Guide to the Human Genome
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Search of human proteins with 14670350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14670350 general transcription factor II, i isoform 1 [Homo
sapiens]
         (998 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14670350 general transcription factor II, i isoform 1 [Homo s...  1995   0.0  
gi|14670352 general transcription factor II, i isoform 2 [Homo s...  1943   0.0  
gi|14670354 general transcription factor II, i isoform 3 [Homo s...  1942   0.0  
gi|169881252 general transcription factor II, i isoform 4 [Homo ...  1890   0.0  
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]           461   e-129
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]          461   e-129
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi...   380   e-105
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap...   374   e-103
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ...   159   2e-38
gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]          131   3e-30
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap...   129   1e-29
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti...   129   2e-29
gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo ...   113   8e-25
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]     46   2e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         44   8e-04
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        39   0.024
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]        39   0.024
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    39   0.032
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    39   0.032
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    39   0.032
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    39   0.032
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    38   0.042
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         37   0.093
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    37   0.12 
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    36   0.16 
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]           36   0.16 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    35   0.27 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    35   0.27 

>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score = 1995 bits (5169), Expect = 0.0
 Identities = 998/998 (100%), Positives = 998/998 (100%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300

Query: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360
           SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420

Query: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480

Query: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540

Query: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600

Query: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660

Query: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720

Query: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780

Query: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840

Query: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900

Query: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960

Query: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998


>gi|14670352 general transcription factor II, i isoform 2 [Homo
           sapiens]
          Length = 978

 Score = 1943 bits (5034), Expect = 0.0
 Identities = 978/998 (97%), Positives = 978/998 (97%), Gaps = 20/998 (2%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           EESEDPDYYQYNIQ                    GSHHSSEGNEGTEMEVPAEDSTQHVP
Sbjct: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDSTQHVP 280

Query: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360
           SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 281 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 340

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400

Query: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 401 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 460

Query: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 461 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 520

Query: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 521 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 580

Query: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 581 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 640

Query: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 641 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 700

Query: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 701 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 760

Query: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 761 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 820

Query: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 821 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 880

Query: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 881 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 940

Query: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 941 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 978


>gi|14670354 general transcription factor II, i isoform 3 [Homo
           sapiens]
          Length = 977

 Score = 1942 bits (5030), Expect = 0.0
 Identities = 977/998 (97%), Positives = 977/998 (97%), Gaps = 21/998 (2%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPA        
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPA-------- 292

Query: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360
                        EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 293 -------------EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 339

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 340 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 399

Query: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 400 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 459

Query: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 460 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 519

Query: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 520 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 579

Query: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 580 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 639

Query: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 640 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 699

Query: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 700 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 759

Query: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 760 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 819

Query: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 820 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 879

Query: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 880 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 939

Query: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 940 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 977


>gi|169881252 general transcription factor II, i isoform 4 [Homo
           sapiens]
          Length = 957

 Score = 1890 bits (4895), Expect = 0.0
 Identities = 957/998 (95%), Positives = 957/998 (95%), Gaps = 41/998 (4%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           EESEDPDYYQYNIQ                    GSHHSSEGNEGTEMEVPA        
Sbjct: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPA-------- 272

Query: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360
                        EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 273 -------------EDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 319

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379

Query: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480
           RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 380 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 439

Query: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540
           ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 440 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 499

Query: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600
           PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 500 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 559

Query: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660
           ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 560 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 619

Query: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720
           INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 620 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 679

Query: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780
           FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 680 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 739

Query: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840
           RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 740 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 799

Query: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900
           VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 800 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 859

Query: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960
           PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 860 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 919

Query: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998
           GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 920 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 957


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score =  461 bits (1185), Expect = e-129
 Identities = 265/468 (56%), Positives = 313/468 (66%), Gaps = 45/468 (9%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           +ESEDP+YYQYN                    +QGSH SS  NE  EME+P EDST  VP
Sbjct: 236 KESEDPNYYQYN--------------------MQGSHPSSTSNEVIEMELPMEDSTPLVP 275

Query: 301 S-ETSEDPEVEVTIEDDDYSPPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWN 355
           S E +EDPE EV IE +  S       A      + Q  VP+       K R  + EK  
Sbjct: 276 SEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK-- 328

Query: 356 ARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYG 415
             I  LR+QV +LF RK+ +AI    PV +PY     +   + ++G+P G+ F+ P    
Sbjct: 329 --IKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLE 386

Query: 416 IPRLERILLAKERIRFVIKKH----ELLNSTREDLQLDKPASGVKEEW 459
           I  + RIL A E I+F + +     EL N  +   ++D+     +E+W
Sbjct: 387 ISSMRRILEAAEFIKFTVIRPLPGLELSNVGKR--KIDQEGRVFQEKW 432



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 830 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 889
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353

Query: 890 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 949
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413

Query: 950 NNQLVDQSESEGPVIQESAE 969
           +N    + + EG V QE  E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 421 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 475
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 476 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 522
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283

Query: 523 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 581
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342

Query: 582 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 641
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402

Query: 642 VVKKP 646
            V +P
Sbjct: 403 TVIRP 407



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)

Query: 571 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 630
           LRK VE+ F   + +ALG T  V VPY     +   + V+GLPEG+ F+ P  + +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 631 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 664
            I+     I F++ +P L                  ++S  P      IN K        
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224

Query: 665 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 697
                 A+   K    P              ++++V E+E+ +E           N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284

Query: 698 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 740
            + V+    TN S+                 VP   + R  S E    KI  L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339

Query: 741 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 800
           F+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL     
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399

Query: 801 IKFIIKKP 808
           IKF + +P
Sbjct: 400 IKFTVIRP 407



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 868 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 927
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 928 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 974
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 975 VPATEEIKETDGSSQIKQEPDPTW 998
           + A       +  S  K+  DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score =  461 bits (1185), Expect = e-129
 Identities = 265/468 (56%), Positives = 313/468 (66%), Gaps = 45/468 (9%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115

Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175

Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235

Query: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
           +ESEDP+YYQYN                    +QGSH SS  NE  EME+P EDST  VP
Sbjct: 236 KESEDPNYYQYN--------------------MQGSHPSSTSNEVIEMELPMEDSTPLVP 275

Query: 301 S-ETSEDPEVEVTIEDDDYSPPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWN 355
           S E +EDPE EV IE +  S       A      + Q  VP+       K R  + EK  
Sbjct: 276 SEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK-- 328

Query: 356 ARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYG 415
             I  LR+QV +LF RK+ +AI    PV +PY     +   + ++G+P G+ F+ P    
Sbjct: 329 --IKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLE 386

