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Search of human proteins with 8923271
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
(425 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923271 coiled-coil domain containing 49 [Homo sapiens] 844 0.0
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 86 5e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 71 2e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 71 2e-12
gi|148746195 trichohyalin [Homo sapiens] 67 4e-11
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 65 9e-11
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 64 3e-10
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 61 2e-09
gi|122937227 U2-associated SR140 protein [Homo sapiens] 61 2e-09
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 60 5e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 59 8e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 8e-09
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 59 8e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 59 1e-08
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 59 1e-08
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 58 1e-08
gi|62244004 modulator of estrogen induced transcription isoform ... 57 2e-08
gi|63176611 modulator of estrogen induced transcription isoform ... 57 2e-08
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 57 2e-08
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 57 2e-08
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-08
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-08
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 57 3e-08
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 56 5e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 55 9e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 55 9e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 55 9e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 55 1e-07
>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
Length = 425
Score = 844 bits (2181), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDV 60
MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDV
Sbjct: 1 MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDV 60
Query: 61 GAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFA 120
GAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFA
Sbjct: 61 GAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFA 120
Query: 121 PSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKK 180
PSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKK
Sbjct: 121 PSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKK 180
Query: 181 EKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGL 240
EKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGL
Sbjct: 181 EKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGL 240
Query: 241 QGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK 300
QGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK
Sbjct: 241 QGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK 300
Query: 301 LHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL 360
LHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL
Sbjct: 301 LHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL 360
Query: 361 NILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEK 420
NILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEK
Sbjct: 361 NILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEK 420
Query: 421 NFMKR 425
NFMKR
Sbjct: 421 NFMKR 425
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 86.3 bits (212), Expect = 5e-17
Identities = 103/419 (24%), Positives = 170/419 (40%), Gaps = 112/419 (26%)
Query: 9 KKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEE 68
KK +HP + N++KVW AEQK ++KK EEL ++ +E+ + + D ++ +
Sbjct: 11 KKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGD----ERVKN 66
Query: 69 KLDWMYQGPGGMVNRD--------------EYLLGRPIDKYVFEKME------------- 101
L++MY+ P G + E+ G P +KY + M
Sbjct: 67 GLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNV 126
Query: 102 -------------EKEAGCSSETGLLPGSIFAPSGANSL--LDMASKIRE---------- 136
++E +G+ S+ S+ ++ +++R
Sbjct: 127 RCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVL 186
Query: 137 -------DPL--FIIRKKEEEKKREVLNNPVKMKKIKELLQMS-LEKKEKKKKKEKKK-- 184
DP ++ + EE+ + E L + +K K L ++ LEKK+KKK ++KKK
Sbjct: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
Query: 185 ----KHKKHKHRSSSSD----RSSSEDEHSAGRS-----QKKMANSSPVLSKVPGYG--- 228
KHKKHK SSSS SS+E S+ S +KK+ +K G+
Sbjct: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
Query: 229 ---------------LQVRNSDRNQGLQGP--LTAEQKRGHGMKNHS----RSRSSSHSP 267
L + +R + + P L E R +HS +SR+ HSP
Sbjct: 307 SEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSP 366
Query: 268 PRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQR 326
+ S++ + S R RS RSRSP K +RET + +P +E +R
Sbjct: 367 EKRGSERKEGSSRSHGREERSRRSRSRSPGSYK-------QRETRKRAQRNPGEEQSRR 418
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/230 (22%), Positives = 85/230 (36%), Gaps = 22/230 (9%)
Query: 94 KYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREV 153
K F+K K S + S + S S S+ I RKK ++ K
Sbjct: 242 KKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSG 301
Query: 154 LNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKK 213
NN E+K+K KK++ ++ H + +H + R K
Sbjct: 302 HNNS------------DSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSK 349
Query: 214 MANS-SPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHAS 272
++S S S+ + + R S+R +G R HG + SR RS S SP +
Sbjct: 350 WSHSDSDKKSRTHKHSPEKRGSERKEG--------SSRSHGREERSR-RSRSRSPGSYKQ 400
Query: 273 KKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
+++ + A +S SRS K+ R G T + ++E
Sbjct: 401 RETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/263 (21%), Positives = 117/263 (44%), Gaps = 30/263 (11%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMS--LEKKEKKKKKEKKKKHKKHKHRSSSSDRSS 200
+ +E K R ++ K K +E ++ +++K+++K++E++K+ +K K R + DR
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 419
Query: 201 SEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS 260
++ +K + + R+ ++ + E+ R + +
Sbjct: 420 EREKDREKDKEKDREREREKEHE------KDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 261 RSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPK 320
S +PPR + + SR+RR R SRSPR SK K +RSPSP+
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK-------SSRSPSPR 526
Query: 321 KEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLD 380
+R ++ E++R + E RE ER +++ + D + +++LEK
Sbjct: 527 ------------SRNKKDKKREKERDHISER---RERERSTSMRKSSNDRDGKEKLEKNS 571
Query: 381 SRDGKFIHRMKLESASTSSLEDR 403
+ + H + +S+ + ++D+
Sbjct: 572 TSLKEKEHNKEPDSSVSKEVDDK 594
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/297 (20%), Positives = 103/297 (34%), Gaps = 44/297 (14%)
Query: 129 DMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKK 188
D KI I++ E + MK+++E E + K ++K +
Sbjct: 248 DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR 307
Query: 189 HKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQ 248
+ + S RSSS+ RSQ K
Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSK----------------------------------- 332
Query: 249 KRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNR 308
H ++H+RSRS R S R R+SRS RS S K K+
Sbjct: 333 ---HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS---RSHSRDKRKDTREKIKE 386
Query: 309 RETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK 368
+E + + ++E + R K + ER++ + K RE ER K H K
Sbjct: 387 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER---EKEHEK 443
Query: 369 DEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR 425
D ++E+ E+ ++ + +++ + R Y+ R S + + +R
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Score = 39.7 bits (91), Expect = 0.005
Identities = 47/238 (19%), Positives = 93/238 (39%), Gaps = 13/238 (5%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMY 74
+ ++ E+V + +++ E ER+K E ++E + + R++ + + K +E + + +
Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 441
Query: 75 QGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKI 134
+ E + +K ++++EK S P N+ S
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-------SRTPPRSYNASRRSRSSS 494
Query: 135 REDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSS 194
RE R+ + + +K K + S KK+KK++KE+ ++ + S
Sbjct: 495 RERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 195 SSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGH 252
+S R SS D + +K NS+ + K S P T E K H
Sbjct: 552 TSMRKSSNDRDGKEKLEK---NSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQH 606
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/263 (21%), Positives = 117/263 (44%), Gaps = 30/263 (11%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMS--LEKKEKKKKKEKKKKHKKHKHRSSSSDRSS 200
+ +E K R ++ K K +E ++ +++K+++K++E++K+ +K K R + DR
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 303
Query: 201 SEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS 260
++ +K + + R+ ++ + E+ R + +
Sbjct: 304 EREKDREKDKEKDREREREKEHE------KDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 261 RSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPK 320
S +PPR + + SR+RR R SRSPR SK K +RSPSP+
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK-------SSRSPSPR 410
Query: 321 KEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLD 380
+R ++ E++R + E RE ER +++ + D + +++LEK
Sbjct: 411 ------------SRNKKDKKREKERDHISER---RERERSTSMRKSSNDRDGKEKLEKNS 455
Query: 381 SRDGKFIHRMKLESASTSSLEDR 403
+ + H + +S+ + ++D+
Sbjct: 456 TSLKEKEHNKEPDSSVSKEVDDK 478
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/297 (20%), Positives = 103/297 (34%), Gaps = 44/297 (14%)
Query: 129 DMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKK 188
D KI I++ E + MK+++E E + K ++K +
Sbjct: 132 DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR 191
Query: 189 HKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQ 248
+ + S RSSS+ RSQ K
Sbjct: 192 SRSHTRSKSRSSSKSHSRRKRSQSK----------------------------------- 216
Query: 249 KRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNR 308
H ++H+RSRS R S R R+SRS RS S K K+
Sbjct: 217 ---HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS---RSHSRDKRKDTREKIKE 270
Query: 309 RETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK 368
+E + + ++E + R K + ER++ + K RE ER K H K
Sbjct: 271 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER---EKEHEK 327
Query: 369 DEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR 425
D ++E+ E+ ++ + +++ + R Y+ R S + + +R
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Score = 39.7 bits (91), Expect = 0.005
Identities = 47/238 (19%), Positives = 93/238 (39%), Gaps = 13/238 (5%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMY 74
+ ++ E+V + +++ E ER+K E ++E + + R++ + + K +E + + +
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 325
Query: 75 QGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKI 134
+ E + +K ++++EK S P N+ S
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-------SRTPPRSYNASRRSRSSS 378
Query: 135 REDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSS 194
RE R+ + + +K K + S KK+KK++KE+ ++ + S
Sbjct: 379 RERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 195 SSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGH 252
+S R SS D + +K NS+ + K S P T E K H
Sbjct: 436 TSMRKSSNDRDGKEKLEK---NSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQH 490
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 66.6 bits (161), Expect = 4e-11
Identities = 95/423 (22%), Positives = 188/423 (44%), Gaps = 59/423 (13%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRE----LREERAREEMQ----RYAEDVGAVKKK 66
Q LR E+ + Q+ E + +K +ELQ+E LREER + +Q +Y E+ +++
Sbjct: 1002 QLLRE-EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Query: 67 E------------EKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLL 114
E ++L+ Y+ + +E LL +K + +E+E C E L
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK---RRRQERERQCREEEELQ 1117
Query: 115 PGS---IFAPSGANSLLDMASKIREDPLF------IIRKKEEEKKREVLNNPVK-MKKIK 164
+ ++ + RE+ ++R++ E+++R+ L + ++++
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 165 ELLQMSLEKKEKKKKKEKKKKHKKHK--HRSSSSDRSSSEDEHSAGRSQKKMANSSPVL- 221
+ + L ++++K+++E+++++++ + R R ED+ S + Q + + V
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 222 SKVPGYG-----------LQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSP-PR 269
+KV G Q+R+ Q LQ L +Q+R + + H P
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
Query: 270 HASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHA 329
++ +EA RDR+S+ + R R K + +R+ + + ++E RR
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
Query: 330 PGYTRKLSAEEL---ERKRQEMMENAKWREEER-LNILK--RHAKDEEREQRLEKLDSRD 383
RK EEL E+ R+ + E + R +ER LK + + +EREQ+L + RD
Sbjct: 1358 --RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ--DRD 1413
Query: 384 GKF 386
KF
Sbjct: 1414 RKF 1416
Score = 65.9 bits (159), Expect = 7e-11
Identities = 71/370 (19%), Positives = 152/370 (41%), Gaps = 61/370 (16%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKL---------- 70
E++ K +Q + E EELQRE RE+R R+E +R + ++++EE+L
Sbjct: 897 EQLRKEQQLLQEEE---EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 71 ---DWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSL 127
+ Y+ + ++E LLG +K + +E+E E
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEK---RRRQEREKKYREE----------------- 993
Query: 128 LDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKK--IKELLQMSLEKKEKKKKKEKKKK 185
+++++ ++R++ E+++R+ + K +E Q+ E++EK++ +E++++
Sbjct: 994 ----EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
Query: 186 HKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLT 245
+++ + ++ E+ + R + + Q R + Q + L
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELER---------------QYRKEEELQQEEEQLL 1094
Query: 246 AEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSK 305
E+ + R R ++ RR + L R+ R + +
Sbjct: 1095 REEPEKR--RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Query: 306 VNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKR 365
