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Search of human proteins with 156105693
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156105693 PPAR-alpha interacting complex protein 285 isoform
1 [Homo sapiens]
(2649 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 5370 0.0
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 4195 0.0
gi|54792138 helicase with zinc finger domain [Homo sapiens] 482 e-135
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] 184 1e-45
gi|14251207 MOV10-like 1 [Homo sapiens] 139 3e-32
gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i... 130 2e-29
gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like is... 130 2e-29
gi|190014625 DIS3 mitotic control isoform b [Homo sapiens] 119 5e-26
gi|190014623 DIS3 mitotic control isoform a [Homo sapiens] 119 5e-26
gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap... 117 1e-25
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi... 117 1e-25
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens] 115 4e-25
gi|113722133 senataxin [Homo sapiens] 109 3e-23
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2... 102 5e-21
gi|122937299 DNA replication helicase 2 homolog [Homo sapiens] 90 3e-17
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens] 79 6e-14
gi|38788372 aquarius [Homo sapiens] 59 5e-08
gi|27414497 zinc finger CCCH-type containing 7A [Homo sapiens] 54 3e-06
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens] 46 4e-04
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 37 0.20
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 37 0.26
gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens] 36 0.44
gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens] 36 0.44
gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens] 36 0.44
gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens] 36 0.58
gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens] 36 0.58
gi|19913396 smoothelin isoform b [Homo sapiens] 35 0.98
gi|19913394 smoothelin isoform c [Homo sapiens] 35 0.98
gi|19913398 smoothelin isoform a [Homo sapiens] 35 0.98
gi|115527120 nebulin [Homo sapiens] 34 1.7
>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
[Homo sapiens]
Length = 2649
Score = 5370 bits (13929), Expect = 0.0
Identities = 2649/2649 (100%), Positives = 2649/2649 (100%)
Query: 1 MAVWEAEQLGGLQRGDLLTPPAPDGDGRTAPLGQPPGAQLYCPACLVTCHSQEAFENHCA 60
MAVWEAEQLGGLQRGDLLTPPAPDGDGRTAPLGQPPGAQLYCPACLVTCHSQEAFENHCA
Sbjct: 1 MAVWEAEQLGGLQRGDLLTPPAPDGDGRTAPLGQPPGAQLYCPACLVTCHSQEAFENHCA 60
Query: 61 SSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQEWVRRTQ 120
SSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQEWVRRTQ
Sbjct: 61 SSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQEWVRRTQ 120
Query: 121 AVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPLMYQAQERKTQ 180
AVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPLMYQAQERKTQ
Sbjct: 121 AVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPLMYQAQERKTQ 180
Query: 181 YSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTADFQVGVR 240
YSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTADFQVGVR
Sbjct: 181 YSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTADFQVGVR 240
Query: 241 VQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRH 300
VQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRH
Sbjct: 241 VQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRH 300
Query: 301 VVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQL 360
VVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQL
Sbjct: 301 VVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQL 360
Query: 361 VAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALV 420
VAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALV
Sbjct: 361 VAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALV 420
Query: 421 APVPAPDNTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRL 480
APVPAPDNTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRL
Sbjct: 421 APVPAPDNTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRL 480
Query: 481 WHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPL 540
WHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPL
Sbjct: 481 WHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPL 540
Query: 541 LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP 600
LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP
Sbjct: 541 LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP 600
Query: 601 LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGF 660
LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGF
Sbjct: 601 LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPVGF 660
Query: 661 FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRL 720
FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRL
Sbjct: 661 FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRL 720
Query: 721 FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL 780
FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
Sbjct: 721 FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL 780
Query: 781 MFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVS 840
MFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVS
Sbjct: 781 MFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVS 840
Query: 841 ALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNT 900
ALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNT
Sbjct: 841 ALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNT 900
Query: 901 VLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRR 960
VLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRR
Sbjct: 901 VLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRR 960
Query: 961 WPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTE 1020
WPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTE
Sbjct: 961 WPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTE 1020
Query: 1021 AAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLD 1080
AAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLD
Sbjct: 1021 AAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLD 1080
Query: 1081 ESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCSFVPETFE 1140
ESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCSFVPETFE
Sbjct: 1081 ESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCSFVPETFE 1140
Query: 1141 RASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRH 1200
RASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRH
Sbjct: 1141 RASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRH 1200
Query: 1201 ELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERLTAEAR 1260
ELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERLTAEAR
Sbjct: 1201 ELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLERLTAEAR 1260
Query: 1261 HSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVL 1320
HSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVL
Sbjct: 1261 HSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVL 1320
Query: 1321 QKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVP 1380
QKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVP
Sbjct: 1321 QKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVP 1380
Query: 1381 RDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQL 1440
RDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQL
Sbjct: 1381 RDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQL 1440
Query: 1441 KSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHR 1500
KSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHR
Sbjct: 1441 KSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHR 1500
Query: 1501 LRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRS 1560
LRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRS
Sbjct: 1501 LRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRS 1560
Query: 1561 QQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVD 1620
QQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVD
Sbjct: 1561 QQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVD 1620
Query: 1621 LVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLD 1680
LVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLD
Sbjct: 1621 LVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLD 1680
Query: 1681 VVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDK 1740
VVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDK
Sbjct: 1681 VVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDK 1740
Query: 1741 LGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVY 1800
LGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVY
Sbjct: 1741 LGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVY 1800
Query: 1801 SAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELV 1860
SAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELV
Sbjct: 1801 SAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQRRELV 1860
Query: 1861 QVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPG 1920
QVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPG
Sbjct: 1861 QVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPG 1920
Query: 1921 DCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQ 1980
DCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQ
Sbjct: 1921 DCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQ 1980
Query: 1981 GQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTY 2040
GQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTY
Sbjct: 1981 GQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTY 2040
Query: 2041 TWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPD 2100
TWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPD
Sbjct: 2041 TWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPD 2100
Query: 2101 LRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVA 2160
LRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVA
Sbjct: 2101 LRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVA 2160
Query: 2161 VREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCG 2220
VREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCG
Sbjct: 2161 VREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCG 2220
Query: 2221 PSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRS 2280
PSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRS
Sbjct: 2221 PSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRS 2280
Query: 2281 ITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCT 2340
ITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCT
Sbjct: 2281 ITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCT 2340
Query: 2341 CSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNER 2400
CSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNER
Sbjct: 2341 CSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNER 2400
Query: 2401 LQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHA 2460
LQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHA
Sbjct: 2401 LQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHA 2460
Query: 2461 GKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAV 2520
GKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAV
Sbjct: 2461 GKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAV 2520
Query: 2521 LTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSW 2580
LTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSW
Sbjct: 2521 LTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSW 2580
Query: 2581 LKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVR 2640
LKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVR
Sbjct: 2581 LKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVR 2640
Query: 2641 VCRRPTMPS 2649
VCRRPTMPS
Sbjct: 2641 VCRRPTMPS 2649
>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
[Homo sapiens]
Length = 2080
Score = 4195 bits (10879), Expect = 0.0
Identities = 2073/2075 (99%), Positives = 2074/2075 (99%)
Query: 575 TNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 634
+ SAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT
Sbjct: 6 SRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 65
Query: 635 RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG 694
RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG
Sbjct: 66 RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG 125
Query: 695 DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS 754
DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS
Sbjct: 126 DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS 185
Query: 755 RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 814
RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA
Sbjct: 186 RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 245
Query: 815 YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 874
YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST
Sbjct: 246 YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 305
Query: 875 VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE 934
VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE
Sbjct: 306 VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE 365
Query: 935 CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA 994
CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA
Sbjct: 366 CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA 425
Query: 995 MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA 1054
MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA
Sbjct: 426 MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA 485
Query: 1055 EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP 1114
EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP
Sbjct: 486 EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP 545
Query: 1115 PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV 1174
PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV
Sbjct: 546 PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV 605
Query: 1175 QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 1234
QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP
Sbjct: 606 QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 665
Query: 1235 SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE 1294
SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE
Sbjct: 666 SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE 725
Query: 1295 QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD 1354
QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD
Sbjct: 726 QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD 785
Query: 1355 DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD 1414
DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD
Sbjct: 786 DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD 845
Query: 1415 VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE 1474
VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE
Sbjct: 846 VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE 905
Query: 1475 LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534
LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR
Sbjct: 906 LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965
Query: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594
LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT
Sbjct: 966 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025
Query: 1595 RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH 1654
RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH
Sbjct: 1026 RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH 1085
Query: 1655 QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH 1714
QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH
Sbjct: 1086 QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH 1145
Query: 1715 ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG 1774
ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG
Sbjct: 1146 ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG 1205
Query: 1775 SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL 1834
SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL
Sbjct: 1206 SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL 1265
Query: 1835 VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG 1894
VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG
Sbjct: 1266 VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG 1325
Query: 1895 FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA 1954
FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA
Sbjct: 1326 FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA 1385
Query: 1955 TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG 2014
TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG
Sbjct: 1386 TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG 1445
Query: 2015 LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG 2074
LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG
Sbjct: 1446 LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG 1505
Query: 2075 MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI 2134
MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI
Sbjct: 1506 MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI 1565
