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Search of human proteins with 149999352
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149999352 forkhead box P2 isoform II [Homo sapiens]
(740 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 1466 0.0
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 1396 0.0
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 1241 0.0
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 829 0.0
gi|60498989 forkhead box P4 isoform 1 [Homo sapiens] 706 0.0
gi|29789367 forkhead box P4 isoform 2 [Homo sapiens] 696 0.0
gi|60498992 forkhead box P4 isoform 3 [Homo sapiens] 683 0.0
gi|167466190 forkhead box P3 isoform b [Homo sapiens] 221 2e-57
gi|31982943 forkhead box P3 isoform a [Homo sapiens] 221 2e-57
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 123 7e-28
gi|110347429 mediator complex subunit 12 [Homo sapiens] 121 3e-27
gi|221139761 zinc finger protein 853 [Homo sapiens] 120 5e-27
gi|33286444 mastermind-like 2 [Homo sapiens] 118 2e-26
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 111 2e-24
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 111 2e-24
gi|93141033 PAX interacting protein 1 [Homo sapiens] 94 3e-19
gi|226246533 TOX high mobility group box family member 3 isoform... 94 5e-19
gi|226054295 TOX high mobility group box family member 3 isoform... 94 5e-19
gi|50301236 forkhead box J1 [Homo sapiens] 91 3e-18
gi|4507379 TATA box binding protein [Homo sapiens] 88 3e-17
gi|50345831 forkhead box J3 [Homo sapiens] 88 3e-17
gi|24497506 forkhead box A3 [Homo sapiens] 87 4e-17
gi|31563338 forkhead box K2 [Homo sapiens] 83 8e-16
gi|4885237 forkhead box C2 [Homo sapiens] 82 2e-15
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 82 2e-15
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 82 2e-15
gi|148746195 trichohyalin [Homo sapiens] 82 2e-15
gi|40549454 T-cell leukemia virus enhancer factor [Homo sapiens] 81 4e-15
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] 80 7e-15
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] 80 7e-15
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 1466 bits (3795), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA
Sbjct: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMT 120
ARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMT
Sbjct: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMT 120
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ
Sbjct: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL
Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Query: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 300
VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG
Sbjct: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 300
Query: 301 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 360
VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE
Sbjct: 301 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 360
Query: 361 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 420
TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL
Sbjct: 361 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 420
Query: 421 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 480
SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT
Sbjct: 421 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 480
Query: 481 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 540
PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ
Sbjct: 481 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 540
Query: 541 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 600
AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV
Sbjct: 541 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 600
Query: 601 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 660
DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS
Sbjct: 601 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 660
Query: 661 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 720
GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH
Sbjct: 661 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 720
Query: 721 SPELEDDREIEEEPLSEDLE 740
SPELEDDREIEEEPLSEDLE
Sbjct: 721 SPELEDDREIEEEPLSEDLE 740
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 1396 bits (3614), Expect = 0.0
Identities = 715/740 (96%), Positives = 715/740 (96%), Gaps = 25/740 (3%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA
Sbjct: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQA 60
Query: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMT 120
ARQLLLQQQTSGLKSPKSSDKQRPLQ VPVSVAMMT
Sbjct: 61 ARQLLLQQQTSGLKSPKSSDKQRPLQ-------------------------VPVSVAMMT 95
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ
Sbjct: 96 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
Query: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL
Sbjct: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Query: 241 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 300
VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG
Sbjct: 216 VFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTG 275
Query: 301 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 360
VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE
Sbjct: 276 VHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEE 335
Query: 361 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 420
TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL
Sbjct: 336 TGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQL 395
Query: 421 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 480
SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT
Sbjct: 396 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 455
Query: 481 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 540
PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ
Sbjct: 456 PITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQ 515
Query: 541 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 600
AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV
Sbjct: 516 AIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTV 575
Query: 601 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 660
DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS
Sbjct: 576 DEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASS 635
Query: 661 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 720
GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH
Sbjct: 636 GLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANH 695
Query: 721 SPELEDDREIEEEPLSEDLE 740
SPELEDDREIEEEPLSEDLE
Sbjct: 696 SPELEDDREIEEEPLSEDLE 715
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 1241 bits (3210), Expect = 0.0
Identities = 623/623 (100%), Positives = 623/623 (100%)
Query: 118 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 177
MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ
Sbjct: 1 MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60
Query: 178 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Query: 238 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 297
QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE
Sbjct: 121 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 180
Query: 298 VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS 357
VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS
Sbjct: 181 VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSS 240
Query: 358 HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE 417
HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE
Sbjct: 241 HEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLE 300
Query: 418 IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA 477
IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA
Sbjct: 301 IQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA 360
Query: 478 PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL 537
PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL
Sbjct: 361 PVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL 420
Query: 538 IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV 597
IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV
Sbjct: 421 IRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAV 480
Query: 598 WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN 657
WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN
Sbjct: 481 WTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINN 540
Query: 658 ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT 717
ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT
Sbjct: 541 ASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTT 600
Query: 718 ANHSPELEDDREIEEEPLSEDLE 740
ANHSPELEDDREIEEEPLSEDLE
Sbjct: 601 ANHSPELEDDREIEEEPLSEDLE 623
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 41/133 (30%)
Query: 47 VELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP 106
++LL QQQQ Q +Q QQQ + + +Q+ Q+
Sbjct: 56 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------------- 96
Query: 107 HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK 166
P +Q QQ QQQ L+ QQL + QQQ +LQ QQL
Sbjct: 97 ----------QQQHPGKQAKEQQQQQQQQQQLAAQQL--VFQQQ---LLQMQQL------ 135
Query: 167 QQEQLHLQLLQQQ 179
Q+Q HL LQ+Q
Sbjct: 136 -QQQQHLLSLQRQ 147
>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
Length = 677
Score = 829 bits (2141), Expect = 0.0
Identities = 453/751 (60%), Positives = 541/751 (72%), Gaps = 85/751 (11%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS-RDGRSSGDTSS-EVSTVELLHLQQQQ-- 56
MMQES TET SN S QNG + L+ G R+GRS+G+T + ++ +L H QQQQ
Sbjct: 1 MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQ 60
Query: 57 ALQAARQLLLQQQ----TSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAV 112
ALQ ARQLLLQQQ SGLKSPK +DKQ LQ V
Sbjct: 61 ALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQ-------------------------V 95
Query: 113 PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLH 172
PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQ LL
Sbjct: 96 PVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLL------------------------- 130
Query: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
QQQQ QQQQ Q+ ++QQ+Q Q Q QQQH GKQ KEQQQ
Sbjct: 131 ------------QQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQ----- 173
Query: 233 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ 292
+A QQL FQQQLLQMQQLQQQ HLLSLQRQGL++I PGQ ALP+Q L Q G+ P E+Q
Sbjct: 174 --VATQQLAFQQQLLQMQQLQQQ-HLLSLQRQGLLTIQPGQPALPLQPLAQ-GMIPTELQ 229
Query: 293 QLWKEVTGVHSMEDN-GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSA 351
QLWKEVT H+ E+ G H LDLTT SS+ S TS P H+ NGQ SV +
Sbjct: 230 QLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNP---HASTNGQLSVHTP 286
Query: 352 RRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQ 411
+R+S SHEE SH LYGHGVCKWPGCE++CEDF FLKHLN+EHALDDRSTAQCRVQMQ
Sbjct: 287 KRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQ 346
Query: 412 VVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQT 471
VVQQLE+QL+K++ERLQAMMTHLH++ +EPK +P+PLNLVSSVT+SK+ E SPQSLP T
Sbjct: 347 VVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHT 406
Query: 472 PTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSS-EIAPNYEFYKNADVRP 530
PTTPTAP+TP+TQGPSVIT S+ VG IRRR+SDKYN+P+SS +IA N EFYKNA+VRP
Sbjct: 407 PTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRP 466
Query: 531 PFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRV 590
PFTYA+LIRQAI+ES ++QLTLNEIY+WFTR FAYFRRNAATWKNAVRHNLSLHKCFVRV
Sbjct: 467 PFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRV 526
Query: 591 ENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLS 650
ENVKGAVWTVDEVE+QKRR QKI+G+P+L+KN+ +S Y LNA+LQA++AE+S+PL +
Sbjct: 527 ENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYT 586
Query: 651 NPGLINNASSGLLQAVHEDLNGSLDHIDSN-GNSSPGCSPQPHIHSIHVKEEPVIAEDED 709
+ N L A+ E+LNG+++H +SN +SSPG SP +H +HVKEEP+ E+ +
Sbjct: 587 TASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAE 646
Query: 710 CPMSLVTTANHSPELEDDREIEEEPLSEDLE 740
P+SLVTTANHSP+ + DR+ E+EP++ED+E
Sbjct: 647 GPLSLVTTANHSPDFDHDRDYEDEPVNEDME 677
>gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]
Length = 680
Score = 706 bits (1821), Expect = 0.0
Identities = 407/760 (53%), Positives = 501/760 (65%), Gaps = 102/760 (13%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHN 108
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAV-------------------- 99
Query: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
VPVSVAMM+PQ++TPQQMQQIL SP QLQALLQQQQA+ML
Sbjct: 100 --QVPVSVAMMSPQMLTPQQMQQIL-----SPPQLQALLQQQQALML------------- 139
Query: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
QQ Q+ ++QQ+Q Q QQQ GK
Sbjct: 140 -------------------QQLQEYYKKQQEQLHLQLLTQQQ-------AGK-------- 165
Query: 229 QQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
Q ++ L +QL FQQQLLQMQQL QQQHLL+LQRQGL+S+ P QA+ P+Q+LPQA + P
Sbjct: 166 PQPKEALGNKQLAFQQQLLQMQQL-QQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCP 224
Query: 289 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 348
++ QLWK ++ +K GLDLT +++T+ + K SPP++HH++ NGQ +V
Sbjct: 225 TDLPQLWKGEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTV 284
Query: 349 LSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRV 408
L++RRDSSSHEET SH LYGHG CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRV
Sbjct: 285 LTSRRDSSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRV 344
Query: 409 QMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLV------SSVTMSKNMLE 462
QMQVVQQLEIQL+KE ERLQAMM HLHMRPSEPKP +PLN V S VT+S +
Sbjct: 345 QMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVS--AAD 402
Query: 463 TSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEF 522
+ P L PT+ APVTP+ P + AS+ G RRR SDK+ P+SSE+A N+EF
Sbjct: 403 SFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEF 460
Query: 523 YKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLS 582
YKNADVRPPFTYA+LIRQAI+E+ DRQLTLNEIY+WFTR FAYFRRN ATWKNAVRHNLS
Sbjct: 461 YKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLS 520
Query: 583 LHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALA 642
LHKCFVRVENVKGAVWTVDE EYQKRR K+TGSPTLVKN+ + L YG ALNAS QAALA
Sbjct: 521 LHKCFVRVENVKGAVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYG-ALNASYQAALA 579
Query: 643 ESSLPLLSNPGLIN-NASSGLLQAVHEDLNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKE 700
