Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 15721939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15721939 metastatic lymph node 51 [Homo sapiens]
(703 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15721939 metastatic lymph node 51 [Homo sapiens] 1469 0.0
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 86 1e-16
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 82 1e-15
gi|146134388 YLP motif containing 1 [Homo sapiens] 80 8e-15
gi|160707881 formin 2 [Homo sapiens] 76 9e-14
gi|150170670 piccolo isoform 2 [Homo sapiens] 72 2e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 72 2e-12
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 72 2e-12
gi|150417989 cyclin K isoform 1 [Homo sapiens] 70 5e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 67 6e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 67 6e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 67 6e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 67 7e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 67 7e-11
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 66 1e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 2e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 3e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 64 4e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 5e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 64 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 6e-10
gi|18959210 WIRE protein [Homo sapiens] 63 8e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 1e-09
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 62 1e-09
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 62 2e-09
gi|33356148 formin-like 1 [Homo sapiens] 62 2e-09
gi|153792074 proline rich 12 [Homo sapiens] 62 2e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 60 5e-09
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 60 7e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 59 2e-08
>gi|15721939 metastatic lymph node 51 [Homo sapiens]
Length = 703
Score = 1469 bits (3803), Expect = 0.0
Identities = 703/703 (100%), Positives = 703/703 (100%)
Query: 1 MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALH 60
MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALH
Sbjct: 1 MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALH 60
Query: 61 LRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEAN 120
LRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEAN
Sbjct: 61 LRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEAN 120
Query: 121 DAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPA 180
DAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPA
Sbjct: 121 DAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPA 180
Query: 181 YIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALY 240
YIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALY
Sbjct: 181 YIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALY 240
Query: 241 GYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRN 300
GYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRN
Sbjct: 241 GYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRN 300
Query: 301 AAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVR 360
AAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVR
Sbjct: 301 AAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVR 360
Query: 361 DPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
DPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL
Sbjct: 361 DPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ
Sbjct: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
Query: 481 PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHI 540
PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHI
Sbjct: 481 PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHI 540
Query: 541 SIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLY 600
SIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLY
Sbjct: 541 SIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLY 600
Query: 601 PPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQV 660
PPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQV
Sbjct: 601 PPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQV 660
Query: 661 YGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS 703
YGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS
Sbjct: 661 YGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS 703
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 85.9 bits (211), Expect = 1e-16
Identities = 90/325 (27%), Positives = 105/325 (32%), Gaps = 81/325 (24%)
Query: 375 EKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPA 434
EK A PA P PPP P+ R L E +PPPP G +P
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPP--PLMNGLPPRP-----------PLPESLPPPPPGGLPL 261
Query: 435 PPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPN 494
PP+P T P P + PG P P
Sbjct: 262 PPMPPTGPAP------------------------------SGPPGPPQLPPPAP------ 285
Query: 495 HIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQ 554
G PP GV PPAP VH H P
Sbjct: 286 ----GVHPPAPVVHPPASGVH-----------------PPAPGVHPPAPGVHPPAPGVHP 324
Query: 555 GPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQ 614
H +P PP PG++ P PG+HP P PG++PPP + Q P
Sbjct: 325 PTSGVHPPAPGVHPPA-----PGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGV 379
Query: 615 QLLAPTYF-SAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQ 673
AP APGV +P APG P PP H P+ GV NP
Sbjct: 380 HPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVH--PSAPGVHPQPPGVHPSNPGVHP 437
Query: 674 VQPKPS---PPRRTPQPVTIKPPPP 695
P P PP + P I PPPP
Sbjct: 438 PTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/181 (30%), Positives = 76/181 (41%), Gaps = 24/181 (13%)
Query: 529 PVPE--PPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLH 586
P+PE PP PP + + P+ GP + P LPP PG++ P P +H
Sbjct: 246 PLPESLPPPPPGGLPL------PPMPPTGPAPSGPPGPPQLPPPA----PGVHPPAPVVH 295
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPP-- 644
P + P PG++PP + P P + + APGV +P APG PP
Sbjct: 296 PPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAP 355
Query: 645 ---PPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK-----PSPPRRTPQPVTIKPPPPE 696
PP P ++P A V+ +PA V P+ P P PQ + P PP
Sbjct: 356 GVHPPAPGVHPPPSA--GVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPG 413
Query: 697 V 697
V
Sbjct: 414 V 414
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/152 (32%), Positives = 60/152 (39%), Gaps = 25/152 (16%)
Query: 566 PLPPQGMLVQPGMNLPHPGL-------HPHQTPAPLPNPGLYP----PPVSMSPGQPP-P 613
P PP PG+ P P L P P P PG P PP +P PP P
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGP 277
Query: 614 QQLLAP---TYFSAPGVMNFGNPSYPYAPGALPP-----PPPPHLYPNTQAPSQVYGGVT 665
QL P + AP V + +P APG PP PP P ++P T GV
Sbjct: 278 PQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV- 336
Query: 666 YYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEV 697
+P V P P+P P P + PP P V
Sbjct: 337 --HPPAPGVHP-PAPGVHPPAP-GVHPPAPGV 364
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 82.4 bits (202), Expect = 1e-15
Identities = 157/691 (22%), Positives = 244/691 (35%), Gaps = 113/691 (16%)
Query: 38 GSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAED 97
G++GG G+G + + GA R + E+ + E ED + G+ +LS ++ D
Sbjct: 6 GASGGAGAGDDDFDQFDKPGAERSWRRRAAD----EDWDSELEDDLLGEDLLSGKKNQSD 61
Query: 98 SEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEP 157
EE ND + S E+ EE ++ + S E
Sbjct: 62 LSDEE----------------LNDDLLQSDNED--EENFSSQGVTISLNATSGMVTSFEL 103
Query: 158 VENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGR 217
+N + G + + ++++ + K E L Q EE + +G + +L +D+
Sbjct: 104 SDNTNDQSGEQESEYEQEQGEDELVYHKSDGSE--LYTQEYPEEGQYEGHEAELTEDQIE 161
Query: 218 W----EHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNW 273
+ E ++ DE E + + + + DIK + D
Sbjct: 162 YVEEPEEEQLYTDEVLDIEINEPLDEFTGGMETLELQKDIKEE-------SDEEEEDDEE 214
Query: 274 NGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYS------RSGGFKEGRAGFR 327
+G K+ R +G L T RN T +SA + R K+GR R
Sbjct: 215 SGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSR 274
Query: 328 PVEAGGQHGG----RSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEP 383
GG+ GG R + E + R R + P+ PV+
Sbjct: 275 ---RGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPT---QPPVV------------ 316
Query: 384 PAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPET--- 440
P A P PPP +PI + + V P PP+G+ PP ET
Sbjct: 317 PQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP-----HHPSPPQGM-HMPPQLETPRM 370
Query: 441 --TPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPS-FLQPRELRGMPNHIH 497
TP P T ++ G Q+ + P QP + P+ G P
Sbjct: 371 MMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPV---PSQPRPAVGPQRFPGPPEFPQ 427
Query: 498 MGAGPPPQ-FNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGP 556
GP P F++ + +Q Q + P P P + + +P +F
Sbjct: 428 HTPGPVPNSFSQPPRLPLQ--------DQWRAPPPPQDRDPFFLGVSG----EP-RFPSH 474
Query: 557 IYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPG----------LYPPPVSM 606
++ SP P PP L +N HP P Q+P P PG ++P +
Sbjct: 475 LFLEQRSPPPPPPPPTL----LNSSHPV--PTQSPLPFTQPGPAFNQQGQQPVFPRERPV 528
Query: 607 SPGQPPPQQLLAPTYFSAPGVMN---FGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGG 663
P PP + +FS PG F P P+ PG P P H PN Q P
Sbjct: 529 RPALQPPGPV-GILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLP 587
Query: 664 VTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
+ P QQ Q +P P + P +PPP
Sbjct: 588 PPH-QPQPQQPQQQPPPQHQPPHQPPHQPPP 617
Score = 43.9 bits (102), Expect = 5e-04
Identities = 74/295 (25%), Positives = 92/295 (31%), Gaps = 75/295 (25%)
Query: 390 AAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTG 449
A PPP DR S R + + + PPPP L + PVP +P P T+ G
Sbjct: 451 APPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPG 510
Query: 450 TWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRM 509
N QP F PRE + PP +
Sbjct: 511 ----------------------PAFNQQGQQPVF--PRE-----RPVRPALQPPGPVGIL 541
Query: 510 EEMGVQGGRAKRYSSQRQRPVPEPPAP--PVHISIMEGHYYDPLQFQGPIYTHGDSPAPL 567
+ + RQ +P P P P H QGP++ P P
Sbjct: 542 HFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQ---------PNLQGPLH----PPLPP 588
Query: 568 PPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGV 627
P Q QP P PHQ P P P PPP P Q PPQ
Sbjct: 589 PHQPQPQQPQQQPPPQHQPPHQPPHQ-PPPQHQPPP--QHPPQHPPQH------------ 633
Query: 628 MNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPR 682
+ + L PPPP L P +Q + P Q QP+ S R
Sbjct: 634 ------QHHHHHHHLSVPPPP-LMPMSQ---------PQFRPHVQTAQPQASSSR 672
Score = 35.0 bits (79), Expect = 0.24
Identities = 44/191 (23%), Positives = 62/191 (32%), Gaps = 31/191 (16%)
Query: 364 PEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEE 423
P+ P P + + +PP P PPP P + + +
Sbjct: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHL--------S 643
Query: 424 VPPPPEGLIPAPPVPE--TTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAE---QNWSP 478
VPPPP + P T P + + P GL + N+++ Q P
Sbjct: 644 VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCP---QRQGLRHNTTSQNVSKRPMQQMQP 700
Query: 479 GQPSFLQPRELRGMPNHI------HMGAGPPPQFNRM-----EEMGVQGGRAKRYSSQRQ 527
P REL P+H+ A P Q + V G R SSQ +
Sbjct: 701 TAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSR----SSQGK 756
Query: 528 RPVPEPPAPPV 538
V PA PV
Sbjct: 757 TEVKVKPASPV 767
Score = 29.6 bits (65), Expect = 10.0
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 8/67 (11%)
Query: 636 PYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPP-- 693
P P A PPPPPP P Q ++ Q PSPP+ P ++ P
Sbjct: 314 PVVPQAPPPPPPP---PQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRM 370
Query: 694 ---PPEV 697
PP V
Sbjct: 371 MMTPPPV 377
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 79.7 bits (195), Expect = 8e-15
Identities = 90/306 (29%), Positives = 114/306 (37%), Gaps = 73/306 (23%)
Query: 425 PPPPEGLIPAPP---VPETTPTPPTKTGTWEAPVDSS--TSGLEQDVAQLNIAEQNWSPG 479
PPPP +P PP +PE +P P + T A SS S EQ +AQL +Q
Sbjct: 15 PPPP---VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
Query: 480 QPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVH 539
LQP L P PPP + GG Y + P P PP P
Sbjct: 72 MQCVLQPHHLPPPPL-------PPPPV-------MPGGG---YGDWQPPPPPMPPPPGPA 114
Query: 540 ISIMEGHYYDPLQFQGPIYTHGDSPAPL-------PPQGMLVQPGMNLPHPGLHPHQT-- 590
+S + Y ++ D P L PP+ V PG +P P Q+
Sbjct: 115 LSYQKQQQYKHQM----LHHQRDGPPGLVPMELESPPESPPVPPGSYMP-----PSQSYM 165
Query: 591 PAPLPNPGLYPP--------PVSMSPGQPPPQQ-LLAPT---YFSAPGVMNFGNPSYPYA 638
P P P P YPP P SP Q PP Q LAPT S+ ++ + S Y
Sbjct: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYL 225
Query: 639 PGA---------------LPPPPPPHLYPNTQAPSQ---VYGGVTYYNPAQQQVQPKPSP 680
P + L PPPP P + Q + G + QQQ P+P P
Sbjct: 226 PSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDP 285
Query: 681 PRRTPQ 686
TPQ
Sbjct: 286 STMTPQ 291
Score = 52.4 bits (124), Expect = 1e-06
Identities = 87/383 (22%), Positives = 127/383 (33%), Gaps = 71/383 (18%)
Query: 341 ETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIE 400
E VK E++ + TS SP ++ P L P +E PP P + P D ++
Sbjct: 328 EPVKEEVT-----VPATSQVPESPSSEEPPLPPPNEEVPPPLPPEE-PQSEDPEEDARLK 381
Query: 401 KKSYSRA---RRTRTKVGDAVK-------LAEEVPPPPEGLIPAPPVPETTPTPPTKTGT 450
+ + A + + +VG + +++ + +I PP +T
Sbjct: 382 QLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMS-------- 433
Query: 451 WEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRME 510
VD E Q Q W RE + +H P ++++
Sbjct: 434 ----VDMQLRHYEMQQQQFQHLYQEWE---------REFQLWEEQLHSY----PHKDQLQ 476
Query: 511 EMGVQG----GRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAP 566
E Q G K S Q V M+ Y + P + P P
Sbjct: 477 EYEKQWKTWQGHMKATQSYLQEKVNS-------FQNMKNQYMGNMSMPPPFVPYSQMPPP 529
Query: 567 LPPQGMLVQPGMNLPHPGLHPHQTPAPLPN--PGLYPPPVSMSPGQPPPQQLLAPTYFSA 624
LP +P P L P P +P P PPP P PP P
Sbjct: 530 LP----------TMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMP 579
Query: 625 PGVMNFGNPSY---PYAPGALPPP--PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPS 679
P + + G P P A PPP PPP L ++ AP V + P P
Sbjct: 580 PSLSSAGPPPVLPPPSLSSAGPPPVLPPPSL--SSTAPPPVMPLPPLSSATPPPGIPPPG 637
Query: 680 PPRRTPQPVTIKPPPPEVVSRGS 702
P+ P +T P PP S+ S
Sbjct: 638 VPQGIPPQLTAAPVPPASSSQSS 660
Score = 50.8 bits (120), Expect = 4e-06
Identities = 40/124 (32%), Positives = 49/124 (39%), Gaps = 19/124 (15%)
Query: 597 PGLYPPPVSMSPGQP---PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALP---PPPPPHL 650
PG+YPPP S P P PP ++ P+ A + P P P P PPPPP +
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562
Query: 651 YPNTQAPSQ------VYGGVTYYNPAQ-------QQVQPKPSPPRRTPQPVTIKPPPPEV 697
P T A Q + G+ N Q + PS P P PV PPP
Sbjct: 1563 KPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP 1622
Query: 698 VSRG 701
V G
Sbjct: 1623 VPMG 1626
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/202 (26%), Positives = 68/202 (33%), Gaps = 53/202 (26%)
Query: 524 SQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPH- 582
S P P PP PPV + P GP Y+ +PA G + +L
Sbjct: 11 SSHYPPPPVPPPPPVAL---------PEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
Query: 583 ---PGLHPHQT-----PAPLPNPGLYPPPVSMSPG----QPPPQQLLAPTYFSAPGVMNF 630
+H Q P LP P L PPPV G QPPP + P P +
Sbjct: 62 QQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPP---GPALSYQ 118
Query: 631 GNPSYPYA---------PGALP-----PPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQP 676
Y + PG +P PP P + P + Y P Q P
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGS------------YMPPSQSYMP 166
Query: 677 KPSPPRRTPQPVTIKP--PPPE 696
P PP P + +P PP +
Sbjct: 167 PPQPPPSYYPPTSSQPYLPPAQ 188
Score = 37.7 bits (86), Expect = 0.037
Identities = 64/322 (19%), Positives = 108/322 (33%), Gaps = 75/322 (23%)
Query: 362 PSPEADAPVLGSPEKEEAASE--------PPAAAP-DAAPPPPDRPIEKKSYSRARRTRT 412
P P P L ++++ + PP P + PP P+ SY ++
Sbjct: 106 PMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYM 165
Query: 413 KVGDAVKLAEEVPPPPEGLIPA--------PPVPETTPTPPTKTGTWEAPVDSSTSGLEQ 464
P PP P P P + +PP+++ P SS+S Q
Sbjct: 166 PP----------PQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQ 215
Query: 465 DV---AQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKR 521
+Q + SP +PS + P + PP +++ ++ G AK
Sbjct: 216 SYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPP---PSAPPGNKTTVQQEPLESG-AKN 271
Query: 522 YSSQRQRPVPEPPAPPVHISIMEGHYYDP----LQFQGPIYTHGDSPAPLPPQGMLVQPG 577
S+++Q+ PEP + + ++Y LQ + ++ G P+ +
Sbjct: 272 KSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK------- 324
Query: 578 MNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPY 637
+ P P PA P P S P PPP +
Sbjct: 325 -DTPEPVKEEVTVPATSQVP---ESPSSEEPPLPPPNE---------------------- 358
Query: 638 APGALPPPPPPHLYPNTQAPSQ 659
+PPP PP P ++ P +
Sbjct: 359 ---EVPPPLPPE-EPQSEDPEE 376
Score = 36.6 bits (83), Expect = 0.082
Identities = 82/356 (23%), Positives = 104/356 (29%), Gaps = 97/356 (27%)
Query: 359 VRDPSPEADAPVLGSPEKEEAASEPPAAAP---DAAPPPPDRPIEKKSYSRARRTRTKVG 415
V PS P G P +A PP P +A PPP P
Sbjct: 564 VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP----------------- 606
Query: 416 DAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQN 475
L+ PPP ++P PP+ TP P
Sbjct: 607 -PPSLSSTAPPP---VMPLPPLSSATPPPGIP---------------------------- 634
Query: 476 WSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPA 535
PG P +G+P + PP SS + VPE P
Sbjct: 635 -PPGVP--------QGIPPQLTAAPVPPA------------------SSSQSSQVPEKPR 667
Query: 536 P---PVHISIMEG---HYYDPLQFQGPIYTHGDSPAPLPPQGM---LVQPGMNLPHPGLH 586
P P +S Y+ PLQ GP +S APL + L
Sbjct: 668 PALLPTPVSFGSAPPTTYHPPLQSAGP-SEQVNSKAPLSKSALPYSSFSSDQGLGESSAA 726
Query: 587 PHQ-----TPAPLPNPGLYP-PPVSMSPGQPPPQQLLAPTYFSAPGVMNFG-NPSYPYAP 639
P Q P+ + GL P PP S P + P F G G P P
Sbjct: 727 PSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFE 786
Query: 640 GALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQ-QVQPKPSPPRRTPQPVTIKPPP 694
G P P P + ++ G+ PA Q + P S R P P P
Sbjct: 787 GNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKP 842
Score = 36.2 bits (82), Expect = 0.11
Identities = 54/232 (23%), Positives = 68/232 (29%), Gaps = 62/232 (26%)
Query: 426 PPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQ 485
PPP +P P +P + P P P G+ V ++ PG P L
Sbjct: 527 PPPLPTMPPPVLPPSLPPPVMPPA---LPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLS 583
Query: 486 PRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEG 545
AGPPP P P PP +S
Sbjct: 584 -------------SAGPPPVLP---------------PPSLSSAGPPPVLPPPSLSSTAP 615
Query: 546 HYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPL----------- 594
PL P + P +PP G+ G+ P T AP+
Sbjct: 616 PPVMPL----PPLSSATPPPGIPPPGV---------PQGIPPQLTAAPVPPASSSQSSQV 662
Query: 595 ---PNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALP 643
P P L P PVS G PP P + P N P + ALP
Sbjct: 663 PEKPRPALLPTPVSF--GSAPPTTYHPPLQSAGPSEQ--VNSKAPLSKSALP 710
Score = 34.7 bits (78), Expect = 0.31
Identities = 42/162 (25%), Positives = 58/162 (35%), Gaps = 31/162 (19%)
Query: 478 PGQPSFLQPRELRGMPNHIHMGAGPPP-QFNRMEEMGVQGGRAKRYSSQRQR-------- 528
P L P+E R G PPP + MG G R S+ R
Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542
Query: 529 --PVPEPPAPPV----------HISIMEGHYYDPLQFQGPIYTHGDSP--APLPPQGMLV 574
P+P PP PP S +E +D F G T+ + + + +
Sbjct: 1543 PVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAI 1602
Query: 575 QPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSP-GQPPPQQ 615
LP P +H + +P PG P P+ M P +PPP Q
Sbjct: 1603 PSAPVLPPPPVH-----SSIPPPG--PVPMGMPPMSKPPPVQ 1637
Score = 33.9 bits (76), Expect = 0.53
Identities = 24/102 (23%), Positives = 40/102 (39%), Gaps = 4/102 (3%)
Query: 518 RAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
R ++ Q+ + P H+ E + G +Y S P PP G +P
Sbjct: 1467 REQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPG-MYPPPGSYRPPPPMG---KPP 1522
Query: 578 MNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAP 619
++ P P ++ P+ P + PP P PPP ++ P
Sbjct: 1523 GSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKP 1564
Score = 33.1 bits (74), Expect = 0.90
Identities = 31/99 (31%), Positives = 36/99 (36%), Gaps = 28/99 (28%)
Query: 612 PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPP---PPHLYPNTQAPSQVYGGVTYYN 668
PPQ+ S PG+ YP PPPP PP AP
Sbjct: 1490 PPQESRLQNTSSRPGM-------YPPPGSYRPPPPMGKPPGSIVRPSAP----------- 1531
Query: 669 PAQQQVQ----PKPSPPRRTPQPVTIKPPPPEVVSRGSS 703
PA+ V P P PP P P PPPP V+ +S
Sbjct: 1532 PARSSVPVTRPPVPIPPPPPPPP---LPPPPPVIKPQTS 1567
Score = 31.2 bits (69), Expect = 3.4
Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 16/93 (17%)
Query: 377 EEAASEPPAAAPDAAPPP----PDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLI 432
+E+ + ++ P PPP P P+ K S R + +V + PP +
Sbjct: 1492 QESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR----PPVPIP 1547
Query: 433 PAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQD 465
P PP P P PP + TS +EQ+
Sbjct: 1548 PPPPPPPLPPPPPV--------IKPQTSAVEQE 1572
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 76.3 bits (186), Expect = 9e-14
Identities = 100/397 (25%), Positives = 135/397 (34%), Gaps = 43/397 (10%)
Query: 331 AGGQHGGRSGETVKHEISYRSRRLEQTSVR----------DPSPEADAPVLGSPEKEEAA 380
A G G +G T ++ + RLE+ VR SP + VL P +
Sbjct: 705 ASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLP 764
Query: 381 SEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEV--PPPPEGLIPAPPVP 438
PP P A P + + S + R + D+ + + + PPPP L+ +
Sbjct: 765 GRPPCP-PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQG 823
Query: 439 ETTPTPPTKTGT-WEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIH 497
+ PP T ++ + S S ++ + P P MP +
Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI--------PSPPPLPCTESSSSMPG-LG 874
Query: 498 MGAGPPPQFNRMEEMGVQGGRAKR---YSSQRQRPVPEPPAPPVHISI---MEGHYYDPL 551
M PPP M + + P P PP P I + G PL
Sbjct: 875 MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL 934
Query: 552 QFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQP 611
P P P P G + P LP G+ P PLP G+ PPP G P
Sbjct: 935 ----PPLPGAGIPPPPPLPGAAIPPPPPLPGAGI---PLPPPLPGAGIPPPPPLPGAGIP 987
Query: 612 PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYG-GVTYYNPA 670
PP L P + G P P PGA PPPPP P + G G+ P
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 671 QQQVQPKPSP------PRRTPQPVTIKPPPPEVVSRG 701
P P P P P P PPPP + G
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Score = 70.9 bits (172), Expect = 4e-12
Identities = 97/354 (27%), Positives = 113/354 (31%), Gaps = 99/354 (27%)
