BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo sapiens] (618 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110431352 transducer of regulated CREB protein 3 isoform b [H... 1253 0.0 gi|110431354 transducer of regulated CREB protein 3 isoform a [H... 1248 0.0 gi|32171215 CREB regulated transcription coactivator 2 [Homo sap... 337 3e-92 gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 283 3e-76 gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 278 1e-74 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 7e-07 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 2e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 51 3e-06 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 6e-06 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 50 8e-06 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 50 8e-06 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 50 8e-06 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 50 8e-06 gi|105990535 coagulation factor V precursor [Homo sapiens] 49 1e-05 gi|239756297 PREDICTED: hypothetical protein [Homo sapiens] 49 1e-05 gi|50345997 E1A binding protein p300 [Homo sapiens] 49 2e-05 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 49 2e-05 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 47 4e-05 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 47 4e-05 gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled... 47 4e-05 gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ... 47 7e-05 gi|55750053 atrophin-1 [Homo sapiens] 47 7e-05 gi|55750041 atrophin-1 [Homo sapiens] 47 7e-05 gi|236459851 ubinuclein 2 [Homo sapiens] 46 1e-04 gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ... 46 1e-04 gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 45 2e-04 gi|33186895 selenoprotein V [Homo sapiens] 45 3e-04 gi|112421108 capicua homolog [Homo sapiens] 44 3e-04 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 44 4e-04 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 44 4e-04 >gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo sapiens] Length = 618 Score = 1253 bits (3241), Expect = 0.0 Identities = 618/618 (100%), Positives = 618/618 (100%) Query: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG Sbjct: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60 Query: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG Sbjct: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120 Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180 Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240 Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300 Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420 Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480 Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540 Query: 541 CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS 600 CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS Sbjct: 541 CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS 600 Query: 601 SMGLLDPSVEETFRADRL 618 SMGLLDPSVEETFRADRL Sbjct: 601 SMGLLDPSVEETFRADRL 618 >gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo sapiens] Length = 619 Score = 1248 bits (3229), Expect = 0.0 Identities = 618/619 (99%), Positives = 618/619 (99%), Gaps = 1/619 (0%) Query: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG Sbjct: 1 MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60 Query: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG Sbjct: 61 GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120 Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180 Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240 Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300 Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420 Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480 Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540 Query: 541 CGSLPNTILP-DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 599 CGSLPNTILP DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD Sbjct: 541 CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 600 Query: 600 SSMGLLDPSVEETFRADRL 618 SSMGLLDPSVEETFRADRL Sbjct: 601 SSMGLLDPSVEETFRADRL 619 >gi|32171215 CREB regulated transcription coactivator 2 [Homo sapiens] Length = 693 Score = 337 bits (863), Expect = 3e-92 Identities = 271/710 (38%), Positives = 353/710 (49%), Gaps = 116/710 (16%) Query: 2 AASPGSGSA---NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQ-QLRLTQ 57 A PGS +A NPRKFSEKIAL QRQAEET AFE++M D+ +R+Q QKL+ + Sbjct: 6 ANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSS 65 Query: 58 YHGGSLPNVSQLRSSASEFQPSFHQA-DNVRGTRHHGLVERPSRN---RFHPLHRRSGDK 113 ++GGSLPNV+Q+ S +EFQ H D+ R TRHHGLVER R+ PL R + Sbjct: 66 HYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT--- 122 Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKD---EKHPGFRLTSALNRTNSDSALHTSA 170 R D S + Y S P + SW R+ W + EK FRL SALNRT+SDSALHTS Sbjct: 123 --RHIDSSPYSPAYLSPPPESSW-RRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV 179 Query: 171 LSTKPQDPYGGGGQ-SAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLW 229 ++ PQD Y G S P+ G DGE + P EENLL+ K L K W Sbjct: 180 MNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV-------PAIEENLLD-DKHLLKP-W 230 Query: 230 ETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPAS 289 + K++ S S RPRSC+V G N FP Q + +NTGGSLPDLTNLH+ PLP Sbjct: 231 DAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP 290 Query: 290 LDTTDHHFGSMSVGNSVNNIPAAMTHLGIR---------SSSGLQSSRSNPSIQATLNKT 340 LD + + S+S GNS +N+ MTHLGI + GL S S+PS+Q++L+ Sbjct: 291 LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP 350 Query: 341 VLSSSLN--------NHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPS--------- 383 L +SL+ +H S+P +S L SL +PSLS LS S Sbjct: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410 Query: 384 ---------------RRRQPPVSPLTLSPGP----EAHQGFSRQLSSTSPLAPYPTSQMV 424 R+ P+SPL+L GP + Q +Q S T +Q V Sbjct: 411 LGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGV 470 Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAP------QELTQPLLQQPRAPE------------ 466 D S+LS Q PP PY +P Q T LQQP P Sbjct: 471 PLDTSKLS------TDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524 Query: 467 -------------APAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAF 513 P+ Q + P SDF L + S+ + + D GP F Sbjct: 525 PGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGF 584 Query: 514 -PQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILP-DSSTSLFKDLNSALAGLP--E 569 + P+ G ++ H + S GS PN IL DSS K++ +ALAG+P E Sbjct: 585 LGGEGPM--GGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFE 642 Query: 570 VS-LNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618 VS ++ LE+EL++EPL L+GLNMLSD L DP+VEE+FR+DRL Sbjct: 643 VSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692 >gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [Homo sapiens] Length = 634 Score = 283 bits (724), Expect = 3e-76 Identities = 239/681 (35%), Positives = 318/681 (46%), Gaps = 121/681 (17%) Query: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61 S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG Sbjct: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63 