+ R E + R +++ + +L EE E++RQE ++REEE L KR
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE--RERQYREEEELQRQKR 1210
Query: 366 HAKDEEREQR 375
+ + +QR
Sbjct: 1211 KQRYRDEDQR 1220
Score = 63.9 bits (154), Expect = 3e-10
Identities = 81/422 (19%), Positives = 173/422 (40%), Gaps = 54/422 (12%)
Query: 27 EQKHEAERKKIEELQRELREE---RAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNR 83
+++ E ++++ E R+L EE R R++ Q ++ +++ EK + + Q R
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ--RDRQRR 169
Query: 84 DEYLLGRPIDKYVFEKMEEKEA------GCSS-ETGLLPGSIFAPSGANSLLDMASKIRE 136
DE L + + +++ EE+ A C ET P LL++ K RE
Sbjct: 170 DEELWRQ---RQEWQEREERRAEEEQLQSCKGHETEEFPDE--EQLRRRELLELRRKGRE 224
Query: 137 ----------DPLF-------------IIRKKEEEKKREVLNNPVKMKKIKELLQMSLEK 173
D +F ++RK+EE+ + E ++++ +E L+ LE+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR-KLER 283
Query: 174 KEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRN 233
+E +++++++++ ++ R R E+ +++ + L+
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 234 SDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRS 293
+R + E++R ++ R + ++ RR + L R
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL----RREQQLRREQ 399
Query: 294 RSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMM---- 349
+ R +L + RRE R ++E + RH + ++ + L+R+++E
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
Query: 350 ---ENAKWREEERLNILKRHAKDEEREQ--RLEKLDSRDGKFIHRMKLESASTSSLEDRV 404
E + +E R LKR ++E RE+ +LE+ + R+ + +L E R+
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 405 KR 406
KR
Sbjct: 520 KR 521
Score = 58.9 bits (141), Expect = 8e-09
Identities = 73/415 (17%), Positives = 169/415 (40%), Gaps = 38/415 (9%)
Query: 5 DLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVK 64
+L ++ Q + + + + +K E ER+ E Q E RE++ R E Q + +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERR---EQQEERREQQERREQQEERREQQLRR 341
Query: 65 KKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGA 124
++EE+ + + R++ L ++ E +E E L
Sbjct: 342 EQEERREQQLRREQEEERREQQLRRE-------QEEERREQQLRREQQLR---------R 385
Query: 125 NSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKK 184
L ++R + +R++++ ++ + L ++++ ++L + E++ ++K +++++
Sbjct: 386 EQQLRREQQLRREQQ--LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 185 KHKKHKHRSSSSDRSSSEDE---HSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQ 241
+ + + + D E+E H R ++++ + L+ Q +
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 242 GPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRS-----RSP 296
++ + R R S++ R +RR + L R +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE-QEERREQLLKREEEKRLEQER 562
Query: 297 RPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELER-----KRQEMMEN 351
R +L + RR+ R +++ +R ++L EE+ER +R++ ++
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Query: 352 AKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
+ EE R +LK ++E R+Q+L + + + R+K E LE R+KR
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRR--EQQERREQRLKREE-EEERLEQRLKR 674
Score = 58.2 bits (139), Expect = 1e-08
Identities = 77/383 (20%), Positives = 157/383 (40%), Gaps = 16/383 (4%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMY 74
Q R E+ + +Q+ E+++ E Q E RE++ R E + E +++EE+ +
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 75 QGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKI 134
+ R++ L R + E+ +E E L L ++
Sbjct: 365 RREQEEERREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQL 419
Query: 135 REDPLFIIRKKEE--EKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHR 192
R + ++EE E+K E ++K+ +E + L+++E+ ++ E++++ ++ K
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 193 SSSSDRSS-SEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRG 251
R + E R Q++ + +++ + + LQ L +EQ+
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 252 HGMKNHSRSRSSSHSPPR-HASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRE 310
+ R ++ R ++ R L +R R +L + R E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 311 TGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDE 370
R + E +RR ++L EE E +R++ + ++ +EE R L+R + E
Sbjct: 600 QRLKREEVERLEQEERRE-----QRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-QQE 653
Query: 371 EREQRLEKLDSRDGKFIHRMKLE 393
REQRL K + + + R+K E
Sbjct: 654 RREQRL-KREEEEERLEQRLKRE 675
Score = 54.7 bits (130), Expect = 2e-07
Identities = 79/398 (19%), Positives = 164/398 (41%), Gaps = 48/398 (12%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGM 80
EK W+ ++ RK+ E+LQ E E + + E+Q E + ++++E + + +
Sbjct: 243 EKEWR--KRETVLRKEEEKLQEE--EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 81 VNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLF 140
R E L R ++ E+ EE+ + + RE L
Sbjct: 299 RLRREQQLRRKQEEERREQQEERRE------------------QQERREQQEERREQQL- 339
Query: 141 IIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSS 200
++E+E++RE ++ ++ +E + L ++++++++E++ + ++ R R
Sbjct: 340 ---RREQEERRE---QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 201 SEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS 260
R ++++ + + Q+R + + Q EQK +
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQ-----QLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 261 RSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK-LHNSKVNRRETGQTRSPSP 319
R ++ T E ++RR + L R R + L + RRE + R
Sbjct: 449 REQEERRDWLKREEET-ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Query: 320 KKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKR----HAKDEEREQR 375
++E +RR R+ E L+++ + + + +EE R +LKR + E REQR
Sbjct: 508 RREQEERREQR-LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 376 LEK-LDSRDGKFIHR------MKLESASTSSLEDRVKR 406
L++ + R + + R +L+ LE R+KR
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Score = 54.7 bits (130), Expect = 2e-07
Identities = 83/400 (20%), Positives = 159/400 (39%), Gaps = 64/400 (16%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGM 80
E+ + EQ+ E +++ Q+ RE++ R E Q E ++E++L Q
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ---LRREQQLRREQQLRREQ 417
Query: 81 VNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLF 140
R E L R ++ E+ E+E L + R D L
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQER------------------REQRLKREQEERRDWL- 458
Query: 141 IIRKKEEEKKREVLNNPVKMKKIKELLQ----MSLEKKEKKKKKEKKKKHKKHKHRSSSS 196
+++EE ++ E ++K+ +E + + LE++E+++++E++++ + +
Sbjct: 459 --KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 197 DRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKN 256
R ++E R Q+++ + Q+R + Q E+KR ++
Sbjct: 517 QRLKRQEEEE--RLQQRLRSEQ-----------QLRREQEERREQLLKREEEKR---LEQ 560
Query: 257 HSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRS 316
R + + RE +RR + L R +L +V R E + R
Sbjct: 561 ERREQRLKREQEERRDQLLKRE---EERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 317 PSPKKEVYQRRHAPGYTRKLSAEE-----LERKRQEMMENAKWREEERLNI---LKRHAK 368
K+E + + EE L R++QE E REEE + LKR +
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 369 DEEREQRL---------EKLDSRDGKFIHRMKLESASTSS 399
+E REQ L E++ SR K+ +++ E+ + S
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
Score = 52.8 bits (125), Expect = 6e-07
Identities = 82/384 (21%), Positives = 157/384 (40%), Gaps = 59/384 (15%)
Query: 13 HPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAED--VGAVKKKEE-- 68
H Q R + E++ K+EE +R ++ER ++++R E+ +K++EE
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Query: 69 ----KLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGA 124
+L Q R E LL R +K + ++ E+
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR-------------------- 566
Query: 125 NSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKK 184
L + R D L K+EEE++++ L ++ +E L+ L+++E ++ +++++
Sbjct: 567 ---LKREQEERRDQLL---KREEERRQQRLK-----REQEERLEQRLKREEVERLEQEER 615
Query: 185 KHKKHKHRSSSSDRS----SSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGL 240
+ ++ K +R SE++ + Q + ++ + R R +
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 241 QGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK 300
EQ+ + +R R S P +S EA +R + S R+ R +
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLES--EADARQSKVYSRPRKQEGQRRRQ 733
Query: 301 LHNSKVNRRET-----GQTRSPSPKKEVYQRRHAPGYTRKLSAEE-LERKRQEMMENAKW 354
K RRE+ + R+ ++E QRR +T + AEE ER RQ +
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRR---DFTWQWQAEEKSERGRQRLSARPPL 790
Query: 355 REEERLNILKRHAKDEEREQRLEK 378
RE+ +R + EER+QR ++
Sbjct: 791 REQR-----ERQLRAEERQQREQR 809
Score = 50.1 bits (118), Expect = 4e-06
Identities = 52/284 (18%), Positives = 111/284 (39%), Gaps = 7/284 (2%)
Query: 101 EEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKM 160
EEK A C + LL ++ E+P R+K +E++RE+ +
Sbjct: 97 EEKRARCDGKESLLQDRR-QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 161 KKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSS---SEDEHSAGRSQKKMANS 217
+K + L Q ++++++ +++++ ++ + R+ S E E Q +
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 218 SPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTR 277
+ K Q R +++ Q E ++ + + P R +
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 278 EAGSR-DRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTR--SPSPKKEVYQRRHAPGYTR 334
E + +R+ R+ + +L + RR+ + R ++E +RR R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 335 KLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEK 378
+ + +R+E + EE R L+R ++E REQ+L +
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Score = 48.1 bits (113), Expect = 1e-05
Identities = 77/413 (18%), Positives = 168/413 (40%), Gaps = 23/413 (5%)
Query: 15 QTLRNVEKVWKAEQ-KHEAERKKIEE-LQRELREERAREEMQRYAEDVGAVKKKEEKLDW 72
Q LR ++ + ++ K E E +++E+ L+RE EER +E+ ++ + K W
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
Query: 73 MYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMAS 132
+Q R + RP + + +E+E L A+
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ--EEERAHRQQQEEE 762
Query: 133 KIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKK---KEKKKKHKKH 189
+ R+ +++ E+ R+ L+ +++ +E + E+++++++ +E++K+ ++
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Query: 190 KHRSSSSDRSSSEDEHSAGRSQK--KMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAE 247
+ R + E+E R ++ ++ L + + + R+Q + L E
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE-DQERRRSQEQRRDQKWRWQLEEE 881
Query: 248 QKRGH-------GMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK 300
+KR ++ R ++ RE RR + R+ R +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE----KRRRQEQERQYREEEQLQ 937
Query: 301 LHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL 360
++ R E + R +++ + + +L EE E++R++ E K+REEE L
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-KYREEEEL 996
Query: 361 NILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQR 413
+ EERE+R + R + ++ E E+R KR + +R
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR-EEREKRRLQERER 1048
Score = 48.1 bits (113), Expect = 1e-05
Identities = 92/394 (23%), Positives = 159/394 (40%), Gaps = 52/394 (13%)
Query: 9 KKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEE 68
+KS + L E+ K ++ E +RK EE Q L +ER + ++R D K +EE
Sbjct: 1312 RKSQEEKQLLREEREEK-RRRQETDRKFREEEQ--LLQEREEQPLRRQERDR---KFREE 1365
Query: 69 KLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLL----PGSIFAPSGA 124
+L +Q G +E L R + F K EE++ C L
Sbjct: 1366 EL--RHQEQGRKFLEEEQRLRRQERERKFLK-EEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 125 NSLLDMASKIREDPLFIIRKKEEEKKREV-----LNNPVKMKKIKELLQMSLEKKEKKKK 179
S + K RE+ + R++ E K E K ++ ++LLQ E++ +++
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 180 KEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQG 239
+++K ++ + R DR E E + ++K L R Q
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL-------------HRQQR 1529
Query: 240 LQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPS 299
+ L EQ+ ++ R + R K E ++R + L R+ R R
Sbjct: 1530 QRKFLQEEQQ----LRRQERGQQRRQDRDR---KFREEEQLRQEREEQQLSRQERD-RKF 1581
Query: 300 KLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEER 359
+L KV R+E Q R ++ +R+ R +E +RK +E + + REE++
Sbjct: 1582 RLEEQKVRRQE--QERKFMEDEQQLRRQEGQQQLR----QERDRKFREDEQLLQEREEQQ 1635
Query: 360 LNILKRHAKDEEREQRLEKLD-------SRDGKF 386
L+ +R K E E +L + + RD KF
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Score = 47.8 bits (112), Expect = 2e-05
Identities = 71/373 (19%), Positives = 152/373 (40%), Gaps = 53/373 (14%)
Query: 28 QKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYL 87
++ E ERK +EE +++LR+ER R ++ E+ ++++EE+ + + ++ L
Sbjct: 1440 RRQERERKFLEE-EQQLRQERHR----KFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 88 LGRPIDKYVFE---KMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRK 144
+ D+ E + +E E E L K ++ + R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQ-----------QRQRKFLQEEQQLRRQ 1543
Query: 145 KEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDE 204
+ +++R+ + K ++ ++L Q E++ ++++++K + ++ K R +R EDE
Sbjct: 1544 ERGQQRRQ--DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 205 HSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSS 264
R + + Q+R + + +++ + R R
Sbjct: 1602 QQLRRQEGQQ---------------QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 265 HSPPR-HASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRR---ETGQTRSPSPK 320
P+ ++ + RDR+ R + + +L + +R+ E Q R +
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 321 KEVYQRRHAPGYTRKLSAEELERK-------RQEMMENAKWREEERLNILKRHAKDEERE 373
++ Q ++L +ELERK RQE + R+E IL+ ERE
Sbjct: 1707 RKFLQEE------QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 374 QRLEKLDSRDGKF 386
++ + RD KF
Sbjct: 1761 EQQLRRQERDRKF 1773
Score = 45.8 bits (107), Expect = 7e-05
Identities = 85/423 (20%), Positives = 167/423 (39%), Gaps = 59/423 (13%)
Query: 15 QTLRNVEKVWKAEQKH----EAERKKIEELQRELREERAR----EEMQRYAEDVGAVKKK 66
Q LR E+ K ++ E ERK +EE Q+ R++R R EE Q ++ G +++
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 67 EEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGS--IFAPSGA 124
+ + + R+E L R F E+K E + + G
Sbjct: 1552 DRDRKFREEEQLRQ-EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 125 NSLL-DMASKIREDPLFIIRKKEE-----EKKREVLNNPVKMKKIKELLQMSLEKKEKKK 178
L + K RED + ++E+ E+ R+ L ++++ + Q+ ++ K +
