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Search of human proteins with 150417989
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150417989 cyclin K isoform 1 [Homo sapiens]
(580 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150417989 cyclin K isoform 1 [Homo sapiens] 1253 0.0
gi|38176158 cyclin K isoform 2 [Homo sapiens] 644 0.0
gi|160707881 formin 2 [Homo sapiens] 148 2e-35
gi|17978466 cyclin T1 [Homo sapiens] 147 3e-35
gi|17978469 cyclin T2 isoform b [Homo sapiens] 135 1e-31
gi|4502629 cyclin T2 isoform a [Homo sapiens] 135 1e-31
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 130 3e-30
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 121 2e-27
gi|9945320 cyclin L1 [Homo sapiens] 118 1e-26
gi|88758580 cyclin L2 isoform A [Homo sapiens] 115 8e-26
gi|47132519 Ras association and pleckstrin homology domains 1 is... 115 8e-26
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 1e-25
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 114 2e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 113 4e-25
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 112 7e-25
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 111 2e-24
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 111 2e-24
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 111 2e-24
gi|11386183 WAS protein family, member 2 [Homo sapiens] 108 2e-23
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 108 2e-23
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 107 4e-23
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 107 4e-23
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 106 7e-23
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 106 7e-23
gi|150170670 piccolo isoform 2 [Homo sapiens] 105 9e-23
gi|150378539 piccolo isoform 1 [Homo sapiens] 105 9e-23
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 105 1e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 104 3e-22
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 103 3e-22
gi|196049382 family with sequence similarity 58, member A isofor... 103 3e-22
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 1253 bits (3242), Expect = 0.0
Identities = 580/580 (100%), Positives = 580/580 (100%)
Query: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
Sbjct: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
Query: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
Sbjct: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
Query: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
Sbjct: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
Query: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
Sbjct: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
Query: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
Sbjct: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
Query: 301 QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET 360
QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET
Sbjct: 301 QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET 360
Query: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP
Sbjct: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
Query: 421 PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPP 480
PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPP
Sbjct: 421 PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPP 480
Query: 481 NPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGL 540
NPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGL
Sbjct: 481 NPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGL 540
Query: 541 PPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR 580
PPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR
Sbjct: 541 PPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR 580
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 644 bits (1662), Expect = 0.0
Identities = 314/342 (91%), Positives = 318/342 (92%), Gaps = 14/342 (4%)
Query: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
Sbjct: 1 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV 60
Query: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
Sbjct: 61 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA 120
Query: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
Sbjct: 121 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK 180
Query: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
Sbjct: 181 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ 240
Query: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
Sbjct: 241 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS 300
Query: 301 QPQQKDP---------QQPAQQQQPAQQP-----KKPSPQPS 328
QPQQKDP +QPA P+ +P P P+
Sbjct: 301 QPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPA 342
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 148 bits (373), Expect = 2e-35
Identities = 110/298 (36%), Positives = 126/298 (42%), Gaps = 31/298 (10%)
Query: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP 353
S SS P P P P PQP P Q + P A PPPP
Sbjct: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP-PLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 354 KIPKIETTH-PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQ 412
+P PPLP A PP PPL A PP P+ +P +PPP A +
Sbjct: 925 PLPGAGILPLPPLPGAGIPPP--PPLPGAA--IPPPPPLPGAGIP---LPPPLPGAGIPP 977
Query: 413 PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP 472
PPPLP PPPP G+ + G G + P G PP P A +P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPL-----PGAGIPPPPPLPGAGIP 1031
Query: 473 YHPHVYPPN-PPPPPVP----PPPASFPPPAIPPPTP----GYPPPPPTYNPNFPPPPPR 523
P + PPPPP+P PPP P IPPP P G PPPPP PPPPP
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP- 1090
Query: 524 LPPTHAVPPHPPPGLGLPP------ASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGR 575
LP PP P PG+G+PP A PPP PG P PPP+P G+PP L R
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148
Score = 147 bits (371), Expect = 3e-35
Identities = 114/317 (35%), Positives = 132/317 (41%), Gaps = 35/317 (11%)
Query: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS--- 329
+ QPP LQ T +P P P P P A P P P P +
Sbjct: 896 IPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPP-PLPGAAIP 954
Query: 330 -PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEP 387
P + A + P A PPPP +P PP LP A PP PPL A P
Sbjct: 955 PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGA--GIPP 1010
Query: 388 PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSL 447
P P+ +P PPP A + PPPLP PPPP G+ + G G
Sbjct: 1011 PPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPP 1066
Query: 448 QSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN-PPPPPVP----PPPASFPPPAIPPP 502
+ P G PP P A +P P + PPPPP+P PPP P IPPP
Sbjct: 1067 PPL-----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121
Query: 503 TP----GYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP------ASYPPPAVPP 552
P G PPPPP PPPPP LP PP P PG G+PP A PPP P
Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPPPP-LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Query: 553 GGQPPVPPPIPPPGMPP 569
G P PPP+P G+PP
Sbjct: 1181 GVGIPPPPPLPGVGIPP 1197
Score = 138 bits (347), Expect = 2e-32
Identities = 110/314 (35%), Positives = 131/314 (41%), Gaps = 35/314 (11%)
Query: 278 SLQPTPQVPQVQQSQPSQ---SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS----P 330
++ P P +P P + P P P P P P P + P
Sbjct: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEPPG 389
+ A + P A PPPP +P PP LP A PP PPL A PP
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGA--GIPPPP 1067
Query: 390 PVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQS 449
P+ +P PPP A + PPPLP PPPP G+ + G G
Sbjct: 1068 PLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP-LPGAGIPPPPP 1123
Query: 450 MMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN-PPPPPVP----PPPASFPPPAIPPPTP 504
+ P G PP P A +P P + PPPPP+P PPP P IPPP P
Sbjct: 1124 L-----PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Query: 505 ----GYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPP 560
G PPPPP PPPPP LP PP P PG+G+PPA PP PPG P PP
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPP-LPGAGIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPP 1236
Query: 561 PIP---PPGMPPVG 571
+P PP +P VG
Sbjct: 1237 LLPVSGPPLLPQVG 1250
Score = 129 bits (323), Expect = 1e-29
Identities = 105/306 (34%), Positives = 126/306 (41%), Gaps = 71/306 (23%)
Query: 287 QVQQSQPSQS-SEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Q+ QP+QS S+P P A Q QP QP S+ Q VS +N
Sbjct: 797 QLDSHQPTQSISQPPPPPSL--LWSAGQGQPGSQPPHSI---STEFQTSHEHSVSSAFKN 851
Query: 346 KAAEPPPPKIPKIETTH--------PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP 397
P PP +P E++ PP PP P P P + +PP P+ T++
Sbjct: 852 SCNIPSPPPLPCTESSSSMPGLGMVPPPPP--PLPGMTVPTLPSTAIPQPP-PLQGTEM- 907
Query: 398 KVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPS 457
+PPP PPPLP PPPP + G G L + P
Sbjct: 908 ---LPPP--------PPPLPGAGIPPPPP------------LPGAGILPLPPL-----PG 939
Query: 458 YGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP----AIPPPTP----GYPPP 509
G PP P A +P PPPP+P PPP IPPP P G PPP
Sbjct: 940 AGIPPPPPLPGAAIP----------PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP 989
Query: 510 PPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP------ASYPPPAVPPGGQPPVPPPIP 563
PP PPPPP LP PP P PG G+PP A PPP PG P PPP+P
Sbjct: 990 PPLPGAGIPPPPP-LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
Query: 564 PPGMPP 569
G+PP
Sbjct: 1049 GAGIPP 1054
Score = 100 bits (249), Expect = 4e-21
Identities = 97/323 (30%), Positives = 116/323 (35%), Gaps = 71/323 (21%)
Query: 279 LQPTPQVPQVQQSQPSQ---SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS----PR 331
+ P P +P P + P P P P P P P + P
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
Query: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEPPGP 390
+ A + P A PPPP +P PP LP A PP PP +G PP P
Sbjct: 1057 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPLPGVG-IPPPPP 1112
Query: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
+ +P PPP A + PPPLP PPPP G+
Sbjct: 1113 LPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL------------ 1157
Query: 451 MKTEGPSYGALPPAYGPPAHLPYHPHV----YPPNPP------PPPVPPPPASFPPPAIP 500
P G PP P A +P P + PP PP PPP P P A PPP
Sbjct: 1158 -----PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP--- 1209
Query: 501 PPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY----PPPAVPPGGQP 556
PP PG PP P PP PPPG G+PP PP +P G
Sbjct: 1210 PPLPGM---------GIPPAP--------APPLPPPGTGIPPPPLLPVSGPPLLPQVGSS 1252
Query: 557 PVPPP-----IPPPGMPPVGGLG 574
+P P +PPP + GLG
Sbjct: 1253 TLPTPQVCGFLPPPLPSGLFGLG 1275
Score = 99.8 bits (247), Expect = 6e-21
Identities = 90/295 (30%), Positives = 113/295 (38%), Gaps = 75/295 (25%)
Query: 335 RAVVVSPKEENKAAE-PPPPKIPKIETTHPPLPP-AHPPPDRKPPLAAALGEAEPPGPVD 392
+++ SP EE PP +P PP PP A P K + + P +
Sbjct: 742 KSIQTSPTEEGGVLTLPPVDGLPG----RPPCPPGAESGPQTK--FCSEISLIVSPRRIS 795
Query: 393 ATDLPKVQIPPPAHPAPVHQPPPLPH--------RPPPPPPSSYMTGMSTTSSYMSGEGY 444
VQ+ + QPPP P +P PP S T T+ + +
Sbjct: 796 ------VQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAF 849
Query: 445 QSLQSMMK------TEG----PSYGALPPAYGPPAHLPYH-----PHVYPPNPPP----P 485
++ ++ TE P G +PP PP LP P P PPP
Sbjct: 850 KNSCNIPSPPPLPCTESSSSMPGLGMVPP---PPPPLPGMTVPTLPSTAIPQPPPLQGTE 906
Query: 486 PVPPPPASFPPPAIPPPTP---------------GYPPPPPTYNPNFPPPPP------RL 524
+PPPP P IPPP P G PPPPP PPPPP L
Sbjct: 907 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL 966
Query: 525 PPT---HAVPPHPP-PGLGLPP------ASYPPPAVPPGGQPPVPPPIPPPGMPP 569
PP +PP PP PG G+PP A PPP PG P PPP+P G+PP
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021
Score = 73.2 bits (178), Expect = 6e-13
Identities = 56/173 (32%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 411 HQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAH 470
HQP +PPPPP + G S + S+ + +T ++ A+ +
Sbjct: 801 HQPTQSISQPPPPPSLLWSAGQGQPGS----QPPHSISTEFQTSHEH--SVSSAFKNSCN 854
Query: 471 LPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFP----PPPPRLPP 526
+P +PPP P +S P + PP P PP P P P P PP L
Sbjct: 855 IP--------SPPPLPCTESSSSMPGLGMVPPPP--PPLPGMTVPTLPSTAIPQPPPLQG 904
Query: 527 THAVPPHPPP--GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAA 577
T +PP PPP G G+PP PP +P G P+PP +P G+PP L AA
Sbjct: 905 TEMLPPPPPPLPGAGIPP----PPPLPGAGILPLPP-LPGAGIPPPPPLPGAA 952
Score = 36.6 bits (83), Expect = 0.065
Identities = 41/151 (27%), Positives = 58/151 (38%), Gaps = 14/151 (9%)
Query: 274 QQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQV 333
+Q L Q ++QQ Q Q Q QQ+ QQ ++PA P SPQP + +
Sbjct: 191 EQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQ-QQLQGAEEPAAPPTAVSPQPGAFLGL 249
Query: 334 KRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP---PAHPPPDRKPPLAAALGEAEPPGP 390
R ++ +A P P + + LP A P ++PP L +E P
Sbjct: 250 DRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP-- 305
Query: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPP 421
LP Q P A +P P P P
Sbjct: 306 ----SLPAAQ--PAAKDSPSSTAFPFPEAGP 330
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 147 bits (371), Expect = 3e-35
Identities = 86/259 (33%), Positives = 141/259 (54%), Gaps = 23/259 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
WY+ ++ L ++PS+ G+DP E YR++ A + D+G RL + T+ T I+Y HRFYM
Sbjct: 12 WYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYM 71
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKE----- 138
SF QFP LFLA KVEE PKK + +IK A + L+ + D E
Sbjct: 72 IQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQE--SLPDTRSEAYLQQ 129
Query: 139 --EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTT 196
++++LE I+LQT+ F+L ++HP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 VQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMA---TNSLHLTT 186
Query: 197 LSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILD 256
SLQ+ P ++A ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 FSLQYTPPVVACVCIHLACKWSNWEIPVSTDG---KHWWEYVDATVTLELLDELTHEFL- 242
Query: 257 LYSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 243 -------QILEKTPNRLKR 254
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 135 bits (339), Expect = 1e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
Query: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
Query: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
Query: 258 YSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 242 ------QILEKTPNRLKK 253
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 135 bits (339), Expect = 1e-31
Identities = 80/258 (31%), Positives = 142/258 (55%), Gaps = 21/258 (8%)
Query: 24 WYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYM 83
W++ ++ L +TPS+ G++ E R++ A I ++G RL + T+ T I+Y HRFYM
Sbjct: 11 WFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYM 70
Query: 84 FHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLN------DVQFGQFGDDPK 137
HSF +F + + + LFLA KVEE +K + +IK A + L+ D + +
Sbjct: 71 HHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQ-T 129
Query: 138 EEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTL 197
+E+++LE I+LQT+ F++ +EHP+ ++K + ++ K+ Q MA N TT
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMA---TNSLHLTTF 186
Query: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
LQ++P +IA ++LA + +EI T + WWE V +++L+++ H+ L
Sbjct: 187 CLQYKPTVIACVCIHLACKWSNWEIPVSTDG---KHWWEYVDPTVTLELLDELTHEFL-- 241
Query: 258 YSQGKQQMPHHTPHQLQQ 275
Q+ TP++L++
Sbjct: 242 ------QILEKTPNRLKK 253
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 130 bits (328), Expect = 3e-30
Identities = 102/323 (31%), Positives = 128/323 (39%), Gaps = 58/323 (17%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQP----SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325
P LQ PP+ TP + + P + S+ + P + P PA P Q P PSP
Sbjct: 520 PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC--PLQAP--PSP 575
Query: 326 QPSSPRQVKRAVVVSPKEENKA-AEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGE 384
+ P + ++ P + A A PP +P PPL P PP + PP A
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPS-----PPLSPLATPPPQAPPXLALPPL 630
Query: 385 AEPPGPVDATDLPKVQIPPPAHP---------APVHQPPPLPHRPPPPPPSSYMTGMSTT 435
PP P + L + P P P AP PP P + P PP+S S T
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 436 SSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP---PPPVPPPPA 492
P A P PP +P P PP P PPP PPP
Sbjct: 691 --------------------PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Query: 493 SFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA-----VPPHPPPGLGLPPASYPP 547
+ PP +PP P PP P+ P PPR+PP A VPP PP L + P + PP
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATP-----PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 548 PAVPPG-GQPPVPP-PIPPPGMP 568
P PP PP+ P PP P
Sbjct: 786 PQAPPALATPPLQALPSPPASFP 808
Score = 121 bits (303), Expect = 2e-27
Identities = 116/397 (29%), Positives = 136/397 (34%), Gaps = 92/397 (23%)
Query: 263 QQMPHHTPHQLQQPPSLQPTP--QVPQVQQSQPSQSSEPSQPQQKDPQ------------ 308
Q P T +Q PPSLQ P QVP + PS + PS Q
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
Query: 309 -------QPAQQQQPAQQPKKPSPQP--------------SSPRQVKRAVVVSPKEENKA 347
P Q Q P +P+ P S P Q + VSP
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
Query: 348 AEP---------PPPKIPKIETTHPPL-------PPAHPPPDRK---PPLAAALGEAEPP 388
P P+ P PPL PP+ P PPL A PP
Sbjct: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545
Query: 389 GPVDATDL--PKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQS 446
+ L P ++ PP P P+ PP PPP PSS T ++ Q
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 447 LQS-------MMKTEGPSYGALPPAY---GPPAHLPYHPHVYP-PNPP------------ 483
L S + P ALPP PPA P P P P P
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665
Query: 484 -PPPVPPPPASFPPPAIPPPTPGYPPP---------PPTYNPNFPPPPPRLPPTHAVPPH 533
PPP PP A F PPA PP +P PP PP P PP P + P+ PP
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 534 PPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
PP L PP PP PP P P PPP +PP+
Sbjct: 726 APPPLAAPPLQVPPS--PPASPPMSPSATPPPRVPPL 760
Score = 113 bits (282), Expect = 5e-25
Identities = 98/308 (31%), Positives = 119/308 (38%), Gaps = 23/308 (7%)
Query: 269 TPHQLQQPPSLQP-TPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQP 327
T H LQ SL +PQ P P ++ S PA P + PS P
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE-NLPSLAP 543
Query: 328 SSPRQVKRAVVVSPKEENKAAEPPPP--KIPKIETTHPPLPP---AHPPPDRKPPLAAAL 382
P Q A + +P E P P P TT PP P A PPP P LA+
Sbjct: 544 P-PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 383 GEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE 442
+ P P+ P Q PP P+ PP P PP P ++T S
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP-------LATPSPQAPNA 655
Query: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP 502
L + PS P + PPA P V P PP PP A+ PP +PP
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAP-FSPPAS----PPVSPSATPPSQAPPSLAA-PPLQVPPS 709
Query: 503 TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPP--GGQPPVPP 560
P PP P+ P PPP P VPP PP + P++ PPP VPP P P
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769
Query: 561 PIPPPGMP 568