Query: 62 SLPNVSQLRSSASE--FQPSFHQA--DNVRGTRHHGLVERP--SRNRFHPLHRR--SGDK 113 SLPNV+Q+ S + FQ F + D R TRHHGLV+R R R HRR S DK Sbjct: 64 SLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDK 123 Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALST 173 GRQ D +G Y S P D SW RTNSDSALH S ++ Sbjct: 124 HGRQADSCPYGTMYLSPPADTSW---------------------RRTNSDSALHQSTMTP 162 Query: 174 KPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKE 233 + + G Q + + + PG EE K L KQ W+TK+ Sbjct: 163 TQPESFSSGSQDVHQKRVL------------LLTVPG--MEETTSEADKNLSKQAWDTKK 208 Query: 234 IQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293 S RP+SC+V G N FP Q + T NTGGSLPDLTN+H+ +PLP LD Sbjct: 209 TGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPE 265 Query: 294 DHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQT 352 + F ++S +S N+ A +THLGI + G+ + S+P + LS S Q Sbjct: 266 EPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRPAGVSPLSLSTEARRQQ 324 Query: 353 SVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQL 409 + P S L P + ++ SL + +QPP P P P A Sbjct: 325 ASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPA-------- 376 Query: 410 SSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAPQELTQPLLQQPRAP-- 465 S P P P + + L LP+ + + PPP P L Q + P P Sbjct: 377 SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSM 434 Query: 466 -----EAPAQQ---PQAASSLPQSDFQLLPAQG----------SSLTNFFPDVGFDQQ-S 506 APA Q A S QS + QG S+L + F D ++QQ + Sbjct: 435 GIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMA 494 Query: 507 MRPGPAFPQQV-------------PLVQQGSR----------------ELQDSFHLRPSP 537 R A Q+ L GS L DS L + Sbjct: 495 ARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYAS 554 Query: 538 YSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNML 597 +S ++ T+ +S SL K+L S+LAG+ +VS + D+ FPL +EL+I+PL+LDGL+ML Sbjct: 555 HSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL-DELKIDPLTLDGLHML 613 Query: 598 SDSSMGLLDPSVEETFRADRL 618 +D M L DP+ E+TFR DRL Sbjct: 614 NDPDMVLADPATEDTFRMDRL 634 >gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [Homo sapiens] Length = 650 Score = 278 bits (710), Expect = 1e-74 Identities = 241/697 (34%), Positives = 320/697 (45%), Gaps = 137/697 (19%) Query: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61 S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG Sbjct: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63 Query: 62 SLPNVSQLRSSASE--FQPS----------------FHQA--DNVRGTRHHGLVERP--S 99 SLPNV+Q+ S + FQPS F + D R TRHHGLV+R Sbjct: 64 SLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRE 123 Query: 100 RNRFHPLHRR--SGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSAL 157 R R HRR S DK GRQ D +G Y S P D SW Sbjct: 124 RGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSW--------------------- 162 Query: 158 NRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENL 217 RTNSDSALH S ++ + + G Q + + + PG EE Sbjct: 163 RRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVL------------LLTVPG--MEETT 208 Query: 218 LNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDL 277 K L KQ W+TK+ S RP+SC+V G N FP Q + T NTGGSLPDL Sbjct: 209 SEADKNLSKQAWDTKKTGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDL 265 Query: 278 TNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQAT 336 TN+H+ +PLP LD + F ++S +S N+ A +THLGI + G+ + S+P Sbjct: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRP 324 Query: 337 LNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPL 393 + LS S Q + P S L P + ++ SL + +QPP P Sbjct: 325 AGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQ 384 Query: 394 TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAP 451 P P A S P P P + + L LP+ + + PPP P Sbjct: 385 PPPPPPPA--------SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVP 434 Query: 452 QELTQPLLQQPRAP-------EAPAQQ---PQAASSLPQSDFQLLPAQG----------S 491 L Q + P P APA Q A S QS + QG S Sbjct: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494 Query: 492 SLTNFFPDVGFDQQ-SMRPGPAFPQQV-------------PLVQQGSR------------ 525 +L + F D ++QQ + R A Q+ L GS Sbjct: 495 TLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT 554 Query: 526 ----ELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 581 L DS L + +S ++ T+ +S SL K+L S+LAG+ +VS + D+ FPL Sbjct: 555 GSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL- 613 Query: 582 EELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618 +EL+I+PL+LDGL+ML+D M L DP+ E+TFR DRL Sbjct: 614 DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 53.1 bits (126), Expect = 7e-07 Identities = 50/176 (28%), Positives = 74/176 (42%), Gaps = 13/176 (7%) Query: 329 SNPSIQATLNKTV--LSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRR 386 ++P +Q +L+ V LSS L HP ++ + ++ P L SL P L T + P + Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524 Query: 387 QPPVSPLTLSP-------GPEAHQGFSRQLSSTS-PLAPYPTSQMVSSDRSQLSFLPTEA 438 PP S LT P P Q S L++ P P + + S L+ P E Sbjct: 525 TPPAS-LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583 Query: 439 QAQVSPPPPYPAPQELTQPLLQQPRAPEAP--AQQPQAASSLPQSDFQLLPAQGSS 492 + ++ PPP P + PL P P +P PQA L Q P+ +S Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639 Score = 52.0 bits (123), Expect = 2e-06 Identities = 86/311 (27%), Positives = 116/311 (37%), Gaps = 65/311 (20%) Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362 G S P A H GLQ+ R PQ + P A P Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRP--------------------PQVTPPRKDAA-P 294 Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVS------PLTLSPGPEAHQGFSRQLSSTSPLA 416 +L LS+ L+T + SG R PP P TL P P L+ SP A Sbjct: 295 ALG--PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--LAPPSPSA 350 Query: 417 PYPTSQMVSSDRS--------QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAP 468 P P+ Q + S + ++ P +A + PP P LT P LQ P +P A Sbjct: 351 P-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA- 408 Query: 469 AQQPQAASSLPQSDFQ-------LLPAQ-GSSLTNFFPDVGFDQQSMRPGPAFPQQVPLV 520 QA +SL Q + P Q +SLT+ + + P + P Q PL Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS------PSRPASTPPDSPPLQAPLS 462 Query: 521 QQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPL 580 S LQ S SP S+ P TI P + L+S + P+ L+ PL Sbjct: 463 LPASPPLQTSLSPAVSPLSS----PLTIHP------LQALSSLASHSPQAPLSSLIMPPL 512 Query: 581 EEELQIEPLSL 591 E + + P SL Sbjct: 513 ETQSSLAPPSL 523 Score = 45.8 bits (107), Expect = 1e-04 Identities = 71/270 (26%), Positives = 100/270 (37%), Gaps = 39/270 (14%) Query: 263 PFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSS 322 P L+ S P T+L + P S T H ++S + ++ P A I Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVS-PLSSPLTIHPLQALS--SLASHSPQAPLSSLIMPPL 512 Query: 323 GLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS--LSNPSLSTTNLS 380 QSS + PS+Q +SL P ++P+ + P L+ S L+ P L T Sbjct: 513 ETQSSLAPPSLQTP------PASLTTPPLENLPSLAP--PPLQTASAPLTTPHLETPPCP 564 Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440 P + PP SPLT +P PE + P P L LP+ + Sbjct: 565 APCPLQAPP-SPLT-TPPPETPSSIATPPPQAPPALASPP----------LQGLPSPPLS 612 Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500 ++ PPP AP L P LQ P +P A A+ PQ+ L V Sbjct: 613 PLATPPP-QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------------V 