Query: 354 LEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA-PPPPDRPIEKKSYSRARRTRT 412
L + P P A + P A PP P A PPPP P
Sbjct: 970 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-------------- 1015
Query: 413 KVGDAVKLAEEVPPPPE----GLIPAPPVPET--TPTPPTKTGTWEAPVDSSTSGLEQDV 466
+PPPP G+ P PP+P P PP P +G+
Sbjct: 1016 --------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---- 1063
Query: 467 AQLNIAEQNWSPGQPSFLQPRELRGMPNHIHM-GAGPPPQFNRMEEMGVQGGRAKRYSSQ 525
P P P G+P + GAG PP + G+
Sbjct: 1064 -----------PPPP----PLPGAGIPPPPPLPGAGIPPP-PPLPGAGIP---------- 1097
Query: 526 RQRPVPEPPAPPVHISIMEGHYYDPLQFQG----PIYTHGDSPAPLPPQGMLVQPGMNLP 581
P PP P V I PL G P P P P G + P LP
Sbjct: 1098 -----PPPPLPGVGIPPPP-----PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147
Query: 582 HPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGA 641
G+ P P PLP G+ PPP G PPP L P + G P P PGA
Sbjct: 1148 RVGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA 1204
Query: 642 LPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
PPPPP P P P P+PP P P T PPPP
Sbjct: 1205 GIPPPPP--LPGMGIP------------------PAPAPP--LPPPGTGIPPPP 1236
Score = 69.7 bits (169), Expect = 9e-12
Identities = 94/353 (26%), Positives = 108/353 (30%), Gaps = 100/353 (28%)
Query: 354 LEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA-PPPPDRPIEKKSYSRARRTRT 412
L + P P A +L P A PP P AA PPPP P
Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-------------- 960
Query: 413 KVGDAVKLAEEVPPPPEGLIPAPPVPET-TPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI 471
G + L P P G+ P PP+P P PP G P
Sbjct: 961 --GAGIPLPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----------------- 999
Query: 472 AEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVP 531
P L G G PPP P+P
Sbjct: 1000 --------------PPPLPGA------GIPPPP------------------------PLP 1015
Query: 532 E---PPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPH 588
PP PP + G P P P P P G + P LP G+ P
Sbjct: 1016 GAGIPPPPP-----LPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP- 1065
Query: 589 QTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPP 648
P PLP G+ PPP G PPP L P + G P P PGA PPPPP
Sbjct: 1066 --PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1123
Query: 649 HLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRG 701
P + G P +V P P P P PPPP + G
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP----PLPGAGIPPPPPLPGAG 1172
Score = 55.1 bits (131), Expect = 2e-07
Identities = 85/333 (25%), Positives = 100/333 (30%), Gaps = 84/333 (25%)
Query: 354 LEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA-PPPPDRPIEKKSYSRARRTRT 412
L + P P A + P A PP P A PPPP P
Sbjct: 1014 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-------------- 1059
Query: 413 KVGDAVKLAEEVPPPPE----GLIPAPPVPET-TPTPPTKTGTWEAPVDSSTSGLEQDVA 467
+PPPP G+ P PP+P P PP G P +
Sbjct: 1060 --------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--------PPPLP 1103
Query: 468 QLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQ 527
+ I PG P L G G PPP + G+
Sbjct: 1104 GVGIPPPPPLPGA-GIPPPPPLPGA------GIPPPPP---LPGAGIP------------ 1141
Query: 528 RPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHP 587
P PP P V I P P P P G + P LP G+ P
Sbjct: 1142 ---PPPPLPRVGIP------------PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
Query: 588 HQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP 647
P PLP G+ PPP G PPP L PG+ P+ P P PPP
Sbjct: 1187 ---PPPLPGVGIPPPPPLPGAGIPPPPPL--------PGMGIPPAPAPPLPPPGTGIPPP 1235
Query: 648 PHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSP 680
P L + G T P P P P
Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 46.2 bits (108), Expect = 1e-04
Identities = 78/305 (25%), Positives = 95/305 (31%), Gaps = 97/305 (31%)
Query: 354 LEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA-PPPPDRPIEKKSYSRARRTRT 412
L + P P A + P A PP P A PPPP P
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-------------- 1103
Query: 413 KVGDAVKLAEEVPPPPE----GLIPAPPVPET-TPTPPTKTGTWEAPVDSSTSGLEQDVA 467
VG +PPPP G+ P PP+P P PP G P +
Sbjct: 1104 GVG--------IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--------PPPLP 1147
Query: 468 QLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQ 527
++ I PG P L G G PPP + +G+
Sbjct: 1148 RVGIPPPPPLPGA-GIPPPPPLPGA------GIPPPPP---LPGVGIP------------ 1185
Query: 528 RPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHP 587
P PP P V I P PLP G + P LP G+ P
Sbjct: 1186 ---PPPPLPGVGIP---------------------PPPPLPGAG--IPPPPPLPGMGIPP 1219
Query: 588 HQTPAPLPNPGL-YPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPP 646
P PLP PG PPP + PP + + P V F LPPP
Sbjct: 1220 APAP-PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF-----------LPPPL 1267
Query: 647 PPHLY 651
P L+
Sbjct: 1268 PSGLF 1272
Score = 30.4 bits (67), Expect = 5.9
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
Query: 11 QDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESG--- 67
+D E + G+ G + G +GGG G GGG SG S+ R R+
Sbjct: 30 RDVEATKKGSGGKKALGKHGKGGG---GGGGGGESGKKKSKSDSRASVFSNLRIRKNLSK 86
Query: 68 --GAKSAEESECESE 80
GA + E +S+
Sbjct: 87 GKGAGGSREDVLDSQ 101
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 71.6 bits (174), Expect = 2e-12
Identities = 89/371 (23%), Positives = 126/371 (33%), Gaps = 56/371 (15%)
Query: 340 GETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEE--AASEPPAAAPDAAPPPPDR 397
G T + + L++ + R + +AD V G K + S+PP P PP +
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADI-VRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 398 PIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDS 457
P +KS + + K + P G + P P T PP + P+
Sbjct: 319 PGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQ------PLGP 368
Query: 458 STSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGG 517
+ +Q ++ +EQ PG + QP + P A PP Q ++G
Sbjct: 369 AKPPAQQTGSEKPSSEQ---PGPKALAQPPGVGKTPAQQPGPAKPPTQ-----QVGTPKP 420
Query: 518 RAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
A++ Q P P PV G P Q GP T P P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQ---QPGPGKIPAQQAGPGKTSAQQTGPTKP-------- 469
Query: 578 MNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPY 637
P+ LP P PPP P +PPPQQ P P P
Sbjct: 470 -------------PSQLPGPAK-PPPQQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQ 512
Query: 638 APGALPPPP--PPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTP-----QPVTI 690
PG P P P P +Q P +PA+ Q P +T QP T+
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
Query: 691 KPPPPEVVSRG 701
P + S+G
Sbjct: 573 SPSAKQPPSQG 583
Score = 64.3 bits (155), Expect = 4e-10
Identities = 93/344 (27%), Positives = 125/344 (36%), Gaps = 40/344 (11%)
Query: 355 EQTSVRDPSPEADAPV-LGSPEKEEAASEPPAAAPDAAPPP--PDRPIEKKSYSR-ARRT 410
+Q RDP + P + S + E+ S+PP P P K R A R
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 411 RTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLN 470
+TK D V+ E V P +P+P P P K + + S G +
Sbjct: 282 QTKQADIVR-GESVKPS----LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----- 331
Query: 471 IAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNR-MEEMGVQGGRAKRYSSQRQRP 529
P QPS L + L P + PP + +G A++ S++ P
Sbjct: 332 -------PAQPSGLT-KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK--P 381
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
E P P ++ G P Q GP P+ + QPG+ P P +
Sbjct: 382 SSEQPGPKA-LAQPPGVGKTPAQQPGPAKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTK 438
Query: 590 TPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPH 649
TP P PG P PG+ QQ PT P + P PG P PPP
Sbjct: 439 TPVQQPGPGKIPAQ-QAGPGKTSAQQ-TGPT--KPPSQLPGPAKPPPQQPG--PAKPPPQ 492
Query: 650 LYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPP 693
+ + PSQ G P QQ KPSP QP + KPP
Sbjct: 493 QPGSAKPPSQQPGSTK--PPPQQPGPAKPSP----QQPGSTKPP 530
Score = 40.4 bits (93), Expect = 0.006
Identities = 90/437 (20%), Positives = 137/437 (31%), Gaps = 100/437 (22%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAA----SEPPAAAPDAAPPPPDRPIEKKSYSRARRTR 411
+T V+ P P P K A ++PP+ P A PPP +P K + +
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 412 TKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWE------APVDSSTSGLEQD 465
+ P P P+P P +T P + G+ + +P S +
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 466 VAQLNIAEQNWSPG-QPSFLQPRELRGMPNHI-----------HM--------------- 498
V+Q + P PS QP +G+P I H+
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTT 616
Query: 499 -----GAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPP-----------VHISI 542
G P P ++E + KR PVP P P V S
Sbjct: 617 VCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 543 MEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQP-----------------GMNLPHPGL 585
+ P + P +P P P ++ QP ++ P P
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 586 HP----HQTPAPLPN-----PGLYPPP---VSMSPGQPPPQ------QLLAPTYFSAPGV 627
P Q AP+ + P + P VS S P Q A + P
Sbjct: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
Query: 628 MNFGNPSYPYAPG----------ALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK 677
+ PS + P A+P P + PS G +P Q++ +PK
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 678 PSPPRRTPQPVTIKPPP 694
+ + +P+P KP P
Sbjct: 857 KAQTKMSPKP-DAKPMP 872
Score = 38.9 bits (89), Expect = 0.016
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 26/133 (19%)
Query: 581 PHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLL-------------APTYFSAPGV 627
P P P P P P P PPP S P P ++L A T V
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 628 MNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYN---PAQQQVQPK---PSPP 681
+ PPP PP PS + G+ + + P++ + PK P P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPP-------KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Query: 682 RRTPQPVTIKPPP 694
T +P I P P
Sbjct: 2521 TTTQKPTDIHPKP 2533
Score = 37.4 bits (85), Expect = 0.048
Identities = 61/267 (22%), Positives = 94/267 (35%), Gaps = 34/267 (12%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPA--AAPDAAPPPPDRPIEK-KSYSRARRTRTKVGDAV 418
PS + APV K+ +P + +A PD P K +S + + T D+
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800
Query: 419 KLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSP 478
K ++ PP E + P + P P + + P SS S ++ V + E+
Sbjct: 801 KPSQSFPPTGEKVSPFDS--KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP-KK 857
Query: 479 GQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGR----AKRYS----SQRQRPV 530
Q + + MP GP P + Q + ++R+S S P
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 531 PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPH----PGLH 586
+P P ++ G ++ G S ++ G PH PG
Sbjct: 918 SQPTTPQETVT-------------GKLFGFGASIFS-QASNLISTAGQPGPHSQSGPGAP 963
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPP 613
Q PAP P PP S GQ PP
Sbjct: 964 MKQAPAPSQPPTSQGPP--KSTGQAPP 988
Score = 35.8 bits (81), Expect = 0.14
Identities = 75/383 (19%), Positives = 132/383 (34%), Gaps = 64/383 (16%)
Query: 357 TSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGD 416
T+ S + P SP+K+ A + + AP+ PPP +++ + + + K
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP--LVKQPTLHGSPSAKAKQPP 724
Query: 417 AVKLAEEVPPPPEGLIPA----PPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI- 471
+ PP E +P+ PV + P P V SS++ + D+ +
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 472 --AEQNWSP------GQPS--------FLQPRELRGMP---NHIHMGAGPPPQFNRMEEM 512
AE+ +P +PS + P + + +P + + + P P +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 513 GVQGGRAKRYSSQRQRPV-PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQG 571
V + K + Q + P+P A P+ P P P P P G
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPM-----------PKGSPTP-------PGPRPTAG 886
Query: 572 MLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLL---APTYFSAPGVM 628
V P P + L + P +P + +L A + A ++
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 629 NFGNPSYPYA---PGA-LPPPPPPHLYPNTQAPSQVYGGV------------TYYNPAQQ 672
+ P++ PGA + P P P +Q P + G PA +
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 673 QVQPKPSPPRRTPQPVTIKPPPP 695
+++PK + T K PPP
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPP 1029
Score = 34.7 bits (78), Expect = 0.31
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 376 KEEAASEPPAAAPDAAP-PPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPA 434
+E+ AS+ P+ +P + P RP + S ++ ++ + PPPP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSS-------------SLDISAQPPPPPPPPPPP 2415
Query: 435 PPVPETTPTPPTKTGTWEAP 454
PP P P PP T P
Sbjct: 2416 PPPPPPPPPPPLPPPTSPKP 2435
Score = 33.9 bits (76), Expect = 0.53
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 29/176 (16%)
Query: 491 GMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDP 550
G P+ + A P P F R + + S+Q P P PP PP P
Sbjct: 2379 GSPSVSSLPAKPRPFF-RSSSLDI--------SAQPPPPPPPPPPPPP----------PP 2419
Query: 551 LQFQGPIYTHGDSPAP--LPPQGMLVQPGMNLPHP---GLHPHQTPAPLPNPGLYPPPVS 605
P SP P LP + + V + P + +T A L + GL P
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL--PVTR 2477
Query: 606 MSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVY 661
+ PPP + P S P + F + P P P P P L TQ P+ ++
Sbjct: 2478 ICTTAPPP---VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Score = 33.1 bits (74), Expect = 0.90
Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 15/118 (12%)
Query: 62 RRVESGGAKSAEESECESEDGI--EGDAV---LSDYESAEDSEGEEGEYSEEENSKVELK 116
+R S G+ S++E + E G E D + + + + ED+ G E ++E + +LK
Sbjct: 1528 KRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSE----DDEFIRNQLK 1583
Query: 117 SEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDE 174
++SST+ +K EE K +T + ++S+ ++ G++ H +DDE
Sbjct: 1584 E-----ISSSTESQKKEETKG-KGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDE 1635
Score = 32.3 bits (72), Expect = 1.5
Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 37/100 (37%)
Query: 364 PEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEE 423
P P S + +A PP P PPPP
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------------------------- 2418
Query: 424 VPPPPEGLIPAPPV-PETTPTP---PTKTGTWEAPVDSST 459
PPPP P PP+ P T+P P P K T +PV ++T
Sbjct: 2419 -PPPP----PPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453
Score = 32.3 bits (72), Expect = 1.5
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 35/139 (25%)
Query: 349 YRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRAR 408
+RS L+ ++ P P P P PP P +P P P +K + +
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPP----PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449
Query: 409 RTRTKVGDAV-----------------KLAEEVPPP--------PEGLI----PAPPVPE 439
T T + DAV ++ PPP P GL+ P P P
Sbjct: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP 2509
Query: 440 TTPTP--PTKTGTWEAPVD 456
P P P T + P D
Sbjct: 2510 IAPKPVIPQLPTTTQKPTD 2528
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 71.6 bits (174), Expect = 2e-12
Identities = 89/371 (23%), Positives = 126/371 (33%), Gaps = 56/371 (15%)
Query: 340 GETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEE--AASEPPAAAPDAAPPPPDR 397
G T + + L++ + R + +AD V G K + S+PP P PP +
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADI-VRGESVKPSLPSPSKPPIQQPTPGKPPAQQ 318
Query: 398 PIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDS 457
P +KS + + K + P G + P P T PP + P+
Sbjct: 319 PGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQPPGTTKPPAQ------PLGP 368
Query: 458 STSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGG 517
+ +Q ++ +EQ PG + QP + P A PP Q ++G
Sbjct: 369 AKPPAQQTGSEKPSSEQ---PGPKALAQPPGVGKTPAQQPGPAKPPTQ-----QVGTPKP 420
Query: 518 RAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
A++ Q P P PV G P Q GP T P P
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQ---QPGPGKIPAQQAGPGKTSAQQTGPTKP-------- 469
Query: 578 MNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPY 637
P+ LP P PPP P +PPPQQ P P P
Sbjct: 470 -------------PSQLPGPAK-PPPQQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQ 512
Query: 638 APGALPPPP--PPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTP-----QPVTI 690
PG P P P P +Q P +PA+ Q P +T QP T+
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
Query: 691 KPPPPEVVSRG 701
P + S+G
Sbjct: 573 SPSAKQPPSQG 583
Score = 64.3 bits (155), Expect = 4e-10
Identities = 93/344 (27%), Positives = 125/344 (36%), Gaps = 40/344 (11%)
Query: 355 EQTSVRDPSPEADAPV-LGSPEKEEAASEPPAAAPDAAPPP--PDRPIEKKSYSR-ARRT 410
+Q RDP + P + S + E+ S+PP P P K R A R
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 411 RTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLN 470
+TK D V+ E V P +P+P P P K + + S G +
Sbjct: 282 QTKQADIVR-GESVKPS----LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----- 331
Query: 471 IAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNR-MEEMGVQGGRAKRYSSQRQRP 529
P QPS L + L P + PP + +G A++ S++ P
Sbjct: 332 -------PAQPSGLT-KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK--P 381
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
E P P ++ G P Q GP P+ + QPG+ P P +
Sbjct: 382 SSEQPGPKA-LAQPPGVGKTPAQQPGPAKPPTQQVGT--PKPLAQQPGLQSPAKAPGPTK 438
Query: 590 TPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPH 649
TP P PG P PG+ QQ PT P + P PG P PPP
Sbjct: 439 TPVQQPGPGKIPAQ-QAGPGKTSAQQ-TGPT--KPPSQLPGPAKPPPQQPG--PAKPPPQ 492
Query: 650 LYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPP 693
+ + PSQ G P QQ KPSP QP + KPP
Sbjct: 493 QPGSAKPPSQQPGSTK--PPPQQPGPAKPSP----QQPGSTKPP 530
Score = 40.4 bits (93), Expect = 0.006
Identities = 90/437 (20%), Positives = 137/437 (31%), Gaps = 100/437 (22%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAA----SEPPAAAPDAAPPPPDRPIEKKSYSRARRTR 411
+T V+ P P P K A ++PP+ P A PPP +P K + +
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 412 TKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWE------APVDSSTSGLEQD 465
+ P P P+P P +T P + G+ + +P S +
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 466 VAQLNIAEQNWSPG-QPSFLQPRELRGMPNHI-----------HM--------------- 498
V+Q + P PS QP +G+P I H+
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPS-QGLPKTICPLCNTTELLLHVPEKANFNTCTECQTT 616
Query: 499 -----GAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPP-----------VHISI 542
G P P ++E + KR PVP P P V S
Sbjct: 617 VCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 543 MEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQP-----------------GMNLPHPGL 585
+ P + P +P P P ++ QP ++ P P
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
Query: 586 HP----HQTPAPLPN-----PGLYPPP---VSMSPGQPPPQ------QLLAPTYFSAPGV 627
P Q AP+ + P + P VS S P Q A + P
Sbjct: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
Query: 628 MNFGNPSYPYAPG----------ALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK 677
+ PS + P A+P P + PS G +P Q++ +PK
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 678 PSPPRRTPQPVTIKPPP 694
+ + +P+P KP P
Sbjct: 857 KAQTKMSPKP-DAKPMP 872
Score = 38.9 bits (89), Expect = 0.016
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 26/133 (19%)
Query: 581 PHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLL-------------APTYFSAPGV 627
P P P P P P P PPP S P P ++L A T V
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 628 MNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYN---PAQQQVQPK---PSPP 681
+ PPP PP PS + G+ + + P++ + PK P P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPP-------KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Query: 682 RRTPQPVTIKPPP 694
T +P I P P
Sbjct: 2521 TTTQKPTDIHPKP 2533
Score = 37.4 bits (85), Expect = 0.048
Identities = 61/267 (22%), Positives = 94/267 (35%), Gaps = 34/267 (12%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPA--AAPDAAPPPPDRPIEK-KSYSRARRTRTKVGDAV 418
PS + APV K+ +P + +A PD P K +S + + T D+
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800
Query: 419 KLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSP 478
K ++ PP E + P + P P + + P SS S ++ V + E+
Sbjct: 801 KPSQSFPPTGEKVSPFDS--KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP-KK 857
Query: 479 GQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGR----AKRYS----SQRQRPV 530
Q + + MP GP P + Q + ++R+S S P
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 531 PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPH----PGLH 586
+P P ++ G ++ G S ++ G PH PG
Sbjct: 918 SQPTTPQETVT-------------GKLFGFGASIFS-QASNLISTAGQPGPHSQSGPGAP 963
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPP 613
Q PAP P PP S GQ PP
Sbjct: 964 MKQAPAPSQPPTSQGPP--KSTGQAPP 988
Score = 35.8 bits (81), Expect = 0.14
Identities = 75/383 (19%), Positives = 132/383 (34%), Gaps = 64/383 (16%)
Query: 357 TSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGD 416
T+ S + P SP+K+ A + + AP+ PPP +++ + + + K
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP--LVKQPTLHGSPSAKAKQPP 724
Query: 417 AVKLAEEVPPPPEGLIPA----PPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI- 471
+ PP E +P+ PV + P P V SS++ + D+ +
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 472 --AEQNWSP------GQPS--------FLQPRELRGMP---NHIHMGAGPPPQFNRMEEM 512
AE+ +P +PS + P + + +P + + + P P +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 513 GVQGGRAKRYSSQRQRPV-PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQG 571
V + K + Q + P+P A P+ P P P P P G
Sbjct: 845 QVDPVQKKEEPKKAQTKMSPKPDAKPM-----------PKGSPTP-------PGPRPTAG 886
Query: 572 MLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLL---APTYFSAPGVM 628
V P P + L + P +P + +L A + A ++
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
Query: 629 NFGNPSYPYA---PGA-LPPPPPPHLYPNTQAPSQVYGGV------------TYYNPAQQ 672
+ P++ PGA + P P P +Q P + G PA +
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 673 QVQPKPSPPRRTPQPVTIKPPPP 695
+++PK + T K PPP
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPP 1029
Score = 34.7 bits (78), Expect = 0.31
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 376 KEEAASEPPAAAPDAAP-PPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPA 434
+E+ AS+ P+ +P + P RP + S ++ ++ + PPPP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSS-------------SLDISAQPPPPPPPPPPP 2415
Query: 435 PPVPETTPTPPTKTGTWEAP 454
PP P P PP T P
Sbjct: 2416 PPPPPPPPPPPLPPPTSPKP 2435
Score = 33.9 bits (76), Expect = 0.53
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 29/176 (16%)
Query: 491 GMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDP 550
G P+ + A P P F R + + S+Q P P PP PP P
