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Search of human proteins with 149944715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944715 protein phosphatase 1H (PP2C domain containing)
[Homo sapiens]
(514 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 1037 0.0
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 503 e-142
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 301 1e-81
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 272 6e-73
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 59 8e-09
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 59 8e-09
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 59 8e-09
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 59 8e-09
gi|7661862 protein phosphatase 1F [Homo sapiens] 57 5e-08
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 54 3e-07
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 50 5e-06
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 50 5e-06
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 50 5e-06
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 50 6e-06
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 50 6e-06
gi|4505999 protein phosphatase 1G [Homo sapiens] 49 1e-05
gi|29826282 protein phosphatase 1G [Homo sapiens] 49 1e-05
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 48 2e-05
gi|13540531 integrin-linked kinase-associated protein phosphatas... 46 9e-05
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 45 1e-04
gi|30089948 protein phosphatase 1E [Homo sapiens] 43 8e-04
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 42 0.001
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte... 37 0.043
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int... 37 0.043
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 34 0.28
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 34 0.28
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 34 0.28
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 1037 bits (2682), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADH 60
MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADH
Sbjct: 1 MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADH 60
Query: 61 IARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSK 120
IARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSK
Sbjct: 61 IARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSK 120
Query: 121 RRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDI 180
RRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDI
Sbjct: 121 RRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDI 180
Query: 181 LKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECL 240
LKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECL
Sbjct: 181 LKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECL 240
Query: 241 VIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII 300
VIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII
Sbjct: 241 VIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEII 300
Query: 301 PMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAY 360
PMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAY
Sbjct: 301 PMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAY 360
Query: 361 KTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYD 420
KTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYD
Sbjct: 361 KTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYD 420
Query: 421 LSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARG 480
LSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARG
Sbjct: 421 LSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARG 480
Query: 481 VLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS 514
VLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS
Sbjct: 481 VLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS 514
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 503 bits (1296), Expect = e-142
Identities = 270/482 (56%), Positives = 335/482 (69%), Gaps = 37/482 (7%)
Query: 27 GGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKET-RRLPWATGYAEVIN 85
G + + R + RP FL LS + + DH R + +T RRLPW+TGYAEVIN
Sbjct: 53 GSATPAKAVEARASFSRPTFLQLSPGGLRRADDHAGRAVQSPPDTGRRLPWSTGYAEVIN 112
Query: 86 AGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCH 145
AGKS HNEDQA CEV+ V+ + +VT P +E S +G+ +
Sbjct: 113 AGKSRHNEDQACCEVVYVEGRR-SVTGVP-------------------REPSRGQGLCFY 152
Query: 146 YWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRT 205
YW LFDGHAG GAA +ASRLL HI EQL+D+V+IL++ + PP CL P TP +S