Sbjct: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 179 KKEKK-KKHKKHKHRSSSSDRSSSEDEHSAGRSQK--KMANSSPVLSKVPGYGLQVRNSD 235
++E+ ++ ++ + R DR E+E R ++ K L + L+ + +
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE---LERKFRE 1727
Query: 236 RNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRS 295
Q Q EQ++ + + + P ++ R+ R R R+ R
Sbjct: 1728 EEQLRQ---ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 296 PRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYT---RKLSAEELERK-RQEM--- 348
+ + S RE Q R ++++ ++ Y +L EE E++ RQE
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 349 ---------------MENAKWREEE-----------RLNILKRHAKDEEREQRLEKLDSR 382
E W+EEE R ++R K+E+R +++ ++ S+
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Query: 383 DGK 385
+GK
Sbjct: 1905 EGK 1907
Score = 39.7 bits (91), Expect = 0.005
Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 13/170 (7%)
Query: 246 AEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSK 305
AE+++ K H R R G +++ + RR R R + K
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ---RRERQDRVFQEEEEK 244
Query: 306 -------VNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEE 358
V R+E + + P+++ + + RKL +EL R+RQE E + +
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQ-RELQEEEEQLRKLERQELRRERQE--EEQQQQRLR 301
Query: 359 RLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNI 408
R L+R ++E REQ+ E+ + ++ + + E E+R ++ +
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Score = 33.9 bits (76), Expect = 0.29
Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Query: 21 EKVWKAEQK--HEAERKKIEELQRELREE---RAREEMQRYAEDVGAVKKKEEKLDWMYQ 75
EK + EQ+ E E+K+ +E +R+LREE R ++E QR+ + VG +K +E K
Sbjct: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQ-VGEIKSQEGKGHGRLL 1913
Query: 76 GPGGMVNRDEYLLGRPIDKYVFEKMEE 102
PG + P+ +Y+ E+ +
Sbjct: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
Score = 30.8 bits (68), Expect = 2.4
Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 9/137 (6%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRY--AEDVGAVKKK---EEKLDWMYQ 75
E+ + +Q+ R + E+LQ E +E+R R+E R AE+ A ++K EE+ W +
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 76 GPGGMVNRDEYLLGRPIDKYVFEKMEEKEAG-CSSETGLLPGSIFAPSGANSLLDMASKI 134
R+ L I + E+ ++ G S+ G G + P G + + +
Sbjct: 1869 EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEP-GTHQFASV--PV 1925
Query: 135 REDPLFIIRKKEEEKKR 151
R PL+ +++ + R
Sbjct: 1926 RSSPLYEYIQEQRSQYR 1942
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 65.5 bits (158), Expect = 9e-11
Identities = 71/299 (23%), Positives = 128/299 (42%), Gaps = 31/299 (10%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSS-- 200
RK E+EKK + + K + I+ + + K K KK+ K K K K +S S +R S
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 201 SEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQK---------RG 251
+ +E RS+ K + V K + ++ +R++ + E K +
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 252 HGMKNHSRSRSSSHSPPRHASKKSTRE-AGSRDR----RSRSLGR-RSRSPRPSKLHNSK 305
+ SRSR + +H+ TRE + SRDR RSR+ R RSRS + +
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 306 VNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKR 365
RR G++RS +RR PG +R +R+R+ + REE + +
Sbjct: 598 YRRR--GRSRS-------RERRTPPGRSR-----SKDRRRRRRDSRSSEREESQSRNKDK 643
Query: 366 HAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMK 424
+ E + ++ + + + + ++S +S E + R+ + + + N +K
Sbjct: 644 YRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELK 702
Score = 59.7 bits (143), Expect = 5e-09
Identities = 64/286 (22%), Positives = 109/286 (38%), Gaps = 23/286 (8%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSD--RSSS 201
K E + +E +PV++K+ +++ + +K EK+KK K HK S D R+S
Sbjct: 385 KSELNEIKENQRSPVRVKE-RKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE 443
Query: 202 EDE----------HSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRG 251
+D+ S RS+ K + S + R R++G E+++
Sbjct: 444 KDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ 503
Query: 252 HGMKNHSRSRSSSHSPPRHASKKSTR----EAGSRDRRSRSLGRRSRSPRPSKLHNSKVN 307
K + RS S + KS ++ +DRR++S R + +NS+
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563
Query: 308 RRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHA 367
R + RS + + R R S E + QE + R ER R
Sbjct: 564 ERSRSRDRSRRVRSRTHDR------DRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR 617
Query: 368 KDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQR 413
+ R +R + S + R K + + S K N S +R
Sbjct: 618 SKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKR 663
Score = 50.4 bits (119), Expect = 3e-06
Identities = 62/257 (24%), Positives = 99/257 (38%), Gaps = 37/257 (14%)
Query: 173 KKEKKKKKEKKKKHKKHKHRSSSSDRS-SSEDEHSAGRSQKKMANSSPVLSKVPGYGLQV 231
KK KKK ++ +KHKK K + S +S SSE E +Q + + +P +
Sbjct: 228 KKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLM 287
Query: 232 RNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPP---------RHASKKSTREAGSR 282
R S P A++K KN R R +PP R +S R+ R
Sbjct: 288 RKS--------PPKADEKE---RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGR 336
Query: 283 -------DRRSRSLGRRSRSPRP-------SKLHNSKVNRRETGQTRSPSPKKEVYQRRH 328
RSRS R RS P + +V+ E S E+ + +
Sbjct: 337 GPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQR 396
Query: 329 APGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIH 388
+P R + + + N K +E+++ K ++K+ + + EK D K
Sbjct: 397 SP--VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKK 454
Query: 389 RMKLESASTSSLEDRVK 405
R K +S S S + + K
Sbjct: 455 RAKSKSRSKSKEKSKSK 471
Score = 45.1 bits (105), Expect = 1e-04
Identities = 44/180 (24%), Positives = 63/180 (35%), Gaps = 51/180 (28%)
Query: 180 KEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQG 239
K K KK +K +H+SSSS SSS D S+ SQ +S
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSE------------------- 220
Query: 240 LQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPS 299
+A +++ K R S H + KKS + A S + + RP
Sbjct: 221 -----SATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPE 275
Query: 300 KLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEER 359
++ P P+ R+ P A+E ERK +E RE ER
Sbjct: 276 EI--------------PPIPENRFLMRKSPP------KADEKERKNRE-------RERER 308
Score = 30.4 bits (67), Expect = 3.2
Identities = 40/178 (22%), Positives = 71/178 (39%), Gaps = 8/178 (4%)
Query: 30 HEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLG 89
H+ +R + +E R +E R R E + K D + + E
Sbjct: 580 HDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK-DRRRRRRDSRSSEREESQS 638
Query: 90 RPIDKYVFE--KMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEE 147
R DKY + K ++ SE + S S NS A + + P I++ +
Sbjct: 639 RNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADR-DQSPFSKIKQSSQ 697
Query: 148 EKKREVLNNPVKMKKIKELLQMSLEKKEKKKK-KEKKKKHKKHKHRSSSSDRSSSEDE 204
+ + L + + K E ++ S+EK+ +K K +E H+K+K S + ED+
Sbjct: 698 DNE---LKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 63.5 bits (153), Expect = 3e-10
Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 11/156 (7%)
Query: 167 LQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSS-EDEHSAGRSQKKMANSSPVLSKVP 225
L S E+ KKK ++ + K S SS RSSS S RS+ + ++SS S+
Sbjct: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRR 285
R R++G + ++ RG SSS SP R+ + +R + S DR+
Sbjct: 245 S-----RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299
Query: 286 SRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKK 321
RR+RS P + H S +G +RS S KK
Sbjct: 300 K----RRTRSRSPERRHRSSSGSSHSG-SRSSSKKK 330
Score = 42.4 bits (98), Expect = 8e-04
Identities = 49/205 (23%), Positives = 83/205 (40%), Gaps = 25/205 (12%)
Query: 142 IRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSS 201
I ++E + + + K + K + S+ K+ + K+ E +++ + D
Sbjct: 115 IEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDED-- 172
Query: 202 EDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSR 261
EDE A S+ + S S + R+ R+ + + ++ SRSR
Sbjct: 173 EDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSR 232
Query: 262 --SSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRP----------------SKLHN 303
SSS S R +S++ +R GS+ R S R S SPR S+ +
Sbjct: 233 SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Query: 304 SKVNRRETGQTRSPSPKKEVYQRRH 328
S R+ +TRS SP +RRH
Sbjct: 293 SSSGDRKKRRTRSRSP-----ERRH 312
Score = 42.4 bits (98), Expect = 8e-04
Identities = 52/216 (24%), Positives = 83/216 (38%), Gaps = 29/216 (13%)
Query: 176 KKKKKEKKKKH------KKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGL 229
+KKKK + K K+ + + S + +++ S + + LSK Y L
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSK---YNL 185
Query: 230 QV-RNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRS 288
D N+ + + R ++ SRS S S S R S+ +R + S RSRS
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSS--RSRSRSRSRSSSSSQSRSRS 243
Query: 289 LGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEM 348
R R SK +S + R S SP+K Y+ S+ E RKR
Sbjct: 244 SSRERSRSRGSKSRSSSRSHR-----GSSSPRKR--------SYSSSSSSPERNRKRSRS 290
Query: 349 MENAKWREEERLNILKRHAKDEEREQRLEKLDSRDG 384
++ ++R + ++ ER R S G
Sbjct: 291 RSSSSGDRKKR----RTRSRSPERRHRSSSGSSHSG 322
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 60.8 bits (146), Expect = 2e-09
Identities = 70/270 (25%), Positives = 113/270 (41%), Gaps = 51/270 (18%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
+K+ + + +E + KK K +++ EK + K KE+KK K S S+
Sbjct: 181 KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSK 240
Query: 203 DEHSAGRSQKKMANS-SPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHS--- 258
RSQ+K+ + SP KV ++ ++ +++ + + R G K+ S
Sbjct: 241 SPTLRRRSQEKIGKARSPTDDKVK---IEDKSKSKDRKKSPIINESRSRDRGKKSRSPVD 297
Query: 259 --------RSRSSSH---------------SPPRHASKKSTREAGSRDRRSRSLGRRSRS 295
RSRS SP + AS + SR R RS RRS S
Sbjct: 298 LRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSR-RPGRSPKRRSLS 356
Query: 296 PRP-SKLHNSK---VNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMEN 351
P+P K S+ +N R + Q++SPS R +PG R+ + LERKR+E
Sbjct: 357 PKPRDKSRRSRSPLLNDRRSKQSKSPS-------RTLSPG--RRAKSRSLERKRRE---- 403
Query: 352 AKWREEERLNILKRHAKDEEREQRLEKLDS 381
E RL+ + +D+ +R D+
Sbjct: 404 ---PERRRLSSPRTRPRDDILSRRERSKDA 430
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/280 (22%), Positives = 118/280 (42%), Gaps = 50/280 (17%)
Query: 141 IIRKKEEEKKREVLNNPVKMK-KIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRS 199
II + + + +PV ++ K K+ S E+K K+ + +K+KK K + +SS +
Sbjct: 279 IINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKE 338
Query: 200 SSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSR 259
+ GRS K+ + L + D+++ + PL +++ S+
Sbjct: 339 NRSPSRRPGRSPKRRS-------------LSPKPRDKSRRSRSPLLNDRR-----SKQSK 380
Query: 260 SRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSK-------VNRRETG 312
S S + SP R A +SRSL R+ R P +L + + ++RRE
Sbjct: 381 SPSRTLSPGRRA-------------KSRSLERKRREPERRRLSSPRTRPRDDILSRRERS 427
Query: 313 QTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEER----LNILKRHAK 368
+ SP + RR + R+ S L R R + R +R + L+R ++
Sbjct: 428 KDASPINRWSP-TRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSR 486
Query: 369 DEEREQRLEKLDSRDGKFI------HRMKLESASTSSLED 402
+R + ++ KF +++ ES+S +LED
Sbjct: 487 SRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLED 526
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/264 (20%), Positives = 108/264 (40%), Gaps = 22/264 (8%)
Query: 142 IRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRS-- 199
I ++ E + N K K+ S KK K +E K K KHKH+ R
Sbjct: 24 INEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEI 83
Query: 200 -SSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKR-GHGMKNH 257
+ D+ +++ + +L + ++ N+ ++G + + G ++
Sbjct: 84 IDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESG 143
Query: 258 SRSRSSSHSPPRHASKKSTREAGSRDR--------------RSRSLGR-RSRSPRPSKLH 302
S H R+ ++ STR + ++ + +SRS R R RS +
Sbjct: 144 SEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKG 203
Query: 303 NSKVNRRETGQTRSPSPK--KEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL 360
++ + +T +++S K K +R + RK + L R+ QE + A+ ++++
Sbjct: 204 GIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKV 263
Query: 361 NIL-KRHAKDEEREQRLEKLDSRD 383
I K +KD ++ + + SRD
Sbjct: 264 KIEDKSKSKDRKKSPIINESRSRD 287
Score = 38.9 bits (89), Expect = 0.009
Identities = 64/370 (17%), Positives = 131/370 (35%), Gaps = 36/370 (9%)
Query: 18 RNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGP 77
R+ +K K KH+ + EE + + + + + + + E + A K+ P
Sbjct: 42 RHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEG-------MSP 94
Query: 78 GGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETG--LLPGSIFAPSGANSLLDMASKIR 135
D+ L E +E++ A +E L+ G + SG +L
Sbjct: 95 AKRTKLDDLAL--------LEDLEKQRALIKAELDNELMEGKV--QSGMGLILQGYESGS 144
Query: 136 EDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSS 195
E+ I K + ++ K K EL+ + K++ K + K++ + + S
Sbjct: 145 EEEGEIHEKARNGNRSSTRSSSTKGKL--ELVDNKITTKKRSKSRSKERTRHRSDKKKSK 202
Query: 196 SDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMK 255
+++ + +S+++ + SP R+ ++Q + ++R
Sbjct: 203 GGIEIVKEKTTRSKSKERKKSKSP----------SKRSKSQDQARKSKSPTLRRRSQEKI 252
Query: 256 NHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTR 315
+RS + SK R+ SRS R +S P L +RR + R
Sbjct: 253 GKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKER 312
Query: 316 SPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQR 375
+ +++ ++ S+ + R + R L +D+ R R
Sbjct: 313 KSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRS-----LSPKPRDKSRRSR 367
Query: 376 LEKLDSRDGK 385
L+ R K
Sbjct: 368 SPLLNDRRSK 377
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 60.8 bits (146), Expect = 2e-09
Identities = 68/300 (22%), Positives = 125/300 (41%), Gaps = 49/300 (16%)
Query: 24 WKAEQKHEAERKKIEELQREL---REERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGM 80
W+A + E E + + + EL EE EE Q E+ E++ D
Sbjct: 761 WEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEE------SEDEEDTQ-----SS 809
Query: 81 VNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLF 140
+ + +L PI + + E K + S E +K+RE L
Sbjct: 810 KSEEHHLYSNPIKEEMTESKFSKYSEMSEEK-------------------RAKLREIELK 850
