Guide to the Human Genome
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Search of human proteins with 8923394

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923394 transmembrane protein 161A [Homo sapiens]
         (479 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923394 transmembrane protein 161A [Homo sapiens]                  961   0.0  
gi|23503279 transmembrane protein 161B [Homo sapiens]                 466   e-131
gi|54792146 tripartite motif-containing 47 [Homo sapiens]              33   0.75 
gi|98991767 mitogen-activated protein kinase kinase kinase 7 int...    32   1.3  
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          32   1.7  
gi|22035562 RNA polymerase III transcription initiation factor B...    31   2.2  
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       31   2.2  
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       31   2.2  
gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]              30   3.7  
gi|8393378 frizzled 3 [Homo sapiens]                                   30   4.8  
gi|83281200 protogenin [Homo sapiens]                                  30   6.3  
gi|189571657 glycerophosphodiester phosphodiesterase domain cont...    30   6.3  

>gi|8923394 transmembrane protein 161A [Homo sapiens]
          Length = 479

 Score =  961 bits (2484), Expect = 0.0
 Identities = 479/479 (100%), Positives = 479/479 (100%)

Query: 1   MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGR 60
           MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGR
Sbjct: 1   MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGR 60

Query: 61  KERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFT 120
           KERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFT
Sbjct: 61  KERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFT 120

Query: 121 EAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLL 180
           EAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLL
Sbjct: 121 EAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLL 180

Query: 181 AMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGA 240
           AMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGA
Sbjct: 181 AMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGA 240

Query: 241 FLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGE 300
           FLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGE
Sbjct: 241 FLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGE 300

Query: 301 TRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREI 360
           TRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREI
Sbjct: 301 TRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREI 360

Query: 361 QQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPI 420
           QQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPI
Sbjct: 361 QQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPI 420

Query: 421 GSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS 479
           GSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS
Sbjct: 421 GSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS 479


>gi|23503279 transmembrane protein 161B [Homo sapiens]
          Length = 487

 Score =  466 bits (1199), Expect = e-131
 Identities = 235/485 (48%), Positives = 333/485 (68%), Gaps = 10/485 (2%)

Query: 1   MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRP-RG 59
           M V+G+QLVVT++ A++M ++ PH S ARWLLCNGSL  Y+HP+EEELR LAGK +  + 
Sbjct: 1   MGVIGIQLVVTMVMASVMQKIIPHYSLARWLLCNGSLRWYQHPTEEELRILAGKQQKGKT 60

Query: 60  RKERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLF 119
           +K+R  NG  E KPL++P+D    LET  +T VD L L +F EYQW VDF V +  VYL 
Sbjct: 61  KKDRKYNGHIESKPLTIPKDIDLHLETKSVTEVDTLALHYFPEYQWLVDFTVAATVVYLV 120

Query: 120 TEAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLL 179
           TE YY  + P +E NI++ WCLL ++F+IK+  ++T  YF  E+GGERSVC+TF F F +
Sbjct: 121 TEVYYNFMKPTQEMNISLVWCLLVLSFAIKVLFSLTTHYFKVEDGGERSVCVTFGFFFFV 180

Query: 180 LAMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLG 239
            AM V +V E  LE GLE G  + + +    L+KQG +   PV+KL  +  LA+  S +G
Sbjct: 181 KAMAVLIVTENYLEFGLETGFTNFSDSAMQFLEKQGLESQSPVSKLTFKFFLAIFCSFIG 240

Query: 240 AFLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFG 299
           AFLTFPGLRLAQ H DAL ++ ++ + Q LLH +FL+PLF++ LW KPI +D++  PP G
Sbjct: 241 AFLTFPGLRLAQMHLDALNLATEK-ITQTLLHINFLAPLFMVLLWVKPITKDYIMNPPLG 299

Query: 300 ETRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEARE 359
           +    L++++ FD+ RLWL+++LC LRLA+ R HLQAYL LA+  V+Q+++EAGRI   E
Sbjct: 300 KESIPLMTEATFDTLRLWLIILLCALRLAMMRSHLQAYLNLAQKCVDQMKKEAGRISTVE 359

Query: 360 IQQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGP-----APLLSPDPSS 414
           +Q+ V RV+ Y+ V++LQY+ PL++ L+ TLLLKTLG +SWG+ P      P+ +   S+
Sbjct: 360 LQKMVARVFYYLCVIALQYVAPLVMLLHTTLLLKTLGNHSWGIYPESISTLPVDNSLLSN 419