Query: 2135 PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS 2194
PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS
Sbjct: 1566 PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS 1625
Query: 2195 NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF 2254
NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF
Sbjct: 1626 NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF 1685
Query: 2255 PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE 2314
PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE
Sbjct: 1686 PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE 1745
Query: 2315 DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL 2374
DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL
Sbjct: 1746 DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL 1805
Query: 2375 VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF 2434
VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF
Sbjct: 1806 VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF 1865
Query: 2435 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 2494
PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL
Sbjct: 1866 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 1925
Query: 2495 EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS 2554
EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS
Sbjct: 1926 EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS 1985
Query: 2555 EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL 2614
EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL
Sbjct: 1986 EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL 2045
Query: 2615 RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2649
RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS
Sbjct: 2046 RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2080
>gi|54792138 helicase with zinc finger domain [Homo sapiens]
Length = 1942
Score = 482 bits (1240), Expect = e-135
Identities = 318/962 (33%), Positives = 500/962 (51%), Gaps = 80/962 (8%)
Query: 53 EAFENHCASSEHAQMVAFDQALPWEHRSPPPGLSKFE---LCPK---PDLCEYGDACTKA 106
E ++ S H + + W R PP G++ E LC + +C YG CT A
Sbjct: 143 ETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEEYTLCKRFLEQGICRYGAQCTSA 202
Query: 107 HSAQELQEWVRR--TQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRV 164
HS +EL EW +R ++ ++L+ Q + Y E L+ ++ S S VL+E ++GV+V
Sbjct: 203 HSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSECIEGVKV 262
Query: 165 TCNQPLMYQAQERKTQYSWTFAVHSEEP--LLHVALLKQEPGADFSLVAPGLPPGRLYAR 222
N L +K+ +WTFA+ + L VALL FS++A
Sbjct: 263 EHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVS 322
Query: 223 GERFRVPSSTAD---------------FQVGVRVQAASFGTFEQWVVFDFGRRPVLLQKL 267
E VP + + ++VG+ FGTF Q +VFDFG PVL+Q++
Sbjct: 323 QE---VPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRV 379
Query: 268 GLQLGQGRRPGPCRNLALGHPEEMERWHTGNRHVVPGV--ERTAEQTALMAKYKGPALAL 325
+ + +RW + ++ ++ E T + +L+ +Y+ P A
Sbjct: 380 MIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETTDLEKSLLIRYQIPLSAD 439
Query: 326 EFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQTPALN--M 383
+ SV ++ +NY+ R+H LY EE AQ + ++K L+ Q+ + + ++
Sbjct: 440 QLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGA 499
Query: 384 LFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVP--------APDNTVFEVRL 435
+A G L+ + +L DT G L+ V+ + PVP V+E +
Sbjct: 500 KYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATI 559
Query: 436 ERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDTLPEEQLVV 495
E + +++ ++L L CC L L+P+ +E+QFQ++ + H A+D + + ++
Sbjct: 560 EEK--TKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLF 617
Query: 496 PDLP-TCALP----RPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLIYGPFGTGK 550
PD+ T +P R W R N KQ+ AV I ++PP+LI GP+GTGK
Sbjct: 618 PDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAIT---TPLAIQLPPVLIIGPYGTGK 674
Query: 551 TYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPL 610
T+TLA A ++++ ET++LICTH+NSAAD+YI++Y H +V G+P+A PLRV + +R +
Sbjct: 675 TFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWV 734
Query: 611 SQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQAR---ELRVPVGFFSHILID 667
PV QYC ++ F+ P + ++ +HRVVV T + ++ +L + GFF+HIL+D
Sbjct: 735 KTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLD 794
Query: 668 EAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRLFLCYQQ 726
EAAQ +ECE + PLA A+ TR+VLAGDHMQ++P ++S AR R +LL RL+ Y
Sbjct: 795 EAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPA 854
Query: 727 ETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVA 786
E R++ ENYR +AI+++ S FY K + A GK P H YPL F
Sbjct: 855 EF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPLTFFTAR 906
Query: 787 GSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGAQVSALRQE 845
G ++ + ++ N AE+ +VVE+V+E WP WG + I VV+ + QV +R E
Sbjct: 907 GEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAE 966
Query: 846 LRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSP------------GALAPE 890
LR++ L V+V + G+QFRV+ LSTV HTC+ +P L
Sbjct: 967 LRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYG 1026
Query: 891 FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQ 950
F ++ ++LNT +TRAQS + VVGD +ALCS G C K WE FI C E S+ G++ EQ
Sbjct: 1027 FLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--HGITFEQ 1084
Query: 951 VE 952
++
Sbjct: 1085 IK 1086
Score = 113 bits (282), Expect = 3e-24
Identities = 100/336 (29%), Positives = 149/336 (44%), Gaps = 45/336 (13%)
Query: 2327 RKFELDRHEVILCTCSCAASASLKILDVR-----QILVDEAGMATEPETLIPLVQFPQAE 2381
+K ++ +H V++ T + S L LD+ IL+DEA A E ET++PL Q
Sbjct: 758 QKEDILKHRVVVVTLN--TSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNT 815
Query: 2382 KVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHED-------AHMLDTQYRMHEGICAF 2434
++VL GDH QL P V +E + L SL +R +E +L YR HE I +
Sbjct: 816 RIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINY 875
Query: 2435 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 2494
S FY+ KL S A K+ P+ F +G + E N + N
Sbjct: 876 TSELFYEGKLMA--------SGKQPAHKDFYPLTFFTARGED------VQEKNSTAFYNN 921
Query: 2495 EEVAEVVRITKQL-----TLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT 2549
EV EVV ++L ++ I V+TPY Q I LR++ ++ V V +
Sbjct: 922 AEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVL 981
Query: 2550 KSQGSEWRYVLVSTVRTCAKSDLDQRPTK--------SWLKKFLGFVVDPNQVNVAVTRA 2601
QG ++R + +STVRT Q P K S GF+ + +N A+TRA
Sbjct: 982 NVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRA 1041
Query: 2602 QEGLCLIGDHLLL----RCCPLWRSLLDFCEAQQTL 2633
Q + ++GD + L RC W + C +L
Sbjct: 1042 QSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1077
>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
Length = 1118
Score = 184 bits (467), Expect = 1e-45
Identities = 157/514 (30%), Positives = 239/514 (46%), Gaps = 86/514 (16%)
Query: 2134 IPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHK 2193
+P RF + G LN SQ AV+ L++P ++IQGPPGTGKT+ IV+ +
Sbjct: 459 LPKRFTAQ-------GLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR 511
Query: 2194 SNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASE 2253
Q GP +L C PSN +VD L + + LK +R+ ++ EA +
Sbjct: 512 ------QGNGP-----------VLVCAPSNIAVDQLTEKI-HQTGLKVVRLCAKSREAID 553
Query: 2254 FPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSR 2313
PV + LH++IR + + K + + GEL S
Sbjct: 554 SPVS----------------------FLALHNQIRNMDSMPELQ-KLQQLKDETGELSSA 590
Query: 2314 EDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIP 2373
++ Y+ + A + L +VI CTC A L + R IL+DE+ ATEPE ++P
Sbjct: 591 DEKR-YRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP 649
Query: 2374 LVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHE---DAHMLDTQYRMHEG 2430
+V A++++L+GDH QL PVV ++ GL +SLFER L QYRMH
Sbjct: 650 VVL--GAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPA 707
Query: 2431 ICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG----KESCPVIFGHVQGHERSLLVSTDEG 2486
+ AFPS FY+ L+ G+ V + P+ F QG E T
Sbjct: 708 LSAFPSNIFYEGSLQN--GVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765
Query: 2487 NENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQAS------EISKALRREGI 2540
N AN+E++ TK L G +P I ++TPY Q S + S +L +
Sbjct: 766 NRTEAANVEKIT-----TKLLKAG--AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLY 818
Query: 2541 AGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTR 2600
V ++S+ QG E ++++S VR + GF+ DP ++NVA+TR
Sbjct: 819 QEVEIASVDAFQGREKDFIILSCVRANEHQGI-------------GFLNDPRRLNVALTR 865
Query: 2601 AQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
A+ G+ ++G+ L PLW LL++ + Q+ LV
