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Search of human proteins with 14165435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
(463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 953 0.0
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 943 0.0
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 943 0.0
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 155 7e-38
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 155 7e-38
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 155 1e-37
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 155 1e-37
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 139 7e-33
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 106 4e-23
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 106 4e-23
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 106 4e-23
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 106 5e-23
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 100 5e-21
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 100 5e-21
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 94 3e-19
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 70 3e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 70 3e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 70 4e-12
gi|17402900 far upstream element-binding protein [Homo sapiens] 67 4e-11
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 64 4e-10
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 63 5e-10
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 59 9e-09
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 59 1e-08
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 58 2e-08
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 56 6e-08
gi|5730027 KH domain containing, RNA binding, signal transductio... 55 1e-07
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 54 2e-07
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 54 4e-07
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 52 1e-06
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 52 1e-06
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 953 bits (2464), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
Query: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF 463
IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF 463
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 943 bits (2438), Expect = 0.0
Identities = 458/459 (99%), Positives = 459/459 (100%)
Query: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
Query: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYS 459
IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQY+
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYA 459
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 943 bits (2438), Expect = 0.0
Identities = 458/459 (99%), Positives = 459/459 (100%)
Query: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK
Sbjct: 1 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGK 60
Query: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT
Sbjct: 61 GGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTAT 120
Query: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL
Sbjct: 121 SQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKL 180
Query: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT
Sbjct: 181 FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFT 240
Query: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG
Sbjct: 241 MMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG 300
Query: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA
Sbjct: 301 GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMA 360
Query: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS
Sbjct: 361 YEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYS 459
IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQY+
Sbjct: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYA 459
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 155 bits (392), Expect = 7e-38
Identities = 120/419 (28%), Positives = 183/419 (43%), Gaps = 81/419 (19%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
Query: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
PY P +P P+ GG DR G P +
Sbjct: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209
Query: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
S N L PP L AY G
Sbjct: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237
Query: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKDLAGS 401
+ S + M + G SG + S +G +G D + ++TIP DL G
Sbjct: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGC 297
Query: 402 IIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 298 IIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 356
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 39.7 bits (91), Expect = 0.006
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
+K+I + E G+ +P S P+
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 155 bits (392), Expect = 7e-38
Identities = 120/423 (28%), Positives = 186/423 (43%), Gaps = 85/423 (20%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
Query: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
KG PY P +P P+ GG DR G P +
Sbjct: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213
Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
S N L PP L AY G
Sbjct: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237
Query: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKD 397
+ S + M + G SG + S +G +G D + ++TIP D
Sbjct: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPND 297
Query: 398 LAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
L G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ +
Sbjct: 298 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSS 357
Query: 458 YSG 460
+G
Sbjct: 358 ETG 360
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKIIPTLEEGLQLPSP 117
+K+I + E L P
Sbjct: 158 CVKQICVVMLETLSQSPP 175
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 155 bits (391), Expect = 1e-37
Identities = 121/420 (28%), Positives = 183/420 (43%), Gaps = 82/420 (19%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
Query: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
PY P +P P+ GG DR G P +
Sbjct: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209
Query: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
S N L PP L AY G
Sbjct: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237
