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Search of human proteins with 156627581
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 790 0.0
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 69 7e-12
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 68 2e-11
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 65 1e-10
gi|156616308 SET and MYND domain containing 4 [Homo sapiens] 64 2e-10
gi|27262638 sperm associated antigen 1 [Homo sapiens] 63 5e-10
gi|27262636 sperm associated antigen 1 [Homo sapiens] 63 5e-10
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 62 1e-09
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 58 1e-08
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 57 2e-08
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 57 4e-08
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 56 5e-08
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 56 5e-08
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 56 5e-08
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 54 2e-07
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens] 54 2e-07
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 54 2e-07
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 53 5e-07
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 51 2e-06
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 49 6e-06
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 49 6e-06
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 48 1e-05
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 48 1e-05
gi|4503729 FK506 binding protein 52 [Homo sapiens] 47 2e-05
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 47 4e-05
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 46 5e-05
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 46 5e-05
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 46 5e-05
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom... 46 5e-05
gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens] 46 6e-05
>gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
Length = 387
Score = 790 bits (2040), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MEQPGQDPTSDDVMDSFLEKFQSQPYRGGFHEDQWEKEFEKVPLFMSRAPSEIDPRENPD 60
MEQPGQDPTSDDVMDSFLEKFQSQPYRGGFHEDQWEKEFEKVPLFMSRAPSEIDPRENPD
Sbjct: 1 MEQPGQDPTSDDVMDSFLEKFQSQPYRGGFHEDQWEKEFEKVPLFMSRAPSEIDPRENPD 60
Query: 61 LACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY 120
LACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY
Sbjct: 61 LACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY 120
Query: 121 TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI 180
TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI
Sbjct: 121 TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI 180
Query: 181 DAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACED 240
DAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACED
Sbjct: 181 DAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACED 240
Query: 241 EDSASEGLGELFLDGLSTENPHGARLSLDGQGRLSWPVLFLYPEYAQSDFISAFHEDSRF 300
EDSASEGLGELFLDGLSTENPHGARLSLDGQGRLSWPVLFLYPEYAQSDFISAFHEDSRF
Sbjct: 241 EDSASEGLGELFLDGLSTENPHGARLSLDGQGRLSWPVLFLYPEYAQSDFISAFHEDSRF 300
Query: 301 IDHLMVMFGETPSWDLEQKYCPDNLEVYFEDEDRAELYRVPAKSTLLQVLQHQRYFVKAL 360
IDHLMVMFGETPSWDLEQKYCPDNLEVYFEDEDRAELYRVPAKSTLLQVLQHQRYFVKAL
Sbjct: 301 IDHLMVMFGETPSWDLEQKYCPDNLEVYFEDEDRAELYRVPAKSTLLQVLQHQRYFVKAL 360
Query: 361 TPAFLVCVGSSPFCKNFLRGRKVYQIR 387
TPAFLVCVGSSPFCKNFLRGRKVYQIR
Sbjct: 361 TPAFLVCVGSSPFCKNFLRGRKVYQIR 387
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 68.9 bits (167), Expect = 7e-12
Identities = 65/226 (28%), Positives = 100/226 (44%), Gaps = 20/226 (8%)
