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Search of human proteins with 110431354
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110431354 transducer of regulated CREB protein 3 isoform a
[Homo sapiens]
(619 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110431354 transducer of regulated CREB protein 3 isoform a [H... 1254 0.0
gi|110431352 transducer of regulated CREB protein 3 isoform b [H... 1248 0.0
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap... 340 2e-93
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 283 4e-76
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 277 2e-74
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 7e-07
gi|105990535 coagulation factor V precursor [Homo sapiens] 52 1e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 2e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 51 4e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 6e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 8e-06
gi|239756297 PREDICTED: hypothetical protein [Homo sapiens] 49 1e-05
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 49 1e-05
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 49 1e-05
gi|50345997 E1A binding protein p300 [Homo sapiens] 49 2e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 48 2e-05
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled... 47 4e-05
gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ... 47 7e-05
gi|55750053 atrophin-1 [Homo sapiens] 47 7e-05
gi|55750041 atrophin-1 [Homo sapiens] 47 7e-05
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 46 1e-04
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 45 2e-04
gi|236459851 ubinuclein 2 [Homo sapiens] 45 2e-04
gi|112421108 capicua homolog [Homo sapiens] 45 2e-04
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 45 3e-04
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 44 4e-04
gi|54792138 helicase with zinc finger domain [Homo sapiens] 44 4e-04
gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 44 4e-04
gi|33186895 selenoprotein V [Homo sapiens] 44 4e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 44 6e-04
>gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo
sapiens]
Length = 619
Score = 1254 bits (3246), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG
Sbjct: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
Query: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG
Sbjct: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG
Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR
Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM
Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL
Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT
Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ
Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN
Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
Query: 541 CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 600
CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD
Sbjct: 541 CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 600
Query: 601 SSMGLLDPSVEETFRADRL 619
SSMGLLDPSVEETFRADRL
Sbjct: 601 SSMGLLDPSVEETFRADRL 619
>gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo
sapiens]
Length = 618
Score = 1248 bits (3229), Expect = 0.0
Identities = 618/619 (99%), Positives = 618/619 (99%), Gaps = 1/619 (0%)
Query: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG
Sbjct: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
Query: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG
Sbjct: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG
Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR
Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM
Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL
Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT
Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ
Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN
Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
Query: 541 CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 600
CGSLPNTILP DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD
Sbjct: 541 CGSLPNTILP-DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 599
Query: 601 SSMGLLDPSVEETFRADRL 619
SSMGLLDPSVEETFRADRL
Sbjct: 600 SSMGLLDPSVEETFRADRL 618
>gi|32171215 CREB regulated transcription coactivator 2 [Homo
sapiens]
Length = 693
Score = 340 bits (873), Expect = 2e-93
Identities = 271/710 (38%), Positives = 353/710 (49%), Gaps = 115/710 (16%)
Query: 2 AASPGSGSA---NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQ-QLRLTQ 57
A PGS +A NPRKFSEKIAL QRQAEET AFE++M D+ +R+Q QKL+ +
Sbjct: 6 ANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSS 65
Query: 58 YHGGSLPNVSQLRSSASEFQPSFHQA-DNVRGTRHHGLVERPSRN---RFHPLHRRSGDK 113
++GGSLPNV+Q+ S +EFQ H D+ R TRHHGLVER R+ PL R +
Sbjct: 66 HYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT--- 122
Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKD---EKHPGFRLTSALNRTNSDSALHTSA 170
R D S + Y S P + SW R+ W + EK FRL SALNRT+SDSALHTS
Sbjct: 123 --RHIDSSPYSPAYLSPPPESSW-RRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV 179
Query: 171 LSTKPQDPYGGGGQ-SAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLW 229
++ PQD Y G S P+ G DGE + P EENLL+ K L K W
Sbjct: 180 MNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV-------PAIEENLLD-DKHLLKP-W 230
Query: 230 ETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPAS 289
+ K++ S S RPRSC+V G N FP Q + +NTGGSLPDLTNLH+ PLP
Sbjct: 231 DAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP 290
Query: 290 LDTTDHHFGSMSVGNSVNNIPAAMTHLGIR---------SSSGLQSSRSNPSIQATLNKT 340
LD + + S+S GNS +N+ MTHLGI + GL S S+PS+Q++L+
Sbjct: 291 LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP 350
Query: 341 VLSSSLN--------NHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPS--------- 383
L +SL+ +H S+P +S L SL +PSLS LS S
Sbjct: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410
Query: 384 ---------------RRRQPPVSPLTLSPGP----EAHQGFSRQLSSTSPLAPYPTSQMV 424
R+ P+SPL+L GP + Q +Q S T +Q V
Sbjct: 411 LGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGV 470
Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAP------QELTQPLLQQPRAPE------------ 466
D S+LS Q PP PY +P Q T LQQP P
Sbjct: 471 PLDTSKLS------TDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524
Query: 467 -------------APAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAF 513
P+ Q + P SDF L + S+ + + D GP F
Sbjct: 525 PGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGF 584
Query: 514 -PQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLP--E 570
+ P+ G ++ H + S GS PN IL DSS K++ +ALAG+P E
Sbjct: 585 LGGEGPM--GGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFE 642
Query: 571 VS-LNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
VS ++ LE+EL++EPL L+GLNMLSD L DP+VEE+FR+DRL
Sbjct: 643 VSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692
>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
[Homo sapiens]
Length = 634
Score = 283 bits (723), Expect = 4e-76
Identities = 237/681 (34%), Positives = 315/681 (46%), Gaps = 120/681 (17%)
Query: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG
Sbjct: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63
Query: 62 SLPNVSQLRSSASE--FQPSFHQA--DNVRGTRHHGLVERP--SRNRFHPLHRR--SGDK 113
SLPNV+Q+ S + FQ F + D R TRHHGLV+R R R HRR S DK
Sbjct: 64 SLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDK 123
Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALST 173
GRQ D +G Y S P D SW RTNSDSALH S ++