Sbjct: 2379 GSPSVSSLPAKPRPFF-RSSSLDI--------SAQPPPPPPPPPPPPP----------PP 2419
Query: 551 LQFQGPIYTHGDSPAP--LPPQGMLVQPGMNLPHP---GLHPHQTPAPLPNPGLYPPPVS 605
P SP P LP + + V + P + +T A L + GL P
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL--PVTR 2477
Query: 606 MSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVY 661
+ PPP + P S P + F + P P P P P L TQ P+ ++
Sbjct: 2478 ICTTAPPP---VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Score = 33.1 bits (74), Expect = 0.90
Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 15/118 (12%)
Query: 62 RRVESGGAKSAEESECESEDGI--EGDAV---LSDYESAEDSEGEEGEYSEEENSKVELK 116
+R S G+ S++E + E G E D + + + + ED+ G E ++E + +LK
Sbjct: 1528 KRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSE----DDEFIRNQLK 1583
Query: 117 SEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDE 174
++SST+ +K EE K +T + ++S+ ++ G++ H +DDE
Sbjct: 1584 E-----ISSSTESQKKEETKG-KGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDE 1635
Score = 32.3 bits (72), Expect = 1.5
Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 37/100 (37%)
Query: 364 PEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEE 423
P P S + +A PP P PPPP
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---------------------------- 2418
Query: 424 VPPPPEGLIPAPPV-PETTPTP---PTKTGTWEAPVDSST 459
PPPP P PP+ P T+P P P K T +PV ++T
Sbjct: 2419 -PPPP----PPPPLPPPTSPKPTILPKKKLTVASPVTTAT 2453
Score = 32.3 bits (72), Expect = 1.5
Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 35/139 (25%)
Query: 349 YRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRAR 408
+RS L+ ++ P P P P PP P +P P P +K + +
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPP----PPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449
Query: 409 RTRTKVGDAV-----------------KLAEEVPPP--------PEGLI----PAPPVPE 439
T T + DAV ++ PPP P GL+ P P P
Sbjct: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP 2509
Query: 440 TTPTP--PTKTGTWEAPVD 456
P P P T + P D
Sbjct: 2510 IAPKPVIPQLPTTTQKPTD 2528
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 71.6 bits (174), Expect = 2e-12
Identities = 101/402 (25%), Positives = 144/402 (35%), Gaps = 83/402 (20%)
Query: 338 RSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPD- 396
R+ T + + R + L++ + P P AP P +EE + A +A PP +
Sbjct: 692 RTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREE------SEAVEAGDPPEEL 745
Query: 397 RPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAP-----PVPETTPTPPTKTGTW 451
R + + R T +G A L P P P P P+P T + PT+
Sbjct: 746 RSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQP 805
Query: 452 EAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAG---------- 501
AP + ++P + G+ + ++G G
Sbjct: 806 RAP---GPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPS 862
Query: 502 -PPPQFNRME-EMGVQGGRA---------KRYSSQRQRPVPEPPAPPVHI---SIMEGHY 547
PPPQF+ E M V+ +++ R P P PP P + + Y
Sbjct: 863 APPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPY 922
Query: 548 YDPLQFQGPI----YTHGDSPAPLPPQGMLVQPGMN-LPHP----GLHPHQTPAPLPNPG 598
P + PI + PA P + QP + PHP G P Q P PL +P
Sbjct: 923 TYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPH 982
Query: 599 LYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYA--PGALPPPPPP---HLYPN 653
L+PP +PG PPQ YPYA PG L PPPP LYP
Sbjct: 983 LFPP---QAPGLLPPQS------------------PYPYAPQPGVLGQPPPPLHTQLYPG 1021
Query: 654 -TQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
Q P + G + P P PP+ P+ P P
Sbjct: 1022 PAQDPLPAHSGALPF--------PSPGPPQPPHPPLAYGPAP 1055
Score = 54.3 bits (129), Expect = 4e-07
Identities = 68/282 (24%), Positives = 97/282 (34%), Gaps = 54/282 (19%)
Query: 370 VLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLA-------- 421
V+ SP + P A P A PP P + A R T D+++
Sbjct: 843 VVSSPYVGVGPAPPVAGLPSAPPPQFSGP----ELAMAVRPATTTVDSIQAPIPSHTAPR 898
Query: 422 -EEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSS---TSGLEQDVAQLNIAEQNWS 477
P PP P PP P+ PTP T + P+ + +SG+ I Q
Sbjct: 899 PNPTPAPPPPCFPVPP-PQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQP 957
Query: 478 PGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRA-------KRYSSQRQRPV 530
QP Q G PP Q ++ + +A Y Q V
Sbjct: 958 HPQPHPSQA-----------FGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGV 1006
Query: 531 PEPPAPPVHISIMEGHYYDPL---------------QFQGPIYTHGDSPA--PLPPQG-- 571
P PP+H + G DPL Q P +G +P+ P+ PQ
Sbjct: 1007 LGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAP 1066
Query: 572 MLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPP 613
+ ++ + PH P+P P+PG P P +PPP
Sbjct: 1067 LTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPP 1108
Score = 34.3 bits (77), Expect = 0.41
Identities = 36/130 (27%), Positives = 46/130 (35%), Gaps = 33/130 (25%)
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAP----------LPPQGMLVQPGMN 579
VP P P SI + ++ Q + GD P + P G L P +
Sbjct: 1462 VPPPCKPLASASISQKNHLP--QDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVAS 1519
Query: 580 LPHP----GLHPHQTPAPLPNPGLYPPPVSMS-PGQPPPQQLLAPTYFSAPGVMNFGNPS 634
LP P GL P P P P PPP+S P P P++ P
Sbjct: 1520 LPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKE----------------EPP 1563
Query: 635 YPYAPGALPP 644
P AP + PP
Sbjct: 1564 VPEAPSSGPP 1573
Score = 31.6 bits (70), Expect = 2.6
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Query: 347 ISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSR 406
IS + + S+R P ++PV P E PPA+ P++ P P P S
Sbjct: 1495 ISSIQATIAKLSIRPPGG-LESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSS--- 1550
Query: 407 ARRTRTKVGDAVKLAEEVPPPPEGLIPAPP 436
+ +A + EE PP PE PP
Sbjct: 1551 ------PLPEAPQPKEE-PPVPEAPSSGPP 1573
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 70.5 bits (171), Expect = 5e-12
Identities = 93/332 (28%), Positives = 120/332 (36%), Gaps = 81/332 (24%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVG 415
Q S S E P P+ + A + PA P P P P + K R
Sbjct: 289 QQSQPSQSSEPSQPQQKDPQ-QPAQQQQPAQQPKKPSPQPSSPRQVK-----RAVVVSPK 342
Query: 416 DAVKLAEEVPPPPEGLIPA-----PPVPETTPTP----PTKTGTWEA----PVDSSTSGL 462
+ K AE PPPP+ IP PP+P P P P EA PVD++
Sbjct: 343 EENKAAE--PPPPK--IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDAT---- 394
Query: 463 EQDVAQLNIAEQNWSPGQPSFL-QPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGG--RA 519
D+ ++ I P P+ + QP L P PPP + M M
Sbjct: 395 --DLPKVQIPP----PAHPAPVHQPPPLPHRPP-------PPPPSSYMTGMSTTSSYMSG 441
Query: 520 KRYSSQRQRPVPE-------PPA--PPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQ 570
+ Y S + E PPA PP H L + +Y P P+PP
Sbjct: 442 EGYQSLQSMMKTEGPSYGALPPAYGPPAH-----------LPYHPHVYPPNPPPPPVPP- 489
Query: 571 GMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAP-GVMN 629
P + P P + P P PG PPP + +P PPP L PT+ P
Sbjct: 490 -----PPASFPPPAIPP-------PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
Query: 630 FGNPSYPYAPGALP----PPPPPHLYPNTQAP 657
G P Y P A+P PP PP + P P
Sbjct: 538 LGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 60.5 bits (145), Expect = 5e-09
Identities = 76/295 (25%), Positives = 101/295 (34%), Gaps = 62/295 (21%)
Query: 428 PEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPG-QPSFLQP 486
P L P P VP+ + P+++ P +Q Q A+Q P QPS P
Sbjct: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDP---QQPAQQQQPAQQPKKPSPQPS--SP 330
Query: 487 RELRGM----PNHIHMGAGPPP-QFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHIS 541
R+++ P + A PPP + ++E PP PP H
Sbjct: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIE-------------------TTHPPLPPAH-- 369
Query: 542 IMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHP---HQTPAPLPNPG 598
P + P+ P P P + +P P HP HQ P PLP+
Sbjct: 370 -------PPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-HPAPVHQPP-PLPHRP 420
Query: 599 LYPPPVSMSPGQPPPQQLLAPT-YFSAPGVMNFGNPSY-------------PYAPGALPP 644
PPP S G ++ Y S +M PSY PY P PP
Sbjct: 421 PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPP 480
Query: 645 PPPP---HLYPNTQAPSQVYGGVTYYNPAQQQVQPK-PSPPRRTPQPVTIKPPPP 695
PPP P + P + Y P P P PP R P + P PP
Sbjct: 481 NPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP 535
Score = 37.7 bits (86), Expect = 0.037
Identities = 34/116 (29%), Positives = 44/116 (37%), Gaps = 14/116 (12%)
Query: 587 PHQTPAPLPNP-GLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPP 645
PH TP L P L P P Q P Q P+ S P +P P A P
Sbjct: 266 PHHTPHQLQQPPSLQPTP------QVPQVQQSQPSQSSEPSQPQQKDPQQP-AQQQQPAQ 318
Query: 646 PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPR-----RTPQPVTIKPPPPE 696
P P +P QV V +P ++ +P PP+ T P+ PPP+
Sbjct: 319 QPKKPSPQPSSPRQVKRAVVV-SPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPD 373
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 67.0 bits (162), Expect = 6e-11
Identities = 108/456 (23%), Positives = 160/456 (35%), Gaps = 65/456 (14%)
Query: 271 PNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPR-NYSRSGGFKEGRAGFRPV 329
P+ +N+ R G T N + A T + SA + S K + V
Sbjct: 41 PDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKV 100
Query: 330 EAGGQHGGR--SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAA 387
+ + R S +T EIS + E S + GS + ++ + + +
Sbjct: 101 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTS 158
Query: 388 PDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTP-PT 446
P + P P D + S ++ + + + A++ V P P APP PTP PT
Sbjct: 159 P-SIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAPSS---APPGTPQLPTPGPT 213
Query: 447 KTGTWEAPVDSSTSGLEQDVAQLNIAE-QNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQ 505
+ T P S T+ + Q A + Q L P+ P H PPP
Sbjct: 214 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR----PPSPH----PPPH 265
Query: 506 FNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPA 565
+ + G A + S+ P PP+H G + LQ GP+ H P
Sbjct: 266 PSPHPPLQPLTGSAGQPSA------PSHAQPPLHGQGPPGPH--SLQ-AGPLLQHPGPPQ 316
Query: 566 P--LPPQGMLVQPGMNLPHPGLHPHQT----------------------PAPLPNPGLYP 601
P LPPQ Q + +PH + PAPL P + P
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 376
Query: 602 PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP---PHLYPNTQAPS 658
PP + P P PQ P + S P P++ A PPPP P +T P
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPS---------PFSMNANLPPPPALKPLSSLSTHHPP 427
Query: 659 QVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
+ P Q + P+ P Q + PPP
Sbjct: 428 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463
Score = 60.1 bits (144), Expect = 7e-09
Identities = 92/401 (22%), Positives = 132/401 (32%), Gaps = 111/401 (27%)
Query: 362 PSPEADA-PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P+P A A P GSP +A ++P A AP P T + A L
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPT---APVP----------------HTHIQQAPAL 252
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDV----------AQLN 470
+ PP P P P +P PP + T A S+ S + + Q
Sbjct: 253 HPQRPPSPH------PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306
Query: 471 IAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPV 530
Q+ P QP L P+ +G +G P + + + ++ S Q R
Sbjct: 307 PLLQHPGPPQPFGLPPQASQGQAP---LGTSPAAAYPHTS-LQLPASQSALQSQQPPREQ 362
Query: 531 PEPPAP------------PV-HISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
P PPAP P+ + + H + P H P+P L P
Sbjct: 363 PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP---------HLSGPSPFSMNANLPPPP 413
Query: 578 MNLPHPGLHPHQTPA-------------PLPNPGLYPPPVSMSPGQPPPQQLLAPT--YF 622
P L H P+ PLP+ PP ++ S PPP PT +
Sbjct: 414 ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473
Query: 623 SAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAP-------------------SQVYGG 663
AP +P+ PG PPP P P+T P + GG
Sbjct: 474 VAP---QPPFAQHPFVPGG-PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 529
Query: 664 VTYYNP-----------AQQQVQPKPSPPRRTPQPVTIKPP 693
+ P A++ P P P +P+P + P
Sbjct: 530 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570
Score = 48.5 bits (114), Expect = 2e-05
Identities = 134/643 (20%), Positives = 210/643 (32%), Gaps = 93/643 (14%)
Query: 14 EDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAE 73
++E+ G SG S + G S S G P+ GRT ++ + S G S
Sbjct: 6 KEEDDGLSGKHSMRTRRSRG---SMSTLRSGRKKQPASPDGRTSPIN-EDIRSSGRNSPS 61
Query: 74 ESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGE 133
+ S D + + V + ++ + ++ + KV S+ +A +S+K+ K +
Sbjct: 62 AASTSSNDS-KAETVKKSAKKVKEEASSPLKSNKRQREKVA--SDTEEADRTSSKKTKTQ 118
Query: 134 EKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDL 193
E S GE +S D + N G PK +D D +P+ + + D
Sbjct: 119 EISRPNSPSEGEGESSDSRSV-----NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 173
Query: 194 RGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDI 253
Q Q + +P Q P A+ +A +
Sbjct: 174 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN- 232
Query: 254 KPRRIRKPRYGSPPQRDPNWNGERLNKSH--RHQGLGGTLPPRTFINRNAAGTGRMSAPR 311
+P+ P + Q+ P + +R H H L P T G+ SAP
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT------GSAGQPSAP- 285
Query: 312 NYSRSGGFKEGRAGFRPVEAGG--QHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAP 369
++++ +G G ++AG QH G P P
Sbjct: 286 SHAQPPLHGQGPPGPHSLQAGPLLQHPG-----------------------PPQP----- 317
Query: 370 VLGSPEKEEAASEPPAAAPDAAPPPP--DRPIEKKSYSRARRTRTKVGDAVKLA-EEVPP 426
G P + P +P AA P P + + + R + LA + P
Sbjct: 318 -FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 376
Query: 427 PPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQP 486
PP IP P P+ PP +G +++ N P P L+P
Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-----------------NLPP--PPALKP 417
Query: 487 RELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPA--PPVHISIME 544
L + H A PPP + + A+ + + +P PPA PP +
Sbjct: 418 --LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL---- 471
Query: 545 GHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPV 604
H P Q P H P PP P + P G T A P G
Sbjct: 472 -HQVAP---QPPFAQHPFVPGGPPPITPPTCPSTSTPPAG---PGTSAQPPCSGAAASGG 524
Query: 605 SMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP 647
S++ G P L + + P P P P P P
Sbjct: 525 SIAGGSSCP---LPTVQIKEEALDDAEEPESPPPPPRSPSPEP 564
Score = 37.0 bits (84), Expect = 0.063
Identities = 45/153 (29%), Positives = 61/153 (39%), Gaps = 31/153 (20%)
Query: 500 AGPP--PQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP---APPVHISIMEGHYYDPLQFQ 554
AGP P+ + + + + A+R +S P+ P H H + L Q
Sbjct: 828 AGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQ 887
Query: 555 GPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQ 614
P+ H S P+ P LV P PH P+ P LPNP L GQPP +
Sbjct: 888 DPL--HQGSAGPVHP---LVDPLTAGPHLARFPYP-PGTLPNPLL---------GQPPHE 932
Query: 615 -QLLAPTYFSAPGVMNFGNPSYPY-APGALPPP 645
++L F P YP PGA+PPP
Sbjct: 933 HEMLRHPVFGTP---------YPRDLPGAIPPP 956
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 546 HYYDPLQ--FQGPIYTHGDSPAPLPPQGMLVQPGMNLPHP--GLHPHQ----------TP 591
H DPL GP++ D P P LP+P G PH+ TP
Sbjct: 885 HQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTP 944
Query: 592 APLPNPGLYPPPVS 605
P PG PPP+S
Sbjct: 945 YPRDLPGAIPPPMS 958
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 67.0 bits (162), Expect = 6e-11
Identities = 108/456 (23%), Positives = 160/456 (35%), Gaps = 65/456 (14%)
Query: 271 PNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPR-NYSRSGGFKEGRAGFRPV 329
P+ +N+ R G T N + A T + SA + S K + V
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 330 EAGGQHGGR--SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAA 387
+ + R S +T EIS + E S + GS + ++ + + +
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTS 712
Query: 388 PDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTP-PT 446
P + P P D + S ++ + + + A++ V P P APP PTP PT
Sbjct: 713 P-SIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAPSS---APPGTPQLPTPGPT 767
Query: 447 KTGTWEAPVDSSTSGLEQDVAQLNIAE-QNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQ 505
+ T P S T+ + Q A + Q L P+ P H PPP
Sbjct: 768 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR----PPSPH----PPPH 819
Query: 506 FNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPA 565
+ + G A + S+ P PP+H G + LQ GP+ H P
Sbjct: 820 PSPHPPLQPLTGSAGQPSA------PSHAQPPLHGQGPPGPH--SLQ-AGPLLQHPGPPQ 870
Query: 566 P--LPPQGMLVQPGMNLPHPGLHPHQT----------------------PAPLPNPGLYP 601
P LPPQ Q + +PH + PAPL P + P
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 602 PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP---PHLYPNTQAPS 658
PP + P P PQ P + S P P++ A PPPP P +T P
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPS---------PFSMNANLPPPPALKPLSSLSTHHPP 981
Query: 659 QVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
+ P Q + P+ P Q + PPP
Sbjct: 982 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
Score = 60.1 bits (144), Expect = 7e-09
Identities = 92/401 (22%), Positives = 132/401 (32%), Gaps = 111/401 (27%)
Query: 362 PSPEADA-PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P+P A A P GSP +A ++P A AP P T + A L
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPT---APVP----------------HTHIQQAPAL 806
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDV----------AQLN 470
+ PP P P P +P PP + T A S+ S + + Q
Sbjct: 807 HPQRPPSPH------PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860
Query: 471 IAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPV 530
Q+ P QP L P+ +G +G P + + + ++ S Q R
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAP---LGTSPAAAYPHTS-LQLPASQSALQSQQPPREQ 916
Query: 531 PEPPAP------------PV-HISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
P PPAP P+ + + H + P H P+P L P
Sbjct: 917 PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP---------HLSGPSPFSMNANLPPPP 967
Query: 578 MNLPHPGLHPHQTPA-------------PLPNPGLYPPPVSMSPGQPPPQQLLAPT--YF 622
P L H P+ PLP+ PP ++ S PPP PT +
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027
Query: 623 SAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAP-------------------SQVYGG 663
AP +P+ PG PPP P P+T P + GG
Sbjct: 1028 VAP---QPPFAQHPFVPGG-PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 664 VTYYNP-----------AQQQVQPKPSPPRRTPQPVTIKPP 693
+ P A++ P P P +P+P + P
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 48.5 bits (114), Expect = 2e-05
Identities = 134/643 (20%), Positives = 210/643 (32%), Gaps = 93/643 (14%)
Query: 14 EDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAE 73
++E+ G SG S + G S S G P+ GRT ++ + S G S
Sbjct: 560 KEEDDGLSGKHSMRTRRSRG---SMSTLRSGRKKQPASPDGRTSPIN-EDIRSSGRNSPS 615
Query: 74 ESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGE 133
+ S D + + V + ++ + ++ + KV S+ +A +S+K+ K +
Sbjct: 616 AASTSSNDS-KAETVKKSAKKVKEEASSPLKSNKRQREKVA--SDTEEADRTSSKKTKTQ 672
Query: 134 EKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDL 193
E S GE +S D + N G PK +D D +P+ + + D
Sbjct: 673 EISRPNSPSEGEGESSDSRSV-----NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 727
Query: 194 RGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDI 253
Q Q + +P Q P A+ +A +
Sbjct: 728 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN- 786
Query: 254 KPRRIRKPRYGSPPQRDPNWNGERLNKSH--RHQGLGGTLPPRTFINRNAAGTGRMSAPR 311
+P+ P + Q+ P + +R H H L P T G+ SAP
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT------GSAGQPSAP- 839
Query: 312 NYSRSGGFKEGRAGFRPVEAGG--QHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAP 369
++++ +G G ++AG QH G P P
Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPG-----------------------PPQP----- 871
Query: 370 VLGSPEKEEAASEPPAAAPDAAPPPP--DRPIEKKSYSRARRTRTKVGDAVKLA-EEVPP 426
G P + P +P AA P P + + + R + LA + P
Sbjct: 872 -FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 427 PPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQP 486
PP IP P P+ PP +G +++ N P P L+P
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-----------------NLPP--PPALKP 971
Query: 487 RELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPA--PPVHISIME 544
L + H A PPP + + A+ + + +P PPA PP +
Sbjct: 972 --LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL---- 1025
Query: 545 GHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPV 604
H P Q P H P PP P + P G T A P G
Sbjct: 1026 -HQVAP---QPPFAQHPFVPGGPPPITPPTCPSTSTPPAG---PGTSAQPPCSGAAASGG 1078
Query: 605 SMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP 647
S++ G P L + + P P P P P P
Sbjct: 1079 SIAGGSSCP---LPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118
Score = 37.0 bits (84), Expect = 0.063
Identities = 45/153 (29%), Positives = 61/153 (39%), Gaps = 31/153 (20%)
Query: 500 AGPP--PQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP---APPVHISIMEGHYYDPLQFQ 554
AGP P+ + + + + A+R +S P+ P H H + L Q
Sbjct: 1382 AGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQ 1441
Query: 555 GPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQ 614
P+ H S P+ P LV P PH P+ P LPNP L GQPP +
Sbjct: 1442 DPL--HQGSAGPVHP---LVDPLTAGPHLARFPYP-PGTLPNPLL---------GQPPHE 1486
Query: 615 -QLLAPTYFSAPGVMNFGNPSYPY-APGALPPP 645
++L F P YP PGA+PPP
Sbjct: 1487 HEMLRHPVFGTP---------YPRDLPGAIPPP 1510
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 546 HYYDPLQ--FQGPIYTHGDSPAPLPPQGMLVQPGMNLPHP--GLHPHQ----------TP 591
H DPL GP++ D P P LP+P G PH+ TP
Sbjct: 1439 HQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTP 1498
Query: 592 APLPNPGLYPPPVS 605
P PG PPP+S
Sbjct: 1499 YPRDLPGAIPPPMS 1512
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 67.0 bits (162), Expect = 6e-11
Identities = 108/456 (23%), Positives = 160/456 (35%), Gaps = 65/456 (14%)
Query: 271 PNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPR-NYSRSGGFKEGRAGFRPV 329
P+ +N+ R G T N + A T + SA + S K + V
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 330 EAGGQHGGR--SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAA 387
+ + R S +T EIS + E S + GS + ++ + + +
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDIDQDNRSTS 712
Query: 388 PDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTP-PT 446
P + P P D + S ++ + + + A++ V P P APP PTP PT
Sbjct: 713 P-SIPSPQDNESDSDSSAQQQMLQAQP-PALQAPTGVTPAPSS---APPGTPQLPTPGPT 767
Query: 447 KTGTWEAPVDSSTSGLEQDVAQLNIAE-QNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQ 505
+ T P S T+ + Q A + Q L P+ P H PPP
Sbjct: 768 PSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR----PPSPH----PPPH 819
Query: 506 FNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPA 565
+ + G A + S+ P PP+H G + LQ GP+ H P
Sbjct: 820 PSPHPPLQPLTGSAGQPSA------PSHAQPPLHGQGPPGPH--SLQ-AGPLLQHPGPPQ 870
Query: 566 P--LPPQGMLVQPGMNLPHPGLHPHQT----------------------PAPLPNPGLYP 601
P LPPQ Q + +PH + PAPL P + P