P PP +P
Sbjct: 770 PSPPASLP 777
Score = 108 bits (270), Expect = 1e-23
Identities = 93/312 (29%), Positives = 118/312 (37%), Gaps = 44/312 (14%)
Query: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQS--SEPSQPQQKDPQQ--PAQQQQPAQQPK 321
P TP + PP PQ P S P Q S P P P Q P P Q P
Sbjct: 580 PPETPSSIATPP-----PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
Query: 322 KP------SPQPSSPRQVKRAVVVSPKEENKAAEPPPP-KIPKIETTHPPLPPAHPPPDR 374
P SP + Q A+ V + + P PP + P PP+ P+ PP +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMST 434
PP AA PP P + + PPP P P+ PP PP PP S M+ +T
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL--QVPPSPPASPPMSPSAT 752
Query: 435 TSSYMSGEGYQSLQSMMKTEGPSYGALPPAY---GPPAHLPYHPHVYPPNPPPPPVPPPP 491
+ P A PP PPA LP P PP PP + PP
Sbjct: 753 PPPRV----------------PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
Query: 492 ASFPPPAIPPPTPGYPPPPPTYNPN--FPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPA 549
A+P P +P P ++P+ P P PP A P P L +PP+ P
Sbjct: 797 LQ----ALPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 550 VPPGGQPPVPPP 561
+ +PP P P
Sbjct: 852 LQAPRRPPTPGP 863
Score = 98.2 bits (243), Expect = 2e-20
Identities = 99/331 (29%), Positives = 124/331 (37%), Gaps = 53/331 (16%)
Query: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKR 335
PP P P P + PS + PS P Q P P Q PS Q P QV
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP-PSLQTIPPIQVPH 393
Query: 336 AVVVSPKEENKAAEPPPPKI------------PKIETTHP---------------PLPPA 368
++ SP + PP P P ++ TH P PA
Sbjct: 394 SLT-SPSLQ----APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP----HRPPPPP 424
PPD PPL A L P P+ + P V P + P +H L H P P
Sbjct: 449 STPPD-SPPLQAPLSLPASP-PLQTSLSPAVS--PLSSPLTIHPLQALSSLASHSPQAPL 504
Query: 425 PSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP 484
S M + T SS ++ Q+ + + T P LP PP P
Sbjct: 505 SSLIMPPLETQSS-LAPPSLQTPPASLTT--PPLENLPSLAPPPLQTASAPLT------T 555
Query: 485 PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP-HPPPGLGLPPA 543
P + PP P P PP+P PPP T + + PPP+ PP A PP P L P
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPS-SIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 544 SYPPPAVPPG-GQPPVPPPIPPPGMPPVGGL 573
+ PPP PP PP+ P PP PP+ L
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Score = 79.3 bits (194), Expect = 9e-15
Identities = 90/302 (29%), Positives = 107/302 (35%), Gaps = 51/302 (16%)
Query: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQ-----PAQQP 320
P TP PP P QVP + P S + P + P A Q PA P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 321 KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHP----PLPPAHPPPDRKP 376
P +P P Q A+ P + A PP P P P+ P PP + P
Sbjct: 778 MSPLAKP--PPQAPPALATPPLQ---ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 377 PLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPP----PLPHRPPPPP---PSSYM 429
P+ AA PP P + L + PP P P L PPPPP PSS +
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Query: 430 TG-------MSTTSSYMSGEGYQSLQSMMKTEGPSYGAL--PPAYGPPAHL-PYHPHVYP 479
+G S TS+ GY S GP GA PP P A L HP +
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDS--------GPEGGAAASPP---PDAELAACHPAAWS 941
Query: 480 PNPPPP----PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP 535
P PP P P +PP P G T P P P A+ P P
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP-----GALDPGPS 996
Query: 536 PG 537
PG
Sbjct: 997 PG 998
Score = 75.5 bits (184), Expect = 1e-13
Identities = 81/319 (25%), Positives = 108/319 (33%), Gaps = 51/319 (15%)
Query: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPS 324
+P P +PP+ P V + ++EPS ++ P Q+PA + S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 325 PQP-SSP-------RQVKRAVV--VSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDR 374
P SSP R RA PK + A PP P + P L P P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMST 434
P + PP AT LP P P P+ PP P PP
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP------------- 352
Query: 435 TSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASF 494
SLQ++ PS A PP+ PP+ PP PP + P
Sbjct: 353 -----------SLQTL-----PSPPATPPSQAPPS------MTTPPMQAPPSLQTIPPIQ 390
Query: 495 PPPAIPPPTPGYPPPP---PTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP 551
P ++ P+ PP P + P L TH+ P S PA
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450
Query: 552 PGGQPPVPPPIPPPGMPPV 570
P PP+ P+ P PP+
Sbjct: 451 PPDSPPLQAPLSLPASPPL 469
Score = 62.4 bits (150), Expect = 1e-09
Identities = 76/293 (25%), Positives = 102/293 (34%), Gaps = 44/293 (15%)
Query: 302 PQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE-- 359
P++ A++ P PSP + + V P+ A PP + P+
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 360 -----TTHPPLPPAHPPPDR----KPPLAAALGEAEPPGPVDATDLPKVQIPP--PAHPA 408
+T P P A P + P + +L + P A P + P PAHP+
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 409 PVHQPPPL---PHRPPP--PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
QP P RPP PP + SS S + T PS
Sbjct: 271 ---QPKPKGLQALRPPQVTPPRKDAAPALGPLSS-----------SPLATPSPS------ 310
Query: 464 AYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR 523
G A P P P P +PP P P + PP+P PP T PP +
Sbjct: 311 --GTKAR-PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
Query: 524 LPPTHAVPP-HPPPGL-GLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
PP+ PP PP L +PP P P Q P P P+ + LG
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATTSLG 419
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/292 (23%), Positives = 88/292 (30%), Gaps = 71/292 (24%)
Query: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPL-----AAALGE---AEPPGPVDATDLPK 398
AA P + P + T PP P PPP L A A+G AE G + +P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP- 71
Query: 399 VQIPPPAHPA---------PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE------G 443
+ P A P P +PP PP + G ++ SG G
Sbjct: 72 -ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 444 YQSLQSMMK--------TEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFP 495
+ L+ + TE P AL P P P P A+
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP-----TPGTPSPAMARRSRAAGT 185
Query: 496 PPAIPPPTPGYPPPPPTYNP------------NFPPPPPRLPP--------------THA 529
+P P P P PPT P P P R P + +
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 530 VPPHPPPGLGLPPA-------SYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
P P P A ++P P G Q PP + PP LG
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 121 bits (303), Expect = 2e-27
Identities = 106/348 (30%), Positives = 128/348 (36%), Gaps = 87/348 (25%)
Query: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
G++Q HH H Q + P PQ P P PQQ P P QQQQ QP
Sbjct: 732 GREQKKHHHHHHQQMQQAPAPVPQQP------------PPPPQQPPPPPPPQQQQ---QP 776
Query: 321 KKPSPQPSSPRQVKRAV-------------VVSPKEENKAAEP-----------PPPKIP 356
P P PS P+Q A+ V+ P+ +P P P++P
Sbjct: 777 PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP 836
Query: 357 KIETTHPPLPPAHPPPDR-------KPPLAAALGEAEPPGPVD-ATDLPKVQIPPPAHPA 408
H P PP H P PP +P P + A LP PPA
Sbjct: 837 P----HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSP 892
Query: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQS-LQSMMKTEGPSYGALPPAYGP 467
+ Q P LP P PP + + ++ Q LQ + K + P+
Sbjct: 893 ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT---------- 942
Query: 468 PAHLPYHPHVYPPNPPPPPVPPPP-------ASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
P P V + PPPP+PPPP PP PPP P P PPP PP
Sbjct: 943 ----PLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP--PPPPPQ-PQPPPQQQHQPPPR 995
Query: 521 PPRLPP----THAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564
P L P TH P PP G PP PPG QPP P P P
Sbjct: 996 PVHLQPMQFSTHIQQPPPPQG-------QQPPHPPPGQQPPPPQPAKP 1036
Score = 82.0 bits (201), Expect = 1e-15
Identities = 108/443 (24%), Positives = 136/443 (30%), Gaps = 141/443 (31%)
Query: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQ---- 313
+ Q QQ P P Q PP P P PQ QQ P PS PQQ P +
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 314 --QQPAQQPKKPS-------------------------PQP---SSPRQVKRAVVVSP-- 341
Q P +P+ P PQP S+P + + VVSP
Sbjct: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861
Query: 342 ----------KEENKAAEPPP-----PKIPKIETTHP--PLPPAHPPP-----DRKPPLA 379
+ N+AA PP P + T P P PP PP D +PP
Sbjct: 862 LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
Query: 380 AA-----------LGEAEPPGPVDATDLPKVQI---PPPAHPAPVH---------QPPPL 416
L + +PP P+ LP V++ PPP P P H QPPP
Sbjct: 922 PLTSMQMQLYLQQLQKVQPPTPL----LPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP 977
Query: 417 PHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHP- 475
P P PPP + +Q +G PP PP P P
Sbjct: 978 PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037
Query: 476 -----HVYPPNPPPPPVP-------PPPASFPPPAIP---------PPTPGYPP------ 508
H P + P P P P + PP P
Sbjct: 1038 QVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELR 1097
Query: 509 ------PPPT-----------------YNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545
P P ++P+ P PP+ P + P H P + P
Sbjct: 1098 AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDV 1157
Query: 546 PPPAVPPGGQPPVPPPIPPPGMP 568
P + P Q PPPG P
Sbjct: 1158 GRPVIRPPEQ-----NAPPPGAP 1175
Score = 76.3 bits (186), Expect = 7e-14
Identities = 83/305 (27%), Positives = 111/305 (36%), Gaps = 66/305 (21%)
Query: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP 353
S SE S + ++ + + KK P R+ K+ ++ +A P P
Sbjct: 700 SSESESSSESSSSDSEDSETEMAPKSKKKGHPG----REQKKHHHHHHQQMQQAPAPVPQ 755
Query: 354 KIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQP 413
+ PP PP PPP P + +PP P P +P A PA P
Sbjct: 756 Q--------PPPPPQQPPPPPPPQQ-----QQQPPPPP-----PPPSMPQQAAPAMKSSP 797
Query: 414 PP-----LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468
PP +P P P S + G Q + + + E P + PP + P
Sbjct: 798 PPFIATQVPVLEPQLPGSVFDP---------IGHFTQPILHLPQPELPPHLPQPPEHSTP 848
Query: 469 AHLPYHPHVYPP--NPPPPPVPPPPASFPPPAIPPPTPGYPP---PPPTYNPNFPPPPPR 523
HL H V PP + P P P++ A PP P PP P T P P PP
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSN--RAAALPPKPARPPAVSPALTQTPLLPQPPMA 906
Query: 524 LPPTHAVPPHPPPGLGLPPAS--------------YPP----PAVPPGGQPPVPPPIPPP 565
PP + PP PP + PP P+V QPP PP+PPP
Sbjct: 907 QPPQVLLEDEEPPA---PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP--PPLPPP 961
Query: 566 GMPPV 570
P V
Sbjct: 962 PHPSV 966
Score = 65.1 bits (157), Expect = 2e-10
Identities = 91/394 (23%), Positives = 118/394 (29%), Gaps = 137/394 (34%)
Query: 300 SQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE 359
SQPQQ P++ + ++ ++ K KR V +++KA EPPP K K
Sbjct: 529 SQPQQNKPKKKEKDKKEKKKEKH-----------KRKEEVEENKKSKAKEPPPKKTKKNN 577
Query: 360 TTHPPLPPAHPPPDR-KPPLAAALGEAEPPGPV----------DATDLPKVQIPPPAHPA 408
+++ + P P + KPP E + P+ D LP ++ H
Sbjct: 578 SSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHII 637
Query: 409 PVHQPPPLPHRP-------------------------------PPPPPSSYMTGMSTTSS 437
+P P P + G S
Sbjct: 638 QSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKG 697
Query: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAH-----LPYHPHVY----------PPNP 482
+ S E S +S S + P H +H H + P P
Sbjct: 698 FSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP 757
Query: 483 PPPPV--PPPP----ASFPPPAIPPPTPGYP----------PPP------PTYNPNFP-- 518
PPPP PPPP PPP PPP P P PPP P P P
Sbjct: 758 PPPPQQPPPPPPPQQQQQPPP--PPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS 815
Query: 519 --------------------PPPPRLPPTHAVPPH-------PPPGL------------- 538
PP PP H+ PPH PP L
Sbjct: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN 875
Query: 539 ---GLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
LPP PPAV P P PP PP
Sbjct: 876 RAAALPPKPARPPAVSPALTQTPLLPQPPMAQPP 909
Score = 47.0 bits (110), Expect = 5e-05
Identities = 34/106 (32%), Positives = 39/106 (36%), Gaps = 12/106 (11%)
Query: 462 PPAYGPPAHLP-YHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
PP P P P + P VPP P PPP P P PPP P P P
Sbjct: 216 PPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP---QPPPAPA-----PQP 267
Query: 521 PPRLPPTHAVPPHP---PPGLGLPPASYPPPAVPPGGQPPVPPPIP 563
PP A P P G+ + P + P +PP PP P
Sbjct: 268 VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 14/119 (11%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEP---SQPQQKDPQQPAQQQQPAQQPKKPSP- 325
P LQ PP + P PQ P QP QS P + PQ ++ +++ P P
Sbjct: 244 PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
Query: 326 --QPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAAL 382
PS P + K + +E ++ +PP +P + HP P++ ++ L
Sbjct: 304 HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ--------QHPAPEKSSKVSEQL 354
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/162 (25%), Positives = 55/162 (33%), Gaps = 42/162 (25%)
Query: 261 GKQQMPHHTPHQLQQPPSLQ-PTPQVPQVQQS-QPSQSSEPSQPQQKDPQQPAQQQQPAQ 318
G +P+ T Q PP Q P P P VQ + P + P Q P QP Q
Sbjct: 192 GVSTVPNTT--QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQ 248
Query: 319 QPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPL 378
P PQP +PPP P+ +HPP+ A P P +
Sbjct: 249 TPPPVPPQP---------------------QPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
Query: 379 AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
+ P +D P+H+PP LP P
Sbjct: 288 VKRKADTTTPTTID----------------PIHEPPSLPPEP 313
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/107 (27%), Positives = 35/107 (32%), Gaps = 27/107 (25%)
Query: 490 PPASFPPPAIPPPTPGYPPPPPTYNPNF----------PPPPPRLPPTHAVPPHPPPGLG 539
PP + P PPP P P P P+ PP P + PP P PPP
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Query: 540 LPPASYPPPAVPPGGQP-----------------PVPPPIPPPGMPP 569
P PP + QP + P PP +PP
Sbjct: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP 311
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 342 KEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDA-TDLPKVQ 400
++E A+P +P TT PP P PP A P D P +
Sbjct: 183 RKETGTAKPGVSTVPN--TTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
Query: 401 IPPPAHPAPVHQPPPLPHRPPPPP 424
+ PP P+ PPP+P +P PPP
Sbjct: 241 VVPPQ---PLQTPPPVPPQPQPPP 261
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/93 (34%), Positives = 35/93 (37%), Gaps = 13/93 (13%)
Query: 482 PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRL----PPTHAVPPHPPPG 537
P VP + PP P P PP T +P FP P L P VPP P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-FPAVTPDLIVQTPVMTVVPPQP--- 246
Query: 538 LGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
L PP P P P P P P P PP+
Sbjct: 247 LQTPPPVPPQPQPP-----PAPAPQPVQSHPPI 274
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/150 (26%), Positives = 58/150 (38%), Gaps = 32/150 (21%)
Query: 349 EPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
+ P P P ++ T P P P + P+ + PP P+ Q PPP P
Sbjct: 209 QTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV----PPQPL--------QTPPPVPPQ 256
Query: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468
P QPPP P P P S+ ++ T + + + ++ T P+ + P + PP
Sbjct: 257 P--QPPP---APAPQPVQSHPPIIAATPQPVKTK--KGVKRKADTTTPT--TIDPIHEPP 307
Query: 469 AHLPYHPHV----------YPPNPPPPPVP 488
+ LP P P PP VP
Sbjct: 308 S-LPPEPKTTKLGQRRESSRPVKPPKKDVP 336
Score = 30.0 bits (66), Expect = 6.1
Identities = 18/88 (20%), Positives = 36/88 (40%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPK 321
K+++ + +L+ + + + + Q + Q QQ+ QQ A A P+
Sbjct: 1252 KERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQ 1311
Query: 322 KPSPQPSSPRQVKRAVVVSPKEENKAAE 349
S QP S +R + ++E + E
Sbjct: 1312 AQSSQPQSMLDQQRELARKREQERRRRE 1339
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 118 bits (296), Expect = 1e-26
Identities = 98/364 (26%), Positives = 170/364 (46%), Gaps = 54/364 (14%)
Query: 11 SVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDT 70
S S +DH+ ++ L+ TPS +GLD +E R G I G L L
Sbjct: 48 SEVSLTIDHS----LIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVA 103
Query: 71 LATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL------ 124
+ATG + FHRF+ SF + + C+ LA K+EE P++ +D+I L
Sbjct: 104 MATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKR 163
Query: 125 --NDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLV 182
+ + Q + K +V+ ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LV
Sbjct: 164 TPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QTLV 221
Query: 183 QMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDV 242
Q AW ++NDSL T + ++++PE IA A +YLA R + + P W+ F
Sbjct: 222 QTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPL------PTRPHWFLLF--GT 273
Query: 243 PVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQP------------TPQVPQVQQ 290
+ +++IC + L LY++ K ++ +LQ TP + +
Sbjct: 274 TEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGG 333
Query: 291 SQPSQSSEPSQP-----QQKDP---------QQPAQQQQPAQQP----KKPSPQPSSPRQ 332
P +S+PS P ++K P ++P +QQ ++ P +K S + + R
Sbjct: 334 FSP--ASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRS 391
Query: 333 VKRA 336
R+
Sbjct: 392 ASRS 395
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 115 bits (289), Expect = 8e-26
Identities = 96/357 (26%), Positives = 164/357 (45%), Gaps = 43/357 (12%)
Query: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
Query: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
Query: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWE 202
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W ++NDSL T + ++++
Sbjct: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSWNYMNDSLRTDVFVRFQ 236
Query: 203 PEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK 262
PE IA A +YLA R + + P W+ F + +++IC +IL LY++ K
Sbjct: 237 PESIACACIYLAARTLEIPL------PNRPHWFLLF--GATEEEIQEICLKILQLYARKK 288
Query: 263 QQMPH------HTPHQLQ----QPPSLQP------------TPQVPQVQQSQPSQSSEPS 300
+ H H ++ Q L P +P V+ + + S+PS
Sbjct: 289 VDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPS 348
Query: 301 QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPK 357
K+ + ++ + A++ K SP P+ + +E++ + P PK
Sbjct: 349 PLSVKNTK---RRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPK 402
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 115 bits (289), Expect = 8e-26
Identities = 103/351 (29%), Positives = 136/351 (38%), Gaps = 69/351 (19%)
Query: 278 SLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ----- 332
SL P P PQ + P +S+PS P P P P P P P S+P
Sbjct: 604 SLVP-PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662
Query: 333 --VKRAVVV----SPKEENKAAEPPPPKIPKIETTHPPL--PP----AHPPPDRKPPLAA 380
VK + + + + +PP P + + ++ P + PP PPP PP
Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722
Query: 381 ALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQ-----------PPPLPHRPPPPPPSSYM 429
+ P P A LP+ PPP P +HQ PPP P P P PP +
Sbjct: 723 SAMAQLKPAPC-APSLPQFSAPPP--PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 430 TGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPP 489
+ T + S + + + P+ +PPA PA + PP+PP PPVP
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPT-PPVPPAKKQPA---FPASYIPPSPPTPPVPV 835
Query: 490 PPASFPPP----AIPPPTPGYPPPPPTYN--PNFPPPP------------------PRLP 525
PP + P A PPP+P P P FPPPP P+ P
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895
Query: 526 P-THAVPPHPPPGLGLPPASYPPP------AVPPGGQPPVPPPIPPPGMPP 569