Query: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAG 400
+ S + M + G SG + S +G + L TT ++TIP DL G
Sbjct: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIG 297
Query: 401 SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 298 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 357
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 39.7 bits (91), Expect = 0.006
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
+K+I + E G+ +P S P+
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 155 bits (391), Expect = 1e-37
Identities = 121/424 (28%), Positives = 186/424 (43%), Gaps = 86/424 (20%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
Query: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
KG PY P +P P+ GG DR G P +
Sbjct: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213
Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
S N L PP L AY G
Sbjct: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237
Query: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPK 396
+ S + M + G SG + S +G + L TT ++TIP
Sbjct: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPN 297
Query: 397 DLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVK 456
DL G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ +
Sbjct: 298 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLS 357
Query: 457 QYSG 460
+G
Sbjct: 358 SETG 361
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKIIPTLEEGLQLPSP 117
+K+I + E L P
Sbjct: 158 CVKQICVVMLETLSQSPP 175
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 139 bits (349), Expect = 7e-33
Identities = 121/425 (28%), Positives = 187/425 (44%), Gaps = 97/425 (22%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ + G +IG
Sbjct: 76 IDKLEEDINSSMTNSTAASRPPVT--------------------LRLVVPATQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
G KIKE+RE+T +++ + P+ST+R + I G P V EC+K ++L+ +S+SP
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP- 174
Query: 219 KGRAQ--PYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPS 276
+GR PY P P P+ GG DR G P +
Sbjct: 175 QGRVMTIPYQP---------------------MPASSPVICAGGQDRCSDAAG---YPHA 210
Query: 277 RRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGM 336
D + GPP G+ PL DL ++ R + M
Sbjct: 211 THDLE------GPPLDAYSIQGQHTIS----PL---------DLAKLNQVARQQSHFAMM 251
Query: 337 VGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT-QVTIP 395
G T + ID+ SP +G + L TT ++TIP
Sbjct: 252 HG----GTGFAGIDSSSPEV--------------------KGYWASLDASTQTTHELTIP 287
Query: 396 KDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSV 455
+L G IIG+ G I +IR SGA IKI P+EGS R +TITG+ I AQYL+ +
Sbjct: 288 NNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARL 347
Query: 456 KQYSG 460
G
Sbjct: 348 SSEKG 352
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K +RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ +++ E
Sbjct: 98 VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTE 157
Query: 100 ILKKIIPTLEEGL 112
+K+I + E L
Sbjct: 158 CVKQICLVMLETL 170
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 106 bits (265), Expect = 4e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
Query: 223 QPYDP 227
PY P
Sbjct: 176 IPYRP 180
Score = 69.7 bits (169), Expect = 5e-12
Identities = 36/79 (45%), Positives = 48/79 (60%)
Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
D + ++TIP DL G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+
Sbjct: 235 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSA 294
Query: 442 DQIQNAQYLLQNSVKQYSG 460
I AQYL+ + +G
Sbjct: 295 ASISLAQYLINVRLSSETG 313
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
Score = 48.5 bits (114), Expect = 1e-05
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 42/196 (21%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKI-------------IP------------------TLEEGLQLPSPTATS--QLPLE 126
+K+I IP T++ +P P T QL ++
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
Query: 127 SDAVECLNYQHYKGSDFDCELRLLIHQ-----SLAGGIIGVKGAKIKELRENTQTTIKLF 181
+ + D + H+ L G IIG +GAKI E+R+ + IK+
Sbjct: 218 QSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 277
Query: 182 QECCPHSTDRVVLIGG 197
STDR V I G
Sbjct: 278 NP-VEGSTDRQVTITG 292
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 106 bits (265), Expect = 4e-23
Identities = 59/189 (31%), Positives = 104/189 (55%), Gaps = 26/189 (13%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
Query: 219 KGRAQPYDP 227
KG PY P
Sbjct: 176 KGVTIPYRP 184
Score = 75.5 bits (184), Expect = 1e-13
Identities = 45/108 (41%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
Query: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
S + M + G SG + S +G + L TT ++TIP DL G IIG+ G +I +
Sbjct: 223 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 282
Query: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 283 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 330
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 46.2 bits (108), Expect = 6e-05
Identities = 59/215 (27%), Positives = 85/215 (39%), Gaps = 63/215 (29%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKI-----------------IP------------------TLEEGLQLPSPTAT---- 120
+K+I IP T++ +P P T
Sbjct: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQ 217
Query: 121 -----SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGV 162
S P +ES + E Y + G D + L I L G IIG
Sbjct: 218 LAMQQSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGR 275
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
+GAKI E+R+ + IK+ STDR V I G
Sbjct: 276 QGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITG 309
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 106 bits (265), Expect = 4e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
Query: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
Query: 223 QPYDP 227
PY P
Sbjct: 176 IPYRP 180
Score = 75.5 bits (184), Expect = 1e-13
Identities = 45/108 (41%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
Query: 355 SEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAGSIIGKGGQRIKQ 412
S + M + G SG + S +G + L TT ++TIP DL G IIG+ G +I +
Sbjct: 219 SHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 278
Query: 413 IRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 279 IRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
Score = 49.3 bits (116), Expect = 7e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R ITI G I