Query: 141 IIRKKEEEKKREVLNNPVK--MKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDR 198
+++ ++E + + P + ++++ L+++++K+ + ++++ KK K + S +
Sbjct: 851 VMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSK 910
Query: 199 SSSE-DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNH 257
E DE + R ++K +S+ G +V++ + + +R H K
Sbjct: 911 DKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSP----KSERSERSERSH--KES 964
Query: 258 SRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSP 317
SRSRSS PR SKK+ R RS RSRSP+ K ++ Q+RSP
Sbjct: 965 SRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPK-------KSGKKSRSQSRSP 1017
Score = 43.9 bits (102), Expect = 3e-04
Identities = 57/259 (22%), Positives = 104/259 (40%), Gaps = 23/259 (8%)
Query: 27 EQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEY 86
+Q E+E ++ + + E +E + + + + KEE + + M
Sbjct: 783 DQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRA 842
Query: 87 LLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKE 146
L R I+ V + +E E+G + PG F + R+ L ++KE
Sbjct: 843 KL-REIELKVMKFQDELESGKRPKK---PGQSFQ--------EQVEHYRDKLLQREKEKE 890
Query: 147 EEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHS 206
E++RE + KK KE L+ + K++K + +K +K +H +S S SS
Sbjct: 891 LERERE------RDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRV 944
Query: 207 AGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRG-HGMKNHSRSRSSSH 265
S K + S + R+ ++ ++ + KR G + RSR S
Sbjct: 945 KSPSPKSERSERSERS----HKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRS 1000
Query: 266 SPPRHASKKSTREAGSRDR 284
P+ + KKS ++ S R
Sbjct: 1001 RSPKKSGKKSRSQSRSPHR 1019
Score = 43.9 bits (102), Expect = 3e-04
Identities = 42/221 (19%), Positives = 90/221 (40%), Gaps = 17/221 (7%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
+ + ++ + +NP+K + + E E+K+ K ++ + K K +D
Sbjct: 807 QSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKF----------QD 856
Query: 204 EHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
E +G+ KK S +V Y ++ ++ + L+ ++K +++ S+ +
Sbjct: 857 ELESGKRPKKPGQSFQ--EQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKE 914
Query: 264 SHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRP--SKLHNSKVNRRETGQTRS---PS 318
++ R + S S GRR +SP P + S+ + +E+ ++RS S
Sbjct: 915 KDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDS 974
Query: 319 PKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEER 359
P+ + + +P +R R R K R + R
Sbjct: 975 PRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSR 1015
Score = 31.2 bits (69), Expect = 1.9
Identities = 48/242 (19%), Positives = 87/242 (35%), Gaps = 30/242 (12%)
Query: 195 SSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGL-------QVRNSDR--------NQG 239
+S ++ S D HS+G S M S P S +P RN +Q
Sbjct: 12 ASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPHQN 71
Query: 240 LQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSL-------GRR 292
L PL + + + S ++ + + KK E + + L G +
Sbjct: 72 LSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNK 131
Query: 293 SRSPRPSKLHNSKVNRRETGQTRSP--SPKKEVYQRRHAPGYT---RKLSAEELERKRQE 347
++ + N+ ET + R P +++ P + R S +E K+
Sbjct: 132 VKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPP 191
Query: 348 MMENAKWREEERLNILKRHAK--DEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVK 405
+ + K +++ L + K K EER++R K R +F S++ +
Sbjct: 192 LKKGEKEKKKSNLELFKEELKQIQEERDER-HKTKGRLSRFEPPQSDSDGQRRSMDAPSR 250
Query: 406 RN 407
RN
Sbjct: 251 RN 252
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 59.7 bits (143), Expect = 5e-09
Identities = 57/267 (21%), Positives = 105/267 (39%), Gaps = 35/267 (13%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQ-MSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSS 201
R + E+KR+ N K + + E K+K KK K ++H +H S +
Sbjct: 44 RSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN 103
Query: 202 EDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSR 261
E+ R ++K SS +G + ++R H ++ R +
Sbjct: 104 SSENGEDRHKRKERKSS-------------------RGRSHSRSRSRERRHRSRSRERKK 144
Query: 262 SSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRS-PRPSKLHNSKVNRRETGQTRSPSPK 320
S S S R S+ +RE RSR RR RS R H + R ++RS K
Sbjct: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRK 204
Query: 321 KEVYQRRH----------APGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDE 370
K + + R P + + +A + + +E AK +E+R ++ ++
Sbjct: 205 KRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR----EKEMVEK 260
Query: 371 EREQRLEKLDSRDGKFIHRMKLESAST 397
+++Q + + G ++ L ++ T
Sbjct: 261 QKQQEIAAAAATGGSVLNVAALLASGT 287
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/208 (24%), Positives = 77/208 (37%), Gaps = 21/208 (10%)
Query: 172 EKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQV 231
+KKE+ + + K H RS S R + GR + + S G +
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE--------GRRH 73
Query: 232 RNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR 291
+ D++ K K R SS + RH K+ G RSRS R
Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 292 RSRS-PRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMME 350
R RS R K S+ R+ ++RS KK +R S E R R
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKK-----------SRSRSRERKRRIRSRSRS 182
Query: 351 NAKWREEERLNILKRHAKDEEREQRLEK 378
++ R R R ++ +R++R+EK
Sbjct: 183 RSRHRHRTRSRSRTR-SRSRDRKKRIEK 209
Score = 48.5 bits (114), Expect = 1e-05
Identities = 52/222 (23%), Positives = 86/222 (38%), Gaps = 26/222 (11%)
Query: 193 SSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKR-- 250
+S ++R E ++ KK S +S R S + + E+KR
Sbjct: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSP--------RASKHHYSRSRSRSRERKRKS 54
Query: 251 -GHGMKNHSRSRSSS---HSPPRHASKKSTREAGSRDRRSRSLGRR--SRSPRPSKLHNS 304
G K+ SRSRS H +SKK E + S GR + S H
Sbjct: 55 DNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR 114
Query: 305 KVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILK 364
K + G++ S S +E RRH + + R+R++ ++ R++ R
Sbjct: 115 KERKSSRGRSHSRSRSRE---RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR----- 166
Query: 365 RHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
++ ER++R+ + HR + S + S DR KR
Sbjct: 167 --SRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206
Score = 38.5 bits (88), Expect = 0.012
Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 17/160 (10%)
Query: 256 NHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTR 315
++SRSRS S R +KS E R RSRS + R SK +SK ++ E +
Sbjct: 39 HYSRSRSRS----RERKRKSDNEG--RKHRSRSRSKEGRR-HESKDKSSKKHKSEEHNDK 91
Query: 316 SPSPKKEVYQRRHAPGYTRKLSAEELE-RKRQEMMENAKWREEERLNILKRHAKDEEREQ 374
S K G R S+E E R +++ ++++ R R +R + RE+
Sbjct: 92 EHSSDK---------GRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER 142
Query: 375 RLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRT 414
+ + SR+ K E + S KR I S R+
Sbjct: 143 KKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 58.9 bits (141), Expect = 8e-09
Identities = 54/187 (28%), Positives = 81/187 (43%), Gaps = 21/187 (11%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEK-------KEKKKKKEKKKKHKKHKHRSSS 195
R+ EEEK+ V + K +++ S K + + K K+K+K K+ + S S
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS 366
Query: 196 SDRSSSEDEHSAGRSQKK--MANSSPVLSKVPGYGLQVRNSDRNQGLQ---GPLTAEQKR 250
RS S+ E S R K+ A SS K Q R+ R+ + + Q+
Sbjct: 367 RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQRE 426
Query: 251 GHG--------MKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR-RSRSPRPSKL 301
G G + SRSRS+S S P S+ +R + RSRS R RS S PS+
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
Query: 302 HNSKVNR 308
+ +R
Sbjct: 487 RSRSHSR 493
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/288 (22%), Positives = 109/288 (37%), Gaps = 28/288 (9%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
K K R + + + S + +K+K + K+ + + S+ RS S+D
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 204 E--------HSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMK 255
+ + G+ + + + SK + R + +G +++K +
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 256 NHSRSRSSSHSPPRHASK--------KSTREAGSRDRRSRSLGRRSR---SPRPSKLHNS 304
+ SRS+ S S R SK K +RE RSRS RSR S R SK +S
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 305 KVNRRE-TGQTRSPSPKKEV-YQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNI 362
K ++E T +++S SP + V +R HA +E +R+ + ENA +E R
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKEREHA-------KSESSQREGRGESENAGTNQETRSRS 444
Query: 363 LKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYS 410
K R K S S S R + +S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 52.4 bits (124), Expect = 8e-07
Identities = 59/229 (25%), Positives = 91/229 (39%), Gaps = 28/229 (12%)
Query: 173 KKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDE-HSAGRSQKKMANS-SPVLSKVPGYGLQ 230
+K + + K H K + RS S RS S+ S RS+ K S SP K
Sbjct: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKS------ 255
Query: 231 VRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLG 290
R+ + G + +Q N + + S SP RH SK +R SRS
Sbjct: 256 -RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR--------SRSQE 306
Query: 291 RRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMME 350
RR + + + + Q+RS S K + R +R S + +RK ++
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR-----SRSRSKSKDKRKGRK--- 358
Query: 351 NAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSS 399
+ REE R R +K E +R K DS+ G + K ++ + S
Sbjct: 359 --RSREESRSRSRSR-SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 7/135 (5%)
Query: 248 QKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR-RSRSPRPSKLHNSKV 306
++R ++ S SRS S S RH+ K +R S+ S+S R RS S SK +
Sbjct: 180 RRRRSYSRSRSHSRSRSRS--RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 307 NRRETGQTRSPSPKKEVYQ-RRHAPGYTRKLSAEELERKRQ--EMMENAKWREEERLNIL 363
+R + + +S SP KE + R H+ G +R S ++ E K Q + + K R R +
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR-HKS 296
Query: 364 KRHAKDEEREQRLEK 378
K ++ +E+R+E+
Sbjct: 297 KSKSRSRSQERRVEE 311
Score = 46.2 bits (108), Expect = 6e-05
Identities = 73/325 (22%), Positives = 122/325 (37%), Gaps = 72/325 (22%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
K+ EK N K++ +++ + + + + + + R S S SS+
Sbjct: 154 KRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
Query: 204 EHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
HS RS+ + + S S+ R+ R++ + + K K+ SRS S+
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRS-------RSQSRSRSKKEKSRSPSKE----KSRSRSHSA 262
Query: 264 -------------------------SHSPPRHASKKSTR--------------------- 277
S SP RH SK +R
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRS 322
Query: 278 -EAGSRDRRSRSL---GRRSRSPRPSKLHNSKVNR-RETGQTRSPSPKKEVYQRRHAPGY 332
E R RSRS G RSRS SK + + R R ++RS S + +R G
Sbjct: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
Query: 333 TRKLSAEELERKRQEMMENAKWREEER-LNILKRHAKDE--EREQRLEKLDSRDGKFIHR 389
R A ++K++E + ++ R R ++ + HAK E +RE R E ++ +
Sbjct: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ---- 438
Query: 390 MKLESASTSSLEDRVKRNIYSLQRT 414
E+ S S + K N+ S R+
Sbjct: 439 ---ETRSRSRSNSKSKPNLPSESRS 460
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.9 bits (141), Expect = 8e-09
Identities = 74/401 (18%), Positives = 167/401 (41%), Gaps = 69/401 (17%)
Query: 12 WHPQTLRNVEKVWKAEQKHEAERKKIEELQRELR--EERAREEMQRYAEDVGAVKKKEEK 69
W+ + EK+W+ E+K + +KI+E + ++R EE+ RE+ ++ + +KEEK
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 70 LDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLD 129
+ R E ++ EKM +E + +
Sbjct: 351 M-----------RRQEEMMWEK-----EEKMRRQE--------------------EMMWE 374
Query: 130 MASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKH 189
K+R + K EEK RE+ + +KI+E EK+++++K +++K ++
Sbjct: 375 KEEKMRRQEEMMWEK--EEKIRELEEKMHEQEKIRE----QEEKRQEEEKIREQEKRQEQ 428
Query: 190 KHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQK 249
+ + + E E +KKM + + ++R ++ Q Q + +++
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE----KIREEEKRQE-QEEMWRQEE 483
Query: 250 RGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRR 309
+ H + R + H +K + ++ + R + R + K+ + R
Sbjct: 484 KIHEQEEIWRQKEKMHE-QEEKIRKQEEKVWRQEEKIREQEEKIRE-QEEKMWRQEEKIR 541
Query: 310 ETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERL-----NILK 364
E ++E+++ K+ EE KRQE E+ WR+EE++ + +
Sbjct: 542 E---------QEEMWREEEKMHEQEKIWEEE---KRQE-QEDKMWRQEEKIREQEEKVWR 588
Query: 365 RHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVK 405
+ K E+E++ ++ + + K +++ + E++++
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Score = 45.1 bits (105), Expect = 1e-04
Identities = 46/207 (22%), Positives = 99/207 (47%), Gaps = 40/207 (19%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQREL--REERAREEMQRYAEDVGAVKKKEEKLDW 72
+ + E++W+ ++K + +KI + + ++ +EE+ RE+ ++ E + ++EEK+
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI-- 540
Query: 73 MYQGPGGMVNRDEYLLGRPIDK-YVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMA 131
R++ + R +K + EK+ E+E E + +
Sbjct: 541 ----------REQEEMWREEEKMHEQEKIWEEEKRQEQE--------------DKMWRQE 576
Query: 132 SKIREDPLFIIRK----KEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHK 187
KIRE + R+ +E+E+KR+ KM K +E ++ E++EK +++E+K + +
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIR---EQEEKIQEQEEKIREQ 631
Query: 188 KHKHRSSSSDRSSSEDEHSAGRSQKKM 214
+ K R + + E E G ++KM
Sbjct: 632 EEKIR--EQEEMTQEQEEKMGEQEEKM 656
Score = 43.1 bits (100), Expect = 5e-04
Identities = 40/211 (18%), Positives = 90/211 (42%), Gaps = 27/211 (12%)
Query: 9 KKSWHPQT-LRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKE 67
+K W + +R E++W+ E+K + K EE +R+ +E++ + ++ E V ++E
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 68 EKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSL 127
EK I + ++ E++E E + +
Sbjct: 591 EK----------------------IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 128 LDMASKIREDPLFIIRKKEE--EKKREVLNNPVKMKKIKELLQMSLEK--KEKKKKKEKK 183
+ KIRE ++E+ E++ ++ KM++ +E + EK +++KK +E++
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 184 KKHKKHKHRSSSSDRSSSEDEHSAGRSQKKM 214
+K ++ + + E E ++KM