Query: 416 IPRLERILLAKERIRFVIKKH----ELLNSTREDLQLDKPASGVKEEW 459
           I  + RIL A E I+F + +     EL N  +   ++D+     +E+W
Sbjct: 387 ISSMRRILEAAEFIKFTVIRPLPGLELSNVGKR--KIDQEGRVFQEKW 432



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 830 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 889
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353

Query: 890 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 949
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413

Query: 950 NNQLVDQSESEGPVIQESAE 969
           +N    + + EG V QE  E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 421 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 475
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 476 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 522
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283

Query: 523 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 581
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342

Query: 582 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 641
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402

Query: 642 VVKKP 646
            V +P
Sbjct: 403 TVIRP 407



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)

Query: 571 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 630
           LRK VE+ F   + +ALG T  V VPY     +   + V+GLPEG+ F+ P  + +  L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 631 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 664
            I+     I F++ +P L                  ++S  P      IN K        
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224

Query: 665 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 697
                 A+   K    P              ++++V E+E+ +E           N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284

Query: 698 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 740
            + V+    TN S+                 VP   + R  S E    KI  L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339

Query: 741 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 800
           F+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL     
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399

Query: 801 IKFIIKKP 808
           IKF + +P
Sbjct: 400 IKFTVIRP 407



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 868 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 927
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166

Query: 928 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 974
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226

Query: 975 VPATEEIKETDGSSQIKQEPDPTW 998
           + A       +  S  K+  DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243


>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 959

 Score =  380 bits (975), Expect = e-105
 Identities = 302/992 (30%), Positives = 470/992 (47%), Gaps = 174/992 (17%)

Query: 22  VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
           ++T L+SAL+SMC  L+K  AEVAC+AV++   FVVGTE+GR F+N RK+ Q DF+++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
               K  E    K   +         R S++   ++  LRK VE+ F   Y +ALG+++V
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F +KRP  +   
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206

Query: 194 HVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNI 253
             GGR      D   L                E +G+SL      + + S D   +    
Sbjct: 207 --GGR------DSKAL---------------VELNGVSL------IPKGSRDCGLHGQAP 237

Query: 254 QAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVE 310
           +  P +         ++  L  +   +      + E P   S    PS+   +   PE +
Sbjct: 238 KVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAP---SCPLAPSDLGLSRPMPEPK 294

Query: 311 VTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------L 361
            T   D      ++P     P  P+ +  +A KR    +     EKW+A I +      L
Sbjct: 295 ATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTL 351

Query: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
           R+ V+ LF  +YA+A+     V +PY       E + + G+P+ IPF+RP TYG+P+L+R
Sbjct: 352 RECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKR 411

Query: 422 ILLAKERIRFVIKK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLF 474
           IL  +  I F+IK+   E +   N   +D    +PAS  ++     +R T L    +   
Sbjct: 412 ILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARS 471

Query: 475 CK-KFAEALG-STEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---S 517
            K   +E  G  T  +    +  +  P DL +            E + +++P   P   S
Sbjct: 472 DKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDS 531

Query: 518 WYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEE 577
            YG+                    E+LT             PV++     I  LRKQVE 
Sbjct: 532 GYGM--------------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVEL 571

Query: 578 IFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSN 637
           +FN ++A+A+G++E VKVPY  F  +PE L+V GLPEGI  R P  FGI +L +I+  SN
Sbjct: 572 LFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASN 631

Query: 638 KIKFVVKKPELVISYL-PPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNP 696
            I+FV+K+PEL+   +  P M S+    +L        P  +S  P ++ ++        
Sbjct: 632 SIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL-------- 683

Query: 697 QTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQ 753
                             K +G + +++A  ++I     L+++V++LFN+K GEALG+K 
Sbjct: 684 ------------------KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKY 725

Query: 754 AVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET 813
            V+VP+   +S P    +EGLP G+PFR+P TFG   LE+IL    KIKF + +P     
Sbjct: 726 PVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----- 780

Query: 814 AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVN 873
                                             Q  IP  D +  +++ +   LREQV 
Sbjct: 781 ---------------------------------FQGLIPKPDEDDANRLGEKVILREQVK 807

Query: 874 DLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSA 933
           +LF+ K+GEA+G+  PV VPY+ I  +P  V V G+P  + F+ P+  +I  + +IL + 
Sbjct: 808 ELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAR 867

Query: 934 EFIKFTVI---RPFPGLVINNQLVDQSESEGP 962
           E ++  +I   +PF   + N+  V   +S  P
Sbjct: 868 EHVRMVIINQLQPF-AEICNDAKVPAKDSSIP 898



 Score =  262 bits (670), Expect = 1e-69
 Identities = 205/635 (32%), Positives = 297/635 (46%), Gaps = 94/635 (14%)

Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
           +I TLR+ V+  F   Y +ALG   +VPVPY K+  D  AV + G+P+ + FK P  Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406

Query: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
             LK ILE +  I FIIKR F E  +   G     D  +  L P            P ED
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452

Query: 228 SGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTE 287
           +   +  A V     +   D    +   GP  + ++   +P+           E  +   
Sbjct: 453 TSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIK---------IEPEDLDI 503

Query: 288 MEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANE-LPQPPVPEPANAGKRKV 346
           ++V   D     PS TSE    E+T     + P        E L    + E A   +R V
Sbjct: 504 IQVTVPD-----PSPTSE----EMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPV 554

Query: 347 REFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGI 406
            + + +     I  LRKQVE LF  +YA+AI    PV +PY  F  H E+L+V GLPEGI
Sbjct: 555 EDSHGDV----IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGI 610

Query: 407 PFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NSTREDLQLDKPA--- 452
             RRP+ +GI +L +IL A   I+FVIK+ ELL             T   L    PA   
Sbjct: 611 SLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPP 670

Query: 453 ---------------SGVKEEWYARITK------LRKMVDQLFCKKFAEALGSTEAKAVP 491
                           G +E + AR+++      LR+ V  LF KK+ EALG      VP
Sbjct: 671 ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVP 730

Query: 492 YQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEV 551
           Y++ +++P  + +EGLP  IPFR P  +G   LE+I+ V ++IKF + RP          
Sbjct: 731 YKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP---------- 780

Query: 552 TQPRTNTPVKEDWNVRITK--LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYV 609
            Q     P ++D N    K  LR+QV+E+FN K+ +ALGL   V VPY +   +P+ + V
Sbjct: 781 FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEV 840

Query: 610 EGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA----SKINTKA 665
            GLP+ IPFR+P  + I RLE+I++    ++ V      +I+ L P       +K+  K 
Sbjct: 841 TGLPDDIPFRNPNTYDIHRLEKILKAREHVRMV------IINQLQPFAEICNDAKVPAKD 894

Query: 666 LQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSA 700
              PKR R   S         +    +++NP + A
Sbjct: 895 SSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVA 929