Sbjct: 96 PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI 155
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 59/211 (27%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
Query: 100 ILKKI-------------IP------------------TLEEGLQLPSPTAT-------- 120
+K+I IP T++ +P P T
Sbjct: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQ 217
Query: 121 -SQLP----------LESDAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAK 166
S P +ES + E Y + G D + L I L G IIG +GAK
Sbjct: 218 QSHFPMTHGNTGFSGIESSSPEVKGY--WAGLDASAQTTSHELTIPNDLIGCIIGRQGAK 275
Query: 167 IKELRENTQTTIKLFQECCPHSTDRVVLIGG 197
I E+R+ + IK+ STDR V I G
Sbjct: 276 INEIRQMSGAQIKIANP-VEGSTDRQVTITG 305
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
Query: 200 DRVVECIKIILDLISE 215
+ + + +I+D + E
Sbjct: 66 NAIFKAFAMIIDKLEE 81
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 106 bits (264), Expect = 5e-23
Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+ +K +R + A +++ + + PERI++I+ + I + I
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
Query: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
EE + + + ATS+ P+ LRL++ S G +IG
Sbjct: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
G+KIKE+RE+T +++ + P+ST+R V I G PD +++C+K I ++ ESP KG
Sbjct: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207
Query: 223 QPYDP 227
PY P
Sbjct: 208 IPYRP 212
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/76 (51%), Positives = 47/76 (61%)
Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
G+ S D P T ++TIP DL G IIG+ G +I +IR SGA IKI EGS +R I
Sbjct: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
Query: 436 TITGTQDQIQNAQYLL 451
TITGT I AQYL+
Sbjct: 342 TITGTPANISLAQYLI 357
Score = 54.7 bits (130), Expect = 2e-07
Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R +TI+GT D I
Sbjct: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
GSIIGK G+ +K++R ESGA I I E +RI+TITG D I A
Sbjct: 58 GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
Score = 43.1 bits (100), Expect = 5e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R+V I G
Sbjct: 41 GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
Query: 200 DRVVECIKII 209
D + + +I
Sbjct: 98 DAIFKAFAMI 107
Score = 40.0 bits (92), Expect = 0.004
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++IS + I +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
Query: 100 ILKKIIPTLEEGLQLPSPTATSQLP 124
+K+I + L SP + +P
Sbjct: 190 CVKQICVVM-----LESPPKGATIP 209
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 149 LLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRV 202
L I L G IIG +G KI E+R+ + IK+ S++R + I G P +
Sbjct: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANATEGSSERQITITGTPANI 350
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 99.8 bits (247), Expect = 5e-21
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
LR+L+ K G++IGK G+ +K +R +A +++ + S PERI +I+ + + I
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79
Query: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
L+E L P+ P LRL+I S G +IG
Sbjct: 80 AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120
Query: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
G KIKE+RE T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Query: 224 PYDPN 228
PY P+
Sbjct: 181 PYHPS 185
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295
Query: 442 DQIQNAQYLL 451
I AQYL+
Sbjct: 296 VSIALAQYLI 305
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
G++ P +T ++ IP GS+IGK G +IK+IR +GA +++ + L S +R +T++G
Sbjct: 95 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154
Query: 440 TQDQI 444
D I
Sbjct: 155 VPDAI 159
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
V LR+++ + G++IGK G IK +R A V V P ER +++S A I
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 96 TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
+ +I I+ + +G +P +P ++L L S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
AV G D + L+ L G +IG +G+KI E+R+ + IK+ +
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280
Query: 185 CPHSTDRVVLIGGKP 199
+ +R V I G P
Sbjct: 281 AEGAGERHVTITGSP 295
Score = 38.5 bits (88), Expect = 0.013
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
GSIIGK G+ +K+IR +S A I I E +RI TITG+ + +A
Sbjct: 30 GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 99.8 bits (247), Expect = 5e-21
Identities = 59/185 (31%), Positives = 93/185 (50%), Gaps = 20/185 (10%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
LR+L+ K G++IGK G+ +K +R +A +++ + S PERI +I+ + + I
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTAAVFHAVSMI 79
Query: 105 IPTLEEGL-QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVK 163
L+E L P+ P LRL+I S G +IG
Sbjct: 80 AFKLDEDLCAAPANGGNVSRP-------------------PVTLRLVIPASQCGSLIGKA 120
Query: 164 GAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQ 223
G KIKE+RE T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG
Sbjct: 121 GTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Query: 224 PYDPN 228
PY P+
Sbjct: 181 PYHPS 185
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 295
Query: 442 DQIQNAQYLL 451
I AQYL+
Sbjct: 296 VSIALAQYLI 305
Score = 51.6 bits (122), Expect = 1e-06
Identities = 24/65 (36%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITG 439
G++ P +T ++ IP GS+IGK G +IK+IR +GA +++ + L S +R +T++G
Sbjct: 95 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSG 154
Query: 440 TQDQI 444
D I
Sbjct: 155 VPDAI 159
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 39/195 (20%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSIS----ADIE 95
V LR+++ + G++IGK G IK +R A V V P ER +++S A I
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 96 TIGEILKKIIPTLEEGLQLP---------------------------SPTATSQL-PLES 127
+ +I I+ + +G +P +P ++L L S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 128 DAVECLNYQHYKGSDFDCEL---RLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
AV G D + L+ L G +IG +G+KI E+R+ + IK+ +
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ- 280
Query: 185 CPHSTDRVVLIGGKP 199
+ +R V I G P
Sbjct: 281 AEGAGERHVTITGSP 295
Score = 38.5 bits (88), Expect = 0.013
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 2/48 (4%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
GSIIGK G+ +K+IR +S A I I E +RI TITG+ + +A
Sbjct: 30 GSIIGKKGETVKRIREQSSARITISE--GSCPERITTITGSTAAVFHA 75
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 93.6 bits (231), Expect = 3e-19
