++ LA E  +T+ E         +  L+E +   
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQ-LAAENRLTEMETLQSQLMAEKLQLQEQLQAE 892

Query: 694 FALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHA 753
             L A A     R T          +D  LEAR+++EEE           M+  I+ L  
Sbjct: 893 TELCAEAEELRARLTAKKQELEEICHD--LEARVEEEEERCQHLQAEKKKMQQNIQELEE 950

Query: 754 QIIEKDAMIKVLQQRSRKEPSKTEQL 779
           Q+ E+++  + LQ       +K ++L
Sbjct: 951 QLEEEESARQKLQLEKVTTEAKLKKL 976


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 64/208 (30%), Positives = 77/208 (37%), Gaps = 28/208 (13%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            P  P P  P  PL+ A     +       E    S           P P AAA  A    
Sbjct: 102  PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS---------CAPVPAAAAVAAGPEP 152

Query: 898  ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
            A A         A P A+AA A P     P P           P AA  +  +A++ ++ 
Sbjct: 153  APAGPAK----PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSH 208

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPA----------LVPVPAPAAAQASAPAQTQAPTSA 1007
              A  A A + V   PAA  P+P PA           V   AP A  A +P    AP +A
Sbjct: 209  HAA--APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAP-AA 265

Query: 1008 PAVAPTPAPTPTPAVAQAEVPASPATGP 1035
            PA AP P P P PA   A  P  PA  P
Sbjct: 266  PAAAP-PPPPPAPATL-ARPPGHPAGPP 291



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 66/182 (36%), Positives = 75/182 (41%), Gaps = 36/182 (19%)

Query: 872  SNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAA---AAPS 928
            +N  AA+ P+  P P A            A       A +P A  A AAPAAA     P+
Sbjct: 219  NNGPAALLPL--PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276

Query: 929  PATAA----------ATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978
            PAT A            A AV P AA Q   +A  A A A A    A  + Q  P A A 
Sbjct: 277  PATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA 336

Query: 979  VPAPAL-------VPVPAPAAAQ---ASAPAQTQA-----PT-----SAPAVAPTPAP-T 1017
             PAP +       V   AP AAQ   AS PA T A     PT      +PA  P PAP T
Sbjct: 337  APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396

Query: 1018 PT 1019
            PT
Sbjct: 397  PT 398



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 60/200 (30%), Positives = 78/200 (39%), Gaps = 32/200 (16%)

Query: 876  AAVAPISVPAPVAAAATAAAITATAATITT---------TMVAAAPVAVAAAAAPAAAAA 926
            AA +P + PAP A AA         AT+           T   A P   AA    +A AA
Sbjct: 253  AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312

Query: 927  PSPATAAATAAAVS----PAAAGQIP--------------AAASVASAAAVAPSAAAAAA 968
            P+PA AA   A VS    P AA   P              AA   A   A +  A+ AA+
Sbjct: 313  PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372

Query: 969  VQVAPAAPAPVPAPALVPVPAPAA----AQASAPAQTQAPTSAP-AVAPTPAPTPTPAVA 1023
            + + P     +P+PA VP PAP       + +A A TQ+ +  P A       T TP V 
Sbjct: 373  MVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVL 432

Query: 1024 QAEVPASPATGPGPHRLSIP 1043
               +P  P          +P
Sbjct: 433  APRLPQPPQNPTNIQNFQLP 452



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 67/210 (31%), Positives = 76/210 (36%), Gaps = 21/210 (10%)

Query: 841  PSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAP-ISVPAPVAAAATAAAITAT 899
            P P P   P        G     T        N   A AP +S+     AA       A 
Sbjct: 174  PGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA 233

Query: 900  AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAA--------A 951
              T+  T     P  V AAA PA AA   PA  A  A A +P      PA         A
Sbjct: 234  PGTVIQT-----PPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA 288

Query: 952  SVASAAAVAPSAAAAAAVQVAPAAPAPVPA---PALV---PVPAPAAAQASAPAQTQAPT 1005
               +AA   P  AAA     A AAPAP PA   PA V   P P  AAA  +   + ++P 
Sbjct: 289  GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348

Query: 1006 SAPAVAPTPAPTPTPAVAQAEVPASPATGP 1035
                 AP PA     A   A   AS   GP
Sbjct: 349  RVVQAAP-PAAQTLAASGPASTAASMVIGP 377



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 53/158 (33%), Positives = 59/158 (37%), Gaps = 14/158 (8%)

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P P   A   AA T   +        AA  AV+      AA  P P  AA      +P  
Sbjct: 184  PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPA----PALVPVPAPAAAQASAPA 999
             G   AAA  A AA   P+A A AA   AP  P P PA    P   P   P AA A  P 
Sbjct: 244  VG---AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300

Query: 1000 QTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGP 1037
                   +   AP PAP        A  PA  +  PGP
Sbjct: 301  AAAQNGGSAGAAPAPAPA-------AGGPAGVSGQPGP 331



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 48/154 (31%), Positives = 57/154 (37%), Gaps = 11/154 (7%)

Query: 886  PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAG 945
            P   AA A A+     + +    A A  A  A  AP AA  P PA  A       P   G
Sbjct: 48   PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGG-GPQRPG 106

Query: 946  QIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALV---PVPAPAAAQASAPAQTQ 1002
                   +  A    P+A      + +  + APVPA A V   P PAPA     A     
Sbjct: 107  PPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166

Query: 1003 APTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 1036
            A  + P   P P P P P       P  PA GPG
Sbjct: 167  AARAGPGPGPGPGPGPGPG------PGKPA-GPG 193



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 53/215 (24%), Positives = 76/215 (35%), Gaps = 35/215 (16%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITA 898
            + P+P P +        + G    +     G ++     V   + PA    AA+  A TA
Sbjct: 311  AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370

Query: 899  TAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAA 958
             +  I  TM  A P       +PAA   P+P T       +   AAG +  + S    A 
Sbjct: 371  ASMVIGPTMQGALP-------SPAAVPPPAPGTPTG----LPKGAAGAVTQSLSRTPTAT 419

Query: 959  VAPSAAAAAAVQVAPAAPAPVPAPA----------------------LVPVPAPAAAQAS 996
             +   A      +AP  P P   P                       ++P  A A  QA 
Sbjct: 420  TSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQ 479

Query: 997  APAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASP 1031
            A AQ Q  T AP  A TP   P   ++  + P +P
Sbjct: 480  AHAQPQT-TMAPRPA-TPTSAPPVQISTVQAPGTP 512



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 61/225 (27%), Positives = 71/225 (31%), Gaps = 54/225 (24%)

Query: 885  APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 944
            +P  AA    A  A  A         A  A      P     PSP      A    PAA 
Sbjct: 66   SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125

Query: 945  GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPA-------------PVPAPALVPVP--- 988
             + P   S  S A V  +AA AA  + APA PA             P P P   P P   
Sbjct: 126  LRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185

Query: 989  -----APAAAQ-------------ASAPAQTQAPTSAPAVAPTPAPT------------- 1017
                  P AAQ             A+APA +       A+ P P P              
Sbjct: 186  PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245

Query: 1018 ----PTPAVAQ---AEVPASPATGPGPHRLSIPSLTCNPDKTDGP 1055
                P PA      A  PA+PA  P P   +  +L   P    GP
Sbjct: 246  AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 55/179 (30%), Positives = 67/179 (37%), Gaps = 33/179 (18%)

Query: 903  ITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPS 962
            + + +V +    +AA+AA     AP      A AA     A G    + S A AA   P+
Sbjct: 21   VVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAG----ALGNHVVSGSPAGAAGAGPA 76

Query: 963  AAAAAAVQVAPAAPAPVPA--------------------PALVPVPAPAAAQASAPAQTQ 1002
            A A  A     AAP P PA                    P +   PAP AA+   P +  
Sbjct: 77   APAEGA---PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133

Query: 1003 APTSAPA-VAPTPAPTPTPAVAQAEVPASPA-----TGPGPHRLSIPSLTCNPDKTDGP 1055
            A + AP   A   A  P PA A    PA PA      GPGP     P     P K  GP
Sbjct: 134  AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP 192



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 51/159 (32%), Positives = 60/159 (37%), Gaps = 14/159 (8%)