658 Query: 501 GFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530 Q P P+ P Q P S + S Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688 Score = 43.5 bits (101), Expect = 6e-04 Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 13/100 (13%) Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQ 441 PS PP+SPL +P P+A + L +P +P P+ + Q F P A Sbjct: 634 PSPPASPPLSPLA-TPSPQAPNALAVHLLQ-APFSPPPSPPV------QAPFSPP-ASPP 684 Query: 442 VSPP--PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLP 479 VSP PP AP L P LQ P P PA P + S+ P Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATP 722 Score = 40.4 bits (93), Expect = 0.005 Identities = 59/225 (26%), Positives = 74/225 (32%), Gaps = 23/225 (10%) Query: 350 PQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPG--PEAHQGFSR 407 P PNA A+H FS S P+ PPVSP P P + Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA---SPPVSPSATPPSQAPPSLAAPPL 704 Query: 408 QLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPP----------PPYPAPQELTQP 457 Q+ + P +P + ++ Q SPP PP P L P Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764 Query: 458 LLQQPRAPEAPAQQ-------PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510 LQ P +P A PQA +L Q LP+ +S P M P Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824 Query: 511 PAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTS 555 P Q P V + LQ SP P T PD+S S Sbjct: 825 ATPPPQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868 Score = 36.6 bits (83), Expect = 0.070 Identities = 82/322 (25%), Positives = 118/322 (36%), Gaps = 49/322 (15%) Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363 AA T +G+ + S+R P + K+V S+S ++ + S P+A P+ Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238 Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSP-------LA 416 R S S LS+ SGPS R P P P+ Q R T P L Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RPPQVTPPRKDAAPALG 297 Query: 417 PYPTSQMVSSDRSQLSFLPTEAQAQVSPPP-----PYPAPQELTQPLLQQ-PRAPEAPAQ 470 P +S + + P+ +A+ PPP P PA + PL P AP +P+ Sbjct: 298 PLSSSPLATPS-------PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350 Query: 471 QPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530 P Q LP+ ++ + P M+ P+ Q +P +Q S Sbjct: 351 PP---------SLQTLPSPPATPPSQAPP-SMTTPPMQAPPSL-QTIPPIQVPHSLTSPS 399 Query: 531 FHLRPSPYSNCG-----SLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQ 585 PSP + SL + L + + L A L S TP P LQ Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQ 458 Query: 586 IEPLSLDGLNMLSDSSMGLLDP 607 PLSL L S + P Sbjct: 459 -APLSLPASPPLQTSLSPAVSP 479 Score = 34.3 bits (77), Expect = 0.35 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 9/112 (8%) Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPY------PTSQMVSSDRSQLSFLP 435 PS P+SPL P P+A + P P P S S S L+ P Sbjct: 770 PSPPASLPMSPLA-KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828 Query: 436 TEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487 +A ++ P P P LQ PR P P P + S P+ L P Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAP 878 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 51.6 bits (122), Expect = 2e-06 Identities = 63/215 (29%), Positives = 83/215 (38%), Gaps = 41/215 (19%) Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSR----SNPSIQATLNKTVLSSSLNNHPQTSVPNAS 358 G S P A H GLQ+ R + P A LSSS P S P + Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306 Query: 359 ALHPSLRLFS---LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ- 408 + PSL+ + PS +TT+L P+ + PP+SPL +P P+A + Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPP 365 Query: 409 -LSSTSPLAPYPTSQMVSSDRS----------QLSFLPTEA---QAQVSPP--------- 445 + SP A P S + + Q F P + QA SPP Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425 Query: 446 -PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLP 479 PP AP L P LQ P P PA P + S+ P Sbjct: 426 TPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATP 458 Score = 40.4 bits (93), Expect = 0.005 Identities = 60/222 (27%), Positives = 82/222 (36%), Gaps = 29/222 (13%) Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379 + GLQ S + + T LSS + P + HPS + +L + Sbjct: 221 AGGGLQRPASR---SLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQV 276 Query: 380 SGPSRRRQPPVSPLTLSP----GPEAHQGFSRQLS-STSPLAPY-PTSQMVSSDRSQL-- 431 + P + P + PL+ SP P A S S T P P P SQ +S S Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336 Query: 432 ---SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPA 488 SFLP+ + ++ PPP AP L P LQ P +P A A+ PQ+ L Sbjct: 337 ATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-- 393 Query: 489 QGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530 V Q P P+ P Q P S + S Sbjct: 394 -----------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 51.2 bits (121), Expect = 3e-06 Identities = 74/292 (25%), Positives = 107/292 (36%), Gaps = 36/292 (12%) Query: 321 SSGLQSSRSNPSIQATLNKTVLSSSLNNHPQ----TSVPNASALHPSLRLFSLSNPSLST 376 S L++ S P + L+ S L+ P+ + P AS L P +S P + Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588 Query: 377 TNLSGPSRRRQ-PPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLP 435 P R PP LSP PE SPL+P P + +S P Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEE-----------SPLSPPPEASRLSPPPEDSPMSP 637 Query: 436 TEAQAQVSPPP------PYPAPQELTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQ 484 ++ +SPPP P P L+ P + P +P E+P P AS L P D Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697 Query: 485 LLPAQGSSLTNFFPD-----VGFDQQSMRPGPAFPQQVPLVQQGSRELQ-DSFHLRPSPY 538 P S + P+ + ++ + P P PQ P + + + HL P P Sbjct: 698 TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE 757 Query: 539 SNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPF--PLEEELQIEP 588 S P P S + A+ P +S + P P EEL + P Sbjct: 758 EPHLS-PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808 Score = 47.0 bits (110), Expect = 5e-05 Identities = 79/281 (28%), Positives = 108/281 (38%), Gaps = 56/281 (19%) Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390 P ++A LN+ + P P S L P P S T+ + R PP Sbjct: 428 PQLEAPLNEEM--------PLLPPPEESPLSPP--------PEESPTSPPPEASRLSPPP 471 Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPP---PP 447 L SP PEA SR L SPL+P P +S F P E ++ +SPP PP Sbjct: 472 EELPASPLPEALH-LSRPLEE-SPLSPPPEESPLSPPPESSPFSPLE-ESPLSPPEESPP 528 Query: 448 YPA-------PQE---LTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQLLPAQGSS 492 PA P E L+ P + P +P E P P AS L P + + P S Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588 Query: 493 LTNFFPDVG-----FDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNT 547 + P+ F++ + P P++ PL ++ L P P + S P Sbjct: 589 PMSPPPEASRLFPPFEESPLSPP---PEESPLSPP-----PEASRLSPPPEDSPMSPP-- 638 Query: 548 ILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEP 588 P+ S S L+ LP VS +P P E L P Sbjct: 639 --PEESPMSPPPEVSRLSPLPVVSRL--SPPPEESPLSPPP 675 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/165 (25%), Positives = 63/165 (38%), Gaps = 13/165 (7%) Query: 325 QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384 +S S P ++ L+ SS + ++ + PS L + +P + LS P Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550 Query: 385 RR--QPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQV 442 PP L SP PEA + SP++P P +S P ++ + Sbjct: 551 ESPLSPPPEELPTSPPPEASR--LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608 Query: 443 SPPP------PYPAPQELTQPLLQQPRAP---EAPAQQPQAASSL 478 SPPP P P L+ P P +P E+P P S L Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653 Score = 35.4 bits (80), Expect = 0.16 Identities = 61/246 (24%), Positives = 94/246 (38%), Gaps = 28/246 (11%) Query: 338 NKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSP 397 ++T+LS Q ++ P L+ FS T L+G + P + Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKP-LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039 Query: 398 GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-FLPTEAQAQVSPPPPYPAPQELTQ 456 GP HQG PLA T + ++++ ++ L ++Q + P P P P L Sbjct: 4040 GPSTHQG--------GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ- 4090 Query: 457 PLLQQPRAPEAPAQQPQAASSLPQ----SDFQL---LPAQGSSLTNFF--PDVGFDQQ-- 505 LQ P P QQ Q S L S QL ++ SS+ + P V Q Sbjct: 4091 --LQPPL--RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPG 4146 Query: 506 SMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCG-SLPNTILPDSSTSLFKDLNSAL 564 SM PQQ P++++ + +P P G LP + + L L L Sbjct: 4147 SMTQNLLGPQQ-PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205 Query: 565 AGLPEV 570 A P++ Sbjct: 4206 AKNPQL 4211 Score = 33.5 bits (75), Expect = 0.60 Identities = 43/167 (25%), Positives = 61/167 (36%), Gaps = 33/167 (19%) Query: 387 QPPVSPLT----LSPGPEA-HQGFSRQLSSTSP------LAPYPTSQMVSSDRSQLSFLP 435 +P +SP LSP PE H + SP L+P P +S + P Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844 Query: 436 TEAQAQVSP----PPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGS 491 ++ +SP PP P P+ + PE P Q P A LP L P G Sbjct: 845 RPEESHLSPELEKPPLSPRPE----------KPPEEPGQCP-APEELP-----LFPPPGE 888 Query: 492 -SLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSP 537 SL+ + + P P+++PL G L + P P Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL-MPPDP 934 Score = 32.0 bits (71), Expect = 1.7 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 15/84 (17%) Query: 409 LSSTSPLAPYPTSQ------MVSSDRSQLSFLPTEAQAQVSPPPPYPAPQEL---TQPLL 459 L SP AP P +Q + + D QLS P E + SPPP AP T+PL+ Sbjct: 4879 LKQESP-APEPPTQHSYTYNVSNLDVRQLSAPPPE---EPSPPPSPLAPSPASPPTEPLV 4934 Query: 460 QQPRAP--EAPAQQPQAASSLPQS 481 + P P E P P +S P+S Sbjct: 4935 ELPTEPLAEPPVPSPLPLASSPES 4958 Score = 31.6 bits (70), Expect = 2.3 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 35/175 (20%) Query: 389 PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ-AQVSPPP- 446 PV P+ L P P + G SP+ P S Q S +P + +Q SPP Sbjct: 995 PVPPMILPPSPGSPVG------PASPILMEPLPPQCSP-LLQHSLVPQNSPPSQCSPPAL 1047 Query: 447 --PYPAP-------------QELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQL---LPA 488 P+P EL + ++ PE PA +P A S LP L P+ Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107 Query: 489 QGSSLTNF-------FPDVGFDQQSMRPGPA-FPQQVPLVQQGSRELQDSFHLRP 535 +L +F P G D +P P P + +GS L D L P Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162 Score = 31.2 bits (69), Expect = 3.0 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 19/96 (19%) Query: 380 SGPSRRRQP--PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQL----SF 433 +GP + P P P LS GP L P P P+S SQL S Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPV--------LGPVHPTPP-PSSPQEPKRPSQLPSPSSQ 4329 Query: 434 LPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPA 469 LPTEAQ PP +P + P L+ P +PA Sbjct: 4330 LPTEAQL----PPTHPGTPKPQGPTLEPPPGRVSPA 4361 Score = 30.0 bits (66), Expect = 6.6 Identities = 35/129 (27%), Positives = 47/129 (36%), Gaps = 18/129 (13%) Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLA----------PYPTSQMVSSDRSQ 430 G R Q P L+P P +H R S T P A P P S RS Sbjct: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS- 2402 Query: 431 LSFLPTEAQAQVSPPPPYPAPQELTQ-PLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489 LP++ ++V P P Q +Q PL +P + EA P + P++ Sbjct: 2403 ---LPSDPFSRV---PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456 Query: 490 GSSLTNFFP 498 S F P Sbjct: 2457 PQSRDPFAP 2465 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 50.1 bits (118), Expect = 6e-06 Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 38/204 (18%) Query: 310 PAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS- 368 P + + L S S S++ P++ AT + + L+ L + P+ SA PSL+ Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-PPSLQTLPS 356 Query: 369 --LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ--LSSTSPLAPY 418 + PS +TT+L P+ + PP+SPL +P P+A + + SP A Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPLQAPPSPPASP 415 Query: 419 PTSQMVSSDRS----------QLSFLPTEA---QAQVSPP----------PPYPAPQELT 455 P S + + Q F P + QA SPP PP AP L Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475 Query: 456 QPLLQQPRAPEAPAQQPQAASSLP 479 P LQ P P PA P + S+ P Sbjct: 476 APPLQVP--PSPPASPPMSPSATP 497 Score = 43.5 bits (101), Expect = 6e-04 Identities = 63/230 (27%), Positives = 86/230 (37%), Gaps = 24/230 (10%) Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362 G S P A H GLQ+ R Q T + + +L P +S P A+ P Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALG--PLSSSPLATP-SP 309 Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQ 422 S L S + P+L T S S +PL L+P + + L S P + Sbjct: 310 SAALQSQAPPTLPATPHS--SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367 Query: 423 MVSSDRSQL--SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480 + S Q SFLP+ + ++ PPP AP L P LQ P +P A A+ PQ Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426 Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530 + L V Q P P+ P Q P S + S Sbjct: 427 APNALA-------------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463 Score = 35.4 bits (80), Expect = 0.16 Identities = 56/199 (28%), Positives = 80/199 (40%), Gaps = 30/199 (15%) Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363 AA T +G+ + S+R P + K+V S+S ++ + S P+A P+ Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238 Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGF-SRQLS------------ 410 R S S LS+ SGPS R P P P+ Q Q++ Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298 Query: 411 -STSPLA-PYPTSQMVSSDRSQLSFLP--TEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466 S+SPLA P P++ + S L P + Q++ P P P P LQ P Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ--TLPS 356 Query: 467 APAQQP-QAASSLPQSDFQ 484 PA P QA +SL Q Sbjct: 357 PPATPPSQATTSLGSPTLQ 375 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 49.7 bits (117), Expect = 8e-06 Identities = 70/216 (32%), Positives = 79/216 (36%), Gaps = 33/216 (15%) Query: 346 LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLT----LSPGPEA 401 LN H S P ALH +L S PS L P R P VSP L P P Sbjct: 851 LNQHAVVSPP---ALHNALPQ-QPSRPSNRAAALP-PKPARPPAVSPALTQTPLLPQPPM 905 Query: 402 HQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-------FLPT-EAQAQVSPPPPYPAPQE 453 Q L P AP TS + QL LP+ + Q+Q PP P P Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS 965 Query: 454 LTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSS-LTNFFPDVGFD------- 503 + Q L QQP P P Q PQ P L P Q S+ + P G Sbjct: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025 Query: 504 QQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYS 539 QQ P PA PQQV R H + PYS Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPR------HHKSDPYS 1055 Score = 36.2 bits (82), Expect = 0.092 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 7/123 (5%) Query: 430 QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489 Q+ P Q PPP P P Q Q P P P+ QAA ++ S + Q Sbjct: 745 QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ 804 Query: 490 GSSLTNFFPDVGFD------QQSMR-PGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCG 542 L P FD Q + P P P +P + S + H SP + Sbjct: 805 VPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN 864 Query: 543 SLP 545 +LP Sbjct: 865 ALP 867 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 49.7 bits (117), Expect = 8e-06 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%) Query: 287 PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346 P+S D+T G GNS + ++ ++ G+ SSS L S S T + SS Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616 Query: 347 NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406 + Q+SV A+ S+ +P ++++QPP P Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655 Query: 407 RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466 P P P P + Q PPPP PQ+ QP QQP P Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694 Query: 467 APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515 P QQP + S P +P GS S+ P D G S P+ Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751 Query: 516 QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574 + +QQ + + D H P +S + T + S+T L + S LAG P+ + Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810 Query: 575 DTP 577 P Sbjct: 1811 TPP 1813 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 49.7 bits (117), Expect = 8e-06 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%) Query: 287 PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346 P+S D+T G GNS + ++ ++ G+ SSS L S S T + SS Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616 Query: 347 NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406 + Q+SV A+ S+ +P ++++QPP P Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655 Query: 407 RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466 P P P P + Q PPPP PQ+ QP QQP P Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694 Query: 467 APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515 P QQP + S P +P GS S+ P D G S P+ Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751 Query: 516 QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574 + +QQ + + D H P +S + T + S+T L + S LAG P+ + Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810 Query: 575 DTP 577 P Sbjct: 1811 TPP 1813 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 49.7 bits (117), Expect = 8e-06 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%) Query: 287 PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346 P+S D+T G GNS + ++ ++ G+ SSS L S S T + SS Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616 Query: 347 NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406 + Q+SV A+ S+ +P ++++QPP P Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655 Query: 407 RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466 P P P P + Q PPPP PQ+ QP QQP P Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694 Query: 467 APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515 P QQP + S P +P GS S+ P D G S P+ Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751 Query: 516 QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574 + +QQ + + D H P +S + T + S+T L + S LAG P+ + Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810 Query: 575 DTP 577 P Sbjct: 1811 TPP 1813 >gi|105990535 coagulation factor V precursor [Homo sapiens] Length = 2224 Score = 49.3 bits (116), Expect = 1e-05 Identities = 116/503 (23%), Positives = 188/503 (37%), Gaps = 74/503 (14%) Query: 137 PRQQPPWKDEKHPGF-----RLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPY 191 PR P + E + F + + L+++N +++L T T P +G W A Sbjct: 1045 PRTFHPLRSEAYNTFSERRLKHSLVLHKSN-ETSLPTDLNQTLPSMDFG------WIASL 1097 Query: 192 MGFCDGENNGHGEVASFPGPLK----EENLLNVPKPLPKQLWETKEIQSLSGRPRSCDV- 246 +N G+ + PG + EE+ P P Q+ T + S P ++ Sbjct: 1098 PDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHSTSDPSHRSSSPELSEML 1157 Query: 247 ---GGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVG 303 +FP + + S T S PDL+ + S L + + D ++S Sbjct: 1158 EYDRSHKSFPTDISQMSPSSEHEVWQTVIS-PDLSQVTLSPELSQTNLSPDLSHTTLSPE 1216 Query: 304 NSVNNIPAAMTHLGIR---SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 N+ A+ + I S + L S+ ++ L++T LS L+ + L Sbjct: 1217 LIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSPELSQTNLSPALGQMPL 1276 Query: 361 HPSLRLFSLS-----------------NPSLSTTNLSGPSRRRQPPVSP----LTLSPGP 399 P L +LS +P LS TNLS Q P+SP TLS Sbjct: 1277 SPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLS--PALGQMPISPDLSHTTLSLD- 1333 Query: 400 EAHQGFSRQLSSTS--------PLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAP 451 + S +LS T+ PL+P P+ +S D SQ + P +Q +SP + Sbjct: 1334 FSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELSQTNLSPD---LSE 1390 Query: 452 QELTQPLLQQPRAPEAPAQQPQAASSLPQSDF-----QLLPAQGSSLTNFFPDVGF---- 502 L L Q P P+ Q + L ++D Q+ + S PD+ Sbjct: 1391 MPLFADLSQIPLTPD--LDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSPDISDTTLL 1448 Query: 503 -DQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPD-SSTSLFKDL 560 D + P P Q+ + S+ L PY + G +P+ P + T L K+ Sbjct: 1449 PDLSQISPPPDL-DQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPSSPTLNDTFLSKEF 1507 Query: 561 NS-ALAGLPEVSLNVDTPFPLEE 582 N + GL + + P EE Sbjct: 1508 NPLVIVGLSKDGTDYIEIIPKEE 1530 >gi|239756297 PREDICTED: hypothetical protein [Homo sapiens] Length = 525 Score = 48.9 bits (115), Expect = 1e-05 Identities = 65/249 (26%), Positives = 93/249 (37%), Gaps = 31/249 (12%) Query: 270 TGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRS 329 TG +LP + PLP G++ G +V P +T QSSR Sbjct: 209 TGPTLPGGRESSEAYPLP--------QLGAIGSGQAVAYGPFVLT----------QSSRP 250 Query: 330 NPSIQATLNKTVLSSSL-NNHPQTSVPNAS--ALHPSLRLFSLSNPSLSTTNLSG----- 381 + +L ++ S + ++ P T + P L SL P T L+ Sbjct: 251 TDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPRTPTPGLTEGGGTG 310 Query: 382 -PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440 PS++R+ P SP T GP+ G + S + P P P S DR L +A Sbjct: 311 LPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRA 366 Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500 + PYPA EL P Q +P+ P + L PA S+L P Sbjct: 367 PLGSALPYPARSELAPPGAQDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 426 Query: 501 GFDQQSMRP 509 F + RP Sbjct: 427 QFTFRKRRP 435 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 48.5 bits (114), Expect = 2e-05 Identities = 44/161 (27%), Positives = 60/161 (37%), Gaps = 11/161 (6%) Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440 GPS +P + P + P QG Q P P V+ L+ P Sbjct: 1975 GPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLG 2034 Query: 441 QV--SPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL---PQSDFQLLPAQGSSLTN 495 QV SP P Q+ Q LL+ R+P +P QQ Q S L PQ + + + N Sbjct: 2035 QVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN 2094 Query: 496 FFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPS 536 P Q + P PQ P +Q + Q H P+ Sbjct: 2095 SNP------QPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA 2129 Score = 38.9 bits (89), Expect = 0.014 Identities = 58/201 (28%), Positives = 77/201 (38%), Gaps = 49/201 (24%) Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360 S G +V NIP A SS P QA ++ SSS + P + Sbjct: 772 SQGMNVTNIPLA------------PSSGQAPVSQAQMS----SSSCPVNSPIMPPGSQGS 815 Query: 361 HPSLRLFSLSNPSLSTTNLSG-PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYP 419 H + L P+L + S PSR P +P ++ ++Q +T+ AP P Sbjct: 816 H--IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIG---------AQQPPATTIPAPVP 864 Query: 420 TSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQ--PRAPEAP-AQQPQ--- 473 T +P Q+Q PPP P T L QQ P P AP A QPQ Sbjct: 865 TPPA----------MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQP 914 Query: 474 -----AASSLPQSDFQLLPAQ 489 A+S+P LLP Q Sbjct: 915 RSQQSTAASVPTPTAPLLPPQ 935 Score = 34.3 bits (77), Expect = 0.35 Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 11/81 (13%) Query: 400 EAHQGFSRQLSSTSPLAPYPTS-------QMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452 +A+Q Q SP+ P P S S Q +P QV P P P+P+ Sbjct: 2258 QAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPR 2317 Query: 453 ELTQPLLQQPRAPEAPAQQPQ 473 +QP P + +P QPQ Sbjct: 2318 PQSQP----PHSSPSPRMQPQ 2334 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 48.5 bits (114), Expect = 2e-05 Identities = 104/436 (23%), Positives = 160/436 (36%), Gaps = 51/436 (11%) Query: 190 PYMGFCDGENNGHGEVASFPGPLKEENLLNVPKP-------LPKQLWETKEIQSLSGRPR 242 P F G+ N H F G L + ++ V + L KQ + QS G Sbjct: 193 PGGSFLFGKMNPHA--VQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLF 250 Query: 243 SCDVGGGNAFPHNGQNLGL------SPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHH 296 S D G F + LGL +P LG+L G P T + P T+ H Sbjct: 251 SQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRG-PRGTVAPATPTKPQRTSPTNPH 309 Query: 297 FGSMSVGN-----------SVNNIPAAMTHLGIRSSSGL-QSSRSNPSIQATLNKTVLSS 344 M+VG S +N M + S+ + + + PS + T K S Sbjct: 310 -QHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSL 368 Query: 345 SLN-NHPQTSVPNASALHPSLRLF--SLSNPSLST------TNLSGPSRRRQPPVSPLTL 395 + P TS+ + HP+ + S + +L T T+ P+R +P P+ Sbjct: 369 PTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQR 428 Query: 396 SPG-PEAHQGFSRQLSST--SPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452 +PG P +R L T S P PT + + + P A+ PPP+ A Sbjct: 429 NPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALS 488 Query: 453 ELTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510 P R+ PA P + +S P++ +P GS+ T +G + S + G Sbjct: 489 SSPAPTPGSTRSTRPPATMVPPTSGTSTPRT-APAVPTPGSAPTGSKKPIG-SEASKKAG 546 Query: 511 PAFPQQVPLVQQGSRELQD----SFHLRPSPYSNCGSLPNT--ILPDSSTSLFKDLNSAL 564 P + P+ + + +D RPSP S T ++ + L Sbjct: 547 PKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTS 606 Query: 565 AGLPEVSLNVDTPFPL 580 +G L TPFPL Sbjct: 607 SGYSIFHLAGSTPFPL 622 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 47.4 bits (111), Expect = 4e-05 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 17/194 (8%) Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402 S QT N + HP + S S T + PS ++QP P L S P Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519 Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462 Q S+ SP APYP+ Q + Q PPY PQ + QQP Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565 Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522 + P QAA PQS Q S F P Q S + + + Sbjct: 566 QQPAPSTLSQQAAYPQPQS--QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG 623 Query: 523 GSRELQDSFHLRPS 536 G ++ S RPS Sbjct: 624 GQEDMNLSLQSRPS 637 Score = 35.8 bits (81), Expect = 0.12 Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 32/178 (17%) Query: 372 PSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSS--TSPLAPYPTSQMVSSDRS 429 PS + + PSR P + H + Q S+ T +P+P+ Q + Sbjct: 1311 PSNPDSGMYSPSR-----YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365 Query: 430 QLSFLPTEAQAQVSPPPP------YPAPQELTQPLLQQPRAPEA---PAQQPQAASSLPQ 480 Q ++ PP Y P Q QQ + P A PA Q QAA PQ Sbjct: 1366 QQNY-KRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 Query: 481 SDF-----QLLPAQGSSLT---------NFFP-DVGFDQQSMRPGPAFPQQVPLVQQG 523 D PA ++ T N FP G D+ S PG Q +P G Sbjct: 1425 QDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 47.4 bits (111), Expect = 4e-05 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 17/194 (8%) Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402 S QT N + HP + S S T + PS ++QP P L S P Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519 Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462 Q S+ SP APYP+ Q + Q PPY PQ + QQP Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565 Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522 + P QAA PQS Q S F P Q S + + + Sbjct: 566 QQPAPSTLSQQAAYPQPQS--QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG 623 Query: 523 GSRELQDSFHLRPS 536 G ++ S RPS Sbjct: 624 GQEDMNLSLQSRPS 637 >gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Homo sapiens] Length = 1990 Score = 47.4 bits (111), Expect = 4e-05 Identities = 52/210 (24%), Positives = 87/210 (41%), Gaps = 19/210 (9%) Query: 319 RSSSGLQSSRSNPSIQATLNKTVLSSS-LNNHPQTSVPNASAL-HPSLRLFSLSNPSLST 376 R S GL +S PS + +SSS L +H ++S++ P+ + + ++P+LS Sbjct: 1432 RPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSP 1491 Query: 377 TNLSGPSRRRQPPVSPL------TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQ 430 T+ + R P SP SP P QG SPL P + S Sbjct: 1492 THQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESM 1551 Query: 431 LSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAP-----EAPAQQPQAASSLPQSDFQL 485 + ++Q P Y ++Q L +P++P + P Q PQ ++PQ +L Sbjct: 1552 SVY-----RSQSGSPVRYQQETSVSQ-LPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRL 1605 Query: 486 LPAQGSSLTNFFPDVGFDQQSMRPGPAFPQ 515 PA+ + + P ++ P A+ Q Sbjct: 1606 QPAKAQIVRSNQPSPAVHSSTVIPTGAYGQ 1635 Score = 32.3 bits (72), Expect = 1.3 Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 15/183 (8%) Query: 305 SVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNK--TVLSSSLNNHPQTSVPNASALHP 362 S + P + L + SS S +P + + + +V + + HP T P + Sbjct: 1722 SASYYPVCHSKLDLERSS---SQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSV 1778 Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAP----Y 418 LR SN ST+NL+ P+ R + + + P + R SP++P Y Sbjct: 1779 GLRFSPSSNSISSTSNLT-PTFRPSSSIQQMEIPLKP----AYERSCDELSPVSPTQGGY 1833 Query: 419 PTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL 478 P+ S + + A+ Q P + + + +P +P PQ S Sbjct: 1834 PSEPTRSRTTPFMGIIDKTARTQ-QYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFS 1892 Query: 479 PQS 481 P S Sbjct: 1893 PPS 1895 >gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo sapiens] Length = 488 Score = 46.6 bits (109), Expect = 7e-05 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 12/162 (7%) Query: 355 PNASALHPSLRLFSLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSS 411 PN L P SL P+ T G PS++R+ P SP T GP+ G + S Sbjct: 257 PNVHRLPPPP---SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASL 309 Query: 412 TSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQ 471 + P P P S DR L + + PYPA EL P + +P+ Sbjct: 310 SGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPC 369 Query: 472 PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMR--PGP 511 P + L PA S+L P F + +R PGP Sbjct: 370 PGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 411 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 46.6 bits (109), Expect = 7e-05 Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%) Query: 11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66 N + SE+I+ + ++EET A ++ T+ L R Q L L R G S P ++ Sbjct: 68 NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124 Query: 67 SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124 Q S S PS + +V GL + P+R P H P Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167 Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181 S QP D S PRQ P E HP T S + + P P Y G Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222 Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241 G P MG G G +S GP + + P P + + + +P Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275 Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293 + VGGGN FPH NL P L LN + P + PLP L + Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332 Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341 H G ++ S +++P A + SS S+ S A+ + + Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391 Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400 SSS + P + ++P+ P S+SN P + QP + Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433 Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460 S+ + S P P P +++++ + P AQ + PP Q Q Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488 Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516 Q + + QQ Q S P P +G S + P + S+RP P P Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548 Query: 517 VP 518 +P Sbjct: 549 LP 550 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 46.6 bits (109), Expect = 7e-05 Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%) Query: 11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66 N + SE+I+ + ++EET A ++ T+ L R Q L L R G S P ++ Sbjct: 68 NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124 Query: 67 SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124 Q S S PS + +V GL + P+R P H P Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167 Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181 S QP D S PRQ P E HP T S + + P P Y G Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222 Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241 G P MG G G +S GP + + P P + + + +P Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275 Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293 + VGGGN FPH NL P L LN + P + PLP L + Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332 Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341 H G ++ S +++P A + SS S+ S A+ + + Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391 Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400 SSS + P + ++P+ P S+SN P + QP + Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433 Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460 S+ + S P P P +++++ + P AQ + PP Q Q Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488 Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516 Q + + QQ Q S P P +G S + P + S+RP P P Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548 Query: 517 VP 518 +P Sbjct: 549 LP 550 >gi|236459851 ubinuclein 2 [Homo sapiens] Length = 1347 Score = 45.8 bits (107), Expect = 1e-04 Identities = 70/313 (22%), Positives = 117/313 (37%), Gaps = 23/313 (7%) Query: 275 PDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNN----IPAAMTHLGIRSSSGLQSSRSN 330 P + L STP P + H S +V ++ + A ++ + + S ++ Sbjct: 977 PLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAAS 1036 Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390 P + A+ L + ++ P PSL + PS+ST +S + +P V Sbjct: 1037 PKLAASPKPATSPKPLPSPKPSASPK-----PSLS----AKPSVSTKLISKSNPTPKPTV 1087 Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450 SP + SP QG S+ SP+ P+ +S L+ LP+ + + P A Sbjct: 1088 SPSSSSPNALVAQG--SHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQA 1145 Query: 451 PQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510 P +LT A ++P S L + G++ T+ G Q Sbjct: 1146 PSKLTN---SSSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKP 1202 Query: 511 PAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTIL--PDSSTSLFKDLNSALAGLP 568 + P + P GS + S + P T++ P S T+ L GL Sbjct: 1203 LSTPHR-PSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGL- 1260 Query: 569 EVSLNVDTPFPLE 581 V + + FPLE Sbjct: 1261 -VPVTMPFQFPLE 1272 Score = 34.3 bits (77), Expect = 0.35 Identities = 32/124 (25%), Positives = 42/124 (33%), Gaps = 11/124 (8%) Query: 368 SLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSD 427 SLS GP R + P P L P P + +P P P S Sbjct: 11 SLSPVRRREAEYPGPEREPEYPREPPRLEPQPYREPA---RAEPPAPREPAPRSDAQPPS 67 Query: 428 RSQLSFLPTEAQAQVSPP------PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQS 481 R + LP ++ PP PP P P PL QP P A + + P+ Sbjct: 68 REKP--LPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRE 125 Query: 482 DFQL 485 +L Sbjct: 126 TVRL 129 Score = 32.0 bits (71), Expect = 1.7 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 6/111 (5%) Query: 428 RSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487 R + + E + + PP PQ +P +P AP PA + A P S + LP Sbjct: 17 RREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQ---PPSREKPLP 73 Query: 488 AQGSSLTNFFPDVGFDQQSMRPGPAFP-QQVPLVQQGSRELQDSFHLRPSP 537 + S P + ++ RP P P +PL RE P P Sbjct: 74 QREVSRAE--PPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRP 122 >gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo sapiens] Length = 800 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 9/149 (6%) Query: 368 SLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMV 424 SL P+ T G PS++R+ P SP T GP+ G + S + P P P Sbjct: 395 SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPP 450 Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQ 484 S DR L + + PYPA EL P + +P+ P + Sbjct: 451 SRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGL 510 Query: 485 LLPAQGSSLTNFFPDVGFDQQSMR--PGP 511 L PA S+L P F + +R PGP Sbjct: 511 LSPAPRSALGETAPTAQFTFRKVRNPPGP 539 >gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] Length = 1543 Score = 45.4 bits (106), Expect = 2e-04 Identities = 53/194 (27%), Positives = 74/194 (38%), Gaps = 21/194 (10%) Query: 308 NIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLF 367 NIP A H ++ S QS S+ A N+ V L N T+V A S + Sbjct: 688 NIPIAPIHSSAQAMSPTQSIGLVQSLLA--NQNVQLDVLTNQT-TAVGTAEHAGDSATQY 744 Query: 368 SLSNPSLSTTNLSGPSRR-----RQPPVSPLTLSPGPEA--------HQGFSRQLSSTSP 414 +SN + + S + PP PL+L P P+ H + S Sbjct: 745 PVSNRYSNPGQVIFGSVEMGRIIQNPP--PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSA 802 Query: 415 LAPYPTSQMVSSDRSQLSFLPTEAQA-QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQ 473 A PT Q+ + + + P E Q +++PPPPYP P P P QP Sbjct: 803 KALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPP--PPLPPPQPP 860 Query: 474 AASSLPQSDFQLLP 487 L + DF L P Sbjct: 861 VDVCLKKGDFSLYP 874 >gi|33186895 selenoprotein V [Homo sapiens] Length = 346 Score = 44.7 bits (104), Expect = 3e-04 Identities = 62/241 (25%), Positives = 91/241 (37%), Gaps = 22/241 (9%) Query: 346 LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR-RRQPPVSPLT--LSPGPEAH 402 +NN +T P+++ S+R S P+ + T L P+ R + P+ LT L+P P Sbjct: 1 MNNQARTPAPSSARTSTSVRA---STPTRTPTPLRTPTPVRTRTPIRTLTPVLTPSPA-- 55 Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462 G S + + +P A PT + +P A A + P P P P P+ Sbjct: 56 -GTSPLVLTPAP-AQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPVPVRNPTPVPTPA 113 Query: 463 RAPEAPAQQP-QAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQ 521 R P + P A + L LP S L P + P P ++PL+ Sbjct: 114 RTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALP--------LDPPPEPAPELPLLP 165 Query: 522 QGSRELQDSFHLRPSPYSNCGSLPN---TILPDSSTSLFKDLNSALAGLPEVSLNVDTPF 578 + E S L PS S G P T P ++ S L+ P D P Sbjct: 166 EEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFRADPSAIGLADPPI 225 Query: 579 P 579 P Sbjct: 226 P 226 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 44.3 bits (103), Expect = 3e-04 Identities = 57/289 (19%), Positives = 97/289 (33%), Gaps = 30/289 (10%) Query: 325 QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384 Q S++ PS+ T+ + + P+ A+A F + T +L P Sbjct: 1110 QPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKA 1169 Query: 385 RRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSP 444 +R P +P + + S + ++ P P + + + +E + Q +P Sbjct: 1170 QRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP 1229 Query: 445 PPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQ 504 P P P P+ T P P P + + ++ P++ P+ S P G + Sbjct: 1230 PAPPPLPETWTPTARSSPPLP--PPAEERTSAKGPETMASKFPSSSSDWR--VPGQGLEN 1285 Query: 505 QSMRPGPAFPQQVPLVQQGSRELQDS-------------------FHLRPSPYSNC-GSL 544 + P P P P V G S +RP P S+ Sbjct: 1286 RGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSV 1345 Query: 545 PNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDG 593 N +L + D A LPE P P + L P ++ G Sbjct: 1346 DNRVLSE------VDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILG 1388 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 43.9 bits (102), Expect = 4e-04 Identities = 55/213 (25%), Positives = 77/213 (36%), Gaps = 26/213 (12%) Query: 284 TPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLS 343 TP P S TT SV N + +P A S+S Q P+ +AT + S Sbjct: 1343 TPKPTSR-TTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPVTPEPTSRATRGRKNRS 1399 Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQ 403 S P+T VP A L PS P ++ G + R + PE Sbjct: 1400 SGKT--PETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPE--- 1454 Query: 404 GFSRQLSSTSPLAPYPTSQMV--SSDRSQL----SFLPTEAQAQVSPPPPYPAPQELTQP 457 S+ P+ P PTSQ +DRS + + +PT + Q S P E T Sbjct: 1455 -LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSR 1513 Query: 458 LLQ-----------QPRAPEAPAQQPQAASSLP 479 + + P AP QP ++ P Sbjct: 1514 TTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1546 Score = 38.1 bits (87), Expect = 0.024 Identities = 41/169 (24%), Positives = 64/169 (37%), Gaps = 10/169 (5%) Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379 S+S Q P+ QAT +T SS P+T VP A L PS P ++ Sbjct: 1417 STSTDQPVTPEPTSQATRGRTNRSSVKT--PETVVPTAPELQPSTSTDQPVTPEPTSQAT 1474 Query: 380 SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439 G + R + PE S+ P+ PTS+ +++ S E Sbjct: 1475 RGRTDRSSVKTPETVVPTAPE----LQASASTDQPVTSEPTSRTTRGRKNRSSVKTPET- 1529 Query: 440 AQVSPPPPYPAPQELT-QPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487 V P P P T QP+ +P + + +++ P+S + P Sbjct: 1530 --VVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576 Score = 37.7 bits (86), Expect = 0.032 Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%) Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379 S+S Q S P+ QAT + SS P+ VP A L PS P T+ Sbjct: 1253 STSTDQPVTSEPTYQATRGRKNRSSVKT--PEPVVPTAPELRPSTSTDRPVTPK--PTSR 1308 Query: 380 SGPSRRRQPPV-SPLTLSP-GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTE 437 + SR V +P T+ P PE S+ P+ P PTS+ S + S E Sbjct: 1309 TTRSRTNMSSVKTPETVVPTAPE----LQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPE 1364 Query: 438 AQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQS 481 + ++P P E QP+ +P + ++ +++ P++ Sbjct: 1365 STVPIAPELPPSTSTE--QPVTPEPTSRATRGRKNRSSGKTPET 1406 Score = 31.2 bits (69), Expect = 3.0 Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 23/152 (15%) Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390 PSI+ T+ KT S HP P + T S R P Sbjct: 1072 PSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPK--------PKIRTRKSS-----RMTPF 1118 Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450 P T S PE H S+ P+ P PTSQ + RS+ + + V P P Sbjct: 1119 -PAT-SAAPEPHPS----TSTAQPVTPKPTSQ---ATRSRTNRSSVKTPEPVVPTAPELQ 1169 Query: 451 PQELT-QPLLQQPRAPEAPAQQPQAASSLPQS 481 P T QP+ +P + ++ +++ P++ Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPET 1201 Score = 29.6 bits (65), Expect = 8.6 Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 7/130 (5%) Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379 S+S Q S P+ + T + SS P+T VP A L PS P ++ Sbjct: 1499 SASTDQPVTSEPTSRTTRGRKNRSSVKT--PETVVPAAPELQPSTSTDQPVTPEPTSRAT 1556 Query: 380 SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439 G + R + PE SR T P PTS+ + R+ S + T Sbjct: 1557 RGRTNRSSVKTPESIVPIAPELQPSTSRNQLVT----PEPTSR-ATRCRTNRSSVKTPEP 1611 Query: 440 AQVSPPPPYP 449 + P P+P Sbjct: 1612 VVPTAPEPHP 1621 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 43.9 bits (102), Expect = 4e-04 Identities = 67/275 (24%), Positives = 100/275 (36%), Gaps = 23/275 (8%) Query: 350 PQTSVPNASA-LHPSLRLFSLSNPSLSTTNLSGP--SRRRQPPVSPLTLSPGPEAHQGFS 406 PQ P++S+ L S ++P S T GP S +P +P + +PGP + Q Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP-SRTPGPPSAQSSP 1080 Query: 407 RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466 +PL +Q + R P + +PP P P +QP Q A Sbjct: 1081 IDAQPATPLPQKDPAQPLEPKRPPPP-RPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139 Query: 467 APAQQPQAASSLP--------------QSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPA 512 PA A ++P S +L P S + F + ++P A Sbjct: 1140 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1199 Query: 513 FPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFK---DLNSALAGLPE 569 FP Q L R LQ+ +P G PN P + L S + P+ Sbjct: 1200 FPPQSSLPPPAQR-LQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258 Query: 570 VSLNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGL 604 V N + E L+I+P N+L+ S L Sbjct: 1259 VKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQL 1293 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,143,101 Number of Sequences: 37866 Number of extensions: 1679878 Number of successful extensions: 10177 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 787 Number of HSP's that attempted gapping in prelim test: 7422 Number of HSP's gapped (non-prelim): 2419 length of query: 618 length of database: 18,247,518 effective HSP length: 108 effective length of query: 510 effective length of database: 14,157,990 effective search space: 7220574900 effective search space used: 7220574900 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.