Sbjct: 124 HGRQADSCPYGTMYLSPPADTSW---------------------RRTNSDSALHQSTMTP 162
Query: 174 KPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKE 233
+ + G Q + + + PG EE K L KQ W+TK+
Sbjct: 163 TQPESFSSGSQDVHQKRVL------------LLTVPG--MEETTSEADKNLSKQAWDTKK 208
Query: 234 IQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
S RP+SC+V G N FP Q + T NTGGSLPDLTN+H+ +PLP LD
Sbjct: 209 TGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPE 265
Query: 294 DHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQT 352
+ F ++S +S N+ A +THLGI + G+ + S+P + LS S Q
Sbjct: 266 EPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRPAGVSPLSLSTEARRQQ 324
Query: 353 SVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQL 409
+ P S L P + ++ SL + +QPP P P P A
Sbjct: 325 ASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPA-------- 376
Query: 410 SSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAPQELTQPLLQQPRAP-- 465
S P P P + + L LP+ + + PPP P L Q + P P
Sbjct: 377 SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSM 434
Query: 466 -----EAPAQQ---PQAASSLPQSDFQLLPAQG----------SSLTNFFPDVGFDQQ-S 506
APA Q A S QS + QG S+L + F D ++QQ +
Sbjct: 435 GIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMA 494
Query: 507 MRPGPAFPQQVPLVQQGSRELQDSFHLRPSP--------------------------YSN 540
R A Q+ + S P Y++
Sbjct: 495 ARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYAS 554
Query: 541 CGSLPNTIL--PEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNML 598
+PN IL +S SL K+L S+LAG+ +VS + D+ FPL +EL+I+PL+LDGL+ML
Sbjct: 555 HSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL-DELKIDPLTLDGLHML 613
Query: 599 SDSSMGLLDPSVEETFRADRL 619
+D M L DP+ E+TFR DRL
Sbjct: 614 NDPDMVLADPATEDTFRMDRL 634
>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
[Homo sapiens]
Length = 650
Score = 277 bits (709), Expect = 2e-74
Identities = 239/697 (34%), Positives = 317/697 (45%), Gaps = 136/697 (19%)
Query: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG
Sbjct: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63
Query: 62 SLPNVSQLRSSASE--FQPS----------------FHQA--DNVRGTRHHGLVERP--S 99
SLPNV+Q+ S + FQPS F + D R TRHHGLV+R
Sbjct: 64 SLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRE 123
Query: 100 RNRFHPLHRR--SGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSAL 157
R R HRR S DK GRQ D +G Y S P D SW
Sbjct: 124 RGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSW--------------------- 162
Query: 158 NRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENL 217
RTNSDSALH S ++ + + G Q + + + PG EE
Sbjct: 163 RRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVL------------LLTVPG--MEETT 208
Query: 218 LNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDL 277
K L KQ W+TK+ S RP+SC+V G N FP Q + T NTGGSLPDL
Sbjct: 209 SEADKNLSKQAWDTKKTGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDL 265
Query: 278 TNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQAT 336
TN+H+ +PLP LD + F ++S +S N+ A +THLGI + G+ + S+P
Sbjct: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRP 324
Query: 337 LNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPL 393
+ LS S Q + P S L P + ++ SL + +QPP P
Sbjct: 325 AGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQ 384
Query: 394 TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAP 451
P P A S P P P + + L LP+ + + PPP P
Sbjct: 385 PPPPPPPA--------SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVP 434
Query: 452 QELTQPLLQQPRAP-------EAPAQQ---PQAASSLPQSDFQLLPAQG----------S 491
L Q + P P APA Q A S QS + QG S
Sbjct: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494
Query: 492 SLTNFFPDVGFDQQ-SMRPGPAFPQQVPLVQQGSRELQDSFHLRPSP------------- 537
+L + F D ++QQ + R A Q+ + S P
Sbjct: 495 TLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT 554
Query: 538 -------------YSNCGSLPNTIL--PEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 582
Y++ +PN IL +S SL K+L S+LAG+ +VS + D+ FPL
Sbjct: 555 GSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL- 613
Query: 583 EELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
+EL+I+PL+LDGL+ML+D M L DP+ E+TFR DRL
Sbjct: 614 DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.1 bits (126), Expect = 7e-07
Identities = 50/176 (28%), Positives = 74/176 (42%), Gaps = 13/176 (7%)
Query: 329 SNPSIQATLNKTV--LSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRR 386
++P +Q +L+ V LSS L HP ++ + ++ P L SL P L T + P +
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 387 QPPVSPLTLSP-------GPEAHQGFSRQLSSTS-PLAPYPTSQMVSSDRSQLSFLPTEA 438
PP S LT P P Q S L++ P P + + S L+ P E
Sbjct: 525 TPPAS-LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 439 QAQVSPPPPYPAPQELTQPLLQQPRAPEAP--AQQPQAASSLPQSDFQLLPAQGSS 492
+ ++ PPP P + PL P P +P PQA L Q P+ +S
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Score = 51.6 bits (122), Expect = 2e-06
Identities = 86/312 (27%), Positives = 116/312 (37%), Gaps = 66/312 (21%)
Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362
G S P A H GLQ+ R PQ + P A P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRP--------------------PQVTPPRKDAA-P 294
Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVS------PLTLSPGPEAHQGFSRQLSSTSPLA 416
+L LS+ L+T + SG R PP P TL P P L+ SP A
Sbjct: 295 ALG--PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--LAPPSPSA 350
Query: 417 PYPTSQMVSSDRS--------QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAP 468
P P+ Q + S + ++ P +A + PP P LT P LQ P +P A
Sbjct: 351 P-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA- 408
Query: 469 AQQPQAASSLPQSDFQ-------LLPAQ-GSSLTNFFPDVGFDQQSMRPGPAFPQQVPLV 520
QA +SL Q + P Q +SLT+ + + P + P Q PL
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS------PSRPASTPPDSPPLQAPLS 462
Query: 521 QQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFP 580
S LQ S SP S+ P TI P + L+S + P+ L+ P
Sbjct: 463 LPASPPLQTSLSPAVSPLSS----PLTIHP-------LQALSSLASHSPQAPLSSLIMPP 511
Query: 581 LEEELQIEPLSL 592
LE + + P SL
Sbjct: 512 LETQSSLAPPSL 523
Score = 45.8 bits (107), Expect = 1e-04
Identities = 71/270 (26%), Positives = 100/270 (37%), Gaps = 39/270 (14%)
Query: 263 PFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSS 322
P L+ S P T+L + P S T H ++S + ++ P A I
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVS-PLSSPLTIHPLQALS--SLASHSPQAPLSSLIMPPL 512
Query: 323 GLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS--LSNPSLSTTNLS 380
QSS + PS+Q +SL P ++P+ + P L+ S L+ P L T
Sbjct: 513 ETQSSLAPPSLQTP------PASLTTPPLENLPSLAP--PPLQTASAPLTTPHLETPPCP 564
Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
P + PP SPLT +P PE + P P L LP+ +
Sbjct: 565 APCPLQAPP-SPLT-TPPPETPSSIATPPPQAPPALASPP----------LQGLPSPPLS 612
Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500
++ PPP AP L P LQ P +P A A+ PQ+ L V
Sbjct: 613 PLATPPP-QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------------V 658
Query: 501 GFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
Q P P+ P Q P S + S
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Score = 44.3 bits (103), Expect = 3e-04
Identities = 58/212 (27%), Positives = 79/212 (37%), Gaps = 22/212 (10%)
Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQ 441
PS PP+SPL +P P+A + L +P +P P+ + Q F P A
Sbjct: 634 PSPPASPPLSPLA-TPSPQAPNALAVHLLQ-APFSPPPSPPV------QAPFSPP-ASPP 684
Query: 442 VSPP--PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPD 499
VSP PP AP L P LQ P P PA P + S+ P P ++ P
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQ---APPPLAAPPLQVPP 739
Query: 500 VGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFK 559