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Score = 42.4 bits (98), Expect = 8e-04
Identities = 38/175 (21%), Positives = 83/175 (47%), Gaps = 33/175 (18%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELR--EERAREEMQRYAEDVGAVKKKEEKLDWMYQGPG 78
EK+WK E+K + +KI+E + ++R EE+ RE+ + E + ++EEK M +
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK---MCEQEE 661
Query: 79 GMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDP 138
M ++E + + EK+ E+E + + KIRE
Sbjct: 662 KMQEQEETMWRQE------EKIREQE--------------------KKIREQEEKIREQE 695
Query: 139 LFIIRKKEE--EKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKH 191
+ ++E+ E++ ++ KM++ +E ++ EK +++ + ++++ K +H
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 40.4 bits (93), Expect = 0.003
Identities = 62/359 (17%), Positives = 144/359 (40%), Gaps = 47/359 (13%)
Query: 22 KVWKAEQKHEAERKKIEELQREL-REERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGM 80
K+W+ E+K + +KI E ++++ R+E E ++ E+ K++E++ W +
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE---KRQEQEEMWRQEEK--- 484
Query: 81 VNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLF 140
++ E + + EKM E+E + + + + KIRE
Sbjct: 485 IHEQEEIWRQK------EKMHEQEEKIRKQEEKVWRQ------EEKIREQEEKIREQEEK 532
Query: 141 IIRKKEEEKKREVL-NNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRS 199
+ R++E+ +++E + KM + +++ + ++++ K +++K ++ + + +
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 200 SSEDEHSAGRSQKKMANSSPVL----SKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMK 255
E E ++KM + K+ ++R + Q +T EQ+ G +
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 256 NHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTR 315
+K + + ++ R+ K+ + RE Q
Sbjct: 653 E----------------EKMCEQEEKMQEQEETMWRQEE-----KIREQEKKIRE--QEE 689
Query: 316 SPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQ 374
++E+ Q + + ++ E E K QE E + +EE+ R + EE+ Q
Sbjct: 690 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 58.9 bits (141), Expect = 8e-09
Identities = 63/242 (26%), Positives = 97/242 (40%), Gaps = 38/242 (15%)
Query: 131 ASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHK 190
A KI E P + P+ ++K + S + K+ +++EK+KK KKHK
Sbjct: 703 AGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHK 762
Query: 191 HRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKR 250
RS + RS S HS+ +S+ + + S +P VR S
Sbjct: 763 KRSRT--RSRSPKYHSSSKSRSR--SHSKAKHSLPSAYRTVRRS---------------- 802
Query: 251 GHGMKNHSRS-RSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRR 309
++ SRS R +HSP R ++S A R SRS G + R H K RR
Sbjct: 803 ----RSRSRSPRRRAHSPERRREERSVPTA---YRVSRSPGASRKRTRSRSPHEKKKKRR 855
Query: 310 ETGQTRSP------SPKKEVYQRRHAP----GYTRKLSAEELERKRQEMMENAKWREEER 359
+T+S SP K+ R AP ++ +S E QE +E +
Sbjct: 856 SRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915
Query: 360 LN 361
++
Sbjct: 916 IS 917
Score = 57.0 bits (136), Expect = 3e-08
Identities = 76/319 (23%), Positives = 133/319 (41%), Gaps = 52/319 (16%)
Query: 147 EEKKREVLNNPVKMKKIKE-------------LLQMSLEKKEKKKKKEKKKKHKKHKH-- 191
EEKK ++ ++ K+ K+ L Q S E KEK+ + E+K+K
Sbjct: 635 EEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTL 694
Query: 192 RSSSSDRSSSEDEHSAGRSQKKMANSSPVLS-KVPGYGLQVRNSDR-NQGLQGPLTAEQK 249
++ + + + E S ++ P+L+ P L+V+ DR + + P E+K
Sbjct: 695 KNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEK 754
Query: 250 RGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRS-----RSLGR-RSRSPRPSKLHN 303
K+ RSR+ S SP H+S KS + S+ + S R++ R RSRS P + +
Sbjct: 755 EKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAH 814
Query: 304 SKVNRRETGQTRSPSPKKEVYQRRHAPGYTRK----LSAEELERKRQEMMENAKWREEER 359
S RRE + Y+ +PG +RK S E ++KR+ +
Sbjct: 815 SPERRREERSVPT------AYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQS 868
Query: 360 LNILKRHAKD-----------------EEREQRLEKLDSRDGKFIHRMKLESASTSSLED 402
++ K+ A E R E+ SR ++ SA SS++
Sbjct: 869 VSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQER--SRGVSQEKEAQISSAIVSSVQS 926
Query: 403 RVKRNIYSLQRTSVALEKN 421
++ +++ + R +A KN
Sbjct: 927 KITQDLMAKVRAMLAASKN 945
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 58.5 bits (140), Expect = 1e-08
Identities = 70/384 (18%), Positives = 164/384 (42%), Gaps = 45/384 (11%)
Query: 12 WHPQTLRNVEKVWKAEQKHEAERKKIEELQRELR--EERAREEMQRYAEDVGAVKKKEEK 69
W+ + EK+W+ E+K + +KI+E + ++R EE+ RE+ ++ + +KEEK
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 70 LDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLD 129
M + M ++E + R +++ ++EK EEK + +
Sbjct: 351 ---MRRQEEMMWEKEEKM--RRLEEMMWEK-EEKIRELEEK-----------------MH 387
Query: 130 MASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKK--KKHK 187
KIRE +++EEEK RE + K+ + E++EK +++EKK ++ +
Sbjct: 388 EQEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 188 KHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAE 247
K + + +++ R ++K+ + + ++ ++ + + + +
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE----KMHEQEKIRKQEEKVWRQ 500
Query: 248 QKRGHGMKNHSRSRSSS---HSPPRHASKKSTREAGSRDRRSRSLGRRSR---SPRPSKL 301
+++ H + R + ++ RE + R + + + K+
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 302 HNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMM---ENAKWREEE 358
+ RR+ + R K + + + EE R+++EMM E W +EE
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 359 RLNILKRHAKDEEREQRLEKLDSR 382
++ ++ K +E+E+++ + + +
Sbjct: 621 KM--CEQEEKMQEQEEKMRRQEEK 642
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 26/203 (12%)
Query: 9 KKSWHPQTL--RNVEKVWKAEQKHEAERKKIEELQREL--REERAREEMQRYAEDVGAVK 64
K+ H Q + EKVW+ E+K + +KI E + ++ +EE+ RE+ ++ E ++
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 65 KKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGA 124
++EE M+ E +G EKM+E+E E +
Sbjct: 541 EQEE-----------MMQEQEEKMGEQE-----EKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 125 NSLLDMASKIREDPLFIIRKKE--EEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEK 182
+ + KI E I ++E +E++ ++ KM + +E +Q E++EK +++E+
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ---EQEEKMRRQEE 641
Query: 183 KKKHKKHKHRSSSSDRSSSEDEH 205
K ++ + R ++ EH
Sbjct: 642 KMWEQEVRLR-QQEEKMQEHQEH 663
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/242 (20%), Positives = 95/242 (39%), Gaps = 15/242 (6%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
+KEE+ +R+ K +K++ L +M EK+EK ++ E+K H++ K R R E
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM-HEQEKIREQEEKRQEEEK 404
Query: 204 EHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
+ Q++ A K+ ++R ++ Q EQ++ R
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK----IREEEKRQE 460
Query: 264 SHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEV 323
R K +E R + + R KV R+E ++E
Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK------QEEKVWRQE----EKMHDQEEK 510
Query: 324 YQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRD 383
+ + + ++ E E K +E E + +EE ++ + EE+ Q EK+ ++
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 384 GK 385
K
Sbjct: 571 EK 572
Score = 38.9 bits (89), Expect = 0.009
Identities = 47/225 (20%), Positives = 102/225 (45%), Gaps = 43/225 (19%)
Query: 9 KKSWHPQTLRNVEKV------WKAEQK-HEAE--RKKIEELQREL-----REERAREEMQ 54
K+ + R EK+ W+ ++K HE E RK+ E++ R+ +EE+ RE+ +
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 55 RYAEDVGAVKKKEEKL---DWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSET 111
+ ++++EEK+ + + M+ E +G EKM+E+E E
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ-----EEKMQEQEKMRRQE- 570
Query: 112 GLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSL 171
+ + KIRE ++K E++ ++ K+++ +E++Q
Sbjct: 571 -------------EKIREQEEKIREQ-----KEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 172 EK--KEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKM 214
EK ++++K E+++K ++ + + + E E + ++KM
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
Score = 36.6 bits (83), Expect = 0.044
Identities = 64/372 (17%), Positives = 147/372 (39%), Gaps = 72/372 (19%)
Query: 26 AEQKHEAERKKIEELQRE------------LREERAREEMQRYAEDVGAVKKKEEKLDWM 73
A QK +A+R IEEL +E + +E +E+ + E + V+ ++ ++
Sbjct: 185 ATQKKKADRY-IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN 243
Query: 74 YQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASK 133
+ + R + LL + ++++ + E + + A N L + ++
Sbjct: 244 VKELKRKLERAKLLLPQ-------QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 296
Query: 134 IREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRS 193
+E+ ++ +K +E + ++ K+++ +E ++ E++EK +++E+ K+ K R
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR---EQEEKMRRQEEMMWEKEEKMRR 353
Query: 194 SSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHG 253
+ E E R ++ M E+ R
Sbjct: 354 Q--EEMMWEKEEKMRRLEEMMWEKE----------------------------EKIRELE 383
Query: 254 MKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQ 313
K H + + R +K RE R + + R+ R + K+ +E
Sbjct: 384 EKMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQE---EKIREQE--- 436
Query: 314 TRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEERE 373
K+++++ K+ EE ++++EM WR+EE++ + + +E+
Sbjct: 437 -------KKMWRQEEKIHEQEKIREEEKRQEQEEM-----WRQEEKIREQEEIWRQKEKM 484
Query: 374 QRLEKLDSRDGK 385
EK+ ++ K
Sbjct: 485 HEQEKIRKQEEK 496
Score = 31.2 bits (69), Expect = 1.9
Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 4 GDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQREL--REERAREEMQRYAEDVG 61
G+ K + R EK+ + E+K +++KI E + ++ +EE+ RE+ + E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Query: 62 AVKKKEEKL 70
+ ++EEK+
Sbjct: 614 KMWEQEEKM 622
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.5 bits (140), Expect = 1e-08
Identities = 79/393 (20%), Positives = 159/393 (40%), Gaps = 33/393 (8%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREER-AREEMQRYAEDVGAVKKKEEKLDWMYQGPGG 79
EK+W+ E++ + K++ E ++ELRE++ RE+ ++ E + ++EEK M +
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEK---MREQEEK 370
Query: 80 MVNRDEYLLGRPIDKYVFE---KMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIRE 136
M ++E L + +K + E KM ++E + L + + K+RE
Sbjct: 371 MWRQEERLWEQ--EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE 428
Query: 137 DPLFIIRKK----EEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHK-- 190
+ ++K +EEK +E + KK++E + E++EK +K+E+ ++ K
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Query: 191 --HRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQ 248
R E E + +K + + +G ++ Q + ++
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG-----QEKKMWRQEKMREQE 543
Query: 249 KRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSR--DRRSRSLGRRSRSPRPSKLHNSKV 306
+ + R + +K T+E + D+ + R K+ +
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 307 NRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEE------RL 360
RE Q ++E Q + + ++ +E E K E E W +EE RL
Sbjct: 604 MMRE--QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE-QEEKMWEQEEKMWEQQRL 660
Query: 361 NILKRHAKDEEREQRLEKLDSRDGKFIHRMKLE 393
K + E+ Q EK+ ++ K + K+E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Score = 50.4 bits (119), Expect = 3e-06
Identities = 69/389 (17%), Positives = 163/389 (41%), Gaps = 32/389 (8%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRELR--------EERAREEMQRYAEDVGAVKKK 66
+ +R EK+W+ +K E KK++E +++ R EER RE ++ E+ ++++
Sbjct: 411 ERMREQEKMWEQVEKMR-EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 67 EEKLDWMYQGPGGMVNRDEYLLGRPIDK---YVFEKMEEKEAGCSSETGLLPGSIFAPSG 123
EEK+ + ++ P K + EKM+E+E + + G
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ-EEMWG 528
Query: 124 ANSLLDMASKIR--EDPLFIIRKKEEEKKREVLNNPVKM-KKIKELLQMSLEKKEK---- 176
+ K+R ED ++ +K ++++++ + +M KK +E + + +++EK
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE 588
Query: 177 KKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDR 236
++ +E++KK ++ + + E E ++KM K+ ++ +
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE---EKMQEQEEKMWEQEE 645
Query: 237 NQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSP 296
Q EQ+R + + H + K +E + + ++++
Sbjct: 646 KMWEQEEKMWEQQR----LPEQKEKLWEHEKMQEQEKMQEQE--EKIWEQEKMEKKTQEQ 699
Query: 297 RPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAK--W 354
K+ E+ + R ++E R ++ E+++ + +EM E + W
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE-QEEKMQEQEEEMWEQEEKMW 758
Query: 355 REEERLNILKRHAKDEEREQRLEKLDSRD 383
+EE++ +R + +E+ EK+ ++
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787
Score = 45.1 bits (105), Expect = 1e-04
Identities = 79/433 (18%), Positives = 174/433 (40%), Gaps = 55/433 (12%)
Query: 14 PQTLRNV--EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLD 71
PQ N E++W+ E++ + KKI + +EE+ + +R E G ++++EEK+
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRK-----QEEKMWRQEERLREQEGKMREQEEKM- 316
Query: 72 WMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMA 131
W R E L R +K ++ E+E + L + +
Sbjct: 317 W----------RQEKRL-REQEK----ELREQEKELREQKELREQEEQMQEQEEKMWEQE 361
Query: 132 SKIREDPLFIIRKKEE--EKKREVLNNPVKMKKIKELL----QMSLEKKEKKKKKEK--- 182
K+RE + R++E E+++++ KM+ +E + + EK+E+ +++EK
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 183 -------KKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSD 235
+KK ++ + ++ + E+E R +KKM + + +++ +
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER-EKKMREEEETMREQEE---KMQKQE 477
Query: 236 RNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRS 295
N Q +Q+R + K +E RD + G+ +
Sbjct: 478 ENMWEQEEKEWQQQR---LPEQKEKLWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKM 533
Query: 296 PRPSKLHNSKVNRRETGQTRSPSPKK-----EVYQRRHAPGYTRKLSAEELERKRQEMME 350
R K+ + E + +K E +++ + EE R+ + M E
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE 593
Query: 351 NAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRV---KRN 407
K EE + ++ K +E+E+++++ + + + +M+ + E+++ +
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK 653
Query: 408 IYSLQRTSVALEK 420
++ QR EK
Sbjct: 654 MWEQQRLPEQKEK 666
Score = 43.9 bits (102), Expect = 3e-04
Identities = 77/383 (20%), Positives = 151/383 (39%), Gaps = 56/383 (14%)
Query: 9 KKSWHPQTLRNVEKVWKAEQK--HEAERKKIEELQRELREERAREEMQRYAEDVGAVKKK 66
+K W Q R +K + E+K + E+ + EE RE RE++ REE + E ++++
Sbjct: 558 QKMWD-QEERMEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQ 615
