Search of human proteins with 149408122

Search of human proteins with 149408122

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149408122 RNA helicase LGP2 [Homo sapiens]
         (678 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149408122 RNA helicase LGP2 [Homo sapiens]                        1361   0.0  
gi|27886568 interferon induced with helicase C domain 1 [Homo sa...   510   e-144
gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [...   309   5e-84
gi|29294649 dicer1 [Homo sapiens]                                      97   6e-20
gi|29294651 dicer1 [Homo sapiens]                                      97   6e-20
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]     74   4e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    51   3e-06
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...    50   9e-06
gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo sap...    46   1e-04
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...    44   4e-04
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...    44   4e-04
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...    44   4e-04
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...    44   4e-04
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...    44   5e-04
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...    44   6e-04
gi|116812616 RecQ protein-like 4 [Homo sapiens]                        42   0.001
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...    42   0.001
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom...    42   0.002
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    41   0.003
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...    41   0.004
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       41   0.004
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...    40   0.005
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    40   0.005
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    40   0.007
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...    40   0.007
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...    40   0.007
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...    40   0.007
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...    40   0.007
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    40   0.009
gi|40217847 activating signal cointegrator 1 complex subunit 3-l...    40   0.009

>gi|149408122 RNA helicase LGP2 [Homo sapiens]
          Length = 678

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 678/678 (100%), Positives = 678/678 (100%)

Query: 1   MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV 60
           MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV
Sbjct: 1   MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV 60

Query: 61  TQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHV 120
           TQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHV
Sbjct: 61  TQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHV 120

Query: 121 ELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDG 180
           ELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDG
Sbjct: 121 ELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDG 180

Query: 181 AINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQI 240
           AINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQI
Sbjct: 181 AINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQI 240

Query: 241 HDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAV 300
           HDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAV
Sbjct: 241 HDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAV 300

Query: 301 DALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQR 360
           DALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQR
Sbjct: 301 DALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQR 360

Query: 361 QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ 420
           QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ
Sbjct: 361 QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ 420

Query: 421 QEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYA 480
           QEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYA
Sbjct: 421 QEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYA 480

Query: 481 FVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQR 540
           FVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQR
Sbjct: 481 FVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQR 540

Query: 541 ENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKV 600
           ENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKV
Sbjct: 541 ENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKV 600

Query: 601 FKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVP 660
           FKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVP
Sbjct: 601 FKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVP 660

Query: 661 DFDFLQHCAENLSDLSLD 678
           DFDFLQHCAENLSDLSLD
Sbjct: 661 DFDFLQHCAENLSDLSLD 678


>gi|27886568 interferon induced with helicase C domain 1 [Homo
            sapiens]
          Length = 1025

 Score =  510 bits (1314), Expect = e-144
 Identities = 293/717 (40%), Positives = 428/717 (59%), Gaps = 52/717 (7%)

Query: 1    MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGA----KVVVLVNR 56
            ++LR YQ EV  PALEGKNIII LPTG+GKTR A Y+AK HL+    A    KV+VLVN+
Sbjct: 306  LQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNK 365

Query: 57   VHLVTQ-HGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPE 115
            V LV Q   +EF+  L   + V  LSGD   +  F  + +  D++I TA++L+ +L + E
Sbjct: 366  VLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLE 425

Query: 116  --EEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQ---------PLPQVL 164
              E+  V+L+ FSLI++DECHHT+K+ VYN IM  YL  KL+  +         PLPQ+L
Sbjct: 426  NGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQIL 485

Query: 165  GLTASPGTGGASKLDGAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRR 224
            GLTASPG GGA+K   A  H+L+LCANLD + I + +    QL+   Q+PCK++ +    
Sbjct: 486  GLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADAT 545

Query: 225  SQDPFGDLLKKLMDQIHDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHL 284
             +DPF + L ++M +I  + +M  +S  FGTQ YEQ  +++ + AA  G +++RV A HL
Sbjct: 546  REDPFKEKLLEIMTRIQTYCQMSPMS-DFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHL 604

Query: 285  RRYNDALLIHDTVRAVDALAALQDFYHREHVTKTQIL------------C---------- 322
            R+YN+AL I+DT+R +DA   L+ FY+ E   K  ++            C          
Sbjct: 605  RKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLK 664