Sbjct: 153 YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSP-PPLCLPTTP-GTPDSSD- 209
Query: 206 LTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNI 265
P P + + ++K++ HE LV+GA+E+AF+ MD Q+ RER + +
Sbjct: 210 -------------PSHLLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMARERRGHQV 256
Query: 266 SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHL 325
GGC AL+VI LLGK+YVANAGDSRAII+RNGEIIPMS EFTPETERQRLQ L F++P L
Sbjct: 257 EGGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPEL 316
Query: 326 LGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMAT 385
LG+EFTHLEFPRRV KELG++MLYRD NMTGWAYK IE EDL+FPL+ GEGKKARVMAT
Sbjct: 317 LGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMAT 376
Query: 386 IGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSN 445
IGVTRGLGDH LKV S + IKPFLS PEVR+YDL++Y+H DDVL+L TDGLWDV ++
Sbjct: 377 IGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTD 436
Query: 446 EEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVI 505
EVA + + L +P+D RYT AQ LV+ ARG +DRGWR+ N++LGSGDDISV+VI
Sbjct: 437 CEVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVI 496
Query: 506 PL 507
PL
Sbjct: 497 PL 498
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 301 bits (770), Expect = 1e-81
Identities = 154/286 (53%), Positives = 209/286 (73%), Gaps = 7/286 (2%)
Query: 222 PSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKL 281
PS P +F EK I E LVIGALESAF+E D I RE + GGCTAL+ + L GKL
Sbjct: 10 PSDP--QFVEEKGIRAEDLVIGALESAFQECDEVIGRELEASGQMGGCTALVAVSLQGKL 67
Query: 282 YVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQR 341
Y+ANAGDSRAI++R EI P+S EFTPETERQR+Q LAF+ P LL EFT LEFPRR++
Sbjct: 68 YMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKG 127
Query: 342 KELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHD 401
+LG+K+L+RD +M+GW+YK +E DLK+PLI+G+G++AR++ T+ V+RGLGDH L+V D
Sbjct: 128 DDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLD 187
Query: 402 SNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDP 461
+NI +KPFL S P+V + D+ + + DDV+++ATDGLWDVLSNE+VA + FLP +
Sbjct: 188 TNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPG-NQ 246
Query: 462 DDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPL 507
+DPHR++ AQ L+ +G + ++ + S DD+SV+VIPL
Sbjct: 247 EDPHRFSKLAQMLIHSTQG----KEDSLTEEGQVSYDDVSVFVIPL 288
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 272 bits (695), Expect = 6e-73
Identities = 131/241 (54%), Positives = 183/241 (75%), Gaps = 5/241 (2%)
Query: 267 GGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLL 326
GGCTAL+ + L GKLY+ANAGDSRAI++R EI P+S EFTPETERQR+Q LAF+ P LL
Sbjct: 2 GGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELL 61
Query: 327 GNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATI 386
EFT LEFPRR++ +LG+K+L+RD +M+GW+YK +E DLK+PLI+G+G++AR++ T+
Sbjct: 62 AGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTL 121
Query: 387 GVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNE 446
V+RGLGDH L+V D+NI +KPFL S P+V + D+ + + DDV+++ATDGLWDVLSNE
Sbjct: 122 AVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNE 181
Query: 447 EVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIP 506
+VA + FLP + +DPHR++ AQ L+ +G + ++ + S DD+SV+VIP
Sbjct: 182 QVAWLVRSFLPG-NQEDPHRFSKLAQMLIHSTQG----KEDSLTEEGQVSYDDVSVFVIP 236
Query: 507 L 507
L
Sbjct: 237 L 237
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327
G TA+ V+ +Y N GDSRA++ RNG++ + + P R++
Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
Query: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387
R+Q G M+ R V ++
Sbjct: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
Query: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447
V+R LGD+D K D + +S PEV Y++ + + D+ +ILA DG+WDV+SNEE
Sbjct: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
Query: 448 VAEAITQFLPNCD 460
+ E + L D
Sbjct: 254 LCEYVKSRLEVSD 266
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327
G TA+ V+ +Y N GDSRA++ RNG++ + + P R++
Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
Query: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387
R+Q G M+ R V ++
Sbjct: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
Query: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447
V+R LGD+D K D + +S PEV Y++ + + D+ +ILA DG+WDV+SNEE
Sbjct: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
Query: 448 VAEAITQFLPNCD 460
+ E + L D
Sbjct: 254 LCEYVKSRLEVSD 266
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327
G TA+ V+ +Y N GDSRA++ RNG++ + + P R++
Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
Query: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387
