Search of human proteins with 91208437

Search of human proteins with 91208437

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91208437 GEM interacting protein [Homo sapiens]
         (970 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91208437 GEM interacting protein [Homo sapiens]                   1967   0.0  
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]      478   e-134
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]                 477   e-134
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                     132   2e-30
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                    132   2e-30
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]            128   3e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]          126   1e-28
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                      113   1e-24
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                       113   1e-24
gi|156119615 myosin IXA [Homo sapiens]                                112   1e-24
gi|188497642 ARHGAP15 [Homo sapiens]                                  104   5e-22
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]           102   1e-21
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          102   2e-21
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...   102   2e-21
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...   102   2e-21
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]            101   3e-21
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s...    99   2e-20
gi|4505507 oligophrenin 1 [Homo sapiens]                               99   2e-20
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    99   2e-20
gi|23510413 sorting nexin 26 [Homo sapiens]                            98   3e-20
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]         98   4e-20
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]         98   4e-20
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           97   6e-20
gi|229094128 active breakpoint cluster region-related  protein i...    97   7e-20
gi|38679957 active breakpoint cluster region-related  protein is...    97   7e-20
gi|38679954 active breakpoint cluster region-related  protein is...    97   7e-20
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...    96   2e-19
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...    96   2e-19
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...    95   3e-19
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...    95   3e-19

>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score = 1967 bits (5097), Expect = 0.0
 Identities = 970/970 (100%), Positives = 970/970 (100%)

Query: 1   MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATV 60
           MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATV
Sbjct: 1   MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATV 60

Query: 61  TNEASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRAS 120
           TNEASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRAS
Sbjct: 61  TNEASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRAS 120

Query: 121 YELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQP 180
           YELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQP
Sbjct: 121 YELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQP 180

Query: 181 LAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAP 240
           LAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAP
Sbjct: 181 LAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAP 240

Query: 241 QASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLV 300
           QASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLV
Sbjct: 241 QASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLV 300

Query: 301 FQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPP 360
           FQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPP
Sbjct: 301 FQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPP 360

Query: 361 PPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTPG 420
           PPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTPG
Sbjct: 361 PPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTPG 420

Query: 421 SDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLGDGLENGLGS 480
           SDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLGDGLENGLGS
Sbjct: 421 SDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLGDGLENGLGS 480

Query: 481 PFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHR 540
           PFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHR
Sbjct: 481 PFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHR 540

Query: 541 RLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQ 600
           RLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQ
Sbjct: 541 RLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQ 600

Query: 601 AFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGT 660
           AFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGT
Sbjct: 601 AFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGT 660

Query: 661 PSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLR 720
           PSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLR
Sbjct: 661 PSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLR 720

Query: 721 PPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL 780
           PPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL
Sbjct: 721 PPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL 780

Query: 781 TTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDT 840
           TTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDT
Sbjct: 781 TTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDT 840

Query: 841 KDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPI 900
           KDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPI
Sbjct: 841 KDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPI 900

Query: 901 TSVPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPD 960
           TSVPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPD
Sbjct: 901 TSVPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPD 960

Query: 961 VQPEEAEDHL 970
           VQPEEAEDHL
Sbjct: 961 VQPEEAEDHL 970


>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
          Length = 1136

 Score =  478 bits (1229), Expect = e-134
 Identities = 329/911 (36%), Positives = 464/911 (50%), Gaps = 91/911 (9%)

Query: 23   RSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATVTNEASCWSGPSPEGPVP----- 77
            ++L+ + ++  +   E L G+    +       P    +       GP  EG  P     
Sbjct: 205  KALETIAVAFSSTVSEFLMGEV---DSSTLLAVPPGDSSQSMESLYGPGSEGTPPSLEDC 261

Query: 78   ----LTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIA 133
                L  EE+D+ L R +GGVDAAL YAK  ++Y K+L+++ EKR + E+EFAK   KIA
Sbjct: 262  DAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIA 321

Query: 134  EAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQ-QKRDYYQPLAAKRTEIEKWR 192
               + S+ Q+ HMPL  IY+L LE DL  G   ++ V   Q + + QPL  +R E EK R
Sbjct: 322  HNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRR 381

Query: 193  KEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSED------LRARSQGSPEDSAPQASPGP 246
            KE KE W + Q+++ EA   LR+A+  YVQR ED      L A+++     SAP A    
Sbjct: 382  KEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTA 441

Query: 247  SKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEV 306
            +K  ++RRR  EEA+ KA+EA A Y+ CV +A  ++Q+LE  K   +  +++++ Q D+ 
Sbjct: 442  TKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQT 501

Query: 307  LRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPPPPAFSF 366
            ++  T+S + +   Q    P  F  L E    ++PGQ+Y   VR L+ +  P     + F
Sbjct: 502  IKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVH--YDF 559

Query: 367  QEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTP----GSD 422
            +  + +   SP+   +K S  +       +A   P E   T    +GTP        G  
Sbjct: 560  EPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCT----EGTPAKDHRAGRGHQ 615

Query: 423  VDSVGGGSESRSLDSPTSSPGAGT-RQLVKASSTGTESSDDFEERDPDLGDGLE------ 475
            V      S S S       PGAG  ++  + SS+GT SS + E  DPD G G        
Sbjct: 616  VHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTE-ELVDPDGGAGASAFEQAD 674

Query: 476  -NGL---------GSPFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMV-SGTECEECFLT 524
             NG+           PF    LS AA+TH+LR+LR PAKCREC +++   G ECEEC L 
Sbjct: 675  LNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLA 734