Query: 889  AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAA--APSPATAAATAAAVSPAAAG- 945
            A  T     A A  +   +V+ +P A AA A PAA A  AP  A     A    P   G 
Sbjct: 44   APRTPEVRAAAAGALGNHVVSGSP-AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102

Query: 946  QIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAP-AAAQASAPAQTQAP 1004
            Q P   S       A  A  AA ++  P   A   AP  VP  A  AA    APA    P
Sbjct: 103  QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP--VPAAAAVAAGPEPAPAGPAKP 160

Query: 1005 TSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIP 1043
                A+A    P P P          P  GPGP + + P
Sbjct: 161  AGPAALAARAGPGPGPG-------PGPGPGPGPGKPAGP 192


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 57/227 (25%), Positives = 91/227 (40%), Gaps = 29/227 (12%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +P   STP+      T S+  S+ T     S  T+  +  S P      +T   +++ A+
Sbjct: 1065 TPADTSTPVT-----TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP 961
            T++TT     PV  +     +  A+ SP TA  T+   SP + G  P A+   S   V  
Sbjct: 1120 TLSTT-----PVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174

Query: 962  SAA---------AAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQ-------APT 1005
            S A         +   V  +  A +P P   +  +P     + S P  +        A +
Sbjct: 1175 SEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASS 1234

Query: 1006 SAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKT 1052
             A  ++ +P  T TP    AE  +SP T  G    S+P+ T +   T
Sbjct: 1235 EASTLSTSPVDTSTPVTTSAETSSSPTTAEG---TSLPTSTTSEGST 1278



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 63/260 (24%), Positives = 100/260 (38%), Gaps = 38/260 (14%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +PV  STP+ ++   T +R   T +E  +  N T +    + P      +T   +++ A+
Sbjct: 1713 TPVDNSTPVTTS---TEARSSPTTSEGTSMPNSTPSEG--TTPLTSIPVSTTPVLSSEAS 1767

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP 961
            T++ T     P+  +     +  A  SP TA  T+   S  + G  P  ++  S   VA 
Sbjct: 1768 TLSAT-----PIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVAN 1822

Query: 962  SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASA--------PAQTQAPTSAPAVA-- 1011
            S A+  +     +    V + A+   P PA   + A         A T  P S   VA  
Sbjct: 1823 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASS 1882

Query: 1012 ------PTPAPTPTPAVAQAEVPASPATGPG------------PHRLSIPSLTCNPDKTD 1053
                   TPA T TP    A+V +SP T  G            P   SIP  T     ++
Sbjct: 1883 ETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE 1942

Query: 1054 GPVFHSNTLERKTPIQILGQ 1073
                 +   + +TP+    Q
Sbjct: 1943 INTLSTTLADTRTPVTTYSQ 1962



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 63/271 (23%), Positives = 109/271 (40%), Gaps = 25/271 (9%)

Query: 791  ISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPL 850
            ++++ +G LS +   T +P+    +   S   + GI++     +E      S    +TP+
Sbjct: 2822 VASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPV 2881

Query: 851  LSAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPAPVAAAATAAAI-TATAA 901
             S+ + T S    D S      TE + +   A     PIS P+ V+   T+  + T   A
Sbjct: 2882 ASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVA 2941

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVS----------PAAAGQIPAAA 951
                + ++  PV        +A A+ SP TA  T+  +S            +   +P A+
Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS 3001

Query: 952  SVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL-VPVPAPAAAQ---ASAPAQTQ--APT 1005
            S AS  +  P+  +        A+ +P  A    +P+  P+       S P  T   A  
Sbjct: 3002 SEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIP 3061

Query: 1006 SAPAVAPTPAPTPTPAVAQAEVPASPATGPG 1036
             A  ++ TP  + +P V   EV +SP    G
Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEG 3092



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 50/220 (22%), Positives = 90/220 (40%), Gaps = 15/220 (6%)

Query: 842  SPVPPSTPLL----SAHSKTGSRDCSTQTERGTESNKTAAVAPIS---VPAPVAAAATAA 894
            SPV  STP+     ++ S T +   S  T   +E +      P+S   V +P A+     
Sbjct: 1242 SPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTT 1301

Query: 895  AITATAATITTTMVAAAPVAVAAAAAPAA--AAAPSPATAAATAAAVSPAAAGQIPAAAS 952
             +      +T+  V+++P      + P +  +   +P T+      +  ++A  I +   
Sbjct: 1302 PVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP 1361

Query: 953  VASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAP 1012
            V ++  V  S  A ++   +     P   P+    P  +   ++ P      + A  ++ 
Sbjct: 1362 VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPV---VSSEASTLSA 1418

Query: 1013 TPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKT 1052
            TP  T TP    AE  +SP T  G   +SIP+ T +  KT
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEG---ISIPTSTPSEGKT 1455



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 26/211 (12%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +PV  STP+      T +  CS+ T     S   +  +  + P      +T   +++ A+
Sbjct: 1360 TPVDNSTPV-----TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAS 1414

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP 961
            T++ T     PV  +     +A A  SP TA   +   S  + G+ P  +   S   VA 
Sbjct: 1415 TLSAT-----PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469

Query: 962  SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASA--------PAQTQAPTSAPAVA-- 1011
            S A+  +     +    V + A+   P PA   + A         A T  P S   VA  
Sbjct: 1470 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASS 1529

Query: 1012 ------PTPAPTPTPAVAQAEVPASPATGPG 1036
                   TPA T TP    ++  +SP T  G
Sbjct: 1530 EINSLSTTPAVTSTPVTTYSQASSSPTTADG 1560



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 79/379 (20%), Positives = 136/379 (35%), Gaps = 42/379 (11%)

Query: 712  SHSPNTSYDTALEARIQKEEEEIL--MANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRS 769
            S SP T+  T+++     E    L  M     L +     TL    ++    +    + S
Sbjct: 2023 SSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEAS 2082

Query: 770  RKEPSKTEQLSCMRPAK----------SLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKS 819
                ++   ++   P++          S   +++  +  LS +   + SP++       S
Sbjct: 2083 SSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS 2142

Query: 820  WKGSLGILLG-GDYRAEYVPSTPSPVPPSTPLLSAHS--KTGSRDCSTQTERGTESNKTA 876
               + G  +    Y     P T  PV  +    SA S   T   D ST     TE+  + 
Sbjct: 2143 PIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSP 2202

Query: 877  AVA-----PISVPAPVAAAATAAAI-TATAATITTTMVAAAPVAVAAAAAPAAAAAPSPA 930
              +     P S P+  +   T+  + T    T   + ++A PV  +     +  A  SP 
Sbjct: 2203 TTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPT 2262

Query: 931  TAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAV---------QVAPAAPAPVPA 981
            TA  T+   S  + G  P  +   S   VA S  +  +            +  A +P P 
Sbjct: 2263 TAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPT 2322

Query: 982  PALVPVPAPAAAQASAPAQTQAPTSAPAVA--------PTPAPTPTPAVAQAEVPASPAT 1033
                 +P   +++ + P  T+ P S   VA         TPA T TP    ++  +SP T
Sbjct: 2323 AEGTSMPTSTSSEGNTPL-TRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTT 2381

Query: 1034 GPGPHRLSIPSLTCNPDKT 1052
                   S+P+ T +   T
Sbjct: 2382 ADD---TSMPTSTYSEGST 2397



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 68/275 (24%), Positives = 112/275 (40%), Gaps = 22/275 (8%)

Query: 790  SISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPS--PVPPS 847
            ++    +G  S  +T  GS +      ++S   +  IL+     A    ST S  PV  S
Sbjct: 2662 TLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLT-NILVSTTLLANSEASTLSTTPVDTS 2720

Query: 848  TPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTM 907
            TP+    + +     S  T  GT S + +  +  S P      +T    ++ A+T++TT 
Sbjct: 2721 TPV----TTSAEASSSPTTAEGT-SMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTA 2775

Query: 908  V-AAAPVAVA--AAAAPAAAAAPS--PATAAATAAAVSPAAAGQIPAAASVASAAAVAPS 962
            V  + PV  +  A+++P  A   S   +T + T+  ++       P A+S A   +  P 
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPV 2835