P A P P + +P +PPP PP PP P P PPP PP
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP--PPPSPVPAPPPPPPP 944
Score = 114 bits (286), Expect = 2e-25
Identities = 99/346 (28%), Positives = 122/346 (35%), Gaps = 68/346 (19%)
Query: 276 PPSLQPTPQVPQVQQSQPS------------------QSSEPSQPQQKDPQQPAQQQQ-- 315
PP P P P QS PS +S+ S K P P Q Q
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697
Query: 316 ------------PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHP 363
P P P P P S + +P +A PPP KI +++
Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757
Query: 364 PLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK---------VQIPPPAHPAPV---- 410
PP PPP PP+ A L PP P+ P Q PP PV
Sbjct: 758 VAPPTPPPP---PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 411 HQP-------PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
QP PP P PP P P + + + + S++K + PP
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQF---PP 871
Query: 464 AYGPPAHLPYHPHVYPPN--PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPP 521
PPA P N P PP + P +IP P+P +PPPPP + FPPPP
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931
Query: 522 PRLPPTHAVPPHPPPGLGLPPASYPPP------AVPPGGQPPVPPP 561
P P A PP PPP P P PGG+ P P P
Sbjct: 932 P--SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 97.4 bits (241), Expect = 3e-20
Identities = 96/312 (30%), Positives = 115/312 (36%), Gaps = 92/312 (29%)
Query: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPP 353
+Q E S+ + + +P P SPQP +V+P ++ + P PP
Sbjct: 585 TQLEESSKARMESMNRPYTSLVPPL-----SPQPK---------IVTPYTASQPSPPLPP 630
Query: 354 KIPKIETTHPPLPPAHPPPDRKPPL----AAALGEAEP---------------------- 387
P PP PP PPP PPL A + G A P
Sbjct: 631 PPP------PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684
Query: 388 ---PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
PV + K QI P P V PPP P PPPP P S M +
Sbjct: 685 KPPTPPVMQSQSVKPQILVP--PNGVVPPPPPP--PPPPTPGSAMAQLKPA--------- 731
Query: 445 QSLQSMMKTEGPSYGALPPAYGPPAHLPYHP--HVYPPNPPPPPVPPP-PASFPPPAIPP 501
P +LP PP L H H+ PP PP PPP PA PP A P
Sbjct: 732 -----------PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA--P 778
Query: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP----PGLGLPPASYPPPAVPPGGQPP 557
P P P PT P + P PP PP P PASY PP+ PP
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF---PASYIPPS------PP 829
Query: 558 VPP-PIPPPGMP 568
PP P+PPP +P
Sbjct: 830 TPPVPVPPPTLP 841
Score = 82.8 bits (203), Expect = 8e-16
Identities = 93/379 (24%), Positives = 125/379 (32%), Gaps = 88/379 (23%)
Query: 252 HQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQV------------PQVQQSQPSQSSEP 299
HQ+ + P P PP P P V P V Q+ P + P
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809
Query: 300 SQPQQKDPQQPAQQQQPAQQ-PKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI 358
P +K P PA P+ P P P P+ P+Q ++ A+PPP + +
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQ-----------QSFCAKPPPSPLSPV 858
Query: 359 ETT---------HPPLPPA------HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPP 403
+ PP PPA P P P + +A+P + +P PP
Sbjct: 859 PSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP 918
Query: 404 PAHPA----PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459
P + P P P+P PPPPPP++ S T G + KT P
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPPPPTA-----SPTPDKSGSPG----KKTSKTSSPGGK 969
Query: 460 ALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA---------IPPPTPGYPPPP 510
PP + + P P P V + F PPA +PPP PP P
Sbjct: 970 KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA--PPKP 1027
Query: 511 PTYNPNFPPPPPRL-------------------------PPTHAVPPHPPPGLGLPPASY 545
N + P L PP+ + P PPP LP
Sbjct: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087
Query: 546 PPPAVPPGGQPPVPPPIPP 564
PAV G P + P
Sbjct: 1088 EIPAVFSGNTSPKVAVVNP 1106
Score = 63.5 bits (153), Expect = 5e-10
Identities = 48/135 (35%), Positives = 52/135 (38%), Gaps = 39/135 (28%)
Query: 472 PYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAV- 530
PY V P +P P V P AS P P +PPP P PPPPP PPPPP LP A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPP----PPPPPPLPSQSAPS 656
Query: 531 -----------------------------PPHPPPGLGLPPASYPPPAVPPGGQPPVPPP 561
PP PP + + P VPP G V PP
Sbjct: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPP--VMQSQSVKPQILVPPNG---VVPP 711
Query: 562 IPPPGMPPVGGLGRA 576
PPP PP G A
Sbjct: 712 PPPPPPPPTPGSAMA 726
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 115 bits (288), Expect = 1e-25
Identities = 106/362 (29%), Positives = 135/362 (37%), Gaps = 69/362 (19%)
Query: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPS 324
+P P +PP+ P V + ++EPS ++ P Q+PA + S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 325 PQP-SSP-------RQVKRAVV--VSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDR 374
P SSP R RA PK + A PP P + P L P P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 375 KPPLAAALGEAEPPG----PVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP--PPSSY 428
P +AAL PP P ++ ++ P P P PP L P PP PPS
Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 365
Query: 429 MTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP----- 483
T + + + Q+ S + + S A PP PPA L P PP+PP
Sbjct: 366 TTSLGSPT-------LQATHSFLPSPPLSPLATPPPQAPPA-LALPPLQAPPSPPASPPL 417
Query: 484 ------------------------PPPVPPPPASFPPPAIPPPTPGYPPP---------P 510
PPP PP A F PPA PP +P PP P
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477
Query: 511 PTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP--ASYPPPAVPPG-GQPPVPP-PIPPPG 566
P P PP P + P+ PP PP L PP + PPP PP PP+ P PP
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537
Query: 567 MP 568
P
Sbjct: 538 FP 539
Score = 108 bits (270), Expect = 1e-23
Identities = 101/344 (29%), Positives = 126/344 (36%), Gaps = 55/344 (15%)
Query: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKK------PSPQPSSP 330
PS + TP+ P + + +P Q P P + PA P PSP +
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP--PRKDAAPALGPLSSSPLATPSPSAALQ 314
Query: 331 RQVKRAVVVSPKEENKAAE--PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP 388
Q + +P + + P P P + P L P P PP A P
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL-PSPPATPPSQATTSLGSPT 373
Query: 389 GPVDATDLPKVQIPPPAHPAPVHQP----PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
+ LP + P A P P P PPL PP PP S ++ ++T S
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASPPLSPLATPSPQAPNALA 432
Query: 445 QSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP--PAIPPP 502
L + PS P + PPA P P PP+ PP + PP PP PA PP
Sbjct: 433 VHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 503 TPGYPPPPPTYNPNFPPP------PPRLPPTHAVPPHPPPGLGLPPASYP---------- 546
+P PPP P PP PP+ PP A PP L PPAS+P
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSAS 549
Query: 547 ----PPAVPPGGQPPV-------PPPIPP-------PGMPPVGG 572
P A PP PPV PP PP P PP G
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Score = 105 bits (261), Expect = 1e-22
Identities = 89/298 (29%), Positives = 110/298 (36%), Gaps = 41/298 (13%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQS--------------SEPSQPQQKDPQQ--PAQQ 313
P PPSLQ P P SQ + S S P P P Q PA
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 314 QQPAQQPKKP------SPQPSSPRQVKRAVVVSPKEENKAAEPPPP-KIPKIETTHPPLP 366
P Q P P SP + Q A+ V + + P PP + P PP+
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
P+ PP + PP AA PP P + + PPP P P+ PP +PPP P
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 427 SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPP 486
+ T LQ++ G P + P A LP P PP PP
Sbjct: 522 ALAT--------------PPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPV 565
Query: 487 VPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPAS 544
+ P PP PT P PPT P+ PRL T A+ P PPP P+S
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL--TLALAPGPPPPPSRSPSS 621
Score = 99.0 bits (245), Expect = 1e-20
Identities = 90/330 (27%), Positives = 118/330 (35%), Gaps = 52/330 (15%)
Query: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQ--KDPQQPAQQQQPAQQPKKP 323
P TP + P+L P P S PS + + P P + Q A
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPS-PSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341
Query: 324 SPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH-----PPLPPAHPPPDRKPPL 378
P PS+P ++ + SP + P ++ TH PPL P PP + PP
Sbjct: 342 PPSPSAPPSLQ--TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399
Query: 379 AAALGEAEPPGPVDATDLPKVQIPPPAHP---------APVHQPPPLPHRPPPPPPSSYM 429
A PP P + L + P P P AP PP P + P PP+S
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 430 TGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAY---GPPAHLPYHPHVYPPNPPPPP 486
S T ++ P A PP PPA P P PP PPP
Sbjct: 460 VSPSATPP---------------SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 487 VPPPPASF--PPPAIPP-----PTPGYPPPPPTY--------NPNFPPPPPRLPPTHAVP 531
+ PP PPP PP P P PP ++ + + P P PP A P
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 532 PHPPPGLGLPPASYPPPAVPPGGQPPVPPP 561
P L +PP+ P + +PP P P
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594
Score = 91.7 bits (226), Expect = 2e-18
Identities = 102/349 (29%), Positives = 119/349 (34%), Gaps = 78/349 (22%)
Query: 257 LYSQGKQQMPHHTPH------QLQQP-PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ 309
L SQ +P TPH QL P P P+P P Q+ PS + P
Sbjct: 313 LQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371
Query: 310 PAQQQQPAQQPKKP-SPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP-- 366
P Q + P P SP + P Q A+ + P + A P PP P + P P
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQA 427
Query: 367 -----------PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP 415
P PPP PP+ A P PV + P Q PP AP Q PP
Sbjct: 428 PNALAVHLLQAPFSPPPS--PPVQAPFSPPASP-PVSPSATPPSQAPPSL-AAPPLQVPP 483
Query: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHP 475
P PP PS+ + P A PP PPA
Sbjct: 484 SPPASPPMSPSATPPPQAPPPL---------------AAPPLQLAKPPPQAPPA------ 522
Query: 476 HVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA-----V 530
PP +P PPASFP A P+ P P PPP+ PP A V
Sbjct: 523 ---LATPPLQALPSPPASFPGQAPFSPSASLPMSP------LATPPPQAPPVLAAPLLQV 573
Query: 531 PPHPPPGLGLPPASYPPPAVPPGGQPPV----------PPPIPPPGMPP 569
PP PP L PP PG V P P PPP P
Sbjct: 574 PPSPPASPTLQAPRRPP---TPGPDTSVSGPRLTLALAPGPPPPPSRSP 619
Score = 78.6 bits (192), Expect = 1e-14
Identities = 83/295 (28%), Positives = 106/295 (35%), Gaps = 52/295 (17%)
Query: 276 PPSLQP-TPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVK 334
PP+ P +P Q+ PS ++ P Q P P P+ P P + P Q+
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 335 RAVVVSPKEENKAAEPPPPKIPKIETTHP-----------PLPPAHPPPDRKPPLAAALG 383
+ P+ A PP +P + P P+ P PP + PP+ AA
Sbjct: 514 KP---PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570
Query: 384 EAEPPGPVDATDLPKVQIPPPAHPAPVHQPP----PLPHRPPPPP---PSSYMTG----- 431
PP P + L + PP P P L PPPPP PSS ++G
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 432 --MSTTSSYMSGEGYQSLQSMMKTEGPSYGAL--PPAYGPPAHL-PYHPHVYPPNPPPP- 485
S TS+ GY S GP GA PP P A L HP + P PP
Sbjct: 631 HSSSATSTPEELRGYDS--------GPEGGAAASPP---PDAELAACHPAAWSRGPAPPL 679
Query: 486 ---PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
P P +PP P G T P P P A+ P P PG
Sbjct: 680 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP-----GALDPGPSPG 729
Score = 68.9 bits (167), Expect = 1e-11
Identities = 81/295 (27%), Positives = 107/295 (36%), Gaps = 48/295 (16%)
Query: 302 PQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE-- 359
P++ A++ P PSP + + V P+ A PP + P+
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 360 -----TTHPPLPPAHPPPDR----KPPLAAALGEAEPPGPVDATDLPKVQIPP--PAHPA 408
+T P P A P + P + +L + P A P + P PAHP+
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 409 PVHQPPPL---PHRPPP--PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
QP P RPP PP + SS S + T PS A
Sbjct: 271 ---QPKPKGLQALRPPQVTPPRKDAAPALGPLSS-----------SPLATPSPS--AALQ 314
Query: 464 AYGPPAHLPYHPHVYPPN----PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPP 519
+ PP LP PH P P PP P++ P P P PP T +
Sbjct: 315 SQAPPT-LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG--- 370
Query: 520 PPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPG-GQPPVPPPIPPPGMPPVGGL 573
P L TH+ P PP L P + PPP PP PP+ P PP PP+ L
Sbjct: 371 -SPTLQATHSFLPSPP----LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/292 (23%), Positives = 88/292 (30%), Gaps = 71/292 (24%)
Query: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPL-----AAALGE---AEPPGPVDATDLPK 398
AA P + P + T PP P PPP L A A+G AE G + +P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP- 71
Query: 399 VQIPPPAHPA---------PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE------G 443
+ P A P P +PP PP + G ++ SG G
Sbjct: 72 -ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 444 YQSLQSMMK--------TEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFP 495
+ L+ + TE P AL P P P P A+
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP-----TPGTPSPAMARRSRAAGT 185
Query: 496 PPAIPPPTPGYPPPPPTYNP------------NFPPPPPRLPP--------------THA 529
+P P P P PPT P P P R P + +
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 530 VPPHPPPGLGLPPA-------SYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
P P P A ++P P G Q PP + PP LG
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 114 bits (286), Expect = 2e-25
Identities = 103/340 (30%), Positives = 132/340 (38%), Gaps = 50/340 (14%)
Query: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332
LQ+P S + + S P++S ++ + P P+Q + Q +P PQ + PR+
Sbjct: 225 LQRPASRSLSSSATPL--SSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRK 281
Query: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVD 392
A + P + A P P P + PP P P PP A P
Sbjct: 282 -DAAPALGPLSSSPLATPSPSAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 393 ATDLPKVQIPPPAHPAPVHQP----PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQ 448
+ LP + P A P P P PPL PP PP S ++ ++T S L
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 449 SMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP--PAIPPPTPGY 506
+ PS P + PPA P P PP+ PP + PP PP PA PP +P
Sbjct: 398 QAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456
Query: 507 PPPPPTYNPNFPPP------PPRLPPTHAVPPHPPPGLGLPPASYP-------------- 546
PPP P PP PP+ PP A PP L PPAS+P
Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSASLPMS 514
Query: 547 PPAVPPGGQPPV-------PPPIPP-------PGMPPVGG 572
P A PP PPV PP PP P PP G
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554
Score = 110 bits (276), Expect = 3e-24
Identities = 100/349 (28%), Positives = 132/349 (37%), Gaps = 73/349 (20%)
Query: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPS 324
+P P +PP+ P V + ++EPS ++ P Q+PA + S
Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 325 PQP-SSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALG 383
P SSP + + +P+ A P PK ++ PP P D P L
Sbjct: 237 ATPLSSPARSGPSARGTPRAP---AHPSQPKPKGLQALRPP-QVTPPRKDAAPAL----- 287
Query: 384 EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP--PPSSYMTGMSTTSSYMSG 441
GP+ ++ L P P+ P PP L P PP PPS T + + +
Sbjct: 288 -----GPLSSSPLAT---PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT----- 334
Query: 442 EGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP------------------ 483
Q+ S + + S A PP PPA L P PP+PP
Sbjct: 335 --LQATHSFLPSPPLSPLATPPPQAPPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNA 391
Query: 484 -----------PPPVPPPPASFPPPAIPPPTPGYPPP---------PPTYNPNFPPPPPR 523
PPP PP A F PPA PP +P PP PP P PP P
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 451
Query: 524 LPPTHAVPPHPPPGLGLPP--ASYPPPAVPPG-GQPPVPP-PIPPPGMP 568
+ P+ PP PP L PP + PPP PP PP+ P PP P
Sbjct: 452 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500
Score = 105 bits (261), Expect = 1e-22
Identities = 89/298 (29%), Positives = 110/298 (36%), Gaps = 41/298 (13%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQS--------------SEPSQPQQKDPQQ--PAQQ 313
P PPSLQ P P SQ + S S P P P Q PA
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 314 QQPAQQPKKP------SPQPSSPRQVKRAVVVSPKEENKAAEPPPP-KIPKIETTHPPLP 366
P Q P P SP + Q A+ V + + P PP + P PP+
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422
Query: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
P+ PP + PP AA PP P + + PPP P P+ PP +PPP P
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Query: 427 SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPP 486
+ T LQ++ G P + P A LP P PP PP
Sbjct: 483 ALAT--------------PPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPV 526
Query: 487 VPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPAS 544
+ P PP PT P PPT P+ PRL T A+ P PPP P+S
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL--TLALAPGPPPPPSRSPSS 582
Score = 102 bits (253), Expect = 1e-21
Identities = 87/325 (26%), Positives = 115/325 (35%), Gaps = 57/325 (17%)
Query: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRA 336
PS + TP+ P + + +P Q P P + PA P SP + +
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP--PRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 337 VVVSPKEENKAAEPPPPKI--------PKIETTH-----PPLPPAHPPPDRKPPLAAALG 383
P + + P P P ++ TH PPL P PP + PP A
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 384 EAEPPGPVDATDLPKVQIPPPAHP---------APVHQPPPLPHRPPPPPPSSYMTGMST 434
PP P + L + P P P AP PP P + P PP+S S
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 435 TSSYMSGEGYQSLQSMMKTEGPSYGALPPAY---GPPAHLPYHPHVYPPNPPPPPVPPPP 491
T ++ P A PP PPA P P PP PPP+ PP
Sbjct: 426 TPP---------------SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 492 ASF--PPPAIPP-----PTPGYPPPPPTY--------NPNFPPPPPRLPPTHAVPPHPPP 536
PPP PP P P PP ++ + + P P PP A P P
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 537 GLGLPPASYPPPAVPPGGQPPVPPP 561
L +PP+ P + +PP P P
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGP 555
Score = 91.3 bits (225), Expect = 2e-18
Identities = 102/340 (30%), Positives = 119/340 (35%), Gaps = 69/340 (20%)
Query: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325
P TP + P+L P P S PS PS P P PA P + +
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPS-PSAPPSPSAP----PSLQTLPSPPATPPSQATT 328
Query: 326 QPSSPR-QVKRAVVVSPKEENKAAEPP--PPKIPKIETTHPPLPPAHPP------PDRKP 376
SP Q + + SP A PP PP + PP PPA PP P +
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 377 PLAAALGEAEPPGPVDATDLPKVQIP--PPAHPA-------PVHQPPPL---PHRPPPPP 424
P A A+ + P P VQ P PPA P P PP L P + PP P
Sbjct: 389 PNALAVHLLQ--APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446
Query: 425 PSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP 484
P+S S T + + P A PP PPA PP
Sbjct: 447 PASPPMSPSATPPPQAPPPLAA--------PPLQLAKPPPQAPPA---------LATPPL 489
Query: 485 PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA-----VPPHPPPGLG 539
+P PPASFP A P+ P P PPP+ PP A VPP PP
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSP------LATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 540 LPPASYPPPAVPPGGQPPV----------PPPIPPPGMPP 569
L PP PG V P P PPP P
Sbjct: 544 LQAPRRPP---TPGPDTSVSGPRLTLALAPGPPPPPSRSP 580
Score = 78.6 bits (192), Expect = 1e-14