Query: 525  CHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQG 584
            CHK+CLETL I CGH++L  R  LFG DF    R  P+ VPF+V KC  EIE RAL  +G
Sbjct: 735  CHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKG 794

Query: 585  IYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFI 644
            IYRV+G + RVE+LCQAFENG+ LVELS  SPHD+S+VLK +L++L EP+I F LY   +
Sbjct: 795  IYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELV 854

Query: 645  SLAK--------TLHADPGDDPGTPSPSPEVIRS--LKTLLVQLPDSNYNTLRHLVAHLF 694
             LAK           A  G   G+ S +  V  +  L+ LL  LP  N  +L++L+ HL 
Sbjct: 855  GLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLR 914

Query: 695  RVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYE 754
            R+     +NKM+  NLGIVFGPTLLRP       + + ++ L+D  HQA+++E LIVHY 
Sbjct: 915  RIVEVEQDNKMTPGNLGIVFGPTLLRPRP---TEATVSLSSLVDYPHQARVIETLIVHYG 971

Query: 755  QIFGMDELPQATEPPPQDSS---------------------------PAPGPLTTSSQPP 787
             +F  +E P+ T P  QD S                            A G   +     
Sbjct: 972  LVF--EEEPEET-PGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSN 1028

Query: 788  PPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEV 847
                D +    +L+S       H S LEQ  +    E+ +      E+  E T    G+ 
Sbjct: 1029 DSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDG 1088

Query: 848  SSQGPEDSLLG 858
               GP   L G
Sbjct: 1089 DEDGPAQQLSG 1099


>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
          Length = 1261

 Score =  477 bits (1228), Expect = e-134
 Identities = 302/788 (38%), Positives = 443/788 (56%), Gaps = 64/788 (8%)

Query: 18  YSDIFRSLDNLEISLGNVTLEMLAGD---PLLSEDPEPDKTPTATVTNEASCWSGPSPEG 74
           + ++F S++ L  + GN+    L GD     L   P   +T +    +  S  S      
Sbjct: 129 FQEVFSSIETLAFTFGNILTNFLMGDVGNDSLLRLPVSRETKSFENVSVESVDSSSEKGN 188

Query: 75  PVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAE 134
             PL   ELD  L++    ++ AL YAKTWS+Y K +++W EK+ + ELE  ++ +K+AE
Sbjct: 189 FSPL---ELDNVLLKNTDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNMVKLAE 245

Query: 135 AGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQ-QKRDYYQPLAAKRTEIEKWRK 193
           A + +I  Q  MPLQ ++T  L +D+    L  +T+A  Q   + QPL  ++ E+EK RK
Sbjct: 246 ATRTNIGIQEFMPLQSLFTNALLNDIESSHLLQQTIAALQANKFVQPLLGRKNEMEKQRK 305

Query: 194 EFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDL-RARSQGSPEDSAPQASPGP-----S 247
           E KE W +EQ +M EA  AL++A+L  +QR ++  +A+S     +    +S G      +
Sbjct: 306 EIKELWKQEQNKMLEAENALKKAKLLCMQRQDEYEKAKSSMFRAEEEHLSSSGGLAKNLN 365

Query: 248 KQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVL 307
           KQ E++RR  EEA  K +EA  LY+ CV     R+ DLE  K+ I++ +R LVFQ D  L
Sbjct: 366 KQLEKKRRLEEEALQKVEEANELYKVCVTNVEERRNDLENTKREILAQLRTLVFQCDLTL 425

Query: 308 RRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRA---------------- 351
           + VT++LF ++  QA     +  +L +    ++PGQ Y EFV+A                
Sbjct: 426 KAVTVNLFHMQHLQAASLADSLQSLCDSAKLYDPGQEYSEFVKATNSTEEEKVDGNVNKH 485

Query: 352 LRPEAPPPPPPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRW 411
           L    P    PA S ++ +   +SS      + S         NSA+       G  +  
Sbjct: 486 LNSSQPSGFGPANSLEDVVRLPDSSNKIEEDRCS---------NSADI-----TGPSFIR 531

Query: 412 QGTPGPTPGSDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESS-DDFEERDPDL 470
             T G    SD +S GG SESRSLDS + SPG   R+L +  S+GT SS DD +ER+P  
Sbjct: 532 SWTFGMF--SDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPS 589

Query: 471 -GDGLENGLGSPFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMV-SGTECEECFLTCHKR 528
             +   N LG+ F K  +S AA TH+ R+LR P KCR+CE  +V  G ECEEC L CH++
Sbjct: 590 PSETGPNSLGT-FKKTLMSKAALTHKFRKLRSPTKCRDCEGIVVFQGVECEECLLVCHRK 648

Query: 529 CLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRV 588
           CLE L+I+CGH++LP +  LFG +F Q+ +  P+ +PF++  C +EIE+RAL +QGIYRV
Sbjct: 649 CLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYRV 708

Query: 589 SGSRVRVERLCQAFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAK 648
            G++++ E+LCQA ENG  LV++S  S HD+  VLK +L++L EP I F LY  FI LAK
Sbjct: 709 CGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAK 768

Query: 649 TLH---------ADPGDDPGTPSPSPEVIRSL---KTLLVQLPDSNYNTLRHLVAHLFRV 696
            +           +  +D   P+   E+ R L   K LL QLP SN+N+L  L+ HL RV
Sbjct: 769 EIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVHLKRV 828