Query: 963  AAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASA-----PAQTQ--APTSAPAVAPTPA 1015
              +        A+ +P  A  +V VP   A++ S      P  T   A + A  ++ TP 
Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIV-VPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPV 2894

Query: 1016 PTPTPAVAQAEVPASPATGPGPHR-LSIPSLTCNP 1049
             T  P     E  +SP T  G    +S PS    P
Sbjct: 2895 DTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTP 2929



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 58/236 (24%), Positives = 93/236 (39%), Gaps = 29/236 (12%)

Query: 834  AEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATA 893
            A +  ST S  P  T   S    T S+  S+ T     S  T+  +  S P      +T 
Sbjct: 2351 ASFETSTLSTTPADT---STPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTM 2407

Query: 894  AAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASV 953
              +++ A+T +TT     PV  +     +  A+ SP TA  T+   SP + G  P A+  
Sbjct: 2408 PVVSSEASTHSTT-----PVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462

Query: 954  ASAAAVAPSAAAAAA----------VQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
             S   V  S A   +               A+ +P  A  +V VP   A++ S    +  
Sbjct: 2463 VSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIV-VPISTASEGSTLLTSIP 2521

Query: 1004 PTSAPAVAP-------TPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKT 1052
             ++ P  +P       TP  + +P V   E+ +S  +  G    S+P+ T +   T
Sbjct: 2522 VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEG---TSMPTSTYSEGST 2574



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 58/240 (24%), Positives = 87/240 (36%), Gaps = 40/240 (16%)

Query: 848  TPLLS---AHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAI-------- 896
            TPL S   +H+   + + ST +    +SN     +     +P  A  T+ A         
Sbjct: 1808 TPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGST 1867

Query: 897  --------TATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP 948
                    T T A+  T  ++  P   +      A  + SP TA  ++   S    G+ P
Sbjct: 1868 ALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPP 1927

Query: 949  AAASVASAAAVAPSAAAAAAVQVAP----------AAPAPVPAPALVPVPAPAAAQASAP 998
              +   S   VA S     +  +A           A+ +P  A     +P PA ++ S P
Sbjct: 1928 LTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADG-TSMPTPAYSEGSTP 1986

Query: 999  AQTQAPTS--------APAVAPTPAPTPTPAVAQAEVPASPATGPGPH-RLSIPSLTCNP 1049
              T  P S        A  ++ TP  T TPA    E  +SP T  G   + S PS    P
Sbjct: 1987 L-TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTP 2045



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 47/221 (21%), Positives = 87/221 (39%), Gaps = 11/221 (4%)

Query: 844  VPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATI 903
            V  ST   S+ +  GS    +    G+    +  V+   V +P A+  +   + + +  I
Sbjct: 1604 VTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVI 1663

Query: 904  TTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAAS--VASAAAVAP 961
            T+T V+++P      + P +          +     +P A+  I   ++  V ++  V  
Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723

Query: 962  SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
            S  A ++   +     P   P+    P  +   ++ P  +   + A  ++ TP  T TP 
Sbjct: 1724 STEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLS---SEASTLSATPIDTSTPV 1780

Query: 1022 VAQAEVPASPATGPGPHRLSIPSLTCNPDK---TDGPVFHS 1059
                E  +SP T  G    SIP+ T +      T  PV H+
Sbjct: 1781 TTSTEATSSPTTAEG---TSIPTSTLSEGMTPLTSTPVSHT 1818



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 63/251 (25%), Positives = 102/251 (40%), Gaps = 34/251 (13%)

Query: 839  STP-SPVPPST-PLLSAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPA--- 885
            STP + VP ST P++S+ + T S    D ST     TE++ +   A     P S P+   
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455

Query: 886  -PVAA--AATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPA 942
             P+A+   +T   +++ A T++TT     PV  +     +  A+ SP TA      +S A
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTT-----PVDTSTPMTTSTEASSSPTTAEDIVVPISTA 2510

Query: 943  AAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQ 1002
            + G     +   S   VA   A+  +         PV + + V      ++ A++   T 
Sbjct: 2511 SEGSTLLTSIPVSTTPVASPEASTLST-------TPVDSNSPVVTSTEISSSATSAEGTS 2563

Query: 1003 APTSAPAVAPTP---APTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHS 1059
             PTS  +   TP    P  T  +A +E      T   P   SIP  T     +       
Sbjct: 2564 MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT---PVDTSIPVTTSTETSSSPTTAKD 2620

Query: 1060 NTLERKTPIQI 1070
             ++   TP ++
Sbjct: 2621 TSMPISTPSEV 2631



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 63/271 (23%), Positives = 108/271 (39%), Gaps = 44/271 (16%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSR---DCSTQTERGTESNKTAAVAPISVPAPVAAAATAA 894
            P T  PV   TP+ S+ + T S    D ST     T+++ +   A   +  P++ A+  +
Sbjct: 2811 PLTSMPVN-HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE-GIVVPISTASEGS 2868

Query: 895  AITATAATITTTMVAAA--------PVAVAAAAAPAAAAAPSPATAAATAAAVSPAA--- 943
             +  T+  ++TT VA++        PV  +     +   + SP TA  T+  +S  +   
Sbjct: 2869 TLL-TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS 2927

Query: 944  -------AGQIPAAASVASAAAVAP---------SAAAAAAVQVAPAAPAPVPAPALVPV 987
                      +P A S AS  +  P         SA A+++   A     P+  P     
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987

Query: 988  PAP---------AAAQASAPAQTQAPTSAPAVAPTPA-PTPTPAVAQAEVPASPATGPGP 1037
            P           A+++AS  ++T A TS P    T A  +PT A       ++P+ G  P
Sbjct: 2988 PLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTP 3047

Query: 1038 HRLSIPSLTCNPDKTDGPVFHSNTLERKTPI 1068
               SIP  T      +     +  ++  +P+
Sbjct: 3048 -LTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 67/303 (22%), Positives = 108/303 (35%), Gaps = 52/303 (17%)

Query: 787  SLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPP 846
            S+M + ++ +  LS +   T  P++       S   + G  +      E   STP     
Sbjct: 283  SVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTE--GSTPLT--- 337

Query: 847  STPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAAT---- 902
            STP  +    T      + T   T +  T +  P S+P    A +   +  +  +T    
Sbjct: 338  STPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTN 397

Query: 903  --ITTTMVAAA--------PVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAAS 952
              ++T +VA++        PV        A+ A+ SP TA  T+ A S  + G  P  + 
Sbjct: 398  MPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSM 457

Query: 953  VASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPA--- 1009
              S   VA S A+  +         PV +   V     A++          PTS P+   
Sbjct: 458  PVSTTPVASSEASNLST-------TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGS 510

Query: 1010 --------------------VAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNP 1049
                                ++ TP  T TP    +E  +S  T   P   SIP+ T + 
Sbjct: 511  TPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTT---PEGTSIPTSTPSE 567

Query: 1050 DKT 1052
              T
Sbjct: 568  GST 570



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 26/211 (12%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +PV  STP+      T S   S+ T     S  T+     S P      +T    ++ A+
Sbjct: 3481 TPVDTSTPVT-----TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAS 3535

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAV-- 959
            T++TT     PV        ++ A+ SPAT   T   +S  + G       + S+  V  
Sbjct: 3536 TLSTT-----PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTS 3590

Query: 960  -------APSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP------AQTQAPTS 1006
                    PS   +  V  +  + +    P ++ +P    ++ S P      + T    S
Sbjct: 3591 SEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTIS 3650

Query: 1007 APAVAPT-PAPTPTPAVAQAEVPASPATGPG 1036
                A T P  T TP +   +V +SP T  G
Sbjct: 3651 EAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 21/187 (11%)

Query: 844  VPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATI 903
            V  STPL ++   + S      T     +N   +    S+PA     A++ AIT     +
Sbjct: 182  VDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAIT----LL 237

Query: 904  TTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSA 963
            TT +  + PV +      +A A+ SP TA   + + S  + G  P      S   V  S 
Sbjct: 238  TTPVEISTPVTI------SAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSE 291

Query: 964  AAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVA 1023
            A+  +             PA   +P   + +AS+   T   TS P    T   TP  +  
Sbjct: 292  ASTLST-----------TPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTP 340