Query: 35 WEKEFEKVPLFMSRAPSEIDPRENPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKD 94
+E EK F +A E +AC + + K K++GN FKE +
Sbjct: 166 YEDCIEKAVQFFVQALRMAPDHEKACIACRNA----------KALKAKKEDGNKAFKEGN 215
Query: 95 YKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAI 154
YK A YTE L + NA LY NR L A+ D T A KL ++KA
Sbjct: 216 YKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAY 275
Query: 155 IRGALCHLELKHFAEAVNWCDEGLQID-AKEKKLLEMRAKADKLKRIEQRDVRK------ 207
+R A C+++ + + EAV ++ Q + KE K L A+ + LK+ +++D K
Sbjct: 276 LRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLE-LKKSKRKDYYKILGVDK 334
Query: 208 -ANLKEKKERNQNEALLQAIKARNIRLSEAACEDEDSASEGLGELF 252
A+ E K+ + AL+ + +E E+E E +GE F
Sbjct: 335 NASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKE-VGEAF 379
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 8/100 (8%)
Query: 116 NAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCD 175
NA Y NRAA LG FR AL D + +L ++ +R CHL L + A
Sbjct: 5 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 64
Query: 176 EGLQIDAKEKKLLEMRAKADKLKR--------IEQRDVRK 207
L++D K + + A+ + E+RD RK
Sbjct: 65 RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRK 104
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 67.8 bits (164), Expect = 2e-11
Identities = 64/226 (28%), Positives = 100/226 (44%), Gaps = 20/226 (8%)
Query: 35 WEKEFEKVPLFMSRAPSEIDPRENPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKD 94
+E EK F +A E +AC + + K K++GN FKE +
Sbjct: 222 YEDCIEKAVQFFVQALRMAPDHEKACIACRNA----------KALKAKKEDGNKAFKEGN 271
Query: 95 YKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAI 154
YK A YTE L + NA LY NR L A+ D T A KL ++KA
Sbjct: 272 YKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAY 331
Query: 155 IRGALCHLELKHFAEAVNWCDEGLQID-AKEKKLLEMRAKADKLKRIEQRDVRK------ 207
+R A C+++ + + EAV ++ Q + KE K L A+ + L++ +++D K
Sbjct: 332 LRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLE-LRKSKRKDYYKILGVDK 390
Query: 208 -ANLKEKKERNQNEALLQAIKARNIRLSEAACEDEDSASEGLGELF 252
A+ E K+ + AL+ + +E E+E E +GE F
Sbjct: 391 NASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKE-VGEAF 435
Score = 67.4 bits (163), Expect = 2e-11
Identities = 46/155 (29%), Positives = 74/155 (47%), Gaps = 13/155 (8%)
Query: 61 LACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY 120
+A + + D++ + E A+T+K++GN Y+ +KDY +A YT+ + C NA Y
Sbjct: 11 MAATEPELLDDQEAKRE-AETFKEQGNAYYAKKDYNEAYNYYTKAIDM-CPK---NASYY 65
Query: 121 TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI 180
NRAA LG FR AL D + +L ++ +R CHL L + A L++
Sbjct: 66 GNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL 125
Query: 181 DAKEKKLLEMRAKADKLKR--------IEQRDVRK 207
D K + + A+ + E+RD RK
Sbjct: 126 DHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRK 160
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 64.7 bits (156), Expect = 1e-10
Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 6/121 (4%)
Query: 63 CLQSIIFDEERSPEEQAKT--YKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY 120
C ++ PE+ K KDEGN++ KE++Y AV YT+ ++ DP+ NAV Y
Sbjct: 67 CKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIE---LDPN-NAVYY 122
Query: 121 TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI 180
NRAAAQ LG++ A+ D A + + KA R L L F EAV + L +
Sbjct: 123 CNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL 182
Query: 181 D 181
D
Sbjct: 183 D 183
>gi|156616308 SET and MYND domain containing 4 [Homo sapiens]
Length = 804
Score = 64.3 bits (155), Expect = 2e-10
Identities = 48/178 (26%), Positives = 89/178 (50%), Gaps = 22/178 (12%)
Query: 82 YKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVT 141