Sbjct: 866 ARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLV 899
Score = 79.3 bits (194), Expect = 5e-14
Identities = 120/454 (26%), Positives = 175/454 (38%), Gaps = 67/454 (14%)
Query: 501 CALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLIYGPFGTGKTYTLAMASLE 560
C LP+ ++ L N Q AV + + P LI GP GTGKT T A
Sbjct: 457 CQLPKRFTAQGLPDLNHSQVYAVKTVL--------QRPLSLIQGPPGTGKTVTSATIVYH 508
Query: 561 VIRRPETKVLICTHTNSAAD-----------------IYIREYFHSHVS--GGHPEATPL 601
+ R+ VL+C +N A D RE S VS H + +
Sbjct: 509 LARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNM 568
Query: 602 RVMYTDRPLSQTDPVTLQYCCLTDDR-QAFRPPTRAELARHR-VVVTTTSQARELRVPVG 659
M + L Q T + + R +A + EL + V+ T A + R+
Sbjct: 569 DSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKM 628
Query: 660 FFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAA-EHTLLH 718
F ILIDE+ Q E E + P+ + +L+L GDH Q+ P + A+A +L
Sbjct: 629 QFRSILIDESTQATEPECMVPVVLGA--KQLILVGDHCQLGPVVMCKKAAKAGLSQSLFE 686
Query: 719 RLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAK-GNPIHARGKVP----- 772
RL + R RL YR A+ +F S FY N + A +V
Sbjct: 687 RLVVL-------GIRPIRL--QVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDF 737
Query: 773 --PHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCI 830
P P P+ F G + S S+LN E A V E T G + +
Sbjct: 738 QWPQP-DKPMFFYVTQGQEEIASSGTSYLNRTEAANV-----EKITTKLLKAGAKPDQIG 791
Query: 831 CVVSHGAQVSALRQ------ELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSP 884
+ + Q S L Q L + +V + S + GR+ ++LS V +
Sbjct: 792 IITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEH---- 847
Query: 885 GALAPEFFTDARVLNTVLTRAQSQLVVVGDAVAL 918
F D R LN LTRA+ +++VG+ AL
Sbjct: 848 --QGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 879
>gi|14251207 MOV10-like 1 [Homo sapiens]
Length = 1211
Score = 139 bits (351), Expect = 3e-32
Identities = 142/467 (30%), Positives = 217/467 (46%), Gaps = 47/467 (10%)
Query: 516 NRKQELAVALIAGWGPGDGRRVPPLLIYGPFGTGKTYTLAMASLEV-IRRPETKVLICTH 574
N Q+LAV I GD R +P +L +GP GTGKT T+ A L+V P++++L+C
Sbjct: 746 NENQKLAVKRILS---GDCRPLPYIL-FGPPGTGKTVTIIEAVLQVHFALPDSRILVCAP 801
Query: 575 TNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 634
+NSAAD+ S V AT +RV T R YC +D
Sbjct: 802 SNSAADLVCLRLHESKVL---QPATMVRVNATCRFEEIVIDAVKPYCRDGEDIW------ 852
Query: 635 RAELARHRVVVTTTSQAR---ELRVPVGFFSHILIDEAAQMLECEALTPLAYASH-GTRL 690
+ +R R+++TT S + ++ V VG F+H+ +DEA Q E E L PL S ++
Sbjct: 853 --KASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQI 910
Query: 691 VLAGDHMQVTPRLFS-VARARAAEHTLLHRLFL--CYQQE--------THEVARQSRLVF 739
VLAGD MQ+ P + S +A A + L RL YQ++ H ++LV
Sbjct: 911 VLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLV- 969
Query: 740 HENYRCTDAIVSFISRHFYVAK----GNPIHARG-----KVPPHPRHYPLMFCHVAGSPD 790
+NYR +A++ SR FY + +P K+P + +PL+F V GS
Sbjct: 970 -KNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPK--KGFPLIFHGVRGSEA 1026
Query: 791 RDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRD 850
R+ SW N AE QV+ ++ S + I + QV +R LR D
Sbjct: 1027 REGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVI--TPYRKQVEKIRILLRNVD 1084
Query: 851 LGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLV 910
L + VGS E G+++ V+++STV + + F ++++ N +TR ++ L+
Sbjct: 1085 LMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLI 1144
Query: 911 VVGDAVALCSFGACGKLWESFIRECVERHSVCPEGL-SMEQVEQGVA 956
V+G+ L G L E I V P L S++ +GVA
Sbjct: 1145 VLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVA 1191
Score = 131 bits (329), Expect = 1e-29
Identities = 145/507 (28%), Positives = 215/507 (42%), Gaps = 120/507 (23%)
Query: 2153 LNPSQNVAVREALE---KPFT-VIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 2208
LN +Q +AV+ L +P ++ GPPGTGKT+ + V H +
Sbjct: 745 LNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFA-------------- 790
Query: 2209 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 2268
L IL C PSN + D++ LR E K L+ P V
Sbjct: 791 --LPDSRILVCAPSNSAADLVC---LRLHESKVLQ-----------PATMV--------- 825
Query: 2269 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 2328
R N + R + A PY + ED+ W+A +
Sbjct: 826 ----RVNATCR---FEEIVIDAVKPYCRD---------------GEDI-------WKASR 856
Query: 2329 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPL-VQFPQAEKVV 2384
F +I+ TCS + +++ + VDEAG A+EPE LIPL + + ++V
Sbjct: 857 FR-----IIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIV 911
Query: 2385 LLGDHKQLRPVVKNERLQNLGLDRSLFER------YHED--------AH------MLDTQ 2424
L GD QL PV+K+ GL+ S ER Y D AH L
Sbjct: 912 LAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKN 971
Query: 2425 YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLG--HAGKESCPVIFGHVQGHERSLLVS 2482
YR HE + PS FY +L+ S+LG K+ P+IF V+G E
Sbjct: 972 YRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAR---- 1027
Query: 2483 TDEGNENSKANLEEVAEVVRITKQL--TLGRTVEPQDIAVLTPYNAQASEISKALRREGI 2540
EG S N E +V+R L ++ V DI V+TPY Q +I LR +
Sbjct: 1028 --EGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDL 1085
Query: 2541 AGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTR 2600
+ V S+ + QG E+ +++STVR+ D R FLGF+ + + NVA+TR
Sbjct: 1086 MDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDR-------YFLGFLSNSKRFNVAITR 1138
Query: 2601 AQEGLCLIGD-HLLLRCCPLWRSLLDF 2626
+ L ++G+ H+L+R P + +LL++
Sbjct: 1139 PKALLIVLGNPHVLVR-DPCFGALLEY 1164
>gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
isoform 1 [Homo sapiens]
Length = 1054
Score = 130 bits (326), Expect = 2e-29
Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)
Query: 1155 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 1214
I + G + GD V+V+LL P+ +GR + + + + A P
Sbjct: 277 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 326
Query: 1215 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 1258
+P G V I +D PS+ + S K R+ ++ + AE
Sbjct: 327 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 385
Query: 1259 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 1318
V+I W YP G VL E + + +E S+ V P +A + +
Sbjct: 386 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 445
Query: 1319 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 1372
+ +V+ E R + L F++DP+G ++DD LSVR L E+ VHI
Sbjct: 446 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 505
Query: 1373 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 1432
DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+
Sbjct: 506 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 564
Query: 1433 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 1484
++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++
Sbjct: 565 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 624
Query: 1485 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534
V A + + R R + D C Q D+ + H ++ + ++ +
Sbjct: 625 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 679
Query: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594
VAE ++ V W+ P +AL +H PP
Sbjct: 680 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 714
Query: 1595 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1647
L K F T+ + + D L +D H P + R + +A
Sbjct: 715 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 774
Query: 1648 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1701
G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S +
Sbjct: 775 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 831
Query: 1702 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1734
D++ LC+ + ++ AQ Q+++ L + K
Sbjct: 832 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 864
>gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like isoform
2 [Homo sapiens]
Length = 971
Score = 130 bits (326), Expect = 2e-29
Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)
Query: 1155 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 1214
I + G + GD V+V+LL P+ +GR + + + + A P
Sbjct: 194 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 243
Query: 1215 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 1258
+P G V I +D PS+ + S K R+ ++ + AE
Sbjct: 244 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 302
Query: 1259 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 1318
V+I W YP G VL E + + +E S+ V P +A + +
Sbjct: 303 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 362
Query: 1319 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 1372
+ +V+ E R + L F++DP+G ++DD LSVR L E+ VHI
Sbjct: 363 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 422
Query: 1373 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 1432
DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+