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 602 PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP---PHLYPNTQAPS 658
PP + P P PQ P + S P P++ A PPPP P +T P
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPS---------PFSMNANLPPPPALKPLSSLSTHHPP 981
Query: 659 QVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
+ P Q + P+ P Q + PPP
Sbjct: 982 SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017
Score = 60.1 bits (144), Expect = 7e-09
Identities = 92/401 (22%), Positives = 132/401 (32%), Gaps = 111/401 (27%)
Query: 362 PSPEADA-PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P+P A A P GSP +A ++P A AP P T + A L
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPT---APVP----------------HTHIQQAPAL 806
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDV----------AQLN 470
+ PP P P P +P PP + T A S+ S + + Q
Sbjct: 807 HPQRPPSPH------PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860
Query: 471 IAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPV 530
Q+ P QP L P+ +G +G P + + + ++ S Q R
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAP---LGTSPAAAYPHTS-LQLPASQSALQSQQPPREQ 916
Query: 531 PEPPAP------------PV-HISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
P PPAP P+ + + H + P H P+P L P
Sbjct: 917 PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP---------HLSGPSPFSMNANLPPPP 967
Query: 578 MNLPHPGLHPHQTPA-------------PLPNPGLYPPPVSMSPGQPPPQQLLAPT--YF 622
P L H P+ PLP+ PP ++ S PPP PT +
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027
Query: 623 SAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAP-------------------SQVYGG 663
AP +P+ PG PPP P P+T P + GG
Sbjct: 1028 VAP---QPPFAQHPFVPGG-PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 664 VTYYNP-----------AQQQVQPKPSPPRRTPQPVTIKPP 693
+ P A++ P P P +P+P + P
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124
Score = 48.5 bits (114), Expect = 2e-05
Identities = 134/643 (20%), Positives = 210/643 (32%), Gaps = 93/643 (14%)
Query: 14 EDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAE 73
++E+ G SG S + G S S G P+ GRT ++ + S G S
Sbjct: 560 KEEDDGLSGKHSMRTRRSRG---SMSTLRSGRKKQPASPDGRTSPIN-EDIRSSGRNSPS 615
Query: 74 ESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGE 133
+ S D + + V + ++ + ++ + KV S+ +A +S+K+ K +
Sbjct: 616 AASTSSNDS-KAETVKKSAKKVKEEASSPLKSNKRQREKVA--SDTEEADRTSSKKTKTQ 672
Query: 134 EKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDL 193
E S GE +S D + N G PK +D D +P+ + + D
Sbjct: 673 EISRPNSPSEGEGESSDSRSV-----NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 727
Query: 194 RGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDI 253
Q Q + +P Q P A+ +A +
Sbjct: 728 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN- 786
Query: 254 KPRRIRKPRYGSPPQRDPNWNGERLNKSH--RHQGLGGTLPPRTFINRNAAGTGRMSAPR 311
+P+ P + Q+ P + +R H H L P T G+ SAP
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT------GSAGQPSAP- 839
Query: 312 NYSRSGGFKEGRAGFRPVEAGG--QHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAP 369
++++ +G G ++AG QH G P P
Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPG-----------------------PPQP----- 871
Query: 370 VLGSPEKEEAASEPPAAAPDAAPPPP--DRPIEKKSYSRARRTRTKVGDAVKLA-EEVPP 426
G P + P +P AA P P + + + R + LA + P
Sbjct: 872 -FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP 930
Query: 427 PPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQP 486
PP IP P P+ PP +G +++ N P P L+P
Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA-----------------NLPP--PPALKP 971
Query: 487 RELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPA--PPVHISIME 544
L + H A PPP + + A+ + + +P PPA PP +
Sbjct: 972 --LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGL---- 1025
Query: 545 GHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPV 604
H P Q P H P PP P + P G T A P G
Sbjct: 1026 -HQVAP---QPPFAQHPFVPGGPPPITPPTCPSTSTPPAG---PGTSAQPPCSGAAASGG 1078
Query: 605 SMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP 647
S++ G P L + + P P P P P P
Sbjct: 1079 SIAGGSSCP---LPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118
Score = 37.0 bits (84), Expect = 0.063
Identities = 45/153 (29%), Positives = 61/153 (39%), Gaps = 31/153 (20%)
Query: 500 AGPP--PQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP---APPVHISIMEGHYYDPLQFQ 554
AGP P+ + + + + A+R +S P+ P H H + L Q
Sbjct: 1382 AGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQ 1441
Query: 555 GPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQ 614
P+ H S P+ P LV P PH P+ P LPNP L GQPP +
Sbjct: 1442 DPL--HQGSAGPVHP---LVDPLTAGPHLARFPYP-PGTLPNPLL---------GQPPHE 1486
Query: 615 -QLLAPTYFSAPGVMNFGNPSYPY-APGALPPP 645
++L F P YP PGA+PPP
Sbjct: 1487 HEMLRHPVFGTP---------YPRDLPGAIPPP 1510
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 14/74 (18%)
Query: 546 HYYDPLQ--FQGPIYTHGDSPAPLPPQGMLVQPGMNLPHP--GLHPHQ----------TP 591
H DPL GP++ D P P LP+P G PH+ TP
Sbjct: 1439 HQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTP 1498
Query: 592 APLPNPGLYPPPVS 605
P PG PPP+S
Sbjct: 1499 YPRDLPGAIPPPMS 1512
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 66.6 bits (161), Expect = 7e-11
Identities = 144/665 (21%), Positives = 221/665 (33%), Gaps = 107/665 (16%)
Query: 90 SDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNS--STKEEKGEEKPDTKSTVTGERQ 147
S +S+ DS+ + EE ++ E AV+ + + + KP K E++
Sbjct: 488 SSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKK 547
Query: 148 SGDGQESTEPVENKVGK---------KGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQ 198
+ E ENK K K + + +K PA + K +
Sbjct: 548 KEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSK----PPPTYESEE 603
Query: 199 EEEVRPKG--RQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDI--- 253
E++ +P +R+L D + +K +SR+ + NPD+I
Sbjct: 604 EDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSL--------KNSNPDEIEID 655
Query: 254 ----KPRRIRK-PRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMS 308
KP +R+ RY + R +R ++ + + G+ + F + + + S
Sbjct: 656 FETLKPSTLRELERYVTSCLRK-----KRKPQAEKVDVIAGSSKMKGFSSSESESSSESS 710
Query: 309 APRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADA 368
S ++ P H GR + H + ++ + P P
Sbjct: 711 -------SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQ 763
Query: 369 PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPP- 427
P P +++ PP PPPP P + ++ L ++P
Sbjct: 764 PPPPPPPQQQQQPPPP-------PPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSV 816
Query: 428 --PEGLIPAP----PVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQP 481
P G P P PE P P + P S+ L Q A N P QP
Sbjct: 817 FDPIGHFTQPILHLPQPELPPHLP------QPPEHSTPPHLNQHAVVSPPALHNALPQQP 870
Query: 482 SFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHIS 541
S R P A PP + + + Q EPPAPP+
Sbjct: 871 SRPSNRAAALPPKP----ARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSM 926
Query: 542 IMEGHYYDPLQFQGP------IYTHGDSPAPLPP------QGMLVQ--PGMNLPHPGLHP 587
M+ + + Q P + P PLPP Q L Q P P P P
Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP 986
Query: 588 HQTPAPLPNPGLY------------PPPVSMSP-----G-QPPPQQLLAPTYFSAPGVMN 629
Q P P P PPP P G QPPP Q P
Sbjct: 987 QQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSP 1046
Query: 630 FGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRT----P 685
+ S PY+ G L P P + + Q + +T+ +P QQ VQPK R P
Sbjct: 1047 RHHKSDPYSTGHLREAPSPLMIHSPQMSQ--FQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
Query: 686 QPVTI 690
QP+ +
Sbjct: 1105 QPLVV 1109
Score = 49.7 bits (117), Expect = 9e-06
Identities = 87/377 (23%), Positives = 127/377 (33%), Gaps = 59/377 (15%)
Query: 355 EQTSVRDPSPEADAPVLGSPEKEEAASEPPAAA---PDAAPPPPDRPIEKKSYSRARRTR 411
+ S D S E A L +++ A AA P P +K+ + +
Sbjct: 495 DSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRK 554
Query: 412 TKVGDAVKLAEEVPPPPE---------GLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGL 462
+V + K + PPP + + P P + PPT +E+ + +
Sbjct: 555 EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPT----YESEEEDKCKPM 610
Query: 463 EQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAK-- 520
+ + + N PG E G HI P + + +E+ + K
Sbjct: 611 SYEEKRQLSLDINKLPG--------EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPS 662
Query: 521 ------RYSSQRQRPVPEPPAPPVHI----SIMEGHYYDPLQFQGPIYTHG--DSPAPLP 568
RY + R +P A V + S M+G + + DS +
Sbjct: 663 TLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMA 722
Query: 569 PQGMLV-QPGMNLPHPGLHPHQT--PAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAP 625
P+ PG H HQ AP P P PPP P PPPQQ P P
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP 782
Query: 626 GVMNFGNPSYPY--APGALPPPPP------PHLYPNTQAPSQVYGGVTYYNPAQQQVQPK 677
PS P AP PPP P L P Q P V+ + ++ + P+
Sbjct: 783 -------PSMPQQAAPAMKSSPPPFIATQVPVLEP--QLPGSVFDPIGHFTQPILHL-PQ 832
Query: 678 PSPPRRTPQPVTIKPPP 694
P P PQP PP
Sbjct: 833 PELPPHLPQPPEHSTPP 849
Score = 33.1 bits (74), Expect = 0.90
Identities = 44/181 (24%), Positives = 63/181 (34%), Gaps = 33/181 (18%)
Query: 523 SSQRQRPVPEPPAPPVHISIMEGHYYDP-LQFQGPIYTHGDSPAPLPPQGMLVQPGMNLP 581
S+ Q P+P PPV + P L Q P+ T +PPQ + P P
Sbjct: 203 STPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT------VVPPQPLQTPP----P 252
Query: 582 HPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGA 641
P P PAP P P PP+ + QP + GV + + P
Sbjct: 253 VPP-QPQPPPAPAPQPVQSHPPIIAATPQPVK---------TKKGVKRKADTTTPTTIDP 302
Query: 642 LPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRG 701
+ PP P T Q++ +P P + P + + P PE S+
Sbjct: 303 IHEPPSLPPEPKTT------------KLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
Query: 702 S 702
S
Sbjct: 351 S 351
Score = 31.6 bits (70), Expect = 2.6
Identities = 24/83 (28%), Positives = 27/83 (32%), Gaps = 8/83 (9%)
Query: 619 PTYFSAPGVMNFGNPSYPYAPGALPPP--PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQP 676
P + P P P PPP PH +P V V P Q P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 677 KPSPPRR------TPQPVTIKPP 693
P PP+ PQPV PP
Sbjct: 251 PPVPPQPQPPPAPAPQPVQSHPP 273
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 66.6 bits (161), Expect = 7e-11
Identities = 92/362 (25%), Positives = 134/362 (37%), Gaps = 54/362 (14%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLA 421
P PE ++P+ SP EE+ + PP A +PPP + P + + +A+ L+
Sbjct: 442 PPPE-ESPL--SPPPEESPTSPPPEASRLSPPPEELP------------ASPLPEALHLS 486
Query: 422 ---EEVP--PPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTS-GLEQDVAQLNIAEQN 475
EE P PPPE P P PE++P P + P +S S LE ++ A
Sbjct: 487 RPLEESPLSPPPEE-SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 476 WSPGQPSFLQ--PRELRGMPNHIHMGAGPPPQFNRM------EEMGVQGGRAKRYSSQRQ 527
P + S L P EL P PPP+ + M M ++ + +
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Query: 528 RPVPEPP-----APPVHISIMEGHYYDPLQFQGPIYTHGDSP------APLPPQGMLVQP 576
P+ PP +PP S + D P + P +PLP L P
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665
Query: 577 GMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYP 636
P +P P PP SP PPP+ A S P + +
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA----SPPPEDSLMSLPLE 721
Query: 637 YAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVT--IKPPP 694
+P LP P P L P ++ P P + + P+P P +PQ + P P
Sbjct: 722 ESP-LLPLPEEPQLCPRSEGPH------LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
Query: 695 PE 696
E
Sbjct: 775 EE 776
Score = 63.5 bits (153), Expect = 6e-10
Identities = 109/405 (26%), Positives = 142/405 (35%), Gaps = 91/405 (22%)
Query: 355 EQTSVRDPSPEADAPVLG---SPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTR 411
+QT V D + + D P L P+ S PPAAAP P P S S +
Sbjct: 2086 KQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGL-STSADGFLK 2144
Query: 412 TKVGDA----------VKLAEEVPPP-----PEGLIPA-------PPVPETTPTPPTKTG 449
G +KL +VP P GL PA P P T P P+ TG
Sbjct: 2145 PPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG 2204
Query: 450 TWEAPV---DSSTSGLEQDVAQLNIAEQNWSPGQPS----FLQPR----ELRGMPNHIHM 498
P SS G Q + + QPS FL+PR + +P +
Sbjct: 2205 APAQPPMLGASSRPGAGQP-GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 499 GAG--------PPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDP 550
G G PPP + + V K+ P PP S G +
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEV-----KKEELGASSPSYGPPNLGFVDSPSSGTHLGG 2318
Query: 551 LQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQ 610
L+ + P APL P+ V+P +PGL + P +
Sbjct: 2319 LELKTPDVFK----APLTPRASQVEP------------------QSPGL-----GLRPQE 2351
Query: 611 PPPQQLLAPTYFSAPGVMNFGNPSYPYAPGAL---PPPPPPH---LYPNTQAPSQVYGGV 664
PPP Q LAP+ S P + G+ + PYA L P PPPP P PS + V
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRV 2411
Query: 665 TYYNPAQQQVQPKPSPPRR------TPQPVTIKPPPPEVVSRGSS 703
+P Q P PR P PVT + P+ SR S
Sbjct: 2412 P-ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPS 2455
Score = 61.6 bits (148), Expect = 2e-09
Identities = 90/369 (24%), Positives = 131/369 (35%), Gaps = 36/369 (9%)
Query: 356 QTSVRDPSPEA--------DAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIE---KKSY 404
+ S P PEA ++P+ SP EE+ PP A +PPP D P+ ++S
Sbjct: 586 EESPMSPPPEASRLFPPFEESPL--SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESP 643
Query: 405 SRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQ 464
+++ ++ PPP E + PP T PP + P DS TS +
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE 703
Query: 465 DVAQLNIAEQNWS----PGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAK 520
D E + P P E + P P P+ + + +
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 521 RYSSQRQRPVPEPPA-----PPVHISIM-EGHYYDPLQFQGPIYTHGDSP--APLPPQGM 572
+ P PE P H+S EG + P + + + P +P+P +
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 573 L-VQP-----GMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPG 626
L QP P L P + L +P L PP+S P +PP + P P
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHL-SPELEKPPLSPRPEKPPEEPGQCPAPEELPL 882
Query: 627 VMNFGNPSYPYAPG--ALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRT 684
G PS G AL P P L P + G +P Q + P P PP +
Sbjct: 883 FPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP--QLMPPDPLPPPLS 940
Query: 685 PQPVTIKPP 693
P PP
Sbjct: 941 PIITAAAPP 949
Score = 55.5 bits (132), Expect = 2e-07
Identities = 84/339 (24%), Positives = 117/339 (34%), Gaps = 88/339 (25%)
Query: 363 SPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDR---PIEKKSYSRARRTRTKVGDAVK 419
SP +A L P +E S PP +P + PP R P E+ S
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP------------ 611
Query: 420 LAEEVP--PPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWS 477
EE P PPPE +PP ++ +PP + P + S ++ L + +
Sbjct: 612 -PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR------LSPLPVVSRLSP 664
Query: 478 PGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPP 537
P + S L P PPP+ +R+ S P P +PP
Sbjct: 665 PPEESPLSPPPEES-------PTSPPPEASRLSP-------PPEDSPTSPPPEDSPASPP 710
Query: 538 VHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNP 597
S+M PL+ + P+ P P PQ G +L PH +P P P
Sbjct: 711 PEDSLMS----LPLE-ESPLL-----PLPEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEP 759
Query: 598 GLYP----PPVSMSPGQP-----PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPP 648
L P P +S P +P P + L+P A G P P P
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP---QAEG------------PHLSPQPEEL 804
Query: 649 HLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQP 687
HL P T+ P + P P P +PQP
Sbjct: 805 HLSPQTEEP---------------HLSPVPEEPCLSPQP 828
Score = 53.5 bits (127), Expect = 6e-07
Identities = 88/366 (24%), Positives = 124/366 (33%), Gaps = 34/366 (9%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVG 415
+ S P PE ++P SP E + PP +PPP D P +
Sbjct: 667 EESPLSPPPE-ESPT--SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
Query: 416 DAVKLAEE--VPPPPEG--LIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI 471
+ L EE + P EG L P P P +P P + +A + E+
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 472 AEQNWSP---GQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQR 528
E + SP G QP EL P P P+ + + S Q +
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEES----HLSPQSEE 839
Query: 529 PVPEPPAPPVHISI-MEGHYYDPLQFQGPIYTHGDSPAP-----LPPQG------MLVQP 576
P P H+S +E P + P G PAP PP G +L +P
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRP-EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP 898
Query: 577 GMNLP-HPGLHPHQTPAPLPNPGLYPP--PVSMSPGQPPPQQLLAPTYFSAPGVMNFGNP 633
++ P P L P PL +P P P M P PP T + P + G
Sbjct: 899 ALSEPGEPPLSPLPEELPL-SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 634 SYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNP---AQQQVQPKPSPPRRTPQPVTI 690
YP+ P P P + P +P + P P P P+ +
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017
Query: 691 KPPPPE 696
+P PP+
Sbjct: 1018 EPLPPQ 1023
Score = 43.9 bits (102), Expect = 5e-04
Identities = 56/220 (25%), Positives = 85/220 (38%), Gaps = 30/220 (13%)
Query: 502 PPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEP-PAPPVHISIMEGHYYDPLQFQGPIYTH 560
PPP+ + + + + + R P PE PA P+ ++ H PL+
Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLEESPLSPPP 498
Query: 561 GDSPAPLPPQGM---------LVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQP 611
+SP PP+ L P + P P L +P P +P PP SP P
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP--LSPPFEESPLSP 556
Query: 612 PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPP-----PPPHLY----PNTQAPSQVYG 662
PP++L PT S P + +P +P + PP PPP P ++P
Sbjct: 557 PPEEL--PT--SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
Query: 663 GVTYYNPAQQ--QVQPKPSPPRRTPQPVTIKPPPPEVVSR 700
+ +P + ++ P P +P P PP VSR
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Score = 38.1 bits (87), Expect = 0.028
Identities = 61/259 (23%), Positives = 79/259 (30%), Gaps = 39/259 (15%)
Query: 420 LAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPG 479
L + PPP + L P+PP P + T + P L Q P
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP-------------PLTPRPQPPPPE 2393
Query: 480 QPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSS-------QRQRPVPE 532
L PR L P + A P Q + + + A+ + Q P
Sbjct: 2394 SCCALPPRSLPSDP-FSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452
Query: 533 PPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPA 592
PP+ P Q + P P P PP+ + +L H L PA
Sbjct: 2453 PPSRP--------------QSRDPFAPLHKPPRPQPPE--VAFKAGSLAHTSLGAGGFPA 2496
Query: 593 PLPNPGLYPPPVSMSPGQPPPQQLLAPT--YFSAPGVMNFGNPSYPYAPGALPPPPPPHL 650
LP + GQPP T + P M F P P PP P P L
Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556
Query: 651 YPNTQAPSQVYGGVTYYNP 669
P S G T P
Sbjct: 2557 PPPHGINSHFGPGPTLGKP 2575
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/124 (30%), Positives = 47/124 (37%), Gaps = 19/124 (15%)
Query: 589 QTPAPLPNPGLYPPPVSMSPGQPP-----PQQLLAPTYFSAPGVMNFGNPSYPYAPGALP 643
QTP P PG P+ G P P P G G P P PGAL
Sbjct: 4239 QTP-PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALS 4297
Query: 644 ---------PPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK-PSPPRRTPQPVTIKPP 693
P PPP + PSQ+ + P + Q+ P P P+ PQ T++PP
Sbjct: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL-PTEAQLPPTHPGTPK--PQGPTLEPP 4354
Query: 694 PPEV 697
P V
Sbjct: 4355 PGRV 4358
Score = 37.4 bits (85), Expect = 0.048
Identities = 84/344 (24%), Positives = 111/344 (32%), Gaps = 66/344 (19%)
Query: 365 EADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEV 424
E +P LG +E PPA A AP PP P R
Sbjct: 2339 EPQSPGLGLRPQEP----PPAQA--LAPSPPSHP----DIFRPGSYTDPYAQPPLTPRPQ 2388
Query: 425 PPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFL 484
PPPPE PP + P+ P +P S+S L+ SP P F
Sbjct: 2389 PPPPESCCALPP--RSLPSDPFSRVP-ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445
Query: 485 QPRELRGMPNH---------IHMGAGPPPQFNRMEEMGVQGGRAKRYSSQR---QRPVPE 532
P P+ +H P P E+ + G S +P
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQPP-----EVAFKAGSLAHTSLGAGGFPAALPA 2500
Query: 533 PPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPA 592
PA +H + G P F T P P + Q + P L P
Sbjct: 2501 GPAGELHAKVPSGQ---PPNFVRSPGTGAFVGTPSPMRFTFPQA---VGEPSLKP----- 2549
Query: 593 PLPNPGLYPPPVSMSPGQPPPQQLLAP---TYFSAPGVMNF---GNPSYPYA-------- 638
P+P PGL PPP ++ P L P Y A G NF G+P P +
Sbjct: 2550 PVPQPGL-PPPHGINSHFGPGPTLGKPQSTNYTVATG--NFHPSGSPLGPSSGSTGESYG 2606
Query: 639 ------PGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQP 676
P LPPP P P + G+T +P +++ P
Sbjct: 2607 LSPLRPPSVLPPPAPDGSLPYLSHGASQRSGIT--SPVEKREDP 2648
Score = 36.2 bits (82), Expect = 0.11
Identities = 64/278 (23%), Positives = 89/278 (32%), Gaps = 46/278 (16%)
Query: 427 PPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQP 486
P + ++ P T P PP ++ G+ V QL Q P
Sbjct: 4155 PQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP----- 4209
Query: 487 RELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGH 546
+LR + P Q +++ + +Q + SQ R P P S ++G
Sbjct: 4210 -QLRHLS---------PQQQQQLQALLMQ---RQLQQSQAVRQTPPYQEPGTQTSPLQGL 4256
Query: 547 YYDPLQF-------QGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHP-HQTPAP-LPNP 597
Q GP+ G P P P + PG P L P H TP P P
Sbjct: 4257 LGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE 4316
Query: 598 GLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPG----------------A 641
P + Q P + L PT+ PG P+ PG
Sbjct: 4317 PKRPSQLPSPSSQLPTEAQLPPTH---PGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKG 4373
Query: 642 LPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPS 679
L P PP TQ P Q + + QV P+ S
Sbjct: 4374 LGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEAS 4411
Score = 33.9 bits (76), Expect = 0.53
Identities = 44/161 (27%), Positives = 57/161 (35%), Gaps = 25/161 (15%)
Query: 502 PPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIME------GHYYDPLQFQG 555
P P+ R G + R + PVP P P I + G P QG
Sbjct: 2841 PGPELGRQALGSPLAGISTRLPGPGE-PVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQG 2899
Query: 556 P-----IYTHGDSPAPLPPQGM--LVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSP 608
P Y + P L P+G+ L G+ P P PAP N L+P P + P
Sbjct: 2900 PPQRPRFYPVSEDPHRLAPEGLRGLAVSGL----PPQKPSAPPAPELNNSLHPTPHTKGP 2955
Query: 609 GQPPPQQLLAPTYFSAPGVMNFGNPSYPYA--PGALPPPPP 647
P +L+ P G P+ P A G LP P
Sbjct: 2956 TLPTGLELVN----RPPSSTELGRPN-PLALEAGKLPCEDP 2991
Score = 33.9 bits (76), Expect = 0.53
Identities = 38/139 (27%), Positives = 51/139 (36%), Gaps = 22/139 (15%)
Query: 556 PIYTHGDSPAPLPPQGML-VQPGMN-LPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPP 613
P G +PL QG+L QP + P P P Q P P PP + PG
Sbjct: 4242 PYQEPGTQTSPL--QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ-GPPRLPAPPGALST 4298