Y++EGN F+EKDY A + Y++G+ + + ++ + NR+AA ++LG + + L D+
Sbjct: 71 YREEGNKKFQEKDYTGAAVLYSKGVSHSRPNTEDMSLCHANRSAALFHLGQYETCLKDIN 130
Query: 142 AAR------KLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKAD 195
A+ +L+P K ++R A C + L EA I E+ A AD
Sbjct: 131 RAQTHGYPERLQP---KIMLRKAECLVALGRLQEA------SQTISDLERNFTATPALAD 181
Query: 196 KLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACEDED----SASEGLG 249
L + QR++ + +K +++ + E+ A+ L +AA +E+ +AS +G
Sbjct: 182 VLPQTLQRNLHRLKMKMQEKDSLTESFPAALAK---TLEDAALREENEQLSNASSSIG 236
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 62.8 bits (151), Expect = 5e-10
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 76 EEQAKTYKDEGNDYFKEKDYKKAVISYTEGLK---KKCADPDLNAVLYTNRAAAQYYLGN 132
E+ K K+EGN +K+YK A+ Y+E LK K+CA +YTNRA L
Sbjct: 620 EKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-------IYTNRALCYLKLCQ 672
Query: 133 FRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRA 192
F A D A +L ++KA R AL H LK++ +++ ++ + +D ++E +
Sbjct: 673 FEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLD---PSIIEAKM 729
Query: 193 KADKLKRIEQRDVRKANLKEKKERNQNE 220
+ +++ R+ + A ++KER + E
Sbjct: 730 ELEEVTRLLNLKDKTAPFNKEKERRKIE 757
Score = 55.8 bits (133), Expect = 6e-08
Identities = 56/238 (23%), Positives = 105/238 (44%), Gaps = 26/238 (10%)
Query: 19 EKFQSQPYRGGFHED--QWEK-EFEKVPLFMSRAPSEIDPRENPDLACLQSIIFDEERSP 75
EK+ +P + D +W+K + EK L + E + L+ +++ I +
Sbjct: 143 EKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAGLTE 202
Query: 76 EEQ---AKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGN 132
+E+ A K++GN+ F DY++AV+ YT + A P + V Y NRA A+ L N
Sbjct: 203 KEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSIS---ALPTV--VAYNNRAQAEIKLQN 257
Query: 133 FRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI----DAKEKKLL 188
+ SA D +L+P ++KA++R A + EA + L + D +K L
Sbjct: 258 WNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLS 317
Query: 189 EMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACEDEDSASE 246
E+ +RD++ + + + ++Q I+ ++ + ED +
Sbjct: 318 EV-----------ERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGD 364
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 83 KDEGNDYFKEKDYKKAVISYTEGLK------KKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
K +GN+ F+ + +A Y+ + + AD DL+ +LY+NRAA GN
Sbjct: 449 KSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIAD-DLS-ILYSNRAACYLKEGNCSGC 506
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQID 181
+ D A +L P +K ++R A+ + L+ + +A LQID
Sbjct: 507 IQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 62.8 bits (151), Expect = 5e-10
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 76 EEQAKTYKDEGNDYFKEKDYKKAVISYTEGLK---KKCADPDLNAVLYTNRAAAQYYLGN 132
E+ K K+EGN +K+YK A+ Y+E LK K+CA +YTNRA L
Sbjct: 620 EKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECA-------IYTNRALCYLKLCQ 672
Query: 133 FRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRA 192
F A D A +L ++KA R AL H LK++ +++ ++ + +D ++E +
Sbjct: 673 FEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLD---PSIIEAKM 729
Query: 193 KADKLKRIEQRDVRKANLKEKKERNQNE 220
+ +++ R+ + A ++KER + E
Sbjct: 730 ELEEVTRLLNLKDKTAPFNKEKERRKIE 757
Score = 55.8 bits (133), Expect = 6e-08
Identities = 56/238 (23%), Positives = 105/238 (44%), Gaps = 26/238 (10%)
Query: 19 EKFQSQPYRGGFHED--QWEK-EFEKVPLFMSRAPSEIDPRENPDLACLQSIIFDEERSP 75
EK+ +P + D +W+K + EK L + E + L+ +++ I +
Sbjct: 143 EKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKIETRIDTAGLTE 202
Query: 76 EEQ---AKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGN 132
+E+ A K++GN+ F DY++AV+ YT + A P + V Y NRA A+ L N