Sbjct: 423 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 481
Query: 1433 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 1484
++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++
Sbjct: 482 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 541
Query: 1485 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534
V A + + R R + D C Q D+ + H ++ + ++ +
Sbjct: 542 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 596
Query: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594
VAE ++ V W+ P +AL +H PP
Sbjct: 597 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 631
Query: 1595 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1647
L K F T+ + + D L +D H P + R + +A
Sbjct: 632 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 691
Query: 1648 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1701
G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S +
Sbjct: 692 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 748
Query: 1702 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1734
D++ LC+ + ++ AQ Q+++ L + K
Sbjct: 749 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 781
>gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
Length = 928
Score = 119 bits (297), Expect = 5e-26
Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)
Query: 1189 GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 1248
GRV+G++KR W P G ++K + E S+ +++ R+
Sbjct: 313 GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 351
Query: 1249 RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 1308
R+ +E A R V I W + YP G L + E +L LE+ +
Sbjct: 352 RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 411
Query: 1309 PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 1367
P QA ++ + + + + RED R +VDP G ++DDAL R+L E
Sbjct: 412 QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 471
Query: 1368 VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 1427
V VHI DV+ F+ LD E+ R+G Y + + M+P L ++ SL DRLA
Sbjct: 472 VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 530
Query: 1428 SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 1487
S M + LK+ +F SV+ S L+Y EA+ I + D + +
Sbjct: 531 SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 581
Query: 1488 AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 1533
+++L++ R+ D P + T R + MV+E+M+ N
Sbjct: 582 GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 641
Query: 1534 RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1593
VA K + E+ + L H +PP
Sbjct: 642 ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 666
Query: 1594 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1651
+ +L + +T + + + + P+L R L A C+
Sbjct: 667 SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 726
Query: 1652 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1708
G HY L YT TSPIRRY DV++ R + +A+G + D + +C+
Sbjct: 727 -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 785
Query: 1709 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1736
+ +H +AQ QR + + H + K++
Sbjct: 786 NLNFRHKMAQYAQRASVAFHTQLFFKSK 813
>gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]
Length = 958
Score = 119 bits (297), Expect = 5e-26
Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)
Query: 1189 GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 1248
GRV+G++KR W P G ++K + E S+ +++ R+
Sbjct: 343 GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 381
Query: 1249 RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 1308
R+ +E A R V I W + YP G L + E +L LE+ +
Sbjct: 382 RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 441
Query: 1309 PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 1367
P QA ++ + + + + RED R +VDP G ++DDAL R+L E
Sbjct: 442 QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 501
Query: 1368 VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 1427
V VHI DV+ F+ LD E+ R+G Y + + M+P L ++ SL DRLA
Sbjct: 502 VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 560
Query: 1428 SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 1487
S M + LK+ +F SV+ S L+Y EA+ I + D + +
Sbjct: 561 SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 611
Query: 1488 AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 1533
+++L++ R+ D P + T R + MV+E+M+ N
Sbjct: 612 GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 671
Query: 1534 RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1593
VA K + E+ + L H +PP
Sbjct: 672 ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 696
Query: 1594 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1651
+ +L + +T + + + + P+L R L A C+
Sbjct: 697 SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 756
Query: 1652 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1708
G HY L YT TSPIRRY DV++ R + +A+G + D + +C+
Sbjct: 757 -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 815
Query: 1709 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1736
+ +H +AQ QR + + H + K++
Sbjct: 816 NLNFRHKMAQYAQRASVAFHTQLFFKSK 843
>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
Length = 1003
Score = 117 bits (294), Expect = 1e-25
Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)
Query: 2154 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 2208
NP Q A+R + P+ +I GPPGTGKT+ + + +QV
Sbjct: 500 NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542
Query: 2209 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 2268
K L IL C PSN D+L L R+ L P +Y A + + +R
Sbjct: 543 KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588
Query: 2269 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 2328
P + +P + ++GE ++ A+K
Sbjct: 589 PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611
Query: 2329 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 2382
+L + V++ T A SA I I +DEAG EPE+L+ + + ++
Sbjct: 612 -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670
Query: 2383 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 2424
+VL GD +QL PV+++ Q GL SL ER Y + D Q
Sbjct: 671 PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730
Query: 2425 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 2481
YR H I P+ +Y+ +L+ + AG ++ P+IF V G +
Sbjct: 731 NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787
Query: 2482 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 2535
EGN S N EE A V K L + + P+ + V++PY Q +I +
Sbjct: 788 ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844
Query: 2536 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2584
+ + I + V S+ + QG E +L+STVR+ + DLD
Sbjct: 845 TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895
Query: 2585 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2628
LGF+ +P + NVAVTRA+ L ++G+ LLL P W+ L+FC+
Sbjct: 896 LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939
Score = 114 bits (284), Expect = 2e-24
Identities = 122/449 (27%), Positives = 205/449 (45%), Gaps = 57/449 (12%)
Query: 536 RVPPLLIYGPFGTGKTYTLAMASLEVIRR-PETKVLICTHTNSAADIYIREYFHSHVSGG 594
R P +I+GP GTGKT TL A +V++ P+ +L C +NS AD+ +
Sbjct: 516 RPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL------RV 569
Query: 595 HPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA-FRPPTRAELARHRVVVTTTSQARE 653
H ++ R++ R + P ++ CC D ++ + P + +L +RV++TT A
Sbjct: 570 HLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGR 628
Query: 654 L---RVPVGFFSHILIDEAAQMLECEALTPLA-------YASHGTRLVLAGDHMQVTPRL 703
L + P+ F+HI IDEA +E E+L +A G +LVLAGD Q+ P L
Sbjct: 629 LVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVL 688
Query: 704 FS-VARARAAEHTLLHRLFL---CYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYV 759
S + + ++LL RL Y++ Q NYR I+ ++ +Y
Sbjct: 689 RSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYE 748
Query: 760 AKGNPIHARGKVPPHPRH----------YPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE 809
+ + A V R +P++F V G +R+ + S+ N E A V
Sbjct: 749 GE---LQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTS 805
Query: 810 KVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVSALR-------QELR-RRDLGQVSVG 857
++ PS G+ + R + V+S + QV +R +ELR D+ + VG
Sbjct: 806 YLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVG 863
Query: 858 SFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEFFTDARVLNTVLTRAQSQLVVVGDAV 916
S E G++ V+++STV + QS + F + + N +TRA++ L++VG+ +
Sbjct: 864 SVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPL 923
Query: 917 ALCSFGACGKLWESFIRECVER--HSVCP 943
L W+ F+ C E ++ CP
Sbjct: 924 LL----GHDPDWKVFLEFCKENGGYTGCP 948
>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
Length = 1003
Score = 117 bits (294), Expect = 1e-25
Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)