 Score =  143 bits (360), Expect = 9e-34
 Identities = 118/426 (27%), Positives = 192/426 (45%), Gaps = 120/426 (28%)

Query: 463 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 522
           I  LRK V+ LF  ++A+A+G +E   VPY KF  HP +L+V GLPE I  R P+ +GI 
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621

Query: 523 RLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP----------------------- 559
           +L KI++  N I+FVIKRPELLT    E       T                        
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDE 681

Query: 560 ------VKEDWNVRITK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFL 607
                  +E+++ R+++      LR+QV+++FN K+       EA+ + Y          
Sbjct: 682 SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYG------EALGIKY---------- 725

Query: 608 YVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQ 667
                P  +P++           RI      +         +I  LPPG+  +       
Sbjct: 726 -----PVQVPYK-----------RIKSNPGSV---------IIEGLPPGIPFR------- 753

Query: 668 SPKRPRSPGSNSK------VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721
              +P + GS +         +I+ TV       P    +  P + + + +  K      
Sbjct: 754 ---KPCTFGSQNLERILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK------ 799

Query: 722 SFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFR 781
                      L+++V+ LFNEK GEALGL + V VP+ L    P+   V GLP+ +PFR
Sbjct: 800 ---------VILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFR 850

Query: 782 RPSTFGIPRLEKILRNKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPN 833
            P+T+ I RLEKIL+ +  ++  II + + F       +   K+S+  K   ++++   +
Sbjct: 851 NPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNS 910

Query: 834 VNTTAS 839
           V++++S
Sbjct: 911 VSSSSS 916



 Score =  102 bits (255), Expect = 1e-21
 Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)

Query: 571 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 630
           LRK VEE+F++ +++ALG    V +PY      P  L V+GLPEG+ FR P  +    L 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 631 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 690
            I+  S++I+F +K+P L           ++N  +L  PK  R  G + + P++      
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239

Query: 691 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 750
           P  + P       PT T+ S   F      +S    N  I +LKQ+  +         LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285

Query: 751 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 809
           L + +  P A   +  +DF           ++P+  G P ++ +  +K  +  I+  K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336

Query: 810 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 869
            ++  IKE+                       ED+N                      LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352

Query: 870 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 929
           E V  LF+ ++ EA+G+   V VPYRKI  +P  V + G+P  + FK P    +  ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412

Query: 930 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 975
           L+    I F + R F   +       +     E   P    SAE S+  V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462


>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score =  374 bits (960), Expect = e-103
 Identities = 299/991 (30%), Positives = 467/991 (47%), Gaps = 187/991 (18%)

Query: 22  VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
           ++T L+SAL+SMC  L+K  AEVAC+AV++   FVVGTE+GR F+N RK+ Q DF+++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
               K  E    K   +         R S++   ++  LRK VE+ F   Y +ALG+++V
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F +KRP  +   
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206

Query: 194 HVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNI 253
             GGR      D   L                E +G+SL      + + S D   +    
Sbjct: 207 --GGR------DSKAL---------------VELNGVSL------IPKGSRDCGLHGQAP 237

Query: 254 QAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVE 310
           +  P +         ++  L  +   +      + E P   S    PS+   +   PE +
Sbjct: 238 KVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAP---SCPLAPSDLGLSRPMPEPK 294

Query: 311 VTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------L 361
            T   D      ++P     P  P+ +  +A KR    +     EKW+A I +      L
Sbjct: 295 ATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTL 351

Query: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
           R+ V+ LF  +YA+A+     V +PY       E + + G+P+ IPF+RP TYG+P+L+R
Sbjct: 352 RECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKR 411

Query: 422 ILLAKERIRFVIKK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLF 474
           IL  +  I F+IK+   E +   N   +D    +PAS  ++     +R T L    +   
Sbjct: 412 ILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARS 471

Query: 475 CK-KFAEALG-STEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---S 517
            K   +E  G  T  +    +  +  P DL +            E + +++P   P   S
Sbjct: 472 DKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDS 531

Query: 518 WYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEE 577
            YG+                    E+LT             PV++     I  LRKQVE 
Sbjct: 532 GYGM--------------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVEL 571

Query: 578 IFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSN 637
           +FN ++A+A+G++E VKVPY  F  +PE L+V GLPEGI  R P  FGI +L +I+  SN
Sbjct: 572 LFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASN 631

Query: 638 KIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQ 697
            I+FV+K+PEL        +   +    + S +R      +S  P ++ ++         
Sbjct: 632 SIQFVIKRPEL--------LTEGVKEPIVDSQER------DSGDPLVDESL--------- 668

Query: 698 TSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQA 754
                            K +G + +++A  ++I     L+++V++LFN+K GEALG+K  
Sbjct: 669 -----------------KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYP 711

Query: 755 VKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETA 814
           V+VP+   +S P    +EGLP G+PFR+P TFG   LE+IL    KIKF + +P      
Sbjct: 712 VQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP------ 765

Query: 815 IKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVND 874
                                            Q  IP  D +  +++ +   LREQV +
Sbjct: 766 --------------------------------FQGLIPKPDEDDANRLGEKVILREQVKE 793

Query: 875 LFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAE 934
           LF+ K+GEA+G+  PV VPY+ I  +P  V V G+P  + F+ P+  +I  + +IL + E
Sbjct: 794 LFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARE 853

Query: 935 FIKFTVI---RPFPGLVINNQLVDQSESEGP 962
            ++  +I   +PF   + N+  V   +S  P
Sbjct: 854 HVRMVIINQLQPF-AEICNDAKVPAKDSSIP 883



 Score =  265 bits (677), Expect = 2e-70
 Identities = 202/620 (32%), Positives = 297/620 (47%), Gaps = 79/620 (12%)

Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
           +I TLR+ V+  F   Y +ALG   +VPVPY K+  D  AV + G+P+ + FK P  Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406

Query: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
             LK ILE +  I FIIKR F E  +   G     D  +  L P            P ED
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452

Query: 228 SGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTE 287
           +   +  A V     +   D    +   GP  + ++   +P+           E  +   
Sbjct: 453 TSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIK---------IEPEDLDI 503

Query: 288 MEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANE-LPQPPVPEPANAGKRKV 346
           ++V   D     PS TSE    E+T     + P        E L    + E A   +R V
Sbjct: 504 IQVTVPD-----PSPTSE----EMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPV 554

Query: 347 REFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGI 406
            + + +     I  LRKQVE LF  +YA+AI    PV +PY  F  H E+L+V GLPEGI
Sbjct: 555 EDSHGDV----IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGI 610

Query: 407 PFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDK--------------PA 452
             RRP+ +GI +L +IL A   I+FVIK+ ELL    ++  +D                 
Sbjct: 611 SLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKR 670