Query: 614 QQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQ 673
+L P + + P +P P P LP P ++Q P++ P
Sbjct: 4299 GPVLGPVHPTPPP----SSPQEPKRPSQLPSP-------SSQLPTEA------QLPPTHP 4341
Query: 674 VQPKPSPPRRTPQPVTIKP 692
PKP P P P + P
Sbjct: 4342 GTPKPQGPTLEPPPGRVSP 4360
Score = 32.3 bits (72), Expect = 1.5
Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 18/97 (18%)
Query: 562 DSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPN-PGLYPPPVSMSPGQPPPQQLLAPT 620
+SPAP PP Q L Q AP P P P P++ SP PP + L+
Sbjct: 4882 ESPAPEPP----TQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVE-- 4935
Query: 621 YFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAP 657
P+ P A +P P P P + P
Sbjct: 4936 -----------LPTEPLAEPPVPSPLPLASSPESARP 4961
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 66.2 bits (160), Expect = 1e-10
Identities = 100/361 (27%), Positives = 132/361 (36%), Gaps = 61/361 (16%)
Query: 383 PPAAAPDAAPPPPDR-PIEKKSYSRARRTRTKV------GDAVKLAEEVPP--PP----- 428
P AP APPPP + SY+ R+ + A PP PP
Sbjct: 205 PRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCS 264
Query: 429 EGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRE 488
+ L P PP+P + P + PV S+T L + L A PG P FL
Sbjct: 265 DALTP-PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSL 323
Query: 489 LRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYY 548
L H PPP + Q A SS R P PP ++EG
Sbjct: 324 LSAAAKAQHPPL-PPPSTLQGRRPRAQAPSASHSSSLRPSQ-RRPRRPPTVFRLLEGR-- 379
Query: 549 DPLQFQGPIYTHGDSPAPLPPQGMLVQPG----------MNLPHPG-LHPHQTPAPLPNP 597
P Q P + +PAP+P L +P + LP PG H + L +
Sbjct: 380 GP---QTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
Query: 598 GLYPPPVSMSPGQPP-PQQLLAPTYFSAPGVMNFGNPSYPYAPGALPP---PPPPHLYPN 653
PPP ++S G PP P+ + P S PG + S P AP PP P P
Sbjct: 437 AHLPPPPTLSSGSPPQPRHPIQP---SLPGTTSGSLSSVPGAPA--PPAASKAPVVPSPV 491
Query: 654 TQAPSQVYG-GVTYYNP----AQQQVQPKPSPPR--------------RTPQPVTIKPPP 694
Q+PS+ G G P A + P PSP + P P+++ PP
Sbjct: 492 LQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPP 551
Query: 695 P 695
P
Sbjct: 552 P 552
Score = 52.8 bits (125), Expect = 1e-06
Identities = 77/317 (24%), Positives = 110/317 (34%), Gaps = 66/317 (20%)
Query: 369 PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPP 428
P +P ++S P+ PP R +E + RR+R + V +P P
Sbjct: 346 PRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPS 405
Query: 429 EGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRE 488
+ ++P+ PTP G N+ G + L P
Sbjct: 406 QPILPSVLSLLGLPTP----------------GPSHSDGSFNLL------GSDAHLPPPP 443
Query: 489 LRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP--APPVHISIME-- 544
+ +G PPQ + + G + SS P P AP V +++
Sbjct: 444 T--------LSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
Query: 545 ----GHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQ----PGM--NLPHPGLHPHQTPAPL 594
G P P+ P P P QG+ + PGM LP P P+PL
Sbjct: 496 SEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL 555
Query: 595 PNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGA-----------LP 643
N L+ ++ GQPPP+ LL P G P P APG LP
Sbjct: 556 LNHSLFGV-LTGGGGQPPPEPLLPPP----------GGPGPPLAPGEPEGPSLLVASLLP 604
Query: 644 PPPPPHLYPNTQAPSQV 660
PPP L P + PS +
Sbjct: 605 PPPSDLLPPPSAPPSNL 621
Score = 39.3 bits (90), Expect = 0.013
Identities = 59/231 (25%), Positives = 71/231 (30%), Gaps = 38/231 (16%)
Query: 475 NWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP 534
N PG P + P G PP+ G G + R+ + P P PP
Sbjct: 158 NGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSG--GSSSPRFLPRGNAPSPAPP 215
Query: 535 APPVHISIMEGHY---------YDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGL 585
PP IS+ Y P P H S P P L L P L
Sbjct: 216 PPPA-ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPP--LFHCSDALTPPPL 272
Query: 586 HPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSY-------PYA 638
P P P PP S + P L+ AP V G P + A
Sbjct: 273 PPSNNLPAHPGPASQPPVSSATMHLP----LVLGPLGGAPTVEGPGAPPFLASSLLSAAA 328
Query: 639 PGALPPPPPPHLY----PNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTP 685
PP PPP P QAPS + ++P PRR P
Sbjct: 329 KAQHPPLPPPSTLQGRRPRAQAPSASH---------SSSLRPSQRRPRRPP 370
Score = 32.3 bits (72), Expect = 1.5
Identities = 77/311 (24%), Positives = 105/311 (33%), Gaps = 51/311 (16%)
Query: 378 EAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKV--GDAVKLAEEVPPPPEGLIPAP 435
+A PP +PP P PI+ + + V A A + P P ++ +P
Sbjct: 436 DAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
Query: 436 P------VPETTPTPPTKTGTWEAPVDSSTSGLEQDVA----QLNIAEQNWSPGQP--SF 483
P PP G P S GL A L S GQP S
Sbjct: 496 SEGLGMGAGPACPLPPLAGGE-AFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSP 554
Query: 484 LQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQG---------GRAKRYSSQRQRP----V 530
L L G+ + G G PP + G G G + +S P +
Sbjct: 555 LLNHSLFGV---LTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLL 611
Query: 531 PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDS-------PAPLPPQGM-----LVQPGM 578
P P APP ++ + PL GP G+ P+ P G+ L+ P +
Sbjct: 612 PPPSAPPSNLLAS----FLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL 667
Query: 579 NLPHP--GLHPHQTPAPLPNPGLYPP-PVSMSPGQPPPQQLLAPTYFSAPGVMNFGN-PS 634
+ P L+ A L P PP P +S QP P T + PG + G PS
Sbjct: 668 SAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPS 727
Query: 635 YPYAPGALPPP 645
P L P
Sbjct: 728 NSGRPPQLLSP 738
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 65.5 bits (158), Expect = 2e-10
Identities = 89/356 (25%), Positives = 115/356 (32%), Gaps = 41/356 (11%)
Query: 358 SVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAP-PPPDRPIEKKSYSRARRT--RTKV 414
+V PSP+ P+ AS PPAA P + P P+ K + + T K
Sbjct: 1013 AVTPPSPKGSPAATPFPK---GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 415 GDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQ 474
G A + P PP PP P+ P P+ G P + S L
Sbjct: 1070 GPATPSLKGAPTPPAA---TPPSPKGGPATPSPKGAPMPPAATPPS----PKGGLATPPH 1122
Query: 475 NWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPP 534
+P P+ P G+ GA P G G P PP
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG--GLATPPPKGAPTTPAATPP 1180
Query: 535 APPVHISIMEGHYYDPLQFQGPIYTHGDSPAPL------PPQGMLVQPGMNLPHP--GLH 586
+P +G P P P+P P+G P P P GL
Sbjct: 1181 SP-------KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVM-NFGNPSYPYAPG-ALPP 644
P PP P PPP+ P + P + P + AP A+
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 645 PPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPS----PPRRTPQPVTIKPPPPE 696
PP P P T P G T PA PK S PP+ P P + PP P+
Sbjct: 1294 PPSPKGGPATSPPK---GAPT--PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Score = 63.5 bits (153), Expect = 6e-10
Identities = 95/387 (24%), Positives = 124/387 (32%), Gaps = 76/387 (19%)
Query: 344 KHEISYRSRRLEQTSVRDPSPE----ADAPVLGSPEKEEAASEPPAAAPD---------- 389
++ +S++ + + P+P A P +P + + PP P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 390 ---AAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPT 446
A P P P + S ++ R P P+G IPA P P+ PTPP
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARAT------------PAPKG-IPASPSPKGAPTPPA 944
Query: 447 KTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQF 506
T ++ S W+P P+ P G GA PP
Sbjct: 945 ATPPSPKGGPATPS-------------PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991
Query: 507 NRMEEMGVQGGRAKRYSSQRQRPVPEPPAP---PVHISIMEGHYYDPLQFQGPIYTHGDS 563
G G P PP+P P +G P P G S
Sbjct: 992 TPPSPKG--GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA--ATPPSPKG-S 1046
Query: 564 PAPLP-PQGMLVQPGMNLPHPGLHPHQTP----APLPNPGLYPPPVSMSPGQPPPQQLLA 618
PA P P+G P LP P P TP AP P P PP P P P+
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGP-ATPSLKGAPTP-PAATPPSPKGGPATPSPKGAPM 1104
Query: 619 PTYFSAP----GVMNFGNPSYPYAPGALPP-------PPPPHLYPNTQA--PSQVYGGVT 665
P + P G+ + P P A PP PPP P T A P GG+
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 666 YYNPAQQQVQPKPSPPR-----RTPQP 687
P P +PP TP P
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSP 1191
Score = 55.8 bits (133), Expect = 1e-07
Identities = 90/384 (23%), Positives = 127/384 (33%), Gaps = 60/384 (15%)
Query: 359 VRDPSPE---ADAPVLGSPEKEEAASEPPAAAPDAAPP------PPDRPIEKKSYSRARR 409
V PSP+ A +P G+P A P +P PP P P K
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 410 TR--TKVGDAVKLAEEVPPPPE-------GLIPAPPVPETTPTPPTKTGTWEAPVD---S 457
T +K G ++E P PP G PP P+ P P+ G +P S
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
Query: 458 STSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEM--GVQ 515
V + A + P + P L+ P GP ++ + V
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 516 GGRAKRYSSQRQ-------RPVPEPPAP-------------PVHISIMEGHYYDPLQFQG 555
K + +Q + P PAP P + DP+
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 556 PIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQ 615
+ + +PA L P+ L+ P M +P P +TPA +P P P S PP
Sbjct: 1532 TLLSK-KTPATLAPKEALIPPAMTVP----SPKKTPA-IPTPKEAPATPSSKEASSPP-A 1584
Query: 616 LLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQ 675
+ TY AP P +P P PP + P PS G PA +
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP----PSPEKG------PATPAPK 1634
Query: 676 PKPSPPRRTPQPVTIKPPPPEVVS 699
P+ P TP + P P V+
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVT 1658
Score = 52.0 bits (123), Expect = 2e-06
Identities = 95/356 (26%), Positives = 122/356 (34%), Gaps = 93/356 (26%)
Query: 364 PEADAPVLGSP---EKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P P G+P +K + S A AP A P + P E S A T + G L
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAP-VASSPKECPTED---SGASATASSKGTLTYL 790
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
A+ P P G+ +P T PPTK G+ A D+ L V SP +
Sbjct: 791 ADS--PSPLGVSVSPQ----TKRPPTKKGS--AGPDTPIGNLSSPV----------SPVE 832
Query: 481 PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHI 540
SFL L QG + ++ P P P P
Sbjct: 833 ASFLPENSL-----------------------SFQGSKDSPATTHSPTP-PSPKGAPTPS 868
Query: 541 SIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLY 600
++ PL +G LPP+ +NLP P P TPAP P L
Sbjct: 869 AVT------PLSPKG---------VTLPPKETPTPSVVNLPFPKEGP-ATPAPKQAPALS 912
Query: 601 ------------PPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPP--- 645
P P + P P P+ APT +A G P+ P A PP
Sbjct: 913 MTSSSPKKARATPAPKGI-PASPSPKG--APTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 646 -PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSP----PRRTPQPVTIKPPPPE 696
P P P T +P G T PA PK P P+ P P + PP P+
Sbjct: 970 PPSPKGGPATPSPK---GAPT--PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Score = 49.7 bits (117), Expect = 9e-06
Identities = 95/358 (26%), Positives = 133/358 (37%), Gaps = 61/358 (17%)
Query: 362 PSPEADAPVLGSPEKEEA------ASEPPAAAPDA---APPPPDRPIEKKSYSRARRTRT 412
PSP+ P + +P++ A AS PPA P AP P + I S + +
Sbjct: 1556 PSPKK-TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK--- 1611
Query: 413 KVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIA 472
+A PP PE PA P P+ TPT P T + + DS TS ++
Sbjct: 1612 ---EAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVTPS--SLKDSPTSPASV-TCKMGAT 1664
Query: 473 EQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPV-P 531
S G P+ P L+ + P P+ + + G + SS P+ P
Sbjct: 1665 VPQASKGLPAKKGPTALK------EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
Query: 532 EPPA---PPVHISIMEGHYYDPLQ------FQGPIYTHGDSPAPLPPQGMLVQP------ 576
+P A +S + P+Q +G +H PP+ P
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778
Query: 577 GMNLPHP-GLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSY 635
LP P P+P + L P PV P PP QQ L S+PG++ +PS
Sbjct: 1779 EKVLPKPESASVSAAPSPPVSLPLAPSPV---PTLPPKQQFLP----SSPGLV-LESPSK 1830
Query: 636 PYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK----PSPPRRTPQPVT 689
P AP P L P P + GGV + + PK P P QPVT
Sbjct: 1831 PLAPADEDELLP--LIP----PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882
Score = 48.1 bits (113), Expect = 3e-05
Identities = 88/362 (24%), Positives = 118/362 (32%), Gaps = 66/362 (18%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPD-----AAPPPPDRPIEKKSYSRARRTRTKVGD 416
PSP+ L +P + A + P A P A PPP P + A K G
Sbjct: 1111 PSPKGG---LATPPHKGAPTTPAATPPSPKGGLATPPPKGAP----TTPAATPPSPKGGL 1163
Query: 417 AVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNW 476
A + P P P+P TP+P T A S GL
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-------SPKG 1216
Query: 477 SPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP 536
+P P+ P G+ GA P +GG A + P P P
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---KGGPAT--PPPKGAPTPPAATP 1271
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPA----PLPPQGMLVQPGMNLPHPGLHPHQTP- 591
P S+ G P + +PA P P G P P P P TP
Sbjct: 1272 P---SLKGG-------LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP---PAATPP 1318
Query: 592 APLPNPGLYPP-----PVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPP 646
+P +PG PP P +++P P L T S+ G P P + P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG--------GPTTPSSKEGPT 1370
Query: 647 PPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTI-----KPPPPEVVSRG 701
PP P+ + GG P+ ++ PSP P I K P V G
Sbjct: 1371 PPAATPSHK------GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 702 SS 703
++
Sbjct: 1425 AA 1426
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 64.7 bits (156), Expect = 3e-10
Identities = 86/362 (23%), Positives = 125/362 (34%), Gaps = 51/362 (14%)
Query: 369 PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPP 428
P + P K+ A + P ++ A P P ++ ++ T +LA +P P
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 429 EGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRE 488
APP +T P+PP P +T+ L Q + P P P +
Sbjct: 343 PSP-SAPPSLQTLPSPPA------TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395
Query: 489 LRGMPNHIHMGAGP-PPQFNRMEEMGVQGGRAKRYSSQR--QRPVPEPPAPPVHISIMEG 545
+ A P PP + + +A + Q P PP+PPV +
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-----QA 450
Query: 546 HYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVS 605
+ P P+ P+ PP L P + +P P +P +P PPP +
Sbjct: 451 PFSPPAS--PPVSPSATPPSQAPPS--LAAPPLQVP-----PSPPASPPMSPSATPPPQA 501
Query: 606 MSPGQPPPQQLL-----APTYFSAPGVMNFGNP--------------SYPYAPGALPPP- 645
P PP QL AP + P + +P S P +P A PPP
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561
Query: 646 -PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQP---VTIKPPPPEVVSRG 701
PP P Q P T P + P P P P + + P PP SR
Sbjct: 562 APPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 702 SS 703
S
Sbjct: 619 PS 620
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/314 (25%), Positives = 105/314 (33%), Gaps = 62/314 (19%)
Query: 357 TSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPP---PDRPIEKKSYSRARRTRTK 413
TS+ P+ +A L SP A+ PP A P A PP P P S +
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426
Query: 414 VGDAVK---LAEEVPPPPEGLIPAP-PVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL 469
+A+ L PPP + AP P + P P+ T +AP + L+
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ------ 480
Query: 470 NIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRP 529
P P P + A PPPQ + Q
Sbjct: 481 -------VPPSPPASPP---------MSPSATPPPQ-----------APPPLAAPPLQLA 513
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
P P APP + P+ PA P Q P +LP + P
Sbjct: 514 KPPPQAPPALAT-------------PPLQALPSPPASFPGQAPF-SPSASLP---MSPLA 556
Query: 590 TPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPH 649
TP P P L P + + P P L AP PG + S P AL P PPP
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRLTLALAPGPPP- 613
Query: 650 LYPNTQAPSQVYGG 663
P +++PS G
Sbjct: 614 --PPSRSPSSTLSG 625
Score = 53.5 bits (127), Expect = 6e-07
Identities = 103/463 (22%), Positives = 145/463 (31%), Gaps = 116/463 (25%)
Query: 337 GRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPP-- 394
G +G + ++ R+ + ++ + +P A AS PPA+ PP
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 395 ---------PDR--------PIEKK--------SYSRARRTRTKVGDAVKL-AEEVPPPP 428
P R P+ +K + +R + T A+ A P
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
Query: 429 EGLIPAP-----------------PVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI 471
P+P P P P PPT E P S +S E + +
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT-----EGPRKSVSSASEHSTTEPSP 222
Query: 472 AEQNWSPGQPSFLQPRELRGM-----PNHIHMGAGP--------PPQFNRMEEMGVQGGR 518
A + P LQ R + P +GP P ++ + G+Q R
Sbjct: 223 AARR-RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 519 AKRYSSQRQRPVP-------------------EPPAPPV-----HISIMEGHYYDPLQFQ 554
+ + R+ P + APP H S + PL
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341
Query: 555 GP-------IYTHGDSPAPLPPQG--MLVQPGMN-----LPHPGLHPHQTPAPLPNPGLY 600
P + T PA P Q L P + LP P L P TP P P L
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 601 PPPVSMSPGQP--PPQQLLAPTYFSAPGVM-------NFGNPSYPYAPGALPPPPPPHLY 651
PP+ P P PP LA AP + F P P PP P +
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 652 PNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
P+ PSQ + A +Q PSPP P + PPP
Sbjct: 462 PSATPPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPP 499
Score = 43.9 bits (102), Expect = 5e-04
Identities = 69/296 (23%), Positives = 98/296 (33%), Gaps = 73/296 (24%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLA 421
P P+A P+ P + ++PP AP A PP + + S + ++ ++
Sbjct: 497 PPPQAPPPLAAPPLQ---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553
Query: 422 EEVPPPPEGL-IPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVA--QLNIAEQNWSP 478
PPP+ + A P+ + P+PP T +AP T G + V+ +L +A P
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 479 GQPSFLQPRELRG--MPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP 536
PS L G + H P + R + G +GG A P P+
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDSGPEGGAAAS-------PPPDAELA 664
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPN 596
H + S P PP PG LP P P
Sbjct: 665 ACHPAAW-------------------SRGPAPPLAFRGAPGAPLPWP---------PATG 696
Query: 597 PGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNF----GNPSYPYAPGALPPPPPP 648
PG SA G+ G S APGAL P P P
Sbjct: 697 PG------------------------SADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 32.0 bits (71), Expect = 2.0
Identities = 34/131 (25%), Positives = 44/131 (33%), Gaps = 1/131 (0%)
Query: 339 SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRP 398
SG + S + E+ D PE A P+ E AA P A + APP R
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 683
Query: 399 IEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSS 458
T D + E PE PAP + P+P T G A +
Sbjct: 684 APGAPLPWPPATGPGSADGLCTIYET-EGPESATPAPGALDPGPSPGTSGGKAAAGAGAG 742
Query: 459 TSGLEQDVAQL 469
S A+L
Sbjct: 743 ASSRSPKQARL 753
Score = 30.0 bits (66), Expect = 7.6
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 19/112 (16%)
Query: 12 DTEDEESG--ASGS-DSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVES-- 66
+TE ES A G+ D G SP GG + AG G S P Q R G L L +++
Sbjct: 708 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ--ARLGELPLGALQASV 765
Query: 67 -----------GGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSE 107
A+ A G EG V +A S+ E G ++E
Sbjct: 766 VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAAL-SDAELGRWAE 816
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 64.3 bits (155), Expect = 4e-10
Identities = 101/378 (26%), Positives = 130/378 (34%), Gaps = 79/378 (20%)
Query: 372 GSPEKEEAASE---PPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAV---KLAEEVP 425
G PE A++ PP P E R + G +V KL P
Sbjct: 440 GQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP 499
Query: 426 PP-------------PEGLIPAPPVPETT-----PTPPTKTGTWEA--------PVDSST 459
PP P+G + PP PE P PPT G+ A P +S
Sbjct: 500 PPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWV 559
Query: 460 SGLEQDVAQL--NIAEQNWSP--------GQPSFLQPRELRGMPNHIHMGAGPPPQFNRM 509
GL ++ E+ SP G P+ L P+ L G P G PP+ R+
Sbjct: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT-LPPKGLAGPP--ASPGKAQPPKPERV 616
Query: 510 EEMGVQGGRAKR----YSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPA 565
+ G S P P + P ++ PL + I H PA
Sbjct: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILT--------PLGDRFVIPPHPKVPA 668
Query: 566 PLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSM---SPGQPP-PQQLLAPTY 621
P P P P+ L P + P PVS SP PP PQ L P
Sbjct: 669 PFSPP----------PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718
Query: 622 FSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNT--QAPSQVYGGVTYYNPAQQQVQPKPS 679
S P + +P P P + PPPPP P +APS T P Q P P
Sbjct: 719 ES-PVISKDQSPP-PSPPPSYHPPPPPTKKPEVVVEAPS---ASETAEEPLQDPNWPPPP 773
Query: 680 PPRRTPQPVTIKP-PPPE 696
PP Q +++ PPPE
Sbjct: 774 PPAPEEQDLSMADFPPPE 791
Score = 49.7 bits (117), Expect = 9e-06
Identities = 97/407 (23%), Positives = 143/407 (35%), Gaps = 87/407 (21%)
Query: 314 SRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEIS----YRSRRLEQTSVRDPSPEADAP 369
S SGG + + + GQ GRS K + R+ L Q + P D P
Sbjct: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVP----DGP 518
Query: 370 VLGSPEKEEAASEPPAAAPD---------AAPPPPDRP---IEKKSYSRARRT-----RT 412
LG P K E +P P AAP PP+ + S +RR RT
Sbjct: 519 -LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERT 577
Query: 413 KVGDAVKLAEEVPP--PPEGLIPAPPVP-ETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL 469
+ ++ P PP+GL P P + P P + + +P S +S L +
Sbjct: 578 LSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS 637
Query: 470 NIAEQNWSPGQPSFLQPRELRGM-PNHIHMGA--GPPPQFNRMEEMGVQGGRAKRYSSQR 526
+ + G P L P R + P H + A PPP R
Sbjct: 638 SDPAPSDRSG-PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS----------------- 679
Query: 527 QRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLH 586
P P AP + P GP+ T SP P + P P +
Sbjct: 680 ----PNPAAPALAA---------PAVVPGPVSTTDASPQSPPTPQTTLTPLQE--SPVIS 724
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPP 646
Q+P P P P +PPP P P+ ++ S +P++P PPPP
Sbjct: 725 KDQSPPPSPPPSYHPPP----PPTKKPEVVVEAPSASETAEEPLQDPNWP------PPPP 774
Query: 647 PPHLYPNTQAPSQVYGGVTYYNPAQQQ----VQPKPSPPRRTPQPVT 689
P AP + + + P ++ P+P+ P +P+ V+
Sbjct: 775 P--------APEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVS 813
Score = 40.8 bits (94), Expect = 0.004
Identities = 89/393 (22%), Positives = 118/393 (30%), Gaps = 118/393 (30%)
Query: 362 PSPEAD-APVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P+P+ P+ SP + S PP+ P PPPP P +K + ++ +
Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP--PTKKPEVVVEAPSASETAEEPLQ 765
Query: 421 AEEVPPPPEGLIPAP----------PVPE------TTPTPPTKTGTWEAPVDSSTSGLEQ 464