Query: 697 AARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQI 756
                ENKM++ NLG++FGP+L+RP       + I ++ L +  +QA+LVEFLI + ++I
Sbjct: 829 VDHAEENKMNSKNLGVIFGPSLIRPRP---TTAPITISSLAEYSNQARLVEFLITYSQKI 885

Query: 757 FGMDELPQ 764
           F     PQ
Sbjct: 886 FDGSLQPQ 893


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score =  132 bits (331), Expect = 2e-30
 Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 28/275 (10%)

Query: 492 QTHQLR--RLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPAR 545
           +TH  +    RGP  C  C  FM      G  C +C L  HK+C + +   C    L   
Sbjct: 213 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 271

Query: 546 TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605
             ++  D   L +    + P VV  C  EIE R L  +G+YRVSG    +E +  AF+  
Sbjct: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331

Query: 606 RALVELSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPS 662
               ++S N   D++ +   LK + ++L  PVI +  Y  FI  AK  +AD         
Sbjct: 332 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNAD--------- 382

Query: 663 PSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPP 722
              E + ++  +L+ LP ++Y TLR+L+ HL +V     +N M+A NLGIVFGPTL+RPP
Sbjct: 383 ---ERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 439

Query: 723 DGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
           +         +T L D  +Q  +V+ LI + + +F
Sbjct: 440 EDS------TLTTLHDMRYQKLIVQILIENEDVLF 468


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score =  132 bits (331), Expect = 2e-30
 Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 28/275 (10%)

Query: 492 QTHQLR--RLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPAR 545
           +TH  +    RGP  C  C  FM      G  C +C L  HK+C + +   C    L   
Sbjct: 77  KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 135

Query: 546 TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605
             ++  D   L +    + P VV  C  EIE R L  +G+YRVSG    +E +  AF+  
Sbjct: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195

Query: 606 RALVELSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPS 662
               ++S N   D++ +   LK + ++L  PVI +  Y  FI  AK  +AD         
Sbjct: 196 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNAD--------- 246

Query: 663 PSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPP 722
              E + ++  +L+ LP ++Y TLR+L+ HL +V     +N M+A NLGIVFGPTL+RPP
Sbjct: 247 ---ERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 303

Query: 723 DGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
           +         +T L D  +Q  +V+ LI + + +F
Sbjct: 304 EDS------TLTTLHDMRYQKLIVQILIENEDVLF 332


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score =  128 bits (321), Expect = 3e-29
 Identities = 100/310 (32%), Positives = 147/310 (47%), Gaps = 35/310 (11%)

Query: 464 EERDPDLGDGL-ENGLGSPFGKWTLSSAAQTHQLRRL--------RGPAKCRECEAFM-- 512
           +ERD    DG+ E  L S   + TL    Q  +  ++        RGP  C  C  FM  
Sbjct: 169 DERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWG 228

Query: 513 --VSGTECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTK 570
               G +C +C L  HK+C + +   C    L     ++  D   L +    + P VV  
Sbjct: 229 LIAQGVKCADCGLNVHKQCSKMVPNDC-KPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDM 287

Query: 571 CTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSV---LKRFL 627
           C  EIE R L+ +G+YRVSG    +E +  AF+      ++S N   D++ +   LK + 
Sbjct: 288 CIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYF 347

Query: 628 QELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLR 687
           ++L  P+I +  Y  FI  AK +  D            E + +L   L  LP ++  TLR
Sbjct: 348 RDLPIPLITYDAYPKFIESAKIMDPD------------EQLETLHEALKLLPPAHCETLR 395

Query: 688 HLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVE 747
           +L+AHL RV     EN M+A NLGIVFGPTL+R P+    A+      L D  +Q  +VE
Sbjct: 396 YLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAA------LNDIRYQRLVVE 449

Query: 748 FLIVHYEQIF 757
            LI + + +F
Sbjct: 450 LLIKNEDILF 459


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score =  126 bits (316), Expect = 1e-28
 Identities = 89/270 (32%), Positives = 132/270 (48%), Gaps = 26/270 (9%)

Query: 495 QLRRLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPARTPLFG 550
           ++   RGP  C  C  FM      G +C +C L  HK+C + +   C    L     ++ 
Sbjct: 183 RVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDC-KPDLKHVKKVYS 241

Query: 551 VDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVE 610
            D   L +    + P VV  C  EIE R L+ +G+YRVSG    +E +  AF+      +
Sbjct: 242 CDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKAD 301

Query: 611 LSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEV 667
           +S N   D++ +   LK + ++L  P+I +  Y  FI  AK +  D            E 
Sbjct: 302 ISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPD------------EQ 349

Query: 668 IRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRA 727
           + +L   L  LP ++  TLR+L+AHL RV     EN M+A NLGIVFGPTL+R P+    
Sbjct: 350 LETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAM 409

Query: 728 ASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
           A+      L D  +Q  +VE LI + + +F
Sbjct: 410 AA------LNDIRYQRLVVELLIKNEDILF 433


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score =  113 bits (282), Expect = 1e-24
 Identities = 81/257 (31%), Positives = 121/257 (47%), Gaps = 26/257 (10%)

Query: 502  PAKCRECEAF---MVSGTECEECFLTCHKRCLETLLILC----GHRRLPARTP-LFGVDF 553
            P  C +C ++   M     C  C +TCHK+C+  +   C    G +  P   P  FGV  
Sbjct: 1643 PQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCV 1702