Identities = 83/295 (28%), Positives = 106/295 (35%), Gaps = 52/295 (17%)
Query: 276 PPSLQP-TPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVK 334
PP+ P +P Q+ PS ++ P Q P P P+ P P + P Q+
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 335 RAVVVSPKEENKAAEPPPPKIPKIETTHP-----------PLPPAHPPPDRKPPLAAALG 383
+ P+ A PP +P + P P+ P PP + PP+ AA
Sbjct: 475 KP---PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531
Query: 384 EAEPPGPVDATDLPKVQIPPPAHPAPVHQPP----PLPHRPPPPP---PSSYMTG----- 431
PP P + L + PP P P L PPPPP PSS ++G
Sbjct: 532 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 432 --MSTTSSYMSGEGYQSLQSMMKTEGPSYGAL--PPAYGPPAHL-PYHPHVYPPNPPPP- 485
S TS+ GY S GP GA PP P A L HP + P PP
Sbjct: 592 HSSSATSTPEELRGYDS--------GPEGGAAASPP---PDAELAACHPAAWSRGPAPPL 640
Query: 486 ---PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
P P +PP P G T P P P A+ P P PG
Sbjct: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP-----GALDPGPSPG 690
Score = 70.5 bits (171), Expect = 4e-12
Identities = 80/326 (24%), Positives = 107/326 (32%), Gaps = 68/326 (20%)
Query: 293 PSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQP-SSPRQVKRAVVVSPKEENKAAEPP 351
P+++S P + + PA K SP P SSP + P +
Sbjct: 79 PTRTSRPPASGRGERAPPA---------KNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 352 PPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVH 411
+ + + T P K +A + GP T P + A V
Sbjct: 130 EETVARGKATEAP----------KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179
Query: 412 QPPPLPHRPPPPPPSSYMTGMSTTSSYMS-------------GEGYQSLQSMMKTEGPSY 458
P P P P PP +S+ S + + G G Q S + +
Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Query: 459 GALPPAYGPPAHLPYHPHVYPPNPPP-------PPVPPPPASFPPPAIPP--------PT 503
+ P GP A +P P P PP PP PA+ P P+
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 504 PGYPPPP--PTYNPNFPPPP-------------PRLPPTHAVPPHPPPGLGLPPASYPPP 548
P PP P P P PP P L TH+ P PP L P + PPP
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP----LSPLATPPP 355
Query: 549 AVPPG-GQPPVPPPIPPPGMPPVGGL 573
PP PP+ P PP PP+ L
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPL 381
Score = 45.1 bits (105), Expect = 2e-04
Identities = 67/283 (23%), Positives = 87/283 (30%), Gaps = 62/283 (21%)
Query: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPL-----AAALGE---AEPPGPVDATDLPK 398
AA P + P + T PP P PPP L A A+G AE G + +P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP- 71
Query: 399 VQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE------GYQSLQSMMK 452
+ P A P +PP PP + G ++ SG G + L+ +
Sbjct: 72 -ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 453 --------TEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP 504
TE P AL P P P P A+ +P P P
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGP-----TPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 505 GYPPPPPTYNP------------NFPPPPPRLPP--------------THAVPPHPPPGL 538
P PPT P P P R P + + P P
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 539 GLPPA-------SYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
P A ++P P G Q PP + PP LG
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 113 bits (283), Expect = 4e-25
Identities = 109/336 (32%), Positives = 124/336 (36%), Gaps = 65/336 (19%)
Query: 274 QQPPSL---QPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
++ PSL P PQ S P +PQ PQ Q Q P P KP P
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--- 82
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPK------IETTHPPLPPAHPPPDRKPPLAAALGE 384
P+ NK PPPP P+ ++ P PP P PP +
Sbjct: 83 ----------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG--KPQGPPPQGGNQPQ 130
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
PP P K Q PPP PPP P +P PPP S+ S +G
Sbjct: 131 GPPPPP------GKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGDNKSRSSRSPPGKPQG- 182
Query: 445 QSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP--PVPPPP--------ASF 494
Q + +GP PP G P P P PPPP P PPP A
Sbjct: 183 PPPQGGNQPQGP-----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 495 PP--PAIPPPTPG---YPPPPPTYNPNFPPP----PPRLPPTHAVPPHPPP-GLGLPPAS 544
PP P PPP G PPPP P PPP P+ PP P PPP G +S
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297
Query: 545 YPPPAVPPGGQP--------PVPPPIPPPGMPPVGG 572
PP P G P P PPP P G PP GG
Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 333
Score = 112 bits (279), Expect = 1e-24
Identities = 115/366 (31%), Positives = 127/366 (34%), Gaps = 88/366 (24%)
Query: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
GK Q P P Q P P P PQ Q +S P P K PQ P Q QP
Sbjct: 76 GKPQGP---PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQG--GNQP 129
Query: 321 KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPK----------IETTHPPLPPAHP 370
+ P P P P+ P+ NK PPPP P+ + PP P P
Sbjct: 130 QGPPPPPGKPQGPP------PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 371 PPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMT 430
PP G +P GP P Q PPP PPP P +P PPP
Sbjct: 184 PPQ---------GGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPP-PGKPQGPPPQGDNK 231
Query: 431 GMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVP-- 488
S S +G Q + +GP PP G P P P PPPP P
Sbjct: 232 SQSARSPPGKPQGPPP-QGGNQPQGP-----PPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285
Query: 489 ---------------------PPPASFPPPAIPPPTPGYP--PPPPTYN-PNFPPPP--P 522
PPP P PPP PG P PPP N P PPPP P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345
Query: 523 RLPPTH------------AVPPHPPPGLGLPPASYPPPA--------VPPGGQPPVPPPI 562
+ PP P PP G P PPPA PP GQP PP
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Query: 563 PPPGMP 568
P G P
Sbjct: 406 PQGGRP 411
Score = 111 bits (277), Expect = 2e-24
Identities = 108/336 (32%), Positives = 117/336 (34%), Gaps = 66/336 (19%)
Query: 263 QQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKK 322
Q P +Q Q PP PQ P Q Q P Q P Q + + P P K
Sbjct: 58 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK 117
Query: 323 PS-PQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPP--DRKPPLA 379
P P P Q + P K PPP K + PP P PPP D K
Sbjct: 118 PQGPPPQGGNQPQGP----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK---- 169
Query: 380 AALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYM 439
+ PPG K Q PPP PPP P +P PPP
Sbjct: 170 -SRSSRSPPG--------KPQGPPPQGGNQPQGPPPPPGKPQGPPPQG------------ 208
Query: 440 SGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP----PVPPPPASFP 495
G Q K +GP PP + P P PPP P PPP P
Sbjct: 209 -GNKPQGPPPPGKPQGP-----PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP---P 259
Query: 496 P--PAIPPPTPGYPP--PPPTYNPNFPPP-------PPRLPPTHAVPPHPPPGLGLPPAS 544
P P PPP G P PPP P PPP R PP P PPP G P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP--GKPQGPPPQGGNQPQG 317
Query: 545 YPPPAVPPGGQPP--------VPPPIPPPGMPPVGG 572
PPP P G PP PPP P G PP GG
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 353
Score = 85.9 bits (211), Expect = 9e-17
Identities = 84/293 (28%), Positives = 94/293 (32%), Gaps = 64/293 (21%)
Query: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKR 335
PP +P PQ S S P +PQ PQ Q Q P P KP P
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-------- 205
Query: 336 AVVVSPKEENKAAEPPPPKIPK----------IETTHPPLPPAHPPPDRKPPLAAALGEA 385
P+ NK PPPP P+ PP P PPP G
Sbjct: 206 -----PQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ---------GGN 251
Query: 386 EPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQ 445
+P GP P Q PPP PPP P +P PPP S+ S +G
Sbjct: 252 QPQGPPPPPGKP--QGPPPQGGNKPQGPPP-PGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 446 SLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP-------------------- 485
Q + +GP PP G P P P PPPP
Sbjct: 309 P-QGGNQPQGP-----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362
Query: 486 ---PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP 535
P PP P PPP G P P P P P PP P PP
Sbjct: 363 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 83.2 bits (204), Expect = 6e-16
Identities = 79/260 (30%), Positives = 87/260 (33%), Gaps = 58/260 (22%)
Query: 339 VSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPK 398
VS +E P P P PP+ P + PP G +P GP P
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPP---PQGGNQPQGPPPPPGKP- 78
Query: 399 VQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY 458
Q PPP PPP P +P PPP G+ +S +S
Sbjct: 79 -QGPPPQGGNKPQGPPP-PGKPQGPPPQ--------------GDKSRSPRS--------- 113
Query: 459 GALPPA--YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPP------ 510
PP GPP P PP P P PPP P PPP PPP
Sbjct: 114 ---PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 170
Query: 511 -----PTYNPNFPPP-----PPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPG------- 553
P P PPP P PP P PPP G P PPP P G
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230
Query: 554 -GQPPVPPPIPPPGMPPVGG 572
Q PP P G PP GG
Sbjct: 231 KSQSARSPPGKPQGPPPQGG 250
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/152 (37%), Positives = 62/152 (40%), Gaps = 34/152 (22%)
Query: 448 QSMMKTEGPSYGALPPAYGPP--AHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPG 505
+ + + E PS A P PP + P P P+PP P PPP P PPP PG
Sbjct: 21 EDVSQEESPSLIAGNPQGAPPQGGNKPQGP----PSPPGKPQGPPPQGGNQPQGPPPPPG 76
Query: 506 YP--PPPPTYN-PNFPPPP---------------PRLPPTHAVPPHPPPGLGLPPASYPP 547
P PPP N P PPPP PR PP P PPP G P PP
Sbjct: 77 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQGGNQPQGPPP 134
Query: 548 PAVPPGGQPP--------VPPPIPPPGMPPVG 571
P P G PP PPP P G PP G
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/88 (35%), Positives = 34/88 (38%), Gaps = 14/88 (15%)
Query: 497 PAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQP 556
P++ P PP P PP PP P PPP G P PPP P G P
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPP------GKPQGPPPQGGNQPQGPPPPPGKPQGPP 82
Query: 557 PV--------PPPIPPPGMPPVGGLGRA 576
P PPP P G PP G R+
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRS 110
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 112 bits (281), Expect = 7e-25
Identities = 92/318 (28%), Positives = 118/318 (37%), Gaps = 26/318 (8%)
Query: 240 QDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEP 299
Q + DV ++ ++ +G++ + P + PP +P + PQ P
Sbjct: 17 QSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPG-KPEGRPPQGGNQSQGPPPRP 75
Query: 300 SQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE 359
+P+ PQ Q Q P +P KP QP + P E PPP+
Sbjct: 76 GKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQG----PPPRPGKPEGPPPQGGNQS 131
Query: 360 TTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHR 419
PP P P+ PP + PP P K + PPP PPP P +
Sbjct: 132 QGPPPRPGK---PEGPPPQGGNQSQGPPPRP------GKPEGPPPQGGNQSQGPPPHPGK 182
Query: 420 PPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYP 479
P PPP EG Q +++GP P GPP+ P P
Sbjct: 183 PEGPPPQGGNQSQGPPPRPGKPEGPPP-QGGNQSQGPPPRPGKPE-GPPSQGGNKPQGPP 240
Query: 480 PNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLG 539
P+P P PPP P PPP PPPP NP P PPP A P PP
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPP------AGKPQGPP--- 291
Query: 540 LPPASYPPPAVPPGGQPP 557
PP P PP GQPP
Sbjct: 292 -PPPQGGRPHRPPQGQPP 308
Score = 29.6 bits (65), Expect = 8.0
Identities = 19/66 (28%), Positives = 24/66 (36%)
Query: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
GK Q P Q P PQ P P Q P + + P P Q +P + P
Sbjct: 244 GKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303
Query: 321 KKPSPQ 326
+ PQ
Sbjct: 304 QGQPPQ 309
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 111 bits (277), Expect = 2e-24
Identities = 108/371 (29%), Positives = 141/371 (38%), Gaps = 77/371 (20%)
Query: 256 DLYSQGKQQMPHHTPHQLQQPPSLQPTPQ-----VPQVQQSQPSQSSEPSQPQQKDPQQP 310
D S +QQM P LQ P + P P PQ+ P+ S+ PQ P
Sbjct: 170 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----P 225
Query: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA-- 368
Q P Q +P P + +++A + P+ PP P P + HPPL P
Sbjct: 226 TASQAPNQPQAPTAPVPHT--HIQQAPALHPQR------PPSPHPPPHPSPHPPLQPLTG 277
Query: 369 -----HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP- 422
P +PPL PPGP P +Q P P P P PP P
Sbjct: 278 SAGQPSAPSHAQPPLHGQ----GPPGPHSLQAGPLLQHPGP--PQPFGLPPQASQGQAPL 331
Query: 423 --PPPSSYM-TGMSTTSSYMSGEGYQSLQ---------SMMKTEGPSYGALPPAYGPPAH 470
P ++Y T + +S + + Q + +M + P +P P AH
Sbjct: 332 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 391
Query: 471 LPYHPHVYPPNP-------PPPPVPPPPASF----PPPAIPPPT---------PGYPPPP 510
+ PH+ P+P PPPP P +S PP A PPP P P P
Sbjct: 392 -KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 450
Query: 511 P--TYNPNFPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
P T + N PPPP PPT H V P PP + PGG PP+ PP P
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPP---------FAQHPFVPGGPPPITPPTCPST 501
Query: 567 MPPVGGLGRAA 577
P G G +A
Sbjct: 502 STPPAGPGTSA 512
Score = 92.8 bits (229), Expect = 8e-19
Identities = 103/354 (29%), Positives = 126/354 (35%), Gaps = 71/354 (20%)
Query: 283 PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPK 342
P P + + S S + DP+ Q + P PSPQ + A +
Sbjct: 123 PNSPSEGEGESSDSRSVNDEGSSDPKD-IDQDNRSTSPSIPSPQDNESDSDSSA-----Q 176
Query: 343 EENKAAEPPPPKIPKIETTHP-PLPPAHP--PPDRKPPLAAALGEAEPPGPVDATDLPKV 399
++ A+PP + P T P PP P P P A A+ P A + P+
Sbjct: 177 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
Query: 400 QIPPPAH------PAPVHQPPPLPHRPP---PPPPSSYMTGMSTTSSYMS---------- 440
P H PA Q PP PH PP P PP +TG + S S
Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
Query: 441 GEGYQSLQS--MMKTEGP----------SYGALPPAYGPPAHLPYHPHVYPPN------- 481
G SLQ+ +++ GP S G P P A P+ P +
Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
Query: 482 PPPPPVPPPPASFPPPAI-PPPTPGYP----------------PPPPTYNPNFPPPPPRL 524
PP P PPA P I PPPT P P P + N N PPPP
Sbjct: 357 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 416
Query: 525 P----PTHAVPPHPPPGLGLPPASYP---PPAVPPGGQPPVPPPIPPPGMPPVG 571
P TH P PP L L P S P PA PPG P PP PP G
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 470
Score = 74.7 bits (182), Expect = 2e-13
Identities = 79/258 (30%), Positives = 95/258 (36%), Gaps = 47/258 (18%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
PH Q P+ Q Q Q + QP + + P K P Q PA Q K P S
Sbjct: 340 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399
Query: 330 PRQVKRAVVVSPKEENKAAEPPPPKIP--KIETTHPPLPPAHPPPDRKPPLAAAL--GEA 385
P SP N PPP P + T HPP AHPPP + P + L A
Sbjct: 400 P---------SPFSMNANLPPPPALKPLSSLSTHHPP--SAHPPPLQLMPQSQPLPSSPA 448
Query: 386 EPPGPVDATDLPKVQIPPPAH--PAPVHQPPPLP------HRPPPPPPSSYMTGMSTTSS 437
+PPG + +LP PPPA P +HQ P P P PPP + T ST++
Sbjct: 449 QPPGLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 504
Query: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP- 496
GP A PP G A + P P V +
Sbjct: 505 ---------------PAGPGTSAQPPCSGAAAS--GGSIAGGSSCPLPTVQIKEEALDDA 547
Query: 497 --PAIPPPTPGYPPPPPT 512
P PPP P P P PT
Sbjct: 548 EEPESPPPPPRSPSPEPT 565
Score = 54.7 bits (130), Expect = 2e-07
Identities = 48/179 (26%), Positives = 61/179 (34%), Gaps = 18/179 (10%)
Query: 264 QMPHHTPH-----------QLQQPPSLQPTPQV----PQVQQSQPSQSSEPSQPQQKDPQ 308
Q H PH L PP+L+P + P P Q SQP P
Sbjct: 389 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
Query: 309 QPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA 368
QP Q P P+ P P + + P ++ PP I PPA
Sbjct: 449 QPPGLTQSQNLPPPPASHP--PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 506
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-HPAPVHQPPPLPHRPPPPPPS 426
P +PP + A + LP VQI A A + PP P R P P P+
Sbjct: 507 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 565
Score = 35.4 bits (80), Expect = 0.14
Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 81/338 (23%)
Query: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348
++ + + E + ++++ ++ A+ A + + PQ S P ++ + P AA
Sbjct: 630 REKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF--EPPPTTIAA 687
Query: 349 EPP--PPKIPKIET-THPPLPPAHPPPDRKPPLAAALGEAEP------PG--PVDAT--- 394
PP P P + T + P P +R P L +P PG VD T
Sbjct: 688 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 747
Query: 395 -DLPKVQI---------------------PP---PAHPA--PV-----HQPPPLPHRPPP 422
+L + +I PP P HPA P+ H +P P
Sbjct: 748 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 807
Query: 423 PPPSSYMTGMSTTS---------------SY---MSGEGYQSLQSMMKTEGP----SYGA 460
P +S+ G++ SY ++ E + + T P
Sbjct: 808 HPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFN 867
Query: 461 LPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
+ P + +H+ H H++ +P + A P + P T G + FP P
Sbjct: 868 VTPHHHQHSHIHSHLHLHQQDP----LHQGSAGPVHPLVDPLTAG------PHLARFPYP 917
Query: 521 PPRLP-PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPP 557
P LP P PPH L P P P PG PP
Sbjct: 918 PGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPP 955
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 111 bits (277), Expect = 2e-24
Identities = 108/371 (29%), Positives = 141/371 (38%), Gaps = 77/371 (20%)
Query: 256 DLYSQGKQQMPHHTPHQLQQPPSLQPTPQ-----VPQVQQSQPSQSSEPSQPQQKDPQQP 310
D S +QQM P LQ P + P P PQ+ P+ S+ PQ P
Sbjct: 724 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----P 779
Query: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA-- 368
Q P Q +P P + +++A + P+ PP P P + HPPL P
Sbjct: 780 TASQAPNQPQAPTAPVPHT--HIQQAPALHPQR------PPSPHPPPHPSPHPPLQPLTG 831
Query: 369 -----HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP- 422
P +PPL PPGP P +Q P P P P PP P
Sbjct: 832 SAGQPSAPSHAQPPLHGQ----GPPGPHSLQAGPLLQHPGP--PQPFGLPPQASQGQAPL 885
Query: 423 --PPPSSYM-TGMSTTSSYMSGEGYQSLQ---------SMMKTEGPSYGALPPAYGPPAH 470
P ++Y T + +S + + Q + +M + P +P P AH
Sbjct: 886 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 945
Query: 471 LPYHPHVYPPNP-------PPPPVPPPPASF----PPPAIPPPT---------PGYPPPP 510
+ PH+ P+P PPPP P +S PP A PPP P P P
Sbjct: 946 -KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 511 P--TYNPNFPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
P T + N PPPP PPT H V P PP + PGG PP+ PP P
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPP---------FAQHPFVPGGPPPITPPTCPST 1055
Query: 567 MPPVGGLGRAA 577
P G G +A
Sbjct: 1056 STPPAGPGTSA 1066
Score = 92.8 bits (229), Expect = 8e-19
Identities = 103/354 (29%), Positives = 126/354 (35%), Gaps = 71/354 (20%)
Query: 283 PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPK 342
P P + + S S + DP+ Q + P PSPQ + A +
Sbjct: 677 PNSPSEGEGESSDSRSVNDEGSSDPKD-IDQDNRSTSPSIPSPQDNESDSDSSA-----Q 730
Query: 343 EENKAAEPPPPKIPKIETTHP-PLPPAHP--PPDRKPPLAAALGEAEPPGPVDATDLPKV 399
++ A+PP + P T P PP P P P A A+ P A + P+
Sbjct: 731 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790
Query: 400 QIPPPAH------PAPVHQPPPLPHRPP---PPPPSSYMTGMSTTSSYMS---------- 440
P H PA Q PP PH PP P PP +TG + S S
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 850
Query: 441 GEGYQSLQS--MMKTEGP----------SYGALPPAYGPPAHLPYHPHVYPPN------- 481
G SLQ+ +++ GP S G P P A P+ P +
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910
Query: 482 PPPPPVPPPPASFPPPAI-PPPTPGYP----------------PPPPTYNPNFPPPPPRL 524
PP P PPA P I PPPT P P P + N N PPPP
Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 970
Query: 525 P----PTHAVPPHPPPGLGLPPASYP---PPAVPPGGQPPVPPPIPPPGMPPVG 571