Query: 1024 QAEVPAS 1030
             + +P +
Sbjct: 341  ASTMPVA 347



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 63/302 (20%), Positives = 115/302 (38%), Gaps = 40/302 (13%)

Query: 791  ISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPL 850
            ++N+ +  LS +   T +P+        S   + G  +     ++      S +  + P+
Sbjct: 2704 LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763

Query: 851  LSAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPAPVAAAATAAAITAT--- 899
             S+ + T S    D S      TE++ +   A     P S P+  +   T+  +  T   
Sbjct: 2764 ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVA 2823

Query: 900  ---AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASA 956
               A T++TT     PV  +     +  A+ SP TA      +S A+ G     +   S 
Sbjct: 2824 SSEAGTLSTT-----PVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878

Query: 957  AAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAP 1016
              VA S A+  +             P    +P   + + S+   T   TS P   P+   
Sbjct: 2879 TPVASSEASTLST-----------TPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS 2927

Query: 1017 TPTPAVAQAEVP------ASPATGPGPHRLSIPS---LTCNPDKTDGPVFHSNTL-ERKT 1066
            TP  ++  + VP      ++ +T P   R  + +    + +P   +G     +T  ER+T
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987

Query: 1067 PI 1068
            P+
Sbjct: 2988 PL 2989



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 57/237 (24%), Positives = 88/237 (37%), Gaps = 25/237 (10%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAI-TATA 900
            +PV  +TPL ++   +     S  T  GT         P S P+  +   T+  + T T 
Sbjct: 3245 TPVDSNTPLTTSTEASS----SPPTAEGTS-------MPTSTPSEGSTPLTSMPVSTTTV 3293

Query: 901  ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA 960
            A+  T+ ++  P   +      + A+ SP  A  T+   S  + G  P      S   V 
Sbjct: 3294 ASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVV 3353

Query: 961  PSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTP---APT 1017
             S A+  +         PV     V     A+   +    T  PTS+P+   TP    P 
Sbjct: 3354 SSEASTLST-------TPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV 3406

Query: 1018 PTPAVAQAEVPASPATGPGPHRLSIPS--LTCNPDKTDGPVF-HSNTLERKTPIQIL 1071
             T  V  +EV     T    + L   S   + +P   +G     S T E  TP+ I+
Sbjct: 3407 STTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIM 3463



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 46/216 (21%), Positives = 83/216 (38%), Gaps = 20/216 (9%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +P   STP+      T S+  S+ T     S +T+  +  S P      +T   +++ A 
Sbjct: 1537 TPAVTSTPVT-----TYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEAN 1591

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSP----AAAGQIPAAASVASAA 957
            T++TT + +     A+  A ++  A   +   +T +  SP          P A+  AS  
Sbjct: 1592 TLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTL 1651

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAP-------AV 1010
            +  P  + +  +     + +P PA     +P     +   P  +    + P        +
Sbjct: 1652 STTPVDSNSPVITSTEVSSSPTPAEG-TSMPTSTYTEGRTPLTSITVRTTPVASSAISTL 1710

Query: 1011 APTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT 1046
            + TP    TP     E  +SP T  G    S+P+ T
Sbjct: 1711 STTPVDNSTPVTTSTEARSSPTTSEG---TSMPNST 1743



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 59/234 (25%), Positives = 88/234 (37%), Gaps = 36/234 (15%)

Query: 842  SPVPPSTPLLS---AHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITA 898
            +PV  STP+ +   AHS       S  T  GT S  T+  +  S P      +T   +++
Sbjct: 3128 TPVDTSTPVTTSTEAHS-------SPTTSEGT-SMPTSTPSEGSTPLTYMPVSTMLVVSS 3179

Query: 899  TAATITTTMV-AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
              +T++ T V  + PV  +  A        S  TA  T+   S  + G  P  +   S  
Sbjct: 3180 EDSTLSATPVDTSTPVTTSTEAT-------SSTTAEGTSIPTSTPSEGMTPLTSVPVSNT 3232

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQ--TQAPTSAPAVAPTP- 1014
             VA S A+  +           P  +  P+     A +S P    T  PTS P+   TP 
Sbjct: 3233 PVASSEASILST---------TPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPL 3283

Query: 1015 --APTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKT 1066
               P  T  VA +E      T   P   S P  T +   +  P+    ++   T
Sbjct: 3284 TSMPVSTTTVASSETSTLSTT---PADTSTPVTTYSQASSSPPIADGTSMPTST 3334



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 50/209 (23%), Positives = 79/209 (37%), Gaps = 29/209 (13%)

Query: 847  STPLLSAHSKT---GSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA--- 900
            STPL +    T    S + ST +    +S      A  +  +P  A  T+ A +  +   
Sbjct: 392  STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGS 451

Query: 901  ATITTTMVAAAPVAVAAAA-------------APAAAAAPSPATAAATAAAVSPAAAGQI 947
              +T+  V+  PVA + A+               +  A+ SP TA   +   S  + G  
Sbjct: 452  TPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511

Query: 948  PAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSA 1007
            P  +   S   VA S A+  +         PV     V   + A++ ++ P  T  PTS 
Sbjct: 512  PLTSMSVSTMPVASSEASTLST-------TPVDTSTPVTTSSEASSSSTTPEGTSIPTST 564

Query: 1008 PAVAPTP---APTPTPAVAQAEVPASPAT 1033
            P+   TP    P  T  V  +E   +  T
Sbjct: 565  PSEGSTPLTNMPVSTRLVVSSEASTTSTT 593



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 51/227 (22%), Positives = 84/227 (37%), Gaps = 41/227 (18%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +PV  ++P++     T +   S+ T     S  T+  +  S P      +T    ++ A+
Sbjct: 2538 TPVDSNSPVV-----TSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS 2592

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP 961
            T++TT     PV  +     +   + SP TA  T+  +S  +       + + S   VA 
Sbjct: 2593 TLSTT-----PVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVAS 2647

Query: 962  SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPA------------ 1009
            S A+  +         PV    LV      ++  +    +  PTS P             
Sbjct: 2648 SEASTLST-------TPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVS 2700

Query: 1010 -----------VAPTPAPTPTPAVAQAEVPASPATGPGPH-RLSIPS 1044
                       ++ TP  T TP    AE  +SP T  G   R+S PS
Sbjct: 2701 TTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPS 2747



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/256 (23%), Positives = 97/256 (37%), Gaps = 40/256 (15%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +PV  +TP+ ++   T     S+ T  GT S  T+     S P       T    ++ A+
Sbjct: 652  TPVDSNTPVTTSTEATS----SSTTAEGT-SMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP----------AAA 951
            T++TT     PV  +     +  A+ SP TA   +   S  + G  P            +
Sbjct: 707  TLSTT-----PVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTS 761

Query: 952  SVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL-VPVPAPAAAQASAPAQTQAPTS---- 1006
            S AS  +  P   +        A+ +P       +P+  P+     +P  T  P S    
Sbjct: 762  SEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPS---EGSPLLTSIPVSITPV 818

Query: 1007 ----APAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDK---TDGPVFHS 1059
                A  ++ TP  + +P     EV +SP    G    S+P+ T +  +   T  PV  S
Sbjct: 819  TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEG---TSMPTSTYSEGRTPLTSMPV--S 873

Query: 1060 NTLERKTPIQILGQEP 1075
             TL   + I  L   P
Sbjct: 874  TTLVATSAISTLSTTP 889



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 68/309 (22%), Positives = 107/309 (34%), Gaps = 40/309 (12%)

Query: 779  LSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLG-ILLGGDYRAEYV 837
            L+ M  +K+L++ S A        STL+ +P+        S + S       G       
Sbjct: 749  LTSMPVSKTLLTSSEA--------STLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIST 800

Query: 838  PSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            PS  SP+  S P+  + +   S + ST +    +SN     +     +P  A  T+   +
Sbjct: 801  PSEGSPLLTSIPV--SITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTS 858

Query: 898  A--------TAATITTTMVAAA--------PVAVAAAAAPAAAAAPSPATAAATAAAVSP 941
                     T+  ++TT+VA +        PV  +     +  A  SP T+  T+   S 
Sbjct: 859  TYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQT 1001
               G  P  +   S   V  S A   +         PV     V     A +  +    T
Sbjct: 919  PGEGSTPLTSMPDSTTPVVSSEARTLSA-------TPVDTSTPVTTSTEATSSPTTAEGT 971