M P P +VP + + PSP ++ P P + +L
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAA-----PPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 560 DLNSALAGLPEVSLNVDTPFPLEEELQIEPLS 591
AL P S PF L + PL+
Sbjct: 795 PPLQALPS-PPASFPGQAPFSPSASLPMSPLA 825
Score = 36.6 bits (83), Expect = 0.070
Identities = 83/322 (25%), Positives = 119/322 (36%), Gaps = 48/322 (14%)
Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363
AA T +G+ + S+R P + K+V S+S ++ + S P+A P+
Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSP-------LA 416
R S S LS+ SGPS R P P P+ Q R T P L
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RPPQVTPPRKDAAPALG 297
Query: 417 PYPTSQMVSSDRSQLSFLPTEAQAQVSPPP-----PYPAPQELTQPLLQQ-PRAPEAPAQ 470
P +S + + P+ +A+ PPP P PA + PL P AP +P+
Sbjct: 298 PLSSSPLATPS-------PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 471 QPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
P Q LP+ ++ + P M+ P+ Q +P +Q S
Sbjct: 351 PP---------SLQTLPSPPATPPSQAPP-SMTTPPMQAPPSL-QTIPPIQVPHSLTSPS 399
Query: 531 FHLRPSPYSNCGSLPNTIL--PEDSSTSLFKDLN--SALAGLPEVSLNVDTPFPLEEELQ 586
PSP + T L P +T F ++ A L S TP P LQ
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQ 458
Query: 587 IEPLSLDGLNMLSDSSMGLLDP 608
PLSL L S + P
Sbjct: 459 -APLSLPASPPLQTSLSPAVSP 479
Score = 34.3 bits (77), Expect = 0.35
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 9/112 (8%)
Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPY------PTSQMVSSDRSQLSFLP 435
PS P+SPL P P+A + P P P S S S L+ P
Sbjct: 770 PSPPASLPMSPLA-KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 436 TEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
+A ++ P P P LQ PR P P P + S P+ L P
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAP 878
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 52.4 bits (124), Expect = 1e-06
Identities = 116/503 (23%), Positives = 188/503 (37%), Gaps = 73/503 (14%)
Query: 137 PRQQPPWKDEKHPGF-----RLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPY 191
PR P + E + F + + L+++N +++L T T P +G W A
Sbjct: 1045 PRTFHPLRSEAYNTFSERRLKHSLVLHKSN-ETSLPTDLNQTLPSMDFG------WIASL 1097
Query: 192 MGFCDGENNGHGEVASFPGPLK----EENLLNVPKPLPKQLWETKEIQSLSGRPRSCDV- 246
+N G+ + PG + EE+ P P Q+ T + S P ++
Sbjct: 1098 PDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHSTSDPSHRSSSPELSEML 1157
Query: 247 ---GGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVG 303
+FP + + S T S PDL+ + S L + + D ++S
Sbjct: 1158 EYDRSHKSFPTDISQMSPSSEHEVWQTVIS-PDLSQVTLSPELSQTNLSPDLSHTTLSPE 1216
Query: 304 NSVNNIPAAMTHLGIR---SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
N+ A+ + I S + L S+ ++ L++T LS L+ + L
Sbjct: 1217 LIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSPELSQTNLSPALGQMPL 1276
Query: 361 HPSLRLFSLS-----------------NPSLSTTNLSGPSRRRQPPVSP----LTLSPGP 399
P L +LS +P LS TNLS Q P+SP TLS
Sbjct: 1277 SPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLS--PALGQMPISPDLSHTTLSLD- 1333
Query: 400 EAHQGFSRQLSSTS--------PLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAP 451
+ S +LS T+ PL+P P+ +S D SQ + P +Q +SP +
Sbjct: 1334 FSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELSQTNLSPD---LSE 1390
Query: 452 QELTQPLLQQPRAPEAPAQQPQAASSLPQSDF-----QLLPAQGSSLTNFFPDVGF---- 502
L L Q P P+ Q + L ++D Q+ + S PD+
Sbjct: 1391 MPLFADLSQIPLTPD--LDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSPDISDTTLL 1448
Query: 503 -DQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDL 561
D + P P Q+ + S+ L PY + G +P+ P + T L K+
Sbjct: 1449 PDLSQISPPPDL-DQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPSSPTLNDTFLSKEF 1507
Query: 562 NS-ALAGLPEVSLNVDTPFPLEE 583
N + GL + + P EE
Sbjct: 1508 NPLVIVGLSKDGTDYIEIIPKEE 1530
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/215 (29%), Positives = 83/215 (38%), Gaps = 41/215 (19%)
Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSR----SNPSIQATLNKTVLSSSLNNHPQTSVPNAS 358
G S P A H GLQ+ R + P A LSSS P S P +
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 359 ALHPSLRLFS---LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ- 408
+ PSL+ + PS +TT+L P+ + PP+SPL +P P+A +
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPP 365
Query: 409 -LSSTSPLAPYPTSQMVSSDRS----------QLSFLPTEA---QAQVSPP--------- 445
+ SP A P S + + Q F P + QA SPP
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 446 -PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLP 479
PP AP L P LQ P P PA P + S+ P
Sbjct: 426 TPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATP 458
Score = 40.4 bits (93), Expect = 0.005
Identities = 60/222 (27%), Positives = 82/222 (36%), Gaps = 29/222 (13%)
Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
+ GLQ S + + T LSS + P + HPS + +L +
Sbjct: 221 AGGGLQRPASR---SLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQV 276
Query: 380 SGPSRRRQPPVSPLTLSP----GPEAHQGFSRQLS-STSPLAPY-PTSQMVSSDRSQL-- 431
+ P + P + PL+ SP P A S S T P P P SQ +S S
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336
Query: 432 ---SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPA 488
SFLP+ + ++ PPP AP L P LQ P +P A A+ PQ+ L
Sbjct: 337 ATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-- 393
Query: 489 QGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
V Q P P+ P Q P S + S
Sbjct: 394 -----------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Score = 37.7 bits (86), Expect = 0.032
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 28/160 (17%)
Query: 353 SVPNASALHPSLRLFSLSNPSLSTTNLS-GPSRRRQPPVSPLTLSPGPEAHQGFSR---Q 408
S P + + PS S + PSL+ L PS PP+SP + +P P+A + Q
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQ 472
Query: 409 LSSTSPLAP---------------------YPTSQMVSSDRSQLSFLPTEAQAQVSPPPP 447
L+ P AP P S S S L+ P +A ++ P
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532
Query: 448 YPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
P P LQ PR P P P + S P+ L P
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAP 570
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 50.8 bits (120), Expect = 4e-06
Identities = 74/240 (30%), Positives = 88/240 (36%), Gaps = 35/240 (14%)
Query: 346 LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLT----LSPGPEA 401
LN H S P ALH +L S PS L P R P VSP L P P
Sbjct: 851 LNQHAVVSPP---ALHNALPQ-QPSRPSNRAAALP-PKPARPPAVSPALTQTPLLPQPPM 905
Query: 402 HQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-------FLPT-EAQAQVSPPPPYPAPQE 453
Q L P AP TS + QL LP+ + Q+Q PP P P
Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS 965
Query: 454 LTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSS-LTNFFPDVGFD------- 503
+ Q L QQP P P Q PQ P L P Q S+ + P G
Sbjct: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025
Query: 504 QQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYS--NCGSLPNTILPEDSSTSLFKDL 561
QQ P PA PQQV R H + PYS + P+ ++ S F+ L
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPR------HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
Score = 36.2 bits (82), Expect = 0.092
Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 7/123 (5%)
Query: 430 QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489
Q+ P Q PPP P P Q Q P P P+ QAA ++ S + Q
Sbjct: 745 QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ 804
Query: 490 GSSLTNFFPDVGFD------QQSMR-PGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCG 542
L P FD Q + P P P +P + S + H SP +
Sbjct: 805 VPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN 864
Query: 543 SLP 545
+LP
Sbjct: 865 ALP 867
Score = 35.0 bits (79), Expect = 0.20