PPPP PAP P PE +P P +G+ E + SS +
Sbjct: 766 DPNWPPPPP---PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPE--LVSSPAASSS 820
Query: 465 DVAQLNIAEQNWSPGQPSFLQPRELRGMPNHI-----------HMGAGPPP--------- 504
L I P+ P P H+ G GPP
Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880
Query: 505 ----QFNRMEEMGVQGGR-------------AKRYSSQRQRPVPEPPAPPVH-------I 540
Q R+ +G GG +R S R PVP P+ +H
Sbjct: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVP-APSSGLHAAVRLKAC 939
Query: 541 SIMEGHYYDPLQFQGPIYTHGDSP-APLPPQGMLVQPG---MNLPHP------------- 583
S+ Q GP P +P + G + L P
Sbjct: 940 SLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNL 999
Query: 584 --------GLHPHQTPAPLPNPGLYPPPVSMSP--GQPPPQQLLAPTYFSAPGVMNFGNP 633
P Q P P PPPV+ P G PPP +P
Sbjct: 1000 VAELRSISEQRPPQAPKKSPKA---PPPVARKPSVGVPPP-----------------ASP 1039
Query: 634 SYPYAPGALPPPPP--PHLYPNTQAPSQVYGGV 664
SYP A PP PH T+ GGV
Sbjct: 1040 SYPRAEPLTAPPTNGLPHTQDRTKRELAENGGV 1072
Score = 38.5 bits (88), Expect = 0.021
Identities = 54/211 (25%), Positives = 66/211 (31%), Gaps = 69/211 (32%)
Query: 561 GDSPAPLPPQGMLVQPGMN---LPHPGLHPHQTPAP------------LPNPGLYPPPVS 605
G +P P P V PG++ P P +T +P LP GL PP S
Sbjct: 546 GAAPCPPNPANSWV-PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS 604
Query: 606 MSPGQPPPQQLL------------------------APTYFSAPGVMN-----FGNPSYP 636
QPP + + AP+ S P ++ F P +P
Sbjct: 605 PGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP 664
Query: 637 YAPGALPPPPPPHLYPNTQAPS----QVYGGVTYYNPAQQQVQPKP-------------- 678
P PPP PN AP+ V G A Q P P
Sbjct: 665 KVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724
Query: 679 ---SPPRRTPQPVTIKPPP---PEVVSRGSS 703
SPP P PPP PEVV S
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755
Score = 30.4 bits (67), Expect = 5.9
Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 30/144 (20%)
Query: 377 EEAASEPPAAAPDAAPPPPDRPIEKKSY------------------SRARRTRTKVGDAV 418
E +S P P+A P PP P S+ ++A R V +
Sbjct: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELR 1004
Query: 419 KLAEEVPP-PPEGLIPAPPVPETTPT---PPTKTGTW---EAPVDSSTSGL--EQDVAQL 469
++E+ PP P+ APP P+ PP + ++ E T+GL QD +
Sbjct: 1005 SISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKR 1064
Query: 470 NIAEQNWSPGQPSFLQPRELRGMP 493
+AE G + P E G+P
Sbjct: 1065 ELAENG---GVLQLVGPEEKMGLP 1085
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 63.9 bits (154), Expect = 5e-10
Identities = 98/409 (23%), Positives = 141/409 (34%), Gaps = 105/409 (25%)
Query: 369 PVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPP 428
P + P K+ A + P ++ A P P S ++AR A L +PP P
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSP-------SGTKARPVPPPDNAATPLPATLPPSP 335
Query: 429 EGLIP---------APPVPETTPTPPTKTGTWEAPVDSSTSGLE-----QDVAQLNIAEQ 474
P APP +T P+PP T +AP +T ++ Q + + +
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPA-TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 475 NWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQR-------- 526
SP + P L + +G+ + M + +A S R
Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 527 ---QRPVPEPPAPPVHISIMEGHY-------YDPLQFQGPIYTHGDSPAPL--------- 567
Q P+ P +PP+ S+ PLQ + +H APL
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ-APLSSLIMPPLE 513
Query: 568 ------------PPQGMLVQPGMNLPHPGLHPHQT-------------PAPLPNPGLYPP 602
PP + P NLP P QT P P P P PP
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 603 -PVSMSPGQ-------PPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPP--PPPHLYP 652
P++ P + PPPQ AP ++P + G PS P +P A PPP PP P
Sbjct: 574 SPLTTPPPETPSSIATPPPQ---APPALASPPLQ--GLPSPPLSPLATPPPQAPPXLALP 628
Query: 653 NTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTI-------KPPP 694
QAP PA + P +P + P + + PPP
Sbjct: 629 PLQAPPS--------PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Score = 63.5 bits (153), Expect = 6e-10
Identities = 98/369 (26%), Positives = 133/369 (36%), Gaps = 45/369 (12%)
Query: 357 TSVRDPSPEADAPVLGSP--EKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKV 414
+S+ SP+A L P E + + + P P A+ P P+E +T
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP--PLENLPSLAPPPLQTAS 550
Query: 415 GDAVKLAEEVPPPPEGL-IPAPPVPETTPTPPTKTGTWEAPVDSS---TSGLEQDVAQLN 470
E PP P + APP P TTP P T + P + S Q +
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 471 IAEQNWSPGQ-PSFLQPRELRGMPNH-----IHMGAGPPPQF-NRMEEMGVQGGRAKRYS 523
++ P Q P L L+ P+ + A P PQ N + +Q + S
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 524 SQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHP 583
Q P P +PPV S P P+ PA PP P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-PPMSPSATP------- 722
Query: 584 GLHPHQTPAPLPNPGLYPPP-----VSMSPGQPPPQQLLAPTYFSAPGVMNFGNP--SYP 636
P Q P PL P L PP MSP PP ++ P +AP + +P S P
Sbjct: 723 ---PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--PPLLAAPPLQVPPSPPASLP 777
Query: 637 YAPGALPPP--PPPHLYPNTQA----PSQVYGGVTYYNPAQQQVQPKPSPPRRTP----Q 686
+P A PPP PP P QA P+ G + A + P +PP + P
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837
Query: 687 PVTIKPPPP 695
P+ PP P
Sbjct: 838 PLLQVPPSP 846
Score = 56.6 bits (135), Expect = 8e-08
Identities = 84/326 (25%), Positives = 113/326 (34%), Gaps = 35/326 (10%)
Query: 357 TSVRDPSPEADAPV-------LGSPEKEEAASEPPAAAPDAAPPP---PDRPIEKKSYSR 406
+S+ P P+A + L SP A+ PP A P A PP P P S
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 407 ARRTRTKVGDAVK---LAEEVPPPPEGLIPAP-PVPETTPTPPTKTGTWEAPVDSSTSGL 462
+ +A+ L PPP + AP P + P P+ T +AP + L
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
Query: 463 EQDVAQLNIAEQNWSPGQ-PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKR 521
+ V A SP P P L P + PP M R
Sbjct: 705 Q--VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS---PPASPPMSPSATPPPRVPP 759
Query: 522 YSSQRQRPVPEPPAPPVHISIME----GHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPG 577
+ P+ PP+PP + + P P+ PA P Q P
Sbjct: 760 LLAAP--PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF-SPS 816
Query: 578 MNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPY 637
+LP + P TP P P L P + + P P L AP PG + S P
Sbjct: 817 ASLP---MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPR 871
Query: 638 APGALPPPPPPHLYPNTQAPSQVYGG 663
AL P PPP P +++PS G
Sbjct: 872 LTLALAPGPPP---PPSRSPSSTLSG 894
Score = 44.3 bits (103), Expect = 4e-04
Identities = 83/325 (25%), Positives = 100/325 (30%), Gaps = 73/325 (22%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPDAAPP-PPDRPIEKKSYSRARRTRTKVGDAVKL 420
PSP A P+ S A P AA P PP PP P S + R + A L
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA-APPL 766
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
+VPP P +P P+ + P P T L A PGQ
Sbjct: 767 --QVPPSPPASLPMSPLAKPPPQAPPALAT------PPLQALPSPPASF--------PGQ 810
Query: 481 PSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHI 540
F L P A PPPQ + + +S + PP P
Sbjct: 811 APFSPSASLPMSPL-----ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865
Query: 541 SIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPA---PLPNP 597
S+ GP T +P P PP P L P L H + A P
Sbjct: 866 SV-----------SGPRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 598 GLYPPPVSMSPGQPPPQQLLA---PTYFS---APGVMNFGNPSYPY-------------- 637
G P + PPP LA P +S AP + G P P
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 638 --------------APGALPPPPPP 648
APGAL P P P
Sbjct: 973 CTIYETEGPESATPAPGALDPGPSP 997
Score = 43.5 bits (101), Expect = 7e-04
Identities = 102/425 (24%), Positives = 135/425 (31%), Gaps = 79/425 (18%)
Query: 281 SHRHQGLGG-TLP---PRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHG 336
+ R G+GG T+P PR R+A + R A R + G + A G
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
Query: 337 GRSGETVKHEISYRSRRL--EQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPP 394
SG T + + R+ E+T R + EA K A S A D + P
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAP--------KRSALSA--GARRDTSGPT 168
Query: 395 PDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAP 454
P P S + ARR+R G V L P P P PPT E P
Sbjct: 169 PGTP----SPAMARRSRA-AGTEVGLPR-------------PAPSARPRPPT-----EGP 205
Query: 455 VDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGV 514
S +S E + + A + +PS G G +R
Sbjct: 206 RKSVSSASEHSTTEPSPAARR----RPS---------------AGGGLQRPASRSLSSSA 246
Query: 515 QGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLV 574
+ S R P PA P P Q P P G L
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP------RKDAAPALGPLS 300
Query: 575 QPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPS 634
+ P P P P P+ P P ++ P P L P + P
Sbjct: 301 SSPLATPSPS-GTKARPVPPPDNAATPLPATLPPSPP----LATPLPLAPPS-------- 347
Query: 635 YPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
P AP +L P P P +QAP + P+ Q + P P T P PP
Sbjct: 348 -PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPS 405
Query: 695 PEVVS 699
P +S
Sbjct: 406 PLALS 410
Score = 40.8 bits (94), Expect = 0.004
Identities = 88/432 (20%), Positives = 127/432 (29%), Gaps = 86/432 (19%)
Query: 337 GRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPP-- 394
G +G + ++ R+ + ++ + +P A AS PPA+ PP
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 395 ---------PDR--------PIEKK--------SYSRARRTRTKVGDAVKL-AEEVPPPP 428
P R P+ +K + +R + T A+ A P
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
Query: 429 EGLIPAP-----------------PVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNI 471
P+P P P P PPT E P S +S E + +
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT-----EGPRKSVSSASEHSTTEPSP 222
Query: 472 AEQNWSPGQPSFLQP--RELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRP 529
A + +P R L + A P + K Q RP
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
P + PL P T P P P P P P P
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKA-RPVPPPDNAATPLPATLPPSP---PLA 338
Query: 590 TPAPLPNPGLYPPP----VSMSPGQPP---PQQLLAPTYFSAPGVMNFGNPSYPY---AP 639
TP PL P PP + P PP P + P + P + P+ +P
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398
Query: 640 GALPPPPP--------------PHLYPN----TQAPSQVYGGVTYYNPAQQQVQPKPSPP 681
PP P P L T +P Q +T +P++ P SPP
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT--SPSRPASTPPDSPP 456
Query: 682 RRTPQPVTIKPP 693
+ P + PP
Sbjct: 457 LQAPLSLPASPP 468
Score = 32.0 bits (71), Expect = 2.0
Identities = 34/131 (25%), Positives = 44/131 (33%), Gaps = 1/131 (0%)
Query: 339 SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRP 398
SG + S + E+ D PE A P+ E AA P A + APP R
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 952
Query: 399 IEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSS 458
T D + E PE PAP + P+P T G A +
Sbjct: 953 APGAPLPWPPATGPGSADGLCTIYET-EGPESATPAPGALDPGPSPGTSGGKAAAGAGAG 1011
Query: 459 TSGLEQDVAQL 469
S A+L
Sbjct: 1012 ASSRSPKQARL 1022
Score = 30.0 bits (66), Expect = 7.6
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 19/112 (16%)
Query: 12 DTEDEESG--ASGS-DSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVES-- 66
+TE ES A G+ D G SP GG + AG G S P Q R G L L +++
Sbjct: 977 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ--ARLGELPLGALQASV 1034
Query: 67 -----------GGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSE 107
A+ A G EG V +A S+ E G ++E
Sbjct: 1035 VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAAL-SDAELGRWAE 1085
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 63.9 bits (154), Expect = 5e-10
Identities = 90/373 (24%), Positives = 124/373 (33%), Gaps = 99/373 (26%)
Query: 362 PSPEADAPVLGS-PEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARR---------TR 411
P P+ P S P PP P PPPP P+ +S A T
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670
Query: 412 TKVGDA--------------VKLAEEVPP----PPEGLIPAPPVPETTPTPPTKTGTWEA 453
T++ +A V ++ V P PP G++P PP P PTP +
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA------ 724
Query: 454 PVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMG 513
+AQL A +P P F P PP + ++++ +
Sbjct: 725 ------------MAQLKPAP--CAPSLPQFSAPP--------------PPLKIHQVQHI- 755
Query: 514 VQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPL---------QFQGPIYTHGDSP 564
+Q P P PP PP+ + PL + P+ T P
Sbjct: 756 ----------TQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP 804
Query: 565 APLPP-QGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFS 623
P PP QP + P P P+P P L P S PP L+P
Sbjct: 805 TPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL---PKQQSFCAKPPPSPLSPV--- 858
Query: 624 APGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRR 683
P V+ +P PPP PP + +Q V V +P + +PK P
Sbjct: 859 -PSVVKQIASQFP------PPPTPPAM--ESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Query: 684 TPQPVTIKPPPPE 696
PPPPE
Sbjct: 910 PVPSPDFPPPPPE 922
Score = 61.6 bits (148), Expect = 2e-09
Identities = 95/403 (23%), Positives = 135/403 (33%), Gaps = 66/403 (16%)
Query: 328 PVEAGGQHGGRSGETVKHEISYRSRRLEQTS---VRDPSPEADAPVLGSPEKEEAASEPP 384
P ++ G + VK+ R + Q S + P+P PV+ S + PP
Sbjct: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP----PVMQSQSVKPQILVPP 705
Query: 385 -AAAPDAAPPPPDRPIEKKSYSRARRTRT-----------------KVGDAVKLAEEVPP 426
P PPPP P + ++ + +V ++A PP
Sbjct: 706 NGVVPPPPPPPPP-PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 427 PPEGLIPAPPVPETTPTP------PTKTGT-----WEAPVDSSTSGLEQDVAQLNIAEQN 475
PP IPAP P+ P P PT T T +A + T + Q
Sbjct: 765 PPPP-IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY 823
Query: 476 WSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPA 535
P P+ P +P A PPP + K+ +SQ P PP
Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAKPPP-----SPLSPVPSVVKQIASQ----FPPPPT 874
Query: 536 PPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLP 595
PP ME P+ P SP + + + +P P P + L
Sbjct: 875 PPA----MESQPLKPV----PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926
Query: 596 NPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQ 655
P P PV P PPP P +PG S +PG PPP P + +
Sbjct: 927 FPPPPPSPVPAPPPPPPPTASPTPDKSGSPG----KKTSKTSSPGGKKPPPTPQRNSSIK 982
Query: 656 APSQVYGGVTYYNPAQQQVQ---PKPSPPRRTPQPVTIKPPPP 695
+ S G + P + V K +PP + P PPP
Sbjct: 983 SSS----GAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP 1021
Score = 55.8 bits (133), Expect = 1e-07
Identities = 72/292 (24%), Positives = 93/292 (31%), Gaps = 79/292 (27%)
Query: 424 VPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGL---EQDVAQLNIAEQN----W 476
+PPPP P PP P P PP + AP S + + + +L A Q+ +
Sbjct: 628 LPPPPP---PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684
Query: 477 SPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP 536
P P +Q + ++ G PPP P PP P
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPP--------------------------PPPPPP 718
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQT------ 590
P S M PAP P P + P P L HQ
Sbjct: 719 PTPGSAMAQL----------------KPAPCAPS----LPQFSAPPPPLKIHQVQHITQV 758
Query: 591 --PAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPP 648
P P P P P P + P PP + P S V P A PP P P
Sbjct: 759 APPTPPPPP---PIPAPLPPQAPPKPLVTIPAPTSTKTVA-------PVVTQAAPPTPTP 808
Query: 649 HLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTI-KPPPPEVVS 699
+ P + P+ Y P P P PP P+ + PPP +S
Sbjct: 809 PVPPAKKQPAFPAS----YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Score = 46.6 bits (109), Expect = 8e-05
Identities = 77/335 (22%), Positives = 109/335 (32%), Gaps = 110/335 (32%)
Query: 363 SPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAE 422
+P++ V P+ + S P +PD PPPP+ +
Sbjct: 891 APQSPPAVKAKPKWQP--SSIPVPSPDFPPPPPESSLV---------------------- 926
Query: 423 EVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPS 482
PPPP +PAPP P PPT + T P S + G + + SPG
Sbjct: 927 -FPPPPPSPVPAPP----PPPPPTASPT---PDKSGSPGKK--------TSKTSSPG--- 967
Query: 483 FLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISI 542
G PPP R + + SS + P P+ P+ +
Sbjct: 968 ----------------GKKPPPTPQRNSSI--------KSSSGAEHPEPKRPS----VDS 999
Query: 543 MEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLP---HPGLHPHQTPAPLPNPGL 599
+ + P + P PA P G L G+NLP G + P L G
Sbjct: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV-LSGRGK 1058
Query: 600 -----YPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNT 654
+P P S S PPP + P LPP P ++
Sbjct: 1059 DSVVEFPSPPSDSDFPPPPPETELP----------------------LPPIEIPAVFSGN 1096
Query: 655 QAPSQVYGGVTYYNPAQQQ---VQPKPSPPRRTPQ 686
+P V NP QQ + K +PP P+
Sbjct: 1097 TSPK-----VAVVNPQPQQWSKMSVKKAPPPTRPK 1126
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/134 (29%), Positives = 48/134 (35%), Gaps = 14/134 (10%)
Query: 566 PLPPQGMLVQP-GMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSA 624
PL PQ +V P + P P L P P P P P PPP + P AP +
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667
Query: 625 PGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRT 684
+ N S GAL PP P + + Q+ V P P PP
Sbjct: 668 STITRLQNAS--QHSGALFKPPTPPVMQSQSVKPQIL-------VPPNGVVPPPPPPPPP 718
Query: 685 PQP----VTIKPPP 694
P P +KP P
Sbjct: 719 PTPGSAMAQLKPAP 732
Score = 45.4 bits (106), Expect = 2e-04
Identities = 86/361 (23%), Positives = 128/361 (35%), Gaps = 57/361 (15%)
Query: 355 EQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKV 414
+ +S+ PSP+ P P + PP +P APPPP P A T K
Sbjct: 905 QPSSIPVPSPDFPPP----PPESSLVFPPPPPSPVPAPPPPPPPT-------ASPTPDKS 953
Query: 415 GDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQ 474
G K + P G PP P+ + + +G E P S ++ V++ +
Sbjct: 954 GSPGKKTSKTSSP--GGKKPPPTPQRNSSIKSSSGA-EHPEPKRPS-VDSLVSKFTPPAE 1009
Query: 475 NWSPGQPSFLQPRELRGMPNHIHMGA----GPPPQFNRMEEMGVQGGRAKRY-------S 523
+ SP + + L P P +++ G Q + V GR K
Sbjct: 1010 SGSPSKET-LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPP 1068
Query: 524 SQRQRPVPEP----PAPPVHI-SIMEGH------YYDPLQFQGPIYTHGDSPAPLPPQG- 571
S P P P P PP+ I ++ G+ +P Q + +P P P+
Sbjct: 1069 SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128
Query: 572 ---------MLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYF 622
+ QP M P Q P P L P ++ Q+ +
Sbjct: 1129 DSTRLTQAEISEQPTMATVVP-----QVPTS-PKSSLSVQPGFLADLNRTLQRKSITRHG 1182
Query: 623 SAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPR 682
S M+ P+ ALPPPPP L +A YGG A + P P+PP+
Sbjct: 1183 SLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAG---YGGSHISGYATLRRGPPPAPPK 1239
Query: 683 R 683
R
Sbjct: 1240 R 1240
Score = 37.7 bits (86), Expect = 0.037
Identities = 30/114 (26%), Positives = 41/114 (35%), Gaps = 21/114 (18%)
Query: 602 PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPS--- 658
P S+ P P +++ P S P P P P PPPPPP L P+ APS
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL-PSQSAPSAGS 659
Query: 659 -----------------QVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
+ G + P +Q + P+ P + PPPP
Sbjct: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713
Score = 36.6 bits (83), Expect = 0.082
Identities = 79/325 (24%), Positives = 111/325 (34%), Gaps = 63/325 (19%)
Query: 255 PRRIRKPRYGSPPQRDP--NWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRN 312
P + P PP P + +G K+ + GG PP T RN++ A
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT-PQRNSSIKSSSGAEHP 990
Query: 313 YSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISY-RSRRLEQTSVRDPSP------E 365
+ + F P + G S ET+ + + +L + V P
Sbjct: 991 EPKRPSVDSLVSKFTPP---AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047
Query: 366 ADAPVLGSPEKEEAASEP-PAAAPDAAPPPPDR-----PIE------------------- 400
A APVL K+ P P + D PPPP+ PIE
Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107
Query: 401 -----KKSYSRARR-TRTKVGDAVKLAE-EVPPPPEGLIPAPPVPETTPTPPTKTGTWEA 453
K S +A TR K D+ +L + E+ P P VP T+P
Sbjct: 1108 PQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVP-TSPK---------- 1156
Query: 454 PVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHI--HMGAGPPPQ--FNRM 509
SS S +A LN Q S + L R R P M PPP +
Sbjct: 1157 ---SSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQ 1213
Query: 510 EEMGVQGGRAKRYSSQRQRPVPEPP 534
++ G G Y++ R+ P P PP
Sbjct: 1214 QKAGYGGSHISGYATLRRGPPPAPP 1238
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.5 bits (153), Expect = 6e-10
Identities = 112/459 (24%), Positives = 154/459 (33%), Gaps = 102/459 (22%)
Query: 281 SHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSG 340
+ R G+GG P + T R A R+ K G PV + G+ SG
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPG--PVSSPGR---ASG 113
Query: 341 ETVKHEISYRSRRL--EQTSVRDPSPEA--------------DAPVLGSPE-----KEEA 379
T + + R+ E+T R + EA P G+P + A
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173
Query: 380 ASEP---PAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGL-IPAP 435
A P AP A P PP K S + + T+ A A P GL PA
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA---ARRRPSAGGGLQRPAS 230
Query: 436 PVPETTPTP---PTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGM 492
++ TP P ++G S G + +P PS +P+ L+ +
Sbjct: 231 RSLSSSATPLSSPARSG-------PSARGTPR------------APAHPSQPKPKGLQAL 271
Query: 493 -PNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPL 551
P + PP+ + +G + ++ P P APP
Sbjct: 272 RPPQV-----TPPRKDAAPALGPLS--SSPLATPSPSAPPSPSAPP-------------- 310
Query: 552 QFQGPIYTHGDSPAPLPPQG--MLVQPGMN-----LPHPGLHPHQTPAPLPNPGLYPPPV 604
+ T PA P Q L P + LP P L P TP P P L PP+
Sbjct: 311 ----SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 605 SMSPGQP--PPQQLLAPTYFSAPGVM-------NFGNPSYPYAPGALPPPPPPHLYPNTQ 655
P P PP LA AP + F P P PP P + P+
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
Query: 656 APSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
PSQ + A +Q PSPP P + PPP
Sbjct: 427 PPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPP 460
Score = 62.0 bits (149), Expect = 2e-09
Identities = 91/381 (23%), Positives = 126/381 (33%), Gaps = 57/381 (14%)
Query: 351 SRRLEQTSVRDPSPEADAP-VLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARR 409
SR L ++ SP P G+P S+P A PP P K +
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 289
Query: 410 TRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL 469
+ + PP P APP +T P+PP P +T+ L Q
Sbjct: 290 LSSS--PLATPSPSAPPSPS----APPSLQTLPSPPA------TPPSQATTSLGSPTLQA 337
Query: 470 NIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGP-PPQFNRMEEMGVQGGRAKRYSSQR-- 526
+ P P P + + A P PP + + +A +
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 527 QRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLH 586
Q P PP+PPV + + P P+ P+ PP L P + +P
Sbjct: 398 QAPFSPPPSPPV-----QAPFSPPAS--PPVSPSATPPSQAPPS--LAAPPLQVP----- 443
Query: 587 PHQTPAPLPNPGLYPPPVSMSPGQPPPQQLL-----APTYFSAPGVMNFGNP-------- 633
P +P +P PPP + P PP QL AP + P + +P
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503