Query: 1002 QAPTSAPAVAPTP---APTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFH 1058
              PTS P+   TP    P     VA +E      T   P   + P  T     +  P   
Sbjct: 972  SIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTT---PVDSNTPLTTSTEASSPPPTAE 1028

Query: 1059 SNTLERKTP 1067
              ++   TP
Sbjct: 1029 GTSMPTSTP 1037



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 54/222 (24%), Positives = 83/222 (37%), Gaps = 35/222 (15%)

Query: 847  STPLLS---AHSKTGSRDCSTQTERGTESNKTAAVAP-ISVPAPVAAAATAAAITA---- 898
            +TPL S   +H+   + + ST +    +SN     +   S P P A   +    T+    
Sbjct: 2278 TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGN 2337

Query: 899  ---TAATITTTMVAA--------APVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQ- 946
               T   ++TTMVA+         P   +      + A  SP TA  T+   S  + G  
Sbjct: 2338 TPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397

Query: 947  ---------IPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL-VPVPAPAAAQ-- 994
                     +P  +S AS  +  P   +        A+ +P  A    +P   P+     
Sbjct: 2398 PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 2457

Query: 995  -ASAPAQTQAPTSAPA--VAPTPAPTPTPAVAQAEVPASPAT 1033
             AS P  T    S+ A  ++ TP  T TP     E  +SP T
Sbjct: 2458 LASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTT 2499



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 60/318 (18%), Positives = 110/318 (34%), Gaps = 46/318 (14%)

Query: 800  SHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGS 859
            S  +TL+ +P+  + +   S + S      G       PS  SP+  S PL +  +   S
Sbjct: 2059 SEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST--TPVAS 2116

Query: 860  RDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITA--------TAATITTTMVAAA 911
             + ST +    +SN     +     +P+    T+   +         T+  ++TT+VA++
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASS 2176

Query: 912  --------PVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP-AAASVASAAAVAPS 962
                    PV  +     +  A  SP T+  T+   S  + G  P  +  V++   V   
Sbjct: 2177 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSE 2236

Query: 963  AAAAAAVQVAPAAPAPVPAPA-----------------------LVPVPAP----AAAQA 995
            A+  +A  V  + P      A                       L  +P      A ++ 
Sbjct: 2237 ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEV 2296

Query: 996  SAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGP 1055
            S  + T   ++ P    T A +P P      +P S ++        +P  T      +  
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETS 2356

Query: 1056 VFHSNTLERKTPIQILGQ 1073
               +   +  TP+    Q
Sbjct: 2357 TLSTTPADTSTPVTTYSQ 2374



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 48/213 (22%), Positives = 83/213 (38%), Gaps = 18/213 (8%)

Query: 842  SPVPPSTPLLSAH----SKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAIT 897
            +PV  STP+ ++     S T +   S  T   +E     A  P+S    V++     + T
Sbjct: 3363 TPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTT 3422

Query: 898  ---ATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVA 954
               +     T+T  +++P      + P      S  +  +T  ++ P +    P A+S A
Sbjct: 3423 PVDSNTLVTTSTEASSSPTIAEGTSLPT-----STTSEGSTPLSIMPLST--TPVASSEA 3475

Query: 955  SAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTP 1014
            S  +  P   +      +P   +P  A  +  +P   A + S P  T  P S   VA + 
Sbjct: 3476 STLSTTPVDTSTPVTTSSPTNSSPTTA-EVTSMPTSTAGEGSTPL-TNMPVSTTPVASSE 3533

Query: 1015 APT--PTPAVAQAEVPASPATGPGPHRLSIPSL 1045
            A T   TP  +   V +S      P  L + ++
Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTM 3566



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 59/247 (23%), Positives = 96/247 (38%), Gaps = 36/247 (14%)

Query: 839  STP-SPVPPSTPLL-SAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPAPVA 888
            +TP + +P ST L+ S+ + T S    D  TQ    TE++     A     P S P   +
Sbjct: 1159 TTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS 1218

Query: 889  AAATAAAITAT-AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQ- 946
               T+  +  T  A+   + ++ +PV  +     +A  + SP TA  T+   S  + G  
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST 1278

Query: 947  IPAAASVASAAAVAPSAAAAAAVQVAPAAP---------APVPAPALVPVPAPAAAQASA 997
            +  +  V++    +P A+      V    P         +P PA     +P    ++   
Sbjct: 1279 LLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEG-TSMPTSTYSEGRT 1337

Query: 998  PAQTQAPTSAPAVA--------PTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNP 1049
            P  T  P +   VA         TP    TP     E  +SP T  G    S+P+   NP
Sbjct: 1338 PL-TSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEG---TSMPN--SNP 1391

Query: 1050 DKTDGPV 1056
             +   P+
Sbjct: 1392 SEGTTPL 1398



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 48/195 (24%), Positives = 71/195 (36%), Gaps = 20/195 (10%)

Query: 857  TGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVA 916
            T S+  S+ T     S  T A +  S P      +T   +++ A+T++TT     PV  +
Sbjct: 1959 TYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTT-----PVDTS 2013

Query: 917  AAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPS-------AAAAAAV 969
              A  +   + SP TA  T+   S  +    P A    S   V  S           +  
Sbjct: 2014 TPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKT 2073

Query: 970  QVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVA--------PTPAPTPTPA 1021
            QV  +  A   A A       +A    +P  T  P S   VA         TP  + +P 
Sbjct: 2074 QVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPV 2133

Query: 1022 VAQAEVPASPATGPG 1036
            +   EV +SP    G
Sbjct: 2134 ITSTEVSSSPIPTEG 2148



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 52/230 (22%), Positives = 83/230 (36%), Gaps = 26/230 (11%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +P   STP+ ++   +     S  T  GT         PIS P+  +   T+  ++ T  
Sbjct: 3010 TPADTSTPVTTSTEASS----SPTTAEGTG-------IPISTPSEGSTPLTSIPVSTTPV 3058

Query: 902  TI-TTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA 960
             I   + ++  PV   +    +   + SP  A  T+  +S  + G  P      S   V 
Sbjct: 3059 AIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVT 3118

Query: 961  PSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTP---APT 1017
             SA       ++  +  PV     V     A +  +    T  PTS P+   TP    P 
Sbjct: 3119 SSA-------ISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPV 3171

Query: 1018 PTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTP 1067
             T  V  +E     AT   P   S P +T + + T        ++   TP
Sbjct: 3172 STMLVVSSEDSTLSAT---PVDTSTP-VTTSTEATSSTTAEGTSIPTSTP 3217



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 62/324 (19%), Positives = 116/324 (35%), Gaps = 38/324 (11%)

Query: 787  SLMSISNAGSGLLSHSSTLTGSPIME--EKRDDKSWKGSLGILLG----GDYRAEYVPST 840
            S M ++++ +  LS +   T +P+    E     +     GI +     G      +P +
Sbjct: 2995 STMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS 3054

Query: 841  PSPVP-PSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVA-PISVPAPVAAAATAAAITA 898
             +PV  P    LS      +    T TE  +        + PIS  +  +   T   ++ 
Sbjct: 3055 TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST 3114

Query: 899  TAATITT-TMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP--------- 948
            T  T +  + ++  PV  +     +  A  SP T+  T+   S  + G  P         
Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174

Query: 949  ----------AAASVASAAAVAPSAAAAAAVQV-APAAPAPVPAPALVPVPAP------- 990
                      +A  V ++  V  S  A ++      + P   P+  + P+ +        
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPV 3234

Query: 991  AAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPAS-PATGPGPHRLSIPSLTCNP 1049
            A+++AS  + T   ++ P    T A +  P      +P S P+ G  P   S+P  T   
Sbjct: 3235 ASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTP-LTSMPVSTTTV 3293