R+Q G M+ R V ++
Sbjct: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
Query: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447
V+R LGD+D K D + +S PEV Y++ + + D+ +ILA DG+WDV+SNEE
Sbjct: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
Query: 448 VAEAITQFLPNCD 460
+ E + L D
Sbjct: 254 LCEYVKSRLEVSD 266
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 59.3 bits (142), Expect = 8e-09
Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327
G TA+ V+ +Y N GDSRA++ RNG++ + + P R++
Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
Query: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387
R+Q G M+ R V ++
Sbjct: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
Query: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447
V+R LGD+D K D + +S PEV Y++ + + D+ +ILA DG+WDV+SNEE
Sbjct: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
Query: 448 VAEAITQFLPNCD 460
+ E + L D
Sbjct: 254 LCEYVKSRLEVSD 266
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 56.6 bits (135), Expect = 5e-08
Identities = 59/263 (22%), Positives = 101/263 (38%), Gaps = 80/263 (30%)
Query: 243 GALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPM 302
GAL AF+ D R+ + G T + + L+VA GDS+ I+++ G+++ +
Sbjct: 229 GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKL 288
Query: 303 SSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKT 362
PE + ++ + A LG +H++ W
Sbjct: 289 MEPHRPERQDEKARIEA------LGGFVSHMDC----------------------W---- 316
Query: 363 IEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLS 422
RV T+ V+R +GD ++ KP++S + L+
Sbjct: 317 ------------------RVNGTLAVSRAIGD---------VFQKPYVSGEADAASRALT 349
Query: 423 KYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVL 482
GS+D L+LA DG +DV+ ++EV + L A++LV AR
Sbjct: 350 ----GSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSG----LRVAEELVAAAR--- 398
Query: 483 KDRGWRISNDRLGSGDDISVYVI 505
GS D+I+V V+
Sbjct: 399 ----------ERGSHDNITVMVV 411
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 54.3 bits (129), Expect = 3e-07
Identities = 61/236 (25%), Positives = 98/236 (41%), Gaps = 71/236 (30%)
Query: 245 LESAFKEMDLQ-IERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIII-RNGEIIPM 302
LE +D + +E+ SY+ G T LI + L VAN GDSR ++ ++G IP+
Sbjct: 169 LEQQILSIDREMLEKLTVSYD-EAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPL 227
Query: 303 SSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKT 362
S + P ++R K + + + FN + W
Sbjct: 228 SHDHKPYQLKER---------------------------KRIKRAGGFISFNGS-W---- 255
Query: 363 IEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLS 422
RV + ++R LGD+ LK + N+ I P++ +DL
Sbjct: 256 ------------------RVQGILAMSRSLGDYPLK--NLNVVIPD-----PDILTFDLD 290
Query: 423 KYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRA 478
K + +ILA+DGLWD SNEE I + L D+PH A+ +V+++
Sbjct: 291 KLQ---PEFMILASDGLWDAFSNEEAVRFIKERL-----DEPH---FGAKSIVLQS 335
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 381 RVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLW 440
RV ++ V+R LGD D K + +S PEV + S+ D D +ILA DG+W
Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEED---DQFIILACDGIW 242
Query: 441 DVLSNEEVAEAITQFLPNCD 460
DV+ NEE+ + + L D
Sbjct: 243 DVMGNEELCDFVRSRLEVTD 262
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 381 RVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLW 440
RV ++ V+R LGD D K + +S PEV + S+ D D +ILA DG+W
Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEED---DQFIILACDGIW 242
Query: 441 DVLSNEEVAEAITQFLPNCD 460
DV+ NEE+ + + L D
Sbjct: 243 DVMGNEELCDFVRSRLEVTD 262
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 381 RVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLW 440
RV ++ V+R LGD D K + +S PEV + S+ D D +ILA DG+W
Sbjct: 259 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEED---DQFIILACDGIW 315
Query: 441 DVLSNEEVAEAITQFLPNCD 460
DV+ NEE+ + + L D
Sbjct: 316 DVMGNEELCDFVRSRLEVTD 335
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 49.7 bits (117), Expect = 6e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 142 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 201
Query: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 202 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 252
Query: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 253 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 312
Query: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 313 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 354
Query: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 355 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 408