Query: 634 ------SYPYAPGALPPP--PPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTP 685
S P +P A PPP PP P Q P T P + P P P
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVS 560
Query: 686 QP---VTIKPPPPEVVSRGSS 703
P + + P PP SR S
Sbjct: 561 GPRLTLALAPGPPPPPSRSPS 581
Score = 52.0 bits (123), Expect = 2e-06
Identities = 79/318 (24%), Positives = 103/318 (32%), Gaps = 62/318 (19%)
Query: 348 SYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAP-PPPDRPIEKKSYSR 406
S S L+ T PSP P+ A + PP AP + P PP P+ S
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 407 ARRTRTKVGDAVKLAEEVPPPPEGLIPAP-PVPETTPTPPTKTGTWEAPVDSSTSGLEQD 465
+ L PPP + AP P + P P+ T +AP + L+
Sbjct: 389 PNALAVHL-----LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-- 441
Query: 466 VAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQ 525
P P P + A PPPQ +
Sbjct: 442 -----------VPPSPPASPP---------MSPSATPPPQ-----------APPPLAAPP 470
Query: 526 RQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGL 585
Q P P APP + P+ PA P Q P +LP +
Sbjct: 471 LQLAKPPPQAPPALAT-------------PPLQALPSPPASFPGQAPF-SPSASLP---M 513
Query: 586 HPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPP 645
P TP P P L P + + P P L AP PG + S P AL P
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRLTLALAPG 571
Query: 646 PPPHLYPNTQAPSQVYGG 663
PPP P +++PS G
Sbjct: 572 PPP---PPSRSPSSTLSG 586
Score = 43.9 bits (102), Expect = 5e-04
Identities = 69/296 (23%), Positives = 98/296 (33%), Gaps = 73/296 (24%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLA 421
P P+A P+ P + ++PP AP A PP + + S + ++ ++
Sbjct: 458 PPPQAPPPLAAPPLQ---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514
Query: 422 EEVPPPPEGL-IPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVA--QLNIAEQNWSP 478
PPP+ + A P+ + P+PP T +AP T G + V+ +L +A P
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 479 GQPSFLQPRELRG--MPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP 536
PS L G + H P + R + G +GG A P P+
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDSGPEGGAAAS-------PPPDAELA 625
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPN 596
H + S P PP PG LP P P
Sbjct: 626 ACHPAAW-------------------SRGPAPPLAFRGAPGAPLPWP---------PATG 657
Query: 597 PGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNF----GNPSYPYAPGALPPPPPP 648
PG SA G+ G S APGAL P P P
Sbjct: 658 PG------------------------SADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 32.0 bits (71), Expect = 2.0
Identities = 34/131 (25%), Positives = 44/131 (33%), Gaps = 1/131 (0%)
Query: 339 SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRP 398
SG + S + E+ D PE A P+ E AA P A + APP R
Sbjct: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 644
Query: 399 IEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSS 458
T D + E PE PAP + P+P T G A +
Sbjct: 645 APGAPLPWPPATGPGSADGLCTIYET-EGPESATPAPGALDPGPSPGTSGGKAAAGAGAG 703
Query: 459 TSGLEQDVAQL 469
S A+L
Sbjct: 704 ASSRSPKQARL 714
Score = 30.0 bits (66), Expect = 7.6
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 19/112 (16%)
Query: 12 DTEDEESG--ASGS-DSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVES-- 66
+TE ES A G+ D G SP GG + AG G S P Q R G L L +++
Sbjct: 669 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ--ARLGELPLGALQASV 726
Query: 67 -----------GGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSE 107
A+ A G EG V +A S+ E G ++E
Sbjct: 727 VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAAL-SDAELGRWAE 777
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 63.2 bits (152), Expect = 8e-10
Identities = 97/400 (24%), Positives = 131/400 (32%), Gaps = 113/400 (28%)
Query: 316 SGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPE-ADAPVLGSP 374
SGG+ G A +P + G GG +L +D S A P L P
Sbjct: 71 SGGYGSGGAALQP-KGGLFQGG-------------VLKLRPVGAKDGSENLAGKPALQIP 116
Query: 375 EKEEAASEPPAAAPDAAPPP---------PDRP-IEKKSYSRARRTRTKVGDAVKLAEEV 424
AA PP +A P P+ P +++ S R T +K +
Sbjct: 117 SSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSA 176
Query: 425 PPPPEG--LIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPS 482
PPPP APP P + E P+ + Q PG+
Sbjct: 177 PPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPG-------------QRLHPGREG 223
Query: 483 FLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISI 542
P ++ P+ +++ GP S Q P P P P +
Sbjct: 224 PPAPPPVKPPPSPVNIRTGP--------------------SGQSLAPPPPPYRQPPGVP- 262
Query: 543 MEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPP 602
GP +S LP + H LH +TP P+ GL PP
Sbjct: 263 -----------NGPSSPTNESAPELPQR-----------HNSLH-RKTPGPVR--GLAPP 297
Query: 603 P-VSMSPG----QPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGA--LPPPPPPHLYPNTQ 655
P S SP +PPP P+ +AP P GA PPPPPP+ ++
Sbjct: 298 PPTSASPSLLSNRPPPPARDPPSRGAAPPP-----PPPVIRNGARDAPPPPPPYRMHGSE 352
Query: 656 APSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
PS+ P PP RTP PPPP
Sbjct: 353 PPSR---------------GKPPPPPSRTPAGPPPPPPPP 377
Score = 52.0 bits (123), Expect = 2e-06
Identities = 76/280 (27%), Positives = 95/280 (33%), Gaps = 63/280 (22%)
Query: 433 PAPPVPET---TPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPREL 489
PA +P + P PP + D+ +S A L + P P +P
Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDSSR-----ASLPELPRMQRPSLPDLSRPNTT 165
Query: 490 RGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP-PVHISIMEGHYY 548
A PPP G RA PP P P+H S
Sbjct: 166 SSTGMKHSSSAPPPPP---------PGRRANA-----------PPTPLPMHSS------- 198
Query: 549 DPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSP 608
+ P Y PLPP PG L HPG P P+ P P PV++
Sbjct: 199 -----KAPAYNR---EKPLPPT-----PGQRL-HPGREGPPAPPPVKPP---PSPVNIRT 241
Query: 609 GQPPPQQLLAPT---YFSAPGVMNFGNPSYPYAPGALPPPPPPH--LYPNTQAPSQVYGG 663
G P Q LAP Y PGV N PS P A P P H L+ T P +
Sbjct: 242 G--PSGQSLAPPPPPYRQPPGVPN--GPSSPTNESA-PELPQRHNSLHRKTPGPVRGLAP 296
Query: 664 VTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS 703
+ + + +P PP R P PPPP V R +
Sbjct: 297 PPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGA 336
Score = 36.6 bits (83), Expect = 0.082
Identities = 29/113 (25%), Positives = 41/113 (36%), Gaps = 17/113 (15%)
Query: 344 KHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPP-------D 396
+H +R + P P + +P L S A +PP+ PPPP D
Sbjct: 279 RHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARD 338
Query: 397 RPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTG 449
P Y ++ + + PPPP PA P P P PP + G
Sbjct: 339 APPPPPPY--------RMHGSEPPSRGKPPPPPSRTPAGPPP--PPPPPLRNG 381
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 62.4 bits (150), Expect = 1e-09
Identities = 91/378 (24%), Positives = 128/378 (33%), Gaps = 72/378 (19%)
Query: 364 PEADAPVLGSPEKEEAASEPPAAAPDAAP-----PPPDRPIEKKSYSRARRTRTKVGDAV 418
P + +L +P+ + P AA +AAP P P P A T +G
Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP-------PAVSTPLPLGLQQ 641
Query: 419 KLAEEVPPPPEGLIPAPPVPETTPTP-------PTKTGTWEAPVDSSTSGLEQDVAQLNI 471
A++ P P APP TTP P P K + P + T+ L QD Q+ +
Sbjct: 642 PQAQQPPQAPTPQAAAPP-QATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL 700
Query: 472 AEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQG-GRAKRYSSQRQRPV 530
++ QP + L +P + + A PP Q +G G + + P
Sbjct: 701 PQERSQ--QPLSAEGPHL-SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA 757
Query: 531 PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQ-PGMNLPHPGLHPHQ 589
P P P PL+ GP S LP Q L P + PHP P +
Sbjct: 758 PAPQIPAAA----------PLKGPGP-----SSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
Query: 590 TPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPP----- 644
P+ + P + P PP P F + P+ AP A P
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
Query: 645 -----------PPPPHLYP-------------NTQAPSQVYGGVTYYNPAQQQVQPKPSP 680
PP PHL P +++ P+ P Q P+P
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP 922
Query: 681 P---RRTPQPVTIKPPPP 695
P P+P PPPP
Sbjct: 923 PPTLHLVPEPAAPPPPPP 940
Score = 50.4 bits (119), Expect = 5e-06
Identities = 65/265 (24%), Positives = 89/265 (33%), Gaps = 22/265 (8%)
Query: 358 SVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDA 417
S+ +P D+P L SP S PP+ + PP + P+ +A T +
Sbjct: 778 SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI-FV 836
Query: 418 VKLAEEVPPP---PEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQ 474
++ VPPP P P PP P P G S VA +
Sbjct: 837 IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSS 896
Query: 475 NWSPGQPSFLQPRELRGMPNH-IHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEP 533
PS Q L+ P+ H PPP + + E R P P
Sbjct: 897 RLPAPTPSDFQ---LQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPAL 953
Query: 534 PAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQ-----GMLVQPGMNLPHPGLHPH 588
P P +++E + P G I + AP PQ G L P ++ G P
Sbjct: 954 PQPK---ALLERFHQVP---SGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPS 1007
Query: 589 QTPAPLPNPGLYPPPVSMSPGQPPP 613
TP P P P M+ PP
Sbjct: 1008 GTPTA---PSHAPAPAPMAATGLPP 1029
Score = 47.0 bits (110), Expect = 6e-05
Identities = 78/348 (22%), Positives = 113/348 (32%), Gaps = 82/348 (23%)
Query: 384 PAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPT 443
PA+ +APPP P T V L + P PAP +P P
Sbjct: 719 PASVIVSAPPPAQDPAPA----------TPVAKGAGLGPQAPDSQASPAPAPQIPAAAPL 768
Query: 444 PPTKTGTWEAPVDSSTSGLEQ-----DVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHM 498
+ P SS+ L D L P +P +P+ + P+ +
Sbjct: 769 --------KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS-RPQSVSRPPSEPPL 819
Query: 499 GAGPPPQ--------FNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHIS-------IM 543
PPPQ F ++GV +S P PP PP+ +
Sbjct: 820 HPCPPPQAPPTLPGIFVIQNQLGVPPP-----ASNPAPTAPGPPQPPLRPQSQPPEGPLP 874
Query: 544 EGHYYDPLQFQGPIYTHGDS----PAPLPPQGMLVQPGMNLPHPGLHPHQTPAP------ 593
+ P + + ++ PAP P L P P PH++P P
Sbjct: 875 PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP------PSQGPHKSPTPPPTLHL 928
Query: 594 LPNPGLYPPP--------VSMSPGQPPPQQLLAPTYFSAPGVM----NFGNPSYPYAPGA 641
+P P PPP + P P P+ LL + G++ G P+ P +
Sbjct: 929 VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
Query: 642 LPP--PPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQP 687
L P P + + QAPS P P P+P T P
Sbjct: 989 LGPLTSPAASVLVSGQAPSG--------TPTAPSHAPAPAPMAATGLP 1028
Score = 38.1 bits (87), Expect = 0.028
Identities = 73/359 (20%), Positives = 113/359 (31%), Gaps = 56/359 (15%)
Query: 382 EPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPP---VP 438
+PPA AAPP P + K + + + +P + L+P P +P
Sbjct: 426 QPPATTTGAAPPQPPGALSKPMSVHLLNQGSSI--VIPAQHMLPGQNQFLLPGAPAVQLP 483
Query: 439 ETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHM 498
+ P G + +G Q +A + QN + G S + H+
Sbjct: 484 QQLSALPANVGGQILAAAAPHTG-GQLIANPILTNQNLA-GPLSLGPVLAPHSGAHSAHI 541
Query: 499 GAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDP-------- 550
+ P Q + + A + +P PA P ++++G P
Sbjct: 542 LSAAPIQVGQPALFQMPVSLAAGSLPTQSQPA---PAGPAATTVLQGVTLPPSAVAMLNT 598
Query: 551 ----LQFQGPIYTHGDS-------PAPLPPQGMLVQPGMNLPHP------------GLHP 587
+Q P G++ PAP P + + L P P
Sbjct: 599 PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP 658
Query: 588 HQTPAPLPNPGLYPPPVSMSPGQPPPQ-----------QLLAPTYFSAPGVMNFGNPSYP 636
Q P P+PGL P + GQPP Q+ P S + G P
Sbjct: 659 PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG-PHLS 717
Query: 637 YAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
+ PPP P P G+ P Q P+P + P +K P P
Sbjct: 718 VPASVIVSAPPPAQDPAPATPVAKGAGL---GPQAPDSQASPAPAPQIPAAAPLKGPGP 773
Score = 37.4 bits (85), Expect = 0.048
Identities = 87/368 (23%), Positives = 115/368 (31%), Gaps = 69/368 (18%)
Query: 360 RDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRT-----KV 414
R P+P P P K + P A A P +A + T K
Sbjct: 346 RTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405
Query: 415 GDAVKLAE-EVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAE 473
G V L+ P + PP T PP G P+ S L Q + + I
Sbjct: 406 GQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPM--SVHLLNQG-SSIVIPA 462
Query: 474 QNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEP 533
Q+ PGQ FL P G P P Q + + GG+ +
Sbjct: 463 QHMLPGQNQFLLP----GAP-----AVQLPQQLSALPAN--VGGQ-----------ILAA 500
Query: 534 PAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ---- 589
AP ++ PI T+ + PL +L PH G H
Sbjct: 501 AAPHTGGQLIAN----------PILTNQNLAGPLSLGPVLA------PHSGAHSAHILSA 544
Query: 590 TPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMN-----------FGNPS---Y 635
P + P L+ PVS++ G P Q AP +A V+ P
Sbjct: 545 APIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQ 604
Query: 636 PYAPGALPPPPPPHL--YPNTQAPSQVYGGVT--YYNPAQQQVQPKPSPPRRTPQPVTIK 691
P P A P L P QAP V + P QQ P+P P T
Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664
Query: 692 PPPPEVVS 699
P P + S
Sbjct: 665 QPSPGLAS 672
Score = 35.8 bits (81), Expect = 0.14
Identities = 73/313 (23%), Positives = 101/313 (32%), Gaps = 46/313 (14%)
Query: 371 LGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRAR-RTRTKVGDAVKLAEEV----- 424
L S +A+ A D P +RP K +R+R + K+ L++ V
Sbjct: 1268 LSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTAL 1327
Query: 425 -----PPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPG 479
PPPP + P P PP TG VD + + + P
Sbjct: 1328 DPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE---RKPLGTAPHCPR 1384
Query: 480 QPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVH 539
P RE G G G P G GRA+ S P+P
Sbjct: 1385 LPLRKTYRENVG-------GPGAPE--------GTPAGRARGGS---PAPLPAKVDEATS 1426
Query: 540 ISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGL 599
I E + +Q + PA QG + PGL P + +P +
Sbjct: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQG---TGDPDWEAPGLPPAKR-RKSESPDV 1482
Query: 600 YPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGN-------PSYPYAPGALPPPPPPHLY- 651
S S P L + ++N PSYP+A A P PP L+
Sbjct: 1483 --DQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHR 1540
Query: 652 PNTQAPSQVYGGV 664
P PS GG+
Sbjct: 1541 PEAYPPSSHNGGL 1553
Score = 31.2 bits (69), Expect = 3.4
Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 28/159 (17%)
Query: 359 VRDPSPEADAPVLGSPEKEEAASEPPAAAPD-----AAPPPPDRPIEKKSYSRARRTRTK 413
V +P P P + + PP AAP+ AP P P+ +K+Y R
Sbjct: 1342 VAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPL-RKTY------REN 1394
Query: 414 VGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL-NIA 472
VG P PEG PA +P P A VD +TSGL +++A + +
Sbjct: 1395 VGG--------PGAPEG-TPAGRARGGSPAP------LPAKVDEATSGLIRELAAVEDEL 1439
Query: 473 EQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEE 511
Q G P +G + G PP R E
Sbjct: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSE 1478
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/286 (28%), Positives = 98/286 (34%), Gaps = 73/286 (25%)
Query: 422 EEVPPPPEGLIPAPPVP-ETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
+ PPPP PP + PP + G E P N S G
Sbjct: 48 QRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG---------------NQSQGP 92
Query: 481 PSFLQPRELRGMPNHI-HMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVH 539
P +P + G P + GPPP+ + E QGG +Q Q P P P P
Sbjct: 93 PP--RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGG------NQSQGPPPRPGKP--- 141
Query: 540 ISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLP---N 596
EG QG + G P P P+G Q G P HP + P P N
Sbjct: 142 ----EGP-----PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGN 192
Query: 597 PGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAP-------GALPPPPPPH 649
PPP P PPPQ G + G P P P G P PPPH
Sbjct: 193 QSQGPPPRPGKPEGPPPQ----------GGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPH 242
Query: 650 LYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
P + G P Q+ +P+ PP PQ PPPP
Sbjct: 243 -------PGKPQG-----PPPQEGNKPQRPPPPGRPQ----GPPPP 272
Score = 61.6 bits (148), Expect = 2e-09
Identities = 91/337 (27%), Positives = 113/337 (33%), Gaps = 66/337 (19%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVG 415
Q+ D S E V+ K E P PPPP +P E + +++ G
Sbjct: 17 QSLNEDVSQEESPSVISG--KPEGRRPQGGNQPQRTPPPPGKP-EGRPPQGGNQSQ---G 70
Query: 416 DAVKLAEEVPPPPEG------LIPAPPVPETTPT--------PPTKTGTWEAPVDSSTSG 461
+ + PPP+G P P PE P PP + G E P
Sbjct: 71 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGG-- 128
Query: 462 LEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHI-HMGAGPPPQFNRMEEMGVQGGRAK 520
N S G P +P + G P + GPPP+ + E QGG
Sbjct: 129 -------------NQSQGPPP--RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG--- 170
Query: 521 RYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNL 580
+Q Q P P P P EG QG + G P P P+G Q G
Sbjct: 171 ---NQSQGPPPHPGKP-------EGP-----PPQGGNQSQGPPPRPGKPEGPPPQGGNQS 215
Query: 581 ----PHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYP 636
P PG P P+ N PPP P PPPQ+ P PG P P
Sbjct: 216 QGPPPRPG-KPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG-----RPQGP 269
Query: 637 YAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQ 673
PG P P P Q P G + P Q Q
Sbjct: 270 PPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306
Score = 54.7 bits (130), Expect = 3e-07
Identities = 78/309 (25%), Positives = 105/309 (33%), Gaps = 60/309 (19%)
Query: 339 SGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPP----- 393
S +++ ++S E SV PE P G+ + + PP P+ PP
Sbjct: 15 SAQSLNEDVSQE----ESPSVISGKPEGRRPQGGNQPQR---TPPPPGKPEGRPPQGGNQ 67
Query: 394 ---PPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPP-----EGLIPAPPVPETTPT-- 443
PP RP + + +++ E PP +G P P PE P
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127
Query: 444 ------PPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPR---ELRGMPN 494
PP + G E P + + + PG+P P+ + +G P
Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR---------PGKPEGPPPQGGNQSQGPPP 178
Query: 495 HIHMGAGPPPQFNRMEE-----MGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYD 549
H GPPPQ + G G + +Q Q P P P P S
Sbjct: 179 HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPS-------- 230
Query: 550 PLQFQGPIYTHGDSPAPLPPQGMLVQPGMN--LPHPGLHPHQTPAPLPNPGLYPPPVSMS 607
QG G P P PQG Q G P P P P P NP PP +
Sbjct: 231 ----QGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGK 286
Query: 608 P-GQPPPQQ 615
P G PPP Q
Sbjct: 287 PQGPPPPPQ 295
Score = 38.1 bits (87), Expect = 0.028
Identities = 38/137 (27%), Positives = 48/137 (35%), Gaps = 18/137 (13%)
Query: 575 QPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPS 634
+P P G P +TP P P PP PPP+ G + G P
Sbjct: 35 KPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 94
Query: 635 YPYAPGALPP--------PPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPR---- 682
P P PP PPP P P GG P + +P+ PP+
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ---GGNQSQGPPPRPGKPEGPPPQGGNQ 151
Query: 683 -RTPQPVTIKP--PPPE 696
+ P P KP PPP+
Sbjct: 152 SQGPPPRPGKPEGPPPQ 168
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 62.0 bits (149), Expect = 2e-09
Identities = 87/339 (25%), Positives = 104/339 (30%), Gaps = 87/339 (25%)
Query: 364 PEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEE 423
P A P LG P PP P PPPP P + ++
Sbjct: 697 PPAFTPPLGIP--------PPGFGPGVPPPPPPPPFLRPGFNPMHL-------------- 734
Query: 424 VPPPPEGLIPAPPVPETTPT--PPTKTGTWEAP-VDSSTSGLEQDVAQLNIAEQNWSPGQ 480
PP L P PP P T P PP T P + S G + + + P
Sbjct: 735 ---PPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAA 791
Query: 481 PSFL------QPRELRGMPNHIHMGAGPPPQFN-RMEEMGVQGGRAKRYSSQRQRPVPEP 533
P+ L QP L G G P P + G+ G R QR P
Sbjct: 792 PTNLPTPPVTQPVSLLGT-----QGVAPGPVIGLQAPSTGLLGARPGLIPLQRP-----P 841
Query: 534 PAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAP 593
PP H+ PL P P+PP M H+ P P
Sbjct: 842 GMPPPHLQRF------PLM----------PPRPMPPHMM---------------HRGPPP 870
Query: 594 LPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPN 653
P PPP M PP + P G G G PP P P
Sbjct: 871 GPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQ 930
Query: 654 TQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKP 692
QAP Q QQQ Q +P PP + P P +P
Sbjct: 931 PQAPQQ----------PQQQQQQQP-PPSQQPPPTQQQP 958
Score = 49.3 bits (116), Expect = 1e-05
Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 25/119 (21%)
Query: 587 PHQTPAPLPNPGL-YPPPVSMSPGQPPPQQ-------LLAPTYFSAPGVMNFGNPSYPYA 638
P P P+P P + P P+++ P Q PP Q L P F+ P G P +
Sbjct: 657 PIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPP----LGIPPPGFG 712
Query: 639 PGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPP--PP 695
PG PPPPPP P + G + P P PP TP PV+I PP PP
Sbjct: 713 PGVPPPPPPPPFLRPGFNPMHLPPGF---------LPPGPPPP-ITP-PVSIPPPHTPP 760
Score = 44.7 bits (104), Expect = 3e-04
Identities = 50/188 (26%), Positives = 72/188 (38%), Gaps = 36/188 (19%)
Query: 515 QGGRAKRYSSQRQRPVPEP---PAPPVHISIMEGHYYDPLQFQGP-IYTHGDSPAPLPPQ 570
Q G A+ ++ P+P+P P PP+ + P+ P + H P PP
Sbjct: 643 QNGGAETSHTEPVSPIPKPLPVPVPPIPVPA-------PITVPPPQVPPH----QPGPPV 691
Query: 571 GMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTY---FSAPGV 627
+QP P G+ P P PG+ PP PPP L P + PG
Sbjct: 692 VGALQPPAFTPPLGI-----PPPGFGPGVPPP--------PPPPPFLRPGFNPMHLPPGF 738
Query: 628 MNFGNPSYPYAPGALPPP--PP---PHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPR 682
+ G P P ++PPP PP P+L + ++ V Y A P P
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798
Query: 683 RTPQPVTI 690
QPV++
Sbjct: 799 PVTQPVSL 806
Score = 38.9 bits (89), Expect = 0.016
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 30/121 (24%)
Query: 351 SRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA-PPPPDRP-------IEKK 402
S++ + T+V +P A P A+ P AAAP AA PPPP P +++
Sbjct: 277 SKKEDTTAVTTTAPAAAVP------PAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQP 330
Query: 403 SYSRAR-----RTRTKVGDAVKLAEEVPPPPEG------LIPAPPVPETT-----PTPPT 446
+Y++ + + R + +VP PP G L+P PP P PTPP
Sbjct: 331 AYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPV 390
Query: 447 K 447
+
Sbjct: 391 Q 391
Score = 35.4 bits (80), Expect = 0.18
Identities = 62/304 (20%), Positives = 97/304 (31%), Gaps = 46/304 (15%)
Query: 374 PEKEEAASEPPA-AAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVK-LAEEVPPPPEGL 431
P + +SEPP A P++ P P P + A+ +T G ++ + + PP+
Sbjct: 156 PPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPK-- 213
Query: 432 IPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRG 491
P P A V + T AQL S + +F P +
Sbjct: 214 ----------PQSPALDNAVMAQVQAIT-------AQLKTTPTQPSEQKAAFPPPEQKTA 256
Query: 492 MPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPL 551
+ +F+ +E K ++ P PP + +
Sbjct: 257 FDKKLL------DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATV-------- 302