Query: 554  LQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSG 613
              L  D    VP V+ K    +E   L  +G+YR SG+  R   L QA +   A V+L  
Sbjct: 1703 DSLTSD-KASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLEN 1761

Query: 614  NSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKT 673
               H ++ VLK++L+EL EP++ F  Y  F+   +                 E + ++  
Sbjct: 1762 FPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVEL------------PEKQEQLAAIYA 1809

Query: 674  LLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPV 733
            +L  LP++N+N+L  L+ HL +VA     N+MS   L I+F P LLR PD     ++ P+
Sbjct: 1810 VLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPD-----NSDPL 1864

Query: 734  TCLLDSGHQAQLVEFLI 750
            T + D       VE LI
Sbjct: 1865 TSMKDVLKITTCVEMLI 1881


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score =  113 bits (282), Expect = 1e-24
 Identities = 81/257 (31%), Positives = 121/257 (47%), Gaps = 26/257 (10%)

Query: 502  PAKCRECEAF---MVSGTECEECFLTCHKRCLETLLILC----GHRRLPARTP-LFGVDF 553
            P  C +C ++   M     C  C +TCHK+C+  +   C    G +  P   P  FGV  
Sbjct: 1643 PQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCV 1702

Query: 554  LQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSG 613
              L  D    VP V+ K    +E   L  +G+YR SG+  R   L QA +   A V+L  
Sbjct: 1703 DSLTSD-KASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLEN 1761

Query: 614  NSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKT 673
               H ++ VLK++L+EL EP++ F  Y  F+   +                 E + ++  
Sbjct: 1762 FPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVEL------------PEKQEQLAAIYA 1809

Query: 674  LLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPV 733
            +L  LP++N+N+L  L+ HL +VA     N+MS   L I+F P LLR PD     ++ P+
Sbjct: 1810 VLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPD-----NSDPL 1864

Query: 734  TCLLDSGHQAQLVEFLI 750
            T + D       VE LI
Sbjct: 1865 TSMKDVLKITTCVEMLI 1881



 Score = 30.8 bits (68), Expect = 6.4
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 3/76 (3%)

Query: 765  ATEPPPQDSSPAPGPLTTSSQP---PPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTAT 821
            A+E PP  + P PG  T S  P    PP   P S   V    P   P   +   + P   
Sbjct: 2017 ASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGL 2076

Query: 822  PTEIPTPQSDQREDVA 837
            P+ +P      RE  A
Sbjct: 2077 PSHLPRWAPGAREAAA 2092


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score =  112 bits (281), Expect = 1e-24
 Identities = 78/254 (30%), Positives = 119/254 (46%), Gaps = 22/254 (8%)

Query: 502  PAKCRECEAF---MVSGTECEECFLTCHKRCLETLLILCGHRRLPARTPL-FGVDFLQLP 557
            P  C  C +    M   + C+ C   CHK+C       C  +  P  +   FGV+  +L 
Sbjct: 2010 PTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLT 2069

Query: 558  RDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPH 617
             +    VP VV K    IE   L  +GIYR SGS  +++ L Q  +     V L   + H
Sbjct: 2070 SE-DRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIH 2128

Query: 618  DVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQ 677
             ++SV K++L++L  P++ F LY+ F+                     E IR + +++ Q
Sbjct: 2129 VIASVFKQWLRDLPNPLMTFELYEEFLRAMGL------------QERKETIRGVYSVIDQ 2176

Query: 678  LPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLL 737
            L  ++ NTL  L+ HL R+A +   N+MSAN L IVF P +LR PD     +  P+  + 
Sbjct: 2177 LSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPD-----TTDPLQSVQ 2231

Query: 738  DSGHQAQLVEFLIV 751
            D       VE ++V
Sbjct: 2232 DISKTTTCVELIVV 2245


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  104 bits (259), Expect = 5e-22
 Identities = 68/200 (34%), Positives = 104/200 (52%), Gaps = 21/200 (10%)

Query: 564 VPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAF--ENGRALVELSGNSPHDVSS 621
           VP+ V +C   +E R LDV GIYRVSG+   +++L      E    L +      H V+ 
Sbjct: 294 VPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTG 353

Query: 622 VLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDS 681
            LK F +EL EP+ P+  ++ F+   K        D  T       I ++K+L+ +LP  
Sbjct: 354 ALKMFFRELPEPLFPYSFFEQFVEAIKK------QDNNTR------IEAVKSLVQKLPPP 401

Query: 682 NYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGH 741
           N +T++ L  HL ++ A+  +N MS  +LGIVFGPTLLR  +      AI +       +
Sbjct: 402 NRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR-AENETGNMAIHMV------Y 454

Query: 742 QAQLVEFLIVHYEQIFGMDE 761
           Q Q+ E ++  Y +IFG +E
Sbjct: 455 QNQIAELMLSEYSKIFGSEE 474


>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
          Length = 786

 Score =  102 bits (255), Expect = 1e-21
 Identities = 74/229 (32%), Positives = 115/229 (50%), Gaps = 35/229 (15%)

Query: 567 VVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHD-----VSS 621
           ++ KC + +E R ++ QG+YRV G   +V+RL     + +   E+   +  D     ++S
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457

Query: 622 VLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEV-IRSLKTLLVQLPD 680
            LK++L+ L EP++ + L+  FI  AK             S SPE  + ++  L+ +LP+
Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAK-------------SGSPESRVNAIHFLVHKLPE 504