Identities = 52/174 (29%), Positives = 95/174 (54%), Gaps = 22/174 (12%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
+R+L+ K G++IGK G+ +K +R + A +++ + + PERI++I+ + I + I
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
Query: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
EE + + + ATS+ P+ LRL++ S G +IG
Sbjct: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
Query: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
G+KIKE+RE+T +++ + P+ST+R V I G PD +++C+K I ++ E+
Sbjct: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA 201
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/76 (51%), Positives = 47/76 (61%)
Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435
G+ S D P T ++TIP DL G IIG+ G +I +IR SGA IKI EGS +R I
Sbjct: 256 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 315
Query: 436 TITGTQDQIQNAQYLL 451
TITGT I AQYL+
Sbjct: 316 TITGTPANISLAQYLI 331
Score = 54.7 bits (130), Expect = 2e-07
Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444
P +T ++ +P GS+IGKGG +IK+IR +GA +++ + L S +R +TI+GT D I
Sbjct: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
Score = 49.7 bits (117), Expect = 6e-06
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 41/198 (20%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
V LR+++ + G++IGKGG IK +R A V V P ER ++IS + I +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
Query: 100 ILKKIIP------TLEEGLQLPSPTAT------------------------SQLPLESDA 129
+K+I T++ +P P T +LPL S +
Sbjct: 190 CVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHS-S 248
Query: 130 VECLNYQHYKGSDFDCE-----LRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC 184
E N + S D L I L G IIG +G KI E+R+ + IK+
Sbjct: 249 EEAQNLMG-QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANA 306
Query: 185 CPHSTDRVVLIGGKPDRV 202
S++R + I G P +
Sbjct: 307 TEGSSERQITITGTPANI 324
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Query: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447
GSIIGK G+ +K++R ESGA I I E +RI+TITG D I A
Sbjct: 58 GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
Score = 43.1 bits (100), Expect = 5e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
G + +RLL+H G IIG KG +K++RE + I + + CP +R+V I G
Sbjct: 41 GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
Query: 200 DRVVECIKII 209
D + + +I
Sbjct: 98 DAIFKAFAMI 107
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 70.5 bits (171), Expect = 3e-12
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)
Query: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
Query: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134
S ER+ I +E + + I + E +P A +++ V L
Sbjct: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
Query: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191
Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R
Sbjct: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
Query: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220
VV + G+P++ + +++I+ I E P G
Sbjct: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
Query: 448 QYLLQNSVKQYSG 460
QYL+ + G
Sbjct: 461 QYLITQRITYEQG 473
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
Query: 448 QYLLQNSVKQ 457
+ +++
Sbjct: 113 HGFIAEKIRE 122
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
Query: 449 YLLQNSVKQ 457
L+ +++
Sbjct: 211 ELIIQKIQE 219
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 70.5 bits (171), Expect = 3e-12
Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 22/207 (10%)
Query: 21 KRPAEDMEEEQAFKRSRNTDEMVE--LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
KRP E E KRS NT E E L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 10 KRPLETPPEVVCTKRS-NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKL 68
Query: 79 PDSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECL 133
S ER+ + E + + I + E Q + + V L
Sbjct: 69 SKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVRE---------IPQAMTKPEVVNIL 119
Query: 134 NYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHS---TD 190
Q D + +L++ S AG IIG GA +K + E + ++L Q+ P +
Sbjct: 120 QPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PEGINLQE 177
Query: 191 RVVLIGGKPDRVVECIKIILDLISESP 217
RVV + G+P++V + + I+ + E P
Sbjct: 178 RVVTVSGEPEQVHKAVSAIVQKVQEDP 204
Score = 53.5 bits (127), Expect = 4e-07
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 28/118 (23%)
Query: 371 YSYAGGRGSYGDLGGPIITT-------------------------QVTIPKDLAGSIIGK 405
Y AG G G GGP++ ++ +P++L G+I+GK
Sbjct: 365 YLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGK 424
Query: 406 GGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
GG+ + + + +GA I+I E L G+ +R +TITG+ Q AQYL+ V G
Sbjct: 425 GGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQG 482
Score = 49.7 bits (117), Expect = 6e-06
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ + GT + +
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 448 QYLLQNSVKQ 457
+ V++
Sbjct: 96 HSFIAEKVRE 105
Score = 48.1 bits (113), Expect = 2e-05
Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
++ +P AG IIGKGG +K + +SGA +++ + EG ++R++T++G +Q+ A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 449 YLLQNSVKQ 457
+ V++
Sbjct: 194 SAIVQKVQE 202
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 115 PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENT 174
P + + PLE+ + G + + L++LI AG IIG G I +L++ T
Sbjct: 3 PEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKET 62
Query: 175 QTTIKL--FQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESP 217
TIKL ++ P +T+RV L+ G + + I + + E P
Sbjct: 63 GATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIP 107
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 70.1 bits (170), Expect = 4e-12
Identities = 94/423 (22%), Positives = 159/423 (37%), Gaps = 104/423 (24%)
Query: 55 GAVIGKGGKNIKALRTDYNASVSV-PDSSG-PERILSISADIETIGEILKKIIPTLEEGL 112
G +IG+GG+ I ++ D V + PDS G PER +S++ E++ + + + G
Sbjct: 157 GLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGR 216
Query: 113 QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRE 172
P + + G ++I AG +IG G IK+L+E
Sbjct: 217 GGPPGQF---------------HDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQE 261
Query: 173 NTQTTIKLFQECCPHST-DRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYD 231
+ L Q+ ++ D+ + I G P +V + ++++D++ E
Sbjct: 262 RAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRER--------------- 306