Query: 1050 DKTDGPVFHSNTLERKTPIQILGQ 1073
              ++     +   +  TP+    Q
Sbjct: 3294 ASSETSTLSTTPADTSTPVTTYSQ 3317



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 54/252 (21%), Positives = 89/252 (35%), Gaps = 53/252 (21%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSR---DCSTQTERGTESNKTAAVAPI-----------SV 883
            P T  PV  +TP+ S+ +   S    D  TQ    TE++ +   A +           S 
Sbjct: 453  PLTSMPVS-TTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511

Query: 884  PAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAA 943
            P    + +T    ++ A+T++TT     PV  +     ++ A+ S  T   T+   S  +
Sbjct: 512  PLTSMSVSTMPVASSEASTLSTT-----PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS 566

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
             G  P      S   V  S A+  +         P  +   V   + A++ ++    T  
Sbjct: 567  EGSTPLTNMPVSTRLVVSSEASTTST-------TPADSNTFVTTSSEASSSSTTAEGTSM 619

Query: 1004 PTS-----------------------APAVAPTPAPTPTPAVAQAEVPASPATGPGPHRL 1040
            PTS                       A  ++ TP  + TP     E  +S  T  G    
Sbjct: 620  PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG---T 676

Query: 1041 SIPSLTCNPDKT 1052
            S+P+ T     T
Sbjct: 677  SMPTSTYTEGST 688



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/254 (22%), Positives = 83/254 (32%), Gaps = 46/254 (18%)

Query: 833  RAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAAT 892
            R+    S  + +P STP   +   T   D +T          +A     S P   +  AT
Sbjct: 903  RSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEAT 962

Query: 893  AAAITATAATIT-------TTMVAAAPVAVAAAAAPAAA------------------AAP 927
            ++  TA   +I        TT + + PV+    A   A+                  A+ 
Sbjct: 963  SSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASS 1022

Query: 928  SPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPV 987
             P TA  T+   S  + G  P      S   VA S  +  +   A  +  PV   +    
Sbjct: 1023 PPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS-TPVTTYSQASS 1081

Query: 988  PAPAAAQASAPAQTQAPTSAP-----------------AVAPTPAPTPTPAVAQAEVPAS 1030
             +  A   S P  T +  S P                  ++ TP  T  P     E  +S
Sbjct: 1082 SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS 1141

Query: 1031 PATGPGPHRLSIPS 1044
            P T  G    SIP+
Sbjct: 1142 PTTAEG---TSIPT 1152



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/269 (20%), Positives = 96/269 (35%), Gaps = 39/269 (14%)

Query: 839  STPSPVPP--STPLLSAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPAPVA 888
            STP    P  +TP++S+ ++T S    D ST     TE+  +   A     P S P+   
Sbjct: 923  STPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982

Query: 889  AAATAAAITAT-AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQI 947
               T+  ++ T  A    + ++  PV        +  A+  P TA  T+   S  + G  
Sbjct: 983  TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST 1042

Query: 948  P----------AAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPA-------------- 983
            P           A+S  S  +  P+  +      + A+ +   A                
Sbjct: 1043 PLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTP 1102

Query: 984  LVPVPAPA----AAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHR 1039
            L  VP       +++AS  + T   TS P    T A +         +P SP +      
Sbjct: 1103 LTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 1162

Query: 1040 LSIPSLTCNPDKTDGPVFHSNTLERKTPI 1068
             S+P  T     ++     +  ++ KT +
Sbjct: 1163 ASMPVSTTLVVSSEANTLSTTPVDSKTQV 1191



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 49/247 (19%), Positives = 90/247 (36%), Gaps = 27/247 (10%)

Query: 831  DYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAA 890
            D    + PST +   P+ P+ +  S       S  TE  T          I +P+    +
Sbjct: 3901 DTSTTFTPSTDTASTPTIPVATTIS------VSVITEGSTPGTT------IFIPSTPVTS 3948

Query: 891  ATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAA 950
            +TA    AT   ++T ++ +  +       P+ +++ +  + + T    +PA     P  
Sbjct: 3949 STADVFPATTGAVSTPVITSTELNT-----PSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003

Query: 951  ASVASAAAVAP---SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPA----QTQA 1003
                S A   P   S     +     A   P  + ++   P   ++++S P+     T  
Sbjct: 4004 YVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIP 4063

Query: 1004 PTSAPAVAPTPAPTPTPAVA---QAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSN 1060
            PT  PA + TP  T   +     +A    +  T P     S P++T     T+  +  + 
Sbjct: 4064 PTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNP 4123

Query: 1061 TLERKTP 1067
            T     P
Sbjct: 4124 TSTPTVP 4130



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 58/304 (19%), Positives = 105/304 (34%), Gaps = 37/304 (12%)

Query: 787  SLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAE-YVPSTPSPVP 845
            S M ++++ +  LS +   T +P+        S     G  +     +E   P T  PV 
Sbjct: 519  STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578

Query: 846  PSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITT 905
                + S  S T +    + T   T S  +++       +   +  +    T T+ +++T
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638

Query: 906  TMVAAA--------PVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAA 957
            T+VA++        PV        +  A  S  TA  T+   S    G  P  +   +  
Sbjct: 639  TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT 698

Query: 958  AVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAP- 1016
             VA S A+  +                 PV        S  A +   T+  A  PT  P 
Sbjct: 699  LVASSEASTLST---------------TPVDTSTPVTTSTEASSSPTTADGASMPTSTPS 743

Query: 1017 ---TPTPAV---------AQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLER 1064
               TP  ++         ++A   ++       H  +    +C+P  T+G     +T   
Sbjct: 744  EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE 803

Query: 1065 KTPI 1068
             +P+
Sbjct: 804  GSPL 807



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 49/219 (22%), Positives = 81/219 (36%), Gaps = 29/219 (13%)

Query: 842  SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAA 901
            +P   STP+ +    + S   +  T     S  T+  +  S P    + +T   +++ A+
Sbjct: 3304 TPADTSTPVTTYSQASSSPPIADGT-----SMPTSTYSEGSTPLTNMSFSTTPVVSSEAS 3358

Query: 902  TITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP 961
            T++TT     PV  +     +  A+ SP TA  T+   S  + G  P A+   S   V  
Sbjct: 3359 TLSTT-----PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVS 3413

Query: 962  SAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPA 1021
            S       +V   +  PV +  LV               T+A +S      T  PT T +
Sbjct: 3414 S-------EVNTLSTTPVDSNTLVTT------------STEASSSPTIAEGTSLPTSTTS 3454

Query: 1022 VAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSN 1060
                 +   P +          +L+  P  T  PV  S+
Sbjct: 3455 EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS 3493



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 41/183 (22%), Positives = 69/183 (37%), Gaps = 11/183 (6%)

Query: 862  CSTQTERGT-ESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAA 920
            CST  E  + ES+ T+    +S         T +  T+ + + +TT+  ++    ++   
Sbjct: 85   CSTNPEMTSIESSVTSDTPGVS---STRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTT 141

Query: 921  PAAA----AAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAP 976
            P       + PS  + ++T A VS A      A  S+     ++     +     +P  P
Sbjct: 142  PEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTP 201

Query: 977  APVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVA--PTPAPTPTPAVAQAEVPASPATG 1034
                 P        +    S PA T    S+ A+    TP    TP    A+  +SP T 
Sbjct: 202  ESTTIPKSTNSEG-STPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA 260

Query: 1035 PGP 1037
             GP
Sbjct: 261  EGP 263



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 65/320 (20%), Positives = 115/320 (35%), Gaps = 47/320 (14%)

Query: 791  ISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTP-SPVPPST- 848
            ++++    LS +   T +P+        S   S G  +     +E   STP + +P ST 
Sbjct: 2173 VASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSE--GSTPFTSMPVSTM 2230

Query: 849  PLLSAHSKTGSR---DCSTQTERGTESNKTAAVAP-ISVPAPVAAAATAAAITATAATIT 904
            P++++ + T S    D ST     TE+  +   A   S+P    +  T      T+  ++
Sbjct: 2231 PVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPL---TSIPVS 2287

Query: 905  TTMVAAAPVAVAAAA--------APAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASA 956
             T+VA + V+  +            +  A+  P TA  T+   S ++ G  P      S 
Sbjct: 2288 HTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVST 2347

Query: 957  AAVA----------PSAAAAAAVQVAPAAPAPVPAP--------------ALVPVPAPA- 991
              VA          P+  +      + A  +P  A                L  VP    
Sbjct: 2348 TMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTM 2407