Query: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
D L+LATDGLW+ + ++V + ++L P
Sbjct: 409 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 445
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 49.7 bits (117), Expect = 6e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 142 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 201
Query: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 202 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 252
Query: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 253 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 312
Query: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 313 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 354
Query: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 355 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 408
Query: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
D L+LATDGLW+ + ++V + ++L P
Sbjct: 409 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 445
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 49.7 bits (117), Expect = 6e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 167 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 226
Query: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 227 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 277
Query: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 278 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 337
Query: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 338 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 379
Query: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 380 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 433
Query: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
D L+LATDGLW+ + ++V + ++L P
Sbjct: 434 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 470
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 49.7 bits (117), Expect = 6e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 167 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 226
Query: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 227 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 277
Query: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 278 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 337
Query: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 338 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 379
Query: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 380 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 433
Query: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
D L+LATDGLW+ + ++V + ++L P
Sbjct: 434 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 470
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 49.7 bits (117), Expect = 6e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 201 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 260
Query: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 261 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 311
Query: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 312 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 371
Query: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 372 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 413
Query: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 414 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 467
Query: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
D L+LATDGLW+ + ++V + ++L P
Sbjct: 468 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 504
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 60/187 (32%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTP--ETERQRLQYLAFMQPHL 325
G TA++ + +L VANAGDSR ++ G+ + MS + P E E R+
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI---------- 377
Query: 326 LGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMAT 385
K G K+ M G RV
Sbjct: 378 ----------------KNAGGKV-----TMDG-----------------------RVNGG 393
Query: 386 IGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSN 445
+ ++R +GDH K + + + +S+ P++++ L+ DH + +++A DG+W+V+S+
Sbjct: 394 LNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DH---EFMVIACDGIWNVMSS 449
Query: 446 EEVAEAI 452
+EV + I
Sbjct: 450 QEVVDFI 456
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 60/187 (32%)
Query: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTP--ETERQRLQYLAFMQPHL 325
G TA++ + +L VANAGDSR ++ G+ + MS + P E E R+
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARI---------- 377