Query: 415 ASAAPIGSGEDEVQQTAARIAGALGGL---LTPLFLRGVLAYLIWWTAACQLLASLFGLY 471
           +  + + S E +++ T  +I  AL  L    TPL  RG+L++L WW AAC    SLFGL+
Sbjct: 420 SVYSELPSAEGKMKVTVTQITVALSSLKNIFTPLLFRGLLSFLTWWIAACLFSTSLFGLF 479

Query: 472 FHQHL 476
           +HQ+L
Sbjct: 480 YHQYL 484


>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
          Length = 638

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 17/35 (48%), Positives = 22/35 (62%)

Query: 385 TLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAP 419
           TL+  L L+   G   G GPAP L+P+PS+ SA P
Sbjct: 72  TLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALP 106


>gi|98991767 mitogen-activated protein kinase kinase kinase 7
           interacting protein 3 [Homo sapiens]
          Length = 712

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 19/114 (16%)

Query: 324 LLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLT--- 380
           LL        L   L L K  +E+L+ E   +E   +Q+R+ RV C   + + + +T   
Sbjct: 519 LLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLR 578

Query: 381 ----PLILTLNCTL----LLKTLGGYS--------WGLGPAPLLSPDPSSASAA 418
                L + ++CTL    LL++ G +           + P P++ P PS   ++
Sbjct: 579 SMNRQLQINVDCTLKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSS 632


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 10/67 (14%)

Query: 38   FRYKHPSEEELRALA---GKPRPRGRKERWAN-------GLSEEKPLSVPRDAPFQLETC 87
            F  + P+EE  + L    G P P G K++           +SE  P     D P + E C
Sbjct: 2110 FASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEEC 2169

Query: 88   PLTTVDA 94
            P  T DA
Sbjct: 2170 PSITADA 2176


>gi|22035562 RNA polymerase III transcription initiation factor BRF2
           [Homo sapiens]
          Length = 419

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 1/59 (1%)

Query: 341 AKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYS 399
           A A  +Q  R +G I A  +Q++ V V C V +   Q+  PL +   CTLL   L  +S
Sbjct: 93  AVAYYQQAYRHSG-IRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYADLDVFS 150


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 17/58 (29%), Positives = 29/58 (50%)

Query: 381  PLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPIGSGEDEVQQTAARIAGAL 438
            P  +++ CT L  +    +  LGP P+  P P S      G  +  ++QT++ +A AL
Sbjct: 1020 PKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAAL 1077


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 17/58 (29%), Positives = 29/58 (50%)

Query: 381  PLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPIGSGEDEVQQTAARIAGAL 438
            P  +++ CT L  +    +  LGP P+  P P S      G  +  ++QT++ +A AL
Sbjct: 1102 PKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAAL 1159


>gi|148839342 ATP-grasp domain containing 1 [Homo sapiens]
          Length = 827

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 1/42 (2%)

Query: 379 LTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPI 420
           LTP+ L LN  L L+  G    GL  AP L P    A AAP+
Sbjct: 338 LTPVALELNGGLCLEACGALE-GLWAAPRLGPAADEAVAAPL 378


>gi|8393378 frizzled 3 [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 7/77 (9%)

Query: 312 DSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYV 371
           D+ R ++L  LCL  +      L   + L + R+E           +E Q ++V+    +
Sbjct: 369 DALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLE-------KENQDKLVKFMIRI 421

Query: 372 TVVSLQYLTPLILTLNC 388
            V S+ YL PL++ + C
Sbjct: 422 GVFSILYLVPLLVVIGC 438


>gi|83281200 protogenin [Homo sapiens]
          Length = 1150

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 13/35 (37%), Positives = 19/35 (54%)

Query: 254 RDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPI 288
           R  + MSEDRP   + +H   +S   IL  W +P+
Sbjct: 409 RLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPL 443


>gi|189571657 glycerophosphodiester phosphodiesterase domain
           containing 5 [Homo sapiens]
          Length = 605

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 352 AGRIEAREIQQRVVRVYC-YVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLG--PAPLL 408
           AG+    E     V + C + TVV   YL PL ++  C +  K LG     +G   AP+L
Sbjct: 180 AGQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPML 239

Query: 409 SPD 411
           +P+
Sbjct: 240 APE 242


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,201,882
Number of Sequences: 37866
Number of extensions: 835449
Number of successful extensions: 3269
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3257
Number of HSP's gapped (non-prelim): 15
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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