Query: 323  -------AERRLLALFDDRKNELAHLATHGP-ENPKLEMLEKILQRQFS-SSNSPRGIIF 373
                    +R L+ LF +    L  LA +   EN KL  L   +  Q++ +  S RGIIF
Sbjct: 665  KPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIF 724

Query: 374  TRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLN 433
            T+TRQSA++L  W+ + +    V ++A  LIGAG+SS+   MTQ +Q+EVI KF+ G +N
Sbjct: 725  TKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKIN 784

Query: 434  LLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRE 493
            LL+AT+VAEEGLDI  CN+V+RYGL+TNEI+MVQARGRARAD+S Y  VA  GS  ++ E
Sbjct: 785  LLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHE 844

Query: 494  LINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQRENQRQQFPVEHVQ 553
             +N+  E +M +A+  VQ M   EY  KI +LQ  ++ ++  +  +   +  +     + 
Sbjct: 845  TVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLIT 904

Query: 554  LLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISCR 613
             LC NC V    G D+  +E  HHVN+ P F   Y + R+   + K   D++  G I C+
Sbjct: 905  FLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELY-IVRENKALQKKCADYQINGEIICK 963

Query: 614  NCGEVWGLQMIYKSVKLPVLKVRS--MLLETPQGRIQAKKWSRVPFSVPDFDFLQHC 668
             CG+ WG  M++K + LP LK+R+  ++ +    + Q KKW  +P + P+ D+ + C
Sbjct: 964  -CGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECC 1019


>gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
           [Homo sapiens]
          Length = 925

 Score =  309 bits (792), Expect = 5e-84
 Identities = 220/693 (31%), Positives = 360/693 (51%), Gaps = 50/693 (7%)

Query: 4   RSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETV---DGAKVVVLVNRVHLV 60
           R+YQ E+ +PA++GKN II  PTG GKT  +  + + HL+        KVV   N++ + 
Sbjct: 244 RNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVY 303

Query: 61  TQHGEEFRRMLDGR-WTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEH 119
            Q    F +  +   + VT +SG          +   +D++I T ++L   + + ++   
Sbjct: 304 EQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQIL---VNNLKKGTI 360

Query: 120 VELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQ-PLPQVLGLTASPGTGGASKL 178
             L++F+L++ DECH+T K   YN+IM  YL+ KL  +  PLPQV+GLTAS G G A   
Sbjct: 361 PSLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQKLGGSSGPLPQVIGLTASVGVGDAKNT 420

Query: 179 DGAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMD 238
           D A++++ +LCA+LD   I + ++   +L++   +P K +     R  D F  ++ +LM 
Sbjct: 421 DEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMR 480

Query: 239 QIHDHL-----EMPELS----RKFGTQMYEQQVVKLSEAAALAGL----QEQRV------ 279
                      ++  LS    R+FGTQ YEQ +V + +A  +  +    +E R+      
Sbjct: 481 DTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFL 540

Query: 280 YALHLRRYNDALLIHDTVRAVDALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELA 339
           Y  HLR+YNDAL+I +  R  DAL  L+DF+   +V        E+ L   F+++  EL 
Sbjct: 541 YTSHLRKYNDALIISEHARMKDALDYLKDFF--SNVRAAGFDEIEQDLTQRFEEKLQELE 598

Query: 340 HLATH-GPENPKLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDI 398
            ++     ENPKLE L  ILQ ++  +     I+F +TR    +L  W++    L    +
Sbjct: 599 SVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSF--L 656

Query: 399 RAQLLIGAGNSSQSTHMTQRDQQEVIQKFQ-DGTLNLLVATSVAEEGLDIPHCNVVVRYG 457
           +  +L G G ++Q+T MT   Q+ ++  F+  G  N+L+ATSVA+EG+DI  CN+V+ Y 
Sbjct: 657 KPGILTGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYE 716

Query: 458 LLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMDQAE 517
            + N I M+Q RGR RA  S   F+ T  +  +++E IN   E +M  ++  +Q  D+A 
Sbjct: 717 YVGNVIKMIQTRGRGRARGS-KCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAV 775

Query: 518 YQAKIRDLQQAALTKRAAQAAQRENQRQQFPV---EHVQLLCINCMVAVGHGSDLRKVEG 574
           ++ KI  +Q         +   R++Q +  PV   E+ +LLC  C     + +D+R +E 
Sbjct: 776 FREKILHIQ-------THEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEE 828