Query: 326 LGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMAT 385
K G K+ M G RV
Sbjct: 378 ----------------KNAGGKV-----TMDG-----------------------RVNGG 393
Query: 386 IGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSN 445
+ ++R +GDH K + + + +S+ P++++ L+ DH + +++A DG+W+V+S+
Sbjct: 394 LNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTD-DH---EFMVIACDGIWNVMSS 449
Query: 446 EEVAEAI 452
+EV + I
Sbjct: 450 QEVVDFI 456
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 48.1 bits (113), Expect = 2e-05
Identities = 102/419 (24%), Positives = 159/419 (37%), Gaps = 97/419 (23%)
Query: 89 STHNED---QASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEG---- 141
ST +D Q S E + +AG T S+ +S+ E QL NS E
Sbjct: 67 STEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGV 126
Query: 142 VSCHY-----WSLFDGHAGSGAA---------VVASRLLQHHITEQLQDIVDILKNSAVL 187
SC + +FDGH G A VA L+ H E ++ ++ +K +L
Sbjct: 127 ASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMK--PLL 184
Query: 188 PPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIG---A 244
P + P ++ T LR ++ E H + + A
Sbjct: 185 PILHWLKHPGDSIYKDVTSVHLDHLRV--------------YWQELLDLHMEMGLSIEEA 230
Query: 245 LESAFKEMDLQIERE-------RSSYNIS-----GGCTALIVICLLGKLYVANAGDSRAI 292
L +F+ +D I E + N+S G TA + L+VANAGD RAI
Sbjct: 231 LMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAI 290
Query: 293 I---IRNG--EIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRR---VQRKEL 344
+ NG +P++ + A+ Q L + H E R ++ + L
Sbjct: 291 LGVQEDNGMWSCLPLTRDHN-----------AWNQAELSRLKREHPESEDRTIIMEDRLL 339
Query: 345 GKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHD--- 401
G + R F D LK+ ++ + + RG L ++
Sbjct: 340 GVLIPCRAFG----------DVQLKW---------SKELQRSILERGFNTEALNIYQFTP 380
Query: 402 SNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCD 460
+ Y P+L++ PEV + L D L+LA+DGLWD+LSNE+V + L D
Sbjct: 381 PHYYTPPYLTAEPEVTYHRLRP----QDKFLVLASDGLWDMLSNEDVVRLVVGHLAEAD 435
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 45.8 bits (107), Expect = 9e-05
Identities = 62/269 (23%), Positives = 106/269 (39%), Gaps = 71/269 (26%)
Query: 245 LESAFKEMDLQIERERSSYNIS--GGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPM 302
L FK D + ++ SS + G TA V+ + LY+AN GDSRAI+ R E
Sbjct: 191 LLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNE---- 246
Query: 303 SSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKT 362
E Q+ L+ L E ++ R++ ++ G
Sbjct: 247 --------ESQKHAALS------LSKEHNPTQYEERMRIQKAG----------------- 275
Query: 363 IEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLS 422
G + RV+ + V+R +GD Y + ++S P++R L+
Sbjct: 276 ------------GNVRDGRVLGVLEVSRSIGDGQ--------YKRCGVTSVPDIRRCQLT 315
Query: 423 KYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVL 482
+D ++LA DGL+ V + EE F+ +C D+ + R
Sbjct: 316 P----NDRFILLACDGLFKVFTPEEA----VNFILSCLEDEKIQTREGKSAADARYEAAC 367
Query: 483 KDRGWRISNDRL--GSGDDISVYVIPLIH 509
R++N + GS D+++V V+ + H
Sbjct: 368 N----RLANKAVQRGSADNVTVMVVRIGH 392
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 45.4 bits (106), Expect = 1e-04
Identities = 52/215 (24%), Positives = 82/215 (38%), Gaps = 62/215 (28%)
Query: 244 ALESAFKEMDLQIERERSSYNI--SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIP 301
AL AF D ER RS + +GGCTA++++ LY+A+ GDSRA++ R G +
Sbjct: 139 ALRRAFLSAD---ERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAF 195
Query: 302 MSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYK 361
+ + P R+R + H G RRV+
Sbjct: 196 STEDHRPLRPRERERI------HAAGGTIRR----RRVE--------------------- 224
Query: 362 TIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDL 421
++ V+R LGD K +S+ PEV
Sbjct: 225 ----------------------GSLAVSRALGDFTYKEAPGRPPELQLVSAEPEV----A 258
Query: 422 SKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFL 456
+ D+ ++LA+DG+WD +S +A + L
Sbjct: 259 ALARQAEDEFMLLASDGVWDTVSGAALAGLVASRL 293
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 42.7 bits (99), Expect = 8e-04
Identities = 62/281 (22%), Positives = 109/281 (38%), Gaps = 82/281 (29%)
Query: 232 EKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRA 291
++ PH+ AL AF+ D + ++ + ++ G T ++ L+VA GDS+
Sbjct: 295 QEMFPHD--PAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQV 352
Query: 292 IIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYR 351
+++R G+ + + M+PH E + + + LG +++
Sbjct: 353 MLVRKGQAVEL------------------MKPHKPDRE------DEKQRIEALGGCVVW- 387
Query: 352 DFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLS 411
W RV ++ V+R +GD + K YI
Sbjct: 388 ---FGAW----------------------RVNGSLSVSRAIGDAEHKP-----YICGDAD 417