Query: 67 EEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANS 126
EEK M ++E + + EKM+E+E +
Sbjct: 616 EEK----------MQEQEEKMWEQE------EKMQEQEEKMWEQ-------------EEK 646
Query: 127 LLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKH 186
+ + K+ E + +KE+ + E + KM++ +E + EK EKK ++++KK
Sbjct: 647 MWEQEEKMWEQQR-LPEQKEKLWEHEKMQEQEKMQEQEEKI-WEQEKMEKKTQEQEKKTW 704
Query: 187 KKHKHRSSSS----DRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQG 242
+ K R S ++ E+E ++KM K+ ++ + Q
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQE---EKMQEQEEEMWEQEEKMWEQE 761
Query: 243 PLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLH 302
EQ+R + + H + K +E RD+ + G+ K+
Sbjct: 762 EKMWEQQR----LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE------EKMR 811
Query: 303 NSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNI 362
+ R + +K Q G K+ +E + + + + K RE+E
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE--- 868
Query: 363 LKRHAKDEEREQRLEKLDSRDGK 385
K ++E+ ++ EK+ ++ K
Sbjct: 869 -KMRGQEEKMREQEEKMRGQEEK 890
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/215 (20%), Positives = 92/215 (42%), Gaps = 22/215 (10%)
Query: 9 KKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKK-- 66
KK+W + +R E + + E+K E + + E + +++E+ E+MQ E++ ++K
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ--EEKMQEQEEEMWEQEEKMW 758
Query: 67 --EEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGA 124
EEK+ W Q + + E L + EKM+E+E E +
Sbjct: 759 EQEEKM-WEQQ---RLPEQKEKL-------WEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 125 NSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKK 184
+ K+R +K ++ ++ KM +E + EK E+K + +++K
Sbjct: 808 EKMRGQEEKMRGQ-----EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862
Query: 185 KHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSP 219
++ + ++ ++E G+ +K SP
Sbjct: 863 MREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGSP 897
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 58.5 bits (140), Expect = 1e-08
Identities = 61/233 (26%), Positives = 96/233 (41%), Gaps = 31/233 (13%)
Query: 140 FIIRKKEEEKKREVLNNPV---------KMKKIKELLQMSLEKKEKKKKKEKKKKHKKHK 190
F+ KKEE K+R++ + K K+ KE + S EK+E+ + ++K
Sbjct: 123 FLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP 182
Query: 191 HRSSSSDRSSSEDEHS-AGRSQKKMANSSPVLSK------VPGYGLQVRNSDRNQGLQGP 243
R SS R + HS + R + K + SP K +P ++V+ +
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA---- 238
Query: 244 LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR---RSRSP---R 297
T+ K SP +++ K+ +E RSRS R RSRSP R
Sbjct: 239 -TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR 297
Query: 298 PSKLHNSKVN----RRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQ 346
P + H S+ RR R PSP++ RR P + S + R+R+
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRR 350
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/271 (24%), Positives = 109/271 (40%), Gaps = 30/271 (11%)
Query: 157 PVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDE-----HSAGRSQ 211
P + + KE KKEK+K+K + + + K RS + RS S S RS
Sbjct: 250 PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY 309
Query: 212 KKMANSSPVLSKVPGYGLQVRNSD---RNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPP 268
SP P R R++ + P+ ++ + S S SS S
Sbjct: 310 SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS--SRS 367
Query: 269 RHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTR-SPSPKKEVYQRR 327
R KK + S R++R L + PR + H +TR SP+P++ R+
Sbjct: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPR--RRHRPSPPATPPPKTRHSPTPQQSNRTRK 425
Query: 328 H----APGYTR-KLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSR 382
+PG T K++ + KR+ K R+ E +E++ ++ DS
Sbjct: 426 SRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE------LSESEEDKGGKMAAADSV 479
Query: 383 DGKFIHRMK-----LESASTSSLED-RVKRN 407
+ +R + +S S+SS ED R KR+
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
Score = 39.3 bits (90), Expect = 0.007
Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 247 EQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKV 306
EQ++ MK + K+S+RE R R R R+SRSP P + S
Sbjct: 137 EQEKLASMKKQDEDKDKRDKE----EKESSREKRERSRSPRR--RKSRSPSPRR--RSSP 188
Query: 307 NRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRH 366
RRE ++ S SP+ R +P +K EL ++ E + +ILK
Sbjct: 189 VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVP 248
Query: 367 AKD---EEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVK 405
+ E +E EK +S+ K + + S S S R +
Sbjct: 249 KPEPIPEPKEPSPEK-NSKKEKEKEKTRPRSRSRSKSRSRTR 289
Score = 38.1 bits (87), Expect = 0.015
Identities = 40/166 (24%), Positives = 66/166 (39%), Gaps = 6/166 (3%)
Query: 183 KKKHKKHKHRSS-SSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQ 241
++ ++ K R S S R+S + G +++ + +P KV L D+ +
Sbjct: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE---LSESEEDKGGKMA 474
Query: 242 GPLTAEQKRGHGMKNHSRSRSS--SHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPS 299
+ +Q+R + +N S S S S K+S + G RR R RS SP P
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 300 KLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKR 345
K R ++ SP P + AP R+ + R+R
Sbjct: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580
Score = 33.9 bits (76), Expect = 0.29
Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
Query: 172 EKKEKKKKKEKK-KKHKKH-KHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVP 225
+KK+KK KK+KK KKHKKH K ++ ++ +++ + + +A PV + P
Sbjct: 813 KKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
Score = 33.5 bits (75), Expect = 0.38
Identities = 45/215 (20%), Positives = 76/215 (35%), Gaps = 32/215 (14%)
Query: 145 KEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHK--------HRSSSS 196
++E KR + N ++ + S +K++KE + ++ + R S S
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Query: 197 DRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKN 256
+ ++ S P + P R S Q P ++R
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPS---PRRYSPPIQRRYSPSPPPKRRTASPPP 619
Query: 257 HSRSRSSSHSPPR----HASKKSTREAGSRDRRSRSLG-------------RRSRSPRPS 299
+ R+S PP+ H+ R + RRS SL R +RSP+P+
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN 679
Query: 300 KLHNSKVNRRETGQTRSPSPKK----EVYQRRHAP 330
K H+ R + SP P + QRR +P
Sbjct: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP 714
Score = 32.7 bits (73), Expect = 0.64
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 14/141 (9%)
Query: 190 KHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSK-VPGYGLQVRN-SDRNQGLQGPLTAE 247
K R+S S HS Q+ SSPV + P + R S ++ + + +
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQR----SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
Query: 248 QKRGHGMKNHSRSRSSSHSPP--RHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNS- 304
+ H R+ +S SPP R + S + S +R + R SR+P P K+ +
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Query: 305 -----KVNRRETGQTRSPSPK 320
V R + ++ S SP+
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPE 758
Score = 32.0 bits (71), Expect = 1.1
Identities = 13/19 (68%), Positives = 16/19 (84%)
Query: 172 EKKEKKKKKEKKKKHKKHK 190
+KK+K KK +K KKHKKHK
Sbjct: 811 KKKKKDKKHKKDKKHKKHK 829
Score = 31.2 bits (69), Expect = 1.9
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Query: 173 KKEKKKKKEKKKKHKKH-KHRSSSSDRS 199
KK+KKKK +K KK KKH KH+ +++
Sbjct: 809 KKKKKKKDKKHKKDKKHKKHKKHKKEKA 836
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/237 (21%), Positives = 94/237 (39%), Gaps = 34/237 (14%)
Query: 172 EKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQV 231
E K+K KK K ++H +H S + E+ R ++K SS
Sbjct: 15 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS------------- 61
Query: 232 RNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR 291
+G + ++R H ++ R +S S S R S+ +RE RSR R
Sbjct: 62 ------RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115
Query: 292 RSRS-PRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRH----------APGYTRKLSAEE 340
R RS R H + R ++RS KK + + R P + + +A +
Sbjct: 116 RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 175
Query: 341 LERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESAST 397
+ +E AK +E+R ++ +++++Q + + G ++ L ++ T
Sbjct: 176 AQEALARRLERAKKLQEQR----EKEMVEKQKQQEIAAAAATGGSVLNVAALLASGT 228
Score = 42.7 bits (99), Expect = 6e-04
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 19/155 (12%)
Query: 253 GMKNHSRSRSSS-HSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRET 311
G ++ S+ +SS H H K+ + + G R+R + S R H K +
Sbjct: 11 GRRHESKDKSSKKHKSEEHNDKEHSSDKG-RERLNSSENGEDR-------HKRKERKSSR 62
Query: 312 GQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEE 371
G++ S S +E RRH + + R+R++ ++ R++ R ++ E
Sbjct: 63 GRSHSRSRSRE---RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR-------SRSRE 112
Query: 372 REQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
R++R+ + HR + S + S DR KR
Sbjct: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 147
Score = 37.0 bits (84), Expect = 0.034
Identities = 29/159 (18%), Positives = 64/159 (40%), Gaps = 14/159 (8%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
++KE + R ++ + ++ + + KK + + +E+KK + + R S RS
Sbjct: 54 KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
RS+ + + S+ + R+ DR + ++ P + SRS S
Sbjct: 114 KRRIRSRSRSRSRHRHRTRSR---SRTRSRSRDRKKRIEKP-----------RRFSRSLS 159
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKL 301
+ SPP + + +A R ++ + R ++
Sbjct: 160 RTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEM 198
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 33/232 (14%)
Query: 160 MKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSS--DRSSSEDEHSAGRSQKKMANS 217
MK+++E + E KK+EK ++H S S R+ S H RS+ + +
Sbjct: 223 MKRVREAQSLISAAIEPDKKEEK----RRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSH 278
Query: 218 SPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTR 277
S S+ + R S + +G + + K + + S +PP+ S
Sbjct: 279 SKSRSRRRSKSPRRRRSHSRE--RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRS 336
Query: 278 EAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLS 337
+ SR+RR R +RSP+ + K+ +RSPSP RRH
Sbjct: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKL-------SRSPSP------RRH--------- 374
Query: 338 AEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHR 389
+ E+K+ + E ++ E ER K+ +KD+E+++ + +D K + R
Sbjct: 375 --KKEKKKDKDKERSR-DERERSTSKKKKSKDKEKDRERKSESDKDVKQVTR 423
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/274 (19%), Positives = 115/274 (41%), Gaps = 37/274 (13%)
Query: 145 KEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDE 204
K + +E+ ++++ + L+ ++E KKE+K++H + + RS R+ S
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPD----KKEEKRRHSRSRSRSRRR-RTPSSSR 265
Query: 205 HSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSS 264
H RS+ + + S S+ + R S + +G + + K + + S
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE--RGRRSRSTSKTRDKKKEDKEKKRS 323
Query: 265 HSPPRHASKKSTREAGSRDRRSRSLGRRSRSPR------------PSKLHNSKVNRRETG 312
+PP+ S + SR+RR R +RSP+ PS + K +++
Sbjct: 324 KTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKD 383
Query: 313 QTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEER 372
+ RS ++ ++K +++ E+ R+ E+ K +K+ +D +
Sbjct: 384 KERSRDERER--------STSKKKKSKDKEKDRERKSESDK--------DVKQVTRDYDE 427
Query: 373 EQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
E+ + DS K + +E+ S + E V++
Sbjct: 428 EE--QGYDSEKEKKEEKKPIETGSPKTKECSVEK 459
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 57.4 bits (137), Expect = 2e-08
Identities = 71/271 (26%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 165 ELLQMSLEKKEKKKKKEKKKKHKKHKHRSS-----SSDRSS-------SEDEHSAGRSQK 212
+L+ + K + KK+ KK+ +K RSS +SDRSS E++ S+ +S+K
Sbjct: 435 QLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEK 494
Query: 213 KMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHAS 272
K + + K+ G ++ + G G + K+ K S S+S H +
Sbjct: 495 KESKDT---KKIEG-----KDEKNDNGASGQTSESIKKSEEKKRIS-SKSPGHMVILDQT 545
Query: 273 KKSTREAGSRDRRSRSLGRRSRSPRPS--KLHNSKVNRRETGQTRSPSPK-KEVYQRRHA 329
K R R + GR R S K + R+E P K KE R H
Sbjct: 546 KGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEI----LPFEKMKEQRLREHL 601
Query: 330 PGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHR 389
+ R A EL R+R+E+ E + RE ER+ I++ + E ++ E+L+ I R
Sbjct: 602 VRFERLRRAMEL-RRRREIAERER-RERERIRIIREREERERLQRERERLE------IER 653
Query: 390 MKLESASTSSLEDRVKRNIYSLQRTSVALEK 420
KLE +R++R +R + E+
Sbjct: 654 QKLE-------RERMERERLERERIRIEQER 677
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/273 (24%), Positives = 111/273 (40%), Gaps = 35/273 (12%)
Query: 173 KKEKKKKKEKKKKHKKHKHRSSSSDRSSS-------EDEHSAGRSQKKMANSSPVLSKVP 225
KKE KK+ ++K + + ++SDRSS E++ S+ +S+KK + + K+
Sbjct: 448 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDT---KKIE 504
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRR 285
G ++ + G G + K+ K S S+S H +K R R
Sbjct: 505 G-----KDEKNDNGASGQTSESIKKSEEKKRIS-SKSPGHMVILDQTKGDHCRPSRRGRY 558
Query: 286 SRSLGRRSRSPRPS--KLHNSKVNRRETGQTRSPSPK-KEVYQRRHAPGYTRKLSAEELE 342
+ GR R S K + R+E P K KE R H + R A EL
Sbjct: 559 EKIHGRSKEKERASLDKKRDKDYRRKEI----LPFEKMKEQRLREHLVRFERLRRAMELR 614
Query: 343 RKR---------QEMMENAKWREE-ERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKL 392
R+R +E + + REE ERL + + E ++ E+++ R+ R+++
Sbjct: 615 RRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERME-RERLERERIRI 673
Query: 393 ESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR 425
E E R+ R L+R L KR
Sbjct: 674 EQERRKEAE-RIAREREELRRQQQQLRYEQEKR 705
Score = 40.4 bits (93), Expect = 0.003
Identities = 79/370 (21%), Positives = 144/370 (38%), Gaps = 37/370 (10%)
Query: 25 KAEQKHEAERKKIEELQRELREERAREEMQRYA--EDVGAVKKKEEKLDWMYQGPGGMVN 82
K E+K +E+ + +E + + E E+ A + ++KK EEK + PG MV
Sbjct: 482 KKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVI 541
Query: 83 RDEYLLG--RPIDKYVFEKM----EEKEAGCSSE--------TGLLPGSIFAPSGANSLL 128
D+ RP + +EK+ +EKE + +LP L
Sbjct: 542 LDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL 601
Query: 129 DMASKIREDPLFIIRKK--EEEKKREVLNNPVKMKKIKELLQMSLEKKE---KKKKKEKK 183
++R R++ E E++ ++ ++ +E LQ E+ E +K ++E+