Query: 575 THHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISC--RNCGEVWGLQMIYKSVKLPV 632
            H+  +   F   + VSR P    K F  ++    I C  +NC   WG+ + YK+ ++PV
Sbjct: 829 CHYTVLGDAFKECF-VSR-PHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPV 886

Query: 633 LKVRSMLLETPQGRIQA--KKWSRVPFSVPDFD 663
           +K+ S ++E     +Q    KW    F    FD
Sbjct: 887 IKIESFVVEDIATGVQTLYSKWKDFHFEKIPFD 919


>gi|29294649 dicer1 [Homo sapiens]
          Length = 1922

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 140/544 (25%), Positives = 237/544 (43%), Gaps = 88/544 (16%)

Query: 4   RSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETV------DGAKVVVLVNRV 57
           R YQ E++  AL+  N I+ L TG+GKT  A  + K     +      +G + V LVN  
Sbjct: 45  RKYQVELLEAALD-HNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSA 103

Query: 58  HLVTQHGEEFRRMLD---GRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSP 114
           + V Q     R   D   G ++   ++             + H +LI T  +    L   
Sbjct: 104 NQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTK-HQVLIMTCYVALNVL--- 159

Query: 115 EEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTAS--PGT 172
            +  ++ L+  +L+V DECH    D  Y  IM        +     P++LGLTAS   G 
Sbjct: 160 -KNGYLSLSDINLLVFDECHLAILDHPYREIMKL-----CENCPSCPRILGLTASILNGK 213

Query: 173 GGASKLDGAINHVLQLC-ANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGD 231
               +L+  I  + ++  +N +T   +        L  ++ QPC+    C      PF D
Sbjct: 214 CDPEELEEKIQKLEKILKSNAETATDLVV------LDRYTSQPCEIVVDC-----GPFTD 262

Query: 232 ---LLKKLMDQIHDHLE------MPELSRKFGTQMYEQQVVKLSEAAAL----------A 272
              L ++L+ ++ + L       +   S++  + +  +Q++    A  +          A
Sbjct: 263 RSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVA 322

Query: 273 GL--QEQRVYALHLRR--YNDALLIHDT-VRAVDAL-------AALQDFYHREHVTKTQI 320
           G+  +E + Y  H +   +   LL  DT +R + AL       A+L   +    V K   
Sbjct: 323 GMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLE 382

Query: 321 LCA-----ERRLLALFD--DRKNELAHLATHGPENPKLEMLEKILQRQFSSSNSPR---- 369
           +       ER+     +  + +N+  +++    E+   +  E+I +++   +N P     
Sbjct: 383 ILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDED--EEIEEKEKPETNFPSPFTN 440

Query: 370 ---GIIFTRTRQSAHSLLLWLQQ--QQGLQTVDIRAQLLIGAGNSSQSTHMTQ-----RD 419
              GIIF   R +A  L   +++  +Q  +   I +  + G G         Q     R 
Sbjct: 441 ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRK 500

Query: 420 QQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVY 479
           Q+EV++KF+    NLL+ATS+ EEG+DIP CN+VVR+ L T   S VQ++GRARA  S Y
Sbjct: 501 QEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNY 560

Query: 480 AFVA 483
             +A
Sbjct: 561 IMLA 564


>gi|29294651 dicer1 [Homo sapiens]
          Length = 1922

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 140/544 (25%), Positives = 237/544 (43%), Gaps = 88/544 (16%)

Query: 4   RSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETV------DGAKVVVLVNRV 57
           R YQ E++  AL+  N I+ L TG+GKT  A  + K     +      +G + V LVN  
Sbjct: 45  RKYQVELLEAALD-HNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSA 103

Query: 58  HLVTQHGEEFRRMLD---GRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSP 114
           + V Q     R   D   G ++   ++             + H +LI T  +    L   
Sbjct: 104 NQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTK-HQVLIMTCYVALNVL--- 159

Query: 115 EEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTAS--PGT 172
            +  ++ L+  +L+V DECH    D  Y  IM        +     P++LGLTAS   G 
Sbjct: 160 -KNGYLSLSDINLLVFDECHLAILDHPYREIMKL-----CENCPSCPRILGLTASILNGK 213

Query: 173 GGASKLDGAINHVLQLC-ANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGD 231
               +L+  I  + ++  +N +T   +        L  ++ QPC+    C      PF D
Sbjct: 214 CDPEELEEKIQKLEKILKSNAETATDLVV------LDRYTSQPCEIVVDC-----GPFTD 262