Query: 681 SNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSG 740
            N   L  LV HL  V+    +N M+  NLG+VFGPTL+RP +   AA       L+D  
Sbjct: 505 KNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAA-------LMDLK 557

Query: 741 HQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLTTSSQPPPP 789
            Q  +VE LI ++E+IF           PP  + P P  L+ S    PP
Sbjct: 558 FQNIVVEILIENHEKIF---------RTPPDTTFPEPTCLSASPPNAPP 597


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  102 bits (254), Expect = 2e-21
 Identities = 80/243 (32%), Positives = 116/243 (47%), Gaps = 26/243 (10%)

Query: 543  PARTPLFGVDFLQLPRDFPEE-VPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQA 601
            P  T  FGV     P       +P +V  C   +E R L+  GIYRV G+   +  + + 
Sbjct: 1139 PTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEE 1198

Query: 602  FENGRALVELSGNSPHD---VSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDP 658
               G A +++  +   D   +SS+LK F ++L EP+     Y  FI       A+  +DP
Sbjct: 1199 LNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIE------ANRKEDP 1252

Query: 659  GTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTL 718
                   + +++LK L+  LP+ +Y TL+ L AHL  VA    +NKM   NL IVFGPTL
Sbjct: 1253 ------LDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTL 1306

Query: 719  LRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF---GMDE-LPQATEPPPQDSS 774
            +R  +         VT + D   Q ++VE LI H++  F   G +E L    E    DS 
Sbjct: 1307 VRTSEDNMTHM---VTHMPD---QYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQ 1360

Query: 775  PAP 777
            P P
Sbjct: 1361 PVP 1363


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score =  102 bits (253), Expect = 2e-21
 Identities = 84/288 (29%), Positives = 133/288 (46%), Gaps = 30/288 (10%)

Query: 538 GHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
           G ++  A+  +FG D  +  +   +EVP V+  C   +E   + V GIYR+SG    +++
Sbjct: 7   GKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNIQK 65

Query: 598 LCQAFENGRA---LVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADP 654
           L Q FE+ R      ++     H VSS+ K + +EL +P++ + LYD F           
Sbjct: 66  LRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV----- 120

Query: 655 GDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVF 714
                     PE +  +  +L +LP  NY TL  L+ HL  +A+   +  M A NL IV+
Sbjct: 121 -------QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVW 173

Query: 715 GPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSS 774
            P LLR  D   A+        ++   Q+ +VEF++ H +Q+FG   L          S 
Sbjct: 174 APNLLRSKD-IEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSL 232

Query: 775 P----APGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQ---HHSTLE 815
           P    +  P     +P P HL     P +L +  GP PQ   +H+ +E
Sbjct: 233 PGTRASGSPEDLMPRPLPYHL-----PSILQAGDGP-PQMRPYHTIIE 274


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score =  102 bits (253), Expect = 2e-21
 Identities = 84/288 (29%), Positives = 133/288 (46%), Gaps = 30/288 (10%)

Query: 538 GHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
           G ++  A+  +FG D  +  +   +EVP V+  C   +E   + V GIYR+SG    +++
Sbjct: 7   GKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNIQK 65

Query: 598 LCQAFENGRA---LVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADP 654
           L Q FE+ R      ++     H VSS+ K + +EL +P++ + LYD F           
Sbjct: 66  LRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV----- 120

Query: 655 GDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVF 714
                     PE +  +  +L +LP  NY TL  L+ HL  +A+   +  M A NL IV+
Sbjct: 121 -------QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVW 173

Query: 715 GPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSS 774
            P LLR  D   A+        ++   Q+ +VEF++ H +Q+FG   L          S 
Sbjct: 174 APNLLRSKD-IEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSL 232

Query: 775 P----APGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQ---HHSTLE 815
           P    +  P     +P P HL     P +L +  GP PQ   +H+ +E
Sbjct: 233 PGTRASGSPEDLMPRPLPYHL-----PSILQAGDGP-PQMRPYHTIIE 274


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score =  101 bits (252), Expect = 3e-21
 Identities = 74/220 (33%), Positives = 105/220 (47%), Gaps = 24/220 (10%)

Query: 561 PEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVS 620
           P   P +V +C   I  R L  +G++R+ G    V  L  +F+ G   +  S    H V+
Sbjct: 169 PRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVA 228

Query: 621 SVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPD 680
           S+LK +L+EL EPV+PF  Y+ F+S A+ L  D G+  GT   + +V          LP 
Sbjct: 229 SLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGE--GTLELAKQV--------SNLPQ 278

Query: 681 SNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSG 740
           +NYN LR++   L  V A    NKMS  NL  VFGP +LRP          PVT +  + 
Sbjct: 279 ANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRP------QVEDPVTIMEGTS 332

Query: 741 HQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPL 780
               L+  LI  + Q+F        T P P+  +   G L
Sbjct: 333 LVQHLMTVLIRKHSQLF--------TAPVPEGPTSPRGGL 364


>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
           sapiens]
          Length = 874

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 108/415 (26%), Positives = 177/415 (42%), Gaps = 53/415 (12%)

Query: 568 VTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRAL------VELSGNSPHDVSS 621
           V KC   +E R + + G+YR+ G   +V++L     + ++       +EL  N    ++S
Sbjct: 398 VRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKT--ITS 455

Query: 622 VLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDS 681
            LK +L+ L EP++ + L+  FI   K+      DD          + ++  L+ +LP+ 
Sbjct: 456 GLKNYLRCLAEPLMTYKLHKDFIIAVKS------DDQNYR------VEAVHALVHKLPEK 503