Sbjct: 203 KEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSIS---ALPTV--VAYNNRAQAEIKLQN 257
Query: 133 FRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI----DAKEKKLL 188
+ SA D +L+P ++KA++R A + EA + L + D +K L
Sbjct: 258 WNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLS 317
Query: 189 EMRAKADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACEDEDSASE 246
E+ +RD++ + + + ++Q I+ ++ + ED +
Sbjct: 318 EV-----------ERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGD 364
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 83 KDEGNDYFKEKDYKKAVISYTEGLK------KKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
K +GN+ F+ + +A Y+ + + AD DL+ +LY+NRAA GN
Sbjct: 449 KSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIAD-DLS-ILYSNRAACYLKEGNCSGC 506
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQID 181
+ D A +L P +K ++R A+ + L+ + +A LQID
Sbjct: 507 IQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 61.6 bits (148), Expect = 1e-09
Identities = 59/204 (28%), Positives = 101/204 (49%), Gaps = 34/204 (16%)
Query: 32 EDQWEKE--------FEKVPLFMSRAPSEIDPRENPD----------LACLQSIIFDEER 73
EDQ E+E FE+ P +++ + N D L L+ + DEE+
Sbjct: 55 EDQGEEECFHDCSASFEEEP-----GADKVENKSNEDVNSSELDEEYLIELEKNMSDEEK 109
Query: 74 SPEEQAKT-YKDEGNDYFKEKDYKKAVISYTEGLKK--KCADPDLNAVLYTNRAAAQYYL 130
+ T K+EGN+ FK+ DY +A SY+ L+ C + ++L++NRAAA+
Sbjct: 110 QKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKE-RSILFSNRAAARMKQ 168
Query: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEM 190
A+ND + A +L P +++AI+R A + + EA+ ++ I K+ + +
Sbjct: 169 DKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEAL---EDYKSILEKDPSIHQA 225
Query: 191 RAKADKL-KRIEQRDVRKANLKEK 213
R +L K+IE+R+ R LKE+
Sbjct: 226 REACMRLPKQIEERNER---LKEE 246
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
E+A+ K+EGN+ K+ ++KKA+ Y+E L C+ +L + Y+NRA L + A
Sbjct: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESL--LCS--NLESATYSNRALCYLVLKQYTEA 246
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMR 191
+ D T A KL ++KA R A H LK + + LQI+ + ++R
Sbjct: 247 VKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLR 301
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Query: 86 GNDYFKEKDYKKAVISYTEGLK----KKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVT 141
GN+ F+ Y +A Y L+ + +DP+ +VLY+NRAA GN R + D T
Sbjct: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
Query: 142 AARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQID 181
+A L P +K ++R A + L+ + A LQID
Sbjct: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 11/110 (10%)
Query: 74 SPEEQAKTY----KDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAA--- 126
SP+ + Y K + N+ F + + +A+ Y++ +++ NA+LY NRAAA
Sbjct: 352 SPQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRA----PHNAMLYGNRAAAYMK 407
Query: 127 QYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDE 176
+ + G+ AL D A L PCHLKA R A C ELK+ AEA+ D+
Sbjct: 408 RKWDGDHYDALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDD 457
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 56.6 bits (135), Expect = 4e-08
Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 4/104 (3%)
Query: 83 KDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTA 142
K++GN+ F++ DY +A+ YTE +K+ D A LY+NRAA L F+ AL D
Sbjct: 364 KNKGNECFQKGDYPQAMKHYTEAIKRNPKD----AKLYSNRAACYTKLLEFQLALKDCEE 419
Query: 143 ARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKK 186
+L+P +K R A +K + +A++ + L +D+ K+
Sbjct: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKE 463
Score = 48.9 bits (115), Expect = 8e-06
Identities = 38/113 (33%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EQ K++GN + A+ Y+E +K DP N VLY+NR+AA G+++ A
Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIK---LDPH-NHVLYSNRSAAYAKKGDYQKA 57
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLE 189
D LKP K R A L F EA +EGL+ +A +L E
Sbjct: 58 YEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKE 110
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 24/126 (19%)
Query: 79 AKTYKDEGNDYFKEKDYKKAVISYTEGLK--------KKC---------------ADPDL 115
AK Y GN YFKE+ YK A+ Y + L KKC +PDL
Sbjct: 300 AKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDL 359
Query: 116 NAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCD 175
A+ N+ + G++ A+ T A K P K A C+ +L F A+ C+
Sbjct: 360 -ALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCE 418
Query: 176 EGLQID 181
E +Q++
Sbjct: 419 ECIQLE 424
Score = 35.0 bits (79), Expect = 0.11
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 71 EERSPE--EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQY 128
EE PE +QA K+ GND +K+KD+ A+ Y K K DP N TN+AA +
Sbjct: 215 EEDLPENKKQALKEKELGNDAYKKKDFDTALKHYD---KAKELDP-TNMTYITNQAAVYF 270
Query: 129 YLGNF 133
G++
Sbjct: 271 EKGDY 275
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 56.2 bits (134), Expect = 5e-08
Identities = 47/149 (31%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
++A K++GN YFK+ Y +A+ YT+G+ ADP N VL TNRA+A + L F A
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMD---ADP-YNPVLPTNRASAYFRLKKFAVA 186
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKE-KKLLEMRAKAD 195
+D A L + KA R L+ EA + L+++ + E+R +
Sbjct: 187 ESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQ 246
Query: 196 KLKRIEQRDVRKANLKEKK---ERNQNEA 221
L E ++A++ K ER Q EA
Sbjct: 247 ALASKENSYPKEADIVIKSTEGERKQIEA 275
Score = 53.1 bits (126), Expect = 4e-07
Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 71 EERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYL 130
E + ++QA + KD GN +FKE Y++A+ YT G+ A NA+L NRA A +
Sbjct: 274 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGI----AADGANALLPANRAMAYLKI 329
Query: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEM 190
+ A D T A L + KA R L EA + L ++ K+ +
Sbjct: 330 QKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAV-- 387
Query: 191 RAKADKLKRIEQRDVRKANLKE 212
+L +I+++ ++K ++E
Sbjct: 388 ----TELSKIKKKPLKKVIIEE 405
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 56.2 bits (134), Expect = 5e-08
Identities = 47/149 (31%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
++A K++GN YFK+ Y +A+ YT+G+ ADP N VL TNRA+A + L F A
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMD---ADP-YNPVLPTNRASAYFRLKKFAVA 186
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKE-KKLLEMRAKAD 195
+D A L + KA R L+ EA + L+++ + E+R +
Sbjct: 187 ESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQ 246
Query: 196 KLKRIEQRDVRKANLKEKK---ERNQNEA 221
L E ++A++ K ER Q EA
Sbjct: 247 ALASKENSYPKEADIVIKSTEGERKQIEA 275
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 71 EERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYL 130
E + ++QA + KD GN +FKE Y++A+ YT G+ A NA+L NRA A +
Sbjct: 274 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGI----AADGANALLPANRAMAYLKI 329
Query: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEM 190
+ A D T A L + KA R L EA + L ++ K+ +
Sbjct: 330 QKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTE 389
Query: 191 RAKADK 196
+K K
Sbjct: 390 LSKIKK 395
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 56.2 bits (134), Expect = 5e-08
Identities = 43/181 (23%), Positives = 87/181 (48%), Gaps = 11/181 (6%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLN-AVLYTNRAAAQYYLGNFRS 135
++A+ K++GN YFK Y++A+ YTE + + +++ + Y NRAAA L ++