Query: 232 ---LLKKLMDQIHDHLE------MPELSRKFGTQMYEQQVVKLSEAAAL----------A 272
              L ++L+ ++ + L       +   S++  + +  +Q++    A  +          A
Sbjct: 263 RSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVA 322

Query: 273 GL--QEQRVYALHLRR--YNDALLIHDT-VRAVDAL-------AALQDFYHREHVTKTQI 320
           G+  +E + Y  H +   +   LL  DT +R + AL       A+L   +    V K   
Sbjct: 323 GMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLE 382

Query: 321 LCA-----ERRLLALFD--DRKNELAHLATHGPENPKLEMLEKILQRQFSSSNSPR---- 369
           +       ER+     +  + +N+  +++    E+   +  E+I +++   +N P     
Sbjct: 383 ILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDED--EEIEEKEKPETNFPSPFTN 440

Query: 370 ---GIIFTRTRQSAHSLLLWLQQ--QQGLQTVDIRAQLLIGAGNSSQSTHMTQ-----RD 419
              GIIF   R +A  L   +++  +Q  +   I +  + G G         Q     R 
Sbjct: 441 ILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRK 500

Query: 420 QQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVY 479
           Q+EV++KF+    NLL+ATS+ EEG+DIP CN+VVR+ L T   S VQ++GRARA  S Y
Sbjct: 501 QEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNY 560

Query: 480 AFVA 483
             +A
Sbjct: 561 IMLA 564


>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
          Length = 2048

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 48/153 (31%), Positives = 77/153 (50%), Gaps = 15/153 (9%)

Query: 348 NPKLEMLEKILQRQFSSSNSP----------RGIIFTRTRQSAHSLLLWLQQQQGLQTVD 397
           +PKL+ LE+++   F S N+           R +IF+  R S   +   L Q Q +    
Sbjct: 447 HPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPI---- 502

Query: 398 IRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYG 457
           IR    +G  +   +   TQ++Q EV+++F+DG  N LV+T V EEGLDI   ++++ + 
Sbjct: 503 IRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFD 562

Query: 458 LLTNEISMVQARGR-ARADQSVYAFVATEGSRE 489
              + I +VQ  GR  R  Q     + +EG  E
Sbjct: 563 SQKSPIRLVQRMGRTGRKRQGRIVIILSEGREE 595



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 1/63 (1%)

Query: 3   LRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQ 62
           +R YQ  +   AL   N ++ LPTG GKT  AA V           KVV +     LVTQ
Sbjct: 91  VRDYQLHISRAALFC-NTLVCLPTGLGKTFIAAVVMYNFYRWFPSGKVVFMAPTKPLVTQ 149

Query: 63  HGE 65
             E
Sbjct: 150 QIE 152


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 47/154 (30%), Positives = 74/154 (48%), Gaps = 13/154 (8%)

Query: 378 QSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLL 435
           Q + S+++++ +Q+     D   + L+ A     S H  + Q D+  +I  F++GT  LL
Sbjct: 617 QESGSVIIFVDKQEH---ADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLL 673

Query: 436 VATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR-ARADQSVYAFV-ATEGSRELKRE 493
           VATSVA  GLD+ H  +VV Y    +    V   GR  RA    YA+   TE       +
Sbjct: 674 VATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGD 733

Query: 494 LINEALETLMEQAVAAVQKM-----DQAEYQAKI 522
           +I +ALE         ++K+     DQ + + KI
Sbjct: 734 II-KALELSGTAVPPDLEKLWSDFKDQQKAEGKI 766



 Score = 30.0 bits (66), Expect = 7.3
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 11/106 (10%)

Query: 7   QWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRH------LETVDGAKVVVLVNRVHL- 59
           Q + I   + G+++I    TG+GKT A      RH      LE  +G   V++     L 
Sbjct: 399 QTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELA 458

Query: 60  --VTQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICT 103
             +T+  ++F + L  R  V  + G  G       L R  ++++CT
Sbjct: 459 LQITKECKKFSKTLGLR--VVCVYGGTGISEQIAELKRGAEIIVCT 502


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 60/290 (20%), Positives = 115/290 (39%), Gaps = 51/290 (17%)

Query: 297 VRAVDALAALQDFYHREHVTKTQILCAERRLLALFD----DRKNELAHLATHGP------ 346
           V  +D    + D Y  E + +   +C+  R   LF     D   +LA ++   P      
Sbjct: 367 VLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN 426