Query: 682 NYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGH 741
           N   L  L+ HL +V+    +N M+ +NLG++FGPTL+R       A    V  +++   
Sbjct: 504 NREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMR-------AQEETVAAMMNIKF 556

Query: 742 QAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGP----LTTSSQPP-----PPHLD 792
           Q  +VE LI HYE+IF     P    P PQ  S +       L+T S+ P     P   +
Sbjct: 557 QNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAE 616

Query: 793 PDSQPPVLASDPGPDPQHH-STLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEVSSQG 851
           PDS     +S P   P     +L  H +   +   +     RE      K GG  +    
Sbjct: 617 PDSDS--YSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPRE------KSGG--IPWIA 666

Query: 852 PEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQ--LSSLALVASKLCEETPITSVPRGSLR 909
              S  G +S G ++  P    R        +    S+A V S      PI  V +    
Sbjct: 667 TPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDLVKKEPYG 726

Query: 910 GRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPDVQPE 964
             G   A+A    S LR     +  +    + + L+ + S+  P+A+  PD+ P+
Sbjct: 727 LSGLKRASA----SSLRSISAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPK 777


>gi|4505507 oligophrenin 1 [Homo sapiens]
          Length = 802

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 96/391 (24%), Positives = 167/391 (42%), Gaps = 62/391 (15%)

Query: 568 VTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELS-GNSPHDVSSV---L 623
           V KC   IE + +  +G+YR  GS ++V++L  AF + +   ++   NS  D+ ++   L
Sbjct: 390 VRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSL 449

Query: 624 KRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNY 683
           K +L+ L+EPV+ + L+   +S AK+ + D              + ++ +L+ +LP+ N 
Sbjct: 450 KFYLRNLSEPVMTYRLHKELVSAAKSDNLDYR------------LGAIHSLVYKLPEKNR 497

Query: 684 NTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQA 743
             L  L+ HL  V     EN M+ +N+G++FGPTL+R       A    V  +++   Q 
Sbjct: 498 EMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMR-------AQEDTVAAMMNIKFQN 550

Query: 744 QLVEFLIVHYEQIF--GMDELPQATEPPPQDSSPAPGPLTTS-----------------S 784
            +VE LI H+ +I+    +E      PPP+ ++    P+T S                 S
Sbjct: 551 IVVEILIEHFGKIYLGPPEESAAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDES 610

Query: 785 QPPPPHLDPDSQPPVLASDPGPDPQHHSTL--------------EQHPTATPTEIPTPQS 830
           +    H  P+    + +S   P P  H  L                 P       P P+ 
Sbjct: 611 EDEIQHQTPNG--TITSSIEPPKPPQHPKLPIQRSGETDPGRKSPSRPILDGKLEPCPEV 668

Query: 831 DQREDVAEDTKDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALV 890
           D  + V+   +DGG +++ +     + G+   G          R   RP+ H     A  
Sbjct: 669 DVGKLVSR-LQDGGTKITPKATNGPMPGS---GPTKTPSFHIKRPAPRPLAHHKEGDADS 724

Query: 891 ASKLCEETPITSVPRGSLRGRGPSPAAASPE 921
            SK+       ++ R  +R   P   AA+P+
Sbjct: 725 FSKVRPPGEKPTIIRPPVRPPDPPCRAATPQ 755


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 81/252 (32%), Positives = 116/252 (46%), Gaps = 29/252 (11%)

Query: 561 PEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHD-- 618
           P +VP ++ KC  +IE R L V G+YR+ GS    + L  AFE   A V LS +   D  
Sbjct: 410 PGQVPLIIQKCVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLSEDLYPDIN 469

Query: 619 -VSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQ 677
            ++ +LK +L+EL  P+I   LY         L A   D P    P+ E  R    LL  
Sbjct: 470 VITGILKDYLRELPTPLITQPLYKV------VLEAMARDPPNRVPPTTEGTRG---LLSC 520

Query: 678 LPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLL---RPPDGPRAASAIP-V 733
           LPD    TL  L+ HL  V++    N+M+  NL + FGP LL   + P  PRA S+ P +
Sbjct: 521 LPDVERATLTLLLDHLRLVSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGL 580

Query: 734 TCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLTTSSQPPPPHLDP 793
              +D  H  +++ +L+  +             +P     SP   P     + PP HL P
Sbjct: 581 ASAVDFKHHIEVLHYLLQSW------------PDPRLPRQSPDVAPYLRPKRQPPLHL-P 627

Query: 794 DSQPPVLASDPG 805
            + P V+    G
Sbjct: 628 LADPEVVTRPRG 639


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 109/391 (27%), Positives = 167/391 (42%), Gaps = 53/391 (13%)

Query: 545 RTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFEN 604
           R  +FG D  +   +  ++VP V+  C+  IE   + V GIYR+SG    ++RL   F++
Sbjct: 309 RQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGV-VDGIYRLSGVSSNIQRLRHEFDS 367

Query: 605 GRALVELSG----NSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGT 660
            R + ELSG       H VSS+ K + +EL  P++ + LY  F          PG++   
Sbjct: 368 ER-IPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSV----PGEE--- 419

Query: 661 PSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLR 720
                E +  +  ++ QLP  +Y TL +L+ HL R+A       M A NL IV+ P LLR
Sbjct: 420 -----ERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLR 474

Query: 721 PPD----GPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPA 776
             +    G   A+A     +     Q+ +VEFL+ H + +F         +P  +   P 
Sbjct: 475 SMELESVGMGGAAAFREVRV-----QSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPR 529