Sbjct: 112 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKE 171
Query: 136 ALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKAD 195
D T A +L P ++KA+ R A H +L + E + ++ + + + AD
Sbjct: 172 VAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQ--QSMLLAD 229
Query: 196 KLKRIEQRDVRKANLKEKKERNQNEALLQA--------IKARNIRLSEAACEDEDSASEG 247
K+ ++ ++ K K ++ + +++ I ++ + E + ED+D E
Sbjct: 230 KVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEA 289
Query: 248 L 248
L
Sbjct: 290 L 290
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 54.3 bits (129), Expect = 2e-07
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 71 EERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYL 130
EE S E A+ K EGN+ K ++++ AV Y + ++ A NAV + NRAAA L
Sbjct: 85 EEDSAE--AERLKTEGNEQMKVENFEAAVHFYGKAIELNPA----NAVYFCNRAAAYSKL 138
Query: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQID 181
GN+ A+ D A + P + KA R L L EAV + + L++D
Sbjct: 139 GNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELD 189
>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
Length = 977
Score = 54.3 bits (129), Expect = 2e-07
Identities = 58/213 (27%), Positives = 89/213 (41%), Gaps = 37/213 (17%)
Query: 85 EGNDYFKEKDYKKAVISYTEGLK--------KKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EGND F+EKDYK+A++ Y EGL + +L L+ NRAA + +G + A
Sbjct: 42 EGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKA 101
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLEL---KHFAEAVNWCDEGLQIDAKEKKLLEMRAK 193
L D A L ++A+ R A EL K E + C L D
Sbjct: 102 LEDSEKALGLDSESIRALFRKARALNELGRHKEAYECSSRCSLALPHD------------ 149
Query: 194 ADKLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIRLSEAACEDEDSASEGLGELFL 253
+ + ++ Q +K L+ +K + + L N AA + S GLG +
Sbjct: 150 -ESVTQLGQELAQKLGLRVRKAYKRPQELETFSLLSN---GTAAGVADQGTSNGLGS--I 203
Query: 254 DGLSTE---NPHGARLSLDGQGRLSWPVLFLYP 283
D + T+ +P G+ L S P + L+P
Sbjct: 204 DDIETDCYVDPRGSPALLP-----STPTMPLFP 231
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/144 (28%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 79 AKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALN 138
A K++GN+ F E +Y+ A++ Y+EGL+K D+ VLYTNRA A L ++ AL
Sbjct: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKL---KDMK-VLYTNRAQAYMKLEDYEKALV 161
Query: 139 DVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLK 198
D A K KA +L LK+++ + + L+I+ K + +++ +++
Sbjct: 162 DCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQ--TQVKGYLNQVD 219
Query: 199 RIEQRDVRKANLKEKKERNQNEAL 222
E+ D+++ E + +N A+
Sbjct: 220 LQEKADLQEKEAHELLDSGKNTAV 243
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 52.8 bits (125), Expect = 5e-07
Identities = 36/146 (24%), Positives = 74/146 (50%), Gaps = 6/146 (4%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
++A+ K + NDYFK KDY+ A+ Y++ ++ + NA+ Y NR+ A + A
Sbjct: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS----NAIYYGNRSLAYLRTECYGYA 81
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADK 196
L D T A +L ++K R A ++ L F A+ + +++ +K + +K
Sbjct: 82 LGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNK 141
Query: 197 LKRIEQRDVRKANLKEKKERNQNEAL 222
+ ++Q+ +A ++ +R+ ++L
Sbjct: 142 I--VKQKAFERAIAGDEHKRSVVDSL 165
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 51.2 bits (121), Expect = 2e-06
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 71 EERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYL 130
E + ++QA + KD GN +FKE Y++A+ YT G+ A NA+L NRA A +
Sbjct: 115 EAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGI----AADGANALLPANRAMAYLKI 170
Query: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEM 190
+ A D T A L + KA R L EA + L ++ K+ +