Query: 347 --------------------ENPKLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLW 386
                               E  +  ++  +L R F+       ++FT+T++ AH + + 
Sbjct: 427 SNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTD----HVMLFTQTKKQAHRMHIL 482

Query: 387 LQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLD 446
           L    GLQ  ++        GN SQ+  +      E +++F+D  +++LVAT VA  GLD
Sbjct: 483 LGLM-GLQVGELH-------GNLSQTQRL------EALRRFKDEQIDILVATDVAARGLD 528

Query: 447 IPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALETLMEQA 506
           I     V+ + +       V   GR          V+  G  E  R+++ E ++      
Sbjct: 529 IEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDE--RKMLKEIVKAAKAPV 586

Query: 507 VAAVQKMDQ-AEYQAKIRDLQQAALTKRAAQAAQRENQRQQFPVEHVQLL 555
            A +   D   +++ KI  +++        +A ++E Q+ +  +   + L
Sbjct: 587 KARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRL 636


>gi|154759257 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Homo
           sapiens]
          Length = 666

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 34/182 (18%)

Query: 351 LEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSS 410
           L +L  +L+  FS     R + FT +R+++H L L +Q   G+   +  ++   G G   
Sbjct: 493 LVVLHLVLEMGFS-----RVLCFTNSRENSHRLFLLVQAFGGVDVAEFSSRY--GPGQ-- 543

Query: 411 QSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARG 470
                    ++ ++++F+ G + LL++T     G+D+    +VV Y       + V   G
Sbjct: 544 ---------RRMILKQFEQGKIQLLISTDATARGIDVQGVELVVNYDAPQYLRTYVHRVG 594

Query: 471 R-ARADQSVYAF--------------VATEGSRELKR-ELINEALETLMEQAVAAVQKMD 514
           R ARA ++  AF              +   G+ EL+R EL ++ L+ L+ +   A+ +++
Sbjct: 595 RTARAGKTGQAFTLLLKVQERRFLRMLTEAGAPELQRHELSSKLLQPLVPRYEEALSQLE 654

Query: 515 QA 516
           ++
Sbjct: 655 ES 656


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 7/138 (5%)

Query: 384 LLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLLVATSVA 441
           L++++ ++G  +++     L   G +  S H   +QRD++E + +F+ G   +LVAT+VA
Sbjct: 443 LVFVETKKGADSLE---DFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 499

Query: 442 EEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALET 501
             GLDI +   V+ + L ++    V   GR     ++   +AT    E    +  + L+ 
Sbjct: 500 ARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL--GLATSFFNEKNMNITKDLLDL 557

Query: 502 LMEQAVAAVQKMDQAEYQ 519
           L+E        ++   Y+
Sbjct: 558 LVEAKQEVPSWLENMAYE 575


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 7/138 (5%)

Query: 384 LLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLLVATSVA 441
           L++++ ++G  +++     L   G +  S H   +QRD++E + +F+ G   +LVAT+VA
Sbjct: 443 LVFVETKKGADSLE---DFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 499

Query: 442 EEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALET 501
             GLDI +   V+ + L ++    V   GR     ++   +AT    E    +  + L+ 
Sbjct: 500 ARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNL--GLATSFFNEKNMNITKDLLDL 557

Query: 502 LMEQAVAAVQKMDQAEYQ 519
           L+E        ++   Y+
Sbjct: 558 LVEAKQEVPSWLENMAYE 575


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 3/81 (3%)

Query: 400 AQLLIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYG 457
           A LL   G ++   H  M+Q  +   + KF+    ++L+AT VA  GLDIPH +VVV + 
Sbjct: 280 ALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFD 339

Query: 458 LLTNEISMVQARGR-ARADQS 477
           + T+    +   GR ARA +S
Sbjct: 340 IPTHSKDYIHRVGRTARAGRS 360



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 7   QWEVIMPALEGKNIIIWLPTGAGKTRAAAY-VAKRHLETVDGAKVVVLVNRVHLVTQHGE 65
           Q E I  AL+G++II    TG+GKT A A  +    LET      +VL     L  Q  E
Sbjct: 51  QIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISE 110

Query: 66  EFRRM 70
           +F  +
Sbjct: 111 QFEAL 115


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 29/162 (17%)