P TH P PP L L P S P PA PPG P PP PP G
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024
Score = 74.7 bits (182), Expect = 2e-13
Identities = 79/258 (30%), Positives = 95/258 (36%), Gaps = 47/258 (18%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
PH Q P+ Q Q Q + QP + + P K P Q PA Q K P S
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953
Query: 330 PRQVKRAVVVSPKEENKAAEPPPPKIP--KIETTHPPLPPAHPPPDRKPPLAAAL--GEA 385
P SP N PPP P + T HPP AHPPP + P + L A
Sbjct: 954 P---------SPFSMNANLPPPPALKPLSSLSTHHPP--SAHPPPLQLMPQSQPLPSSPA 1002
Query: 386 EPPGPVDATDLPKVQIPPPAH--PAPVHQPPPLP------HRPPPPPPSSYMTGMSTTSS 437
+PPG + +LP PPPA P +HQ P P P PPP + T ST++
Sbjct: 1003 QPPGLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058
Query: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP- 496
GP A PP G A + P P V +
Sbjct: 1059 ---------------PAGPGTSAQPPCSGAAAS--GGSIAGGSSCPLPTVQIKEEALDDA 1101
Query: 497 --PAIPPPTPGYPPPPPT 512
P PPP P P P PT
Sbjct: 1102 EEPESPPPPPRSPSPEPT 1119
Score = 54.7 bits (130), Expect = 2e-07
Identities = 48/179 (26%), Positives = 61/179 (34%), Gaps = 18/179 (10%)
Query: 264 QMPHHTPH-----------QLQQPPSLQPTPQV----PQVQQSQPSQSSEPSQPQQKDPQ 308
Q H PH L PP+L+P + P P Q SQP P
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 309 QPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA 368
QP Q P P+ P P + + P ++ PP I PPA
Sbjct: 1003 QPPGLTQSQNLPPPPASHP--PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-HPAPVHQPPPLPHRPPPPPPS 426
P +PP + A + LP VQI A A + PP P R P P P+
Sbjct: 1061 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 1119
Score = 35.4 bits (80), Expect = 0.14
Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 81/338 (23%)
Query: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348
++ + + E + ++++ ++ A+ A + + PQ S P ++ + P AA
Sbjct: 1184 REKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF--EPPPTTIAA 1241
Query: 349 EPP--PPKIPKIET-THPPLPPAHPPPDRKPPLAAALGEAEP------PG--PVDAT--- 394
PP P P + T + P P +R P L +P PG VD T
Sbjct: 1242 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 1301
Query: 395 -DLPKVQI---------------------PP---PAHPA--PV-----HQPPPLPHRPPP 422
+L + +I PP P HPA P+ H +P P
Sbjct: 1302 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 1361
Query: 423 PPPSSYMTGMSTTS---------------SY---MSGEGYQSLQSMMKTEGP----SYGA 460
P +S+ G++ SY ++ E + + T P
Sbjct: 1362 HPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFN 1421
Query: 461 LPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
+ P + +H+ H H++ +P + A P + P T G + FP P
Sbjct: 1422 VTPHHHQHSHIHSHLHLHQQDP----LHQGSAGPVHPLVDPLTAG------PHLARFPYP 1471
Query: 521 PPRLP-PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPP 557
P LP P PPH L P P P PG PP
Sbjct: 1472 PGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPP 1509
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 111 bits (277), Expect = 2e-24
Identities = 108/371 (29%), Positives = 141/371 (38%), Gaps = 77/371 (20%)
Query: 256 DLYSQGKQQMPHHTPHQLQQPPSLQPTPQ-----VPQVQQSQPSQSSEPSQPQQKDPQQP 310
D S +QQM P LQ P + P P PQ+ P+ S+ PQ P
Sbjct: 724 DSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS----P 779
Query: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA-- 368
Q P Q +P P + +++A + P+ PP P P + HPPL P
Sbjct: 780 TASQAPNQPQAPTAPVPHT--HIQQAPALHPQR------PPSPHPPPHPSPHPPLQPLTG 831
Query: 369 -----HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP- 422
P +PPL PPGP P +Q P P P P PP P
Sbjct: 832 SAGQPSAPSHAQPPLHGQ----GPPGPHSLQAGPLLQHPGP--PQPFGLPPQASQGQAPL 885
Query: 423 --PPPSSYM-TGMSTTSSYMSGEGYQSLQ---------SMMKTEGPSYGALPPAYGPPAH 470
P ++Y T + +S + + Q + +M + P +P P AH
Sbjct: 886 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 945
Query: 471 LPYHPHVYPPNP-------PPPPVPPPPASF----PPPAIPPPT---------PGYPPPP 510
+ PH+ P+P PPPP P +S PP A PPP P P P
Sbjct: 946 -KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 511 P--TYNPNFPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
P T + N PPPP PPT H V P PP + PGG PP+ PP P
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPP---------FAQHPFVPGGPPPITPPTCPST 1055
Query: 567 MPPVGGLGRAA 577
P G G +A
Sbjct: 1056 STPPAGPGTSA 1066
Score = 92.8 bits (229), Expect = 8e-19
Identities = 103/354 (29%), Positives = 126/354 (35%), Gaps = 71/354 (20%)
Query: 283 PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPK 342
P P + + S S + DP+ Q + P PSPQ + A +
Sbjct: 677 PNSPSEGEGESSDSRSVNDEGSSDPKD-IDQDNRSTSPSIPSPQDNESDSDSSA-----Q 730
Query: 343 EENKAAEPPPPKIPKIETTHP-PLPPAHP--PPDRKPPLAAALGEAEPPGPVDATDLPKV 399
++ A+PP + P T P PP P P P A A+ P A + P+
Sbjct: 731 QQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790
Query: 400 QIPPPAH------PAPVHQPPPLPHRPP---PPPPSSYMTGMSTTSSYMS---------- 440
P H PA Q PP PH PP P PP +TG + S S
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 850
Query: 441 GEGYQSLQS--MMKTEGP----------SYGALPPAYGPPAHLPYHPHVYPPN------- 481
G SLQ+ +++ GP S G P P A P+ P +
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910
Query: 482 PPPPPVPPPPASFPPPAI-PPPTPGYP----------------PPPPTYNPNFPPPPPRL 524
PP P PPA P I PPPT P P P + N N PPPP
Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 970
Query: 525 P----PTHAVPPHPPPGLGLPPASYP---PPAVPPGGQPPVPPPIPPPGMPPVG 571
P TH P PP L L P S P PA PPG P PP PP G
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTG 1024
Score = 74.7 bits (182), Expect = 2e-13
Identities = 79/258 (30%), Positives = 95/258 (36%), Gaps = 47/258 (18%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
PH Q P+ Q Q Q + QP + + P K P Q PA Q K P S
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953
Query: 330 PRQVKRAVVVSPKEENKAAEPPPPKIP--KIETTHPPLPPAHPPPDRKPPLAAAL--GEA 385
P SP N PPP P + T HPP AHPPP + P + L A
Sbjct: 954 P---------SPFSMNANLPPPPALKPLSSLSTHHPP--SAHPPPLQLMPQSQPLPSSPA 1002
Query: 386 EPPGPVDATDLPKVQIPPPAH--PAPVHQPPPLP------HRPPPPPPSSYMTGMSTTSS 437
+PPG + +LP PPPA P +HQ P P P PPP + T ST++
Sbjct: 1003 QPPGLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058
Query: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP- 496
GP A PP G A + P P V +
Sbjct: 1059 ---------------PAGPGTSAQPPCSGAAAS--GGSIAGGSSCPLPTVQIKEEALDDA 1101
Query: 497 --PAIPPPTPGYPPPPPT 512
P PPP P P P PT
Sbjct: 1102 EEPESPPPPPRSPSPEPT 1119
Score = 54.7 bits (130), Expect = 2e-07
Identities = 48/179 (26%), Positives = 61/179 (34%), Gaps = 18/179 (10%)
Query: 264 QMPHHTPH-----------QLQQPPSLQPTPQV----PQVQQSQPSQSSEPSQPQQKDPQ 308
Q H PH L PP+L+P + P P Q SQP P
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 309 QPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA 368
QP Q P P+ P P + + P ++ PP I PPA
Sbjct: 1003 QPPGLTQSQNLPPPPASHP--PTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA-HPAPVHQPPPLPHRPPPPPPS 426
P +PP + A + LP VQI A A + PP P R P P P+
Sbjct: 1061 GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 1119
Score = 35.4 bits (80), Expect = 0.14
Identities = 74/338 (21%), Positives = 118/338 (34%), Gaps = 81/338 (23%)
Query: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348
++ + + E + ++++ ++ A+ A + + PQ S P ++ + P AA
Sbjct: 1184 REKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSF--EPPPTTIAA 1241
Query: 349 EPP--PPKIPKIET-THPPLPPAHPPPDRKPPLAAALGEAEP------PG--PVDAT--- 394
PP P P + T + P P +R P L +P PG VD T
Sbjct: 1242 VPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRE 1301
Query: 395 -DLPKVQI---------------------PP---PAHPA--PV-----HQPPPLPHRPPP 422
+L + +I PP P HPA P+ H +P P
Sbjct: 1302 RELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGP 1361
Query: 423 PPPSSYMTGMSTTS---------------SY---MSGEGYQSLQSMMKTEGP----SYGA 460
P +S+ G++ SY ++ E + + T P
Sbjct: 1362 HPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFN 1421
Query: 461 LPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
+ P + +H+ H H++ +P + A P + P T G + FP P
Sbjct: 1422 VTPHHHQHSHIHSHLHLHQQDP----LHQGSAGPVHPLVDPLTAG------PHLARFPYP 1471
Query: 521 PPRLP-PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPP 557
P LP P PPH L P P P PG PP
Sbjct: 1472 PGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPP 1509
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 108 bits (269), Expect = 2e-23
Identities = 69/183 (37%), Positives = 80/183 (43%), Gaps = 23/183 (12%)
Query: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
VDA+ P PPP + P PPPP+ + + SG S+
Sbjct: 241 VDASSYP----PPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRG--SGLAGPKRSSV 294
Query: 451 MKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP----TPGY 506
+ P PP PP P + P P PPP PPP PPP PPP +PG
Sbjct: 295 VSPSHPP--PAPPLGSPPGPKPG----FAPPPAPPPPPPPMIGIPPP--PPPVGFGSPGT 346
Query: 507 PPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
PPPP P+FPP P P PP PPP P PP + P GG PP PPP PPPG
Sbjct: 347 PPPPSP--PSFPPHPDFAAPP---PPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401
Query: 567 MPP 569
PP
Sbjct: 402 PPP 404
Score = 100 bits (249), Expect = 4e-21
Identities = 83/283 (29%), Positives = 96/283 (33%), Gaps = 103/283 (36%)
Query: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
P QS + S PS + P PA+ P + S KR+ VVSP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRG-----SGLAGPKRSSVVSPSHP- 300
Query: 346 KAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA 405
PP PP PP KP A PPPA
Sbjct: 301 -----------------PPAPPLGSPPGPKPGFA----------------------PPPA 321
Query: 406 HPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAY 465
P P PPP+ PPPPPP + G T PP
Sbjct: 322 PPPP---PPPMIGIPPPPPPVGF--GSPGT--------------------------PPPP 350
Query: 466 GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525
PP+ P+ PP PPPPP P + PPP + PT G PPPPP PPPPP P
Sbjct: 351 SPPSFPPHPDFAAPPPPPPPPAADYP-TLPPPPLSQPTGGAPPPPP------PPPPPGPP 403
Query: 526 PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMP 568
PPP GQP +PPP+ P
Sbjct: 404 --------------------PPPFTGADGQPAIPPPLSDTTKP 426
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Query: 478 YPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
YPP P P SF +PPP + P + P R P P P
Sbjct: 246 YPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305
Query: 538 LGLPPASYPPPAVPPGGQPPVPPPIP-PPGMPPVG 571
LG PP P A PP PP PP I PP PPVG
Sbjct: 306 LGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVG 340
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/131 (26%), Positives = 40/131 (30%), Gaps = 21/131 (16%)
Query: 276 PPSLQPTPQVPQVQQSQPSQ----SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPR 331
PP P P P + P S + P P P A P P P P
Sbjct: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPT 377
Query: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPV 391
PPPP PP PP PP PP A G+ P P+
Sbjct: 378 L-----------------PPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
Query: 392 DATDLPKVQIP 402
T PK +P
Sbjct: 421 SDTTKPKSSLP 431
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 108 bits (269), Expect = 2e-23
Identities = 99/317 (31%), Positives = 123/317 (38%), Gaps = 35/317 (11%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQ------QPAQQPKKP 323
P Q PP QPTP +PQV QP +P P PA Q +P Q P+ P
Sbjct: 726 PPGQQPPPLAQPTP-LPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAP 784
Query: 324 -SPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIET-THPPLPPAH--PPPDRKPPLA 379
P P Q+ VV P + PP +P + T T PP+PP P P LA
Sbjct: 785 LQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA 844
Query: 380 AALGEAEPPGPVDATDLPKVQIPPPAHPAPV---HQPPPLPHRPPPPPPSSYMTGMSTTS 436
A L A P P+ A LP P A P + P +P PP + ++ S +
Sbjct: 845 APLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVA 904
Query: 437 SYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNP--------PPPPVP 488
Y + M +PP+ P H + PP P PP PV
Sbjct: 905 QLPGQPVYPAAFPQMAPTD-----VPPS---PHHTVQNMRATPPQPALPPQPTLPPQPVL 956
Query: 489 PPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP--ASYP 546
PP + PP + PP P PP P PP P LPP A+P P P L P
Sbjct: 957 PPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEP---LQPHLPEQA 1013
Query: 547 PPAVPPGGQPPVPPPIP 563
PA PG Q + P P
Sbjct: 1014 APAATPGSQILLGHPAP 1030
Score = 79.0 bits (193), Expect = 1e-14
Identities = 91/324 (28%), Positives = 111/324 (34%), Gaps = 69/324 (21%)
Query: 276 PPSLQ---PTPQVPQVQQSQPSQSSEPSQPQQKDP--QQPAQQQQPAQQPKKPSPQPSSP 330
PPSLQ P P + P + P+ P Q P QQP QP P+ +PQP P
Sbjct: 692 PPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVP 751
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP--PPDRKPPLAAALGEAEPP 388
Q P PP +P P L PA P + PL +P
Sbjct: 752 LQ-----------------PVPPHLP------PYLAPASQVGAPAQLKPLQMPQAPLQPL 788
Query: 389 GPVDATDLPKVQIPPPAHPAPVHQ--PPPLPHRP----PPPPPSSYMTGMSTTSSYMSGE 442
V +P + + PP P PP LP P PP PP Y +
Sbjct: 789 AQVPP-QMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVI-------- 839
Query: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP 502
L S+ P+ ALP LP+ P P VP PA+ P A+ PP
Sbjct: 840 ----LPSLAAPLPPASPALPLQ---AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPP 892
Query: 503 ----------------TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYP 546
P YP P P PP P + P P L P P
Sbjct: 893 GVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPP 952
Query: 547 PPAVPPGGQPPVPPPIPP-PGMPP 569
P +PP P P +PP P PP
Sbjct: 953 QPVLPPQPTLPPQPVLPPQPTRPP 976
Score = 75.5 bits (184), Expect = 1e-13
Identities = 92/343 (26%), Positives = 119/343 (34%), Gaps = 59/343 (17%)
Query: 260 QGKQQMPHHTPHQLQQPPSLQPTPQVP-QVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQ 318
Q K+Q +P + + PP VP QVQ + +Q+ +P P+ ++P+ P
Sbjct: 551 QPKEQQDVGSPDKARGPP-------VPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL 603
Query: 319 QPKKPSPQPSSPRQVKRAVVVSPKEENKA----------AEPPPPKIPKIETTHPPLPPA 368
S S + V ++ A P P + PP+
Sbjct: 604 PTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQC----VCSPPVSEG 659
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQ---PPPLPHRPPPPPP 425
P P L A PG LP +P PA P + Q P + P PPP
Sbjct: 660 PVLPQSLPSLGAYQQPTAAPG------LPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPP 713
Query: 426 SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGA---LPPAYGPPAHLPYHPHVYPPNP 482
S T M T + G Q T P A + P P HLP P++ P +
Sbjct: 714 S---TPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP--PYLAPASQ 768
Query: 483 PPPPVPPPPASFPPPAIPP--PTPGYPPPPPTYNPNFPPP-----PPRLP--PTHAVPPH 533
P P P + P P PP P P P PP LP PT VPP
Sbjct: 769 VGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPV 828
Query: 534 PPPGLGLPPASYPPPAVPPGGQPPVPPPIP--------PPGMP 568
PPP P P A P PP P +P PPG P
Sbjct: 829 PPPQYFSPAVILPSLAAP---LPPASPALPLQAVKLPHPPGAP 868
Score = 70.5 bits (171), Expect = 4e-12
Identities = 78/252 (30%), Positives = 93/252 (36%), Gaps = 72/252 (28%)
Query: 387 PPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEG--- 443
PP P+ Q P P P +P H PP P+S T +++ S++ SG+G
Sbjct: 567 PPVPLQVQVTYHAQAGQPGPPEP-EEPEADQHLLPPTLPTS-ATSLASDSTFDSGQGSTV 624
Query: 444 ----YQSLQSMMK-------------------TEGPSYGALPP---AYGPPAHLPYHPHV 477
S QS+M +EGP P AY P P P
Sbjct: 625 YSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVG 684
Query: 478 YPPNPPPPP-----VPPPPASF----PPPAIPPPT-PGYPPPPPTYNPNFPPPPPRLP-- 525
P P PP P P SF PPP+ P PT PG P PP P P P LP
Sbjct: 685 SVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP-LPQV 743
Query: 526 -------PTHAVPPHPPPGLG---------------LPPASYPPPAVPPGGQPPVP--PP 561
P VPPH PP L +P A P A P PP+P PP
Sbjct: 744 LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP 803
Query: 562 IPP----PGMPP 569
I P G+PP
Sbjct: 804 ITPLAGIDGLPP 815
Score = 68.6 bits (166), Expect = 2e-11
Identities = 75/265 (28%), Positives = 97/265 (36%), Gaps = 31/265 (11%)
Query: 313 QQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPP 372
++ Q P Q + KR ++ P AE P P+ P+ + PPLP + PP
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICP-----VAEHPAPEAPE---SSPPLPLSSLPP 1340
Query: 373 DRKP---PLAAALGEAEPPGPVDATDLPKV---QIPPPAHPAPVHQPPP----LPHRPPP 422
+ P L E P + + L PP A PAP+ P LP
Sbjct: 1341 EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAA 1400
Query: 423 PPPSSYMTGMSTTSSYMSGEGY-QSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN 481
P S+ S T+S G G Q L S ++T P P A P + P
Sbjct: 1401 PATSTMPEPASGTASQAGGPGTPQGLTSELETSQP---LAETHEAPLAVQPLVVGLAPCT 1457
Query: 482 PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVP-------PHP 534
P P AS P +PPP P P T P P P LP P P
Sbjct: 1458 PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
Query: 535 PPGLGLPPASYPPPAVPPGGQPPVP 559
P G +PP PP A+ G+ P P
Sbjct: 1518 PLGPTVPP--QPPSALESDGEGPPP 1540
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/232 (25%), Positives = 73/232 (31%), Gaps = 26/232 (11%)
Query: 317 AQQPKKPSPQPSSPRQVKRAVVVSPKE--ENKAAEPPPPKIPKIETTHPPLPPAHPPPDR 374
AQ P +P + P+ V SP +N A PP P +P + T PP P P P
Sbjct: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPP-QPTLPPQPVLPPQPTL 962
Query: 375 KPPLAAALGEAEPPGPVDATD--LPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGM 432
P PP PV LP + PP PV P PH P P++ G
Sbjct: 963 PPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA-TPGS 1021
Query: 433 STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP-------- 484
+ + + P L P P LP P + P P
Sbjct: 1022 QILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPL-PEVLLPAAPELLPQFPSSLATVSASV 1080
Query: 485 -----------PPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525
PP PP P A P PT P PP LP
Sbjct: 1081 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/177 (27%), Positives = 59/177 (33%), Gaps = 20/177 (11%)
Query: 402 PPPAHPAPV--HQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459
P HPAP PPLP PP S S + + Q ++ GPS
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN- 1375
Query: 460 ALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGY------PPPPPTY 513
P PPA L P +PP +P A+ +P P G P P
Sbjct: 1376 ---PPGAPPAPLA------PSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGL 1426
Query: 514 NPNFPPPPPRLPPTHAVPPHPPP-GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
P L TH P P +GL P + P A P+PPP P
Sbjct: 1427 TSELETSQP-LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEP 1482
Score = 43.1 bits (100), Expect = 7e-04
Identities = 45/181 (24%), Positives = 51/181 (28%), Gaps = 56/181 (30%)
Query: 449 SMMKTEGPSYGALPPAYGPPAHL----PYHPHVYPPNPPPPPVPPPPASFPPP------- 497
++ E G+ A GPP L YH P PP P P PP
Sbjct: 549 ALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSAT 608
Query: 498 ----------------------------------AIPPPTPGYPPPPPTYNPNFPPPPPR 523
A P P PP + P P P
Sbjct: 609 SLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPS 668
Query: 524 LPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPP-------IPPPGMPPVGGLGRA 576
L P GLP S P PA PP Q P P +PPP P G G+
Sbjct: 669 L----GAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQP 724
Query: 577 A 577
A
Sbjct: 725 A 725
Score = 42.4 bits (98), Expect = 0.001
Identities = 66/261 (25%), Positives = 81/261 (31%), Gaps = 58/261 (22%)
Query: 267 HHTPHQLQQPPSLQPTPQVPQVQQSQP---SQSSEPSQPQQKDPQQPAQQQQPAQQPKKP 323
H P + P L + P+ Q Q S QP QQ Q P+ P P
Sbjct: 1321 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1380
Query: 324 SPQ--PSSPR-----QVKRAVVVSPKEE------NKAAEPPPPK--IPKIETTHPPLPPA 368