Identities = 61/254 (24%), Positives = 88/254 (34%), Gaps = 41/254 (16%)
Query: 350 PQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLS---PGPEA---HQ 403
PQ + A ++ FS S S+ + S S + ++P + PG E H
Sbjct: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740
Query: 404 GFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYP--APQELTQPLLQQ 461
+Q+ AP P Q Q P Q Q PPPP P PQ+ +
Sbjct: 741 HHHQQMQQ----APAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSS 796
Query: 462 PR---APEAPAQQPQAASS--------------LPQSDFQLLPAQGSSLTNFFPDVGFDQ 504
P A + P +PQ S LPQ + LP +Q
Sbjct: 797 PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPE---LPPHLPQPPEHSTPPHLNQ 853
Query: 505 QSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSA 564
++ PA +P QQ SR + L P P + P + P + T L
Sbjct: 854 HAVVSPPALHNALP--QQPSRPSNRAAALPPKP-----ARPPAVSPALTQTPLLP--QPP 904
Query: 565 LAGLPEVSLNVDTP 578
+A P+V L + P
Sbjct: 905 MAQPPQVLLEDEEP 918
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 50.1 bits (118), Expect = 6e-06
Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 38/204 (18%)
Query: 310 PAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS- 368
P + + L S S S++ P++ AT + + L+ L + P+ SA PSL+
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-PPSLQTLPS 356
Query: 369 --LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ--LSSTSPLAPY 418
+ PS +TT+L P+ + PP+SPL +P P+A + + SP A
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPLQAPPSPPASP 415
Query: 419 PTSQMVSSDRS----------QLSFLPTEA---QAQVSPP----------PPYPAPQELT 455
P S + + Q F P + QA SPP PP AP L
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475
Query: 456 QPLLQQPRAPEAPAQQPQAASSLP 479
P LQ P P PA P + S+ P
Sbjct: 476 APPLQVP--PSPPASPPMSPSATP 497
Score = 43.5 bits (101), Expect = 6e-04
Identities = 63/230 (27%), Positives = 86/230 (37%), Gaps = 24/230 (10%)
Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362
G S P A H GLQ+ R Q T + + +L P +S P A+ P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALG--PLSSSPLATP-SP 309
Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQ 422
S L S + P+L T S S +PL L+P + + L S P +
Sbjct: 310 SAALQSQAPPTLPATPHS--SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 423 MVSSDRSQL--SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
+ S Q SFLP+ + ++ PPP AP L P LQ P +P A A+ PQ
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426
Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
+ L V Q P P+ P Q P S + S
Sbjct: 427 APNALA-------------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Score = 37.7 bits (86), Expect = 0.032
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 28/160 (17%)
Query: 353 SVPNASALHPSLRLFSLSNPSLSTTNLS-GPSRRRQPPVSPLTLSPGPEAHQGFSR---Q 408
S P + + PS S + PSL+ L PS PP+SP + +P P+A + Q
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQ 511
Query: 409 LSSTSPLAP---------------------YPTSQMVSSDRSQLSFLPTEAQAQVSPPPP 447
L+ P AP P S S S L+ P +A ++ P
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 571
Query: 448 YPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
P P LQ PR P P P + S P+ L P
Sbjct: 572 QVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAP 609
Score = 35.4 bits (80), Expect = 0.16
Identities = 56/199 (28%), Positives = 80/199 (40%), Gaps = 30/199 (15%)
Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363
AA T +G+ + S+R P + K+V S+S ++ + S P+A P+
Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGF-SRQLS------------ 410
R S S LS+ SGPS R P P P+ Q Q++
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 411 -STSPLA-PYPTSQMVSSDRSQLSFLP--TEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
S+SPLA P P++ + S L P + Q++ P P P P LQ P
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ--TLPS 356
Query: 467 APAQQP-QAASSLPQSDFQ 484
PA P QA +SL Q
Sbjct: 357 PPATPPSQATTSLGSPTLQ 375
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.7 bits (117), Expect = 8e-06
Identities = 61/238 (25%), Positives = 87/238 (36%), Gaps = 40/238 (16%)
Query: 321 SSGLQSSRSNPSIQATLNKTVLSSSLNNHPQ----TSVPNASALHPSLRLFSLSNPSLST 376
S L++ S P + L+ S L+ P+ + P AS L P +S P +
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 377 TNLSGPSRRRQ-PPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLP 435
P R PP LSP PE SPL+P P + +S P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEE-----------SPLSPPPEASRLSPPPEDSPMSP 637
Query: 436 TEAQAQVSPPP------PYPAPQELTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQ 484
++ +SPPP P P L+ P + P +P E+P P AS L P D
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697
Query: 485 LLPAQGSSLTNFFPD-----VGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSP 537
P S + P+ + ++ + P P PQ P + HL P P
Sbjct: 698 TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP--------RSEGPHLSPRP 747
Score = 49.3 bits (116), Expect = 1e-05
Identities = 81/282 (28%), Positives = 112/282 (39%), Gaps = 57/282 (20%)
Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
P ++A LN+ + P P S L P P S T+ + R PP
Sbjct: 428 PQLEAPLNEEM--------PLLPPPEESPLSPP--------PEESPTSPPPEASRLSPPP 471
Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPP---PP 447
L SP PEA SR L SPL+P P +S F P E ++ +SPP PP
Sbjct: 472 EELPASPLPEALH-LSRPLEE-SPLSPPPEESPLSPPPESSPFSPLE-ESPLSPPEESPP 528
Query: 448 YPA-------PQE---LTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQLLPAQGSS 492
PA P E L+ P + P +P E P P AS L P + + P S
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 493 LTNFFPDVG-----FDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNT 547
+ P+ F++ + P P++ PL ++ L P P + S P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPP---PEESPLSPP-----PEASRLSPPPEDSPMSPP-- 638
Query: 548 ILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEP 589
PE+S S ++ S L+ LP VS +P P E L P
Sbjct: 639 --PEESPMSPPPEV-SRLSPLPVVSRL--SPPPEESPLSPPP 675
Score = 42.7 bits (99), Expect = 0.001
Identities = 70/290 (24%), Positives = 103/290 (35%), Gaps = 24/290 (8%)
Query: 325 QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384
+S S P ++ L+ SS + ++ + PS L + +P + LS P
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
Query: 385 RR--QPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQV 442
PP L SP PEA + SP++P P +S P ++ +
Sbjct: 551 ESPLSPPPEELPTSPPPEASR--LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 443 SPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGF 502
SPPP PL P A + S P + + P S + P V
Sbjct: 609 SPPPE-------ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV-- 659
Query: 503 DQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLN 562
+ P P P + + ++ L P P + S P PEDS S
Sbjct: 660 -SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP----PEDSPAS--PPPE 712
Query: 563 SALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEE 612
+L LP L PL EE Q+ P S +G ++ L P EE
Sbjct: 713 DSLMSLP---LEESPLLPLPEEPQLCPRS-EGPHLSPRPEEPHLSPRPEE 758
Score = 35.0 bits (79), Expect = 0.20
Identities = 67/279 (24%), Positives = 94/279 (33%), Gaps = 33/279 (11%)
Query: 326 SSRSNPSIQATLNKTVLSSSLNNHPQTS----VPNASALHPSLRLFSLSNP-SLSTTNLS 380
S S P + ++ S ++ P+ S +P S L P LS P S T+
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683
Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSST-------SPLAPYPTSQMVS--SDRSQL 431
+ R PP SP PE S SPL P P + S+ L
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Query: 432 SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGS 491
S P E P P+ +PQ L QP P P+ PQ++ L Q
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP-CLCAVPEEPHLSPQAEGPHLSPQPE 802
Query: 492 SLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPE 551