Query: 295 DTVRAVDALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEML 354
           DT+R +  LA  Q F+       + +   ++R L +               PE  K   L
Sbjct: 191 DTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLV---------------PEKVKDAYL 235

Query: 355 EKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH 414
             ++QR          IIFT T ++   L + L++     TV + +              
Sbjct: 236 VHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFS-FPTVALHSM------------- 281

Query: 415 MTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRY 456
           M Q+++   + KF+     +L+AT VA  GLDIP   VV+ +
Sbjct: 282 MKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINH 323


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 18/64 (28%), Positives = 37/64 (57%)

Query: 409 SSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQA 468
           SS    M Q++++ ++++F+ G   +L++T V   GLD+P  ++++ Y L  N    +  
Sbjct: 305 SSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHR 364

Query: 469 RGRA 472
            GR+
Sbjct: 365 IGRS 368


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 7/138 (5%)

Query: 384 LLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLLVATSVA 441
           L++++ ++G  +++     L   G +  S H   +QRD++E + +F+ G   +LVAT+VA
Sbjct: 445 LVFVETKKGADSLE---DFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 501

Query: 442 EEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALET 501
             GLDI +   V+ + L ++    V   GR     ++   +AT    E    +  + L+ 
Sbjct: 502 ARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNL--GLATSFFNERNINITKDLLDL 559

Query: 502 LMEQAVAAVQKMDQAEYQ 519
           L+E        ++   Y+
Sbjct: 560 LVEAKQEVPSWLENMAYE 577


>gi|116812616 RecQ protein-like 4 [Homo sapiens]
          Length = 1208

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 11/111 (9%)

Query: 415 MTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARA 474
           M  R+++ V + F  G L ++VAT     GLD P    V+  GL  +  S VQA GRA  
Sbjct: 748 MCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGR 807

Query: 475 D---QSVYAFVATEGS--RELKRELINEALETLMEQAVAAVQKMDQAEYQA 520
           D      + F+  +G   REL+R +  ++ + L      AV+++ Q  + A
Sbjct: 808 DGQPAHCHLFLQPQGEDLRELRRHVHADSTDFL------AVKRLVQRVFPA 852


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 1/55 (1%)

Query: 424 IQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR-ARADQS 477
           + KF+    ++L+AT VA  GLDIPH +VVV + + T+    +   GR ARA +S
Sbjct: 257 LNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS 311



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 7   QWEVIMPALEGKNIIIWLPTGAGKTRAAAY-VAKRHLETVDGAKVVVLVNRVHLVTQHGE 65
           Q E I  AL+G++II    TG+GKT A A  +    LET      +VL     L  Q  E
Sbjct: 51  QIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISE 110

Query: 66  EFRRM 70
           +F  +
Sbjct: 111 QFEAL 115


>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
           sapiens]
          Length = 1706

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 58/247 (23%), Positives = 104/247 (42%), Gaps = 25/247 (10%)

Query: 5   SYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHG 64
           ++Q E++    + ++ +I  PT +GKT A+ Y  ++ L   D   VV +     LV Q  
Sbjct: 746 AWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQ-- 803

Query: 65  EEFRRMLDGRWTVTTLSGDMGPRAGFGHLAR--CHDLLIC-----TAELLQMALTSPEEE 117
                 ++ R+T T  +G    R   G   R  CH++L C       E  ++ L +P  +
Sbjct: 804 --VAATVENRFTKTLPAG----RTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHRQ 857

Query: 118 EHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASK 177
           + VE   +  ++ DE H+  ++     + +++ EL L   +    VL  T +        
Sbjct: 858 KWVERIRY--VIFDEVHYLGRE-----VGAKFWELLLVIIRCPFLVLSATINNPNLLTKW 910

Query: 178 LDGAINHVLQLCANLDTWCIMSPQ--NCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKK 235
           L     +  Q    ++  CI   Q   C   LQ+HS +  + Y +      + + DL K 
Sbjct: 911 LQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKN-QSYEVRLVLYGERYNDLEKH 969

Query: 236 LMDQIHD 242
           +    HD
Sbjct: 970 ICSVKHD 976


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 19/110 (17%)

Query: 364 SSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTH--MTQRDQQ 421
           S +  R IIF  T++ A  L     Q   ++               +QS H  + Q+ ++
Sbjct: 435 SGHQGRTIIFCETKKEAQEL----SQNSAIK-------------QDAQSLHGDIPQKQRE 477