Query: 2154 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 2208
NP Q A+R + P+ +I GPPGTGKT+ + + +QV
Sbjct: 500 NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542
Query: 2209 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 2268
K L IL C PSN D+L L R+ L P +Y A + + +R
Sbjct: 543 KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588
Query: 2269 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 2328
P + +P + ++GE ++ A+K
Sbjct: 589 PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611
Query: 2329 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 2382
+L + V++ T A SA I I +DEAG EPE+L+ + + ++
Sbjct: 612 -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670
Query: 2383 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 2424
+VL GD +QL PV+++ Q GL SL ER Y + D Q
Sbjct: 671 PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730
Query: 2425 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 2481
YR H I P+ +Y+ +L+ + AG ++ P+IF V G +
Sbjct: 731 NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787
Query: 2482 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 2535
EGN S N EE A V K L + + P+ + V++PY Q +I +
Sbjct: 788 ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844
Query: 2536 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2584
+ + I + V S+ + QG E +L+STVR+ + DLD
Sbjct: 845 TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895
Query: 2585 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2628
LGF+ +P + NVAVTRA+ L ++G+ LLL P W+ L+FC+
Sbjct: 896 LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939
Score = 114 bits (284), Expect = 2e-24
Identities = 122/449 (27%), Positives = 205/449 (45%), Gaps = 57/449 (12%)
Query: 536 RVPPLLIYGPFGTGKTYTLAMASLEVIRR-PETKVLICTHTNSAADIYIREYFHSHVSGG 594
R P +I+GP GTGKT TL A +V++ P+ +L C +NS AD+ +
Sbjct: 516 RPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL------RV 569
Query: 595 HPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA-FRPPTRAELARHRVVVTTTSQARE 653
H ++ R++ R + P ++ CC D ++ + P + +L +RV++TT A
Sbjct: 570 HLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGR 628
Query: 654 L---RVPVGFFSHILIDEAAQMLECEALTPLA-------YASHGTRLVLAGDHMQVTPRL 703
L + P+ F+HI IDEA +E E+L +A G +LVLAGD Q+ P L
Sbjct: 629 LVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVL 688
Query: 704 FS-VARARAAEHTLLHRLFL---CYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYV 759
S + + ++LL RL Y++ Q NYR I+ ++ +Y
Sbjct: 689 RSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYE 748
Query: 760 AKGNPIHARGKVPPHPRH----------YPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE 809
+ + A V R +P++F V G +R+ + S+ N E A V
Sbjct: 749 GE---LQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTS 805
Query: 810 KVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVSALR-------QELR-RRDLGQVSVG 857
++ PS G+ + R + V+S + QV +R +ELR D+ + VG
Sbjct: 806 YLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVG 863
Query: 858 SFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEFFTDARVLNTVLTRAQSQLVVVGDAV 916
S E G++ V+++STV + QS + F + + N +TRA++ L++VG+ +
Sbjct: 864 SVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPL 923
Query: 917 ALCSFGACGKLWESFIRECVER--HSVCP 943
L W+ F+ C E ++ CP
Sbjct: 924 LL----GHDPDWKVFLEFCKENGGYTGCP 948
>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
Length = 993
Score = 115 bits (289), Expect = 4e-25
Identities = 146/547 (26%), Positives = 218/547 (39%), Gaps = 113/547 (20%)
Query: 2113 ASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTV 2171
AS L+ + GR P P + P F L+ SQ AV AL +K +
Sbjct: 163 ASSLI-EVLFGRSAPSPASEIHPLTFFNTC----------LDTSQKEAVLFALSQKELAI 211
Query: 2172 IQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAG 2231
I GPPGTGKT + I+ K G +L C PSN +VD L
Sbjct: 212 IHGPPGTGKTTTVVEIILQAVKQ------------------GLKVLCCAPSNIAVDNL-- 251
Query: 2232 LLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAP 2291
+ R+ L R+ R G P + L SI H
Sbjct: 252 --VERLALCKQRIL------------------------RLGHPARLLESIQQHSLDAVLA 285
Query: 2292 NPYSSEIKAFDTRLQRGELFS--------------REDLVWYKKVLWEARKF----ELDR 2333
S++I A D R ++F R ++ +K L E + L
Sbjct: 286 RSDSAQIVA-DIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTS 344
Query: 2334 HEVILCT-CSCAASASLKILDVRQ---ILVDEAGMATEPETLIPLVQFPQAEKVVLLGDH 2389
V+L T +A LK+L +++DE A E IPL++ A K +L GDH
Sbjct: 345 ANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLK---ARKCILAGDH 401
Query: 2390 KQLRPVVKNERLQNLGLDRSLFERYHED-----AHMLDTQYRMHEGICAFPSVAFYKSKL 2444
KQL P + + GL SL ER E+ L QYRMH+ I + S Y +L
Sbjct: 402 KQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQL 461
Query: 2445 KTWQG-----LRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAE 2499
LR P V + P++ G L +E +E SK N EV
Sbjct: 462 TAHSSVARHLLRDLPGVAA-TEETGVPLLLVDTAG---CGLFELEEEDEQSKGNPGEV-R 516
Query: 2500 VVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYV 2559
+V + Q + V +DIAV++PYN Q + ++L + + S+ QG E V
Sbjct: 517 LVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAV 575
Query: 2560 LVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPL 2619
++S VR+ K + +GF+ + ++NVAVTRA+ + +I D +
Sbjct: 576 ILSFVRSNRKGE-------------VGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF 622
Query: 2620 WRSLLDF 2626
++L+++
Sbjct: 623 LKTLVEY 629
Score = 67.0 bits (162), Expect = 2e-10
Identities = 130/570 (22%), Positives = 211/570 (37%), Gaps = 105/570 (18%)
Query: 541 LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYF---HSHVSGGHPE 597
+I+GP GTGKT T+ L+ +++ KVL C +N A D + + GHP
Sbjct: 211 IIHGPPGTGKTTTVVEIILQAVKQG-LKVLCCAPSNIAVDNLVERLALCKQRILRLGHPA 269
Query: 598 AT--PLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHR------------- 642
++ D L+++D + D Q F + + R +
Sbjct: 270 RLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKE 329
Query: 643 ------------------VVVTTTSQARE---LRVPVGFFSHILIDEAAQMLECEALTPL 681
V+ T T + + +P +F ++IDE AQ LE PL
Sbjct: 330 LKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL 389
Query: 682 AYASHGTRLVLAGDHMQVTPRLFSVARARAA-EHTLLHRLFLCYQQETHEVARQSRLVFH 740
A + +LAGDH Q+ P S A A +L+ RL E +
Sbjct: 390 LKAR---KCILAGDHKQLPPTTVSHKAALAGLSLSLMERL-------AEEYGARVVRTLT 439
Query: 741 ENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPH------------PRHYPLMFCHVAGS 788
YR AI+ + S Y+ + + A V H PL+ AG
Sbjct: 440 VQYRMHQAIMRWASDTMYLGQ---LTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGC 496
Query: 789 ---PDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGAQVSALRQ 844
+ S N E+ V +Q + G R I VVS + QV LRQ
Sbjct: 497 GLFELEEEDEQSKGNPGEVRLVSLHIQALVD------AGVPARDIAVVSPYNLQVDLLRQ 550
Query: 845 ELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTR 904
L R ++ + S + GR+ V+LS V + + G + F + R +N +TR
Sbjct: 551 SLVHRH-PELEIKSVDGFQGREKEAVILSFVRSNRK----GEVG--FLAEDRRINVAVTR 603
Query: 905 AQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPR 964
A+ + V+ D+ + + L E F + R + E ++ V P
Sbjct: 604 ARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVR-------TAFEYLDDIV------PEN 650
Query: 965 GTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAA 1024
+ + G+ AA +P G + T + E G EA +PA + ++ A+ A
Sbjct: 651 YSHENSQGSSHAATKPQGPATSTR----TGSQRQEGGQEAAAPARQGRKKPAGKSLASEA 706
Query: 1025 PAGDAVKEDVVPGACAAGAAAAAGVESTEA 1054
P+ ++ G G + GV+ A
Sbjct: 707 PSQPSLN-----GGSPEGVESQDGVDHFRA 731
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 109 bits (273), Expect = 3e-23
Identities = 135/530 (25%), Positives = 229/530 (43%), Gaps = 107/530 (20%)
Query: 2171 VIQGPPGTGK--TIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDV 2228
+I GPPGTGK TIVGL + + Q + ++ +L C PSN +VD
Sbjct: 1960 LIHGPPGTGKSKTIVGL----LYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDE 2015
Query: 2229 LAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLR---SITLHH 2285
L ++++ L+ + E+ + + P+ G L+R P + ++ L+ ++H
Sbjct: 2016 L----MKKIILE----FKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNH 2067
Query: 2286 RIRQAPNPYSSEIKAFDTR-----------------------LQRGELFS--------RE 2314
R+++ S ++A R +QR EL R+
Sbjct: 2068 RMKKE---LPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQ 2124
Query: 2315 DLVW-YKKVLWEARKFE----LDRHEVILCTCSCAASASLKILDVRQ-------ILVDEA 2362
+L K+V +K + L+ H +I CT S + L+ Q ++VDEA
Sbjct: 2125 ELASKIKEVQGRPQKTQSIIILESH-IICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 2183
Query: 2363 GMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERY----HEDA 2418
G + E ETL PL+ + K++L+GD KQL P V + + Q G D+S+ R+ E+
Sbjct: 2184 GQSCEIETLTPLIH--RCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENV 2241