L + P ++ + P P P P ++ HL P C + P
Sbjct: 803 EL-HLSPQT--EEPHLSPVPEEPCLSPQPEES--------HLSPQSEEPC------LSPR 845
Query: 552 DSSTSLFKDLNS-ALAGLPEVSLNVDTPFPLEEELQIEP 589
+ L +L L+ PE P EEL + P
Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
Score = 34.3 bits (77), Expect = 0.35
Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 15/142 (10%)
Query: 338 NKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSP 397
++T+LS Q ++ P L+ FS T L+G + P +
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKP-LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 398 GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-FLPTEAQAQVSPPPPYPAPQELTQ 456
GP HQG PLA T + ++++ ++ L ++Q + P P P P L
Sbjct: 4040 GPSTHQG--------GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ- 4090
Query: 457 PLLQQPRAPEAPAQQPQAASSL 478
LQ P P QQ Q S L
Sbjct: 4091 --LQPPL--RLPGQQQQQVSLL 4108
Score = 32.0 bits (71), Expect = 1.7
Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 409 LSSTSPLAPYPTSQ------MVSSDRSQLSFLPTEAQAQVSPPPPYPAPQEL---TQPLL 459
L SP AP P +Q + + D QLS P E + SPPP AP T+PL+
Sbjct: 4879 LKQESP-APEPPTQHSYTYNVSNLDVRQLSAPPPE---EPSPPPSPLAPSPASPPTEPLV 4934
Query: 460 QQPRAP--EAPAQQPQAASSLPQS 481
+ P P E P P +S P+S
Sbjct: 4935 ELPTEPLAEPPVPSPLPLASSPES 4958
Score = 31.6 bits (70), Expect = 2.3
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 35/175 (20%)
Query: 389 PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ-AQVSPPP- 446
PV P+ L P P + G SP+ P S Q S +P + +Q SPP
Sbjct: 995 PVPPMILPPSPGSPVG------PASPILMEPLPPQCSP-LLQHSLVPQNSPPSQCSPPAL 1047
Query: 447 --PYPAP-------------QELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQL---LPA 488
P+P EL + ++ PE PA +P A S LP L P+
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 489 QGSSLTNF-------FPDVGFDQQSMRPGPA-FPQQVPLVQQGSRELQDSFHLRP 535
+L +F P G D +P P P + +GS L D L P
Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162
Score = 31.2 bits (69), Expect = 3.0
Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 19/96 (19%)
Query: 380 SGPSRRRQP--PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQL----SF 433
+GP + P P P LS GP L P P P+S SQL S
Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPV--------LGPVHPTPP-PSSPQEPKRPSQLPSPSSQ 4329
Query: 434 LPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPA 469
LPTEAQ PP +P + P L+ P +PA
Sbjct: 4330 LPTEAQL----PPTHPGTPKPQGPTLEPPPGRVSPA 4361
Score = 30.0 bits (66), Expect = 6.6
Identities = 35/129 (27%), Positives = 47/129 (36%), Gaps = 18/129 (13%)
Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLA----------PYPTSQMVSSDRSQ 430
G R Q P L+P P +H R S T P A P P S RS
Sbjct: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS- 2402
Query: 431 LSFLPTEAQAQVSPPPPYPAPQELTQ-PLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489
LP++ ++V P P Q +Q PL +P + EA P + P++
Sbjct: 2403 ---LPSDPFSRV---PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
Query: 490 GSSLTNFFP 498
S F P
Sbjct: 2457 PQSRDPFAP 2465
>gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]
Length = 525
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/249 (26%), Positives = 93/249 (37%), Gaps = 31/249 (12%)
Query: 270 TGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRS 329
TG +LP + PLP G++ G +V P +T QSSR
Sbjct: 209 TGPTLPGGRESSEAYPLP--------QLGAIGSGQAVAYGPFVLT----------QSSRP 250
Query: 330 NPSIQATLNKTVLSSSL-NNHPQTSVPNAS--ALHPSLRLFSLSNPSLSTTNLSG----- 381
+ +L ++ S + ++ P T + P L SL P T L+
Sbjct: 251 TDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPRTPTPGLTEGGGTG 310
Query: 382 -PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
PS++R+ P SP T GP+ G + S + P P P S DR L +A
Sbjct: 311 LPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRA 366
Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500
+ PYPA EL P Q +P+ P + L PA S+L P
Sbjct: 367 PLGSALPYPARSELAPPGAQDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 426
Query: 501 GFDQQSMRP 509
F + RP
Sbjct: 427 QFTFRKRRP 435
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 48.9 bits (115), Expect = 1e-05
Identities = 68/255 (26%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402
S QT N + HP + S S T + PS ++QP P L S P
Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519
Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
Q S+ SP APYP+ Q + Q PPY PQ + QQP
Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565
Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522
+ P QAA PQS Q S T + QQ P PQ++
Sbjct: 566 QQPAPSTLSQQAAYPQPQS-------QQSQQT------AYSQQRFPP----PQELS---- 604
Query: 523 GSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 582
QDSF S S P+ + + L S + LP++S ++D P+
Sbjct: 605 -----QDSFG------SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID-DLPMG 652
Query: 583 EELQIEP-LSLDGLN 596
E + P +S G++
Sbjct: 653 TEGALSPGVSTSGIS 667
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 32/178 (17%)
Query: 372 PSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSS--TSPLAPYPTSQMVSSDRS 429
PS + + PSR P + H + Q S+ T +P+P+ Q +
Sbjct: 1311 PSNPDSGMYSPSR-----YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365
Query: 430 QLSFLPTEAQAQVSPPPP------YPAPQELTQPLLQQPRAPEA---PAQQPQAASSLPQ 480
Q ++ PP Y P Q QQ + P A PA Q QAA PQ
Sbjct: 1366 QQNY-KRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424
Query: 481 SDF-----QLLPAQGSSLT---------NFFP-DVGFDQQSMRPGPAFPQQVPLVQQG 523
D PA ++ T N FP G D+ S PG Q +P G
Sbjct: 1425 QDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 48.9 bits (115), Expect = 1e-05
Identities = 68/255 (26%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402
S QT N + HP + S S T + PS ++QP P L S P
Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519
Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
Q S+ SP APYP+ Q + Q PPY PQ + QQP
Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565
Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522
+ P QAA PQS Q S T + QQ P PQ++
Sbjct: 566 QQPAPSTLSQQAAYPQPQS-------QQSQQT------AYSQQRFPP----PQELS---- 604
Query: 523 GSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 582
QDSF S S P+ + + L S + LP++S ++D P+
Sbjct: 605 -----QDSFG------SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID-DLPMG 652
Query: 583 EELQIEP-LSLDGLN 596
E + P +S G++
Sbjct: 653 TEGALSPGVSTSGIS 667
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 48.5 bits (114), Expect = 2e-05
Identities = 44/161 (27%), Positives = 60/161 (37%), Gaps = 11/161 (6%)
Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
GPS +P + P + P QG Q P P V+ L+ P
Sbjct: 1975 GPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLG 2034
Query: 441 QV--SPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL---PQSDFQLLPAQGSSLTN 495
QV SP P Q+ Q LL+ R+P +P QQ Q S L PQ + + + N
Sbjct: 2035 QVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN 2094
Query: 496 FFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPS 536
P Q + P PQ P +Q + Q H P+
Sbjct: 2095 SNP------QPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA 2129
Score = 42.7 bits (99), Expect = 0.001
Identities = 79/297 (26%), Positives = 108/297 (36%), Gaps = 53/297 (17%)
Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
S G +V NIP A SS P QA ++ SSS + P +
Sbjct: 772 SQGMNVTNIPLA------------PSSGQAPVSQAQMS----SSSCPVNSPIMPPGSQGS 815
Query: 361 HPSLRLFSLSNPSLSTTNLSG-PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYP 419
H + L P+L + S PSR P +P ++ ++Q +T+ AP P
Sbjct: 816 H--IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIG---------AQQPPATTIPAPVP 864