Query: 453 SGVKEEWYARITK------LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEG 506
            G +E + AR+++      LR+ V  LF KK+ EALG      VPY++ +++P  + +EG
Sbjct: 671 QGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEG 730

Query: 507 LPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNV 566
           LP  IPFR P  +G   LE+I+ V ++IKF + RP           Q     P ++D N 
Sbjct: 731 LPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANR 780

Query: 567 RITK--LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWF 624
              K  LR+QV+E+FN K+ +ALGL   V VPY +   +P+ + V GLP+ IPFR+P  +
Sbjct: 781 LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY 840

Query: 625 GIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSK 680
            I RLE+I++    ++ V      +I+ L P       +K+  K    PKR R   S   
Sbjct: 841 DIHRLEKILKAREHVRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGN 894

Query: 681 VPEIEVTVEGPNNNNPQTSA 700
                 +    +++NP + A
Sbjct: 895 SVSSSSSSSSSSSSNPDSVA 914



 Score =  149 bits (375), Expect = 2e-35
 Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)

Query: 463 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 522
           I  LRK V+ LF  ++A+A+G +E   VPY KF  HP +L+V GLPE I  R P+ +GI 
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621

Query: 523 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 568
           +L KI++  N I+FVIKRPELLT    E              V +       +E+++ R+
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681

Query: 569 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 622
           ++      LR+QV+++FN K+       EA+ + Y               P  +P++   
Sbjct: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717

Query: 623 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 680
                   RI      +         +I  LPPG+  +          +P + GS +   
Sbjct: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750

Query: 681 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 736
                 +I+ TV       P    +  P + + + +  K                 L+++
Sbjct: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790

Query: 737 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 796
           V+ LFNEK GEALGL + V VP+ L    P+   V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850

Query: 797 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 839
            +  ++  II + + F       +   K+S+  K   ++++   +V++++S
Sbjct: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901



 Score =  102 bits (255), Expect = 1e-21
 Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)

Query: 571 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 630
           LRK VEE+F++ +++ALG    V +PY      P  L V+GLPEG+ FR P  +    L 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 631 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 690
            I+  S++I+F +K+P L           ++N  +L  PK  R  G + + P++      
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239

Query: 691 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 750
           P  + P       PT T+ S   F      +S    N  I +LKQ+  +         LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285

Query: 751 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 809
           L + +  P A   +  +DF           ++P+  G P ++ +  +K  +  I+  K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336

Query: 810 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 869
            ++  IKE+                       ED+N                      LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352

Query: 870 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 929
           E V  LF+ ++ EA+G+   V VPYRKI  +P  V + G+P  + FK P    +  ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412

Query: 930 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 975
           L+    I F + R F   +       +     E   P    SAE S+  V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462


>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
           sapiens]
          Length = 145

 Score =  159 bits (401), Expect = 2e-38
 Identities = 98/187 (52%), Positives = 111/187 (59%), Gaps = 43/187 (22%)

Query: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESM-CKELAKSKAEVACIAVYETDVFVVGT 59
           MAQV +STL +EDE+S ESRMVVTFLMSALES  C  +   K E  C  +Y   V+  G 
Sbjct: 1   MAQVLVSTLSIEDEDSYESRMVVTFLMSALESTDCFRVWILKQE--CTLIYHKKVYNPG- 57

Query: 60  ERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDY 119
                                        E  + +     N          T +KTVEDY
Sbjct: 58  -----------------------------ESDECRCCRNGN----------TRKKTVEDY 78

Query: 120 FCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAG 179
           FCFC  KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL+WILE  AG
Sbjct: 79  FCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAG 138

Query: 180 ISFIIKR 186
           ISFIIKR
Sbjct: 139 ISFIIKR 145



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 27/74 (36%), Positives = 39/74 (52%)

Query: 467 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 526
           +K V+  FC    +AL       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 527 IIQVGNRIKFVIKR 540
           I++    I F+IKR
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/74 (39%), Positives = 38/74 (51%)

Query: 734 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 793
           K+ VE+ F   C +AL     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 794 ILRNKAKIKFIIKK 807
           IL   A I FIIK+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 26/74 (35%), Positives = 38/74 (51%)

Query: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
           +K VE+ F     +A++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 422 ILLAKERIRFVIKK 435
           IL     I F+IK+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/74 (33%), Positives = 39/74 (52%)

Query: 572 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 631
           +K VE+ F     +AL     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 632 IVRGSNKIKFVVKK 645
           I+  +  I F++K+
Sbjct: 132 ILEYTAGISFIIKR 145



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 22/74 (29%), Positives = 39/74 (52%)

Query: 869 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 928
           ++ V D F     +A+     V VPY K+  +   ++V G+P GV+FK P   +++++  
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 929 ILDSAEFIKFTVIR 942
           IL+    I F + R
Sbjct: 132 ILEYTAGISFIIKR 145


>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 298

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 766 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 817
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 818 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 876
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 877 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 936
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 937 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 969
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 498 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 550
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 551 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 582
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 583 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 642
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 643 VKKP 646
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 393 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 441
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 442 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 477
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 478 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 537
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 538 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 591
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 603 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 661
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 662 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 722 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 778
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 779 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 838
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 839 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 884
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 318 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 374
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 375 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 434
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 435 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 482
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 899 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 943
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 766 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 817
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 818 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 876
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 877 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 936
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 937 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 969
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 498 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 550
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 551 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 582
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 583 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 642
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 643 VKKP 646
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 393 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 441
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 442 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 477
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 478 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 537
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 538 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 591
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 603 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 661
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 662 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 722 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 778
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 779 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 838
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 839 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 884
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 318 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 374
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 375 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 434
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 435 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 482
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 899 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 943
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score =  131 bits (330), Expect = 3e-30
 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)

Query: 766 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 817
           PE+ +V GLPEG+  RRP+ FGI +L KIL     I+F+IK+P++    +KE        
Sbjct: 3   PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62

Query: 818 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 876
            S+   SPP    + P    +   +   ++ +    ++ + RL +++ A  LREQV +LF
Sbjct: 63  ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118

Query: 877 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 936
           ++ +GEA+G+ +PV+VPY+ I  NPG ++++ +PPG+ F+ P      ++ RIL  A  I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176

Query: 937 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 969
            FTV RPF GL+      D +     ++QE  +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209



 Score =  111 bits (278), Expect = 3e-24
 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)

Query: 498 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 550
           HP +L+V GLPE I  R P+ +GI +L KI++  N I+FVIKRP+LLT    E       
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 551 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 582
                                 V +       +E+++ R+ +      LR+QV+E+FN  
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 583 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 642
           + +ALG+   V+VPY   +SNP  + +E LP GI FR P  FG   LERI+  +NKI F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 643 VKKP 646
           V +P
Sbjct: 180 VTRP 183



 Score =  107 bits (268), Expect = 4e-23
 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)