ESS PLL++PG++N ++S LL H+D+ ++ + SNG+SS P SP + H + VKE
Sbjct: 580 ESSFPLLNSPGMLNPGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKE 639
Query: 701 EPVIAEDEDCPMSLVTTANHSPE-LEDDREIEEEPLSEDL 739
EP AE++ P + N S +DR++EEE E+L
Sbjct: 640 EPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELPGEEL 679
>gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]
Length = 667
Score = 696 bits (1795), Expect = 0.0
Identities = 400/754 (53%), Positives = 497/754 (65%), Gaps = 103/754 (13%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHN 108
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAV-------------------- 99
Query: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
VPVSVAMM+PQ++TPQQMQQIL SP QLQALLQQQQA+ML
Sbjct: 100 --QVPVSVAMMSPQMLTPQQMQQIL-----SPPQLQALLQQQQALML------------- 139
Query: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
QQ Q+ ++QQ+Q Q QQQ GK
Sbjct: 140 -------------------QQLQEYYKKQQEQLHLQLLTQQQ-------AGK-------- 165
Query: 229 QQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
Q ++ L +QL FQQQLLQMQQL QQQHLL+LQRQGL+S+ P QA+ P+Q+LPQA + P
Sbjct: 166 PQPKEALGNKQLAFQQQLLQMQQL-QQQHLLNLQRQGLVSLQPNQASGPLQTLPQA-VCP 223
Query: 289 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 348
++ QLWK ++ +K GLDLT +++T+ + K SPP++HH++ NGQ +V
Sbjct: 224 TDLPQLWKGEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTV 283
Query: 349 LSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRV 408
L++RRDSSSHEET SH LYGHG CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRV
Sbjct: 284 LTSRRDSSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRV 343
Query: 409 QMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSL 468
QMQVVQQLEIQL+KE ERLQAMM HLHMRPSEPKP +P+ + ++ ++ P L
Sbjct: 344 QMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPVTVSAA--------DSFPDGL 395
Query: 469 PQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADV 528
PT+ APVTP+ P + AS+ G RRR SDK+ P+SSE+A N+EFYKNADV
Sbjct: 396 VHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADV 453
Query: 529 RPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFV 588
RPPFTYA+LIRQAI+E+ DRQLTLNEIY+WFTR FAYFRRN ATWKNAVRHNLSLHKCFV
Sbjct: 454 RPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFV 513
Query: 589 RVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPL 648
RVENVKGAVWTVDE EYQKRR K+TGSPTLVKN+ + L YG ALNAS QAALAESS PL
Sbjct: 514 RVENVKGAVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYG-ALNASYQAALAESSFPL 572
Query: 649 LSNPGLIN-NASSGLLQAVHEDLNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKEEPVIAE 706
L++PG++N ++S LL H+D+ ++ + SNG+SS P SP + H + VKEEP AE
Sbjct: 573 LNSPGMLNPGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAE 632
Query: 707 DEDCPMSLVTTANHSPE-LEDDREIEEEPLSEDL 739
++ P + N S +DR++EEE E+L
Sbjct: 633 EDRQPGPPLGAPNPSASGPPEDRDLEEELPGEEL 666
>gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]
Length = 678
Score = 683 bits (1763), Expect = 0.0
Identities = 396/760 (52%), Positives = 491/760 (64%), Gaps = 104/760 (13%)
Query: 1 MMQESATETISNSSMNQNGMSTLSSQLDAGS------------RDGRSSGDTSSEVSTVE 48
MM ESA+ETI ++ QNG+ +LS Q D S R+ + D++ E+S E
Sbjct: 1 MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTGREVTTGADSNGEMSPAE 60
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHN 108
LLH QQQQALQ ARQ LLQQ SGL SP ++D ++ +
Sbjct: 61 LLHFQQQQALQVARQFLLQQ-ASGLSSPGNNDSKQSASAV-------------------- 99
Query: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
VPVSVAMM+PQ++T PQQ+Q +L Q
Sbjct: 100 --QVPVSVAMMSPQMLT--------------PQQMQQILSPPQ----------------- 126
Query: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
LQ L QQQQ QQ+ ++QQ+Q Q QQQ GK
Sbjct: 127 ----LQALLQQQQALMLQQEYYKKQQEQLHLQLLTQQQA-----------GKP------- 164
Query: 229 QQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
Q ++ L +QL FQQQLLQMQQLQQQ HLL+LQRQGL+S+ P QA+ P+Q+LPQA + P
Sbjct: 165 -QPKEALGNKQLAFQQQLLQMQQLQQQ-HLLNLQRQGLVSLQPNQASGPLQTLPQAAVCP 222
Query: 289 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 348
++ QLWK ++ +K GLDLT +++T+ + K SPP++HH++ NGQ +V
Sbjct: 223 TDLPQLWKGEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTV 282
Query: 349 LSARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRV 408
L++RRDSSSHEET SH LYGHG CKWPGCE++CED GQF+KHLN EHALDDRSTAQCRV
Sbjct: 283 LTSRRDSSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRV 342
Query: 409 QMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLV------SSVTMSKNMLE 462
QMQVVQQLEIQL+KE ERLQAMM HLHMRPSEPKP +PLN V S VT+S +
Sbjct: 343 QMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPGSSSFSKVTVS--AAD 400
Query: 463 TSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEF 522
+ P L PT+ APVTP+ P + AS+ G RRR SDK+ P+SSE+A N+EF
Sbjct: 401 SFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEF 458
Query: 523 YKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLS 582
YKNADVRPPFTYA+LIRQAI+E+ DRQLTLNEIY+WFTR FAYFRRN ATWKNAVRHNLS
Sbjct: 459 YKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLS 518
Query: 583 LHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALA 642
LHKCFVRVENVKGAVWTVDE EYQKRR K+TGSPTLVKN+ + L YG ALNAS QAALA
Sbjct: 519 LHKCFVRVENVKGAVWTVDEREYQKRRPPKMTGSPTLVKNMISGLSYG-ALNASYQAALA 577
Query: 643 ESSLPLLSNPGLIN-NASSGLLQAVHEDLNGSLDHIDSNGNSS-PGCSPQPHIHSIHVKE 700
ESS PLL++PG++N ++S LL H+D+ ++ + SNG+SS P SP + H + VKE
Sbjct: 578 ESSFPLLNSPGMLNPGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKE 637
Query: 701 EPVIAEDEDCPMSLVTTANHSPE-LEDDREIEEEPLSEDL 739
EP AE++ P + N S +DR++EEE E+L
Sbjct: 638 EPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELPGEEL 677
>gi|167466190 forkhead box P3 isoform b [Homo sapiens]
Length = 396
Score = 221 bits (563), Expect = 2e-57
Identities = 119/261 (45%), Positives = 163/261 (62%), Gaps = 18/261 (6%)
Query: 352 RRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQ 411
R+DS+ +S+ L +GVCKWPGCE + E+ FLKH +H LD++ AQC +Q +
Sbjct: 143 RKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQRE 202
Query: 412 VVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQT 471
+VQ LE QL E+E+L AM HL + + K S ++ SS S ++ Q
Sbjct: 203 MVQSLEQQLVLEKEKLSAMQAHLAGKMALTKAS----SVASSDKGSCCIVAAGSQG---- 254
Query: 472 PTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPP 531
PV P GP + ++ A+RR + E N +++K ++RPP
Sbjct: 255 ------PVVPAWSGPR----EAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPP 304
Query: 532 FTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVE 591
FTYATLIR AI+E+ ++Q TLNEIY WFTR FA+FR + ATWKNA+RHNLSLHKCFVRVE
Sbjct: 305 FTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVE 364
Query: 592 NVKGAVWTVDEVEYQKRRSQK 612
+ KGAVWTVDE+E++K+RSQ+
Sbjct: 365 SEKGAVWTVDELEFRKKRSQR 385
>gi|31982943 forkhead box P3 isoform a [Homo sapiens]
Length = 431
Score = 221 bits (563), Expect = 2e-57
Identities = 119/261 (45%), Positives = 163/261 (62%), Gaps = 18/261 (6%)
Query: 352 RRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQ 411
R+DS+ +S+ L +GVCKWPGCE + E+ FLKH +H LD++ AQC +Q +
Sbjct: 178 RKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQRE 237
Query: 412 VVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQT 471
+VQ LE QL E+E+L AM HL + + K S ++ SS S ++ Q
Sbjct: 238 MVQSLEQQLVLEKEKLSAMQAHLAGKMALTKAS----SVASSDKGSCCIVAAGSQG---- 289
Query: 472 PTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPP 531
PV P GP + ++ A+RR + E N +++K ++RPP
Sbjct: 290 ------PVVPAWSGPR----EAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPP 339
Query: 532 FTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVE 591
FTYATLIR AI+E+ ++Q TLNEIY WFTR FA+FR + ATWKNA+RHNLSLHKCFVRVE
Sbjct: 340 FTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVE 399
Query: 592 NVKGAVWTVDEVEYQKRRSQK 612
+ KGAVWTVDE+E++K+RSQ+
Sbjct: 400 SEKGAVWTVDELEFRKKRSQR 420
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 123 bits (308), Expect = 7e-28
Identities = 108/282 (38%), Positives = 137/282 (48%), Gaps = 50/282 (17%)
Query: 52 LQQQQALQAARQLLL--------QQQTSGLKS------------PKSSDKQRPLQELLPE 91
LQQQQ Q +Q LL QQQ G+++ P SS + +Q+L P+
Sbjct: 3734 LQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQ 3793
Query: 92 TKLCICGH---------------SSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQ 136
G + G PH + S + +PQ+ QQ Q ++ +
Sbjct: 3794 PPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLA--QQGQGLMGHR 3851
Query: 137 VLSPQQLQALLQ-QQQAVMLQQQQLQEFYKKQQEQLHL---------QLLQQQQQQQQQQ 186
+++ QQ Q Q QQQ M LQ+ Q L QL QQQQ QQQQQ
Sbjct: 3852 LVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ 3911
Query: 187 -QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQ 245
QQQQQQQ QQQQQ QQQQ QQQQQQQQ QQ +Q ++QQQQ QQQQQ QQ QQQ
Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
Query: 246 LLQMQQLQQQQHLLS--LQRQGLISIPPGQAALPVQSLPQAG 285
QM L Q + LLS Q+Q +++ PG A P+Q G
Sbjct: 3972 QQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
Score = 59.7 bits (143), Expect = 1e-08
Identities = 53/158 (33%), Positives = 79/158 (50%), Gaps = 16/158 (10%)
Query: 130 QQILQQQV-LSPQQLQALLQQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQQQ 184
QQ+LQ Q+ + +Q+ + ++A+ +Q+ + EF + E+L L QQ + Q+Q
Sbjct: 3518 QQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQ 3577
Query: 185 QQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
Q ++QQ++ + + +QQQQQQQQQQQQQQH A Q + +L
Sbjct: 3578 LDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG---- 3633
Query: 242 FQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQ 279
QLL LQ Q Q GL + PG ALP Q
Sbjct: 3634 ---QLLPGHGLQPPQGPPGGQAGGL-RLTPGGMALPGQ 3667
Score = 51.6 bits (122), Expect = 3e-06
Identities = 41/135 (30%), Positives = 51/135 (37%), Gaps = 1/135 (0%)
Query: 155 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 214
L + + +E KKQQ LQ QQQQQQQQQ Q + QQ
Sbjct: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
Query: 215 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL-QMQQLQQQQHLLSLQRQGLISIPPGQ 273
Q G Q Q QQ+L M + Q H+LS Q G + P Q
Sbjct: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQ 3371
Query: 274 AALPVQSLPQAGLSP 288
++ PV S G P
Sbjct: 3372 SSQPVLSQKPMGTMP 3386
Score = 51.2 bits (121), Expect = 3e-06
Identities = 69/305 (22%), Positives = 114/305 (37%), Gaps = 44/305 (14%)
Query: 207 QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ----QQQHLLSLQ 262
Q++Q Q QQQ K QQQQQQQQQ QQ + Q +Q QQ Q Q L +
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQ----QQHLLGQVAIQQQQQQGPGVQTNQALGPK 3772
Query: 263 RQGLISIPPGQAALPVQSL-------PQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLD 315
QGL+ P L VQ L PQ L PA++ L ++ G G +
Sbjct: 3773 PQGLMP-PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGA-----LGPQGPHRQ 3826
Query: 316 LTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTL--YGHGVC 373
+ S +S ++ + H +V Q ++ H++ G+ L +
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQ-----QQQQQQHQQQGSMAGLSHLQQSLM 3881
Query: 374 KWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQ-------------L 420
G + L+ L + L + Q + Q Q+ QQ ++Q
Sbjct: 3882 SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941
Query: 421 SKERERLQAMMTHLHMRPSEPK---PSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTA 477
+++++LQ L + + + + + + S+ +L Q Q P
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM 4001
Query: 478 PVTPI 482
P P+
Sbjct: 4002 PAKPL 4006
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/153 (27%), Positives = 75/153 (49%), Gaps = 29/153 (18%)
Query: 146 LLQQQQAVMLQQQQLQE---FYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ 202
L QQ + +Q + L+E ++K ++ L + ++ ++ + ++ + +QQ +
Sbjct: 3514 LFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSK 3573
Query: 203 QQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 262
Q+Q Q ++QQ++H A+ + +QQQQQQQ QQQ Q QQQH
Sbjct: 3574 IQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQ--------QQQ--Q-----QQQH----- 3613
Query: 263 RQGLISIPPGQA-----ALPVQSLPQAGLSPAE 290
++++ P Q+ LP Q LP GL P +
Sbjct: 3614 -SAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQ 3645
Score = 34.7 bits (78), Expect = 0.33
Identities = 24/68 (35%), Positives = 30/68 (44%)
Query: 168 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 227
Q + LQ + + Q + QQQQQ Q Q+Q QQ Q +Q Q PG Q Q
Sbjct: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
Query: 228 QQQQQQQL 235
Q QL
Sbjct: 4256 LLGCQPQL 4263
Score = 34.7 bits (78), Expect = 0.33
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 146 LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 205
L Q Q V+ + QL+ +QQ+QL Q L Q+Q QQ Q +Q Q+ Q Q
Sbjct: 4197 LRAQLQGVLAKNPQLRHLSPQQQQQL--QALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254
Query: 206 QQQQQQQQQQQHPGKQAKEQQQ 227
Q Q PG Q Q+
Sbjct: 4255 GLLGCQPQLGGFPGPQTGPLQE 4276
Score = 30.8 bits (68), Expect = 4.7
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 438 PSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNV 497
P E SP P L S + ++ L P+ P +P ++P +P+ + P + P P
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP-LSPPEESPPS 529
Query: 498 GAIRRRHSDKYNIPMSSEIAPNYE 521
A+ S P +S ++P +E
Sbjct: 530 PALETPLSPP---PEASPLSPPFE 550
Score = 30.4 bits (67), Expect = 6.2
Identities = 44/138 (31%), Positives = 58/138 (42%), Gaps = 23/138 (16%)
Query: 30 GSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELL 89
G G+ +SSE S+V HL Q ++ Q T L P+ +RP+Q
Sbjct: 4113 GGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQP--GSMTQNLLGPQQPMLERPMQNNT 4168
Query: 90 -PETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQIL----QQQVLSPQQ-- 142
P+ SG G P V +M Q+Q +L Q + LSPQQ
Sbjct: 4169 GPQPPKPGPVLQSGQGLP--------GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQ 4220
Query: 143 -LQALLQQQQAVMLQQQQ 159
LQALL Q+Q LQQ Q
Sbjct: 4221 QLQALLMQRQ---LQQSQ 4235
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 121 bits (303), Expect = 3e-27
Identities = 79/183 (43%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 73 LKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQI 132
L P +QRP + + G +S H T ++ MTP ++ Q +Q
Sbjct: 1984 LVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTP--MSAQGVQAG 2041
Query: 133 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 192
++ + P+Q Q QQQQ QQQQ Q+ ++QQ+Q H++ QQQQ +QQQQQQQQQ
Sbjct: 2042 VRSTAILPEQQQ---QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098
Query: 193 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQL 252
QQQQQQQQQQQQQQQQQ QQQQQQ + Q Q Q Q+Q Q QQ ++QL
Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQL 2158
Query: 253 QQQ 255
QQQ
Sbjct: 2159 QQQ 2161
Score = 110 bits (274), Expect = 6e-24
Identities = 75/151 (49%), Positives = 89/151 (58%), Gaps = 14/151 (9%)
Query: 125 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
T QQ I +S Q +QA ++ + QQQQ Q+ ++QQ+Q Q QQQQQ
Sbjct: 2020 TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA------- 237
+QQQQQQ +QQQQQQQQQQQQQQQQQQQQQQ +QQQ QQQQQQ AA
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ-------QQQQHQQQQQQQAAPPQPQPQ 2132
Query: 238 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS 268
Q FQ+Q LQ Q QQQ L Q Q +S
Sbjct: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Score = 92.0 bits (227), Expect = 2e-18
Identities = 56/105 (53%), Positives = 65/105 (61%), Gaps = 5/105 (4%)
Query: 189 QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 248
+QQQQQQQQQQQQQQQQQQQQQQQQQQ H +Q ++Q +QQQQQQ QQ QQQ Q
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQ 2107
Query: 249 MQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQ 293
QQ QQQQH Q+Q + PP + GL + QQ
Sbjct: 2108 QQQQQQQQHQQQQQQQ---AAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
Score = 87.4 bits (215), Expect = 4e-17
Identities = 53/108 (49%), Positives = 61/108 (56%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ QQ QQQ QQ QQQQ ++ QQQQ Q+ ++QQ+Q Q QQQQQ QQQQ
Sbjct: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQ 2120
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 234
QQQ Q Q Q Q Q Q+Q QQ QQQQQ + QQQ Q Q
Sbjct: 2121 QQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 30.4 bits (67), Expect = 6.2
Identities = 38/130 (29%), Positives = 41/130 (31%), Gaps = 22/130 (16%)
Query: 172 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA--------K 223
HLQ QQ Q+ Q QQ G QA
Sbjct: 1990 HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILP 2049
Query: 224 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 283
EQQQQQQQQQQ QQ QQQQ Q+Q I Q L Q Q
Sbjct: 2050 EQQQQQQQQQQ--------------QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQ 2095
Query: 284 AGLSPAEIQQ 293
+ QQ
Sbjct: 2096 QQQQQQQQQQ 2105
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 120 bits (301), Expect = 5e-27
Identities = 102/253 (40%), Positives = 128/253 (50%), Gaps = 34/253 (13%)
Query: 53 QQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAV 112
Q +Q Q L LQQQ D Q+ L +L E + H+
Sbjct: 105 QHEQLQQPQPHLELQQQPQ-------QDGQQQLSQLQQEKHQSV----------HHQELK 147
Query: 113 PVSVAMMTPQVITPQQMQ--QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQ 170
P M Q + PQQ+Q Q LQQQ +QLQ Q+Q V+ QQ+QLQ+ + Q++Q
Sbjct: 148 PELQLMHQQQQLQPQQVQEQQRLQQQ---QEQLQTQQAQEQQVLQQQEQLQQ--QVQEQQ 202
Query: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ 230
L Q +Q QQQQ QQQ+Q QQQQ QQQQ+Q QQQQQ QQQ +Q +QQQ Q
Sbjct: 203 LLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQL 262
Query: 231 QQQQLAAQQLVFQQQLL--QMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
QQQ L QQ QQQLL Q +QLQQQQ LQ+Q Q L Q L L P
Sbjct: 263 QQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQ--------QEQLQQQQLQPPPLEP 314
Query: 289 AEIQQLWKEVTGV 301
E +++ E+ V
Sbjct: 315 EEEEEVELELMPV 327
Score = 116 bits (290), Expect = 9e-26
Identities = 104/371 (28%), Positives = 159/371 (42%), Gaps = 34/371 (9%)
Query: 126 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLH-------LQLLQQ 178
P+ QQ +Q+ PQ L QQ Q QQQL + +++ + +H LQL+ Q
Sbjct: 98 PEPQQQPQHEQLQQPQPHLELQQQPQQD--GQQQLSQLQQEKHQSVHHQELKPELQLMHQ 155
Query: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238
QQQ Q QQ Q+QQ+ QQQQ+Q Q QQ Q+QQ QQQ+Q +Q +EQQ QQQQ+QL Q
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQ-QQVQEQQLLQQQQEQLQQQ 214
Query: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEV 298
QL+ QQ+ LQ QQ QQQQ L Q+Q L+ GQ + QA L ++Q ++
Sbjct: 215 QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQL 274
Query: 299 TGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSH 358
++ PP+ + ++ D S
Sbjct: 275 QQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPV--DLGSE 332
Query: 359 EETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEI 418
+E E Q L+ ++ Q ++Q + +QQLE
Sbjct: 333 QE---------------------LEQQRQELERQQELERQQEQRQLQLKLQ-EELQQLEQ 370
Query: 419 QLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAP 478
QL +++++L+ L + P E + + L + + LE P + P AP
Sbjct: 371 QLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAP 430
Query: 479 VTPITQGPSVI 489
+ P +
Sbjct: 431 AAVVVAPPGYV 441
Score = 108 bits (270), Expect = 2e-23
Identities = 103/283 (36%), Positives = 141/283 (49%), Gaps = 63/283 (22%)
Query: 47 VELLHLQQQ-QALQAARQLLLQQQTSGLKSPKSSDKQ-RPLQELLPETKLCICGHSSGDG 104
++L+H QQQ Q Q Q LQQQ L++ ++ ++Q QE L +
Sbjct: 150 LQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ------------- 196
Query: 105 HPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQ-QLQALLQQQQAVMLQQQQLQEF 163
+ Q + QQ +Q+ QQQ+L Q QLQ QQQ LQQQQ Q
Sbjct: 197 -------------QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQ-QLL 242
Query: 164 YKKQQEQLHLQLLQQQQQQQQQQ--QQQQ---------QQQQQQQQQQQQQ--QQQQQQQ 210
+QQ QL QLLQQQQ Q QQQ +QQQ QQQ+Q QQQQQQQ QQQQ+Q
Sbjct: 243 LLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQL 302
Query: 211 QQQQQQHPGKQAKE---------------QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQ 255
QQQQ Q P + +E +Q+ +QQ+Q+L QQ + +QQ + QL+ Q
Sbjct: 303 QQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQ 362
Query: 256 QHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEV 298
+ L L++Q + Q L Q + Q L+P E+ +EV
Sbjct: 363 EELQQLEQQ----LEQQQQQLEQQEV-QLELTPVELGAQQQEV 400
Score = 91.3 bits (225), Expect = 3e-18
Identities = 78/255 (30%), Positives = 131/255 (51%), Gaps = 29/255 (11%)
Query: 48 ELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQ--------ELLPETKLCICGH 99
++L Q+Q Q Q LLQQQ L+ + +Q LQ E L + + +
Sbjct: 186 QVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQ 245
Query: 100 SSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM----- 154
G + A + Q++ QQ Q LQQQ+L QQ Q QQQQ ++
Sbjct: 246 QQGQLQQQ---LLQQQQAQLQQQLLEQQQAQ--LQQQLLLQQQEQLQQQQQQQLLQQQQE 300
Query: 155 -LQQQQLQ--EFYKKQQEQLHLQL----LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207
LQQQQLQ +++E++ L+L L +Q+ +QQ+Q+ ++QQ+ ++QQ+Q+Q Q +
Sbjct: 301 QLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLK 360
Query: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ----QLQQQQHLLSLQR 263
Q++ QQ + +Q ++Q +QQ+ Q +L +L QQQ +Q++ Q + Q L+
Sbjct: 361 LQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420
Query: 264 QGLISIPPGQAALPV 278
G ++P AA+ V
Sbjct: 421 GGGAAVPGAPAAVVV 435
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/267 (18%), Positives = 99/267 (37%), Gaps = 24/267 (8%)
Query: 196 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ---QQLLQMQQL 252
+ Q++++ Q++ Q+ P ++ ++ + Q++L QQL Q QQ Q +QL
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQL 109
Query: 253 QQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHS--------- 303
QQ Q L LQ+Q P + L Q Q+L E+ +H
Sbjct: 110 QQPQPHLELQQQ-----PQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV 164
Query: 304 MEDNGIKHGGLDLTTNNS-SSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETG 362
E ++ L T + + + ++ Q L ++ E+
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQ 224
Query: 363 ASHTLYGHGVCKWPGCESICEDFGQFLKHL------NNEHALDDRSTAQCRVQMQVVQQL 416
+ + + GQ + L + L ++ AQ + Q+ + QQ
Sbjct: 225 QQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284
Query: 417 EIQLSKERERLQAMMTHLHMRPSEPKP 443
++Q ++++ LQ L + +P P
Sbjct: 285 QLQQQQQQQLLQQQQEQLQQQQLQPPP 311
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 20/95 (21%)
Query: 177 QQQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 227
+ Q++++ Q++ Q+ + ++ + Q++ Q QQ +QQ P QQQ
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEP------QQQ 103
Query: 228 QQQQQQQLAAQQLVFQQQ-----LLQMQQLQQQQH 257
Q +Q Q L QQQ Q+ QLQQ++H
Sbjct: 104 PQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKH 138
Score = 34.7 bits (78), Expect = 0.33
Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQQQQLAAQ 238
+ Q++++ Q++ Q+ + ++ PG+ Q EQQ + QQQ Q +
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQ--HE 107
Query: 239 QLVFQQQLLQMQQLQQ---QQHLLSLQRQGLISIPPGQAALPVQSL-PQAGLSPAEIQQ 293
QL Q L++QQ Q QQ L LQ++ S+ + +Q + Q L P ++Q+
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQE 166
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 118 bits (295), Expect = 2e-26
Identities = 86/199 (43%), Positives = 105/199 (52%), Gaps = 23/199 (11%)
Query: 158 QQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQ 212
QQ+ Q + L QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQ
Sbjct: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
Query: 213 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG 272
QQQQ A++QQQQQQQQQQ QQQ Q QQ QQQQ S Q L S P
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQ--------QQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Query: 273 QAALPVQSLPQAGLSPAEIQQLWKE-VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSK 331
++ LP+Q +QQ+ + + G+ + + N+ + S N
Sbjct: 681 RSPLPLQ-------QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN--P 731
Query: 332 ASPPITHHSIVNGQSSVLS 350
S P T +N Q S+L+
Sbjct: 732 CSNPNTGSGYMNSQQSLLN 750
Score = 114 bits (285), Expect = 3e-25
Identities = 107/338 (31%), Positives = 147/338 (43%), Gaps = 70/338 (20%)
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
P ++ Q QQ QQQ QQ Q QQQQ QQQQ Q QQ+Q + QQ
Sbjct: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
Query: 181 QQQQQQQQQQQQQQQQQQQQQQQQQ---------------------QQQQQQQQQQQHP- 218
QQQQQQQQQQQQQQQQQQQQQQQQQ QQ+ QQ Q P
Sbjct: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPI 700
Query: 219 ---GKQAKEQQQQQQ----------------------------QQQQLAAQQLVFQQQLL 247
G Q +QQ+Q Q QQ L QQL+ ++Q L
Sbjct: 701 AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTL 760
Query: 248 QMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDN 307
Q Q ++Q+Q LL LQ+Q L + P + + P + + V +M+
Sbjct: 761 QRQIMEQKQQLL-LQQQMLAD---AEKIAPQDQINRHLSRPPPDYK--DQRRNVGNMQPT 814
Query: 308 GIKHGGLDLTTNNSSSTTSSNTSKA-SPPITHHSIVNGQSSVLSARRDSSSHEETGASHT 366
GG SST S N+++A + P++ H+I+ SS+LS + + A
Sbjct: 815 AQYSGG--------SSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQN 866
Query: 367 --LYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRS 402
+YG+ C P S+ Q + N + L +++
Sbjct: 867 MGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQN 904
Score = 104 bits (260), Expect = 3e-22
Identities = 72/139 (51%), Positives = 82/139 (58%), Gaps = 19/139 (13%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQM +L Q + L QQQQ QQQQ Q+ ++QQ+Q QQQQQQQQQQ
Sbjct: 569 QQMPSVLPSQ--NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQ 620
Query: 187 Q-----QQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA 236
Q QQQQQQQ QQQQQQQQQQQQQQQQQQQQQQ +Q Q Q Q L
Sbjct: 621 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Query: 237 AQQLVFQQQLLQMQQLQQQ 255
L QQ+LL +QQ+Q Q
Sbjct: 681 RSPLPLQQKLL-LQQMQNQ 698
Score = 103 bits (258), Expect = 4e-22
Identities = 70/133 (52%), Positives = 80/133 (60%), Gaps = 12/133 (9%)
Query: 144 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ--- 200
QA Q + Q + Y +QQ+Q Q QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
Query: 201 -QQQQQQQ-----QQQQQQQQQHPGKQAKEQQQQQQQQQQLA---AQQLVFQQQLLQMQQ 251
QQQQQQQ QQQQQQQQQ +Q ++QQQQQQQQQQ + AQ L Q L
Sbjct: 626 AQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLP 685
Query: 252 LQQQQHLLSLQRQ 264
LQQ+ L +Q Q
Sbjct: 686 LQQKLLLQQMQNQ 698
Score = 50.8 bits (120), Expect = 4e-06
Identities = 84/408 (20%), Positives = 143/408 (35%), Gaps = 54/408 (13%)
Query: 172 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQHPGK- 220
HL +L QQ+ Q + + +Q Q QQ Q P
Sbjct: 525 HLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLL 584
Query: 221 --QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPV 278
++QQQQQQQQQQ QQ QQQ Q QQ QQQQ S+ Q
Sbjct: 585 HYTQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQSSISAQ-------------Q 628
Query: 279 QSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITH 338
Q Q+ +S + QQ ++ + + ++ + S S ++ P+
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
Query: 339 HSIVNG-QSSVLSARRDSSSHEETGASHTLYGHGVCKWPG---CESICEDFGQF--LKHL 392
++ Q+ ++ S ++ H++ G P C + G + L
Sbjct: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
Query: 393 NNEHALDDRSTAQCRVQMQVVQ-QLEIQLSKERERL---QAMMTHLHMRPSEPKPSPKPL 448
N+ + + T Q ++ Q Q L+ Q+ + E++ + HL P + K + +
Sbjct: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
Query: 449 NLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKY 508
+ T + Q P + T +T PN + H +
Sbjct: 809 GNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT-----------PNSSLLSTSHGTR- 856
Query: 509 NIPMSSEIAPNYEFYKNADVRPPFTYATL--IRQAIMESSDRQLTLNE 554
+P S N Y N P TY+ + Q + + +QL N+
Sbjct: 857 -MPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQ 903
Score = 33.9 bits (76), Expect = 0.56
Identities = 44/213 (20%), Positives = 78/213 (36%), Gaps = 18/213 (8%)
Query: 3 QESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAAR 62
Q+ + Q S++S+Q + S+ + + QQQQ Q +
Sbjct: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
Query: 63 QLLLQQQTSGLKSPKSSDKQRPLQELLPETKL----------CICGHSSGDGHP---HNT 109
Q Q L S PLQ+ L ++ + D H NT
Sbjct: 664 QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNT 723
Query: 110 FAVPVSVAMMTPQVIT--PQQMQQILQQQVLSPQQL--QALLQQQQAVMLQQQQLQEFYK 165
P P + Q +L QQ++ +Q + +++Q+Q ++LQQQ L + K
Sbjct: 724 GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEK 783
Query: 166 -KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 197
Q+Q++ L + + Q++ Q Q
Sbjct: 784 IAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQ 816
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 111 bits (278), Expect = 2e-24
Identities = 78/160 (48%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 137 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 196
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ Q
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQSAMQ 197
Query: 197 QQQQQ--QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
QQ Q QQQQQ QQQQQQQQ + QQQ QQQQQQL + QQ Q QQ QQ
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 255 QQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 294
QQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Score = 111 bits (277), Expect = 3e-24
Identities = 90/206 (43%), Positives = 105/206 (50%), Gaps = 23/206 (11%)
Query: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
SG P + P S+A+++ TPQ Q LQQ L QQ Q QQQQ LQQQQ
Sbjct: 126 SGQPPPGTSGMAPHSMAVVS--TATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQ 182
Query: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 213
Q+ ++QQ Q +QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+
Sbjct: 183 QQ--QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 214 QQQHPGKQAKEQQQQQQQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQ 262
Q +Q ++QQQQQQQQQQ A Q Q QQ +Q QQLQQ H Q
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 263 RQGLISIPPGQAALPVQSLPQAGLSP 288
PP P Q PQ+ P
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQP 326
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
Query: 187 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
Query: 244 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
Score = 95.1 bits (235), Expect = 2e-19
Identities = 82/253 (32%), Positives = 103/253 (40%), Gaps = 36/253 (14%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK--------QQEQLHLQLLQQ 178
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K QQ+Q LQ + Q
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
Query: 179 QQQQQQQQQQQQQQQQQQQQQQ----------------------QQQQQQQQQQQQQQQQ 216
Q QQQQQQQQQQQQQQQQ Q QQ QQ Q Q
Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
Query: 217 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 276
P + Q Q Q Q Q LV Q Q L Q L Q L ++ ++ PP Q +
Sbjct: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
Query: 277 PVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPI 336
Q Q + A+ Q+ V M + GG+ + +T S +S P+
Sbjct: 364 QQQ---QTAVQTAQAAQM---VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPL 417
Query: 337 THHSIVNGQSSVL 349
+ S L
Sbjct: 418 GRQPMAQVSQSSL 430
Score = 63.5 bits (153), Expect = 7e-10
Identities = 113/475 (23%), Positives = 175/475 (36%), Gaps = 48/475 (10%)
Query: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQE---LLPETKLCI 96
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q+ + + + +
Sbjct: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
Query: 97 CGHSSGDGHP---HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAV 153
H H+ + Q I Q+QQ QQQ QQ Q LQ Q +
Sbjct: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
Query: 154 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 211
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
Query: 212 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPP 271
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ P
Sbjct: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA--P 381
Query: 272 GQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSST------- 324
G + ++L Q G+ I+ + T V ++ + I G + + SS
Sbjct: 382 G-VQMITEALAQGGM---HIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPS 437
Query: 325 --TSSNTSKASPPITHHSIVNGQ------SSVLSARRDS-SSHEETGASHTLYGHGVCKW 375
T ++ PP S GQ S+V S S SS + + +
Sbjct: 438 PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
Query: 376 PGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLH 435
P S+ G +N + ++Q Q Q + +L+ QLSK E L+ M+ +
Sbjct: 498 PQNFSVPSP-GPLNTPVNPSSVMSPAGSSQAEEQ-QYLDKLK-QLSKYIEPLRRMINKID 554
Query: 436 MRPSEPKPSPKPLNLVSSVT--------MSKNMLETSPQSLPQTPTTPTAPVTPI 482
K K +L+ +T + E + + L PT P P+
Sbjct: 555 KNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPV 609
Score = 31.2 bits (69), Expect = 3.6
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 389 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 447
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 448 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 493
S + + + + Q P P P P+ Q PS + P S
Sbjct: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 111 bits (278), Expect = 2e-24
Identities = 78/160 (48%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 137 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 196
V+S Q LQ QQ + QQQQ Q+F ++QQ L QQQQQQQQQQQ Q QQ Q
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAAL-----QQQQQQQQQQQFQAQQSAMQ 197
Query: 197 QQQQQ--QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
QQ Q QQQQQ QQQQQQQQ + QQQ QQQQQQL + QQ Q QQ QQ
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 255 QQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 294
QQ +LQ Q I PP Q P P + P ++QQ+
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQP----PPSQALPQQLQQM 293
Score = 111 bits (277), Expect = 3e-24
Identities = 90/206 (43%), Positives = 105/206 (50%), Gaps = 23/206 (11%)
Query: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL 160
SG P + P S+A+++ TPQ Q LQQ L QQ Q QQQQ LQQQQ
Sbjct: 126 SGQPPPGTSGMAPHSMAVVS--TATPQTQLQ-LQQVALQQQQQQQQFQQQQQAALQQQQQ 182
Query: 161 QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 213
Q+ ++QQ Q +QQQ Q QQQQQ QQQQQQQQ Q QQQ QQQQQQ Q+
Sbjct: 183 QQ--QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR 240
Query: 214 QQQHPGKQAKEQQQQQQQQQQLAAQ-QLVFQQQLLQM----------QQLQQQQHLLSLQ 262
Q +Q ++QQQQQQQQQQ A Q Q QQ +Q QQLQQ H Q
Sbjct: 241 IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300
Query: 263 RQGLISIPPGQAALPVQSLPQAGLSP 288
PP P Q PQ+ P
Sbjct: 301 PPPQPQQPPVAQNQPSQLPPQSQTQP 326
Score = 104 bits (260), Expect = 3e-22
Identities = 80/167 (47%), Positives = 89/167 (53%), Gaps = 15/167 (8%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ QQ QQQ QQ A+ QQ QAV+ QQQQLQ+ +QQ+Q HL L Q QQQ QQ
Sbjct: 178 QQQQQQQQQQQFQAQQ-SAMQQQFQAVVQQQQQLQQ---QQQQQQHLIKLHHQNQQQIQQ 233
Query: 187 QQQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
QQQQ Q Q Q QQQQQQQQQQQQQQQQ Q P Q QQ Q Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ------ALP 287
Query: 244 QQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
QQL QM Q Q Q+ + P Q LP QS Q +S A+
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ--LPPQSQTQPLVSQAQ 332
Score = 91.7 bits (226), Expect = 2e-18
Identities = 72/198 (36%), Positives = 86/198 (43%), Gaps = 33/198 (16%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK--------QQEQLHLQLLQQ 178
QQ QQ QQ QQ QA++QQQQ + QQQQ Q K QQ+Q LQ + Q
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQ 243
Query: 179 QQQQQQQQQQQQQQQQQQQQQQ----------------------QQQQQQQQQQQQQQQQ 216
Q QQQQQQQQQQQQQQQQ Q QQ QQ Q Q
Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303
Query: 217 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 276
P + Q Q Q Q Q LV Q Q L Q L Q L ++ ++ PP Q +
Sbjct: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363
Query: 277 PVQSLPQAGLSPAEIQQL 294
Q Q + A+ Q+
Sbjct: 364 QQQ---QTAVQTAQAAQM 378
Score = 65.5 bits (158), Expect = 2e-10
Identities = 70/256 (27%), Positives = 101/256 (39%), Gaps = 17/256 (6%)
Query: 40 TSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQE---LLPETKLCI 96
T ++ V L QQQQ Q +Q LQQQ + + +Q +Q+ + + + +
Sbjct: 151 TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQL 210
Query: 97 CGHSSGDGHP---HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAV 153
H H+ + Q I Q+QQ QQQ QQ Q LQ Q +
Sbjct: 211 QQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPI 270
Query: 154 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 211
QQ +Q+ + L QL Q Q Q Q QQ Q Q Q Q Q Q
Sbjct: 271 --QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLV 328
Query: 212 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS--I 269
Q Q PG Q Q + +V QQ +Q Q QQQ + + Q +++ +
Sbjct: 329 SQAQALPG-----QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Query: 270 PPGQAALPVQSLPQAG 285
Q++LP+ S P G
Sbjct: 384 QVSQSSLPMLSSPSPG 399
Score = 31.2 bits (69), Expect = 3.6
Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 389 LKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHM-RPSEPKPSPKP 447
L H N + + Q Q+Q+ QQ + Q +++++ QA+ + +P +P P P
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282
Query: 448 LNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQG-PSVITPAS 493
S + + + + Q P P P P+ Q PS + P S
Sbjct: 283 -----SQALPQQLQQMHHTQHHQPPPQPQQP--PVAQNQPSQLPPQS 322
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 94.4 bits (233), Expect = 3e-19
Identities = 85/204 (41%), Positives = 97/204 (47%), Gaps = 26/204 (12%)
Query: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQAL-LQQQQAVMLQQQQ 159
S GH N AV S +TP+ QQ QQ QQQ QQ L LQ QQ + LQQQQ
Sbjct: 377 SQQGHT-NANAVLFSQVKVTPETHMLQQQQQAQQQQ----QQHPVLHLQPQQIMQLQQQQ 431
Query: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQ 213
Q+ ++ Q QQQQQQQQ QQQ Q QQQ QQ + QQQ Q
Sbjct: 432 QQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPF 491
Query: 214 QQQHPGKQAKEQ-QQQQQQQQQLA------------AQQLVFQQQLLQMQQLQQQQHLLS 260
QQQH +Q Q QQ Q QQQQLA QQ + QQQL +M Q QQQQ + S
Sbjct: 492 QQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQS 551
Query: 261 LQRQGLISIPPG-QAALPVQSLPQ 283
L Q +P Q PQ
Sbjct: 552 QTAPHLSQTSQALQHQVPPQQPPQ 575
Score = 94.4 bits (233), Expect = 3e-19
Identities = 77/205 (37%), Positives = 91/205 (44%), Gaps = 47/205 (22%)
Query: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHN 108
+LHLQ QQ +Q +Q QQQ S + P P + + + HPH
Sbjct: 416 VLHLQPQQIMQLQQQQ--QQQIS--QQPYPQQPPHPFSQQQQQQQ---------QAHPHQ 462
Query: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
QQ Q QQQ+ PQQL QQ Q Q Q+F++ QQ
Sbjct: 463 F----------------SQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506
Query: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-------------QQ 215
QL Q L Q QQQ QQQQQQQ QQQQ Q+ QQQQQQQ Q Q
Sbjct: 507 HQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQH 566
Query: 216 QHPGKQAKEQQQQQQ-----QQQQL 235
Q P +Q +QQQQQQ QQ QL
Sbjct: 567 QVPPQQPPQQQQQQQPPPSPQQHQL 591
Score = 90.5 bits (223), Expect = 5e-18
Identities = 118/382 (30%), Positives = 156/382 (40%), Gaps = 82/382 (21%)
Query: 3 QESATETISNSSMN-QNGMSTLSSQLDAGSRDGRSSGD------TSSEVSTVELLHLQQQ 55
+E E + N + QN ST A S++G SGD +++E S EL+
Sbjct: 194 EEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSS 253
Query: 56 QA------------------LQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCIC 97
+ L AA++ L Q + GL + ++ P L PE +
Sbjct: 254 DSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVR---- 309
Query: 98 GHSSGDGHPHNTFAVPVSVAMMTPQVIT---------------PQQMQQILQ-------- 134
G+ G + +A +P V T P + ILQ
Sbjct: 310 GNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKN 369
Query: 135 --QQVLSPQQ----LQALLQQQQAV-----MLQQQQLQEFYKKQQEQLHL---QLLQQQQ 180
QQV QQ A+L Q V MLQQQQ + ++Q LHL Q++Q QQ
Sbjct: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
Query: 181 QQQQQQQQQ----------QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ 230
QQQQQ QQ QQQQQQQQ Q QQQ Q QQQ HP +Q QQQ Q
Sbjct: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
Query: 231 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
QQ A Q F Q LQ QLQQQQ L LQ+Q + Q + Q L + + +
Sbjct: 490 PFQQQHALQQQFHQ--LQQHQLQQQQ-LAQLQQQHSLLQQQQQQQIQQQQLQR--MHQQQ 544
Query: 291 IQQLWKEVTGVH-SMEDNGIKH 311
QQ + T H S ++H
Sbjct: 545 QQQQMQSQTAPHLSQTSQALQH 566
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 94.0 bits (232), Expect = 5e-19
Identities = 81/219 (36%), Positives = 105/219 (47%), Gaps = 28/219 (12%)
Query: 56 QALQAARQLLLQQQTSGLKSPKSSDKQ--RPLQELLPETKLCICGHSSGDGHPHNTF-AV 112
+AL A R L+ + + +S++ Q R +Q+ L T L + H T A
Sbjct: 312 KALAAYRASLVSKAAA-----ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSAS 366
Query: 113 PVSVAMMTPQVITPQQ------MQQILQQQVLS---PQQLQALLQQQQAVML----QQQQ 159
P ++ P+ I P+ M QI+ ++ P + A L + Q
Sbjct: 367 PQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQ 426
Query: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219
+ + QQ Q+ LQ QQQQQQQ QQ QQQQ QQ Q QQ QQQ QQQ Q QQH
Sbjct: 427 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH-- 484
Query: 220 KQAKEQQQQQQQQQQLAAQQLVFQ-QQLLQMQQLQQQQH 257
QQQQQ QQQ+ QQL Q QQ LQ+QQLQ QH
Sbjct: 485 ----LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 519
Score = 85.5 bits (210), Expect = 2e-16
Identities = 73/220 (33%), Positives = 96/220 (43%), Gaps = 24/220 (10%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP----- 106
L Q + A+ Q L Q + +PK + P+ +++ + S G P
Sbjct: 357 LSQHGTVSASPQTLQQSLPRSI-APKPLTMRLPMNQIVTSVTIA-ANMPSNIGAPLISSM 414
Query: 107 HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK 166
T ++P V T Q Q+ QQQ QQ QQQQ +QQQQLQ
Sbjct: 415 GTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ----QQ-----QQQQMQQMQQQQLQ----- 460
Query: 167 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQQQQQQQQQQHPGKQAKE 224
Q Q+H Q+ QQ QQQ Q QQ QQQQQ QQQ QQQ QQQ QQ+ Q + +
Sbjct: 461 -QHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 519
Query: 225 QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
Q Q +Q A Q+ + Q QQH +Q Q
Sbjct: 520 QSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQ 559
Score = 79.0 bits (193), Expect = 2e-14
Identities = 50/102 (49%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
Q QQ Q Q QQQQQQQQQQ QQ QQQQ QQ Q Q +Q ++Q Q QQ L QQ
Sbjct: 432 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 491
Query: 242 FQQQLLQ---MQQLQQQQHLLSLQRQGLISIPPGQAALPVQS 280
QQQ+ Q QQLQQ+ L LQ S P + PV S
Sbjct: 492 LQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 533
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 94.0 bits (232), Expect = 5e-19
Identities = 81/219 (36%), Positives = 105/219 (47%), Gaps = 28/219 (12%)
Query: 56 QALQAARQLLLQQQTSGLKSPKSSDKQ--RPLQELLPETKLCICGHSSGDGHPHNTF-AV 112
+AL A R L+ + + +S++ Q R +Q+ L T L + H T A
Sbjct: 317 KALAAYRASLVSKAAA-----ESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSAS 371
Query: 113 PVSVAMMTPQVITPQQ------MQQILQQQVLS---PQQLQALLQQQQAVML----QQQQ 159
P ++ P+ I P+ M QI+ ++ P + A L + Q
Sbjct: 372 PQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQ 431
Query: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219
+ + QQ Q+ LQ QQQQQQQ QQ QQQQ QQ Q QQ QQQ QQQ Q QQH
Sbjct: 432 VSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH-- 489
Query: 220 KQAKEQQQQQQQQQQLAAQQLVFQ-QQLLQMQQLQQQQH 257
QQQQQ QQQ+ QQL Q QQ LQ+QQLQ QH
Sbjct: 490 ----LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 524
Score = 85.5 bits (210), Expect = 2e-16
Identities = 73/220 (33%), Positives = 96/220 (43%), Gaps = 24/220 (10%)
Query: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP----- 106