Query: 2419 H----------MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCP-V 2467
L QYRMH IC FPS Y LKT R+ ++ + P +
Sbjct: 2242 EHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKT---NRQTEAIRCSSDWPFQPYL 2298
Query: 2468 IFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGR-TVEPQDIAVLTPYNA 2526
+F G ER + +S N++E+ V+ I K + R V ++I ++T Y A
Sbjct: 2299 VFDVGDGSERR--------DNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKA 2350
Query: 2527 QASEISKALRRE--GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF 2584
Q + I K L +E V ++ QG + V+V+ VR + ++
Sbjct: 2351 QKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRA------------NSIQGS 2398
Query: 2585 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
+GF+ ++NV +TRA+ L ++G L W L+ + + ++
Sbjct: 2399 IGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAII 2448
Score = 55.5 bits (132), Expect = 7e-07
Identities = 71/290 (24%), Positives = 126/290 (43%), Gaps = 26/290 (8%)
Query: 661 FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSV-ARARAAEHTLLHR 719
FS +++DEA Q E E LTPL + + +L+L GD Q+ P + S+ A+ + +++ R
Sbjct: 2175 FSCVIVDEAGQSCEIETLTPLIHRCN--KLILVGDPKQLPPTVISMKAQEYGYDQSMMAR 2232
Query: 720 LFLCYQQ--ETHEVARQSRLVFHENYRCTDAIVSFISRHFY---VAKGNPIHARGKVPPH 774
++ E + ++R L YR I F S + Y + A
Sbjct: 2233 FCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDW 2292
Query: 775 PRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS 834
P L+F GS RD S++N+ EI V+E ++ + R I +++
Sbjct: 2293 PFQPYLVFDVGDGSERRDND--SYINVQEIKLVMEIIKLIKDKRKDV----SFRNIGIIT 2346
Query: 835 H-GAQVSALRQELRRR--DLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEF 891
H AQ + ++++L + G V + + GRQ V+++ V S G F
Sbjct: 2347 HYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-----F 2401
Query: 892 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSV 941
+ LN +TRA+ L ++G L + W I++ +R ++
Sbjct: 2402 LASLQRLNVTITRAKYSLFILGHLRTLME----NQHWNQLIQDAQKRGAI 2447
>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
[Homo sapiens]
Length = 885
Score = 102 bits (254), Expect = 5e-21
Identities = 139/519 (26%), Positives = 215/519 (41%), Gaps = 76/519 (14%)
Query: 1264 LFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKY 1323
LF +IV W++ + LG + + L +A E + EY + + + Q
Sbjct: 300 LFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGL 359
Query: 1324 HTELG-RVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHITDVASFVPR 1381
+ +R D R FT+DP A +LDDALS + L +V VHI DV+ FVP
Sbjct: 360 PWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPE 419
Query: 1382 DGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLK 1441
LD A + + Y ++ VPMLP LC+++ SL P D+L S+ T+ G++
Sbjct: 420 GSDLDKVAAERATSVYLV-QKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTL-TPEGKIL 477
Query: 1442 SLRFAPSVVQSDRQLSYEEAEEVIRQ--HPGAGRELPA-----RLDSVDACVVAACYFSR 1494
F ++++S +LSYE A+ +I +ELP + V V+ ++
Sbjct: 478 DEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAK 537
Query: 1495 LLRRHR-----LRSDCFYEQPDEDGTLGF-RAAHIMVKEYMIQFNRLVAEFLVGSECTRT 1548
LR+ R LR D D G + HI EY + N+LV EF++ +
Sbjct: 538 QLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCHIY--EYR-ESNKLVEEFMLLAN---- 590
Query: 1549 VTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQF 1608
A+ K P L H PP TR+ L V+F
Sbjct: 591 ---------------MAVAHKIHRAFPEQALLRRH------PPPQTRM-----LSDLVEF 624
Query: 1609 AARTQDYEQM---VDLVTTDDMHPFLAPAGRDLRKALERSAF--GRCARGHQQ------- 1656
+QM VD + ++ L D + +L R C+R Q
Sbjct: 625 C------DQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG 678
Query: 1657 ------QGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD-IDGLCQA 1709
Q HY+L V YT TSPIRR+ DV++ R + ALG+ A D +
Sbjct: 679 LLQDPAQFRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADH 738
Query: 1710 FSLQHALAQSYQRRARSLHLAVQLK-AQPLDKLGFVVDV 1747
+ + ++ Q + SL AV +K + PL+ V+ +
Sbjct: 739 CNDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGI 777
>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
Length = 1146
Score = 90.1 bits (222), Expect = 3e-17
Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%)
Query: 2311 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 2367
F+ +++ K + A EL ++I+ T + S KI D +VDEA ++
Sbjct: 798 FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855
Query: 2368 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 2424
P L PL + + VL+GDH+QL P+V N + LG+ SLF+R ++ L Q
Sbjct: 856 PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912
Query: 2425 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 2472
YRM+ I + + Y+ KL+ LR V +A P + G
Sbjct: 913 YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972
Query: 2473 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 2526
+ + ++TD + + +N+ E +V +T + + P DI ++ PY
Sbjct: 973 EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031
Query: 2527 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2586
Q I+ L R I V V+++ K QG + VLVS VR+ + + K W
Sbjct: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083
Query: 2587 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
++NVA+TRA+ L L+G L C P LL+ +++ ++
Sbjct: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126
Score = 55.8 bits (133), Expect = 5e-07
Identities = 88/413 (21%), Positives = 163/413 (39%), Gaps = 54/413 (13%)
Query: 541 LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP 600
LI G GTGKT T+ + ++ VL+ ++T+SA D + + +
Sbjct: 731 LIVGMPGTGKTTTICTL-VRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGF------- 782
Query: 601 LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPV-- 658
LR+ + T Q C + ++ EL +++V TT + P+
Sbjct: 783 LRLGQIQKVHPAIQQFTEQEICRSKSIKSLA--LLEELYNSQLIVATTCMG--INHPIFS 838
Query: 659 -GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTL 716
F ++DEA+Q+ + L PL ++ R VL GDH Q+ P + + ARA +L
Sbjct: 839 RKIFDFCIVDEASQISQPICLGPLFFSR---RFVLVGDHQQLPPLVLNREARALGMSESL 895
Query: 717 LHR----------LFLCYQQETHEVARQSRLVFHENYRC-----TDAIVSF-------IS 754
R L + Y+ + ++ ++L + C +A+++ +
Sbjct: 896 FKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLE 955
Query: 755 RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 814
FY + G P + P+ F + P + + ++ V E
Sbjct: 956 LEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPAPEQ-----VEKGGVSNVTEAKLIV 1007
Query: 815 YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 874
+ T G I +++ Q + +L R +G V V + + GR +V++S
Sbjct: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067
Query: 875 VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKL 927
V + + E D R LN +TRA+ +L+++G +L + KL
Sbjct: 1068 VRS-----NKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKL 1115
>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
Length = 1918
Score = 79.0 bits (193), Expect = 6e-14
Identities = 84/300 (28%), Positives = 135/300 (45%), Gaps = 37/300 (12%)
Query: 2349 LKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERL-QNLGLD 2407
L+ ++ R ++V+EA E T+ L + + ++L+GDH+QLRP L +N L+
Sbjct: 995 LQKVEPRIVIVEEAAEVLEAHTIATLSK--ACQHLILIGDHQQLRPSANVYDLAKNFNLE 1052
Query: 2408 RSLFERYHE---DAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKE- 2463
SLFER + L+ Q+RM I + Y Q L PSVL + +
Sbjct: 1053 VSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIY-------QDLENHPSVLKYEKIKG 1105
Query: 2464 -SCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLT 2522
S + F E+ + EG S N E VV + K L + P I +LT
Sbjct: 1106 VSSNLFFVEHNFPEQEI----QEGK--SHQNQHEAHFVVELCKYF-LCQEYLPSQITILT 1158
Query: 2523 PYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLK 2582
Y Q + K + + AGV V + K QG E +L+S VR+ +
Sbjct: 1159 TYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGK----------- 1207
Query: 2583 KFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVC 2642
+GF+ N++ VA++RA++G+ IG+ +L PLW ++ + P +R+C
Sbjct: 1208 --VGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGP--MLRLC 1263
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/37 (59%), Positives = 27/37 (72%)
Query: 2152 KLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIV 2188
KL+ SQ A++ AL + +IQGPPGTGKT VGL IV
Sbjct: 597 KLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIV 633
Score = 34.3 bits (77), Expect = 1.7
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 4/59 (6%)
Query: 664 ILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTP--RLFSVARARAAEHTLLHRL 720
++++EAA++LE + L+ A L+L GDH Q+ P ++ +A+ E +L RL
Sbjct: 1003 VIVEEAAEVLEAHTIATLSKACQ--HLILIGDHQQLRPSANVYDLAKNFNLEVSLFERL 1059
>gi|38788372 aquarius [Homo sapiens]
Length = 1485
Score = 59.3 bits (142), Expect = 5e-08
Identities = 79/304 (25%), Positives = 128/304 (42%), Gaps = 44/304 (14%)