Query: 420 TSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQ--PRAPEAP-AQQPQ--- 473
T +P Q+Q PPP P T L QQ P P AP A QPQ
Sbjct: 865 TPPA----------MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQP 914
Query: 474 -----AASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQ 528
A+S+P LLP Q ++ + P V + Q P +V Q E Q
Sbjct: 915 RSQQSTAASVPTPTAPLLPPQPATPLS-QPAVSIEGQVSNPPSTSSTEVN--SQAIAEKQ 971
Query: 529 DSFHLRPSPYSNCGS-LPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEE 584
S ++ P PED S S +D E S + T EE+
Sbjct: 972 PSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028
Score = 34.3 bits (77), Expect = 0.35
Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 11/81 (13%)
Query: 400 EAHQGFSRQLSSTSPLAPYPTS-------QMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452
+A+Q Q SP+ P P S S Q +P QV P P P+P+
Sbjct: 2258 QAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPR 2317
Query: 453 ELTQPLLQQPRAPEAPAQQPQ 473
+QP P + +P QPQ
Sbjct: 2318 PQSQP----PHSSPSPRMQPQ 2334
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 48.1 bits (113), Expect = 2e-05
Identities = 105/436 (24%), Positives = 159/436 (36%), Gaps = 50/436 (11%)
Query: 190 PYMGFCDGENNGHGEVASFPGPLKEENLLNVPKP-------LPKQLWETKEIQSLSGRPR 242
P F G+ N H F G L + ++ V + L KQ + QS G
Sbjct: 193 PGGSFLFGKMNPHA--VQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLF 250
Query: 243 SCDVGGGNAFPHNGQNLGL------SPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHH 296
S D G F + LGL +P LG+L G P T + P T+ H
Sbjct: 251 SQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRG-PRGTVAPATPTKPQRTSPTNPH 309
Query: 297 FGSMSVGN-----------SVNNIPAAMTHLGIRSSSGL-QSSRSNPSIQATLNKTVLSS 344
M+VG S +N M + S+ + + + PS + T K S
Sbjct: 310 -QHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSL 368
Query: 345 SLN-NHPQTSVPNASALHPSLRLF--SLSNPSLST------TNLSGPSRRRQPPVSPLTL 395
+ P TS+ + HP+ + S + +L T T+ P+R +P P+
Sbjct: 369 PTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQR 428
Query: 396 SPG-PEAHQGFSRQLSST--SPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452
+PG P +R L T S P PT + + + P A+ PPP+ A
Sbjct: 429 NPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALS 488
Query: 453 ELTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510
P R+ PA P + +S P++ +P GS+ T +G + S + G
Sbjct: 489 SSPAPTPGSTRSTRPPATMVPPTSGTSTPRT-APAVPTPGSAPTGSKKPIG-SEASKKAG 546
Query: 511 PAFPQQVPLVQQGSRELQD----SFHLRPSPYSNCGSLPNT-ILPEDSSTSLFKDLNSAL 565
P + P+ + + +D RPSP S T L + L
Sbjct: 547 PKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTS 606
Query: 566 AGLPEVSLNVDTPFPL 581
+G L TPFPL
Sbjct: 607 SGYSIFHLAGSTPFPL 622
>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 2 [Homo sapiens]
Length = 1990
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/210 (24%), Positives = 87/210 (41%), Gaps = 19/210 (9%)
Query: 319 RSSSGLQSSRSNPSIQATLNKTVLSSS-LNNHPQTSVPNASAL-HPSLRLFSLSNPSLST 376
R S GL +S PS + +SSS L +H ++S++ P+ + + ++P+LS
Sbjct: 1432 RPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSP 1491
Query: 377 TNLSGPSRRRQPPVSPL------TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQ 430
T+ + R P SP SP P QG SPL P + S
Sbjct: 1492 THQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESM 1551
Query: 431 LSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAP-----EAPAQQPQAASSLPQSDFQL 485
+ ++Q P Y ++Q L +P++P + P Q PQ ++PQ +L
Sbjct: 1552 SVY-----RSQSGSPVRYQQETSVSQ-LPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRL 1605
Query: 486 LPAQGSSLTNFFPDVGFDQQSMRPGPAFPQ 515
PA+ + + P ++ P A+ Q
Sbjct: 1606 QPAKAQIVRSNQPSPAVHSSTVIPTGAYGQ 1635
Score = 32.3 bits (72), Expect = 1.3
Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 15/183 (8%)
Query: 305 SVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNK--TVLSSSLNNHPQTSVPNASALHP 362
S + P + L + SS S +P + + + +V + + HP T P +
Sbjct: 1722 SASYYPVCHSKLDLERSS---SQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSV 1778
Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAP----Y 418
LR SN ST+NL+ P+ R + + + P + R SP++P Y
Sbjct: 1779 GLRFSPSSNSISSTSNLT-PTFRPSSSIQQMEIPLKP----AYERSCDELSPVSPTQGGY 1833
Query: 419 PTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL 478
P+ S + + A+ Q P + + + +P +P PQ S
Sbjct: 1834 PSEPTRSRTTPFMGIIDKTARTQ-QYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFS 1892
Query: 479 PQS 481
P S
Sbjct: 1893 PPS 1895
>gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo
sapiens]
Length = 488
Score = 46.6 bits (109), Expect = 7e-05
Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 12/162 (7%)
Query: 355 PNASALHPSLRLFSLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSS 411
PN L P SL P+ T G PS++R+ P SP T GP+ G + S
Sbjct: 257 PNVHRLPPPP---SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASL 309
Query: 412 TSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQ 471
+ P P P S DR L + + PYPA EL P + +P+
Sbjct: 310 SGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPC 369
Query: 472 PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMR--PGP 511
P + L PA S+L P F + +R PGP
Sbjct: 370 PGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 411
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 46.6 bits (109), Expect = 7e-05
Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%)
Query: 11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66
N + SE+I+ + ++EET A ++ T+ L R Q L L R G S P ++
Sbjct: 68 NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
Query: 67 SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124
Q S S PS + +V GL + P+R P H P
Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167
Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181
S QP D S PRQ P E HP T S + + P P Y G
Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241
G P MG G G +S GP + + P P + + + +P
Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275
Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
+ VGGGN FPH NL P L LN + P + PLP L +
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332
Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341
H G ++ S +++P A + SS S+ S A+ + +
Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400
SSS + P + ++P+ P S+SN P + QP +
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433
Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460
S+ + S P P P +++++ + P AQ + PP Q Q
Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488
Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516
Q + + QQ Q S P P +G S + P + S+RP P P
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548
Query: 517 VP 518
+P
Sbjct: 549 LP 550
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 46.6 bits (109), Expect = 7e-05
Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%)
Query: 11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66
N + SE+I+ + ++EET A ++ T+ L R Q L L R G S P ++
Sbjct: 68 NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
Query: 67 SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124
Q S S PS + +V GL + P+R P H P
Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167
Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181
S QP D S PRQ P E HP T S + + P P Y G
Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222
Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241
G P MG G G +S GP + + P P + + + +P
Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275
Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
+ VGGGN FPH NL P L LN + P + PLP L +
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332
Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341