L Q + A+ Q L Q + +PK + P+ +++ + S G P
Sbjct: 362 LSQHGTVSASPQTLQQSLPRSI-APKPLTMRLPMNQIVTSVTIA-ANMPSNIGAPLISSM 419
Query: 107 HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK 166
T ++P V T Q Q+ QQQ QQ QQQQ +QQQQLQ
Sbjct: 420 GTTMVGSAPSTQVSPSVQTQQHQMQLQQQQ----QQ-----QQQQMQQMQQQQLQ----- 465
Query: 167 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQQQQQQQQQQHPGKQAKE 224
Q Q+H Q+ QQ QQQ Q QQ QQQQQ QQQ QQQ QQQ QQ+ Q + +
Sbjct: 466 -QHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQH 524
Query: 225 QQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
Q Q +Q A Q+ + Q QQH +Q Q
Sbjct: 525 QSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQ 564
Score = 79.0 bits (193), Expect = 2e-14
Identities = 50/102 (49%), Positives = 56/102 (54%), Gaps = 3/102 (2%)
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
Q QQ Q Q QQQQQQQQQQ QQ QQQQ QQ Q Q +Q ++Q Q QQ L QQ
Sbjct: 437 QTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQH 496
Query: 242 FQQQLLQ---MQQLQQQQHLLSLQRQGLISIPPGQAALPVQS 280
QQQ+ Q QQLQQ+ L LQ S P + PV S
Sbjct: 497 LQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 538
>gi|50301236 forkhead box J1 [Homo sapiens]
Length = 421
Score = 91.3 bits (225), Expect = 3e-18
Identities = 54/155 (34%), Positives = 79/155 (50%), Gaps = 16/155 (10%)
Query: 463 TSPQSLPQTPTTPTAPVTPITQGPSVI----TPASVPNVGAIRRRHSDKYNIPMSSEIAP 518
T P Q P + AP +P+ P+ + TP P R P ++
Sbjct: 57 TDPHGYHQVPGS-AAPGSPLAADPACLGQPHTPGK-PTSSCTSRSAPPGLQAPPPDDV-- 112
Query: 519 NYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVR 578
++ N V+PP++YATLI A+ S ++TL+ IY W T F YFR TW+N++R
Sbjct: 113 --DYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIR 170
Query: 579 HNLSLHKCFVRV-----ENVKGAVWTVDEVEYQKR 608
HNLSL+KCF++V E KG W +D +Y +R
Sbjct: 171 HNLSLNKCFIKVPREKDEPGKGGFWRIDP-QYAER 204
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 88.2 bits (217), Expect = 3e-17
Identities = 50/76 (65%), Positives = 54/76 (71%), Gaps = 2/76 (2%)
Query: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
L+ Q+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ A +Q QQ
Sbjct: 52 LEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQAT 111
Query: 233 QQLAAQ--QLVFQQQL 246
Q + Q QL Q L
Sbjct: 112 QGTSGQAPQLFHSQTL 127
Score = 87.0 bits (214), Expect = 6e-17
Identities = 61/119 (51%), Positives = 68/119 (57%), Gaps = 17/119 (14%)
Query: 173 LQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
L +L++QQ+QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQQ
Sbjct: 49 LSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------QQQQQQQA 96
Query: 233 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIP-PGQAAL-PVQSLPQAGLSPA 289
AA Q QQ Q Q Q S Q L + P PG L P P ++PA
Sbjct: 97 VAAAAVQQSTSQQATQGTSGQAPQLFHS---QTLTTAPLPGTTPLYPSPMTPMTPITPA 152
Score = 75.5 bits (184), Expect = 2e-13
Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 12/95 (12%)
Query: 138 LSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 197
L+PQ +Q +L++QQ Q+ +QQ+Q QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 38 LTPQPIQ---NTNSLSILEEQQRQQ---QQQQQ------QQQQQQQQQQQQQQQQQQQQQ 85
Query: 198 QQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
QQQQQQQQQQ QQ +QA + Q Q
Sbjct: 86 QQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
Score = 60.8 bits (146), Expect = 4e-09
Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 109 TFAVPVSVAMMTPQV-ITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQ 167
T +P+ MM +TPQ +Q +L QQ Q QQQQ QQQQ Q+ ++Q
Sbjct: 22 TPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQ 81
Query: 168 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQH 217
Q QQQQQQQQQQQQQ QQ QQ Q Q Q H
Sbjct: 82 Q--------QQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
Score = 45.4 bits (106), Expect = 2e-04
Identities = 37/110 (33%), Positives = 41/110 (37%), Gaps = 22/110 (20%)
Query: 106 PHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK 165
P+ T P + I +Q +Q QQQ QQ Q QQQQ
Sbjct: 33 PYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQ----------- 81
Query: 166 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 215
QQQQQQQQQQQQQQ QQ QQ Q Q Q
Sbjct: 82 -----------QQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
Score = 30.0 bits (66), Expect = 8.1
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 224 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQ 283
E+QQ+QQQQQQ Q QQ QQQQ Q+Q Q Q++
Sbjct: 53 EEQQRQQQQQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAA 99
Query: 284 AGLSPAEIQQLWKEVTG 300
A + + QQ + +G
Sbjct: 100 AAVQQSTSQQATQGTSG 116
>gi|50345831 forkhead box J3 [Homo sapiens]
Length = 622
Score = 87.8 bits (216), Expect = 3e-17
Identities = 66/249 (26%), Positives = 113/249 (45%), Gaps = 42/249 (16%)
Query: 443 PSPKPLNLVSSVTMSKNMLETSPQ-----SLPQTPTTPTAPVTPITQGPSVITPASVPNV 497
PS L + S + S ++ PQ ++ ++ T A T I++ +++ P
Sbjct: 9 PSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDP------ 62
Query: 498 GAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYS 557
N + E E ++ D +PP++YA+LI AI S +++TL+EIY
Sbjct: 63 -----------NTTLDQE-----EVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQ 106
Query: 558 WFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENVKGAVWTVDEVEYQ------ 606
W F Y+R + WKN++RHNLSL+KCF++V + KG+ W +D +
Sbjct: 107 WICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTR 166
Query: 607 -KRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQA 665
K+R++ + + T SLG ++ S LA + ++N + N +
Sbjct: 167 PKKRARSVERASTPYSIDSDSLGMECIISGSASPTLA---INTVTNKVTLYNTDQDGSDS 223
Query: 666 VHEDLNGSL 674
LN SL
Sbjct: 224 PRSSLNNSL 232
>gi|24497506 forkhead box A3 [Homo sapiens]
Length = 350
Score = 87.4 bits (215), Expect = 4e-17
Identities = 55/173 (31%), Positives = 83/173 (47%), Gaps = 16/173 (9%)
Query: 438 PSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNV 497
P P P+ PLN S +T++ P LP +P P+ P+ P P+ + P +
Sbjct: 27 PVTPVPTMAPLN--SYMTLNPLSSPYPPGGLPASPL-PSGPLAP--PAPAAPLGPTFPGL 81
Query: 498 GAIRRRHSDKYNIP-----MSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTL 552
G S Y P E+ Y A +PP++Y +LI AI ++ + LTL
Sbjct: 82 GVSGGSSSSGYGAPGPGLVHGKEMPKGYR-RPLAHAKPPYSYISLITMAIQQAPGKMLTL 140
Query: 553 NEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENV-----KGAVWTV 600
+EIY W F Y+R N W+N++RH+LS + CFV+V KG+ W +
Sbjct: 141 SEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWAL 193
>gi|31563338 forkhead box K2 [Homo sapiens]
Length = 660
Score = 83.2 bits (204), Expect = 8e-16
Identities = 68/252 (26%), Positives = 124/252 (49%), Gaps = 31/252 (12%)
Query: 421 SKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVT 480
S++RE+ +A + ++ +P SP +N+ ++ + L + ++ + P++P
Sbjct: 159 SEKREKQEA--SESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRG 216
Query: 481 PITQGPSV--ITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLI 538
+ G V + P+ + N+ A + P + + A + K+ D +PP++YA LI
Sbjct: 217 AGSSGYKVGRVMPSDL-NLMADNSQ-------PENEKEASGGDSPKD-DSKPPYSYAQLI 267
Query: 539 RQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENV 593
QAI + D+QLTLN IY+ T+ + Y+R W+N++RHNLSL++ F++V E
Sbjct: 268 VQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPG 327
Query: 594 KGAVWTVD--------EVEYQKRRSQKITG-----SPTLVKNIPTSLGYGAALNASLQAA 640
KG+ W +D E ++KRR + + P ++ P S + L+A A
Sbjct: 328 KGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGA 387
Query: 641 LAESSLPLLSNP 652
SL +P
Sbjct: 388 QTPESLSREGSP 399
>gi|4885237 forkhead box C2 [Homo sapiens]
Length = 501
Score = 82.0 bits (201), Expect = 2e-15
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 8/110 (7%)
Query: 504 HSDKYNIPMSSEIAPNYEFYKNAD---VRPPFTYATLIRQAIMESSDRQLTLNEIYSWFT 560
H ++Y+ M AP + A V+PP++Y LI AI + ++++TLN IY +
Sbjct: 44 HPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIM 103
Query: 561 RTFAYFRRNAATWKNAVRHNLSLHKCFVRV-----ENVKGAVWTVDEVEY 605
F ++R N W+N++RHNLSL++CFV+V + KG+ WT+D Y
Sbjct: 104 DRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSY 153
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 82.0 bits (201), Expect = 2e-15
Identities = 64/178 (35%), Positives = 78/178 (43%), Gaps = 13/178 (7%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
+V+ P + + L P +L Q QQ + + QQ LQ L Q +
Sbjct: 397 KVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHR 456
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ---QQQQLAAQ 238
QQQQQQQQQQQQQQQQQQQQQQQQQQQ H QQ Q QQQQ+ Q
Sbjct: 457 HPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQ 516
Query: 239 QLVF------QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Q + Q Q + Q Q+Q L P Q Q+ P+ SP E
Sbjct: 517 QFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQ----QASPEYLTSPQE 570
Score = 32.0 bits (71), Expect = 2.1
Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 25/130 (19%)
Query: 47 VELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP 106
++ LHLQ + Q +Q QQQ + + +Q+ H
Sbjct: 448 LQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQH------------------HH 489
Query: 107 HNTFAVPVSVAMMTPQVITPQQM---QQILQQQVLSPQ----QLQALLQQQQAVMLQQQQ 159
H+ + M Q T QQ QQ L V PQ Q ++ Q Q QQQ
Sbjct: 490 HHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQM 549
Query: 160 LQEFYKKQQE 169
L + QQ+
Sbjct: 550 LAQHQPSQQQ 559
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 82.0 bits (201), Expect = 2e-15
Identities = 64/178 (35%), Positives = 78/178 (43%), Gaps = 13/178 (7%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
+V+ P + + L P +L Q QQ + + QQ LQ L Q +
Sbjct: 397 KVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHR 456
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ---QQQQLAAQ 238
QQQQQQQQQQQQQQQQQQQQQQQQQQQ H QQ Q QQQQ+ Q
Sbjct: 457 HPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQ 516
Query: 239 QLVF------QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Q + Q Q + Q Q+Q L P Q Q+ P+ SP E
Sbjct: 517 QFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQ----QASPEYLTSPQE 570
Score = 32.0 bits (71), Expect = 2.1
Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 25/130 (19%)
Query: 47 VELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP 106
++ LHLQ + Q +Q QQQ + + +Q+ H
Sbjct: 448 LQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQH------------------HH 489
Query: 107 HNTFAVPVSVAMMTPQVITPQQM---QQILQQQVLSPQ----QLQALLQQQQAVMLQQQQ 159
H+ + M Q T QQ QQ L V PQ Q ++ Q Q QQQ
Sbjct: 490 HHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQM 549
Query: 160 LQEFYKKQQE 169
L + QQ+
Sbjct: 550 LAQHQPSQQQ 559
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 82.0 bits (201), Expect = 2e-15
Identities = 40/137 (29%), Positives = 97/137 (70%), Gaps = 4/137 (2%)
Query: 126 PQQMQQILQQQV-LSPQQLQALLQQQQAVMLQQQQL---QEFYKKQQEQLHLQLLQQQQQ 181
PQ+ +++ +++ L + Q L +++Q QQQ+L Q+ +KQ+E+ Q ++++Q
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
Q++++QQ+++++QQ +++Q+++++QQ +++Q++++ + +EQ++++++QQ QQL
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 242 FQQQLLQMQQLQQQQHL 258
+QQL + QQL+++Q L
Sbjct: 385 REQQLRREQQLRREQQL 401
Score = 79.7 bits (195), Expect = 9e-15
Identities = 42/141 (29%), Positives = 96/141 (68%), Gaps = 7/141 (4%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ Q++ ++Q L +Q + +QQ+ ++++ QE ++Q+E+ QL ++Q+++++QQ
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQE----ERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 187 ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
+Q++++++QQ +++Q++++++QQ +++QQ +Q + +QQ +++QQ QQL +
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 244 QQLLQMQQLQQQQHLLSLQRQ 264
QQL + QQL+++Q L Q +
Sbjct: 411 QQLRREQQLRREQQLRREQEE 431
Score = 78.2 bits (191), Expect = 3e-14
Identities = 38/132 (28%), Positives = 93/132 (70%), Gaps = 1/132 (0%)
Query: 128 QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 187
+ Q++ +++ QQ Q L ++QQ Q+++ +E ++++EQ + Q+++++QQ ++
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 188 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL-AAQQLVFQQQL 246
+Q+++++QQ +++Q++++++QQ +++Q++ +Q ++QQ +++QQL QQL +QQL
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 247 LQMQQLQQQQHL 258
+ QQL+++Q L
Sbjct: 402 RREQQLRREQQL 413
Score = 76.6 bits (187), Expect = 8e-14
Identities = 37/135 (27%), Positives = 96/135 (71%), Gaps = 6/135 (4%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL---QEFYKKQQEQLHLQLLQQQQQQQ 183
+Q++++ +Q++ +Q + +QQQ + ++QQL QE +++Q++ + ++++QQ+
Sbjct: 276 EQLRKLERQELRRERQEE---EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
++++QQ +++Q+++++QQ +++Q++++++QQ + ++ + +QQ +++QQ QQL +
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 244 QQLLQMQQLQQQQHL 258
QQL + QQL+++Q L
Sbjct: 393 QQLRREQQLRREQQL 407
Score = 75.1 bits (183), Expect = 2e-13
Identities = 38/133 (28%), Positives = 95/133 (71%), Gaps = 4/133 (3%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
+Q ++ QQ++ QQL+ ++++ ++++ Q+ ++QQE+ Q L+++Q+++++Q
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL-AAQQLVFQQQ 245
Q +++Q++++++QQ +++Q++++++QQ ++ +Q ++QQ +++QQL QQL +QQ
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRR---EQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 246 LLQMQQLQQQQHL 258
L + QQL+++Q L
Sbjct: 407 LRREQQLRREQQL 419
Score = 74.7 bits (182), Expect = 3e-13
Identities = 36/144 (25%), Positives = 100/144 (69%), Gaps = 11/144 (7%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
+ + ++ +++ +++ ++LQ +++Q L++Q+L+ ++Q+E+ Q L+++QQ
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQE--EEEQLRKLERQELRR--ERQEEEQQQQRLRREQQ 305
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL- 240
+++Q++++++QQ+++++QQ++++QQ+++++QQ + ++ +EQQ +++Q+++ QQL
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 241 ------VFQQQLLQMQQLQQQQHL 258
+QQL + QQL+++Q L
Sbjct: 366 REQEEERREQQLRREQQLRREQQL 389
Score = 72.0 bits (175), Expect = 2e-12
Identities = 30/138 (21%), Positives = 94/138 (68%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ ++ Q++ + + + +++ LQ+++ Q + Q+E+ L+ L++Q+ ++++Q
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
+++QQQQ+ +++QQ +++Q++++++QQ+++ ++ +EQQ+++++QQ Q+ +QQL
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 247 LQMQQLQQQQHLLSLQRQ 264
+ Q+ ++++ L +++
Sbjct: 352 RREQEEERREQQLRREQE 369
Score = 71.6 bits (174), Expect = 2e-12
Identities = 36/155 (23%), Positives = 104/155 (67%), Gaps = 12/155 (7%)
Query: 122 QVITPQQMQQILQQQVLSPQQL--------QALLQQQQAVMLQQQQLQEFYKKQQEQLHL 173