Query: 422 EVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR 471
             ++ F++G+  +LVAT+VA  GLDIP  ++V++     +  S +   GR
Sbjct: 478 ITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGR 527


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 22/103 (21%), Positives = 49/103 (47%), Gaps = 14/103 (13%)

Query: 369 RGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQ 428
           + +IF  TR+       WL ++   +   +          S+    M Q+++  ++++F+
Sbjct: 274 QAVIFINTRRKVD----WLTEKMHARDFTV----------SAMHGDMDQKERDVIMREFR 319

Query: 429 DGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR 471
            G+  +L+ T +   G+D+   ++V+ Y L TN  + +   GR
Sbjct: 320 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 362


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 31/175 (17%)

Query: 361 QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ 420
           Q  S +  R IIF  T+++   + +    +Q  Q +          G+ +QS       Q
Sbjct: 383 QVYSGSEGRAIIFCETKKNVTEMAMNPHIKQNAQCLH---------GDIAQS-------Q 426

Query: 421 QEVIQK-FQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR-ARA---- 474
           +E+  K F++G+  +LVAT+VA  GLDIP  ++V++     +  S +   GR  RA    
Sbjct: 427 REITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTG 486

Query: 475 ---------DQSVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQA 520
                    ++    +V  +     KR  +   ++ +  +++ A++ +    Y A
Sbjct: 487 ICICFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAA 541



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 12/127 (9%)

Query: 13  PALEGKNIIIWLPTGAGKTRAAAYV----AKRHLETVD---GAKVVVLVNRVHLVTQHGE 65
           P  EGK++I    TG GKT + A       +R+ ET+      KV+VL     L  Q  +
Sbjct: 170 PVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAK 229

Query: 66  EFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHVELTVF 125
           +F+  +  + +V    G    ++   H+    D+L+ T   ++  L S      ++L+  
Sbjct: 230 DFKD-ITRKLSVACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQS----GRLDLSKL 284

Query: 126 SLIVVDE 132
             +V+DE
Sbjct: 285 RHVVLDE 291


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 14/103 (13%)

Query: 369 RGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQ 428
           + +IF  TR+       WL ++  +   D     L G         M Q+++  ++++F+
Sbjct: 275 QAVIFLNTRRKVD----WLTEK--MHARDFTVSALHG--------DMDQKERDVIMREFR 320

Query: 429 DGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGR 471
            G+  +L+ T +   G+D+   ++V+ Y L TN  + +   GR
Sbjct: 321 SGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGR 363


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 37/157 (23%), Positives = 73/157 (46%), Gaps = 13/157 (8%)

Query: 355 EKILQRQF--SSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQS 412
           E++ Q+ F  S S   + ++    +     +++++ Q++G    D+ A+ L   G ++ +
Sbjct: 637 ERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGC---DVLAKSLEKMGYNACT 693

Query: 413 TH--MTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTN---EISMVQ 467
            H    Q  ++  +   + G  ++LVAT VA  G+DI   ++VV Y +  N    I  + 
Sbjct: 694 LHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIG 753

Query: 468 ARGRARADQSVYAFVATEGSR---ELKRELINEALET 501
             GRA        F+  E S    ELK+ ++   + +
Sbjct: 754 RTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSS 790


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
           partial [Homo sapiens]
          Length = 1700

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 45/180 (25%), Positives = 78/180 (43%), Gaps = 19/180 (10%)

Query: 3   LRSYQWEVIMPALE-GKNIIIWLPTGAGKTRAAAYVAKRHLE---------TVDGAKVVV 52
           L   Q ++   ALE  +N+++  PTGAGKT  A     R +           VD  K++ 
Sbjct: 45  LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY 104

Query: 53  LVNRVHLVTQHGEEF-RRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMAL 111
           +     LV +    F +R+     TV  L+GD               +++CT E   +  
Sbjct: 105 IAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLCKEEISATQIIVCTPEKWDIIT 161

Query: 112 TSPEEEEHVELTVFSLIVVDECHHTHKD--TVYNVIMSQYLELKLQRAQPLPQVLGLTAS 169
               E  + +L    LIV+DE H  H D   V   ++++ +   ++  Q   +++GL+A+
Sbjct: 162 RKGGERTYTQLV--RLIVLDEIHLLHDDRGPVLEALVARAIR-NIEMTQEDVRLIGLSAT 218


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 21/149 (14%)