Query: 777 PGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDV 836
           P  L  S         P ++   L        +      Q    TPTE  TP++      
Sbjct: 530 PKSLAGSC--------PSTRLLTL--------EEAQARTQGRLGTPTEPTTPKAP--ASP 571

Query: 837 AEDTKDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYP---RGGVR----PVTHQLSSLAL 889
           AE  K   GE   +    S     + G     P K P    GG R    P   +  ++ L
Sbjct: 572 AERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGSRPDTVTL 631

Query: 890 VASKLCEETPITSVPRGSLRGRGPSPAAASP 920
            ++K  EE+  +      L G G +PA+A+P
Sbjct: 632 RSAK-SEESLSSQASGAELLGAGGAPASATP 661


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 68/198 (34%), Positives = 98/198 (49%), Gaps = 18/198 (9%)

Query: 540  RRLPAR--TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
            +R+P+R  T +FGV    + +    +VP++V +C  EIE R ++  GIYRVSG    ++ 
Sbjct: 997  KRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQA 1056

Query: 598  LCQAFE--NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPG 655
            L  AF+  N    V +S    + ++  LK + +EL EP+     Y  F            
Sbjct: 1057 LKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE---------- 1106

Query: 656  DDPGTPSPSPEVIRS-LKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVF 714
               G     P    S +  LL+ LP++N  T   L+ HL RVA +   NKMS +NL  VF
Sbjct: 1107 ---GIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVF 1163

Query: 715  GPTLLRPPDGPRAASAIP 732
            GPTLLRP +      A P
Sbjct: 1164 GPTLLRPSEKESKLPANP 1181


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 68/198 (34%), Positives = 98/198 (49%), Gaps = 18/198 (9%)

Query: 540  RRLPAR--TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
            +R+P+R  T +FGV    + +    +VP++V +C  EIE R ++  GIYRVSG    ++ 
Sbjct: 1041 KRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQA 1100

Query: 598  LCQAFE--NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPG 655
            L  AF+  N    V +S    + ++  LK + +EL EP+     Y  F            
Sbjct: 1101 LKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAE---------- 1150

Query: 656  DDPGTPSPSPEVIRS-LKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVF 714
               G     P    S +  LL+ LP++N  T   L+ HL RVA +   NKMS +NL  VF
Sbjct: 1151 ---GIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVF 1207

Query: 715  GPTLLRPPDGPRAASAIP 732
            GPTLLRP +      A P
Sbjct: 1208 GPTLLRPSEKESKLPANP 1225


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 101/371 (27%), Positives = 149/371 (40%), Gaps = 59/371 (15%)

Query: 562  EEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHD--- 618
            + VP +V  C   +E R L+  GIYRV G+   V  L +    G   + L      D   
Sbjct: 823  QRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNV 882

Query: 619  VSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQL 678
            +SS+LK F ++L EP+     Y+ FI   +   A             E +R+L+ L+  L
Sbjct: 883  ISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDAR------------ERMRTLRKLIRDL 930

Query: 679  PDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLD 738
            P   Y TL+ LV HL  +A    +NKM   NL +VFGPTL+R  +         VT + D
Sbjct: 931  PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDM---VTHMPD 987

Query: 739  SGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLTTSSQPPPPHLDPDSQPP 798
               + ++VE LI H +  F  DE  +    P  D  P        + P   +L P+    
Sbjct: 988  ---RYKIVETLIQHSDWFFS-DEEDKGERTPVGDKEP-------QAVPNIEYLLPNIGRT 1036

Query: 799  VLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEVSSQGPEDSLLG 858
            V   DPG D    S+ +   +  P + P      RE +A            +  E   LG
Sbjct: 1037 VPPGDPGSDSTTCSSAKSKGSWAPKKEPY----AREMLAISFISAVNRKRKKRREARGLG 1092

Query: 859  TQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPITSVPRGSLRGRGPSPAAA 918
            + +     ++  K   G   P T +                         R +GP P A 
Sbjct: 1093 SSTDDDSEQEAHKPGAGATAPGTQE-------------------------RPQGPLPGAV 1127

Query: 919  SPEGSPLRRTP 929
            +PE +P R +P
Sbjct: 1128 APE-APGRLSP 1137


>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score = 97.1 bits (240), Expect = 7e-20
 Identities = 65/188 (34%), Positives = 96/188 (51%), Gaps = 16/188 (8%)

Query: 540 RRLPAR--TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
           +R P++  T +FGV    + +    +VP++V +C  E+E R ++  GIYR+SG    ++ 
Sbjct: 588 KRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQA 647

Query: 598 LCQAFE--NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPG 655
           L   F+  N   L+ LS    + ++  LK + +EL EP++   LY AF+           
Sbjct: 648 LKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIAL------ 701

Query: 656 DDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFG 715
            DP            +  LL  LPD N  T   L+ HL RVA +   NKMS +NL  VFG
Sbjct: 702 SDPAAKE------NCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFG 755

Query: 716 PTLLRPPD 723
           PTLLRP +
Sbjct: 756 PTLLRPSE 763


>gi|38679957 active breakpoint cluster region-related  protein
           isoform a [Homo sapiens]
          Length = 859

 Score = 97.1 bits (240), Expect = 7e-20
 Identities = 65/188 (34%), Positives = 96/188 (51%), Gaps = 16/188 (8%)