Q + Q+ ++ LQQ++ S QQL + LL++++ L+Q++ ++ K++QE+
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 174 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQQQQHPGKQAKEQQQQQ 229
QLL+++++++QQ+ +++Q+++ +Q+ ++++ +Q+++++Q+ +++ P ++ ++Q +
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Query: 230 QQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
++Q++ QQL +QQ + Q+L++++ L+++
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Score = 69.3 bits (168), Expect = 1e-11
Identities = 32/130 (24%), Positives = 90/130 (69%), Gaps = 1/130 (0%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ ++ Q +V ++ + +++ + ++++LQE ++Q +L + +Q ++ ++Q+
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE-EQLRKLERQE 285
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
++++Q+++QQQQ+ +++QQ +++Q+++++ ++ +EQQ++++QQ++ QQL +Q+
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 247 LQMQQLQQQQ 256
+ QQL+++Q
Sbjct: 346 RREQQLRREQ 355
Score = 64.3 bits (155), Expect = 4e-10
Identities = 31/146 (21%), Positives = 97/146 (66%), Gaps = 10/146 (6%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQE--QLHLQLLQQQQQQQQ 184
++ +Q +++ L ++ Q L ++++ ++Q+L+ Y+K++E Q QLL+++ ++++
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERET--RRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ----- 239
+Q++++Q +++++ QQ+++Q +++++++++Q +Q +E+++ QQ+++QL ++
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 240 -LVFQQQLLQMQQLQQQQHLLSLQRQ 264
++Q + ++LQQ++ L + Q
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQ 1188
Score = 63.5 bits (153), Expect = 7e-10
Identities = 33/142 (23%), Positives = 95/142 (66%), Gaps = 7/142 (4%)
Query: 125 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
T + Q+ +QQ+ Q+ + ++++ + L++++ +E QQE+ QL ++Q+++++
Sbjct: 464 TERHEQERRKQQLKRDQEEE---RRERWLKLEEEERRE----QQERREQQLRREQEERRE 516
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQ 244
Q+ ++Q+++++ QQ+ + +QQ +++Q+++++Q ++ +++ +Q++++Q+L +Q +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 245 QLLQMQQLQQQQHLLSLQRQGL 266
QLL+ ++ ++QQ L Q + L
Sbjct: 577 QLLKREEERRQQRLKREQEERL 598
Score = 63.2 bits (152), Expect = 9e-10
Identities = 49/219 (22%), Positives = 121/219 (55%), Gaps = 22/219 (10%)
Query: 48 ELLHLQQQQALQAA-RQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHP 106
EL L++++ LQ R LQ++ GL+ + ++R QE + K
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ---ERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 107 HNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK 166
H +A P + + QQ+LQ++ ++LQ ++++ Q++Q +E +
Sbjct: 887 HTLYAKPALQEQLRKE-------QQLLQEE---EEELQREEREKRRRQEQERQYREEEQL 936
Query: 167 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ 226
QQE+ QLL+++++++++Q++++Q ++ ++ QQ+++Q ++ +++++Q K+ +E++
Sbjct: 937 QQEEE--QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
Query: 227 QQQQQQQQLAAQQ------LVFQQQLLQMQQLQQQQHLL 259
+ QQ+++QL ++ +++Q + +LQQ++ L
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Score = 62.4 bits (150), Expect = 1e-09
Identities = 34/130 (26%), Positives = 83/130 (63%), Gaps = 4/130 (3%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
+Q ++ +QQ QQ + QQ + ++++ Q ++++E+ QL ++Q++++++Q
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
Q +++QQ +++QQ +++QQ +++QQ +++Q Q + +QQ +++QQ QQL +Q+
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQ----QLRREQQLRREQQLRREQQLRREQEE 431
Query: 247 LQMQQLQQQQ 256
+ +Q +Q+
Sbjct: 432 ERHEQKHEQE 441
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/144 (22%), Positives = 90/144 (62%), Gaps = 2/144 (1%)
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
PQ+ ++ QQ+ + ++ + LLQ+ + L++Q+ ++++++QL Q +++
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Q++QQ ++Q+ +++ ++++Q +Q+ +Q+Q ++Q+++ +EQ + ++++QQL Q+
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 241 VFQQQLLQMQQLQQQQHLLSLQRQ 264
++ + +QL+Q++ L+ Q
Sbjct: 1770 --DRKFREEEQLRQEREEQQLRSQ 1791
Score = 61.6 bits (148), Expect = 3e-09
Identities = 34/138 (24%), Positives = 88/138 (63%), Gaps = 4/138 (2%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ Q+ ++Q L +Q + QQ + ++++ Q+ ++Q+E+ Q L+++QQ +++Q
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
Q +++QQ +++QQ +++QQ +++QQ +++Q Q + +QQ +++Q++ +Q Q++
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQ----QLRREQQLRREQEEERHEQKHEQERR 443
Query: 247 LQMQQLQQQQHLLSLQRQ 264
Q + +Q++ L+R+
Sbjct: 444 EQRLKREQEERRDWLKRE 461
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/146 (23%), Positives = 96/146 (65%), Gaps = 6/146 (4%)
Query: 122 QVITPQQMQQILQQQVLSPQQL--QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 179
Q+ QQ+++ +QQ+ QQL + L+++Q + +Q++ + K +QE+ +L ++Q
Sbjct: 394 QLRREQQLRR--EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 239
++++ +++++ ++ +Q++++QQ ++ Q+++++++ ++ + ++QQ++++QQL +Q
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 240 LVFQQQLLQMQQLQQ--QQHLLSLQR 263
++Q L+ Q+ ++ QQ L S Q+
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQ 537
Score = 60.5 bits (145), Expect = 6e-09
Identities = 28/135 (20%), Positives = 89/135 (65%), Gaps = 4/135 (2%)
Query: 130 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 189
+Q +++ L ++ Q L ++ + Q+++ Q +++ +Q QLL+++++++++Q+ +
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 190 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 249
+Q +++++ QQ+++Q +++ +++++Q +Q +E+++ QQ+++QL ++ ++Q +
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 250 QQLQQQQHLLSLQRQ 264
Q ++++ LQRQ
Sbjct: 1198 QYREEEE----LQRQ 1208
Score = 60.1 bits (144), Expect = 7e-09
Identities = 27/136 (19%), Positives = 87/136 (63%), Gaps = 6/136 (4%)
Query: 130 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 189
+Q ++ L ++ Q L ++++ LQ+++ Q +++ +Q QLL ++++ +++Q+ +
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 190 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------LVFQ 243
+Q +++++ QQ+++Q +++ +++++Q +Q +E+++ QQ+++QL ++ +
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 244 QQLLQMQQLQQQQHLL 259
+Q + +++QQ++ L
Sbjct: 1138 RQYREEEEVQQEEEQL 1153
Score = 59.7 bits (143), Expect = 1e-08
Identities = 42/170 (24%), Positives = 98/170 (57%), Gaps = 27/170 (15%)
Query: 122 QVITPQQMQQILQQQVLSPQQL---QALLQQQQAVMLQQ----QQL---QEFYKKQQEQL 171
Q + +Q ++ +QQ+ QQL Q L ++QQ QQ QQL Q+ ++QQ +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 172 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQQQ 214
QL ++Q++++ +Q+ +Q++++Q+ +++Q Q++++QQ ++ Q+
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 215 QQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
++ + K +++++++QQ+ QQL +Q+ + Q+L++Q+ LQ++
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/138 (21%), Positives = 89/138 (64%), Gaps = 13/138 (9%)
Query: 130 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 189
QQ+ ++Q L +Q + +Q+ +Q++ ++ K++QE+ L ++++ ++ +Q+++
Sbjct: 417 QQLRREQQLRREQEEERHEQKH----EQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 190 QQQQQQQQQQ---------QQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
+QQ ++ Q++ +++++++QQ++++QQ + ++ +EQ+ ++Q++++ Q+L
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 241 VFQQQLLQMQQLQQQQHL 258
+QQL + Q+ +++Q L
Sbjct: 533 RSEQQLRREQEERREQLL 550
Score = 59.3 bits (142), Expect = 1e-08
Identities = 27/132 (20%), Positives = 86/132 (65%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ QQ+ + Q ++ L++++ Q+++ Q+ ++Q+E+ +L +Q+++++ QQ
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
+ + +QQ +++Q+++++Q +++++++ +Q +Q +++Q++++ Q L ++ QQ+L
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 247 LQMQQLQQQQHL 258
+ Q+ + +Q L
Sbjct: 591 KREQEERLEQRL 602
Score = 59.3 bits (142), Expect = 1e-08
Identities = 31/143 (21%), Positives = 87/143 (60%), Gaps = 2/143 (1%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
Q+ + QQ+ Q++ ++ + LLQ+++ L +Q+ + +++ QL Q +QQ +
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
+ ++ ++++Q Q+ ++QQ ++Q++ ++ ++++ ++ + +++ Q++QQL Q+L
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL- 1721
Query: 242 FQQQLLQMQQLQQQQHLLSLQRQ 264
+++ + +QL+Q+ L+RQ
Sbjct: 1722 -ERKFREEEQLRQETEQEQLRRQ 1743
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/164 (22%), Positives = 93/164 (56%), Gaps = 14/164 (8%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ QQ+ Q++ ++ + LLQ+++ L +Q+ + ++++QL Q ++ ++Q+ +
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 187 QQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQHPGKQAK----------EQQQQQQQQ 232
Q+ +++ +++QQ +QQ+Q Q++QQ ++Q G+Q + EQ +Q++++
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 233 QQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAAL 276
QQL+ Q+ + +L + + +Q+Q ++ + + GQ L
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Score = 58.5 bits (140), Expect = 2e-08
Identities = 27/139 (19%), Positives = 89/139 (64%), Gaps = 6/139 (4%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
+Q +Q +++ L ++ Q L ++++ Q+++ Q K+ +Q QLL ++ +++++Q
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------L 240
+++++ +++++ QQ+++Q +++++++++Q +Q +++ + QQ+++QL ++
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 241 VFQQQLLQMQQLQQQQHLL 259
++Q + ++LQQ++ L
Sbjct: 1045 ERERQYREEEELQQEEEQL 1063
Score = 58.2 bits (139), Expect = 3e-08
Identities = 31/146 (21%), Positives = 90/146 (61%), Gaps = 3/146 (2%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQ---QQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 178
Q + +Q ++ +QQ+ Q+ + QQ +Q + +QQ +E ++++QL + +
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 238
++QQ +++QQ +++QQ +++Q++++ +Q+ +Q++++Q+ +Q + + +++++ +
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 239 QLVFQQQLLQMQQLQQQQHLLSLQRQ 264
Q +QQL + Q+ ++++ L L+ +
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEE 494
Score = 57.8 bits (138), Expect = 4e-08
Identities = 26/145 (17%), Positives = 94/145 (64%), Gaps = 1/145 (0%)
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ-EQLHLQLLQQQ 179
P+ Q+ ++ +++ Q+ + LL++++ +Q+ +++ KK + +Q QLL+++
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 239
+++++ Q++++Q +++++ QQ+++Q ++++ +++Q +Q +++++ QQ+++QL ++
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 240 LVFQQQLLQMQQLQQQQHLLSLQRQ 264
+++ + +Q ++++ L + Q
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQ 1122
Score = 57.0 bits (136), Expect = 6e-08
Identities = 27/132 (20%), Positives = 84/132 (63%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ +Q L+++ ++ Q L ++Q+ +QQ +E ++++QL + +++QQ +++
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
QQ +++QQ +++QQ +++QQ +++Q++++ + + ++Q+ +++Q+ L +++
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 247 LQMQQLQQQQHL 258
+ +Q +++Q L
Sbjct: 465 ERHEQERRKQQL 476
Score = 57.0 bits (136), Expect = 6e-08
Identities = 31/142 (21%), Positives = 92/142 (64%), Gaps = 4/142 (2%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQE-QLHLQLLQQQQQQQQQ 185
Q +Q+ +QQ+ ++ + L+++ + Q+++ Q + + ++ + QLLQ+ ++QQ +
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 186 QQQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 242
+Q++ ++ ++++QQ ++Q++++ Q++QQ ++Q ++ +E++Q +Q+ +Q ++
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 243 QQQLLQMQQLQQQQHLLSLQRQ 264
+++L+ +QL+ ++ L+RQ
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQ 1767
Score = 57.0 bits (136), Expect = 6e-08
Identities = 29/128 (22%), Positives = 84/128 (65%), Gaps = 9/128 (7%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
++Q L Q+L+ ++++ + + +Q Q ++QE+ L ++Q + ++++QQ ++Q+
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQ---LRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ--QQQQQQQLAAQQ----LVFQQQLL 247
+ ++ ++++Q +Q++++QQ + Q ++ +E++Q Q++++QQL QQ ++++ L
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 248 QMQQLQQQ 255
Q+++ +Q+
Sbjct: 1829 QLEEQEQR 1836
Score = 56.6 bits (135), Expect = 8e-08
Identities = 27/127 (21%), Positives = 83/127 (65%), Gaps = 8/127 (6%)
Query: 141 QQLQALLQQQQAVMLQQQQLQEFYKKQQE--QLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 198
QQ + L ++ ++Q+ ++ Y++++E Q QLL+++++++++Q+ ++Q +++ +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 199 QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------LVFQQQLLQMQQL 252
QQ+++Q ++++++++ Q +Q +E+++ QQ+++QL ++ ++Q + ++L
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 253 QQQQHLL 259
QQ++ L
Sbjct: 1087 QQEEEQL 1093
Score = 56.2 bits (134), Expect = 1e-07
Identities = 27/123 (21%), Positives = 80/123 (65%), Gaps = 4/123 (3%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
++++ +Q + L+++Q L++Q+ + + K+++QL Q +QQ +Q + ++ ++++Q
Sbjct: 1364 EEELRHQEQGRKFLEEEQR--LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 253
Q +Q++ ++ ++++QQ ++Q++ +EQQ +Q++ ++ ++ + Q++ + QQL
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER--EEQQLH 1479
Query: 254 QQQ 256
+Q+
Sbjct: 1480 RQE 1482
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/151 (21%), Positives = 88/151 (58%), Gaps = 11/151 (7%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
Q + Q+ + ++Q L Q+ + +++ + +QQ+ ++F +++Q+ + QQ++Q
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 182 QQQQQQQQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQHPGKQAKEQQQQQQQQQ 233
+ ++ ++++Q +Q++++QQ +Q ++Q+ ++Q+Q+ + ++Q ++Q+ QQ
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 234 QLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
QL ++ ++ + +QL Q++ L RQ
Sbjct: 1612 QLRQER---DRKFREDEQLLQEREEQQLHRQ 1639
Score = 55.5 bits (132), Expect = 2e-07
Identities = 30/153 (19%), Positives = 93/153 (60%), Gaps = 10/153 (6%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
Q+ ++ ++IL+++ L P++ + L++Q+ +++ Q +++++QL Q ++ +
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 182 QQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL 235
+++Q +Q++++QQ + QQ+ +++Q Q ++Q+Q+ +Q +Q + ++Q Q++
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 236 AAQQLVFQQQLLQMQQLQQ----QQHLLSLQRQ 264
+Q ++Q++ + +Q ++ ++H+ Q++
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Score = 55.1 bits (131), Expect = 2e-07
Identities = 25/120 (20%), Positives = 81/120 (67%), Gaps = 3/120 (2%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ Q+L+++ ++ Q L ++Q+ + Q+ + +E + +QE+ Q L++++ +++++
Sbjct: 573 ERRDQLLKRE--EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK-EQQQQQQQQQQLAAQQLVFQQQ 245
QQ + ++Q++++QQQ +++QQ++++Q+ + ++ + EQ+ +++ +++ Q+L ++Q
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