Sbjct: 171 QKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTE 230
Query: 191 RAKADK 196
+K K
Sbjct: 231 LSKIKK 236
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 49.3 bits (116), Expect = 6e-06
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Query: 76 EEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRS 135
E +A K+EGN +F+ +DYK A SY++ L K D L A LY NRAA ++
Sbjct: 3 EVEAVQLKEEGNRHFQLQDYKAATNSYSQAL-KLTKDKALLATLYRNRAACGLKTESYVQ 61
Query: 136 ALNDVTAARKLKPCHLKAIIR--GALCHL 162
A +D + A + +KA+ R AL HL
Sbjct: 62 AASDASRAIDINSSDIKALYRRCQALEHL 90
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 49.3 bits (116), Expect = 6e-06
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Query: 76 EEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRS 135
E +A K+EGN +F+ +DYK A SY++ L K D L A LY NRAA ++
Sbjct: 3 EVEAVQLKEEGNRHFQLQDYKAATNSYSQAL-KLTKDKALLATLYRNRAACGLKTESYVQ 61
Query: 136 ALNDVTAARKLKPCHLKAIIR--GALCHL 162
A +D + A + +KA+ R AL HL
Sbjct: 62 AASDASRAIDINSSDIKALYRRCQALEHL 90
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 85 EGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAAR 144
+ N + D+ A++ Y E L DP N +LY+NR+AA + + AL+D AR
Sbjct: 64 QSNQACHDGDFHTAIVLYNEAL---AVDPQ-NCILYSNRSAAYMKIQQYDKALDDAIKAR 119
Query: 145 KLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLL 188
L P KA R + L A+A+ GL D K +LL
Sbjct: 120 LLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLL 163
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 5/121 (4%)
Query: 78 QAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSAL 137
+A + EGN ++E+ + A++ Y E +K D +LY+NR+ + L + +AL
Sbjct: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDH----LLYSNRSQIYFTLESHENAL 297
Query: 138 NDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKL 197
+D A KL+P KA R A L EA+ + +D K K+ A+ D L
Sbjct: 298 HDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKR-ARCEAQRDNL 356
Query: 198 K 198
+
Sbjct: 357 E 357
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 36/181 (19%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EQ+ K+ G YFKE YK+A++ Y KK +L S
Sbjct: 268 EQSTIVKERGTVYFKEGKYKQALLQY-----KKIVS----------------WLEYESSF 306
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKAD- 195
N+ A+K + L + + A+CHL+L+ F+ A+ C++ L++D+ +K L R +A
Sbjct: 307 SNE--EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHL 364
Query: 196 -----KLKRIEQRDVRKANLKEKKERNQNEALLQAIKARNIR-------LSEAACEDEDS 243
+L R + + V + K + Q Q I+ + R + E E+E+
Sbjct: 365 AVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENK 424
Query: 244 A 244
A
Sbjct: 425 A 425
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 46.6 bits (109), Expect = 4e-05
Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 20/153 (13%)
Query: 58 NPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNA 117
N D+A L + +EE++PE KD+GN F ++Y A+ +Y ++ P
Sbjct: 274 NTDIAELCDLK-EEEKNPE----WLKDKGNKLFATENYLAAINAYNLAIRLNNKMP---- 324
Query: 118 VLYTNRAAAQYYLGNFRSALNDVTAARKL--------KPCHLKAIIRGALCHLELKHFAE 169
+LY NRAA L N A+ D + A +L +KA +R +L+ + E
Sbjct: 325 LLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVE 384
Query: 170 AVNWCDEGLQIDAKEKKLLEMRAKADKLKRIEQ 202
+ + L+ID K ++ A+K++ + Q
Sbjct: 385 GLQDYEAALKIDPSNK---IVQIDAEKIRNVIQ 414
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 46.2 bits (108), Expect = 5e-05
Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 46/202 (22%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EQA K++G YFK Y +AVI Y + + +Y L S
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGK---------------IVSWLEMEYGLSEKESK 310
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMR----- 191