Query: 232 ETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPP--------GRGGRPMPPSRRDYDDM 283
D GGF G + R GG D P GR G + + D
Sbjct: 307 ---DQGGF--------GDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQND---- 351
Query: 284 SPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGG----DLMAYDRRGRPGDRYDGMVGF 339
G G G + ++ PP DL+ R G PG
Sbjct: 352 ---AGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPG--------- 399
Query: 340 SADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAG---GRGSYGDLGGPIITTQVTIPK 396
P GG G G G+G++G GG + +IP
Sbjct: 400 -----------------------PPGGPGMPPGGRGRGRGQGNWGPPGGEMT---FSIPT 433
Query: 397 DLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSED---RIITITGTQDQIQNAQYLLQN 453
G +IG+GG+ +K I ++GA ++I L + D ++ I G+ QI +A+ L++
Sbjct: 434 HKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
Query: 454 SVK 456
++
Sbjct: 494 KIE 496
Score = 67.4 bits (163), Expect = 3e-11
Identities = 57/220 (25%), Positives = 86/220 (39%), Gaps = 43/220 (19%)
Query: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDL------------------ 320
DY P GPPPP G GG GG+ PPP PP GD
Sbjct: 3 DYSTGGPPPGPPPPAGGGGGAGGAGGG----PPPGPPGAGDRGGGGPGGGGPGGGSAGGP 58
Query: 321 MAYDRRGRPGDRYDGM-------------VGFSADETWDSAIDTWSPSEWQMAYEPQGGS 367
G PG R D +G A T +++ + + E G
Sbjct: 59 SQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLE-DGDQ 117
Query: 368 GYDYSYAGGRGSYGDLGGPI-------ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGAS 420
A S GPI +T + +P + G IIG+GG++I +I+ +SG
Sbjct: 118 PESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCK 177
Query: 421 IKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
++I G +R +++TG + +Q A+ +L + V + G
Sbjct: 178 VQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRG 217
Score = 37.0 bits (84), Expect = 0.038
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQNAQ 448
++ IP AG +IGKGG+ IKQ++ +G + + D + D+ + I G ++Q A
Sbjct: 237 EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQAC 296
Query: 449 YLLQNSVKQ 457
++ + +++
Sbjct: 297 EMVMDILRE 305
Score = 29.6 bits (65), Expect = 6.0
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 44 ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
E+ + + G VIG+GG+N+KA+ A V +
Sbjct: 426 EMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEI 460
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 66.6 bits (161), Expect = 4e-11
Identities = 105/472 (22%), Positives = 169/472 (35%), Gaps = 125/472 (26%)
Query: 21 KRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKN--------------AGAVIGKGGKNI 65
KRP ED ++ A K + D +L + Q ++ G +IG+GG+ I
Sbjct: 64 KRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQI 123
Query: 66 KALRTDYNASVSV-PDSSG-PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQL 123
++ + + + PDS G PER ++ E++ + + +E+G P
Sbjct: 124 SRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPG------- 176
Query: 124 PLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQE 183
H+ + ++I S AG +IG G IK+L+E + + Q+
Sbjct: 177 ------------FHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
Query: 184 CCPHST--DRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTM 241
P +T D+ + I G P +V + +++L+LI D GGF
Sbjct: 225 -GPQNTGADKPLRITGDPYKVQQAKEMVLELIR--------------------DQGGFRE 263
Query: 242 MFDDRRGRPVGFPMRGRGGFDRMPP--------GRGGRPMPPSRRDYD---DMSPRRGPP 290
+ ++ G + G G D P GR G + + D P G
Sbjct: 264 VRNE-----YGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTT 318
Query: 291 PPPPGRGGRGGSRARNLPLPPPPPPRGG----DLMAYDRRGRPGDRYDGMVGFSADETWD 346
P R + PP DL+ + G PG G G +
Sbjct: 319 P----------ERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQ--- 365
Query: 347 SAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKG 406
W M P GG + +P G IIGKG
Sbjct: 366 --------GNWNMG--PPGG--------------------LQEFNFIVPTGKTGLIIGKG 395
Query: 407 GQRIKQIRHESGASIKIDE---PLEGSEDRIITITGTQDQIQNAQYLLQNSV 455
G+ IK I +SGA I++ P ++ TI GT QI A+ L++ +
Sbjct: 396 GETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/71 (35%), Positives = 44/71 (61%)
Query: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
++T + +P + G IIG+GG++I +I+ ESG I+I G +R +TGT + +Q+
Sbjct: 100 VMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQS 159
Query: 447 AQYLLQNSVKQ 457
A+ LL V++
Sbjct: 160 AKRLLDQIVEK 170
Score = 45.4 bits (106), Expect = 1e-04
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 3/83 (3%)
Query: 380 YGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITI 437
+GD G + ++ IP AG +IGKGG+ IKQ++ +G + + D P D+ + I
Sbjct: 179 HGDGPGNAVQ-EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRI 237
Query: 438 TGTQDQIQNAQYLLQNSVKQYSG 460
TG ++Q A+ ++ ++ G
Sbjct: 238 TGDPYKVQQAKEMVLELIRDQGG 260
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/80 (30%), Positives = 43/80 (53%)
Query: 377 RGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIIT 436
R YG G V IP+ G +IG+ G+ IK+I++++G I+ + +RI
Sbjct: 265 RNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQ 324
Query: 437 ITGTQDQIQNAQYLLQNSVK 456
ITG D+ Q+A ++ + ++
Sbjct: 325 ITGPPDRCQHAAEIITDLLR 344
Score = 36.2 bits (82), Expect = 0.065
Identities = 63/274 (22%), Positives = 98/274 (35%), Gaps = 42/274 (15%)
Query: 55 GAVIGKGGKNIKALRTDYNASVSVPDSSG--PERILSISAD---IETIGEILKKIIPTLE 109
G VIG+ G+ IK ++ D + G PERI I+ + EI+ ++ +++
Sbjct: 288 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQ 347
Query: 110 EGLQL-PSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
G P P + + + N G E ++ G IIG G IK
Sbjct: 348 AGNPGGPGPGGRGRGRGQGN----WNMGPPGGLQ---EFNFIVPTGKTGLIIGKGGETIK 400
Query: 169 ELRENTQTTIKLFQECCPHSTDRVVL--IGGKPDRVVECIKIILDLISESPIKGRAQPYD 226
+ + + I+L + P++ + L I G P ++ ++I E I G P
Sbjct: 401 SISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLI-----EEKIGGPVNPLG 455
Query: 227 PNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPR 286
P + G P G P PPG G P + Y+ P
Sbjct: 456 PPVPHGPHGVPG-----------PHGPPG---------PPGPGTPMGPYNPAPYNPGPPG 495
Query: 287 RGP--PPPPPGRGGRGGSRARNLPLPPPPPPRGG 318
P PP P G G + PP P + G
Sbjct: 496 PAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAG 529
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 63.5 bits (153), Expect = 4e-10
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 48/235 (20%)
Query: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
Query: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQ--------------------- 113
S ER+ I +E + + I + E Q