Score = 55.1 bits (131), Expect = 2e-07
Identities = 26/136 (19%), Positives = 87/136 (63%), Gaps = 4/136 (2%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQ 182
Q+ +Q+L+++ ++ + Q ++ LQQ++ Q E K+++++L Q ++++ Q
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 183 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 242
Q+++Q +++ +++++Q+ ++Q +++++ QQ+++ ++ +E+++Q++++Q ++L
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Query: 243 QQQLLQMQQLQQQQHL 258
Q++ + + Q+ L
Sbjct: 1208 QKRKQRYRDEDQRSDL 1223
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/133 (24%), Positives = 85/133 (63%), Gaps = 7/133 (5%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQQQ 184
QQ+ + + + ++ Q Q+++ L+++Q QE ++K +E+ QLLQ++++QQ
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE--QLLQEREEQQL 1478
Query: 185 QQQQQQQQ-QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
+Q++ ++ +++QQ ++Q++ ++ ++Q+ + Q P ++ E++QQ +QQ+ ++ + +
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR--QRKFLQE 1536
Query: 244 QQLLQMQQLQQQQ 256
+Q L+ Q+ QQ+
Sbjct: 1537 EQQLRRQERGQQR 1549
Score = 54.7 bits (130), Expect = 3e-07
Identities = 24/126 (19%), Positives = 84/126 (66%), Gaps = 3/126 (2%)
Query: 142 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ---LLQQQQQQQQQQQQQQQQQQQQQQ 198
QL+ ++++ + + LQE +K+Q+ L + L +++++++++Q+Q++Q ++++Q
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 199 QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 258
QQ+++Q +++++++++Q +Q ++ ++ QQ+++QL ++ +++ + ++ ++++ L
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 259 LSLQRQ 264
+ Q
Sbjct: 997 QQEEEQ 1002
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/139 (19%), Positives = 95/139 (68%), Gaps = 12/139 (8%)
Query: 127 QQMQQIL--QQQVLSPQQLQALLQQQQAVMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQ 182
Q+ +Q+L +++ Q+L+ ++++ + +++QL +E K+++++ Q ++++ Q
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 183 QQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQHPGKQAKEQQQQQQQQQQLAA 237
Q+++Q ++++++++Q+ ++Q +++++ QQ+++Q ++ P K+ +++ ++Q ++++
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 238 QQLVFQQQLLQMQQLQQQQ 256
Q+ ++QLL+ +Q +++Q
Sbjct: 1178 QE---EEQLLREEQEKRRQ 1193
Score = 54.7 bits (130), Expect = 3e-07
Identities = 35/143 (24%), Positives = 82/143 (57%), Gaps = 19/143 (13%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ--------- 184
+QQ+ Q+ + LQ++Q + Q++ Q + ++ + L+Q++++QQ
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 185 ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ--QQQQQQQLAAQQ 239
++Q+ ++Q+Q+++ + +QQ ++Q+ QQQ +Q ++ +E +Q Q++++QQL Q+
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 240 -----LVFQQQLLQMQQLQQQQH 257
L + QL + ++ QQ +H
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRH 1663
Score = 54.3 bits (129), Expect = 4e-07
Identities = 27/141 (19%), Positives = 91/141 (64%), Gaps = 6/141 (4%)
Query: 127 QQMQQILQQQVLSPQQLQA---LLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 183
Q+ +Q ++Q L +Q + L ++++ +Q++ ++ K+ QE+ + + ++++
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
+++QQ++++QQ +++Q+++++Q+ ++Q+++++ +Q +QQ +++Q+ +QL+ +
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKR 552
Query: 244 QQLLQMQQLQQQQHLLSLQRQ 264
++ +++Q +++Q L Q +
Sbjct: 553 EEEKRLEQERREQRLKREQEE 573
Score = 54.3 bits (129), Expect = 4e-07
Identities = 27/130 (20%), Positives = 79/130 (60%), Gaps = 2/130 (1%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
+Q++Q ++Q LS Q+ + ++ + +Q+Q ++F + +Q+ + QQ +Q++ ++
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
++ +Q Q++++QQ +Q++ ++ +++ +Q +EQQ + + ++ ++ + Q+
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG- 1679
Query: 247 LQMQQLQQQQ 256
+ QQL++Q+
Sbjct: 1680 -EEQQLRRQE 1688
Score = 54.3 bits (129), Expect = 4e-07
Identities = 40/175 (22%), Positives = 97/175 (55%), Gaps = 15/175 (8%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ-----------QQQ 182
+QQ+ ++ + LQ++Q L++Q+L+ ++ ++EQL + Q+Q +++
Sbjct: 1697 EQQLRRQERERKFLQEEQ--QLRRQELERKFR-EEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 183 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 242
Q + ++++QQ ++Q++ ++ ++++Q +Q++++QQ +++ + ++++Q +Q +Q +
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 243 QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKE 297
QQ + +++Q L Q Q L Q Q Q S E Q+LW+E
Sbjct: 1814 PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE-KSRREEQELWQE 1867
Score = 53.9 bits (128), Expect = 5e-07
Identities = 22/116 (18%), Positives = 80/116 (68%), Gaps = 4/116 (3%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQE--FYKKQQEQLHLQLLQQQQQQQQ 184
++ QQ L+++ ++L+ L++++ L+Q++ +E +++ E+ Q L + ++Q++
Sbjct: 584 ERRQQRLKRE--QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
++QQQ +++QQ++++Q+ ++++++++ +Q+ + ++ + +Q+ +++Q+ A +++
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Score = 53.9 bits (128), Expect = 5e-07
Identities = 26/131 (19%), Positives = 83/131 (63%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ +Q ++Q ++LQ +Q ++++ QE KK +E+ LQ ++Q +++++
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
++++Q+ ++Q +++ + QQ+++Q +++++ Q +E+Q +++++ Q +QL+ +++
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 247 LQMQQLQQQQH 257
+ +Q ++Q+
Sbjct: 1070 TRRRQELERQY 1080
Score = 53.9 bits (128), Expect = 5e-07
Identities = 33/159 (20%), Positives = 92/159 (57%), Gaps = 21/159 (13%)
Query: 127 QQMQQILQQQ--VLSPQQLQALLQQQQAVMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQ 182
Q+ +Q+L+++ Q+L+ ++++ V +++QL +E K+++++L Q ++++ Q
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 183 QQQQQ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ- 238
Q+++Q ++Q++++Q++++Q +++++ Q+Q+++Q+ Q + + Q + +++ A +
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 239 -------------QLVFQQQLLQMQQLQQQQHLLSLQRQ 264
+ + QL Q Q QHLL Q++
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Score = 53.5 bits (127), Expect = 7e-07
Identities = 21/107 (19%), Positives = 74/107 (69%)
Query: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207
++QQ Q+++ ++ K+Q+E+ LQ + +QQ +++Q+++++Q +++++++ +Q++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
++Q+ +++Q + +++++++QQ+L +Q +Q L+ +++++
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Score = 53.5 bits (127), Expect = 7e-07
Identities = 25/143 (17%), Positives = 94/143 (65%), Gaps = 6/143 (4%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Q+ +Q+L+++ ++ + Q ++ LQQ++ ++ ++++E+ LQ ++Q +++++
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEE-EQLLREEREKRRLQERERQYREEEEL 1056
Query: 187 QQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
QQ+++Q ++ +++Q+ ++Q +++++ QQ+++ ++ E++++Q++++Q ++ +
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 242 FQQQLLQMQQLQQQQHLLSLQRQ 264
Q++ +++ ++++ L+RQ
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQ 1139
Score = 53.5 bits (127), Expect = 7e-07
Identities = 27/143 (18%), Positives = 89/143 (62%), Gaps = 5/143 (3%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
QQ ++ L ++ ++LQ +Q + QQ+ ++ +++E Q L++Q +++++
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 187 QQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
QQ+++Q +++++Q++++Q +++++ QQ+++ ++ +E++++Q+ ++Q ++ V
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 242 FQQQLLQMQQLQQQQHLLSLQRQ 264
Q++ +++ +++ L+RQ
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQ 1169
Score = 53.1 bits (126), Expect = 9e-07
Identities = 29/143 (20%), Positives = 93/143 (65%), Gaps = 5/143 (3%)
Query: 127 QQMQQILQQQVLSPQQL---QALLQQQQAVMLQQQ-QLQEFYKKQQEQLHLQLLQQQQQQ 182
++ Q+ +QQ+ Q+ Q L +Q++ LQQ+ + ++ +++QE+ QLL++++++
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 183 Q-QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLV 241
+ +Q++++Q+ +++Q++++ Q +++++++QQ+ + ++ EQ+ ++++ ++L ++
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 242 FQQQLLQMQQLQQQQHLLSLQRQ 264
Q+ + + +++Q LL + Q
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQ 639
Score = 53.1 bits (126), Expect = 9e-07
Identities = 28/139 (20%), Positives = 81/139 (58%), Gaps = 6/139 (4%)
Query: 134 QQQVLSPQQLQALLQ------QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 187
+QQ+ ++ Q L Q +++ L +Q+ ++++++Q+ Q +++ +++QQ
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL 1455
Query: 188 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 247
+Q++ ++ ++++Q Q++++QQ +Q++ + ++Q ++Q++ ++ Q+L Q+
Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
Query: 248 QMQQLQQQQHLLSLQRQGL 266
+ + +QQ H QR+ L
Sbjct: 1516 KFLEEEQQLHRQQRQRKFL 1534
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/132 (23%), Positives = 82/132 (62%), Gaps = 13/132 (9%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ-----LLQQQQQQQQQQQQ 188
++Q L Q+ ++Q+ L+ Q+ + + ++++QLH Q LQ++QQ ++Q++
Sbjct: 1490 EEQQLRRQERDRKFREQE---LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 189 QQQQQQQ----QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQ 244
QQ++Q + ++++Q +Q++++QQ +Q++ + +++ ++Q+Q+++ + ++
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 245 QLLQMQQLQQQQ 256
Q Q QQL+Q++
Sbjct: 1607 QEGQ-QQLRQER 1617
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/124 (20%), Positives = 80/124 (64%), Gaps = 1/124 (0%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
+Q++ +Q QA + + + Q QL+ +Q +++ + +Q+ Q+++Q+Q++++++
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGK-QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQL 252
++ + Q Q++++ +QQQ+++Q+ Q + +++ ++ +Q+L+A+ + +Q+ Q++
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801
Query: 253 QQQQ 256
++QQ
Sbjct: 802 ERQQ 805
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/144 (21%), Positives = 78/144 (54%), Gaps = 29/144 (20%)
Query: 142 QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ--- 198
QL++ +Q+ + + + QE +++QEQ + ++ + Q Q++++ +QQQ+++Q
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 199 --------------------------QQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Q+++Q + +++QQ++Q+ P ++ KEQ+++Q+++
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 233 QQLAAQQLVFQQQLLQMQQLQQQQ 256
++ Q L ++QL + ++ QQ Q
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQ 850
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/133 (19%), Positives = 81/133 (60%), Gaps = 9/133 (6%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
++Q LS Q+ ++++ + +Q++ ++F +++Q+ L+Q++ ++ ++++Q Q+
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ------LRQERHRKFREEEQLLQE 1472
Query: 194 QQQQQQQQQQQQQ---QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 250
+++QQ +Q++ + +++QQ ++Q+ K +++ + Q+ +++ ++ +Q Q +
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 251 QLQQQQHLLSLQR 263
LQ++Q L +R
Sbjct: 1533 FLQEEQQLRRQER 1545
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/138 (23%), Positives = 80/138 (57%), Gaps = 2/138 (1%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
+++ L +Q Q+Q+ + ++QQL+ + QQ + ++++Q +Q++++QQ
Sbjct: 1514 ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQH-PGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQL 252
+Q++ ++ + ++Q+ ++Q+Q+++ +Q +Q+ QQQ +Q ++ +QLLQ ++
Sbjct: 1574 RQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE- 1632
Query: 253 QQQQHLLSLQRQGLISIP 270
+QQ H R+ L P
Sbjct: 1633 EQQLHRQERDRKFLEEEP 1650
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/133 (18%), Positives = 78/133 (58%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
+Q++ + L+ ++Q +QQ+ Q F +++E+ + +++++++ Q ++++Q
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 253
Q++++ QQ Q+++ Q+ Q+++ +Q ++Q+ + Q +++ ++ + +QL+
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 254 QQQHLLSLQRQGL 266
++Q LL + + L
Sbjct: 901 KEQQLLQEEEEEL 913
Score = 50.8 bits (120), Expect = 4e-06
Identities = 24/142 (16%), Positives = 90/142 (63%), Gaps = 4/142 (2%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ----EFYKKQQEQLHLQLLQQQQQQ 182
Q+ +Q+L+++ ++ + Q ++ LQQ++ Q E K+++++ + ++++ Q
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 183 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF 242
Q+++Q +++++++++Q+ ++Q +++ + QQ+++ ++ +E+++ Q++++Q ++ +
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 243 QQQLLQMQQLQQQQHLLSLQRQ 264
Q++ + + ++ + L+RQ
Sbjct: 1058 QEEEQLLGEERETRRRQELERQ 1079
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/145 (24%), Positives = 83/145 (57%), Gaps = 11/145 (7%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQA-VMLQQQQL--QEFYKKQQEQLHLQLLQQQQQQQ 183
Q Q+ Q+Q+ ++ + +L+++Q ++QQL QE +K +E+ L+ Q++++
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR----QEREE 1785
Query: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA----AQQ 239
QQ + Q+ ++ ++++Q +Q++++QQ + QQ+ + +EQ Q ++Q+Q+L Q
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845
Query: 240 LVFQQQLLQMQQLQQQQHLLSLQRQ 264
+Q Q + +++Q L + Q
Sbjct: 1846 RAEEQFATQEKSRREEQELWQEEEQ 1870
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/131 (21%), Positives = 80/131 (61%), Gaps = 9/131 (6%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ +Q+LQ++ P + Q ++ + L+ Q+ + +++++L Q +++ +++QQ
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
+ Q+++QQ +Q + ++ ++++QQ +Q++ + +EQQ ++Q+++ ++ L
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE---------RKFL 1449
Query: 247 LQMQQLQQQQH 257
+ QQL+Q++H
Sbjct: 1450 EEEQQLRQERH 1460
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/138 (21%), Positives = 86/138 (62%), Gaps = 12/138 (8%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ----EQLHLQLLQQQQQ- 181
+Q+ Q ++Q L Q+ ++++ + Q+Q ++F +++Q ++ + L+++QQ
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEE--LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 182 ---QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ--QQQQQQQQLA 236
+++QQ +Q + ++ ++++QQ +Q++ ++ ++++Q +Q +E++ +++QQ +Q
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 237 AQQLVFQQQLLQMQQLQQ 254
++ ++QLLQ ++ QQ
Sbjct: 1460 HRKFREEEQLLQEREEQQ 1477
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/122 (20%), Positives = 80/122 (65%), Gaps = 6/122 (4%)
Query: 144 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 203
++LLQ ++ Q++ Q ++ + QL + Q+++Q++Q+Q+++ + ++Q ++Q++
Sbjct: 107 ESLLQDRR-----QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL 161
Query: 204 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQR 263