H G ++ S +++P A + SS S+ S A+ + +
Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400
SSS + P + ++P+ P S+SN P + QP +
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433
Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460
S+ + S P P P +++++ + P AQ + PP Q Q
Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488
Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516
Q + + QQ Q S P P +G S + P + S+RP P P
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548
Query: 517 VP 518
+P
Sbjct: 549 LP 550
>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
sapiens]
Length = 800
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 9/149 (6%)
Query: 368 SLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMV 424
SL P+ T G PS++R+ P SP T GP+ G + S + P P P
Sbjct: 395 SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPP 450
Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQ 484
S DR L + + PYPA EL P + +P+ P +
Sbjct: 451 SRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGL 510
Query: 485 LLPAQGSSLTNFFPDVGFDQQSMR--PGP 511
L PA S+L P F + +R PGP
Sbjct: 511 LSPAPRSALGETAPTAQFTFRKVRNPPGP 539
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/194 (27%), Positives = 74/194 (38%), Gaps = 21/194 (10%)
Query: 308 NIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLF 367
NIP A H ++ S QS S+ A N+ V L N T+V A S +
Sbjct: 688 NIPIAPIHSSAQAMSPTQSIGLVQSLLA--NQNVQLDVLTNQT-TAVGTAEHAGDSATQY 744
Query: 368 SLSNPSLSTTNLSGPSRR-----RQPPVSPLTLSPGPEA--------HQGFSRQLSSTSP 414
+SN + + S + PP PL+L P P+ H + S
Sbjct: 745 PVSNRYSNPGQVIFGSVEMGRIIQNPP--PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSA 802
Query: 415 LAPYPTSQMVSSDRSQLSFLPTEAQA-QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQ 473
A PT Q+ + + + P E Q +++PPPPYP P P P QP
Sbjct: 803 KALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPP--PPLPPPQPP 860
Query: 474 AASSLPQSDFQLLP 487
L + DF L P
Sbjct: 861 VDVCLKKGDFSLYP 874
>gi|236459851 ubinuclein 2 [Homo sapiens]
Length = 1347
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 15/185 (8%)
Query: 275 PDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNN----IPAAMTHLGIRSSSGLQSSRSN 330
P + L STP P + H S +V ++ + A ++ + + S ++
Sbjct: 977 PLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAAS 1036
Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
P + A+ L + ++ P PSL + PS+ST +S + +P V
Sbjct: 1037 PKLAASPKPATSPKPLPSPKPSASPK-----PSLS----AKPSVSTKLISKSNPTPKPTV 1087
Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450
SP + SP QG S+ SP+ P+ +S L+ LP+ + + P A
Sbjct: 1088 SPSSSSPNALVAQG--SHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQA 1145
Query: 451 PQELT 455
P +LT
Sbjct: 1146 PSKLT 1150
Score = 32.3 bits (72), Expect = 1.3
Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 8/161 (4%)
Query: 428 RSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
R + + E + + PP PQ +P +P AP PA + A P S + LP
Sbjct: 17 RREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQ---PPSREKPLP 73
Query: 488 AQGSSLTNFFPDVGFDQQSMRPGPAFP-QQVPLVQQGSRELQDSFHLRPSPYSNCGSLPN 546
+ S P + ++ RP P P +PL RE P P L
Sbjct: 74 QREVSRAE--PPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRETVRLEL 131
Query: 547 TIL-PEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQ 586
+ P D S F L G L + T P +E Q
Sbjct: 132 VLKDPTDESCVEFSYPELLLCGEQRKKL-IHTEDPFNDEHQ 171
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 45.1 bits (105), Expect = 2e-04
Identities = 58/290 (20%), Positives = 97/290 (33%), Gaps = 31/290 (10%)
Query: 325 QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384
Q S++ PS+ T+ + + P+ A+A F + T +L P
Sbjct: 1110 QPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKA 1169
Query: 385 RRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSP 444
+R P +P + + S + ++ P P + + + +E + Q +P
Sbjct: 1170 QRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP 1229
Query: 445 PPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQ 504
P P P P+ T P P P + + ++ P++ P+ S P G +
Sbjct: 1230 PAPPPLPETWTPTARSSPPLP--PPAEERTSAKGPETMASKFPSSSSDWR--VPGQGLEN 1285
Query: 505 QSMRPGPAFPQQVPLVQQGSRELQDS-------------------FHLRPSPYSNC-GSL 544
+ P P P P V G S +RP P S+
Sbjct: 1286 RGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSV 1345
Query: 545 PNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDG 594
N +L E D A LPE P P + L P ++ G
Sbjct: 1346 DNRVLSE-------VDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILG 1388
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 44.7 bits (104), Expect = 3e-04
Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 27/243 (11%)
Query: 348 NHPQTSVPNASALHPSLRLFSLSNPSLSTT-NLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406
+HP S P+ S + P S P +S +L P R P VSPL LS P
Sbjct: 68 HHPLMS-PHYSLVSPQYSPVSPHCPLVSPHYSLVSPHR---PLVSPL-LSGVPSPPSDVP 122
Query: 407 RQLSSTSPLA------PYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460
LS L P ++S S LS +P+ SPP P+P LL
Sbjct: 123 SLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLS 182
Query: 461 QPRAPEAPAQQPQAASSLPQSDFQLL-----PAQGSSLTNFFPDVGFDQQSMRPGPAFPQ 515
+P + P + P SD LL P L + P D P+ P
Sbjct: 183 GVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDV------PSLPS 236
Query: 516 QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNV 575
VP + D PS S S P+ I P SL D+ S + +P + V
Sbjct: 237 DVPSLSGVPSPPSDV----PSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGV 292
Query: 576 DTP 578
+P
Sbjct: 293 PSP 295
Score = 40.0 bits (92), Expect = 0.006
Identities = 62/237 (26%), Positives = 89/237 (37%), Gaps = 29/237 (12%)
Query: 350 PQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQL 409
P + VP+ + PSL S PS + LSG P P +SP + L
Sbjct: 227 PPSDVPSLPSDVPSLSGVP-SPPSDVPSLLSGV------PSPPSDISPPSDVPS-----L 274
Query: 410 SSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPA 469
S P P ++S S S +P+ SPP P+P PLL +P +
Sbjct: 275 LSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPS-DIPLLSGVPSPPSDV 333
Query: 470 QQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQD 529
P + P SD LL S L+ D + P+ P VP + L
Sbjct: 334 PSPPSDVPSPPSDVPLLSGVPSPLS--------DVPLLSGVPSPPSDVPSLLMSPHRLLM 385
Query: 530 SFHLRPSPY-----SNCGSLPNTILPEDSSTSLFKDLNSA---LAGLPEVSLNVDTP 578
S + SP+ S +P+ + SS S L S L+G+P + V +P
Sbjct: 386 SHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPSP 442
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 43.9 bits (102), Expect = 4e-04
Identities = 55/213 (25%), Positives = 77/213 (36%), Gaps = 26/213 (12%)
Query: 284 TPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLS 343
TP P S TT SV N + +P A S+S Q P+ +AT + S
Sbjct: 1343 TPKPTSR-TTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPVTPEPTSRATRGRKNRS 1399
Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQ 403
S P+T VP A L PS P ++ G + R + PE
Sbjct: 1400 SGKT--PETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPE--- 1454
Query: 404 GFSRQLSSTSPLAPYPTSQMV--SSDRSQL----SFLPTEAQAQVSPPPPYPAPQELTQP 457
S+ P+ P PTSQ +DRS + + +PT + Q S P E T
Sbjct: 1455 -LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSR 1513
Query: 458 LLQ-----------QPRAPEAPAQQPQAASSLP 479
+ + P AP QP ++ P
Sbjct: 1514 TTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1546
Score = 38.1 bits (87), Expect = 0.024
Identities = 41/169 (24%), Positives = 64/169 (37%), Gaps = 10/169 (5%)
Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
S+S Q P+ QAT +T SS P+T VP A L PS P ++
Sbjct: 1417 STSTDQPVTPEPTSQATRGRTNRSSVKT--PETVVPTAPELQPSTSTDQPVTPEPTSQAT 1474
Query: 380 SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439