Sbjct: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDR 146
Query: 114 ----LP-SPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIK 168
LP SPT T P + N ++++++ S AG IIG GA +K
Sbjct: 147 IKQTLPSSPTTTKSSPSDPMTTSRAN-----------QVKIIVPNSTAGLIIGKGGATVK 195
Query: 169 ELRENTQTTIKLFQECCP---HSTDRVVLIGGKPDRVVECIKIILDLISESPIKG 220
+ E + ++L Q+ P + +RVV + G+P++ + +++I+ I E P G
Sbjct: 196 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 248
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 425 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 484
Query: 448 QYLLQNSVKQYSG 460
QYL+ + G
Sbjct: 485 QYLITQRITYEQG 497
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
Query: 448 QYLLQNSVKQ 457
+ +++
Sbjct: 113 HGFIAEKIRE 122
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 175 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 234
Query: 449 YLLQNSVKQ 457
L+ +++
Sbjct: 235 ELIIQKIQE 243
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 63.2 bits (152), Expect = 5e-10
Identities = 108/451 (23%), Positives = 166/451 (36%), Gaps = 98/451 (21%)
Query: 21 KRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP- 79
KRP +D Q + E + K G +IG+GG+ I ++ + + +
Sbjct: 57 KRPLDDGVGNQLGALVHQRTVITE-EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIAS 115
Query: 80 DSSG-PERILSISADIETIGE---ILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNY 135
+SSG PER ++ E+I + +L +I+ G P + + S E
Sbjct: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNG-----PGFHNDIDSNSTIQE---- 166
Query: 136 QHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQEC-CPHSTDRVVL 194
+LI S G +IG G IK+L+E T + + Q+ P D+ +
Sbjct: 167 -------------ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLR 213
Query: 195 IGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGR---PV 251
I G +V + +++L++I E + D+ G F+ R G V
Sbjct: 214 ITGDAFKVQQAREMVLEIIREK---------------DQADFRGVRGDFNSRMGGGSIEV 258
Query: 252 GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPP 311
P G + GR G + + D G R + P
Sbjct: 259 SVPRFAVG----IVIGRNGEMIKKIQND--------------------AGVRIQFKPDDG 294
Query: 312 PPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDY 371
P R +M P DR A I T A E G G
Sbjct: 295 ISPERAAQVMG------PPDRCQ-----HAAHIISELILT--------AQERDGFGGLAA 335
Query: 372 SYAGGRG----SYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPL 427
+ GRG S G GG + T+P D G +IGKGG+ IK I +SGA +++
Sbjct: 336 ARGRGRGRGDWSVGAPGG-VQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNP 394
Query: 428 EGSED---RIITITGTQDQIQNAQYLLQNSV 455
+ D R TI G QI+ A+ L+ V
Sbjct: 395 PPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDR 433
G G + D+ ++ IP G +IG+GG+ IKQ++ +G + + D PL D+
Sbjct: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
Query: 434 IITITGTQDQIQNAQYLLQNSVKQ 457
+ ITG ++Q A+ ++ +++
Sbjct: 211 PLRITGDAFKVQQAREMVLEIIRE 234
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 44 ELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV----PDSSGPE-RILSISADIETIG 98
E+ + + G VIGKGG+NIK++ A V + P +S P R +I + I
Sbjct: 356 EITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQI- 414
Query: 99 EILKKIIPTLEEGLQLPSPTATSQLP 124
E+ +++I G L +P A Q P
Sbjct: 415 EVARQLIDEKVGGTNLGAPGAFGQSP 440
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 58.9 bits (141), Expect = 9e-09
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 28/194 (14%)
Query: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
+++R DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 130 EQTRQADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 188
Query: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
Query: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
Query: 187 HSTDRVVLIGGKPD 200
S R+V+I G P+
Sbjct: 309 DSKVRMVIITGPPE 322
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
Query: 450 LLQNSVKQ 457
+ +K+
Sbjct: 330 RIYGKLKE 337
Score = 35.4 bits (80), Expect = 0.11
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 408
Query: 446 NAQYLLQNSVKQ 457
AQ +++ + Q
Sbjct: 409 MAQRKIRDILAQ 420
Score = 32.3 bits (72), Expect = 0.93
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/70 (42%), Positives = 42/70 (60%)
Query: 382 DLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQ 441
D G + + +P DL G +IG+ G +I +IR SGA IKI EG+ +R +TITG+
Sbjct: 257 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSP 316
Query: 442 DQIQNAQYLL 451
I AQYL+
Sbjct: 317 VSIALAQYLI 326
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/57 (35%), Positives = 34/57 (59%)
Query: 172 ENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPN 228
+ T +++ + P+ST+R V + G PD ++ C++ I +I ESP KG PY P+
Sbjct: 150 QTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPS 206
Score = 37.0 bits (84), Expect = 0.038
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 381 GDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESG 418
G++ P +T ++ IP GS+IGK G +IK+IR G
Sbjct: 61 GNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIREVRG 98
Score = 34.3 bits (77), Expect = 0.25
Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 20/101 (19%)
Query: 73 NASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGL-QLPSPTATSQLPLESDAVE 131
+A +++ + S PERI +I+ + + I L+E L P+ P
Sbjct: 14 SARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRP------- 66
Query: 132 CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRE 172
LRL+I S G +IG G KIKE+RE
Sbjct: 67 ------------PVTLRLVIPASQCGSLIGKAGTKIKEIRE 95
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 58.2 bits (139), Expect = 2e-08
Identities = 52/194 (26%), Positives = 84/194 (43%), Gaps = 28/194 (14%)
Query: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
K ++ DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 269 KDTKTADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 327
Query: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 328 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 387
Query: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 388 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 447
Query: 187 HSTDRVVLIGGKPD 200
S R+V+I G P+
Sbjct: 448 DSKVRMVIITGPPE 461
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/212 (18%), Positives = 86/212 (40%), Gaps = 30/212 (14%)
Query: 11 PNTETNGEFGKRPAEDMEEEQAFKRSRNTDEM-VELRILLQSKNAGAVIGKGGKNIKALR 69
P G FG R A ++ + LR+L+ ++ GA+IGK G I+ +
Sbjct: 163 PENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNIT 222