+Q+ +Q++ ++ ++ +E+++++ +++QL + + ++ +QL++++ LL L+R
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE-LLELRR 220
Query: 264 QG 265
+G
Sbjct: 221 KG 222
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/153 (22%), Positives = 86/153 (56%), Gaps = 24/153 (15%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ-------EQLHLQ-----LLQQQQQ 181
+QQV ++ + L+++Q L+Q++ ++F +++Q +QLH Q L+++QQ
Sbjct: 1436 EQQVRRQERERKFLEEEQ--QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 182 QQQQQQQQQQQQQQQQQQQQQ----QQQQQQQQQQ------QQQQHPGKQAKEQQQQQQQ 231
++Q++ ++ ++Q+ + Q+ + +++QQ +QQ Q++Q +Q + QQ++Q +
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
++ ++ + Q++ Q Q++ L+ Q
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/145 (18%), Positives = 82/145 (56%), Gaps = 10/145 (6%)
Query: 122 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 181
Q + ++ ++ +QQ+L ++ + QQQ Q+++ Q ++++E+ Q L+++ +
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 182 QQQQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQHPGKQ-AKEQQQQQQQ 231
+++++Q+ +++Q+Q ++ Q Q + + +Q + P KQ + ++Q+Q++
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 232 QQQLAAQQLVFQQQLLQMQQLQQQQ 256
+++ +L +Q++ +Q Q+++
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEE 762
Score = 48.5 bits (114), Expect = 2e-05
Identities = 22/132 (16%), Positives = 84/132 (63%), Gaps = 1/132 (0%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
+++Q + +++ L ++ LQ+++ + + Q+ + +++++Q L++++++++
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 187 QQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQ 245
+ Q+Q +++QQ Q+++++ Q+++++ +Q +E+Q ++++Q Q +QL+ +++
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 246 LLQMQQLQQQQH 257
+ +Q +++Q+
Sbjct: 949 EKRRRQERERQY 960
Score = 48.1 bits (113), Expect = 3e-05
Identities = 30/139 (21%), Positives = 76/139 (54%), Gaps = 22/139 (15%)
Query: 148 QQQQAVMLQQQQLQEFYKKQ--QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 205
QQ++ L +++ +E ++Q + + LQ L++++Q Q++++ QQ Q+++ Q+ Q+++
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 206 QQQQQQQQQQQH-----------------PGKQA---KEQQQQQQQQQQLAAQQLVFQQQ 245
+ Q+Q++ Q+ P Q KEQQ Q+++++L ++ +++
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 246 LLQMQQLQQQQHLLSLQRQ 264
Q +Q ++++ L + Q
Sbjct: 924 QEQERQYREEEQLQQEEEQ 942
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/136 (19%), Positives = 80/136 (58%), Gaps = 5/136 (3%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
++Q L Q+ + L+Q + ++++ Q +++ + + Q ++Q+++++ +++QQ
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ-- 251
+Q++ ++ ++++Q Q++++QQ ++ + +++QQ + + F++Q L+ Q+
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Query: 252 ---LQQQQHLLSLQRQ 264
L+++Q L QRQ
Sbjct: 1515 RKFLEEEQQLHRQQRQ 1530
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/161 (21%), Positives = 88/161 (54%), Gaps = 26/161 (16%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQ-QQLQEFYKKQQEQLHLQLLQQQQQQQQQ 185
++ +Q +Q+ ++LQ L +++Q ++ QQLQE QE Q ++ Q+Q++
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED---QERRRSQEQRRD 871
Query: 186 QQ----------------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK 223
Q+ Q+Q +++QQ Q+++++ Q+++++++++Q +Q +
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 224 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
E++Q QQ+++QL ++ +++ + +Q ++ + L + Q
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Score = 46.6 bits (109), Expect = 8e-05
Identities = 25/128 (19%), Positives = 75/128 (58%)
Query: 130 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 189
+Q +Q+ L ++ + ++Q+ ++ Q E ++ Q + Q LQ+++ Q+ Q++
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862
Query: 190 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 249
++ Q+Q++ Q+ + Q ++++++++ + +EQ +++QQ Q ++L +++ +
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 250 QQLQQQQH 257
+Q Q++Q+
Sbjct: 923 RQEQERQY 930
Score = 46.6 bits (109), Expect = 8e-05
Identities = 24/110 (21%), Positives = 69/110 (62%), Gaps = 8/110 (7%)
Query: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ----QQQQQQQ 203
+ +Q L+ QL++ +Q Q LQ L +QQ++ ++Q++++ QQ+ +++Q ++
Sbjct: 1246 ENEQFRQLEDSQLRD----RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 204 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ 253
++Q++ +++ ++ KQ +++++++++Q ++ ++QLLQ ++ Q
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/117 (17%), Positives = 73/117 (62%)
Query: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207
+++Q + + +EF ++Q + L +++ ++++QQQ++++Q + Q++++++ ++
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
++ ++++ ++ + Q+Q++ Q+++ ++L Q+ + Q+ +QQQ L ++Q
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/142 (21%), Positives = 81/142 (57%), Gaps = 18/142 (12%)
Query: 141 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ---------QQQQQQQQQQ 191
+Q + L Q QQ LQ +QQE+ Q ++ QQ Q ++++Q++
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 192 QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ--QQQQQQQLAAQQ--LVFQQQLL 247
+++ ++ Q+++Q ++++++++++Q ++ +E++Q Q++++Q L Q+ F+++ L
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Query: 248 QMQQ-----LQQQQHLLSLQRQ 264
+ Q+ L+++Q L +R+
Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERE 1389
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/143 (20%), Positives = 86/143 (60%), Gaps = 14/143 (9%)
Query: 127 QQMQQIL-QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQ------QEQLHLQLLQQQ 179
Q +Q +L +QQ +Q + QQ+ +++QL+ +K+ + Q QLL+++
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Query: 180 QQQQQQQQQQQQQQQQQQQ--QQQQQQQQQQQQ-----QQQQQQHPGKQAKEQQQQQQQQ 232
+++++++Q+ ++ ++++Q Q++++Q ++Q+ ++++ +H + K +++Q+ +
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 233 QQLAAQQLVFQQQLLQMQQLQQQ 255
+Q ++ + ++Q L+ Q+ +QQ
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQ 1407
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/105 (21%), Positives = 70/105 (66%), Gaps = 7/105 (6%)
Query: 155 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQ 211
L++++L E +K +E+ Q ++Q + Q++++++ ++++ ++++++ Q+++ Q+Q+
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 212 QQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQ 256
+ Q++ + E+Q+ ++++Q+ Q QQ+L + QQL+++Q
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQ----QQRLRREQQLRRKQ 310
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/148 (21%), Positives = 83/148 (56%), Gaps = 24/148 (16%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVML--QQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
Q+ Q+ L ++ Q+ + ++++ + +++QLQ + QQ Q LQ+ Q++++
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 185 QQQQQQQQQQQQQQQQQQQQ-----------QQQQQQQQQ--QQQHPGKQAKEQQQQQQQ 231
Q+Q++ Q+ + Q ++++++ Q+Q +++QQ Q++ Q +E++++++Q
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLL 259
+Q ++Q + +QLQQ++ L
Sbjct: 925 EQ---------ERQYREEEQLQQEEEQL 943
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/120 (19%), Positives = 76/120 (63%), Gaps = 1/120 (0%)
Query: 148 QQQQAVMLQQQQLQEFYKKQQEQL-HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 206
Q+++ +++QLQ + E+ + L++++ + +++ ++++QQQ++++Q + Q+
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 207 QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 266
+++++ ++++ ++ +E+ Q+++ Q+Q Q+ Q + L+ Q+L++++ Q+Q L
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Score = 44.7 bits (104), Expect = 3e-04
Identities = 31/165 (18%), Positives = 82/165 (49%), Gaps = 14/165 (8%)
Query: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
P+ QQ+ + +Q+ QQL+ Q+++ L++++ +E +++ ++ H + ++Q+
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 181 QQQQQQQQ--------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ 226
+++Q+Q Q + + +Q + + ++Q+ Q+++Q+ K+ + +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 227 QQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPP 271
+ Q Q+++ A +Q ++Q Q + RQ L + PP
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Score = 44.3 bits (103), Expect = 4e-04
Identities = 26/119 (21%), Positives = 72/119 (60%), Gaps = 4/119 (3%)
Query: 133 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 192
LQ Q Q ++Q+ Q Q +E ++ +++L + ++Q+++Q + +++QQ
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ 805
Query: 193 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQ 251
++Q+ ++++++Q+++Q+++++ K+ + ++++Q Q++ AQQL ++ LQ Q
Sbjct: 806 REQRFLPEEEEKEQRRRQRRERE----KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/159 (16%), Positives = 85/159 (53%), Gaps = 21/159 (13%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ QQ Q+ + ++ + +Q++ + Q L+E + Q+ + QL +++ Q+ Q
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 187 QQQQQQQQQQQQQ---------------------QQQQQQQQQQQQQQQQQHPGKQAKEQ 225
++++ Q+Q++ Q+ Q+Q +++QQ Q++++ ++ +E+
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 226 QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 264
+++Q+Q++Q ++ + Q++ +++ ++++ +RQ
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Score = 41.6 bits (96), Expect = 0.003
Identities = 21/140 (15%), Positives = 85/140 (60%), Gaps = 2/140 (1%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQ--QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
Q+ +Q+L+++ ++ Q ++ ++ +LQ+++ Q ++++++ + + Q+Q +
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQ 244
+ +++Q+ ++Q+++++ +++QQ + Q+++Q + + ++++QQ + F++
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434
Query: 245 QLLQMQQLQQQQHLLSLQRQ 264
+ Q+++ ++++ L ++Q
Sbjct: 1435 EEQQVRRQERERKFLEEEQQ 1454
Score = 40.8 bits (94), Expect = 0.005
Identities = 25/133 (18%), Positives = 79/133 (59%), Gaps = 10/133 (7%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
++ ++ ++ S ++ Q L ++++ +Q+ ++F +++Q L Q++++Q +
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ-------LLQEREEQPLR 1354
Query: 187 QQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ 243
+Q++ ++ ++++ + Q+Q + +++Q+ ++Q+ K KE+QQ + Q+++ +Q +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 244 QQLLQMQQLQQQQ 256
+ + QQL +Q+
Sbjct: 1415 KFREEEQQLSRQE 1427
Score = 40.4 bits (93), Expect = 0.006
Identities = 26/131 (19%), Positives = 71/131 (54%), Gaps = 12/131 (9%)
Query: 127 QQMQQILQQQVLSPQ--QLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
Q +Q Q+ P+ QL+ Q++ Q+Q+ + ++Q + +L Q+ +Q++
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 185 QQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQHPGKQAKEQQQQQQQQQQ 234
++ +Q+Q+ Q++++++ +++Q Q ++Q ++ + + + ++++QQQ+
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 235 LAAQQLVFQQQ 245
Q VFQ++
Sbjct: 231 RERQDRVFQEE 241
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/142 (19%), Positives = 76/142 (53%), Gaps = 25/142 (17%)
Query: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ- 206
+++Q Q+++L E ++ ++Q L+ +Q++ ++ +Q+Q+ Q++++++ +++Q Q
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQS 195
Query: 207 ------------QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ------------LVF 242
+Q ++++ + K +E+QQQ++++Q Q+ L
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 243 QQQLLQMQQLQQQQHLLSLQRQ 264
+++ LQ ++ Q+Q+ L + Q
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQ 277
Score = 38.9 bits (89), Expect = 0.017
Identities = 24/133 (18%), Positives = 79/133 (59%), Gaps = 4/133 (3%)
Query: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
++Q+ +Q +A + +++ +Q +E +K++ Q + ++++Q Q++++Q ++
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQ--QQQQQLAAQQLVFQQQLLQMQQ 251
Q++ ++ ++++ + Q+Q ++ + + +++++++ +++QQL Q+ +QQL Q +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER--EQQLRQDRD 1413
Query: 252 LQQQQHLLSLQRQ 264
+ ++ L RQ
Sbjct: 1414 RKFREEEQQLSRQ 1426
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/150 (18%), Positives = 78/150 (52%), Gaps = 13/150 (8%)
Query: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ--- 183
Q+ +Q+L+++ +Q + Q ++ LQ+Q+ ++ Y+ + ++ L+ + +++
Sbjct: 1178 QEEEQLLREEQEKRRQ-ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 184 ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237
+ ++ +Q +Q + Q + +Q QQ Q +QQ ++ + ++ QQ+ +
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 238 QQLVFQQQ---LLQMQQLQQQQHLLSLQRQ 264
+QL ++Q + ++ Q+++ LL +R+
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
>gi|40549454 T-cell leukemia virus enhancer factor [Homo sapiens]
Length = 431
Score = 80.9 bits (198), Expect = 4e-15
Identities = 43/100 (43%), Positives = 59/100 (59%), Gaps = 7/100 (7%)
Query: 524 KNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSL 583
K+A +PP++++ LI AI S ++ L + EIYSW F YF WKN+VRHNLSL
Sbjct: 107 KSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSL 166
Query: 584 HKCFVRVE------NVKGAVWTVDEVEYQKRRSQKITGSP 617
+KCF +VE N KG++W VD EY+ Q + P
Sbjct: 167 NKCFQKVERSHGKVNGKGSLWCVDP-EYKPNLIQALKKQP 205
>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
Length = 490
Score = 80.1 bits (196), Expect = 7e-15
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 7/104 (6%)
Query: 520 YEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRH 579
Y+ +N + +PP++++ LI AI +S ++L + +IY+W F YF WKN+VRH
Sbjct: 105 YDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRH 164
Query: 580 NLSLHKCFVRVENV------KGAVWTVDEVEYQKRRSQKITGSP 617
NLSL+KCF +V+ KG++W +D EY++ Q + +P
Sbjct: 165 NLSLNKCFKKVDKERSQSIGKGSLWCIDP-EYRQNLIQALKKTP 207
>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
Length = 468
Score = 80.1 bits (196), Expect = 7e-15
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 7/104 (6%)
Query: 520 YEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRH 579
Y+ +N + +PP++++ LI AI +S ++L + +IY+W F YF WKN+VRH
Sbjct: 105 YDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRH 164
Query: 580 NLSLHKCFVRVENV------KGAVWTVDEVEYQKRRSQKITGSP 617
NLSL+KCF +V+ KG++W +D EY++ Q + +P
Sbjct: 165 NLSLNKCFKKVDKERSQSIGKGSLWCIDP-EYRQNLIQALKKTP 207
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.123 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,587,694
Number of Sequences: 37866
Number of extensions: 1536119
Number of successful extensions: 76827
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1004
Number of HSP's successfully gapped in prelim test: 500
Number of HSP's that attempted gapping in prelim test: 13977
Number of HSP's gapped (non-prelim): 16290
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.