Query: 552 QFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQP 611
P + +P PPQ PG + P HQ N + P + P
Sbjct: 303 ----PAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQ------NMDQFQPRMMGIQQDP 352
Query: 612 PPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQ 671
Q+ P PG P +P + PP PP P QA Q P Q
Sbjct: 353 MHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQP-FQASFQAQNEPLTQKPHQ 411
Query: 672 QQVQ 675
Q+++
Sbjct: 412 QEME 415
Score = 32.0 bits (71), Expect = 2.0
Identities = 43/200 (21%), Positives = 66/200 (33%), Gaps = 46/200 (23%)
Query: 356 QTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPD---AAPPPPDRPI------------- 399
Q + SP D V+ + A + P AA PPP++
Sbjct: 209 QQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYD 268
Query: 400 -EKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSS 458
E ++ +++ T A VPP P +PA P PP +AP
Sbjct: 269 DEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPP-----QAPFGFP 323
Query: 459 TSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGR 518
G++Q QN QP + ++ P H + P P +M G+
Sbjct: 324 GDGMQQPA---YTQHQNMDQFQPRMM---GIQQDPMHHQV---PLPPNGQMPGFGL---- 370
Query: 519 AKRYSSQRQRPVPEPPAPPV 538
+P PP PP+
Sbjct: 371 -----------LPTPPFPPM 379
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 62.0 bits (149), Expect = 2e-09
Identities = 60/183 (32%), Positives = 75/183 (40%), Gaps = 40/183 (21%)
Query: 524 SQRQRPVPE--PPAPPVHISIMEGHYYDPLQFQGPIYT---HGDSPA-PLPPQGMLVQPG 577
+ R+ P PE PPA P S +E + L+ +G I GD+ + + P + G
Sbjct: 455 ASRRPPEPEKAPPAAPTRPSALELKV-EELEEKGLIRILRGPGDAVSIEILPVAVATPSG 513
Query: 578 MNLPHPGL-----HPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGN 632
+ P PG+ P PA P PG PPP PG P PQ+ AP SAP
Sbjct: 514 GDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQE--APP--SAP------- 562
Query: 633 PSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKP 692
P P PG+ PPP P L + P P P PP T PV P
Sbjct: 563 PQAPPLPGSPEPPPAPPLPGDLPPP-----------------PPPPPPPPGTDGPVPPPP 605
Query: 693 PPP 695
PPP
Sbjct: 606 PPP 608
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/130 (26%), Positives = 49/130 (37%), Gaps = 27/130 (20%)
Query: 363 SPEADAPVLGSPEKEEAASEPPAAAPDAAP------PPPDRPIEKKSYSRARRTRTKVGD 416
+P P+ G P +EA PP+A P A P PPP P+ GD
Sbjct: 541 APPPPPPLPGLPSPQEA---PPSAPPQAPPLPGSPEPPPAPPLP--------------GD 583
Query: 417 AVKLAEEVPPPP--EGLIPAPPVPETTPT--PPTKTGTWEAPVDSSTSGLEQDVAQLNIA 472
PPPP +G +P PP P P PP G ++ + + + +
Sbjct: 584 LPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMP 643
Query: 473 EQNWSPGQPS 482
NW +PS
Sbjct: 644 LLNWVALKPS 653
Score = 36.6 bits (83), Expect = 0.082
Identities = 63/263 (23%), Positives = 82/263 (31%), Gaps = 86/263 (32%)
Query: 353 RLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRT 412
R E ++R+ E+ A +G+ + + P AAP P + +E+ R
Sbjct: 437 RKELETLRERFSESTA--MGASRRPPEPEKAPPAAP-TRPSALELKVEELEEKGLIRILR 493
Query: 413 KVGDAVK---LAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL 469
GDAV L V P G P P VP +P+P AP +
Sbjct: 494 GPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPP---------- 543
Query: 470 NIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRP 529
P L G+P+ PPQ + P
Sbjct: 544 ---------------PPPPLPGLPSPQEAPPSAPPQAPPLP----------------GSP 572
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
P PPAPP+ GD P P PP P P P
Sbjct: 573 EP-PPAPPL---------------------PGDLPPPPPP-----------PPP---PPG 596
Query: 590 TPAPLPNPGLYPPPVSMSPGQPP 612
T P+P P PPP PG PP
Sbjct: 597 TDGPVPPP---PPPPPPPPGGPP 616
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 62.0 bits (149), Expect = 2e-09
Identities = 77/270 (28%), Positives = 93/270 (34%), Gaps = 52/270 (19%)
Query: 422 EEVPP--PPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAE-QNWSP 478
+ VPP P GL P PP P PP S GL L AE +
Sbjct: 1311 KSVPPSVPARGLQPQPPATPAVPHPPP----------SGAFGLG---GALEAAESEGLGL 1357
Query: 479 GQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYS-SQRQRPVPEPP-AP 536
G PS + + + P F+ EE V R + S S + +PP A
Sbjct: 1358 GCPS-----PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGL-----HPHQTP 591
P S +G P+ P P P G+ P P L P P
Sbjct: 1413 PKDTSTPDGP---------PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP 1463
Query: 592 APLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLY 651
AP P P PPP P P P L+APT S P P P P A+P PPPP
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP-----PPPLPPPPPPAMPSPPPPP-- 1516
Query: 652 PNTQAPSQVYGGVTYYNPAQQQVQPKPSPP 681
P AP P ++ P P P
Sbjct: 1517 PPAAAPLAA--------PPEEPAAPSPEDP 1538
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/101 (33%), Positives = 42/101 (41%), Gaps = 27/101 (26%)
Query: 601 PPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPN------T 654
PPP + QP P LL + G P P + PPPPP L P+ +
Sbjct: 766 PPPPTAQSTQPTPHGLL----------LEAGGPDLPL----VLPPPPPQLLPSVLSHAPS 811
Query: 655 QAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
+PS GV PA + P+P PP P P PPPP
Sbjct: 812 PSPSASKVGVHLLEPATRDGAPQPPPP---PPP----PPPP 845
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/331 (24%), Positives = 104/331 (31%), Gaps = 85/331 (25%)
Query: 362 PSPEADAPVLG----SPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDA 417
PSP A +G P + A +PP P PPPP P++ +++ R+
Sbjct: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPP---PPPPPMPLQLEAHLRSHGLEPAAPSP 866
Query: 418 VKLAEEVPPPPEG-------LIPAPPVP-ETTPTPPTKTGTWEAPVDSSTSGLEQDVAQL 469
EE PP L P PP P +T PP G + P + S Q
Sbjct: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG--KDPAGAYRSPSPQGTKAP 924
Query: 470 NIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRP 529
S LQ E P MEEM GG A Y
Sbjct: 925 RFVPLTSICFPDSLLQDEERSFFPT--------------MEEM-FGGGAADDYGKA---- 965
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQ 589
GP GD A P PG P P+
Sbjct: 966 -------------------------GPPEDEGDPKAGAGPP-----PGP----PAYDPYG 991
Query: 590 TPAPLPNPGLYP--PPVSMSPGQPPPQQLLAPTYFSAP-GVMNFGNPSYPYAPGALPPPP 646
P G P P + + P +PP L T + P G++ G P PPP
Sbjct: 992 PYCPGRASGAGPETPGLGLDPNKPPE---LPSTVNAEPLGLIQSG-------PHQAAPPP 1041
Query: 647 PPHLYPNTQAPSQVYGGVTYYNPAQQQVQPK 677
PP P S+ GG+T +P +PK
Sbjct: 1042 PPPPPPPPAPASEPKGGLT--SPIFCSTKPK 1070
Score = 39.7 bits (91), Expect = 0.010
Identities = 43/154 (27%), Positives = 53/154 (34%), Gaps = 27/154 (17%)
Query: 561 GDSPAPLPPQGMLVQPGMNLPHPGL-HPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAP 619
G P P+P L P + P GL PH P+ P V S G ++L
Sbjct: 158 GSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA---PTVPSSLGF---ERLAGG 211
Query: 620 TYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYP---NTQAPSQVYGGVTYYNPAQ----Q 672
G+ P PY PG PPPPP P N A S + Q
Sbjct: 212 GVLGPAGLGPAQTP--PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 673 QVQPKPSPPRRT-----------PQPVTIKPPPP 695
P P PP R +P + +PPPP
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPP 303
Score = 38.9 bits (89), Expect = 0.016
Identities = 30/105 (28%), Positives = 35/105 (33%), Gaps = 26/105 (24%)
Query: 594 LPNPGLYPPPVSMSPGQPPPQQLLA----PTYFSAPGVMNFGNPSYPYAPGALPPPPPPH 649
L +P L P + +P PP A P P + G P P PP PPP
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464
Query: 650 LYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPP 694
P QP+P PP PQP PPP
Sbjct: 1465 PTP----------------------QPQPPPPPPPPQPALPSPPP 1487
Score = 38.5 bits (88), Expect = 0.021
Identities = 30/100 (30%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 346 EISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYS 405
E S R Q S+ D P L P+ PP A A P PP P + S
Sbjct: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
Query: 406 RARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPP 445
L EE PPP P P P+ P PP
Sbjct: 1445 NGT-------PEPPLLEEKPPPTP---PPAPTPQPQPPPP 1474
Score = 37.7 bits (86), Expect = 0.037
Identities = 68/290 (23%), Positives = 91/290 (31%), Gaps = 50/290 (17%)
Query: 361 DPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPD-------RP-IEKKSYSRARRTRT 412
+PSP A P P A + A P+AA RP I+ Y
Sbjct: 338 EPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTG----- 392
Query: 413 KVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIA 472
K G PPP P +T TP K + P + +G
Sbjct: 393 KGGYGAAAGGATRPPP---------PRSTATP--KCQSLGGPAAAYATGKASGAG--GAG 439
Query: 473 EQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSS--QRQRPV 530
Q +SPGQP L + G G GG+A+ S
Sbjct: 440 GQAYSPGQPQGLLGPQAYG--------------------QGFGGGQAQDLSKAPSYSGGP 479
Query: 531 PEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQT 590
P+PP+ P + Y P Q QG +Y P P P P + P +
Sbjct: 480 PQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTAS-PSLSYSTGHS 538
Query: 591 PAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPG 640
PA + G + P G+ P ++ P S P P APG
Sbjct: 539 PALSGHGGGWGPSSLGGGGEASPSHIIRPLQ-SPPATGRPPGVGSPGAPG 587
Score = 37.4 bits (85), Expect = 0.048
Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 636 PYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPP 695
P AP A P PPP P PS G T P ++ P PP TPQP PPPP
Sbjct: 1423 PLAPAAAVPGPPP--LPGL--PSANSNG-TPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP 1477
Score = 37.0 bits (84), Expect = 0.063
Identities = 25/104 (24%), Positives = 35/104 (33%), Gaps = 31/104 (29%)
Query: 362 PSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLA 421
P+P+ P P + S PP AP + PPP
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP------------------------- 1499
Query: 422 EEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQD 465
+PPPP +P+PP P PP AP + + +D
Sbjct: 1500 -PLPPPPPPAMPSPP-----PPPPPAAAPLAAPPEEPAAPSPED 1537
Score = 32.3 bits (72), Expect = 1.5
Identities = 42/166 (25%), Positives = 58/166 (34%), Gaps = 31/166 (18%)
Query: 360 RDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVK 419
R P P + +P +S PP AP A PP P+ P K
Sbjct: 1669 RPPVPVRRSGQAKNPVSAGGSSAPPPKAP-APPPKPETP-------------------EK 1708
Query: 420 LAEEVPP--PPEGLIPAPPVPE----TTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAE 473
E PP PE +P PP PE P K + G + E
Sbjct: 1709 TTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPE 1768
Query: 474 QNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRA 519
++ + GQP+ R + P + A PPP+ R + + GG A
Sbjct: 1769 RSLATGQPA--TSRLPKARPTKVK--AEPPPK-KRKKWLKEAGGNA 1809
Score = 30.8 bits (68), Expect = 4.5
Identities = 37/147 (25%), Positives = 54/147 (36%), Gaps = 26/147 (17%)
Query: 357 TSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAA---PPPPDRPI-------EKKSYSR 406
+S P A P +PEK + +PP P+ A PP P++P EK+
Sbjct: 1689 SSAPPPKAPAPPPKPETPEKTT-SEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKV 1747
Query: 407 ARRTRTKVGDAVKLAEEVPP--------PPEGLIP-APPVPETTPTPPTKTGTW--EAPV 455
R R G+ + P P +P A P PP K W EA
Sbjct: 1748 TRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGG 1807
Query: 456 DSSTSGLEQDVAQLNIAEQNWSPGQPS 482
+++ G + ++ SPG PS
Sbjct: 1808 NATAGGGPPG----SSSDSESSPGAPS 1830
Score = 30.4 bits (67), Expect = 5.9
Identities = 44/198 (22%), Positives = 63/198 (31%), Gaps = 49/198 (24%)
Query: 445 PTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPP 504
P G+ PV SS L++ + +SP L P ++ +H+ P
Sbjct: 154 PASFGSRPFPVPSS----------LSLQDPPFSPPANGLLSPHDV------LHLKPSQAP 197
Query: 505 Q------FNRMEEMGVQG--GRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPL----- 551
F R+ GV G G + + P+PP PP H+
Sbjct: 198 TVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAA 257
Query: 552 --QFQGPIYTH-GDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSP 608
Q +Y G +P P PP+ L + + H Y P S P
Sbjct: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH-----------------YQRPASAQP 300
Query: 609 GQPPPQQLLAPTYFSAPG 626
PPP Y S G
Sbjct: 301 PPPPPPAHALQHYLSCGG 318
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 60.5 bits (145), Expect = 5e-09
Identities = 86/323 (26%), Positives = 114/323 (35%), Gaps = 32/323 (9%)
Query: 339 SGETVKHEISYR-SRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDA--APPPP 395
S + + ++S S L + + PSP+ G P PP + PPPP
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74
Query: 396 DRPIEKKSYS-RARRTRTKVGDAVKLAEEVPPPPEGLIPA--PPVPETTPTPPTKTGTWE 452
+P ++R R+ G + PPP G P PP P PP + G
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-- 127
Query: 453 APVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHI-HMGAGPPPQFNRMEE 511
P G Q +++ SP P P + +G P + GPPP + +
Sbjct: 128 RPQGPPPPGKPQGPPPQG--DKSRSPRSP----PGKPQGPPPQGGNQPQGPPPPPGKPQG 181
Query: 512 MGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSP-APLPPQ 570
QGG+ Q P +P PP P + QGP G+ P P PP
Sbjct: 182 PPPQGGK----KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Query: 571 GMLVQP---GMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQP--PPQQLLAPTYFSAP 625
G P G N P P + P G PG+P PPQQ P
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ--EGNNPQGP 295
Query: 626 GVMNFGNPSYPYAPGALPPPPPP 648
GNP P AP A P PP
Sbjct: 296 PPPAGGNPQQPQAPPAGQPQGPP 318
Score = 53.5 bits (127), Expect = 6e-07
Identities = 83/345 (24%), Positives = 108/345 (31%), Gaps = 88/345 (25%)
Query: 365 EADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEV 424
E+ + + G+P+ S P PPPP +P +
Sbjct: 27 ESPSLIAGNPQ---GPSPQGGNKPQGPPPPPGKP------------------------QG 59
Query: 425 PPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFL 484
PPP G P P P P P G +++ SP P
Sbjct: 60 PPPQGGNKPQGPPPPGKPQGPPPQG-----------------------DKSRSPRSP--- 93
Query: 485 QPRELRGMPNHI-HMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIM 543
P + +G P + GPPP + + QGG Q P +P PP
Sbjct: 94 -PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP----QGPPPPGKPQGPPPQGDKS 148
Query: 544 EGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYP-- 601
P + QGP G+ P PP P + P P G P
Sbjct: 149 RSPRSPPGKPQGPPPQGGNQPQGPPPP----------------PGKPQGPPPQGGKKPQG 192
Query: 602 PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVY 661
PP P PPPQ + + S PG P P PPPP P Q ++
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Query: 662 G----GVTYYNPAQ-----QQVQPKPSPPRRTPQPVTIKP--PPP 695
G G PAQ Q + P P+ PQ P PPP
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297
Score = 48.9 bits (115), Expect = 2e-05
Identities = 63/244 (25%), Positives = 79/244 (32%), Gaps = 36/244 (14%)
Query: 457 SSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQG 516
SS L +DV+Q PS + P + GPPP + + QG
Sbjct: 14 SSAQNLNEDVSQEE---------SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG 64
Query: 517 GRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQP 576
G Q P +P PP P + QGP G+ P PP
Sbjct: 65 GN----KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP------ 114
Query: 577 GMNLPHPGLHPHQTPAPLPNPGLYP--PPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPS 634
P + P P G P PP P PPPQ + + S PG P
Sbjct: 115 ----------PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 164
Query: 635 YPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKP-- 692
P PPPP P Q + G P + Q P R+ Q KP
Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP---PGKPQGPPPQGDKSRSSQSPPGKPQG 221
Query: 693 PPPE 696
PPP+
Sbjct: 222 PPPQ 225
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 60.1 bits (144), Expect = 7e-09
Identities = 64/191 (33%), Positives = 72/191 (37%), Gaps = 50/191 (26%)
Query: 530 VPEPPAPPVHISIMEGHYYDPLQFQGPIYT-HGDS-PAPLPPQGMLVQPGMNL------- 580
+P PP PP GH G + HG S P P PP GM PGM+
Sbjct: 261 MPPPPMPPG----AAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGM-PHPGMSQMQLAHHG 315
Query: 581 PHPGLHPHQ-------TPAPLPNPGLY---PPPVSMSPGQPPPQQLLAPTYFSAPGVMNF 630
PH HPH P P P PG+ PPP+ M P PP F +P M
Sbjct: 316 PHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPP---------FGSP--MGH 364
Query: 631 GNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTI 690
P P+ PP PPH Y P P Q P P PPR TP+P
Sbjct: 365 PGPMPPHGMRGPPPLMPPHGYTGPPRPP----------PYGYQRGPLP-PPRPTPRP--- 410
Query: 691 KPPPPEVVSRG 701
P PP RG
Sbjct: 411 -PVPPRGPLRG 420
Score = 45.1 bits (105), Expect = 2e-04
Identities = 68/264 (25%), Positives = 91/264 (34%), Gaps = 46/264 (17%)
Query: 372 GSPEKEEAASEPPAAAPDA-------APPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEV 424
GS + A++ P + D APPPP P S + + V
Sbjct: 188 GSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPV 247
Query: 425 PPP---PEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPG-- 479
PPP P G+ PA P P P PP G P + T G + + PG
Sbjct: 248 PPPGALPPGIPPAMPPP---PMPPGAAG--HGPPSAGTPGAGHP-GHGHSHPHPFPPGGM 301
Query: 480 -QPSFLQPRELRGMPNHI-HMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRP-VPEPPAP 536
P Q + P+ + H AGPP GG+ R P +P P P
Sbjct: 302 PHPGMSQMQLAHHGPHGLGHPHAGPPGS----------GGQPP----PRPPPGMPHPGPP 347
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPN 596
P+ + + P+ P P+PP GM P + PH P + P
Sbjct: 348 PMGMPPRGPPFGSPM----------GHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQ 397
Query: 597 PGLYPPP-VSMSPGQPPPQQLLAP 619
G PPP + P PP L P
Sbjct: 398 RGPLPPPRPTPRPPVPPRGPLRGP 421
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/112 (32%), Positives = 39/112 (34%), Gaps = 25/112 (22%)
Query: 587 PHQTPAPLPNPGLYPPPVSMS-------PGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAP 639
PHQ A P P P PV S PG PPP P PG + G P P
Sbjct: 207 PHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPV--PPPGALPPGIP-----P 259
Query: 640 GALPPPPPP----HLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQP 687
PPP PP H P+ P + P P P PP P P
Sbjct: 260 AMPPPPMPPGAAGHGPPSAGTPGAGH-------PGHGHSHPHPFPPGGMPHP 304
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/342 (24%), Positives = 111/342 (32%), Gaps = 88/342 (25%)
Query: 372 GSPEKEEAASEPP----AAAPDAAPPP---PDRPIEKKSYSRARRTRTKVGDAVKLAEEV 424
G PE + PP + PD+ PPP RPI+ ++R
Sbjct: 160 GPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS---------------- 203
Query: 425 PPPPEGLIPAPPVPETTPTP-PTKTGTW-------EAPVDSSTSGLEQDVAQLNIAEQNW 476
PP P G P P P TP P P GT ++P+ SS+ + +
Sbjct: 204 PPVPGG--PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD 261
Query: 477 SPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAP 536
P P + P+ IH A PPP + R +S + P P PP+
Sbjct: 262 DKPPPP---PPPVGNRPS-IHREAVPPPPPQNNKPPVPSTPRPS--ASSQAPPPPPPPSR 315
Query: 537 PVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPN 596
P P PLPP LP L + PLP+
Sbjct: 316 P-------------------------GPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Query: 597 PGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQA 656
PG P PPP + P PG G LPPPPP +T
Sbjct: 351 PG------RSGPLPPPPSERPPPPVRDPPG-----------RSGPLPPPPPVSRNGSTSR 393
Query: 657 PSQVYGGVTYYNPAQQQV---QPKPSPPRRTPQPVTIKPPPP 695
T P++ V + P PP +P PPPP
Sbjct: 394 ALP----ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPP 431
Score = 57.4 bits (137), Expect = 4e-08
Identities = 100/417 (23%), Positives = 124/417 (29%), Gaps = 106/417 (25%)
Query: 303 GTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDP 362
G G + GGF G G GG GG + +L T+ RD
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGGGG----GGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119
Query: 363 SPEADAPVLGSPEKEEAASEP--PAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKL 420
P L P +++P P + P P P P + +R R
Sbjct: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS--PGHRSGPPEPQRNRM-------- 169
Query: 421 AEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQ 480
PPP + + P P P T P+ SS SP
Sbjct: 170 -----PPPRPDVGSKPDSIPPPVPSTPR-----PIQSSP-------------HNRGSPPV 206
Query: 481 PSFLQPRELRGMPNHIHMGAGPPP-QFNRMEEMGVQGGRAKRYSSQRQRPVPE-PPAPPV 538
P G P G PPP NR +G GG ++ P PP PP
Sbjct: 207 P---------GGPRQPSPGPTPPPFPGNRGTALG--GGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 539 HISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPG 598
P D P P PP P N P +H P P P
Sbjct: 256 -----------------PSRALDDKPPPPPP------PVGN--RPSIHREAVPPPPPQNN 290
Query: 599 LYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPS 658
PPV +P Q P P P PG PPP PP N + P
Sbjct: 291 --KPPVPSTPRPSASSQAPPP-------------PPPPSRPG--PPPLPPSSSGNDETPR 333
Query: 659 QVYGGVTYYN-----PAQQQVQPKPSPPRRTPQPVTIKPP-------PPEVVSRGSS 703
++ + P+ + P P PP P P PP PP VSR S
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGS 390
Score = 56.2 bits (134), Expect = 1e-07
Identities = 87/371 (23%), Positives = 122/371 (32%), Gaps = 87/371 (23%)
Query: 328 PVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAA 387
P GG G T R L S+R + +P P P+ A
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT----PSRA 259
Query: 388 PDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETT------ 441
D PPPP P VG+ + E PPP PPVP T
Sbjct: 260 LDDKPPPPPPP---------------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS 304
Query: 442 -----PTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHI 496
P PP++ G P SS + + Q N++ + +P PS P +P
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS---PGRSGPLP--- 358
Query: 497 HMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGP 556
PPP +RP P PP PL P
Sbjct: 359 -----PPPS---------------------ERPPPPVRDPPGRSG--------PLPPPPP 384
Query: 557 IYTHGDSPAPLPPQGMLV-QPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQ 615
+ +G + LP L + G++ P G P PLP P + +P PPP
Sbjct: 385 VSRNGSTSRALPATPQLPSRSGVDSPRSGPRP-----PLPPDR----PSAGAPPPPPPST 435
Query: 616 LLAPTYFSAPGVMNFGNPSYPYAPGALPPPPP----PHLYPNTQAPSQVYGGVTYYNPAQ 671
+ + +P + + Y + LPPP P YP+ A ++ G N +
Sbjct: 436 SIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSG---SNRRE 492
Query: 672 QQVQPKPSPPR 682
+ P P PR
Sbjct: 493 RGAPPLPPIPR 503
Score = 33.5 bits (75), Expect = 0.69
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 12/67 (17%)
Query: 15 DEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSL----PSQRGG--RTGALHLRRV---- 64
D+ GA G+ GG GGG G GGGG GS P GG + G LR
Sbjct: 60 DKPKGA-GAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRD 118
Query: 65 -ESGGAK 70
+SGG++
Sbjct: 119 NDSGGSR 125
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.131 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,024,288
Number of Sequences: 37866
Number of extensions: 3098737
Number of successful extensions: 45053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 579
Number of HSP's successfully gapped in prelim test: 1926
Number of HSP's that attempted gapping in prelim test: 19223
Number of HSP's gapped (non-prelim): 16188
length of query: 703
length of database: 18,247,518
effective HSP length: 109
effective length of query: 594
effective length of database: 14,120,124
effective search space: 8387353656
effective search space used: 8387353656
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.