Query: 393 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 441
           H E+L+V GLPEGI  RRP+ +GI +L +IL A   I+FVIK+ +LL             
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 442 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 477
           T   L    PA                   G +E + AR+ +      LR+ V +LF K 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121

Query: 478 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 537
           + EALG      VPY+  +++P  + +E LP  I FR P  +G   LE+I+ + N+I F 
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179

Query: 538 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 591
           + RP           Q     P ++D N +    L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)

Query: 603 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 661
           +PE L+V GLPEGI  R P  FGI +L +I+  SN I+FV+K+P+L+   +  P + S+ 
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61

Query: 662 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721
              +L        P  +S+ P +  ++                          K +G + 
Sbjct: 62  TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95

Query: 722 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 778
           +++A   +I     L+++V+ LFN+  GEALG+K  V+VP+   +S P    +E LP G+
Sbjct: 96  NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155

Query: 779 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 838
            FR+P  FG   LE+IL    KI F + +P  F+  I++                     
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191

Query: 839 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 884
                         +DD  RL +V     L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)

Query: 318 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 374
           +SPP+  P+ +       P    + KR+  + N++    RI     LR+QV+ELF + Y 
Sbjct: 68  FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123

Query: 375 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 434
           +A+  K PV +PY   +S+   + +E LP GI FR+P  +G   LERIL    +I F + 
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181

Query: 435 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 482
           +    L+    ED   D    G           L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           TLR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166

Query: 171 KWILENKAGISFIIKRPF 188
           + IL     I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
           V GLPEG++ + P  + +A L  ILE    I F+IKRP L
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 14/45 (31%), Positives = 29/45 (64%)

Query: 899 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 943
           ++P  + V G+P G+S + P+   I+ + +IL+++  I+F + RP
Sbjct: 1   MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
           sapiens]
          Length = 304

 Score =  129 bits (324), Expect = 1e-29
 Identities = 62/75 (82%), Positives = 67/75 (89%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           T +KTVEDYFCFC  KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19  TRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78

Query: 171 KWILENKAGISFIIK 185
           +WILE  AGISFIIK
Sbjct: 79  EWILEYTAGISFIIK 93



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 734 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 793
           K+ VE+ F   C +AL     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 794 ILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSS 831
           IL   A I FIIK               ++PP ++N +
Sbjct: 81  ILEYTAGISFIIKS--------SGEPQGRTPPLRLNQA 110



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/73 (35%), Positives = 38/73 (52%)

Query: 467 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 526
           +K V+  FC    +AL       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 527 IIQVGNRIKFVIK 539
           I++    I F+IK
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 37/73 (50%)

Query: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
           +K VE+ F     +A++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 422 ILLAKERIRFVIK 434
           IL     I F+IK
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 25/73 (34%), Positives = 38/73 (52%)

Query: 572 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 631
           +K VE+ F     +AL     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 632 IVRGSNKIKFVVK 644
           I+  +  I F++K
Sbjct: 81  ILEYTAGISFIIK 93



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 21/72 (29%), Positives = 38/72 (52%)

Query: 869 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 928
           ++ V D F     +A+     V VPY K+  +   ++V G+P GV+FK P   +++++  
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 929 ILDSAEFIKFTV 940
           IL+    I F +
Sbjct: 81  ILEYTAGISFII 92


>gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial
           [Homo sapiens]
          Length = 94

 Score =  129 bits (323), Expect = 2e-29
 Identities = 62/76 (81%), Positives = 67/76 (88%)

Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
           T +KTVEDYFCFC  K L K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19  TRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78

Query: 171 KWILENKAGISFIIKR 186
           +WILE  AGISFIIKR
Sbjct: 79  EWILEYTAGISFIIKR 94



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 26/74 (35%), Positives = 38/74 (51%)

Query: 467 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 526
           +K V+  FC    + L       VPY+K     + L V+GLPE + F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 527 IIQVGNRIKFVIKR 540
           I++    I F+IKR
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 28/74 (37%), Positives = 37/74 (50%)

Query: 734 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 793
           K+ VE+ F   C + L     V VP+           V+GLPEGV F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 794 ILRNKAKIKFIIKK 807
           IL   A I FIIK+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/74 (33%), Positives = 37/74 (50%)

Query: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
           +K VE+ F     + ++    V +PY         L V+GLPEG+ F+ P  Y +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 422 ILLAKERIRFVIKK 435
           IL     I F+IK+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 24/74 (32%), Positives = 38/74 (51%)

Query: 572 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 631
           +K VE+ F     + L     V VPY     +   L V+GLPEG+ F+ P  + +  LE 
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 632 IVRGSNKIKFVVKK 645
           I+  +  I F++K+
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 890 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIR 942
           V VPY K+  +   ++V G+P GV+FK P   +++++  IL+    I F + R
Sbjct: 42  VPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94


>gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo
           sapiens]
          Length = 361

 Score =  113 bits (283), Expect = 8e-25
 Identities = 76/187 (40%), Positives = 94/187 (50%), Gaps = 40/187 (21%)

Query: 323 KRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGP 382
           ++ K NE PQPPVPEPANAG+RK+REFN EKWN RI DLRKQ EEL ERKY  +   K  
Sbjct: 214 RKTKTNEPPQPPVPEPANAGERKMREFNSEKWNHRIADLRKQTEELSERKYGMSKLEKSC 273

Query: 383 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNST 442
             +   ++   VE L++ G+P   P       G+P    IL            HEL+NST
Sbjct: 274 NLMFMGVYT--VELLFIMGVPWTSP-------GLPASHAILTC-------FSLHELMNST 317

Query: 443 REDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDL 502
            EDLQLDK          AR  K +  V                   +PY  F++H  D 
Sbjct: 318 GEDLQLDKSTLS------ARAVKAKGPV------------------MIPYPFFQSHVEDF 353

Query: 503 YVEGLPE 509
           Y E LP+
Sbjct: 354 YAEALPK 360



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 13/28 (46%), Positives = 18/28 (64%)

Query: 719 REFSFEAWNAKITDLKQKVENLFNEKCG 746
           REF+ E WN +I DL+++ E L   K G
Sbjct: 238 REFNSEKWNHRIADLRKQTEELSERKYG 265



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 13/29 (44%), Positives = 18/29 (62%)

Query: 748 ALGLKQAVKVPFALFESFPEDFYVEGLPE 776
           A+  K  V +P+  F+S  EDFY E LP+
Sbjct: 332 AVKAKGPVMIPYPFFQSHVEDFYAEALPK 360


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo
          sapiens]
          Length = 561

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/41 (70%), Positives = 32/41 (78%), Gaps = 7/41 (17%)