Query: 2335 EVILCTCSCAASASLKILDVR----QILVDEAGMATEPETLIPLVQ------FPQAEKVV 2384
++I TC+ AA ++ + IL++EA E ET IPL+ F + ++ +
Sbjct: 1033 KIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWI 1092
Query: 2385 LLGDHKQLRPVVKNERLQNL-GLDRSLFERYHE---DAHMLDTQYRMHEGICAFPSVAFY 2440
++GDH QL PV+KN Q +++SLF R+ LD Q R +C Y
Sbjct: 1093 MIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLC-----NLY 1147
Query: 2441 KSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEV 2500
+ K L + + + + + E V E N NL E V
Sbjct: 1148 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYV 1207
Query: 2501 VRITKQLTLGRTVEPQD-IAVLTPYNAQASEISKALRR----EGIAG--VAVSSITKSQG 2553
V + + L P D I++LT YN Q I + R + G V+++ + QG
Sbjct: 1208 VALFMYMCL--LGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQG 1265
Query: 2554 SEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLL 2613
+ Y+L+S VRT A +G + D ++ VA++RA+ GL + L
Sbjct: 1266 QQNDYILLSLVRTRA----------------VGHLRDVRRLVVAMSRARLGLYIFARVSL 1309
Query: 2614 LRCC 2617
+ C
Sbjct: 1310 FQNC 1313
Score = 34.7 bits (78), Expect = 1.3
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 2156 SQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQ 2198
+Q A+R ++ T++ GPPGTGKT V + I+ + + EQ
Sbjct: 805 TQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQ 847
>gi|27414497 zinc finger CCCH-type containing 7A [Homo sapiens]
Length = 971
Score = 53.5 bits (127), Expect = 3e-06
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 41 YCPACLVTCHSQEAFENHCASSEHAQMVAF--DQALPWEHRSPPPGLSKFELCPK--PDL 96
+C C C+S++ ++ H +S +H + V D W+HR P F +C +
Sbjct: 858 HCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPT---GYFSICDRYMNGT 914
Query: 97 CEYGDACTKAHSAQELQEWVRRTQAVELRGQAAWQDGLVPYQERLLAEY 145
C G++C AH EL EW R A++++ A +D L+ + +Y
Sbjct: 915 CPEGNSCKFAHGNAELHEWEERRDALKMKLNKARKDHLIGPNDNDFGKY 963
>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
Length = 977
Score = 46.2 bits (108), Expect = 4e-04
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 41 YCPACLVTCHSQEAFENHCASSEHAQMV--AFDQALPWEHRSPPPGLSKFELCP---KPD 95
+C C +S++ ++ H S +H + V + A W R P + +F LC K
Sbjct: 843 HCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSDSDASGWAFRFP---MGEFRLCDRLQKGK 899
Query: 96 LCEYGDACTKAHSAQELQEWVRRTQAVELRGQAAWQDGLV 135
C GD C AH +EL EW+ R + ++ + A +D L+
Sbjct: 900 ACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLL 939
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 37.4 bits (85), Expect = 0.20
Identities = 58/209 (27%), Positives = 83/209 (39%), Gaps = 26/209 (12%)
Query: 985 AEEQAAV---VTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAA 1041
A E+A + + A KA G S + + A A AG + GA A
Sbjct: 1865 AGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGA-EA 1923
Query: 1042 GAAAAAGVESTEAEDAEADFWPWDGELNADDAIL---RELLDESQKVMVTVGEDGLLDTV 1098
GA A AG + ++ A W WDG+ ++ L E ES + VGED L
Sbjct: 1924 GAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDEL---- 1979
Query: 1099 ARPESLQQARLYENLPPAALRKLLHAEPER---YRHCSFVPETFERASAIPLDDAS-SGP 1154
+R S ++ +LR L AE E +R S +FE + D+ S
Sbjct: 1980 SRESS-------PDIEEISLRSLFWAESENSNTFRSKSGKDASFESGAG---DNTSIKDK 2029
Query: 1155 IQVRGRLDCGMAF-AGDEVLVQLLSGDKA 1182
+ G +D G F AG+E + S KA
Sbjct: 2030 FEAAGGVDIGSWFCAGNENTSEDKSAPKA 2058
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 37.0 bits (84), Expect = 0.26
Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 14/149 (9%)
Query: 920 SFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGA-AGNWEAAP 978
S A G++ +S E SV EG + VE G G +AG AG+ A
Sbjct: 219 SVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGD-----GVEAGVPAGDSVEAE 273
Query: 979 EPVGDLAEEQAAVVTAM-VKAEP---GDEALSPASRDITATTAQTEAAAAP---AGDAVK 1031
P GD + + A V EP GD +LSP + I ++ A +P A DA +
Sbjct: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES-AGRSPGELAWDAAE 332
Query: 1032 EDVVPGACAAGAAAAAGVESTEAEDAEAD 1060
E VPG + AA + ED D
Sbjct: 333 EAEVPGVKGSEEAAPGDARADAGEDRVGD 361
>gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]
Length = 1082
Score = 36.2 bits (82), Expect = 0.44
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 15/78 (19%)
Query: 20 PPAPDGDGRTAPLGQPPGA---------------QLYCPACLVTCHSQEAFENHCASSEH 64
PP GR AP +P A LYCP C VT +S + H ++H
Sbjct: 846 PPCSPEPGREAPGPEPAAAAVGSSMSGEGRSEKGHLYCPTCKVTVNSASQLQAHNTGAKH 905
Query: 65 AQMVAFDQALPWEHRSPP 82
M+ + P R P
Sbjct: 906 RWMMEGQRGAPRRSRGRP 923
>gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]
Length = 1082
Score = 36.2 bits (82), Expect = 0.44
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 15/78 (19%)
Query: 20 PPAPDGDGRTAPLGQPPGA---------------QLYCPACLVTCHSQEAFENHCASSEH 64
PP GR AP +P A LYCP C VT +S + H ++H
Sbjct: 846 PPCSPEPGREAPGPEPAAAAVGSSMSGEGRSEKGHLYCPTCKVTVNSASQLQAHNTGAKH 905
Query: 65 AQMVAFDQALPWEHRSPP 82
M+ + P R P
Sbjct: 906 RWMMEGQRGAPRRSRGRP 923
>gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens]
Length = 1082
Score = 36.2 bits (82), Expect = 0.44
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 15/78 (19%)
Query: 20 PPAPDGDGRTAPLGQPPGA---------------QLYCPACLVTCHSQEAFENHCASSEH 64
PP GR AP +P A LYCP C VT +S + H ++H
Sbjct: 846 PPCSPEPGREAPGPEPAAAAVGSSMSGEGRSEKGHLYCPTCKVTVNSASQLQAHNTGAKH 905
Query: 65 AQMVAFDQALPWEHRSPP 82
M+ + P R P
Sbjct: 906 RWMMEGQRGAPRRSRGRP 923
>gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]
Length = 274
Score = 35.8 bits (81), Expect = 0.58
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 5/118 (4%)
Query: 943 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPV----GDLAEEQAAV-VTAMVK 997
P +E+ +G P G++ G P GD A EQAA A +
Sbjct: 109 PVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSE 168
Query: 998 AEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAE 1055
+ G A++ T + ++A APA + K+ VP A A AA E A+
Sbjct: 169 EKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAK 226
>gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]
Length = 238
Score = 35.8 bits (81), Expect = 0.58
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 5/118 (4%)
Query: 943 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPV----GDLAEEQAAV-VTAMVK 997
P +E+ +G P G++ G P GD A EQAA A +
Sbjct: 73 PVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSE 132
Query: 998 AEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAE 1055
+ G A++ T + ++A APA + K+ VP A A AA E A+
Sbjct: 133 EKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAK 190
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 35.0 bits (79), Expect = 0.98
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 944 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 1003
+GL+ ++EQ P R Q A + P P G + VT +++A PG
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198
Query: 1004 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 1038
+ SPAS + T A E PA VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 35.0 bits (79), Expect = 0.98
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 944 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 1003
+GL+ ++EQ P R Q A + P P G + VT +++A PG
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198
Query: 1004 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 1038
+ SPAS + T A E PA VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 35.0 bits (79), Expect = 0.98
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query: 944 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 1003
+GL+ ++EQ P R Q A + P P G + VT +++A PG
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198
Query: 1004 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 1038
+ SPAS + T A E PA VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 34.3 bits (77), Expect = 1.7
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 16/104 (15%)
Query: 1881 DTLQVQLGTSLQHGFLVPSPQLWTVAPGF----SLCLEHVERPGDCFSGRVYRAPRDRYR 1936
D +Q + LQ + S W G+ S+ +E V+R G+ S R YR P D+ +
Sbjct: 3611 DVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLK 3670
Query: 1937 DVDEYACVWEPFCALESATGAVAENDSVTL-QHL-SVSWEASRT 1978
C ++ +A+N+++T+ +HL + +W+A +T
Sbjct: 3671 FT----------CITDTPEIVLAKNNALTMSKHLYTEAWDADKT 3704
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,817,012
Number of Sequences: 37866
Number of extensions: 5707162
Number of successful extensions: 16119
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 15815
Number of HSP's gapped (non-prelim): 241
length of query: 2649
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2530
effective length of database: 13,741,464
effective search space: 34765903920
effective search space used: 34765903920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.