Sbjct: 602 VRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERM 661
Query: 184 KKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGP 243
++ + + R E E A R ++++ L Y + RNS L+ P
Sbjct: 662 ERERLERERIRIEQERRKEAERIA-REREELRRQQQQLR----YEQEKRNS-----LKRP 711
Query: 244 LTAEQKRGHGMKNHSRSRS-SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLH 302
+ +R + ++ S + + H S S ++ D R R R P S +
Sbjct: 712 RDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHR---ERGRFPESSAVQ 768
Query: 303 NSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNI 362
+S RR+ +S K RR P + R R+ + + RE +R +
Sbjct: 769 SSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREV 828
Query: 363 LKRHAKDEER 372
R +DE R
Sbjct: 829 --RGERDERR 836
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 57.4 bits (137), Expect = 2e-08
Identities = 71/271 (26%), Positives = 116/271 (42%), Gaps = 43/271 (15%)
Query: 165 ELLQMSLEKKEKKKKKEKKKKHKKHKHRSS-----SSDRSS-------SEDEHSAGRSQK 212
+L+ + K + KK+ KK+ +K RSS +SDRSS E++ S+ +S+K
Sbjct: 453 QLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEK 512
Query: 213 KMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHAS 272
K + + K+ G ++ + G G + K+ K S S+S H +
Sbjct: 513 KESKDT---KKIEG-----KDEKNDNGASGQTSESIKKSEEKKRIS-SKSPGHMVILDQT 563
Query: 273 KKSTREAGSRDRRSRSLGRRSRSPRPS--KLHNSKVNRRETGQTRSPSPK-KEVYQRRHA 329
K R R + GR R S K + R+E P K KE R H
Sbjct: 564 KGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEI----LPFEKMKEQRLREHL 619
Query: 330 PGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHR 389
+ R A EL R+R+E+ E + RE ER+ I++ + E ++ E+L+ I R
Sbjct: 620 VRFERLRRAMEL-RRRREIAERER-RERERIRIIREREERERLQRERERLE------IER 671
Query: 390 MKLESASTSSLEDRVKRNIYSLQRTSVALEK 420
KLE +R++R +R + E+
Sbjct: 672 QKLE-------RERMERERLERERIRIEQER 695
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/273 (24%), Positives = 111/273 (40%), Gaps = 35/273 (12%)
Query: 173 KKEKKKKKEKKKKHKKHKHRSSSSDRSSS-------EDEHSAGRSQKKMANSSPVLSKVP 225
KKE KK+ ++K + + ++SDRSS E++ S+ +S+KK + + K+
Sbjct: 466 KKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDT---KKIE 522
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRR 285
G ++ + G G + K+ K S S+S H +K R R
Sbjct: 523 G-----KDEKNDNGASGQTSESIKKSEEKKRIS-SKSPGHMVILDQTKGDHCRPSRRGRY 576
Query: 286 SRSLGRRSRSPRPS--KLHNSKVNRRETGQTRSPSPK-KEVYQRRHAPGYTRKLSAEELE 342
+ GR R S K + R+E P K KE R H + R A EL
Sbjct: 577 EKIHGRSKEKERASLDKKRDKDYRRKEI----LPFEKMKEQRLREHLVRFERLRRAMELR 632
Query: 343 RKR---------QEMMENAKWREE-ERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKL 392
R+R +E + + REE ERL + + E ++ E+++ R+ R+++
Sbjct: 633 RRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERME-RERLERERIRI 691
Query: 393 ESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR 425
E E R+ R L+R L KR
Sbjct: 692 EQERRKEAE-RIAREREELRRQQQQLRYEQEKR 723
Score = 40.4 bits (93), Expect = 0.003
Identities = 79/370 (21%), Positives = 144/370 (38%), Gaps = 37/370 (10%)
Query: 25 KAEQKHEAERKKIEELQRELREERAREEMQRYA--EDVGAVKKKEEKLDWMYQGPGGMVN 82
K E+K +E+ + +E + + E E+ A + ++KK EEK + PG MV
Sbjct: 500 KKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVI 559
Query: 83 RDEYLLG--RPIDKYVFEKM----EEKEAGCSSE--------TGLLPGSIFAPSGANSLL 128
D+ RP + +EK+ +EKE + +LP L
Sbjct: 560 LDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL 619
Query: 129 DMASKIREDPLFIIRKK--EEEKKREVLNNPVKMKKIKELLQMSLEKKE---KKKKKEKK 183
++R R++ E E++ ++ ++ +E LQ E+ E +K ++E+
Sbjct: 620 VRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERM 679
Query: 184 KKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGP 243
++ + + R E E A R ++++ L Y + RNS L+ P
Sbjct: 680 ERERLERERIRIEQERRKEAERIA-REREELRRQQQQLR----YEQEKRNS-----LKRP 729
Query: 244 LTAEQKRGHGMKNHSRSRS-SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLH 302
+ +R + ++ S + + H S S ++ D R R R P S +
Sbjct: 730 RDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDFDHR---ERGRFPESSAVQ 786
Query: 303 NSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNI 362
+S RR+ +S K RR P + R R+ + + RE +R +
Sbjct: 787 SSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSRRNEPPPPRNELRESDRREV 846
Query: 363 LKRHAKDEER 372
R +DE R
Sbjct: 847 --RGERDERR 854
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 57.4 bits (137), Expect = 2e-08
Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 34/326 (10%)
Query: 88 LGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEE 147
L RP+ E++ AG E LL + A S + + R K +
Sbjct: 1733 LVRPLLPKDMERLTSLRAGI--EGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDY 1790
Query: 148 EKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSA 207
E +V + K KK K + EKK + + K+ K +H+S R+S +
Sbjct: 1791 EIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK--RTSESRSRAR 1848
Query: 208 GRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS------R 261
RS K ++ S S+ + + R++ +++KR K+ S+S R
Sbjct: 1849 KRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKR 1908
Query: 262 SSS-------HSPPRHASKKSTREAGSRDRRSRSLG----------RRSRSPRPSKLHNS 304
SSS + R S++S SR RRSRS+G RRSR+P S
Sbjct: 1909 SSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPS 1968
Query: 305 KVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERK-------RQEMMENAKWREE 357
+ +R + ++R+PS + RR R+ S + R+ R R
Sbjct: 1969 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRF 2028
Query: 358 ERLNILKRHAKDEEREQRLEKLDSRD 383
R I ++ ++ ER + ++L D
Sbjct: 2029 SRSPIRRKRSRSSERGRSPKRLTDLD 2054
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/248 (22%), Positives = 97/248 (39%), Gaps = 29/248 (11%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
K E+EKKR+ + K+ K S ++ + + + +K+ K HRS + RS S
Sbjct: 1811 KGEKEKKRDSSLRS-RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 204 EHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
+ RS+ K V + + R+ R + + + + ++ ++ + SR S
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 264 -SHSP-------------------------PRHASKKSTREAGSRDRRSRSLGRRSRSPR 297
SH+P P S+ +R + + RRSR+ RRSR+P
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Query: 298 PSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREE 357
S+ R + R V RR R+ S + RKR E + R
Sbjct: 1990 RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSE--RGRSP 2047
Query: 358 ERLNILKR 365
+RL L +
Sbjct: 2048 KRLTDLDK 2055
Score = 41.6 bits (96), Expect = 0.001
Identities = 62/262 (23%), Positives = 101/262 (38%), Gaps = 59/262 (22%)
Query: 170 SLEKKEKKKKKEKKKKHKKHKHRSSSSDR----SSSEDEHSAGRSQKKMANSSPVLSKVP 225
S K ++ K+K+ + KHRS S +R SSS D R++ + S S P
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP-SRRSRSHTP 1934
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS------SHSPPRHASKKSTRE- 278
+ R+ R + + + R ++ + SR S S +P R + S R
Sbjct: 1935 SRRRRSRSVGRRRSFSIS-PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1993
Query: 279 AGSRDRRSRSLGRR------------SRSPRPSKLHNSKVNR-RETGQTRSPSPKK---- 321
SR RRSRS+ RR SR+P + S + R R R SPK+
Sbjct: 1994 TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL 2053
Query: 322 ------EVYQR-----------------RHAPGYT------RKLSAEELERKRQEMMENA 352
E+ + + AP T +K +E ++ + A
Sbjct: 2054 DKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIA 2113
Query: 353 KWREEERLNILKRHAKDEEREQ 374
+ +E++ + + K H DEE E+
Sbjct: 2114 QSKEDDDVIVNKPHVSDEEEEE 2135
Score = 36.6 bits (83), Expect = 0.044
Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 21/135 (15%)
Query: 95 YVFEKMEEKEAGCSS--ETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKRE 152
+V K E + SS G L G P N D A+ R P I +K EE
Sbjct: 12 FVVSKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSG 71
Query: 153 VLNNPVKMKK-IKE------------------LLQMSLEKKEKKKKKEKKKKHKKHKHRS 193
VL+ ++ K +KE + S + K+ K KK+KKKK K+ K++
Sbjct: 72 VLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKR 131
Query: 194 SSSDRSSSEDEHSAG 208
+ S H G
Sbjct: 132 QPEESESKTKSHDDG 146
Score = 35.4 bits (80), Expect = 0.099
Identities = 32/145 (22%), Positives = 56/145 (38%), Gaps = 17/145 (11%)
Query: 257 HSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRS 316
H +S+ + + KK SR +RS+S +S R+ T ++RS
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS--------------RKRTSESRS 1845
Query: 317 PSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK--DEEREQ 374
+ K+ + H TR S R+ ++ R KR K + RE+
Sbjct: 1846 RARKRSSKSKSHR-SQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 375 RLEKLDSRDGKFIHRMKLESASTSS 399
+ ++ SRD + R + + S S
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRS 1929
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 57.4 bits (137), Expect = 2e-08
Identities = 77/326 (23%), Positives = 128/326 (39%), Gaps = 34/326 (10%)
Query: 88 LGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEE 147
L RP+ E++ AG E LL + A S + + R K +
Sbjct: 1733 LVRPLLPKDMERLTSLRAGI--EGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDY 1790
Query: 148 EKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSA 207
E +V + K KK K + EKK + + K+ K +H+S R+S +
Sbjct: 1791 EIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK--RTSESRSRAR 1848
Query: 208 GRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS------R 261
RS K ++ S S+ + + R++ +++KR K+ S+S R
Sbjct: 1849 KRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKR 1908
Query: 262 SSS-------HSPPRHASKKSTREAGSRDRRSRSLG----------RRSRSPRPSKLHNS 304
SSS + R S++S SR RRSRS+G RRSR+P S
Sbjct: 1909 SSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPS 1968
Query: 305 KVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERK-------RQEMMENAKWREE 357
+ +R + ++R+PS + RR R+ S + R+ R R
Sbjct: 1969 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRF 2028
Query: 358 ERLNILKRHAKDEEREQRLEKLDSRD 383
R I ++ ++ ER + ++L D
Sbjct: 2029 SRSPIRRKRSRSSERGRSPKRLTDLD 2054
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/248 (22%), Positives = 97/248 (39%), Gaps = 29/248 (11%)
Query: 144 KKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSED 203
K E+EKKR+ + K+ K S ++ + + + +K+ K HRS + RS S
Sbjct: 1811 KGEKEKKRDSSLRS-RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 204 EHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
+ RS+ K V + + R+ R + + + + ++ ++ + SR S
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 264 -SHSP-------------------------PRHASKKSTREAGSRDRRSRSLGRRSRSPR 297
SH+P P S+ +R + + RRSR+ RRSR+P
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Query: 298 PSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREE 357
S+ R + R V RR R+ S + RKR E + R
Sbjct: 1990 RRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSE--RGRSP 2047
Query: 358 ERLNILKR 365
+RL L +
Sbjct: 2048 KRLTDLDK 2055
Score = 41.6 bits (96), Expect = 0.001
Identities = 62/262 (23%), Positives = 101/262 (38%), Gaps = 59/262 (22%)
Query: 170 SLEKKEKKKKKEKKKKHKKHKHRSSSSDR----SSSEDEHSAGRSQKKMANSSPVLSKVP 225
S K ++ K+K+ + KHRS S +R SSS D R++ + S S P
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP-SRRSRSHTP 1934
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS------SHSPPRHASKKSTRE- 278
+ R+ R + + + R ++ + SR S S +P R + S R
Sbjct: 1935 SRRRRSRSVGRRRSFSIS-PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1993
Query: 279 AGSRDRRSRSLGRR------------SRSPRPSKLHNSKVNR-RETGQTRSPSPKK---- 321
SR RRSRS+ RR SR+P + S + R R R SPK+
Sbjct: 1994 TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDL 2053
Query: 322 ------EVYQR-----------------RHAPGYT------RKLSAEELERKRQEMMENA 352
E+ + + AP T +K +E ++ + A
Sbjct: 2054 DKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIA 2113
Query: 353 KWREEERLNILKRHAKDEEREQ 374
+ +E++ + + K H DEE E+
Sbjct: 2114 QSKEDDDVIVNKPHVSDEEEEE 2135
Score = 36.6 bits (83), Expect = 0.044
Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 21/135 (15%)
Query: 95 YVFEKMEEKEAGCSS--ETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKRE 152
+V K E + SS G L G P N D A+ R P I +K EE
Sbjct: 12 FVVSKFREIQQELSSGRNEGQLNGETNTPIEGNQAGDAAASARSLPNEEIVQKIEEVLSG 71
Query: 153 VLNNPVKMKK-IKE------------------LLQMSLEKKEKKKKKEKKKKHKKHKHRS 193
VL+ ++ K +KE + S + K+ K KK+KKKK K+ K++
Sbjct: 72 VLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKR 131
Query: 194 SSSDRSSSEDEHSAG 208
+ S H G
Sbjct: 132 QPEESESKTKSHDDG 146
Score = 35.4 bits (80), Expect = 0.099
Identities = 32/145 (22%), Positives = 56/145 (38%), Gaps = 17/145 (11%)
Query: 257 HSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRS 316
H +S+ + + KK SR +RS+S +S R+ T ++RS
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS--------------RKRTSESRS 1845
Query: 317 PSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK--DEEREQ 374
+ K+ + H TR S R+ ++ R KR K + RE+
Sbjct: 1846 RARKRSSKSKSHR-SQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 375 RLEKLDSRDGKFIHRMKLESASTSS 399
+ ++ SRD + R + + S S
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRS 1929
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/237 (22%), Positives = 104/237 (43%), Gaps = 17/237 (7%)
Query: 171 LEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQ 230
LE K++ K+KEK+ + + S SS +S S+ S ++SS S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG-SSRTSSRSSS 551
Query: 231 VRNSDRNQGLQGP-LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSL 289
+ R+ + P + A + R + S+ ++S R + R+RR
Sbjct: 552 PKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS 611
Query: 290 GRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMM 349
R R S+ + + NR ++RS +K QR + G + K E E++R++
Sbjct: 612 PSRERRRSRSRSRDRRTNR--ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK-- 667
Query: 350 ENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
E ++ +++R K +++++ + +K + +D KF SS +DR+KR
Sbjct: 668 ERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKF-----------SSQDDRLKR 713
Score = 53.9 bits (128), Expect = 3e-07
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 12/233 (5%)
Query: 175 EKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMAN--SSPVLSKVPGYGLQVR 232
E KK+ ++K+K + + SSSS SSS S+ S ++ SS S+ +
Sbjct: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPK 553
Query: 233 NSDRNQGLQGP-LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR 291
R+ + P + A + R + S+ ++S R + R+RR