PSSP Q A S E ++A P P+ ++ET+ P L
Sbjct: 1381 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQP-LAET 1439
Query: 369 HPPPDRKPPLAAALGEAEPPGPVDAT---DLPKVQIPPPAHPAPVHQPPPLPHRPPPPPP 425
H P PL L P +T P+ +PPPA P P PH P P
Sbjct: 1440 HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-------PEPSPHSGTPQPA 1492
Query: 426 SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP 485
G LP A G + L PP P
Sbjct: 1493 L----------------------------GQPAPLLPAAVGAVS-LATSQLPSPPLGPTV 1523
Query: 486 PVPPPPASFPPPAIPPPTPGY 506
P PP A PPP G+
Sbjct: 1524 PPQPPSALESDGEGPPPRVGF 1544
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 283 PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPK 342
P P++ PS + S Q P Q A PA P P +SP + + V P
Sbjct: 1060 PAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQ-LTVEPV 1118
Query: 343 EENKAAEPPPPKIPK 357
+E +A++ PP +P+
Sbjct: 1119 QEEQASQDKPPGLPQ 1133
Score = 34.3 bits (77), Expect = 0.32
Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 17/125 (13%)
Query: 310 PAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN---KAAEPPPPKIPK--------- 357
PA +P + +P PQ R ++R+VV S +EE +AAE P P+ P+
Sbjct: 23 PAGMAEPRAKAARPGPQ----RFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLL 78
Query: 358 IETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP-KVQIPPPAHPAPVHQPPPL 416
+T A P P A P P DA P Q P P A + P
Sbjct: 79 CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPA 138
Query: 417 PHRPP 421
P P
Sbjct: 139 PDGGP 143
Score = 33.9 bits (76), Expect = 0.42
Identities = 39/155 (25%), Positives = 58/155 (37%), Gaps = 33/155 (21%)
Query: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQ----QKDPQQPAQQQQPAQ---------- 318
L Q + T +P+ SQ+ P PQ + + QP + A
Sbjct: 1394 LPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGL 1453
Query: 319 QPKKPSPQPSS------PRQVKRAVVVSPKEENKAAEP----PPPKIP------KIETTH 362
P P+P+ +S PR+ P + +P P P +P + T+
Sbjct: 1454 APCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQ 1513
Query: 363 PPLPPAHPPPDRKPPLA-AALGEAEPP--GPVDAT 394
P PP P +PP A + GE PP G VD+T
Sbjct: 1514 LPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDST 1548
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 107 bits (266), Expect = 4e-23
Identities = 93/319 (29%), Positives = 126/319 (39%), Gaps = 73/319 (22%)
Query: 271 HQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
H+LQ + ++Q Q + + S+ QQ ++ + + +Q + +
Sbjct: 487 HELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKEL 546
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
K+ + + AA PP +P + P+PPA PP P
Sbjct: 547 EDAKKEMA----SLSAAAITVPPSVP----SRAPVPPA------------------PPLP 580
Query: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
D+ + IPPP P PPP P PPPPPP +S+ S G
Sbjct: 581 GDSGTI----IPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT-------- 628
Query: 451 MKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPP 510
A PP L + PPPPP+P P ++P T PPPP
Sbjct: 629 -------------AISPPPPLSGDATI----PPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671
Query: 511 PTYNPNFPPPPPRLPPTHAVPPHPPP---GLGLPPASYPPPAVPPG-GQPPVPP------ 560
+ PPPPP LP + +PP PPP G+PP PPP +P G G PP PP
Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPP---PPPPLPGGPGIPPPPPFPGGPG 728
Query: 561 -PIPPPGM----PPVGGLG 574
P PPPGM PP G G
Sbjct: 729 IPPPPPGMGMPPPPPFGFG 747
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 107 bits (266), Expect = 4e-23
Identities = 93/319 (29%), Positives = 126/319 (39%), Gaps = 73/319 (22%)
Query: 271 HQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
H+LQ + ++Q Q + + S+ QQ ++ + + +Q + +
Sbjct: 496 HELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKEL 555
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
K+ + + AA PP +P + P+PPA PP P
Sbjct: 556 EDAKKEMA----SLSAAAITVPPSVP----SRAPVPPA------------------PPLP 589
Query: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
D+ + IPPP P PPP P PPPPPP +S+ S G
Sbjct: 590 GDSGTI----IPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT-------- 637
Query: 451 MKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPP 510
A PP L + PPPPP+P P ++P T PPPP
Sbjct: 638 -------------AISPPPPLSGDATI----PPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680
Query: 511 PTYNPNFPPPPPRLPPTHAVPPHPPP---GLGLPPASYPPPAVPPG-GQPPVPP------ 560
+ PPPPP LP + +PP PPP G+PP PPP +P G G PP PP
Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPP---PPPPLPGGPGIPPPPPFPGGPG 737
Query: 561 -PIPPPGM----PPVGGLG 574
P PPPGM PP G G
Sbjct: 738 IPPPPPGMGMPPPPPFGFG 756
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 106 bits (264), Expect = 7e-23
Identities = 79/210 (37%), Positives = 88/210 (41%), Gaps = 49/210 (23%)
Query: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP---GPVDATDLPKVQIPPPAHP 407
PPP P +T PP PP PP PP G+ PP GP + D P PP P
Sbjct: 226 PPPPFPAGQT--PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP---PPVLFP 280
Query: 408 A-PVHQPP--PLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA 464
P QPP PLP PPPP P GY GP G PP
Sbjct: 281 GQPFGQPPLGPLPPGPPPPVP-----------------GY----------GPPPGPPPPQ 313
Query: 465 YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR- 523
GPP P +PP PP P + PP PPP +P P PG PPP P NP F PPP
Sbjct: 314 QGPPPP----PGPFPPRPPGP-LGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
Query: 524 -LPPTHAVPPHPPPGLGLPP----ASYPPP 548
+P + + P P G PP Y PP
Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
Score = 99.4 bits (246), Expect = 8e-21
Identities = 81/217 (37%), Positives = 88/217 (40%), Gaps = 49/217 (22%)
Query: 366 PPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPP 425
P A P DR P A G PP P T P+ + PP P P PPP PPP
Sbjct: 208 PGAVPGGDRFPGPAGP-GGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPP--- 262
Query: 426 SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP 485
++G P+ G PP PP P P PP P P
Sbjct: 263 -------------LAGP-------------PNRGDRPP---PPVLFPGQPFGQPPLGPLP 293
Query: 486 PVPPPPASF--PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH---PPPGLGL 540
P PPPP PPP PPP G PPPP + P PP P P T A PPH PPPG
Sbjct: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAP- 351
Query: 541 PPASYPPPAVPP----GGQPPV----PPPIPPPGMPP 569
PPA + PA P G P PPP P G PP
Sbjct: 352 PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388
Score = 37.0 bits (84), Expect = 0.050
Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 4/39 (10%)
Query: 535 PPGLGLPPASYPPPAVPPGGQPPVPPPIPP--PGMPPVG 571
P G G PP +P PP +PP+ PP PP PG PP G
Sbjct: 220 PAGPGGPPPPFPAGQTPP--RPPLGPPGPPGPPGPPPPG 256
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 106 bits (264), Expect = 7e-23
Identities = 96/280 (34%), Positives = 117/280 (41%), Gaps = 60/280 (21%)
Query: 318 QQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPP 377
++P P P+ P VKR PPPP + + PPLP + PPP PP
Sbjct: 215 EKPPAPPSLPAGPPGVKR--------------PPPPLMNGLPP-RPPLPESLPPP---PP 256
Query: 378 LAAALGEAEPPGPVDATDLPKVQIPPPAH----PAPVHQPPPLPHRPPPPPPSSYMTGMS 433
L P GP + Q+PPPA PAPV PP PP P G+
Sbjct: 257 GGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGV- 315
Query: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYG--PPAHLPYHPHVYPP----NPPPPPV 487
+ G S + P G PPA G PPA P V+PP +PP P V
Sbjct: 316 ----HPPAPGVHPPTSGVHPPAP--GVHPPAPGVHPPA-----PGVHPPAPGVHPPAPGV 364
Query: 488 -PPPPASFPP---------PAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP--HP- 534
PPP A P PA+ P PG PP P +P P P+ P H P HP
Sbjct: 365 HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQ 424
Query: 535 PPGL-GLPPASYPPPAVPPGGQPPVPPP----IPPPGMPP 569
PPG+ P +PP +PP +PP+P IPPP PP
Sbjct: 425 PPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPP--PP 462
Score = 89.7 bits (221), Expect = 6e-18
Identities = 84/275 (30%), Positives = 102/275 (37%), Gaps = 39/275 (14%)
Query: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPK 321
K + P P PP ++ P P + P + P P+ P P P P
Sbjct: 213 KMEKPPAPPSLPAGPPGVKRPP--PPLMNGLPPR---PPLPESLPPPPPGGLPLPPMPPT 267
Query: 322 KPSPQ--PSSPRQVKRAVVVSPKEENKAAEPPPPKI-PKIETTHPPLPPAHPP-PDRKPP 377
P+P P P+ A V P PP + P HPP P HPP P PP
Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAP--VVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP 325
Query: 378 LAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP---PPPSSYMTGMST 434
+ PP P P V P P VH P P H P P PPPS+ +
Sbjct: 326 TSGV----HPPAPGVHPPAPGVHPPAPG----VHPPAPGVHPPAPGVHPPPSAGV----- 372
Query: 435 TSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP-YHPHVYPPNPPPPPVPPPPAS 493
+ G + + P G PPA G P HP +P P V P P
Sbjct: 373 ---HPQAPGVHPAAPAVHPQAP--GVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPG 427
Query: 494 FPP--PAIPPPTPGYP---PPPPTYNP-NFPPPPP 522
P P + PPTP P PP P+ P N PPPPP
Sbjct: 428 VHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 87.4 bits (215), Expect = 3e-17
Identities = 71/205 (34%), Positives = 81/205 (39%), Gaps = 54/205 (26%)
Query: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMST 434
KPP +L P GP P V+ PPP + PPLP PPPPP
Sbjct: 216 KPPAPPSL----PAGP------PGVKRPPPPLMNGLPPRPPLPESLPPPPPG-------- 257
Query: 435 TSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNP---PPPPVPPPP 491
G +PP P+ P P + PP P PP PV PP
Sbjct: 258 --------------------GLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPP 297
Query: 492 ASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP 551
AS + PP PG PP P + PP P PPT V P P PG+ P PPA
Sbjct: 298 AS----GVHPPAPGVHPPAPGVH---PPAPGVHPPTSGVHP-PAPGVHPPAPGVHPPA-- 347
Query: 552 PGGQPPVP---PPIPPPGMPPVGGL 573
PG PP P PP P PP G+
Sbjct: 348 PGVHPPAPGVHPPAPGVHPPPSAGV 372
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/85 (40%), Positives = 39/85 (45%), Gaps = 25/85 (29%)
Query: 490 PPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPA 549
PPA PP++P PG PPP P + +PP PP P S PPP
Sbjct: 217 PPA---PPSLPAGPPGVKRPPP-------------PLMNGLPPRPPL-----PESLPPP- 254
Query: 550 VPPGGQPPVPPPIPPPGMPPVGGLG 574
PPGG P PP+PP G P G G
Sbjct: 255 -PPGGLPL--PPMPPTGPAPSGPPG 276
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 105 bits (263), Expect = 9e-23
Identities = 98/348 (28%), Positives = 122/348 (35%), Gaps = 62/348 (17%)
Query: 275 QPPS----LQPTPQVPQVQQSQPSQSSEPSQPQQKD----------PQQPAQQQQPAQQP 320
QPP +Q Q PQ ++ + S+PQ K P P+ + P QQP
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 321 KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAA 380
P P K P A+P P + PP PP KPP A
Sbjct: 310 TPGKPPAQQPGHEKS----QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQ 364
Query: 381 ALGEAEPPGPVDATDLPKVQIPPP---AHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSS 437
LG A+PP ++ P + P P A P V + P +P P P + G +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP--AQQPGPAKPPTQQVGTPKPLA 422
Query: 438 YMSGEGYQSLQSMMKTEGPSY--------GALPPAYGPPAHLPYHP--HVYPPNPPPPPV 487
G LQS K GP+ G +P P PP+ P P
Sbjct: 423 QQPG-----LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 488 PPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP---------PTHAVPPHPPPGL 538
PPP P PA PPP PP+ P PPP+ P P PP PG
Sbjct: 478 KPPPQQ-PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 539 GLPPASYPPPAVPP------------GGQPPVPPPIPPPG-MPPVGGL 573
P A P PA P G+P PP + P PP GL
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 67.8 bits (164), Expect = 3e-11
Identities = 81/354 (22%), Positives = 107/354 (30%), Gaps = 73/354 (20%)
Query: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ---PAQQQQPAQQPKKPSPQPSSP-- 330
P S QP + V + S P QPQQ P++ P Q A +PKKP P P
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSP-QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
A P E + ++P PPK P + + P A P + +
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 391 VDATDLPKVQIPPPAH-----------PAPVHQPPPLPHRPPP------PPPSSYMTGMS 433
D+P ++ A P PP + P P P+S +S
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS 493
+G + + + K E P + P A P P P PP
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA-----------KPMPKGSPTPPGP 881
Query: 494 FPPPAIPPPTPGYPPPPPTYNPNF----------PPPPPRLP------------------ 525
P PTP P P + F P P P
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 526 -----PTHAVP-PHPPPGLGLPPASYPPPAVPPGGQPP-----VPPPIPPPGMP 568
T P PH G G P P P+ PP Q P PP P +P
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995
Score = 67.8 bits (164), Expect = 3e-11
Identities = 55/184 (29%), Positives = 67/184 (36%), Gaps = 38/184 (20%)
Query: 424 PPSSY----MTGMSTTSSYMSGE--GYQSLQSMMKTEGPSYGALPPAYGP---PAHLPYH 474
PPSS M +T+ + SGE G + S + + PS +LP P + L
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 475 PHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPP-------- 526
PP PPPPP PPPP PPP +PPPT P P P P
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 527 -----------------THAVPPHPPPGLGLPP----ASYPPPAVPPGGQPPVPPPIPPP 565
T A PP PP +P P P+ PP PV P +P
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Query: 566 GMPP 569
P
Sbjct: 2523 TQKP 2526
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/179 (27%), Positives = 64/179 (35%), Gaps = 37/179 (20%)
Query: 257 LYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ-PAQQQQ 315
L S K P TP Q QP P QQ+ P ++S K P Q P +
Sbjct: 427 LQSPAKAPGPTKTPVQ-------QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479
Query: 316 PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRK 375
P QQP P P P K P + + PPP+ P PA P P +
Sbjct: 480 PPQQPGPAKPPPQQPGSAK------PPSQQPGSTKPPPQQP---------GPAKPSPQQP 524
Query: 376 PPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL-------PHRPPPPPPSS 427
G +PP + P Q P PA P+ P+ P +PP PS+
Sbjct: 525 -------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Score = 57.8 bits (138), Expect = 3e-08
Identities = 89/369 (24%), Positives = 112/369 (30%), Gaps = 73/369 (19%)
Query: 259 SQGKQQMPHHTPHQLQ---QPPSLQPTPQVPQVQQ--------SQPSQSSEPSQ---PQQ 304
+ +Q P P QL +PP QP P P QQ QP + P Q P +
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK 518
Query: 305 KDPQQPAQQQQPAQQP--KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH 362
PQQP + P+QQP KPS Q SP + P + + +P P
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 363 PP---LPPAHPPPDRKPPLAAALGEA---EPPGPVDATDLPKVQIPPPAHPAPVHQ---- 412
PP LP P L + E T P H V +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 413 -----------PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461
P+P P P T TT+S +S Q Q+ K +
Sbjct: 639 NCQMKRALGGDLAPVPSSPQP----KLKTAPVTTTSAVSKSSPQPQQTSPKKDA------ 688
Query: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA---IPPPTPGYPPPPPTYNPNFP 518
P L P P PPP V P P A PP P P P+ P
Sbjct: 689 ----APKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 519 PPPPRLPPTHAVPPHP---PPGLGLPPAS-------YPPPAVPPGGQPPVPPPI------ 562
+ P P P P L +S P V + PP+
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801
Query: 563 PPPGMPPVG 571
P PP G
Sbjct: 802 PSQSFPPTG 810
Score = 56.2 bits (134), Expect = 8e-08
Identities = 54/181 (29%), Positives = 71/181 (39%), Gaps = 21/181 (11%)
Query: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
PA P P +++ + P + D+ PPP P P PPP P PP PPP+
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 427 SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYH--PHVYPPNPPP 484
S + ++ S + T P + A+ A L + P P
Sbjct: 2432 SPKPTILPKKKL-------TVASPVTTATPLFDAVT-TLETTAVLRSNGLPVTRICTTAP 2483
Query: 485 PPVPPPPASFPPPAI--PPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP--HP-PPGLG 539
PPVPP P+S P + P P PP P P P+LP T P HP P GL
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAP------KPVIPQLPTTTQKPTDIHPKPTGLS 2537
Query: 540 L 540
L
Sbjct: 2538 L 2538
Score = 51.6 bits (122), Expect = 2e-06
Identities = 76/318 (23%), Positives = 110/318 (34%), Gaps = 42/318 (13%)
Query: 276 PPSLQPTPQVPQVQQSQ----PSQSSEPSQPQQKDPQQPAQQQQPA-----QQPKKPSPQ 326
PP+ +P + + Q+ P QS P P + P QP + + K P
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGR--PAQPGLSKSRTTDTFRSEQKLPGRS 129
Query: 327 PSSPRQVKRAVVVSPKEENKAAEPPP--PKIPKIETTHPPLPPAHPPPDRKPPLAAALGE 384
PS+ + KEE+K++ P ++ + + +P + +
Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNP--------FDLISD 181
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
+E + T KV P + +PP L +PP P P G + +
Sbjct: 182 SEA-SQEETTKKQKVVQKEQGKPEGIIKPP-LQQQPPKPIPKQQGPGRDPLQQDGTPKSI 239
Query: 445 QSLQ-SMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS--FPPPAIPP 501
S Q +K++ P G P GP P H P P + ++ P
Sbjct: 240 SSQQPEKIKSQPPGTGK--PIQGP-TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTH-------AVPPHPPPGLGLPPASYP----PPAV 550
P P PP P P PP P H A PP P GL P A P PP
Sbjct: 297 SLPS-PSKPPIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 551 PPGGQPPVPPPIPPPGMP 568
PPG P P+ P P
Sbjct: 355 PPGTTKPPAQPLGPAKPP 372
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/319 (23%), Positives = 102/319 (31%), Gaps = 73/319 (22%)
Query: 274 QQPPSLQPT------------PQVPQVQ-QSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
+QP ++PT P +P + QSQ + + P P + D +P+Q P +
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP--PLKTDSAKPSQSFPPTGEK 812
Query: 321 KKPSPQPSSPRQVKRAVVVS---PKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPP 377
P + PR + ++S P E+K + P + K E P PD KP
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKP- 870
Query: 378 LAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPP-----------PPPPS 426
G PPGP P P Q P P P S
Sbjct: 871 --MPKGSPTPPGPR----------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
Query: 427 SYMTGMSTTSSYMSGEG---YQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
T T + + G G + +++ T G P H P P
Sbjct: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQ----------PGPHSQSGPGA-PMKQA 967
Query: 484 PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPA 543
P P PP + PP + G PP P + P T A P L P
Sbjct: 968 PAPSQPPTSQG-----PPKSTGQAPPAPAKS------IPVKKETKA-----PAAEKLEPK 1011
Query: 544 SYPPPAVPPGGQPPVPPPI 562
+ P V PPPI
Sbjct: 1012 AEQAPTVKRTETEKKPPPI 1030
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/196 (25%), Positives = 74/196 (37%), Gaps = 25/196 (12%)
Query: 253 QILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQ 312
++L+ Y K+ T L + P V + + ++ + + ++PA
Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS 2374
Query: 313 QQQPAQQPKKPSPQPSSPRQVKRA--VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370
Q P+ P S P+ PR R+ + +S + PPPP P PPLPP
Sbjct: 2375 QL-PSGSPSVSS-LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 371 P-----PDRK----------PPLAAALGEAEPPGPVDATDLPKVQI----PPPAHPAPVH 411
P P +K PL A+ E + + LP +I PPP P P
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 412 QPPPL--PHRPPPPPP 425
P L HRP P P
Sbjct: 2493 IPSGLVFTHRPEPSKP 2508
Score = 39.7 bits (91), Expect = 0.008
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 5/53 (9%)
Query: 521 PPRLPPTHAVPPHPPP---GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
P P ++P P P L ++ PPP PP PP PPP PPP PP+
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP--PPPPPPPPPPPPPPPL 2427
Score = 39.3 bits (90), Expect = 0.010
Identities = 44/174 (25%), Positives = 56/174 (32%), Gaps = 55/174 (31%)
Query: 280 QPTPQVPQVQQSQPSQSSEP------------SQPQQKDPQQPAQQQQPAQQPKKPSPQP 327
+P Q+P S S ++P +QP P P P P P P P