Query: 1  MAQVAMSTLP------VEDEESSESRMVVTFLMSALESMCK 35
          MAQVA+STLP      VEDEES ESRMVVTFL SAL+SM +
Sbjct: 1  MAQVAVSTLPIEDEESVEDEESLESRMVVTFL-SALDSMVR 40


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 133/606 (21%), Positives = 221/606 (36%), Gaps = 124/606 (20%)

Query: 287   EMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKV 346
             E E+P E+  + VP E    PE E  + +++  P  K       P+ PVP P    K+KV
Sbjct: 10144 EEEIPPEE--EEVPPEEEYVPEEEEFVPEEEVLPEVK-------PKVPVPAPVPEIKKKV 10194

Query: 347   REFNF------EKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVE 400
              E         E   A++ ++ K+VEE       + I  K    +P  + +   E+   E
Sbjct: 10195 TEKKVVIPKKEEAPPAKVPEVPKKVEE------KRIILPKEEEVLPVEVTEEPEEEPISE 10248

Query: 401   GLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWY 460
                E IP   PS   I  +E +  A  R+  VIKK      T    +++ P + V     
Sbjct: 10249 ---EEIPEEPPS---IEEVEEV--APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVS---- 10296

Query: 461   ARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRS----- 515
                            KK  E     E   VP QK EA P    V  +P+ +P +      
Sbjct: 10297 ---------------KKIPE-----EKVPVPVQKKEAPP--AKVPEVPKKVPEKKVLVPK 10334

Query: 516   ----PSWYGIPRLEKIIQVGNRIKFVIKRP---ELLTHSTTEVTQPRTNTPVKEDWN--- 565
                 P   G   LE+ + V  R + V+K     E++     E+ +      V+E +    
Sbjct: 10335 KEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGE 10394

Query: 566   -------VRITKLR-------KQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEG 611
                    +++ + R       ++V  +  +  A+ + + E  K P    E + + +  + 
Sbjct: 10395 FHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK 10454

Query: 612   LPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVK---KPELVISYLPPGMASKINTKALQS 668
              P  +  R      +P + + +    K++   +    P  V   LPP          +  
Sbjct: 10455 PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPP 10514

Query: 669   PKRPRSP------GSNSKVPEIEVTV------EGPNNNNPQTSAVRTPTQTNGSNVPFKP 716
              K+P +P           VPE +V V      E P    P+      P +     +P KP
Sbjct: 10515 AKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP 10574

Query: 717   RGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQ----AVKVPFALFESFPEDFYVE 772
                        +   ++ +  + +  EK   A   K+     VKVP A  E  PE   V 
Sbjct: 10575 ----------ESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVP 10623

Query: 773   GLPEGVPFRRPSTFGIPRLEKILRNKAKIKFII------KKPEMFETAIKESTSSKSPPR 826
               P   P   P+   +P + K+   + K+   I        PE+FE    E  + + PP 
Sbjct: 10624 VPPPKKPEVPPTK--VPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--PEEVALEEPPA 10679

Query: 827   KINSSP 832
             ++   P
Sbjct: 10680 EVVEEP 10685



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 18/165 (10%)

Query: 226  EDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEG 285
            E+ G+S+ +     +EE E+ +  +Y +   P E    ++   +SK ++     +E  E 
Sbjct: 9500 EEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVE-----AEPAEV 9554

Query: 286  TEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP----PSKRPKANELPQPPVPE---- 337
            TE +         +P++  E P  +V        P    P+  PK  ++P P VPE    
Sbjct: 9555 TERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKK 9614

Query: 338  --PANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 380
              P      KV +   E   A++T+   Q+ +  E K   A+  K
Sbjct: 9615 PVPEKKVPPKVIKME-EPLPAKVTERHMQITQ--EEKVLVAVTKK 9656



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 61/235 (25%), Positives = 92/235 (39%), Gaps = 44/235 (18%)

Query: 134   VPVPYEKMLRDQSA-VVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPK 192
             V VP +K + ++ A  VV   PE    K PE       K ++  K       K P + PK
Sbjct: 10693 VTVPPKKPVPEKKAPAVVAKKPELPPVKVPE-----VPKEVVPEK-------KVPLVVPK 10740

Query: 193   KHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTE-----DSGISLEMAAVTVKE--ESED 245
             K       V +  + ++       P K +  P +        +  E  AV V E  ES  
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP 10800

Query: 246   PDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSE 305
             P+ Y+   +  P E    +E++P+              E  E EVP       VP E  +
Sbjct: 10801 PEVYEEPEEIAPEEEIAPEEEKPVPVA-----------EEEEPEVPPPA----VPEEPKK 10845

Query: 306   D-PEVEVTIEDDDYSPPSKRPKANEL-------PQPPVPEPANAGKRKVREFNFE 352
               PE +V +     +PP K P+  ++       P+PP P PA   K  V+E  F+
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPA-PPKEDVKEKIFQ 10899



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 105/497 (21%), Positives = 184/497 (37%), Gaps = 117/497 (23%)

Query: 217   PIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGS 276
             P+KV   P +   +  E   V V ++ E P      +   P      +EK P+  P    
Sbjct: 9947  PVKVPEVPRKP--VPEEKKPVPVPKKKEAPPAKVPEVPKKP------EEKVPVLIP---- 9994

Query: 277   HHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVP 336
                       + E P       VP +   + +V V +     +PP+K P   E+P+ PVP
Sbjct: 9995  ----------KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVP---EVPKKPVP 10041

Query: 337   E---PANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSH 393
             E   P  A K+       E   A++ ++ K++            + K P  +P       
Sbjct: 10042 EKKVPVPAPKK------VEAPPAKVPEVPKKL----------IPEEKKPTPVPKK----- 10080

Query: 394   VEDLYVEGLPEGIPFRR---PSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDK 450
                  VE  P  +P +R   P    +P+ E +L  +E    ++ + E+L    E L  ++
Sbjct: 10081 -----VEAPPPKVPKKREPVPVPVALPQEEEVLFEEE----IVPEEEVLPEEEEVLPEEE 10131

Query: 451   PASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPEN 510
                  +EE                           E + +P ++ E  P + YV   PE 
Sbjct: 10132 EVLPEEEEVL------------------------PEEEEIPPEEEEVPPEEEYV---PEE 10164

Query: 511   IPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDW-NVRIT 569
               F       +P  E + +V  ++      PE+      +VT+ +   P KE+    ++ 
Sbjct: 10165 EEF-------VPEEEVLPEVKPKVPVPAPVPEI----KKKVTEKKVVIPKKEEAPPAKVP 10213

Query: 570   KLRKQVEEIFNLKFAQALGLTEAVKVPYPVFES-NPEFLYVEGLPEGIP-FRSPTWFGIP 627
             ++ K+VEE       + +   E   +P  V E    E +  E +PE  P          P
Sbjct: 10214 EVPKKVEE------KRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPP 10267