++ L A + A+C+L+L+ + +AV CD+ L +D+ +K L R
Sbjct: 311 ASESFL--------LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
Query: 192 -------AKADKLKRIEQRDVRKAN-------LKEKKERNQNEALLQAIKARNIRLSEAA 237
AK D K +E KA K+ KE N+ + + A N+ A
Sbjct: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYA----NMFKKFAE 418
Query: 238 CEDEDSASEGLGELFLDGLSTE 259
+ ++ A++ +G+ +G++ E
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNE 440
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 46.2 bits (108), Expect = 5e-05
Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 46/202 (22%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EQA K++G YFK Y +AVI Y + + +Y L S
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGK---------------IVSWLEMEYGLSEKESK 310
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMR----- 191
++ L A + A+C+L+L+ + +AV CD+ L +D+ +K L R
Sbjct: 311 ASESFL--------LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
Query: 192 -------AKADKLKRIEQRDVRKAN-------LKEKKERNQNEALLQAIKARNIRLSEAA 237
AK D K +E KA K+ KE N+ + + A N+ A
Sbjct: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYA----NMFKKFAE 418
Query: 238 CEDEDSASEGLGELFLDGLSTE 259
+ ++ A++ +G+ +G++ E
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNE 440
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 46.2 bits (108), Expect = 5e-05
Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 46/202 (22%)
Query: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
EQA K++G YFK Y +AVI Y + + +Y L S
Sbjct: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGK---------------IVSWLEMEYGLSEKESK 310
Query: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMR----- 191
++ L A + A+C+L+L+ + +AV CD+ L +D+ +K L R
Sbjct: 311 ASESFL--------LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
Query: 192 -------AKADKLKRIEQRDVRKAN-------LKEKKERNQNEALLQAIKARNIRLSEAA 237
AK D K +E KA K+ KE N+ + + A N+ A
Sbjct: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYA----NMFKKFAE 418
Query: 238 CEDEDSASEGLGELFLDGLSTE 259
+ ++ A++ +G+ +G++ E
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNE 440
>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
sapiens]
Length = 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 58 NPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNA 117
N D+A L + +EE++PE KD+GN F ++Y A+ +Y ++ P
Sbjct: 274 NTDIAELCDLK-EEEKNPE----WLKDKGNKLFATENYLAAINAYNLAIRLNNKMP---- 324
Query: 118 VLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHF 167
+LY NRAA L N A+ D + A ++ HL+ I L L L+ F
Sbjct: 325 LLYLNRAACHLKLKNLHKAIEDSSKAYRIMKRHLRLIHPTKLYKLMLRRF 374
>gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens]
Length = 333
Score = 45.8 bits (107), Expect = 6e-05
Identities = 37/166 (22%), Positives = 78/166 (46%), Gaps = 5/166 (3%)
Query: 87 NDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKL 146
+D ++D + A+ T+ L++K PD +A Y RA LGN+ A+ D + +L
Sbjct: 19 SDALIDEDPQAALEELTKALEQK---PD-DAQYYCQRAYCHILLGNYCVAVADAKKSLEL 74
Query: 147 KPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLKRIEQRDVR 206
P + A++R +C K++A A+ EG ++D+ + + + + + +V
Sbjct: 75 NPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDSADANFSVWIKRCQEAQNGSESEVW 134
Query: 207 KANLKEKKERNQNEA-LLQAIKARNIRLSEAACEDEDSASEGLGEL 251
K K + Q E+ ++ + +N++ ++ E + L +L
Sbjct: 135 THQSKIKYDWYQTESQVVITLMIKNVQKNDVNVEFSEKELSALVKL 180
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,109,415
Number of Sequences: 37866
Number of extensions: 694238
Number of successful extensions: 2946
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2728
Number of HSP's gapped (non-prelim): 249
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.