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Query: 328 SSPRQV----KRAVVVSPKEENKAAEPPPPKIPKIETTH-----------------PPLP 366
+SP+ K+ V SP A P + +ETT PP+P
Sbjct: 2431 TSPKPTILPKKKLTVASPVT---TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 367 P-----------AHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409
P H P KPP+A P PV Q P HP P
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA--------PKPVIPQLPTTTQKPTDIHPKP 2533
Score = 38.5 bits (88), Expect = 0.017
Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 274 QQPPSLQPTPQVPQVQQSQPSQ---SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
Q P Q P P Q PSQ S P + + P PA+ ++ K P+ + P
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP---LP---PAHPPPDRKPPLAAA--- 381
+ + V + E K PPP K K T P LP P P+ PL
Sbjct: 1011 KAEQAPTVKRTETEKK---PPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067
Query: 382 LGEAEPP 388
+G +PP
Sbjct: 1068 IGSKDPP 1074
Score = 33.5 bits (75), Expect = 0.55
Identities = 33/131 (25%), Positives = 43/131 (32%), Gaps = 24/131 (18%)
Query: 294 SQSSEPSQPQQKDPQQPAQQ-QQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPP 352
S + +P Q P P +Q P+Q P P PK +A P
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP---------------PKSTGQAPPAPA 991
Query: 353 PKIP-KIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVH 411
IP K ET P P ++ P + E +PP D+ L A P
Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL-------TAEPQKAV 1044
Query: 412 QPPPLPHRPPP 422
P L P P
Sbjct: 1045 LPTKLEKSPKP 1055
Score = 30.8 bits (68), Expect = 3.6
Identities = 40/211 (18%), Positives = 69/211 (32%), Gaps = 30/211 (14%)
Query: 276 PPSLQPTPQ-VPQ--VQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332
PP + P P +P V +P S P P+ PQ P Q+P KP+ +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542
Query: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP--------PPDRKPPLAAALGE 384
V + K P P P + P + P + P ++ +
Sbjct: 2543 TLNLVT---SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP----------------HRPPPPPPSSY 428
A P+ + V + P P +P P PSS+
Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSF 2659
Query: 429 MTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459
++ + +++ E ++ S ++ PS G
Sbjct: 2660 QAAPTSVTQFLTTEVSKTEVSATRSTAPSVG 2690
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 105 bits (263), Expect = 9e-23
Identities = 98/348 (28%), Positives = 122/348 (35%), Gaps = 62/348 (17%)
Query: 275 QPPS----LQPTPQVPQVQQSQPSQSSEPSQPQQKD----------PQQPAQQQQPAQQP 320
QPP +Q Q PQ ++ + S+PQ K P P+ + P QQP
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 321 KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAA 380
P P K P A+P P + PP PP KPP A
Sbjct: 310 TPGKPPAQQPGHEKS----QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQ 364
Query: 381 ALGEAEPPGPVDATDLPKVQIPPP---AHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSS 437
LG A+PP ++ P + P P A P V + P +P P P + G +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP--AQQPGPAKPPTQQVGTPKPLA 422
Query: 438 YMSGEGYQSLQSMMKTEGPSY--------GALPPAYGPPAHLPYHP--HVYPPNPPPPPV 487
G LQS K GP+ G +P P PP+ P P
Sbjct: 423 QQPG-----LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 488 PPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP---------PTHAVPPHPPPGL 538
PPP P PA PPP PP+ P PPP+ P P PP PG
Sbjct: 478 KPPPQQ-PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 539 GLPPASYPPPAVPP------------GGQPPVPPPIPPPG-MPPVGGL 573
P A P PA P G+P PP + P PP GL
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 67.8 bits (164), Expect = 3e-11
Identities = 81/354 (22%), Positives = 107/354 (30%), Gaps = 73/354 (20%)
Query: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ---PAQQQQPAQQPKKPSPQPSSP-- 330
P S QP + V + S P QPQQ P++ P Q A +PKKP P P
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSP-QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
A P E + ++P PPK P + + P A P + +
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772
Query: 391 VDATDLPKVQIPPPAH-----------PAPVHQPPPLPHRPPP------PPPSSYMTGMS 433
D+P ++ A P PP + P P P+S +S
Sbjct: 773 TTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS 493
+G + + + K E P + P A P P P PP
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA-----------KPMPKGSPTPPGP 881
Query: 494 FPPPAIPPPTPGYPPPPPTYNPNF----------PPPPPRLP------------------ 525
P PTP P P + F P P P
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 526 -----PTHAVP-PHPPPGLGLPPASYPPPAVPPGGQPP-----VPPPIPPPGMP 568
T P PH G G P P P+ PP Q P PP P +P
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIP 995
Score = 67.8 bits (164), Expect = 3e-11
Identities = 55/184 (29%), Positives = 67/184 (36%), Gaps = 38/184 (20%)
Query: 424 PPSSY----MTGMSTTSSYMSGE--GYQSLQSMMKTEGPSYGALPPAYGP---PAHLPYH 474
PPSS M +T+ + SGE G + S + + PS +LP P + L
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 475 PHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPP-------- 526
PP PPPPP PPPP PPP +PPPT P P P P
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 527 -----------------THAVPPHPPPGLGLPP----ASYPPPAVPPGGQPPVPPPIPPP 565
T A PP PP +P P P+ PP PV P +P
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Query: 566 GMPP 569
P
Sbjct: 2523 TQKP 2526
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/179 (27%), Positives = 64/179 (35%), Gaps = 37/179 (20%)
Query: 257 LYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ-PAQQQQ 315
L S K P TP Q QP P QQ+ P ++S K P Q P +
Sbjct: 427 LQSPAKAPGPTKTPVQ-------QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479
Query: 316 PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRK 375
P QQP P P P K P + + PPP+ P PA P P +
Sbjct: 480 PPQQPGPAKPPPQQPGSAK------PPSQQPGSTKPPPQQP---------GPAKPSPQQP 524
Query: 376 PPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL-------PHRPPPPPPSS 427
G +PP + P Q P PA P+ P+ P +PP PS+
Sbjct: 525 -------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Score = 57.8 bits (138), Expect = 3e-08
Identities = 89/369 (24%), Positives = 112/369 (30%), Gaps = 73/369 (19%)
Query: 259 SQGKQQMPHHTPHQLQ---QPPSLQPTPQVPQVQQ--------SQPSQSSEPSQ---PQQ 304
+ +Q P P QL +PP QP P P QQ QP + P Q P +
Sbjct: 459 TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK 518
Query: 305 KDPQQPAQQQQPAQQP--KKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH 362
PQQP + P+QQP KPS Q SP + P + + +P P
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
Query: 363 PP---LPPAHPPPDRKPPLAAALGEA---EPPGPVDATDLPKVQIPPPAHPAPVHQ---- 412
PP LP P L + E T P H V +
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
Query: 413 -----------PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461
P+P P P T TT+S +S Q Q+ K +
Sbjct: 639 NCQMKRALGGDLAPVPSSPQP----KLKTAPVTTTSAVSKSSPQPQQTSPKKDA------ 688
Query: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA---IPPPTPGYPPPPPTYNPNFP 518
P L P P PPP V P P A PP P P P+ P
Sbjct: 689 ----APKQDLSKAPE---PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 519 PPPPRLPPTHAVPPHP---PPGLGLPPAS-------YPPPAVPPGGQPPVPPPI------ 562
+ P P P P L +S P V + PP+
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAK 801
Query: 563 PPPGMPPVG 571
P PP G
Sbjct: 802 PSQSFPPTG 810
Score = 56.2 bits (134), Expect = 8e-08
Identities = 54/181 (29%), Positives = 71/181 (39%), Gaps = 21/181 (11%)
Query: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
PA P P +++ + P + D+ PPP P P PPP P PP PPP+
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 427 SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYH--PHVYPPNPPP 484
S + ++ S + T P + A+ A L + P P
Sbjct: 2432 SPKPTILPKKKL-------TVASPVTTATPLFDAVT-TLETTAVLRSNGLPVTRICTTAP 2483
Query: 485 PPVPPPPASFPPPAI--PPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP--HP-PPGLG 539
PPVPP P+S P + P P PP P P P+LP T P HP P GL
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAP------KPVIPQLPTTTQKPTDIHPKPTGLS 2537
Query: 540 L 540
L
Sbjct: 2538 L 2538
Score = 51.6 bits (122), Expect = 2e-06
Identities = 76/318 (23%), Positives = 110/318 (34%), Gaps = 42/318 (13%)
Query: 276 PPSLQPTPQVPQVQQSQ----PSQSSEPSQPQQKDPQQPAQQQQPA-----QQPKKPSPQ 326
PP+ +P + + Q+ P QS P P + P QP + + K P
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGR--PAQPGLSKSRTTDTFRSEQKLPGRS 129
Query: 327 PSSPRQVKRAVVVSPKEENKAAEPPP--PKIPKIETTHPPLPPAHPPPDRKPPLAAALGE 384
PS+ + KEE+K++ P ++ + + +P + +
Sbjct: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNP--------FDLISD 181
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
+E + T KV P + +PP L +PP P P G + +
Sbjct: 182 SEA-SQEETTKKQKVVQKEQGKPEGIIKPP-LQQQPPKPIPKQQGPGRDPLQQDGTPKSI 239
Query: 445 QSLQ-SMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS--FPPPAIPP 501
S Q +K++ P G P GP P H P P + ++ P
Sbjct: 240 SSQQPEKIKSQPPGTGK--PIQGP-TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTH-------AVPPHPPPGLGLPPASYP----PPAV 550
P P PP P P PP P H A PP P GL P A P PP
Sbjct: 297 SLPS-PSKPPIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354
Query: 551 PPGGQPPVPPPIPPPGMP 568
PPG P P+ P P
Sbjct: 355 PPGTTKPPAQPLGPAKPP 372
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/319 (23%), Positives = 102/319 (31%), Gaps = 73/319 (22%)
Query: 274 QQPPSLQPT------------PQVPQVQ-QSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
+QP ++PT P +P + QSQ + + P P + D +P+Q P +
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP--PLKTDSAKPSQSFPPTGEK 812
Query: 321 KKPSPQPSSPRQVKRAVVVS---PKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPP 377
P + PR + ++S P E+K + P + K E P PD KP
Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKP- 870
Query: 378 LAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPP-----------PPPPS 426
G PPGP P P Q P P P S
Sbjct: 871 --MPKGSPTPPGPR----------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
Query: 427 SYMTGMSTTSSYMSGEG---YQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
T T + + G G + +++ T G P H P P
Sbjct: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQ----------PGPHSQSGPGA-PMKQA 967
Query: 484 PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPA 543
P P PP + PP + G PP P + P T A P L P
Sbjct: 968 PAPSQPPTSQG-----PPKSTGQAPPAPAKS------IPVKKETKA-----PAAEKLEPK 1011
Query: 544 SYPPPAVPPGGQPPVPPPI 562
+ P V PPPI
Sbjct: 1012 AEQAPTVKRTETEKKPPPI 1030
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/196 (25%), Positives = 74/196 (37%), Gaps = 25/196 (12%)
Query: 253 QILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQ 312
++L+ Y K+ T L + P V + + ++ + + ++PA
Sbjct: 2315 EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS 2374
Query: 313 QQQPAQQPKKPSPQPSSPRQVKRA--VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370
Q P+ P S P+ PR R+ + +S + PPPP P PPLPP
Sbjct: 2375 QL-PSGSPSVSS-LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS 2432
Query: 371 P-----PDRK----------PPLAAALGEAEPPGPVDATDLPKVQI----PPPAHPAPVH 411
P P +K PL A+ E + + LP +I PPP P P
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492
Query: 412 QPPPL--PHRPPPPPP 425
P L HRP P P
Sbjct: 2493 IPSGLVFTHRPEPSKP 2508
Score = 39.7 bits (91), Expect = 0.008
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 5/53 (9%)
Query: 521 PPRLPPTHAVPPHPPP---GLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
P P ++P P P L ++ PPP PP PP PPP PPP PP+
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP--PPPPPPPPPPPPPPPL 2427
Score = 39.3 bits (90), Expect = 0.010
Identities = 44/174 (25%), Positives = 56/174 (32%), Gaps = 55/174 (31%)
Query: 280 QPTPQVPQVQQSQPSQSSEP------------SQPQQKDPQQPAQQQQPAQQPKKPSPQP 327
+P Q+P S S ++P +QP P P P P P P P
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Query: 328 SSPRQV----KRAVVVSPKEENKAAEPPPPKIPKIETTH-----------------PPLP 366
+SP+ K+ V SP A P + +ETT PP+P
Sbjct: 2431 TSPKPTILPKKKLTVASPVT---TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 367 P-----------AHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409
P H P KPP+A P PV Q P HP P
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA--------PKPVIPQLPTTTQKPTDIHPKP 2533
Score = 38.5 bits (88), Expect = 0.017
Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 274 QQPPSLQPTPQVPQVQQSQPSQ---SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSP 330
Q P Q P P Q PSQ S P + + P PA+ ++ K P+ + P
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Query: 331 RQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPP---LP---PAHPPPDRKPPLAAA--- 381
+ + V + E K PPP K K T P LP P P+ PL
Sbjct: 1011 KAEQAPTVKRTETEKK---PPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067
Query: 382 LGEAEPP 388
+G +PP
Sbjct: 1068 IGSKDPP 1074
Score = 33.5 bits (75), Expect = 0.55
Identities = 33/131 (25%), Positives = 43/131 (32%), Gaps = 24/131 (18%)
Query: 294 SQSSEPSQPQQKDPQQPAQQ-QQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPP 352
S + +P Q P P +Q P+Q P P PK +A P
Sbjct: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP---------------PKSTGQAPPAPA 991
Query: 353 PKIP-KIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVH 411
IP K ET P P ++ P + E +PP D+ L A P
Sbjct: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL-------TAEPQKAV 1044
Query: 412 QPPPLPHRPPP 422
P L P P
Sbjct: 1045 LPTKLEKSPKP 1055
Score = 30.8 bits (68), Expect = 3.6
Identities = 40/211 (18%), Positives = 69/211 (32%), Gaps = 30/211 (14%)
Query: 276 PPSLQPTPQ-VPQ--VQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332
PP + P P +P V +P S P P+ PQ P Q+P KP+ +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542
Query: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP--------PPDRKPPLAAALGE 384
V + K P P P + P + P + P ++ +
Sbjct: 2543 TLNLVT---SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP----------------HRPPPPPPSSY 428
A P+ + V + P P +P P PSS+
Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSF 2659
Query: 429 MTGMSTTSSYMSGEGYQSLQSMMKTEGPSYG 459
++ + +++ E ++ S ++ PS G
Sbjct: 2660 QAAPTSVTQFLTTEVSKTEVSATRSTAPSVG 2690
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 105 bits (262), Expect = 1e-22
Identities = 79/231 (34%), Positives = 88/231 (38%), Gaps = 35/231 (15%)
Query: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
PPP + + P+ P KPP+ PP P P Q PPP P P
Sbjct: 34 PPPGMG-LNQNRGPMGPGPGQSGPKPPIP-------PPPPHQQQQQPPPQQPPPQQPPP- 84
Query: 411 HQPPPLPH----RPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYG 466
HQPPP P + PPPPP S+ G G P G+ PPA
Sbjct: 85 HQPPPHPQPHQQQQPPPPPQD-----SSKPVVAQGPG----------PAPGVGSAPPASS 129
Query: 467 --PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP---GYPPPPPTYNPNFPPPP 521
PPA P P P P PPP + PP PPPTP G P PP PPPP
Sbjct: 130 SAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP--QAGGPPPP 187
Query: 522 PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGG 572
P P P PG G P P PGG P + P P P GG
Sbjct: 188 PAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238
Score = 84.7 bits (208), Expect = 2e-16
Identities = 72/220 (32%), Positives = 77/220 (35%), Gaps = 67/220 (30%)
Query: 374 RKPPLAAALGEAEPP-GPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGM 432
R PP L + P GP PK IPPP QPPP +PPP P
Sbjct: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPP--QQPPPQQP------- 82
Query: 433 STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP--------- 483
P + PP H H PP PP
Sbjct: 83 ------------------------------PPHQPPPHPQPHQQQQPPPPPQDSSKPVVA 112
Query: 484 --PPPVP----PPPASFPPPAIPPPTPGYPP---PPPTYNPNFPPPPPRLPPTHAVPPHP 534
P P P PPAS P PPT G PP P PT P PP PP PP
Sbjct: 113 QGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP--PPAVTSAPP--GAPPPT 168
Query: 535 PPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLG 574
PP G+P PP A GG PP P +P PG P G G
Sbjct: 169 PPSSGVPTT--PPQA---GGPPPPPAAVPGPGPGPKQGPG 203
Score = 72.4 bits (176), Expect = 1e-12
Identities = 87/297 (29%), Positives = 96/297 (32%), Gaps = 93/297 (31%)
Query: 271 HQLQQPP-----SLQPTPQVPQVQQSQPSQSSEPSQP----QQKDPQQPAQQQQPAQQPK 321
H + PP + P P QS P P P QQ PQQP QQ P QP
Sbjct: 29 HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88
Query: 322 KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAA 381
P PQP +Q PPPP P KP +A
Sbjct: 89 -PHPQPHQQQQ-----------------PPPP----------------PQDSSKPVVAQG 114
Query: 382 LGEA-----EPPGPVDATDL--PKVQIPPPAHPAPVHQPPPL-----PHRPPPPPPSSYM 429
G A PP A P PP + P P PPP P PPP PPSS
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSS-- 172
Query: 430 TGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPP 489
G+ TT P G PP PPA +P P P P P
Sbjct: 173 -GVPTTP-------------------PQAGGPPP---PPAAVPGP----GPGPKQGPGPG 205
Query: 490 PPASFPPPAIPPP-------TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH--PPPG 537
P P P P TPG P PP P + P + H PPPG
Sbjct: 206 GPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262
Score = 70.5 bits (171), Expect = 4e-12
Identities = 70/238 (29%), Positives = 80/238 (33%), Gaps = 45/238 (18%)
Query: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
P Q P + P P P QQ QP P PQQ P QP QP QQ + P P S
Sbjct: 51 PGQSGPKPPIPPPP--PHQQQQQPPPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDS 106
Query: 330 PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG 389
+ V V P P P + PPA PP PP PG
Sbjct: 107 SKPV---VAQGPG--------PAPGVGSAPPASSSAPPATPPTSGAPP-------GSGPG 148
Query: 390 PVDATDLPKVQIPPPAHPAPVHQPPPLPHRP-----PPPPPSSYMTGMSTTSSYMSGEGY 444
P T P V PP P P +P P PPPPP++ + G G G
Sbjct: 149 PTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA-VPGPGPGPKQGPGPGG 206
Query: 445 QSLQSM-----------MKTEG-----PSYGALPPAYGPPAHLPYHPHVYPPNPPPPP 486
M + T G P G P G H PYH + PP P
Sbjct: 207 PKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 104 bits (259), Expect = 3e-22
Identities = 95/326 (29%), Positives = 114/326 (34%), Gaps = 48/326 (14%)
Query: 274 QQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQV 333
+Q P+L T P+ ++ P+ P+ P K P P+ + +P P
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 334 KRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP--PPDRKPPLAAALGEAEPPGPV 391
A SPK A P P P PP P P P + P A+ P G
Sbjct: 966 PAATPPSPK--GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 392 DATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMM 451
AT PK PPA PP P P P + ++ S +G
Sbjct: 1024 AATPFPKGASTPPA------ATPPSPKGSPAATPLPKGAPTTPAATLPSPKG-------- 1069
Query: 452 KTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP-----AIP-----P 501
GP+ +L A PPA P P P P P P PPA+ PP A P P
Sbjct: 1070 ---GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP---ASYPPPAVPPG----- 553
TP PP P PPP A PP P GL PP A P A PP
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 554 ------GQPPVPPPIPPPGMPPVGGL 573
G P P PP P GGL
Sbjct: 1187 ATPSPKGAPTTPAATPP---SPKGGL 1209
Score = 103 bits (256), Expect = 6e-22
Identities = 98/331 (29%), Positives = 117/331 (35%), Gaps = 36/331 (10%)
Query: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQ--PSQSSEPSQPQQKDPQQPAQQQQ 315
+ +G P TP + P+ P P+ + PS P+ P K P
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP 1087
Query: 316 PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP---AHPPP 372
P+ + +P P A SPK A PP P PP P A PPP
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPK--GGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145
Query: 373 DRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHR--PPPPPPSSYMT 430