Query: 628   RLERIVRGSNKIKFVVKKPELV---ISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEI 684
             R+  +++     K V + P  V   +   P  ++ KI  + +  P + +     +KVPE+
Sbjct: 10268 RVPEVIK-----KAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQ-KKEAPPAKVPEV 10321

Query: 685   EVTVEGPNNNNPQTSAV 701
                V       P+  AV
Sbjct: 10322 PKKVPEKKVLVPKKEAV 10338



 Score = 30.8 bits (68), Expect = 6.6
 Identities = 57/213 (26%), Positives = 78/213 (36%), Gaps = 24/213 (11%)

Query: 137   PYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK--H 194
             P E  L +  A VV+  PE  A   P    +   K + E KA  + + K+P L P K   
Sbjct: 10669 PEEVALEEPPAEVVEE-PEPAA---PPQVTVPPKKPVPEKKAP-AVVAKKPELPPVKVPE 10723

Query: 195   VGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQ 254
             V   V+       ++       P KV   P E     +    V V ++ E P      + 
Sbjct: 10724 VPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE----VVPEKKVAVPKKPEVPPAKVPEVP 10779

Query: 255   AGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAED----STQHVPSETSEDPEV- 309
               P     ++EK  +  P +      E  E  E   P E+      + VP    E+PEV 
Sbjct: 10780 KKPV----LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP 10835

Query: 310   --EVTIEDDDYSPPSKRP--KANELPQPPVPEP 338
                V  E     P  K P  K  E P P  PEP
Sbjct: 10836 PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 8/141 (5%)

Query: 200 MVTDADRSILSPG-GSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPS 258
           +  +A  +  SPG G  G  + + EP   S    +   VT  E S  PD      Q+ P 
Sbjct: 4   VAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASV-PDGETDGQQSAPQ 62

Query: 259 ETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQ-HVPSETSEDPEVEVTIEDDD 317
                 ++ PL  P       +   E    E+ AE+     V    +  P+    +    
Sbjct: 63  A-----DEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSP 117

Query: 318 YSPPSKRPKANELPQPPVPEP 338
            SPP + P   E  +PP+P+P
Sbjct: 118 ASPPEQPPAPEEREEPPLPQP 138


>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
          Length = 560

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 8/141 (5%)

Query: 200 MVTDADRSILSPG-GSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPS 258
           +  +A  +  SPG G  G  + + EP   S    +   VT  E S  PD      Q+ P 
Sbjct: 4   VAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASV-PDGETDGQQSAPQ 62

Query: 259 ETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQ-HVPSETSEDPEVEVTIEDDD 317
                 ++ PL  P       +   E    E+ AE+     V    +  P+    +    
Sbjct: 63  A-----DEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSP 117

Query: 318 YSPPSKRPKANELPQPPVPEP 338
            SPP + P   E  +PP+P+P
Sbjct: 118 ASPPEQPPAPEEREEPPLPQP 138


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 38.5 bits (88), Expect = 0.032
 Identities = 27/138 (19%), Positives = 55/138 (39%), Gaps = 10/138 (7%)

Query: 223  EPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEG 282
            E  E+   S E+ A +  + S  P+          +ET + + ++   KP          
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPE----------TETKEPEVEEEEEKPRVSEEQRQSE 1287

Query: 283  NEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAG 342
             E  E+E P  +  +   +ET+++ + +   EDD +   +K+ +  E P     +     
Sbjct: 1288 EEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV 1347

Query: 343  KRKVREFNFEKWNARITD 360
            +    + N +K   +I D
Sbjct: 1348 QESFLDANMQKSREKIKD 1365



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 22/106 (20%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 237  VTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDST 296
            V++ +    P   +      P E   + E++   + +Q    + E  EG E +  + +  
Sbjct: 1193 VSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAE--AEEAEEGEEEDAASSEVP 1250

Query: 297  QHVPSETSEDPEVEV---TIEDDDYSP-PSKRPKANELPQPPVPEP 338
               P+++S  PE E     +E+++  P  S+  + +E  Q  + EP
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 38.5 bits (88), Expect = 0.032
 Identities = 27/138 (19%), Positives = 55/138 (39%), Gaps = 10/138 (7%)

Query: 223  EPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEG 282
            E  E+   S E+ A +  + S  P+          +ET + + ++   KP          
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPE----------TETKEPEVEEEEEKPRVSEEQRQSE 1287

Query: 283  NEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAG 342
             E  E+E P  +  +   +ET+++ + +   EDD +   +K+ +  E P     +     
Sbjct: 1288 EEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV 1347

Query: 343  KRKVREFNFEKWNARITD 360
            +    + N +K   +I D
Sbjct: 1348 QESFLDANMQKSREKIKD 1365



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 22/106 (20%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 237  VTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDST 296
            V++ +    P   +      P E   + E++   + +Q    + E  EG E +  + +  
Sbjct: 1193 VSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAE--AEEAEEGEEEDAASSEVP 1250

Query: 297  QHVPSETSEDPEVEV---TIEDDDYSP-PSKRPKANELPQPPVPEP 338
               P+++S  PE E     +E+++  P  S+  + +E  Q  + EP
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 38.5 bits (88), Expect = 0.032
 Identities = 27/138 (19%), Positives = 55/138 (39%), Gaps = 10/138 (7%)

Query: 223  EPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEG 282
            E  E+   S E+ A +  + S  P+          +ET + + ++   KP          
Sbjct: 1238 EGEEEDAASSEVPAASPADSSNSPE----------TETKEPEVEEEEEKPRVSEEQRQSE 1287

Query: 283  NEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAG 342
             E  E+E P  +  +   +ET+++ + +   EDD +   +K+ +  E P     +     
Sbjct: 1288 EEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV 1347

Query: 343  KRKVREFNFEKWNARITD 360
            +    + N +K   +I D
Sbjct: 1348 QESFLDANMQKSREKIKD 1365



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 22/106 (20%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 237  VTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDST 296
            V++ +    P   +      P E   + E++   + +Q    + E  EG E +  + +  
Sbjct: 1193 VSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAE--AEEAEEGEEEDAASSEVP 1250

Query: 297  QHVPSETSEDPEVEV---TIEDDDYSP-PSKRPKANELPQPPVPEP 338
               P+++S  PE E     +E+++  P  S+  + +E  Q  + EP
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEP 1296


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 38.5 bits (88), Expect = 0.032
 Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 12/78 (15%)

Query: 262 DVDEKQPLSKP---LQGSHHSSEGNEGTEMEVPAEDSTQHVPSETS--EDPEVEVTIEDD 316
           D D+  P S P    + SHH+SEG + +      +DS+ H  SE+S   D E E +  D 
Sbjct: 397 DCDKTMPRSTPGSNSEPSHHNSEGADNSR-----DDSSSHSGSESSSGSDSESESSSSDS 451