Query: 992  ---AAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCN 1048
               +++AS  + T   TS P    T A +         +P SP +       S+P  T  
Sbjct: 2408 PVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTP 2467

Query: 1049 PDKTDGPVFHSNTLERKTPI 1068
               ++     +  ++  TP+
Sbjct: 2468 VVSSEAGTLSTTPVDTSTPM 2487



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 44/205 (21%), Positives = 75/205 (36%), Gaps = 10/205 (4%)

Query: 838  PSTP--SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAA 895
            P+TP  + VP STP   + S T +   +                 +S P   +  A+++ 
Sbjct: 139  PTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSP 198

Query: 896  ITATAATIT-------TTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP 948
             T  + TI        +T + + P +    A+  A    +     +T   +S A A   P
Sbjct: 199  TTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS-AQASSSP 257

Query: 949  AAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAP 1008
              A   S +  APS  +    ++  +    V + A      PAA        T+A +S  
Sbjct: 258  TTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPT 317

Query: 1009 AVAPTPAPTPTPAVAQAEVPASPAT 1033
                T  PT T       + ++PA+
Sbjct: 318  TAEGTSIPTSTYTEGSTPLTSTPAS 342



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 44/190 (23%), Positives = 71/190 (37%), Gaps = 21/190 (11%)

Query: 838  PSTPSPVPPSTPLLSAHSKTGSR---DCSTQTERGTESNKTAAVA-----PISVPAPVAA 889
            P T  PV  +TP++S+ + T S    D ST      E+  +   A     P S P+    
Sbjct: 1397 PLTSIPVS-TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKT 1455

Query: 890  AATAAAITAT-AATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIP 948
               +  ++ T  A    + ++  PV   +    + A + SP  A  T+ A+S  + G   
Sbjct: 1456 PLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTA 1515

Query: 949  AAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAP 1008
              +   S   VA S   + +             PA+   P    +QAS+   T   TS  
Sbjct: 1516 LTSIPVSTTTVASSEINSLST-----------TPAVTSTPVTTYSQASSSPTTADGTSMQ 1564

Query: 1009 AVAPTPAPTP 1018
                +   TP
Sbjct: 1565 TSTYSEGSTP 1574



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 53/238 (22%), Positives = 92/238 (38%), Gaps = 33/238 (13%)

Query: 837  VPSTPSP-----VPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAV-APISVPAPVAAA 890
            V S+P+P     +  STP   + + T S   ST T   +E N  +   A  S P    + 
Sbjct: 1492 VSSSPTPAEGTSIAISTPSEGSTALT-SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQ 1550

Query: 891  ATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAA 950
            A+++  TA   ++ T+  +     + +          S A   +T    S          
Sbjct: 1551 ASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS---------- 1600

Query: 951  ASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAV 1010
             +  +A+  A S+  A    +  + P+   +P L  +P      AS  A T        +
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMTISTPSE-GSPLLTSIPVSTTPVASPEAST--------L 1651

Query: 1011 APTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPI 1068
            + TP  + +P +   EV +SP    G    S+P+ T     T+G    ++   R TP+
Sbjct: 1652 STTPVDSNSPVITSTEVSSSPTPAEG---TSMPTST----YTEGRTPLTSITVRTTPV 1702



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 56/263 (21%), Positives = 96/263 (36%), Gaps = 35/263 (13%)

Query: 800  SHSSTLTGSPIMEEKRDDKSWKGSL------GILLGGDYRAEYVPSTPSPVPPSTPLLSA 853
            S +STL+ +P+        S + SL      G  +     +E      S    +TP++S+
Sbjct: 3355 SEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSS 3414

Query: 854  HSKTGSR---DCSTQTERGTESNKTAAVAPI-----------SVPAPVAAAATAAAITAT 899
               T S    D +T     TE++ +  +A             S P  +   +T    ++ 
Sbjct: 3415 EVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE 3474

Query: 900  AATITTTMV-AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAA 958
            A+T++TT V  + PV        ++    SP TA  T+   S A  G  P      S   
Sbjct: 3475 ASTLSTTPVDTSTPVTT------SSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTP 3528

Query: 959  VAPSAAAAAAVQ--------VAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAV 1010
            VA S A+  +           + +  +  PA   V     +     + + T    S+  V
Sbjct: 3529 VASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYV 3588

Query: 1011 APTPAPTPTPAVAQAEVPASPAT 1033
              + A TP+        P + +T
Sbjct: 3589 TSSEASTPSTPSVDRSTPVTTST 3611



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 48/226 (21%), Positives = 80/226 (35%), Gaps = 37/226 (16%)

Query: 836  YVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAA-----VAPISVPAPVAAA 890
            YV S+ +  P STP         S D ST     T+SN T         P+S P+ V+  
Sbjct: 3587 YVTSSEASTP-STP---------SVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTP 3636

Query: 891  ATAAAITATAATI------------------TTTMVAAAPVAVAAAAAP--AAAAAPSPA 930
             T   ++ T+ TI                  T+T V+++PV       P    +   +P 
Sbjct: 3637 LTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPL 3696

Query: 931  TAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAP 990
            T    +     ++ G   +  SV ++  V  S  A ++     +    V  P  +     
Sbjct: 3697 TTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGT 3756

Query: 991  AAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 1036
                ++ P      +S P++      T       +E  +SP T  G
Sbjct: 3757 TILVSTTPVTRFPESSTPSI--PSVYTSMSMTTASEGSSSPTTLEG 3800



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 58/255 (22%), Positives = 93/255 (36%), Gaps = 46/255 (18%)

Query: 839  STPSPVPPSTPLLSAHSKTGSRDC---------STQTERGTESNK--TAAVAPISVPA-- 885
            STP P   STPLL++ +K GS            S  +ER T       +   P S P   
Sbjct: 3836 STP-PGDTSTPLLTS-TKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGAS 3893

Query: 886  -----PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAA-V 939
                 P+  + T    T TA+T T  +     V+V    +        P+T   ++ A V
Sbjct: 3894 IASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADV 3953

Query: 940  SPAAAGQIPAAASVASAAAVAPSAAAAAAVQ--------VAPAAPAPVPAPALVPVPAPA 991
             PA  G + +   + S     PS ++++             PA     P   +    AP+
Sbjct: 3954 FPATTGAV-STPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS 4012

Query: 992  AAQASA-----PAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPAS-----------PATGP 1035
              + ++      A T + TS P  + +    P    +++  P++           PA   
Sbjct: 4013 TPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSS 4072

Query: 1036 GPHRLSIPSLTCNPD 1050
             P   S  S T NP+
Sbjct: 4073 TPPTTSASSTTVNPE 4087



 Score = 30.8 bits (68), Expect = 7.2
 Identities = 42/223 (18%), Positives = 76/223 (34%), Gaps = 25/223 (11%)

Query: 851  LSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAA 910
            LS H +TGS   +  T  GT S           P    + +T   +T+  +++T+     
Sbjct: 55   LSQHVRTGS---AANTATGTTSTNVVE------PRMYLSCSTNPEMTSIESSVTSD---- 101

Query: 911  APVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQ 970
             P   +    P  +   S +T+ +T    S       P            PS  + ++  
Sbjct: 102  TPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISST- 160

Query: 971  VAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPAS 1030
            +A  + AP+P+            +A      +   S P    T A +         +P S
Sbjct: 161  MAFVSTAPLPS-----------FEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKS 209

Query: 1031 PATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQ 1073
              +       S+P+ T     ++     +  +E  TP+ I  Q
Sbjct: 210  TNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQ 252


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 61/250 (24%), Positives = 78/250 (31%), Gaps = 34/250 (13%)

Query: 837  VPSTPSPV----PPSTPLLSAHSKTGS-RDCSTQTERGTESNKTAAVAPISVPAPVAAAA 891
            V  TP+P     P +TP+ +  + T +     TQT   T    T  V P   P       
Sbjct: 1368 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT 1427

Query: 892  TAAAITATAATITTTMVAA-APVAVAAAAAPAAAAAPSPA-------TAAATAAAVSPA- 942
            T    T T  T T T     AP   A          P+P        T   T   V+P  
Sbjct: 1428 TTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1487