Query: 70 TDYNASVSV---PDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLE 126
+ + V ++ E+ +S+ + E K I+ + + + ++P
Sbjct: 223 KQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHK--EAKDTKTADEVP-- 278
Query: 127 SDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQT--TIKLFQEC 184
L++L H + G +IG +G +K++ ++T+T TI Q+
Sbjct: 279 --------------------LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 318
Query: 185 CPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
++ +R + + G + + I+ + E+
Sbjct: 319 TLYNPERTITVKGAIENCCRAEQEIMKKVREA 350
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
Query: 450 LLQNSVKQ 457
+ +K+
Sbjct: 469 RIYGKLKE 476
Score = 35.4 bits (80), Expect = 0.11
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 547
Query: 446 NAQYLLQNSVKQ 457
AQ +++ + Q
Sbjct: 548 MAQRKIRDILAQ 559
Score = 32.3 bits (72), Expect = 0.93
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 488 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 530
Score = 30.8 bits (68), Expect = 2.7
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 351 TWSPSEWQMAYEPQGGSGYDYSYAGG--RGSYGDLGGPIITTQVTIPKDL------AGSI 402
++ P E Q+A P+ G + G +GS G P QV IP L G+I
Sbjct: 152 SYIPDE-QIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAI 210
Query: 403 IGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQNA 447
IGK G I+ I ++ + I + + G+ ++ I++ T + +A
Sbjct: 211 IGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSA 256
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 56.2 bits (134), Expect = 6e-08
Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 29/188 (15%)
Query: 41 EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
E + L+IL + G +IGK G+N+K + D + +++ PER +++ ++E
Sbjct: 275 EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVE 334
Query: 96 TIG----EILKKIIPTLEE-------------GLQLPS----PTATSQLPLESDAVECLN 134
T EI+KKI + E GL L + P + P S +
Sbjct: 335 TCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT 394
Query: 135 --YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRV 192
Y ++ S+ + + L I G IIG +G IK+L +IK+ P + R+
Sbjct: 395 PPYPQFEQSETET-VHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRM 453
Query: 193 VLIGGKPD 200
V+I G P+
Sbjct: 454 VIITGPPE 461
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 29/177 (16%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
LR+L+ ++ GA+IGK G I+ + + + V ++ E+ ++I + E
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAAC 257
Query: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
K I+ + + Q T ++P L++L H + G +IG
Sbjct: 258 KSILEIMHKEAQ--DIKFTEEIP----------------------LKILAHNNFVGRLIG 293
Query: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISES 216
+G +K++ ++T T TI QE ++ +R + + G + + + I+ I ES
Sbjct: 294 KEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES 350
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 389 TTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQN 446
T + IP G+IIGK GQ IKQ+ +GASIKI P E ++ R++ ITG +
Sbjct: 407 TVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKI-APAEAPDAKVRMVIITGPPEAQFK 465
Query: 447 AQYLLQNSVKQ 457
AQ + +K+
Sbjct: 466 AQGRIYGKIKE 476
Score = 37.4 bits (85), Expect = 0.029
Identities = 20/70 (28%), Positives = 37/70 (52%)
Query: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
D LRLL+ G IIG +GA I+ + + TQ+ I + ++ + ++ + I P+
Sbjct: 195 DLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTS 254
Query: 204 ECIKIILDLI 213
K IL+++
Sbjct: 255 AACKSILEIM 264
Score = 37.0 bits (84), Expect = 0.038
Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
+ + +P AG +IGKGG+ + ++++ S A + + D+ + ++ ++ ITG Q
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ 547
Query: 446 NAQYLLQNSVKQ 457
AQ +Q + Q
Sbjct: 548 VAQRKIQEILTQ 559
Score = 33.5 bits (75), Expect = 0.42
Identities = 18/43 (41%), Positives = 24/43 (55%)
Query: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
+E I + S AG VIGKGGK + L+ +A V VP P+
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPD 530
Score = 31.2 bits (69), Expect = 2.1
Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 362 EPQGGSGYDYSYAGGRGSYGDLGGPI---ITTQVTIPKDLAGSIIGKGGQRIKQIRHESG 418
+P+G G + +GS G + + ++ +P G+IIGK G I+ I ++
Sbjct: 167 QPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQ 226
Query: 419 ASIKID-EPLEGSEDRIITITGTQD 442
+ I + + G+ ++ ITI T +
Sbjct: 227 SKIDVHRKENAGAAEKSITILSTPE 251
>gi|5730027 KH domain containing, RNA binding, signal transduction
associated 1 [Homo sapiens]
Length = 443
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/134 (33%), Positives = 55/134 (41%), Gaps = 18/134 (13%)
Query: 247 RGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGP----------PPPPPGR 296
RGR G P+RGRG PP GR + P R +P RG PPPP
Sbjct: 282 RGR--GVPVRGRGAAPPPPPVPRGRGVGPPRGALVRGTPVRGAITRGATVTRGVPPPPTV 339
Query: 297 GGRGGSRAR-----NLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDT 351
G RAR +PLPPPP P + YD Y+G G+ + DS
Sbjct: 340 RGAPAPRARTAGIQRIPLPPPPAPETYEEYGYDDT-YAEQSYEGYEGYYSQSQGDSEYYD 398
Query: 352 WSPSEWQMAYEPQG 365
+ E Q +YE G
Sbjct: 399 YGHGEVQDSYEAYG 412
Score = 37.4 bits (85), Expect = 0.029
Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 267 GRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSR--ARNLPLPPPPP 314
GR G P +P R PP P RGG GGSR AR P PPP
Sbjct: 16 GRSGSMDPSGAHPSVRQTPSRQPPLPHRSRGGGGGSRGGARASPATQPPP 65
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/169 (25%), Positives = 74/169 (43%), Gaps = 10/169 (5%)
Query: 41 EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
E + L+IL + G +IGK G+N+K + + +++ PER +++ +E
Sbjct: 273 EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVE 332
Query: 96 TIG----EILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
EI+KK+ E + L T + + + H+ + L I
Sbjct: 333 ACASAEIEIMKKLREAFENDM-LAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFI 391
Query: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD 200
G IIG KGA IK+L +IK+ P ++R+V+I G P+
Sbjct: 392 PTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPE 440
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 29/158 (18%)
Query: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
LRIL+ ++ GA+IGK G IK + + V + +S E+ ++I A E E
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
Query: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
+ I+ +++ E+D + + L++L H L G +IG
Sbjct: 256 RMILEIMQK---------------EADETKLAE---------EIPLKILAHNGLVGRLIG 291