Query: 540 RRLPAR--TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
           +R P++  T +FGV    + +    +VP++V +C  E+E R ++  GIYR+SG    ++ 
Sbjct: 634 KRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQA 693

Query: 598 LCQAFE--NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPG 655
           L   F+  N   L+ LS    + ++  LK + +EL EP++   LY AF+           
Sbjct: 694 LKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIAL------ 747

Query: 656 DDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFG 715
            DP            +  LL  LPD N  T   L+ HL RVA +   NKMS +NL  VFG
Sbjct: 748 SDPAAKE------NCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFG 801

Query: 716 PTLLRPPD 723
           PTLLRP +
Sbjct: 802 PTLLRPSE 809


>gi|38679954 active breakpoint cluster region-related  protein
           isoform b [Homo sapiens]
          Length = 822

 Score = 97.1 bits (240), Expect = 7e-20
 Identities = 65/188 (34%), Positives = 96/188 (51%), Gaps = 16/188 (8%)

Query: 540 RRLPAR--TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVER 597
           +R P++  T +FGV    + +    +VP++V +C  E+E R ++  GIYR+SG    ++ 
Sbjct: 597 KRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQA 656

Query: 598 LCQAFE--NGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPG 655
           L   F+  N   L+ LS    + ++  LK + +EL EP++   LY AF+           
Sbjct: 657 LKAVFDANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIAL------ 710

Query: 656 DDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFG 715
            DP            +  LL  LPD N  T   L+ HL RVA +   NKMS +NL  VFG
Sbjct: 711 SDPAAKE------NCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFG 764

Query: 716 PTLLRPPD 723
           PTLLRP +
Sbjct: 765 PTLLRPSE 772


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 43/235 (18%)

Query: 545 RTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFEN 604
           R  +FG     L +   + VP  +  C A ++ R LDV GIYRVSG+   V++L    + 
Sbjct: 517 RDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDR 576

Query: 605 GRALVE--------------------LSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFI 644
            RA+                         +  H V+  LK FL+EL +P++P  L   F 
Sbjct: 577 ERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR 636

Query: 645 SLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENK 704
           +                S S + +  ++ L+  +P  N++TLR+L+ HL RV A   +N+
Sbjct: 637 AALAL------------SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNR 684

Query: 705 MSANNLGIVFGPTLLRPPD--GPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
           M+ +NLGIVFGPTL RP       AA A+         +  QLV+ ++ ++  +F
Sbjct: 685 MTPHNLGIVFGPTLFRPEQETSDPAAHAL---------YPGQLVQLMLTNFTSLF 730


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 43/235 (18%)

Query: 545 RTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFEN 604
           R  +FG     L +   + VP  +  C A ++ R LDV GIYRVSG+   V++L    + 
Sbjct: 333 RDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDR 392

Query: 605 GRALVE--------------------LSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFI 644
            RA+                         +  H V+  LK FL+EL +P++P  L   F 
Sbjct: 393 ERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFR 452

Query: 645 SLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENK 704
           +                S S + +  ++ L+  +P  N++TLR+L+ HL RV A   +N+
Sbjct: 453 AALAL------------SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNR 500

Query: 705 MSANNLGIVFGPTLLRPPD--GPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
           M+ +NLGIVFGPTL RP       AA A+         +  QLV+ ++ ++  +F
Sbjct: 501 MTPHNLGIVFGPTLFRPEQETSDPAAHAL---------YPGQLVQLMLTNFTSLF 546


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 68/212 (32%), Positives = 103/212 (48%), Gaps = 21/212 (9%)

Query: 548 LFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRA 607
           +FG     L       VP  V +C   +E R LD+ G+YR+SG+   +++L    ++   
Sbjct: 326 VFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDER 385

Query: 608 LVELSGN--SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSP 665
           L    G     H ++  LK F +EL EP+ PF  +  FI+  K        D    S   
Sbjct: 386 LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKL------QDQARRS--- 436

Query: 666 EVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGP 725
              R ++ L+  LP  N++TLR L  HL RV     +N+MS  ++ IVFGPTLLRP    
Sbjct: 437 ---RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRP---E 490

Query: 726 RAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
              +++P+T +     Q Q+VE ++     IF
Sbjct: 491 VEETSMPMTMVF----QNQVVELILQQCADIF 518


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 68/212 (32%), Positives = 103/212 (48%), Gaps = 21/212 (9%)

Query: 548 LFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRA 607
           +FG     L       VP  V +C   +E R LD+ G+YR+SG+   +++L    ++   
Sbjct: 353 VFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDER 412

Query: 608 LVELSGN--SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSP 665
           L    G     H ++  LK F +EL EP+ PF  +  FI+  K        D    S   
Sbjct: 413 LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKL------QDQARRS--- 463

Query: 666 EVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGP 725
              R ++ L+  LP  N++TLR L  HL RV     +N+MS  ++ IVFGPTLLRP    
Sbjct: 464 ---RCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRP---E 517

Query: 726 RAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
              +++P+T +     Q Q+VE ++     IF
Sbjct: 518 VEETSMPMTMVF----QNQVVELILQQCADIF 545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,595,997
Number of Sequences: 37866
Number of extensions: 2914662
Number of successful extensions: 26888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 917
Number of HSP's that attempted gapping in prelim test: 17443
Number of HSP's gapped (non-prelim): 8028
length of query: 970
length of database: 18,247,518
effective HSP length: 112
effective length of query: 858
effective length of database: 14,006,526
effective search space: 12017599308
effective search space used: 12017599308
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.