P AA PP P P PP P PP P P P + T
Sbjct: 1146 KGAPTTPAAT----PPSPKGGLATP----PPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197
Query: 431 GMSTTSSYMSGEGYQSLQSMMKTEG-----PSYGALPPAYGPPAHLPYHPHVYPPNPPPP 485
+T S G S + T P G P+ P P P PP+P
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAATPPSPKGG 1254
Query: 486 PVPPPPASFP-PPAIPPPT--PGYPPPPPTYNPN---FPPPPPRLPPTHAVPPHPPPGLG 539
P PPP P PPA PP+ G PP PN PP P+ P + PP G
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS----PPKGAP 1310
Query: 540 LPPASYPP-PAVPPGGQPPVPPPIPPPGMPP 569
PPA+ PP P PG PP P PP PP
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Score = 99.0 bits (245), Expect = 1e-20
Identities = 100/338 (29%), Positives = 122/338 (36%), Gaps = 44/338 (13%)
Query: 269 TPHQLQQPPSLQP-TPQVPQVQQSQPSQSSEPSQPQQKDPQ-QPAQQQQPAQQPKKPSPQ 326
+P PP++ P +P+ P +S P P+ PA P P P+
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 327 PSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHP---PLPPAHPPPDRKPPLAAALG 383
SP+ + AA PP PK T P P+PPA PP K LA
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPA-TPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 384 EAEPPGPVDATDLPK--VQIPPP--AHPAPVHQPP-PLPHRPPPPPPSSYMTGMSTTSSY 438
+ P P PK + PPP A P PP P PPP + T +T S
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 439 MSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPA-----S 493
G + T P PA PP+ P P P PP+ +
Sbjct: 1183 KGG---------LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 494 FPPPAIPPPTPGYPPPPPTYNPNFPPP------PPRLPPT----HAVPPH---PPPGLGL 540
P P P TP PP P P PPP P PP+ A PPH P P +
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT 1293
Query: 541 PPASYPPPAV-PPGGQPPVPPPIPP-----PGMPPVGG 572
PP+ PA PP G P P PP PG PP G
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Score = 95.1 bits (235), Expect = 2e-19
Identities = 101/326 (30%), Positives = 115/326 (35%), Gaps = 43/326 (13%)
Query: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRA 336
PSL+ P P + PS P+ P K P P+ + +P A
Sbjct: 1074 PSLKGAPTPPAA--TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Query: 337 VVVSPKEENKAAEPPPPKIPKIETTHPPLPP---AHPPPDRKPPLAAAL-----GEAEPP 388
SPK A PPP P PP P A PPP P AA G P
Sbjct: 1132 TPPSPK--GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
Query: 389 GPVDATDLPKVQIPPP----AHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
P A P P P A P+P P P PP P T +
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 445 QSLQSMMKTEGPSYGALPPAYGPPA---HLPYHPHVYPPNP----PPPPV------PPPP 491
S + T P PPA PP+ L PH PNP PP P PP
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 492 ASFPPPAIPPPTPGYP-PPPPTYNPNFP---PPPPRLPPTHAVPPHPPPGLGLP--PASY 545
A PP A PP G P PPP P P PP P+ PT +P P G P P+S
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT--LPATTPSSKGGPTTPSSK 1366
Query: 546 ---PPPAVPPG--GQPPVPPPIPPPG 566
PPA P G P + PP P G
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRG 1392
Score = 95.1 bits (235), Expect = 2e-19
Identities = 89/306 (29%), Positives = 107/306 (34%), Gaps = 26/306 (8%)
Query: 269 TPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPS 328
TP P + TP P+ + P P+ P P P + +P +
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
Query: 329 SPRQVKRAVVVSPK--EENKAAEPPPPKIPKIETTHP---PLPPAHPPPDRKPPLAAALG 383
P SPK AA PP PK + T P P PA PP K LA
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPK-GGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 384 EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEG 443
+ P P PK PA P P P P P PPS + G T +
Sbjct: 1238 KGAPTTPAATPPSPK---GGPATPPPKGAPTP----PAATPPS--LKGGLATPPHKGAPN 1288
Query: 444 YQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPP-----PA 498
+ GP+ A PPA P P P PPP P PPA PP P
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 499 IPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP-PGGQPP 557
+P TP P T + P PP P+H P PP+ PA+P P G P
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP-----AMTPPSPKRGPAIPSPKGDPT 1403
Query: 558 VPPPIP 563
P IP
Sbjct: 1404 SPAVIP 1409
Score = 92.0 bits (227), Expect = 1e-18
Identities = 105/358 (29%), Positives = 124/358 (34%), Gaps = 59/358 (16%)
Query: 260 QGKQQMPHHTPHQLQQPPSLQPTPQV-----PQVQQSQPSQSSEPSQPQ----QKDPQQP 310
QG + P T P PTP P+ P ++ PS ++ P P
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENK----AAEPPPPKIPKIETTHP--- 363
A +Q PA SP+ + + + SP + AA PP PK T P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA-TPSPKWA 962
Query: 364 PLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPP 423
P PPA PP K A + P P PK PA P+P P P PP P
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK---GGPATPSPKGAPTPPAVTPPSP 1019
Query: 424 PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483
S T +S + PS P A P P P P+P
Sbjct: 1020 KGSPAATPFPKGAS-----------TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 484 PPPVPPP--PASFPPPAIPP--------PTPGYPPPPPTYNPNFP-----PPPPRLPPT- 527
P P A PP A PP P+P P PP P P PP + PT
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 528 -HAVPPHPPPGLGLPP---ASYPPPAVPPG--GQPPVPPPIPPPGMP------PVGGL 573
A PP P GL PP A P A PP G PPP P P P GGL
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Score = 89.0 bits (219), Expect = 1e-17
Identities = 98/350 (28%), Positives = 120/350 (34%), Gaps = 61/350 (17%)
Query: 272 QLQQPPSLQPT--PQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
Q ++PP+ + + P P S P E S + + PA SP P S
Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH---SPTPPS 860
Query: 330 PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP---PAHPPPDRKPPLAAALGEAE 386
P+ V+P K PP + P + P P PA P P + P L+ +
Sbjct: 861 PKGAPTPSAVTPLSP-KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT---SS 916
Query: 387 PPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQS 446
P AT PK PA P+P P P P PP P T + S
Sbjct: 917 SPKKARATPAPK---GIPASPSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 447 LQSMMKTEGPSYGALPPAYGPPAH-----------LPYHPHVYPPNPP------------ 483
+ T P PPA PP+ P P V PP+P
Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA 1032
Query: 484 --PPPVPPP-----PASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHP-- 534
PP PP PA+ P P P TP P P P P P A PP P
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Query: 535 ------PPGLGLPPASYPPP-----AVPPGGQPPVPPPIPPPGMPPVGGL 573
P G +PPA+ PP A PP P P PP P GGL
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS--PKGGL 1140
Score = 77.0 bits (188), Expect = 4e-14
Identities = 80/308 (25%), Positives = 114/308 (37%), Gaps = 42/308 (13%)
Query: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKP-S 324
P H PPS + P +P + S + P P +K P P ++ A K +
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPVTREGAATPSKGDLT 1434
Query: 325 PQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGE 384
P +P +K+A S + A P K P LP PP ++PP +
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPAT--PSSK------GDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 385 AEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY 444
+ P AT P + P PA + P + P PSS ++ T++ +S
Sbjct: 1487 SSSPKKAPATPAP---MGAPTLPAVIPSSP----KEVPATPSSRRDPIAPTATLLS---- 1535
Query: 445 QSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPAS---FPPPAIPP 501
+ T P +PPA P+ P P P P P P+S PPA+ P
Sbjct: 1536 ---KKTPATLAPKEALIPPAMTVPS-----PKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 502 PTPGYPPPPP--TYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVP 559
T P P P P P+ PT PP + PP+ PA P P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPT-------PPAV-TPPSPEKGPATPAPKGTPTS 1639
Query: 560 PPIPPPGM 567
PP+ P +
Sbjct: 1640 PPVTPSSL 1647
Score = 75.5 bits (184), Expect = 1e-13
Identities = 88/334 (26%), Positives = 113/334 (33%), Gaps = 47/334 (14%)
Query: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEE- 344
P++ +S PS S P+ + A P SP+ + S K
Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787
Query: 345 NKAAEPPPPKIPKI--ETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIP 402
A+ P P + +T PP PD P+ + P PV+A+ LP+ +
Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT--PIGNL---SSPVSPVEASFLPENSLS 842
Query: 403 ---PPAHPAPVHQP-PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY 458
PA H P PP P P P + ++ T + EGP+
Sbjct: 843 FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902
Query: 459 GA--LPPAYGPPAHLPYH------PHVYPPNPPPPPVPPPPASFPP-----PAIP----- 500
A PA + P P P +P P P PPA+ PP PA P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 501 PPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHP--------PPGLGLPPASYPP----- 547
P P PP P P P P P A PP P P G PPA PP
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
Query: 548 PAVPP----GGQPPVPPPIPPPGMPPVGGLGRAA 577
PA P PP P P G P L + A
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Score = 75.1 bits (183), Expect = 2e-13
Identities = 82/313 (26%), Positives = 109/313 (34%), Gaps = 64/313 (20%)
Query: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQ--PAQQQQPAQQPKKPSPQPS--SPR 331
PPS + TP +P S + PS + P P+ + PA P P P+ SP+
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
Query: 332 QVKRAVVVSPKEENKAAEPP---------------PPKIPKIE------TTHPPLPPAHP 370
+ V P KA P PP + + T+ P PA P
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 371 PPDRKPPLAAALGEA--EPPGP--VDATDLPKVQIPPPAHPAPVHQPP-----PLPHRPP 421
P L A + EPP P V + PK PA PAP+ P P +
Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK---KAPATPAPMGAPTLPAVIPSSPKEV 1516
Query: 422 PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAH-----LPYHPH 476
P PSS ++ T++ +S + T P +PPA P+ +P P
Sbjct: 1517 PATPSSRRDPIAPTATLLS-------KKTPATLAPKEALIPPAMTVPSPKKTPAIPT-PK 1568
Query: 477 VYPPNPPPPPVPPPPASFP--------------PPAIPPPTPGYPPPPPTYNPNFPPPPP 522
P P PPA P PPA+ P+P P PP P P P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 523 RLPPTHAVPPHPP 535
P P PP
Sbjct: 1629 ATPAPKGTPTSPP 1641
Score = 56.2 bits (134), Expect = 8e-08
Identities = 74/314 (23%), Positives = 104/314 (33%), Gaps = 36/314 (11%)
Query: 277 PSLQPTPQVPQVQQSQPSQSS-EPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKR 335
PS + TP +P +++ + SS E S P P P + P+ SP++
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 336 AVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAH--PPPDRKPPLAAALGEAEP------ 387
V+P K P PK T PP+ P+ P + +G P
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTP---TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 388 PGPVDATDLPKVQIPPPAHPAPVHQPP----PLPHR-----PPPPPPSSYMTGMSTTSSY 438
P T L +V + P P+ P P + PP P S G S
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
Query: 439 MSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA 498
++ +Q A +H P P P + P+ P
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDA--------SHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 499 IPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPV 558
+ P PP P P P P LPP P PGL L S P + P + +
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP-SSPGLVLESPSKP---LAPADEDEL 1840
Query: 559 PPPIPPPGMPPVGG 572
P IPP P+ G
Sbjct: 1841 LPLIPP---EPISG 1851
Score = 54.7 bits (130), Expect = 2e-07
Identities = 58/218 (26%), Positives = 73/218 (33%), Gaps = 9/218 (4%)
Query: 355 IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP--VHQ 412
+P + T P A P + PLA + E P V + LP PP H
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 413 PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGP-SYGALPPAYGPPAHL 471
P P + +G S T+S +L + + P P PP
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKG-----TLTYLADSPSPLGVSVSPQTKRPPTKK 812
Query: 472 PYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVP 531
P PV P ASF P P T++P PP P P AV
Sbjct: 813 GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT-PPSPKGAPTPSAVT 871
Query: 532 PHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
P P G+ LPP P P+V P P P P P
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Score = 38.1 bits (87), Expect = 0.022
Identities = 50/213 (23%), Positives = 67/213 (31%), Gaps = 33/213 (15%)
Query: 359 ETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPH 418
E P A P + AALG+ PGP +PPP PAP P +
Sbjct: 15 ELPQPQAETAVLPMSSALSVTAALGQ---PGPT---------LPPPCSPAPQQCPLSAAN 62
Query: 419 RPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVY 478
+ P P S + + +L E P++ LP GP P P
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF--LPNLIGP----PISPAAL 116
Query: 479 PPNPP--PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA------- 529
P P + P+S P A+ P + PN PP + +
Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Query: 530 ---VPPHPPPGLGLPPASYPPPAVPPGGQPPVP 559
P P L P+ P P G P P
Sbjct: 177 APIAPSEPKTNLNKVPSEVVP---NPKGTPSPP 206
Score = 32.0 bits (71), Expect = 1.6
Identities = 68/305 (22%), Positives = 97/305 (31%), Gaps = 26/305 (8%)
Query: 269 TPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPS 328
T +L QP + T +P + + P P PA QQ P + SP PS
Sbjct: 12 TEQELPQPQA--ETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 329 SPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPL--PPAHPPPDRKPPLAAALGEAE 386
+ V + + P P+ T P L PP P AAL A
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP---------AALALAS 120
Query: 387 P-------PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYM 439
P P + L V + P + PP L PP + + ++ ++
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
Query: 440 SGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAI 499
E +L + P+ P + +PYH V P V P + P +
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYH-CVTPMASIQSGVASLPQTTPTTTL 239
Query: 500 PPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVP 559
+P + P P L + P PP L L S P V Q
Sbjct: 240 AIASPQVKDTTISSVLISPQNPGSL--SLKGPVSPPAALSLSTQSLP---VVTSSQKTAG 294
Query: 560 PPIPP 564
P PP
Sbjct: 295 PNTPP 299
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 103 bits (258), Expect = 3e-22
Identities = 96/323 (29%), Positives = 125/323 (38%), Gaps = 68/323 (21%)
Query: 276 PPSLQPTPQVPQVQQSQPS-QSSEPSQPQQKDPQQPAQQQQPAQQPKK-PSPQPSSPRQV 333
P + P P + QS+P +S PS+ + P P P P PS +
Sbjct: 349 PANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPS----L 404
Query: 334 KRAVVVSPKEENKAAEPPP----PKIPKIETTHPPLPPAHPPPDR---KPPLAAAL---- 382
P + N PPP P P + HPP PP D+ P+ + +
Sbjct: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
Query: 383 -GEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP------------HRPPPPPPSSYM 429
G+ P P P +PPP P P QPPP P PPPPPPSS M
Sbjct: 465 QGKGMMPPP------PMGMMPPPP-PPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
Query: 430 TGMS--------TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN 481
+ TT++ +G G + + P G P +P P V PP
Sbjct: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
Query: 482 PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLP 541
PP P PP PPP PP + G PP PPPPP + P++ V G+G+
Sbjct: 578 PPGAPPPP-----PPP--PPGSAGMMYAPP------PPPPPPMDPSNFVTMM---GMGVA 621
Query: 542 PASYPPPAVPPGGQPPVPPPIPP 564
+PP G PP PPP PP
Sbjct: 622 -------GMPPFGMPPAPPPPPP 637
Score = 83.2 bits (204), Expect = 6e-16
Identities = 89/322 (27%), Positives = 109/322 (33%), Gaps = 78/322 (24%)
Query: 307 PQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP 366
P PA P +P+P++P A PPPP + + PP
Sbjct: 326 PASVGSTSGPATTPLASAPRPAAP----------------ANNPPPPSLMSTTQSRPPWM 369
Query: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLP-----------KVQIPPPAHPAPVHQPPP 415
+ P R G P G + P +Q P P P QPPP
Sbjct: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP 429
Query: 416 LPHRPPPPPPSSYMTGMSTTSSYMS----GEG-YQSLQSMMKTEGPSYGALPPAYGPPAH 470
P P PP + G Y+ G G Y+ Q P G +PP PP+
Sbjct: 430 PPMNQGPHPPGHH--GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487
Query: 471 LPYHPHVYP----------PNPPPPPVPPPPASFPPP---------------AIPP---- 501
P P P P PPPPP +S P P +IPP
Sbjct: 488 QPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQ 547
Query: 502 -----PTPGYPPPP--PTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGG 554
+PG P PT P P P LPP A PP PPP G Y PP
Sbjct: 548 QAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG-APPPPPPPPPGSAGMMYAPP------ 600
Query: 555 QPPVPPPIPPPGMPPVGGLGRA 576
PP PPP+ P + G+G A
Sbjct: 601 -PPPPPPMDPSNFVTMMGMGVA 621
Score = 78.2 bits (191), Expect = 2e-14
Identities = 77/220 (35%), Positives = 85/220 (38%), Gaps = 55/220 (25%)
Query: 378 LAAALGEAEPPGPVDATD----LPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMS 433
L A LGEA P V +T P P PA PA PPPPS T S
Sbjct: 316 LMAELGEAPVPASVGSTSGPATTPLASAPRPAAPAN-----------NPPPPSLMSTTQS 364
Query: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGP---PAHLPY-------HPHVYPPNPP 483
SG M GP P GP P LP HP + PN P
Sbjct: 365 RPPWMNSGPSESRPYHGMHGGGPG----GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 484 PPP-VPPPPASFPPPAIPPPTPGY--PPPPPTYNPNFPPP-------------PPRLPPT 527
PPP + PPP PP P PG+ PPP Y + P PP PP
Sbjct: 421 PPPWMQPPP---PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP--PPM 475
Query: 528 HAVPPHPPPGLGLPPASYPPPA--VPPGGQPPVPPPIPPP 565
+PP PPP G PP PPP+ +PP Q PP PPP
Sbjct: 476 GMMPPPPPPPSGQPP---PPPSGPLPPWQQQQQQPPPPPP 512
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 66/232 (28%)
Query: 260 QGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQ 319
QGK MP P + P P P Q P S P P Q+ QQP P+
Sbjct: 465 QGKGMMP-------PPPMGMMPPPPPPPSGQPPPPPSG-PLPPWQQQQQQPPPPPPPSSS 516
Query: 320 PKKPSPQPSSPRQVKRAV-----VVSPKEENKAAEPPPPKIPKIE--TTHPPLPPAHPPP 372
+P P + P ++ +AA P P+++ T PLPP PP
Sbjct: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP 576
Query: 373 DRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGM 432
PP G PP P PPP ++ PPP P PPP PS+++T M
Sbjct: 577 --LPP-----GAPPPPPP-----------PPPGSAGMMYAPPPPP--PPPMDPSNFVTMM 616
Query: 433 STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP 484
G +PP PPA PP PPP
Sbjct: 617 ----------------------GMGVAGMPPFGMPPA---------PPPPPP 637
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 103 bits (258), Expect = 3e-22
Identities = 63/231 (27%), Positives = 117/231 (50%), Gaps = 22/231 (9%)
Query: 43 PATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFL 102
PA EAR ARFI + G +LG+ +AT +H+F+ + + Y+ ++L
Sbjct: 20 PAPEARVHFRVARFIMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYL 79
Query: 103 AGKVEETPKKCKDIIKTARSLLN--------DVQFGQFGDDPKEEVMVLERILLQTIKFD 154
AGKVEE + +DII + N D +F + ++ ++ E ++L+ ++F
Sbjct: 80 AGKVEEQHLRTRDIINVSNRYFNPSGEPLELDSRFWEL----RDSIVQCELLMLRVLRFQ 135
Query: 155 LQVEHPYQFLLKYAKQLKGDKNKIQ----KLVQMAWTFVNDSLCTTLSLQWEPEIIAVAV 210
+ +HP+++LL Y L+ N+ + AW + DS L L+++ + IAVAV
Sbjct: 136 VSFQHPHKYLLHYLVSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAV 195
Query: 211 MYLAGRLCKFEI--QEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYS 259
+YLA ++ E+ + KP WW+ F D+ ++++I ++ +Y+
Sbjct: 196 LYLALQVYGVEVPAEVEAEKP----WWQVFNDDLTKPIIDNIVSDLIQIYT 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,405,264
Number of Sequences: 37866
Number of extensions: 3665337
Number of successful extensions: 143724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1594
Number of HSP's successfully gapped in prelim test: 2052
Number of HSP's that attempted gapping in prelim test: 22136
Number of HSP's gapped (non-prelim): 40490
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.