Query: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGG 197
+G +K++ T T TI Q+ ++ +R + + G
Sbjct: 292 KEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKG 329
Score = 42.7 bits (99), Expect = 7e-04
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 394 IPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSE--DRIITITGTQDQIQNAQYLL 451
IP G+IIGK G IKQ+ +GASIKI P EG + +R++ ITG + AQ +
Sbjct: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSERMVIITGPPEAQFKAQGRI 449
Query: 452 QNSVKQ 457
+K+
Sbjct: 450 FGKLKE 455
Score = 39.3 bits (90), Expect = 0.008
Identities = 19/72 (26%), Positives = 39/72 (54%)
Query: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
D LR+L+ G IIG +G IK + + TQ+ + + ++ + ++ V I P+
Sbjct: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
Query: 204 ECIKIILDLISE 215
E ++IL+++ +
Sbjct: 253 EACRMILEIMQK 264
Score = 39.3 bits (90), Expect = 0.008
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 26/165 (15%)
Query: 33 FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILS 89
F + E + + + ++ GA+IGK G +IK L AS+ + + GP ER++
Sbjct: 375 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 434
Query: 90 ISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRL 149
I+ E + +I L+E N+ + K + E +
Sbjct: 435 ITGPPEAQFKAQGRIFGKLKEE----------------------NFFNPK-EEVKLEAHI 471
Query: 150 LIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVL 194
+ S AG +IG G + EL+ T + + ++ P + V++
Sbjct: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 516
Score = 38.5 bits (88), Expect = 0.013
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGS---EDRIITITGTQDQI 444
I ++ L G +IGK G+ +K+I HE+G I I + S +R IT+ GT +
Sbjct: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
Query: 445 QNAQYLLQNSVKQ 457
+A+ + +++
Sbjct: 335 ASAEIEIMKKLRE 347
Score = 37.7 bits (86), Expect = 0.022
Identities = 19/72 (26%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
+ + +P AG +IGKGG+ + ++++ + A + + D+ + +E+ I+ I G Q
Sbjct: 467 LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQ 526
Query: 446 NAQYLLQNSVKQ 457
AQ ++ V+Q
Sbjct: 527 TAQRKIREIVQQ 538
Score = 36.2 bits (82), Expect = 0.065
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 19 FGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
FGK ++EE F +E I + S AG VIGKGGK + L+ +A V V
Sbjct: 450 FGK-----LKEENFFNPKEEVK--LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV 502
Query: 79 PDSSGPE 85
P P+
Sbjct: 503 PRDQTPD 509
Score = 33.1 bits (74), Expect = 0.55
Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 10/122 (8%)
Query: 327 GRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGP 386
G + Y + + DE + SPS Q A S GG + P
Sbjct: 142 GHQFENYSFKISYIPDE------EVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFP 195
Query: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQ 445
+ ++ +P G+IIGK G IK I ++ + + I + G+ ++ +TI T +
Sbjct: 196 L---RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
Query: 446 NA 447
A
Sbjct: 253 EA 254
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 53.5 bits (127), Expect = 4e-07
Identities = 54/155 (34%), Positives = 60/155 (38%), Gaps = 23/155 (14%)
Query: 248 GRPVGFPMRGRGG------FDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPG-----R 296
G P+ P G GG PP RGG P D P RG P P PG R
Sbjct: 648 GGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 297 GGRGGSRARNLPLPPPPPP----RGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTW 352
GGRGG+ PPPPPP RGG GR G GMVG +
Sbjct: 708 GGRGGNEP-----PPPPPPFRGARGGRSGGGPPNGRGGPG-GGMVGGGGHRPHEGPGGGM 761
Query: 353 SPSEWQMAYE-PQGGSGYDY-SYAGGRGSYGDLGG 385
S +E P GG G + + G GS G GG
Sbjct: 762 GNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGG 796
Score = 43.5 bits (101), Expect = 4e-04
Identities = 46/165 (27%), Positives = 55/165 (33%), Gaps = 23/165 (13%)
Query: 244 DDRRGRPV-GFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGS 302
D RG P+ G P G G + R GRGG PP + R PP GRGG GG
Sbjct: 685 DPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGG 744
Query: 303 RARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYE 362
P P GG M RP + G +G +
Sbjct: 745 MVGGGGHRPHEGPGGG--MGNSSGHRPHEGPGGGMG--------------------SGHR 782
Query: 363 PQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGG 407
P G G GG + GG I P + G +G GG
Sbjct: 783 PHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGG 827
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/71 (43%), Positives = 31/71 (43%), Gaps = 24/71 (33%)
Query: 252 GFPMRGRGG---FDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLP 308
GFP G GG PPG GG PMP P GP GG G R
Sbjct: 628 GFPPGGPGGPKGMQHFPPGPGG-PMP---------GPHGGP-------GGPVGPRL---- 666
Query: 309 LPPPPPPRGGD 319
L PPPPPRGGD
Sbjct: 667 LGPPPPPRGGD 677
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 51.6 bits (122), Expect = 1e-06
Identities = 48/143 (33%), Positives = 57/143 (39%), Gaps = 56/143 (39%)
Query: 217 PIKGRAQP-------YDPNFY------DETYDY------GGFTMMFDDRRGRPVGFPMRG 257
PI+GR + Y P++Y D+ Y Y GG+ D G G+ +RG
Sbjct: 347 PIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYE---DPYYGYDDGYAVRG 403
Query: 258 RGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRG-----GRGGSRARNLPLPPP 312
RGG GRGGR G PPPP GRG GR G R PL PP
Sbjct: 404 RGG------GRGGR----------------GAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 441
Query: 313 PPPRGGDLMAYDRRGRPGDRYDG 335
RGG RG P + G
Sbjct: 442 RGSRGG-------RGGPAQQQRG 457
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 51.6 bits (122), Expect = 1e-06
Identities = 48/143 (33%), Positives = 57/143 (39%), Gaps = 56/143 (39%)
Query: 217 PIKGRAQP-------YDPNFY------DETYDY------GGFTMMFDDRRGRPVGFPMRG 257
PI+GR + Y P++Y D+ Y Y GG+ D G G+ +RG
Sbjct: 448 PIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYE---DPYYGYDDGYAVRG 504
Query: 258 RGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRG-----GRGGSRARNLPLPPP 312
RGG GRGGR G PPPP GRG GR G R PL PP
Sbjct: 505 RGG------GRGGR----------------GAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 542
Query: 313 PPPRGGDLMAYDRRGRPGDRYDG 335
RGG RG P + G
Sbjct: 543 RGSRGG-------RGGPAQQQRG 558
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,307,077
Number of Sequences: 37866
Number of extensions: 1571237
Number of successful extensions: 16421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 8891
Number of HSP's gapped (non-prelim): 4716
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.