Query: 943  --AAGQIPAAASVASAAAVAPSAAAAAA--------VQVAPAAPAPVPAPALVPVPAPAA 992
                 Q P   ++ +   V P+                     P P P     P P P +
Sbjct: 1488 TPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIS 1547

Query: 993  AQASA-----PAQTQAPTSAP-----AVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042
               +      P  TQ PT+ P      V PTP PT T       +  +    P P   S 
Sbjct: 1548 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTST 1607

Query: 1043 PSLTCNPDKT 1052
             S T  P  T
Sbjct: 1608 KSTTVTPITT 1617



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 55/224 (24%), Positives = 73/224 (32%), Gaps = 32/224 (14%)

Query: 837  VPSTPSPV----PPSTPLLSAHSKTGS-RDCSTQTERGTESNKTAAVAPISVPAPVAAAA 891
            V  TP+P     P +TP+ +  + T +     TQT   T    T  V P   P       
Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404

Query: 892  TAAAITATAATIT---------TTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPA 942
            +    T T  T T         TT        V     P    AP+P TA  T + V+P 
Sbjct: 1405 STPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTP-TAITTTSTVTPT 1463

Query: 943  ---AAGQIPAAASVASAAAVAPSAAAAAAVQVAPAA--------PAPVPAPALVPVPAPA 991
                  Q P    + +   V P+          P A        P P P     P   P 
Sbjct: 1464 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPI 1523

Query: 992  AAQASA-----PAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPAS 1030
                +      P  TQ PT  P ++ T   TPTP     + P +
Sbjct: 1524 TTTTTVTPTPTPTGTQTPTPTP-ISTTTTVTPTPTPTGTQTPTT 1566



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 62/274 (22%), Positives = 87/274 (31%), Gaps = 37/274 (13%)

Query: 840  TPSPVPPSTPLLSAHSKTGSRDCS-TQTERGTESNKTAAVAPISVPAPVAAAATAAAITA 898
            TP+P P ST   +    T +   + T T  GT++  T  +   +   P          T 
Sbjct: 1323 TPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1382

Query: 899  TAATITTTMV-----------AAAPVAVAAAAAP------AAAAAPSPATAAATAAAVSP 941
            T  T TTT+             + P+       P            +P T   T      
Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1442

Query: 942  AAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAP-------APVPAPALVPVPAPAAAQ 994
                Q P   ++ + + V P+       Q     P        P P P     P P A  
Sbjct: 1443 PTGTQAPTPTAITTTSTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT 1501

Query: 995  AS-------APAQTQAPTSAP-AVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLT 1046
             +        P  TQ PTS P     T  PTPTP   Q   P   +T         P+ T
Sbjct: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGT 1561

Query: 1047 CNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMV 1080
              P  T  P+  + T+   TP     Q P   ++
Sbjct: 1562 QTPTTT--PITTTTTV-TPTPTPTGTQTPTTVLI 1592



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 56/236 (23%), Positives = 75/236 (31%), Gaps = 20/236 (8%)

Query: 837  VPSTPSPV----PPSTPLLSAHSKTGS-RDCSTQTERGTESNKTAAVAPISVPAPVAAAA 891
            V  TP+P     P STP+ +  + T +     TQT   T  + T  V P   P       
Sbjct: 1506 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPT 1565

Query: 892  TAAAITATAATITTTMVAA-APVAVAAAAAPAAAAAPSPA----------TAAATAAAVS 940
            T    T T  T T T      P  V           P+P           T   T  A  
Sbjct: 1566 TTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATP 1625

Query: 941  PAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALV---PVPAPAAAQASA 997
                 Q P    +++   V P+          P   +  P   L    P P  +  Q S 
Sbjct: 1626 TPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 1685

Query: 998  PAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLS-IPSLTCNPDKT 1052
               +    S   ++  P      + A    P +P T  G H LS  PS T +P  T
Sbjct: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 1741



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 50/218 (22%), Positives = 65/218 (29%), Gaps = 29/218 (13%)

Query: 863  STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATIT-----------TTMVAAA 911
            +T TE  T +  T        P P +  +T      T  T+T           TT     
Sbjct: 1305 TTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITT 1364

Query: 912  PVAVAAAAAPAAAAAP--SPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAV 969
               V     P     P  +P T   T          Q P +  + +   V P+       
Sbjct: 1365 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT-PTPTGT 1423

Query: 970  QVAPAAP-------APVPAPALVPVPAPAAAQASA-------PAQTQAPTSAP-AVAPTP 1014
            Q     P        P P P     P P A   ++       P  TQ PT+ P     T 
Sbjct: 1424 QTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTV 1483

Query: 1015 APTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKT 1052
             PTPTP   Q   P +  T         P+ T  P  T
Sbjct: 1484 TPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTST 1521



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 49/232 (21%), Positives = 82/232 (35%), Gaps = 27/232 (11%)

Query: 837  VPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAI 896
            V  TP+P    TP  +  + T +    T T  GT++  T  +   +   P     +  + 
Sbjct: 1552 VTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKST 1610

Query: 897  TATAATITTTMVAA-------APVAVAAAAAPAAAAAPSPATAAA------TAAAVSPAA 943
            T T  T TTT+ A         P  +  +        P+P T +       + A ++   
Sbjct: 1611 TVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELT 1670

Query: 944  AGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQA 1003
                P  +S    +    S    +   ++   PA +   +  P   P A   ++   T +
Sbjct: 1671 TSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA-IEMTSTAPPSTPTAPTTTSGGHTLS 1729

Query: 1004 PTSAPAVAPTPAPT----------PTPAVAQAEVPASPATGPGPHRLSIPSL 1045
            P  +   +P   PT          PTP+  Q    +  A  P P  LS PS+
Sbjct: 1730 PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS--AWTPTPTPLSTPSI 1779



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 39/174 (22%), Positives = 49/174 (28%), Gaps = 20/174 (11%)

Query: 899  TAATITTTMVAAAPVAVAAAAAPAA------AAAPSPATAAATAAAVSPAAAGQIPAAAS 952
            T  T TT      P+       P        +  P+P T   T          Q P    
Sbjct: 1302 TMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTP 1361

Query: 953  VASAAAVAPSAAAAAA--------VQVAPAAPAPVPAPALVPVPAPAAAQAS-----APA 999
            + +   V P+                     P P P     P   P     +      P 
Sbjct: 1362 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPT 1421

Query: 1000 QTQAPTSAP-AVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKT 1052
             TQ PT+ P     T  PTPTP   QA  P +  T         P+ T  P  T
Sbjct: 1422 GTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTT 1475



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 54/244 (22%), Positives = 93/244 (38%), Gaps = 49/244 (20%)

Query: 837  VPSTPSPVPPSTPLLSAHSKTGS-RDCSTQTERGTESNKTAAVAPI-----SVPAPVAAA 890
            V +TP+P    TP +   S T +     T T   T      + API     S P P ++ 
Sbjct: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680

Query: 891  ATAAAITATAATITTTMVAAAPVAV--AAAAAPAAAAAPSPATAAATAA---AVSPAAAG 945
               +  T++  T +TT+++  P A+   + A P+   AP+  +   T +   + + +  G
Sbjct: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740

Query: 946  QIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPV----PAPAAAQAS----- 996
                  +  S++A  PS             P P+  P+++      P P++         
Sbjct: 1741 TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLND 1800

Query: 997  ---APAQ-----TQAPT-----------------SAPAVAPTPAPTPTPAVAQAEVPASP 1031
               AP +     T   T                 S P+   TP+PTPTP+      P+ P
Sbjct: 1801 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPS---TPSPTPTPS-KSTPTPSKP 1856

Query: 1032 ATGP 1035
            ++ P
Sbjct: 1857 SSTP 1860


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.124    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,620,209
Number of Sequences: 37866
Number of extensions: 2877906
Number of successful extensions: 76742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1220
Number of HSP's successfully gapped in prelim test: 2371
Number of HSP's that attempted gapping in prelim test: 21779
Number of HSP's gapped (non-prelim): 25423
length of query: 1084
length of database: 18,247,518
effective HSP length: 113
effective length of query: 971
effective length of database: 13,968,660
effective search space: 13563568860
effective search space used: 13563568860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.