Query: 317 DYSPPSKRPKANELPQPP 334
           + + PS+   A+  P+PP
Sbjct: 452 EANEPSQ--SASPEPEPP 467


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 38.1 bits (87), Expect = 0.042
 Identities = 51/187 (27%), Positives = 76/187 (40%), Gaps = 18/187 (9%)

Query: 206 RSILSPGGSCGPIKVKTEPTEDSGISLEMAA-----VTVKEESEDPDYYQYNIQAGPSET 260
           R  LSPG S       TE T+D     E+A      + V E  E       ++QA     
Sbjct: 653 RKSLSPGVSRDSSTSYTE-TKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQ 711

Query: 261 DDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEV---TIEDDD 317
            +  EK  +++ LQ    S +  E  E E PA    Q   ++TS  PE E    T+E+ +
Sbjct: 712 PESAEKH-VTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKE 770

Query: 318 ---YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYA 374
                    RP+ N++P+PP+P           E + E    + + L K     F+RK +
Sbjct: 771 EVTMDTSENRPE-NDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKS----FKRKIS 825

Query: 375 QAIKAKG 381
                KG
Sbjct: 826 VVSATKG 832


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 37.0 bits (84), Expect = 0.093
 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 43/184 (23%)

Query: 203 DADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDD 262
           DA+ S   P G   P++ +  P EDS    +    +V++ SED             E D+
Sbjct: 471 DANSSDCEPEG---PVEAEEPPQEDSSSQSD----SVEDRSED-------------EEDE 510

Query: 263 VDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPS 322
             E++  S        +SE +E  E E  A+  +Q    E  +D  VE  +  D+     
Sbjct: 511 HSEEEETS-----GSSASEESESEESE-DAQSQSQADEEEEDDDFGVEYLLARDE----- 559

Query: 323 KRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQA-IKAKG 381
           ++ +A+    PP P P   G +K            ITD+    E L  + Y  A  + K 
Sbjct: 560 EQSEADAGSGPPTPGPTTLGPKK-----------EITDIAAAAESLQPKGYTLATTQVKT 608

Query: 382 PVTI 385
           P+ +
Sbjct: 609 PIPL 612


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
            sapiens]
          Length = 2997

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 13/136 (9%)

Query: 256  GPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIED 315
            G  E ++ D     SK    +  SS  NE   +EV A+  ++ +  + SE+ E E  +ED
Sbjct: 2189 GKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDE-EEKLED 2247

Query: 316  DDYSPPSKRPKANELPQ-PPVPEPANAGKRKVRE-----FNFEKWNARITDLRKQVEELF 369
            DD S  S +P+A  + +     E +NA     R+     F  E  +  +  L      L 
Sbjct: 2248 DDKSEESSQPEAGAVSRGKNFDEESNASMSTARDETRDGFYMEDGDPSVAQL------LH 2301

Query: 370  ERKYAQAIKAKGPVTI 385
            ER +A +   K  V I
Sbjct: 2302 ERTFAFSFWPKDRVMI 2317


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 36.2 bits (82), Expect = 0.16
 Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 17/138 (12%)

Query: 221 KTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSS 280
           KT      G S  +       +SED D  Q   +  PS +      Q L +P+  +H SS
Sbjct: 410 KTHSNSQQGTSSMLEDDLQLSDSEDSDSEQ-TPEKPPSSSAPPSAPQSLPEPVASAHSSS 468

Query: 281 EGNEGT---------EMEVPAEDSTQHVPSET-SEDPEVEVT--IEDDDY----SPPSKR 324
             +E T         E E  + DS ++ P ET + +PE   T   + D++    S P+  
Sbjct: 469 AESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAP 528

Query: 325 PKANELPQPPVPEPANAG 342
           P+     +PP   P + G
Sbjct: 529 PEGPRSTEPPRRHPESKG 546



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 7/92 (7%)

Query: 256 GPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEV---EVT 312
           GP  T+    + P SK   GS  S+   E +E + P   S+   P    E P        
Sbjct: 531 GPRSTEP-PRRHPESK---GSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQ 586

Query: 313 IEDDDYSPPSKRPKANELPQPPVPEPANAGKR 344
                  PP ++    + P+ PV   A AG R
Sbjct: 587 KSPAQQEPPQRQTVGTKQPKKPVKASARAGSR 618


>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
          Length = 939

 Score = 36.2 bits (82), Expect = 0.16
 Identities = 24/105 (22%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 627 PRLERIVRGSNKIKFVVKKPELV------ISYLPPGMASKINTKALQS-PKRPRSPGSNS 679
           P  E+  + +NK KF +++PE++      + + P  +++   +   +S P+R  S G+NS
Sbjct: 460 PTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNS 519

Query: 680 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFE 724
               +    + P  + P++++++    T  S +  K R     FE
Sbjct: 520 YATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFE 564


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 35.4 bits (80), Expect = 0.27
 Identities = 33/157 (21%), Positives = 67/157 (42%), Gaps = 13/157 (8%)

Query: 221  KTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSK-----PLQG 275
            KT+P E   +          E+SED D+ +  +    SE++  DE++P ++      L+ 
Sbjct: 1319 KTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE--DEQRPRTRSAKKAELEE 1376

Query: 276  SHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPV 335
            +  S +  +        EDS+    S + E+ E +   E+++     +    N+  + P 
Sbjct: 1377 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP- 1435

Query: 336  PEPANAGKRKVRE-FNFEKWNARITDLRKQVEELFER 371
                  G++K+R+    +K      +  K+ EE  +R
Sbjct: 1436 ----GKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1468


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 35.4 bits (80), Expect = 0.27
 Identities = 33/157 (21%), Positives = 67/157 (42%), Gaps = 13/157 (8%)

Query: 221  KTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSK-----PLQG 275
            KT+P E   +          E+SED D+ +  +    SE++  DE++P ++      L+ 
Sbjct: 1357 KTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE--DEQRPRTRSAKKAELEE 1414

Query: 276  SHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPV 335
            +  S +  +        EDS+    S + E+ E +   E+++     +    N+  + P 
Sbjct: 1415 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP- 1473

Query: 336  PEPANAGKRKVRE-FNFEKWNARITDLRKQVEELFER 371
                  G++K+R+    +K      +  K+ EE  +R
Sbjct: 1474 ----GKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1506


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,600,592
Number of Sequences: 37866
Number of extensions: 2034438
Number of successful extensions: 7226
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 6678
Number of HSP's gapped (non-prelim): 444
length of query: 998
length of database: 18,247,518
effective HSP length: 112
effective length of query: 886
effective length of database: 14,006,526
effective search space: 12409782036
effective search space used: 12409782036
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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