Query: 412 SAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAA 471
SA V G++D LILA DG +D ++ +E + ++ L + D ++ A
Sbjct: 418 SASTVL--------DGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDS----SMVA 465
Query: 472 QDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNK 512
LV AR GS D+I+V V+ L NK
Sbjct: 466 HKLVASARDA-------------GSSDNITVIVVFLRDMNK 493
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/191 (21%), Positives = 78/191 (40%), Gaps = 60/191 (31%)
Query: 265 ISGGCTALIVICLLG-KLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQP 323
++ G TA + + G +L VA+ GDSRAI+ R G+ + ++ + TPE
Sbjct: 184 LTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPE-------------- 229
Query: 324 HLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVM 383
R+ +++ + K + +N G + V
Sbjct: 230 -------------RKDEKERIKKCGGFVAWNSLG---------------------QPHVN 255
Query: 384 ATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVL 443
+ +TR +GD DLK + + PE + K H D L+L TDG+ ++
Sbjct: 256 GRLAMTRSIGDLDLKTSG--------VIAEPETK---RIKLHHADDSFLVLTTDGINFMV 304
Query: 444 SNEEVAEAITQ 454
+++E+ + + Q
Sbjct: 305 NSQEICDFVNQ 315
>gi|5174703 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform alpha [Homo sapiens]
Length = 504
Score = 37.0 bits (84), Expect = 0.043
Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 9/60 (15%)
Query: 256 IERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNG----EIIPMSSEFTPETE 311
+ERE ISGG A++ + L KLYVAN G +RA++ ++ ++ ++ + T E E
Sbjct: 158 LERE-----ISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENE 212
>gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
Length = 462
Score = 37.0 bits (84), Expect = 0.043
Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 9/60 (15%)
Query: 256 IERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNG----EIIPMSSEFTPETE 311
+ERE ISGG A++ + L KLYVAN G +RA++ ++ ++ ++ + T E E
Sbjct: 158 LERE-----ISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENE 212
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 34.3 bits (77), Expect = 0.28
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 15/185 (8%)
Query: 152 GHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAAS 211
G GSG A + + LQ + D L+ + PP P +T+ S
Sbjct: 615 GAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS 674
Query: 212 LRGGVGAPGS---PSTPPTRFFTEKKIPHECLV--IGALESAFKEMDLQIERERSSYNI- 265
GG G+PG S P F + + L+ +GA + + + I+R S NI
Sbjct: 675 PSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIF 734
Query: 266 -SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPH 324
G AL L L N +++ +G P+ +R + Q +F H
Sbjct: 735 EPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPL--------QRLQPQLRSFFHQH 786
Query: 325 LLGNE 329
LG +
Sbjct: 787 YLGGQ 791
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 34.3 bits (77), Expect = 0.28
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 15/185 (8%)
Query: 152 GHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAAS 211
G GSG A + + LQ + D L+ + PP P +T+ S
Sbjct: 615 GAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS 674
Query: 212 LRGGVGAPGS---PSTPPTRFFTEKKIPHECLV--IGALESAFKEMDLQIERERSSYNI- 265
GG G+PG S P F + + L+ +GA + + + I+R S NI
Sbjct: 675 PSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIF 734
Query: 266 -SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPH 324
G AL L L N +++ +G P+ +R + Q +F H
Sbjct: 735 EPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPL--------QRLQPQLRSFFHQH 786
Query: 325 LLGNE 329
LG +
Sbjct: 787 YLGGQ 791
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 34.3 bits (77), Expect = 0.28
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 15/185 (8%)
Query: 152 GHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAAS 211
G GSG A + + LQ + D L+ + PP P +T+ S
Sbjct: 615 GAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS 674
Query: 212 LRGGVGAPGS---PSTPPTRFFTEKKIPHECLV--IGALESAFKEMDLQIERERSSYNI- 265
GG G+PG S P F + + L+ +GA + + + I+R S NI
Sbjct: 675 PSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIF 734
Query: 266 -SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPH 324
G AL L L N +++ +G P+ +R + Q +F H
Sbjct: 735 EPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPL--------QRLQPQLRSFFHQH 786
Query: 325 LLGNE 329
LG +
Sbjct: 787 YLGGQ 791
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,575,466
Number of Sequences: 37866
Number of extensions: 969964
Number of successful extensions: 3778
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3642
Number of HSP's gapped (non-prelim): 124
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.