Query: 350 KLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNS 409
           K E L +IL+    +    R ++F  T++ A  +  +L Q++ + T  I           
Sbjct: 527 KREKLVEILR----NIGDERTMVFVETKKKADFIATFLCQEK-ISTTSIHGD-------- 573

Query: 410 SQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGL---LTNEISMV 466
                  QR++++ +  F+ G   +LVATSVA  GLDI +   V+ + L   +   +  +
Sbjct: 574 -----REQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRI 628

Query: 467 QARGRARADQSVYAFVATEGSRELKRELI 495
              GR        +F   E    L + L+
Sbjct: 629 GRTGRCGNTGRAISFFDLESDNHLAQPLV 657


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 21/149 (14%)

Query: 350 KLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNS 409
           K E L +IL+    +    R ++F  T++ A  +  +L Q++ + T  I           
Sbjct: 527 KREKLVEILR----NIGDERTMVFVETKKKADFIATFLCQEK-ISTTSIHGD-------- 573

Query: 410 SQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGL---LTNEISMV 466
                  QR++++ +  F+ G   +LVATSVA  GLDI +   V+ + L   +   +  +
Sbjct: 574 -----REQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRI 628

Query: 467 QARGRARADQSVYAFVATEGSRELKRELI 495
              GR        +F   E    L + L+
Sbjct: 629 GRTGRCGNTGRAISFFDLESDNHLAQPLV 657


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 21/149 (14%)

Query: 350 KLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNS 409
           K E L +IL+    +    R ++F  T++ A  +  +L Q++ + T  I           
Sbjct: 493 KREKLVEILR----NIGDERTMVFVETKKKADFIATFLCQEK-ISTTSIHGD-------- 539

Query: 410 SQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGL---LTNEISMV 466
                  QR++++ +  F+ G   +LVATSVA  GLDI +   V+ + L   +   +  +
Sbjct: 540 -----REQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRI 594

Query: 467 QARGRARADQSVYAFVATEGSRELKRELI 495
              GR        +F   E    L + L+
Sbjct: 595 GRTGRCGNTGRAISFFDLESDNHLAQPLV 623


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 14/97 (14%)

Query: 362 FSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQ 421
           + S    + IIF +TR++A  L + + Q               G   S  S  +T   + 
Sbjct: 333 YGSITIGQAIIFCQTRRNAKWLTVEMIQD--------------GHQVSLLSGELTVEQRA 378

Query: 422 EVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGL 458
            +IQ+F+DG   +L+ T+V   G+D+    +VV + L
Sbjct: 379 SIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDL 415


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 7/117 (5%)

Query: 403 LIGAGNSSQSTH--MTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLT 460
           LI    S +S H    QRD+++ ++ F+ G + +L+AT +A  GLD+     V  +    
Sbjct: 507 LILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPR 566

Query: 461 NEISMVQARGR-ARADQS-VYAFVATEGSRELKRELIN---EALETLMEQAVAAVQK 512
           N    V   GR  RA ++ V     T     +  ELIN    A +++ E+ V+  ++
Sbjct: 567 NIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAER 623


>gi|40217847 activating signal cointegrator 1 complex subunit 3-like
           1 [Homo sapiens]
          Length = 2136

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 19/180 (10%)

Query: 3   LRSYQWEVIMPALE-GKNIIIWLPTGAGKTRAAAYVAKRHLE---------TVDGAKVVV 52
           L   Q ++   ALE  +N+++  PTGAGKT  A     R +           VD  K++ 
Sbjct: 481 LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY 540

Query: 53  LVNRVHLVTQHGEEF-RRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMAL 111
           +     LV +    F +R+     TV  L+GD               +++CT E   +  
Sbjct: 541 IAPMRSLVQEMVGSFGKRLATYGITVAELTGD---HQLCKEEISATQIIVCTPEKWDIIT 597

Query: 112 TSPEEEEHVELTVFSLIVVDECHHTHKD--TVYNVIMSQYLELKLQRAQPLPQVLGLTAS 169
               E  + +L    LI++DE H  H D   V   ++++ +   ++  Q   +++GL+A+
Sbjct: 598 RKGGERTYTQLV--RLIILDEIHLLHDDRGPVLEALVARAIR-NIEMTQEDVRLIGLSAT 654


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,636,504
Number of Sequences: 37866
Number of extensions: 1062160
Number of successful extensions: 3279
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 3055
Number of HSP's gapped (non-prelim): 246
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.