G + R + PE S+ P+ PTS+ +++ S E
Sbjct: 1475 RGRTDRSSVKTPETVVPTAPE----LQASASTDQPVTSEPTSRTTRGRKNRSSVKTPET- 1529
Query: 440 AQVSPPPPYPAPQELT-QPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
V P P P T QP+ +P + + +++ P+S + P
Sbjct: 1530 --VVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576
Score = 37.7 bits (86), Expect = 0.032
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
S+S Q S P+ QAT + SS P+ VP A L PS P T+
Sbjct: 1253 STSTDQPVTSEPTYQATRGRKNRSSVKT--PEPVVPTAPELRPSTSTDRPVTPK--PTSR 1308
Query: 380 SGPSRRRQPPV-SPLTLSP-GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTE 437
+ SR V +P T+ P PE S+ P+ P PTS+ S + S E
Sbjct: 1309 TTRSRTNMSSVKTPETVVPTAPE----LQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPE 1364
Query: 438 AQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQS 481
+ ++P P E QP+ +P + ++ +++ P++
Sbjct: 1365 STVPIAPELPPSTSTE--QPVTPEPTSRATRGRKNRSSGKTPET 1406
Score = 31.2 bits (69), Expect = 3.0
Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 23/152 (15%)
Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
PSI+ T+ KT S HP P + T S R P
Sbjct: 1072 PSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPK--------PKIRTRKSS-----RMTPF 1118
Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450
P T S PE H S+ P+ P PTSQ + RS+ + + V P P
Sbjct: 1119 -PAT-SAAPEPHPS----TSTAQPVTPKPTSQ---ATRSRTNRSSVKTPEPVVPTAPELQ 1169
Query: 451 PQELT-QPLLQQPRAPEAPAQQPQAASSLPQS 481
P T QP+ +P + ++ +++ P++
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPET 1201
Score = 29.6 bits (65), Expect = 8.6
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 7/130 (5%)
Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
S+S Q S P+ + T + SS P+T VP A L PS P ++
Sbjct: 1499 SASTDQPVTSEPTSRTTRGRKNRSSVKT--PETVVPAAPELQPSTSTDQPVTPEPTSRAT 1556
Query: 380 SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439
G + R + PE SR T P PTS+ + R+ S + T
Sbjct: 1557 RGRTNRSSVKTPESIVPIAPELQPSTSRNQLVT----PEPTSR-ATRCRTNRSSVKTPEP 1611
Query: 440 AQVSPPPPYP 449
+ P P+P
Sbjct: 1612 VVPTAPEPHP 1621
>gi|54792138 helicase with zinc finger domain [Homo sapiens]
Length = 1942
Score = 43.9 bits (102), Expect = 4e-04
Identities = 63/290 (21%), Positives = 97/290 (33%), Gaps = 49/290 (16%)
Query: 287 PASLDTTDHHFGSMSV-------GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNK 339
P+ + D H G+ + GN V ++P + G + + N
Sbjct: 1178 PSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNM 1237
Query: 340 TVLSS---------SLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGP--SRRRQP 388
+L + L +HP ++ H + S TN SGP ++ R P
Sbjct: 1238 NLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTP 1297
Query: 389 PVSP-----LTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVS 443
P + L P+ SR S P +P ++ L AQ +
Sbjct: 1298 EKKPTEPKQVDLESNPQNRSPESRP-SVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIP 1356
Query: 444 ----------PPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQL------LP 487
P PP+P PQ+ T QQ PE P Q P + + Q QL P
Sbjct: 1357 NRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPP 1416
Query: 488 AQGSSLTNFFPDVGFDQQSMRPGPAFP---------QQVPLVQQGSRELQ 528
Q S P+ F ++ P P Q P++Q+G L+
Sbjct: 1417 PQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLR 1466
Score = 32.0 bits (71), Expect = 1.7
Identities = 38/173 (21%), Positives = 57/173 (32%), Gaps = 12/173 (6%)
Query: 310 PAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNN----------HPQTSVPNASA 359
P + + S+ +S S PS+ K +LN H Q ++PN
Sbjct: 1301 PTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRH- 1359
Query: 360 LHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYP 419
HP +L P L + P P + P P QL+ P
Sbjct: 1360 FHPLPQLPRPPFPIPQQHTLLNQQQNNLPE-QPNQIPPQPNQVVQQQSQLNQQPQQPPPQ 1418
Query: 420 TSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQP 472
S + + F A SPP P++ P+LQ+ +P QP
Sbjct: 1419 LSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQP 1471
>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo
sapiens]
Length = 1268
Score = 43.9 bits (102), Expect = 4e-04
Identities = 72/290 (24%), Positives = 110/290 (37%), Gaps = 48/290 (16%)
Query: 273 SLPDLTNLHYSTP-LPASLDTT-DHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSN 330
SL + L +S+P LP++ D +H GS++V N+ I A + L +Q +S+
Sbjct: 253 SLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADS-LSCPVMQNVQPPKSS 311
Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPS--LSTTNLS-GPSRRRQ 387
P + L+ + SSS P +A HP + S++ PS L + G Q
Sbjct: 312 PVVSTVLSGSSGSSSTRTPP-------TANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQ 364
Query: 388 PPVSPLTLSPGP-------EAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
+P LS E + S+TS +P P S D + P +
Sbjct: 365 ASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSY----DALEGGSYPDMLSS 420
Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500
S P P PAP+ P + APA P A +PQ P
Sbjct: 421 SASSPAPDPAPE-------PDPASAPAPASAP--APVVPQPSKMAKP------------F 459
Query: 501 GFDQQSMRPGPAFPQQVPLVQ--QGSRELQDSFHLRPSPYSNCGSLPNTI 548
G+ +++PG PL+ Q S + F P Y L ++I
Sbjct: 460 GYGYPTLQPGYQ-NATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSI 508
>gi|33186895 selenoprotein V [Homo sapiens]
Length = 346
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/207 (26%), Positives = 81/207 (39%), Gaps = 19/207 (9%)
Query: 346 LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR-RRQPPVSPLT--LSPGPEAH 402
+NN +T P+++ S+R S P+ + T L P+ R + P+ LT L+P P
Sbjct: 1 MNNQARTPAPSSARTSTSVRA---STPTRTPTPLRTPTPVRTRTPIRTLTPVLTPSPA-- 55
Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
G S + + +P A PT + +P A A + P P P P P+
Sbjct: 56 -GTSPLVLTPAP-AQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPVPVRNPTPVPTPA 113
Query: 463 RAPEAPAQQP-QAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQ 521
R P + P A + L LP S L P + P P ++PL+
Sbjct: 114 RTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALP--------LDPPPEPAPELPLLP 165
Query: 522 QGSRELQDSFHLRPSPYSNCGSLPNTI 548
+ E S L PS S G P +
Sbjct: 166 EEDPEPAPSLKLIPSVSSEAGPAPGPL 192
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 43.5 bits (101), Expect = 6e-04
Identities = 67/275 (24%), Positives = 100/275 (36%), Gaps = 22/275 (8%)
Query: 350 PQTSVPNASA-LHPSLRLFSLSNPSLSTTNLSGP--SRRRQPPVSPLTLSPGPEAHQGFS 406
PQ P++S+ L S ++P S T GP S +P +P + +PGP + Q
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP-SRTPGPPSAQSSP 1080
Query: 407 RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
+PL +Q + R P + +PP P P +QP Q A
Sbjct: 1081 IDAQPATPLPQKDPAQPLEPKRPPPP-RPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139
Query: 467 APAQQPQAASSLP--------------QSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPA 512
PA A ++P S +L P S + F + ++P A
Sbjct: 1140 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1199
Query: 513 FPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPED--SSTSLFKDLNSALAGLPE 570
FP Q L R LQ+ +P G PN P + L S + P+
Sbjct: 1200 FPPQSSLPPPAQR-LQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258
Query: 571 VSLNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGL 605
V N + E L+I+P N+L+ S L
Sbjct: 1259 VKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQL 1293
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,235,924
Number of Sequences: 37866
Number of extensions: 1690182
Number of successful extensions: 10175
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 770
Number of HSP's that attempted gapping in prelim test: 7445
Number of HSP's gapped (non-prelim): 2401
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.