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 292 RSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPG--YTRKLSAEELERKRQEMM 349
R R S+ + + NR ++RS +K QR + G + K A+E ERK++
Sbjct: 614 RERRRSRSRSRDRRTNR--ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
Query: 350 ---ENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSS 399
++ K +++ER + + ++RE++ K S+D + + K ES T S
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL--KRKRESERTFS 722
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 10/172 (5%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEK----KKKKEKKKKHKKHKHRSSSSDR 198
R+K ++++ + N K K + + E+ +KKK+K+++ ++ K +
Sbjct: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
Query: 199 SSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHS 258
S K+ S S+ +++ D Q + T + K+ G + S
Sbjct: 699 EKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG--SDS 756
Query: 259 RSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRS-PRPSKLHNSKVNRR 309
RSSS SP KK+ + S RSRS+ + RS + S+ H SK R
Sbjct: 757 SGRSSSESPGSSKEKKAKKPKHS---RSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 42.4 bits (98), Expect = 8e-04
Identities = 49/256 (19%), Positives = 100/256 (39%), Gaps = 25/256 (9%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R + ++ ++ +N ++K I++ + + E+++++ + ++ + RS S DR ++
Sbjct: 572 RSRSYSRRIKIESNRARVK-IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
S R ++K+ + LS NS +++G K R +
Sbjct: 631 ASRSRSRDRRKIDDQRGNLSG---------NSHKHKG-------------EAKEQERKKE 668
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
S S + KK +D+R R + + S + +RE+ +T S S
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
Query: 323 VYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK--DEEREQRLEKLD 380
V RH K S + +K + + E + ++ AK R + +EK
Sbjct: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ 788
Query: 381 SRDGKFIHRMKLESAS 396
K + K +S S
Sbjct: 789 RSGKKASRKHKSKSRS 804
Score = 40.0 bits (92), Expect = 0.004
Identities = 83/428 (19%), Positives = 148/428 (34%), Gaps = 77/428 (17%)
Query: 34 RKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGG--MVNRDEYLLGRP 91
R+ +E+++RE +++ +E M++ + KKE+K +G G + R ++
Sbjct: 237 REGLEKMEREKQKKLEKERMEQQRSQ---LSKKEKKATEDAEGGDGPRLPQRSKF----- 288
Query: 92 IDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKK------ 145
E E EA S + P + P +S +M + +E + ++ K
Sbjct: 289 DSDEEEEDTENVEAASSGKVTRSPSPV--PQEEHSDPEMTEEEKEYQMMLLTKMLLTEIL 346
Query: 146 -----------EEEKKREVLNNPVKMKKIKELL-------------------QMSLEKKE 175
++ R+ P K L + S E
Sbjct: 347 LDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSE 406
Query: 176 KKKKKEKKKKH----------KKHKHRSSSSDRSSSEDEHSAGRSQKKM-------ANSS 218
+++ +H +K K + D+ E++ R K+M NS
Sbjct: 407 SSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSL 466
Query: 219 PVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTRE 278
+L G V R + +K + RSRS S S +S T
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 279 AGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSA 338
S S S S S R S +S ++ ++RSP+ K +R + Y+R++
Sbjct: 527 TSS-TVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA---RRSRSRSYSRRIKI 582
Query: 339 EELERK---RQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESA 395
E + R N E ER R + RE+R + SRD + + S
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERER-----RRNRSPSRERRRSRSRSRDRRTNRASRSRSR 637
Query: 396 STSSLEDR 403
++D+
Sbjct: 638 DRRKIDDQ 645
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/237 (22%), Positives = 104/237 (43%), Gaps = 17/237 (7%)
Query: 171 LEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQ 230
LE K++ K+KEK+ + + S SS +S S+ S ++SS S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG-SSRTSSRSSS 551
Query: 231 VRNSDRNQGLQGP-LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSL 289
+ R+ + P + A + R + S+ ++S R + R+RR
Sbjct: 552 PKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRS 611
Query: 290 GRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMM 349
R R S+ + + NR ++RS +K QR + G + K E E++R++
Sbjct: 612 PSRERRRSRSRSRDRRTNR--ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKK-- 667
Query: 350 ENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKR 406
E ++ +++R K +++++ + +K + +D KF SS +DR+KR
Sbjct: 668 ERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKF-----------SSQDDRLKR 713
Score = 53.9 bits (128), Expect = 3e-07
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 12/233 (5%)
Query: 175 EKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMAN--SSPVLSKVPGYGLQVR 232
E KK+ ++K+K + + SSSS SSS S+ S ++ SS S+ +
Sbjct: 494 EPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPK 553
Query: 233 NSDRNQGLQGP-LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGR 291
R+ + P + A + R + S+ ++S R + R+RR
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 292 RSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPG--YTRKLSAEELERKRQEMM 349
R R S+ + + NR ++RS +K QR + G + K A+E ERK++
Sbjct: 614 RERRRSRSRSRDRRTNR--ASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSR 671
Query: 350 ---ENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSS 399
++ K +++ER + + ++RE++ K S+D + + K ES T S
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL--KRKRESERTFS 722
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 10/172 (5%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEK----KKKKEKKKKHKKHKHRSSSSDR 198
R+K ++++ + N K K + + E+ +KKK+K+++ ++ K +
Sbjct: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
Query: 199 SSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHS 258
S K+ S S+ +++ D Q + T + K+ G + S
Sbjct: 699 EKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSG--SDS 756
Query: 259 RSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRS-PRPSKLHNSKVNRR 309
RSSS SP KK+ + S RSRS+ + RS + S+ H SK R
Sbjct: 757 SGRSSSESPGSSKEKKAKKPKHS---RSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 42.4 bits (98), Expect = 8e-04
Identities = 49/256 (19%), Positives = 100/256 (39%), Gaps = 25/256 (9%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R + ++ ++ +N ++K I++ + + E+++++ + ++ + RS S DR ++
Sbjct: 572 RSRSYSRRIKIESNRARVK-IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
S R ++K+ + LS NS +++G K R +
Sbjct: 631 ASRSRSRDRRKIDDQRGNLSG---------NSHKHKG-------------EAKEQERKKE 668
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
S S + KK +D+R R + + S + +RE+ +T S S
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
Query: 323 VYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAK--DEEREQRLEKLD 380
V RH K S + +K + + E + ++ AK R + +EK
Sbjct: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQ 788
Query: 381 SRDGKFIHRMKLESAS 396
K + K +S S
Sbjct: 789 RSGKKASRKHKSKSRS 804
Score = 40.0 bits (92), Expect = 0.004
Identities = 83/428 (19%), Positives = 148/428 (34%), Gaps = 77/428 (17%)
Query: 34 RKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGG--MVNRDEYLLGRP 91
R+ +E+++RE +++ +E M++ + KKE+K +G G + R ++
Sbjct: 237 REGLEKMEREKQKKLEKERMEQQRSQ---LSKKEKKATEDAEGGDGPRLPQRSKF----- 288
Query: 92 IDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKK------ 145
E E EA S + P + P +S +M + +E + ++ K
Sbjct: 289 DSDEEEEDTENVEAASSGKVTRSPSPV--PQEEHSDPEMTEEEKEYQMMLLTKMLLTEIL 346
Query: 146 -----------EEEKKREVLNNPVKMKKIKELL-------------------QMSLEKKE 175
++ R+ P K L + S E
Sbjct: 347 LDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSE 406
Query: 176 KKKKKEKKKKH----------KKHKHRSSSSDRSSSEDEHSAGRSQKKM-------ANSS 218
+++ +H +K K + D+ E++ R K+M NS
Sbjct: 407 SSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSL 466
Query: 219 PVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTRE 278
+L G V R + +K + RSRS S S +S T
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 279 AGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSA 338
S S S S S R S +S ++ ++RSP+ K +R + Y+R++
Sbjct: 527 TSS-TVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA---RRSRSRSYSRRIKI 582
Query: 339 EELERK---RQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESA 395
E + R N E ER R + RE+R + SRD + + S
Sbjct: 583 ESNRARVKIRDRRRSNRNSIERER-----RRNRSPSRERRRSRSRSRDRRTNRASRSRSR 637
Query: 396 STSSLEDR 403
++D+
Sbjct: 638 DRRKIDDQ 645
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/212 (26%), Positives = 92/212 (43%), Gaps = 28/212 (13%)
Query: 184 KKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGP 243
++ + ++ RS+S RS S S S K+ G + R+ DR++ +
Sbjct: 3 RESRHYRKRSASRGRSGSRSR-SRSPSDKRSKR---------GDDRRSRSRDRDRRRERS 52
Query: 244 LTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRP----S 299
+ +++R RS S R ++ +R R RSRS GRRSRS P
Sbjct: 53 RSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSK 112
Query: 300 KLHNSKVNRRETGQTRSPSPK------KEVYQRRHAPGYTRKLSAEELERKRQEMMENAK 353
K N ++ +T S K KE + + A + + EE+ RKR+E +E K
Sbjct: 113 KTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEM-RKRKERVE--K 169
Query: 354 WREEERLNILKRHAKDEEREQRLEKLDSRDGK 385
WREE+R + A + E + E + + GK
Sbjct: 170 WREEQR-----KKAMENIGELKKEIEEMKQGK 196
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 56.2 bits (134), Expect = 5e-08
Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 8/131 (6%)
Query: 167 LQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSS-EDEHSAGRSQKKMANSSPVLSKVP 225
L S E+ KKK ++ + K S SS RSSS S RS+ + ++SS S+
Sbjct: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRR 285
R R++G + ++ RG SSS SP R+ + +R + S DR+
Sbjct: 245 S-----RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299
Query: 286 SRSLGRRSRSP 296
R RSRSP
Sbjct: 300 KRR--TRSRSP 308
Score = 42.4 bits (98), Expect = 8e-04
Identities = 47/192 (24%), Positives = 78/192 (40%), Gaps = 27/192 (14%)
Query: 176 KKKKKEKKKKH------KKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGL 229
+KKKK + K K+ + + S + +++ S + + LSK
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
Query: 230 QVRNSDRNQGLQGPLTAEQKRGHGMKNHSRS--RSSSHSPPRHASKKSTREAGSRDRRSR 287
+ +S++ + + + R +HSRS RSSS S R S+ +R + S RSR
Sbjct: 189 EEEDSNKKK------SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSR 242
Query: 288 SLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQE 347
S R R SK +S + R S SP+K Y+ S+ E RKR
Sbjct: 243 SSSRERSRSRGSKSRSSSRSHR-----GSSSPRKR--------SYSSSSSSPERNRKRSR 289
Query: 348 MMENAKWREEER 359
++ ++R
Sbjct: 290 SRSSSSGDRKKR 301
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 55.5 bits (132), Expect = 9e-08
Identities = 48/223 (21%), Positives = 81/223 (36%), Gaps = 14/223 (6%)
Query: 132 SKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKH 191
S+IRE I +KE +K+RE + ++ K + E+K ++ KKEKK + KK +
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 192 RSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRG 251
R E +KK R +G + E+KR
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKE-------------RGRTSKEGKERERKEERKRE 142
Query: 252 HGMKNHSRSRSSSHSPPRHASKKSTR-EAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRE 310
+ + R KK R + G ++ + R+ R R K R
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 311 TGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAK 353
+ +K+ +R+ R+ + E ER ++E E K
Sbjct: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 26/197 (13%)
Query: 18 RNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGP 77
R +E + +++ E+ERKK +R RE+R RE + + G KKE+K + +
Sbjct: 43 REIETRKEGKKERESERKK----ERREREKRKREREKERKRERG---KKEKKGERKKEER 95
Query: 78 GGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIRED 137
R E +K +K E+KE G +S+ G + RE+
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG------------KERERKEERKREE 143
Query: 138 PLFIIRKKEE-EKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSS 196
RKKEE EK+RE K +K +E Q+ EK+E++K+KE+K++ K+ ++R
Sbjct: 144 RKERERKKEEREKERE-----RKERKKRERKQVG-EKEEERKEKERKERKKRERNRKERK 197
Query: 197 DRSSSEDEHSAGRSQKK 213
++ + +KK
Sbjct: 198 KERERKERRERKKERKK 214
Score = 50.1 bits (118), Expect = 4e-06
Identities = 45/229 (19%), Positives = 91/229 (39%), Gaps = 19/229 (8%)
Query: 157 PVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMAN 216
P +I+E + +KE KK++E ++K K+ + R E + G+ +KK
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERK-KERREREKRKREREKERKRERGKKEKKGER 90
Query: 217 SSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKST 276
+ + R + +G E+++ + R R+S R ++
Sbjct: 91 KKEERERKK----RRREKENKEG------EEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 277 REAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKL 336
RE +R+ R + R + K R++ G+ +KE +R+ ++
Sbjct: 141 RE----ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 337 SAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGK 385
E ++R+E + K +EE + K KD + R ++ R+ K
Sbjct: 197 KKERERKERRERKKERKKKEERK----KERQKDRQTNWREKERGKRERK 241
Score = 31.6 bits (70), Expect = 1.4
Identities = 18/49 (36%), Positives = 30/49 (61%), Gaps = 3/49 (6%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEK 69
EK + ++K ERKK E ++E ++ER R+E + ++ KKKEE+
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKE---RKKKEER 218
Score = 30.4 bits (67), Expect = 3.2
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 8/115 (6%)
Query: 308 RRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKW--REEERLNILKR 365
R+E + R KKE +R ++ E ERKR+ + K ++EER +R
Sbjct: 48 RKEGKKERESERKKERRERE------KRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 366 HAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEK 420
K+ + + EK ++ K R E E+R + +R EK
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Score = 29.3 bits (64), Expect = 7.1
Identities = 15/52 (28%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDW 72
EK K +K E RK+ ++ +RE +E R R++ ++ E+ ++K+ + +W
Sbjct: 180 EKERKERKKRERNRKERKK-ERERKERRERKKERKKKEERKKERQKDRQTNW 230
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 55.5 bits (132), Expect = 9e-08
Identities = 52/265 (19%), Positives = 110/265 (41%), Gaps = 28/265 (10%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R+++ EK+RE + +E + + ++K++++EK ++ ++ + R + + +E
Sbjct: 151 RQRDAEKERERQTD-------RERQRQTERNRQKEREREKNRQERRERERQREKE-NKTE 202
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
D HS +++ + ++ + R +DR + Q E++ K R R+
Sbjct: 203 DRHSERGRERERERETETETE------RKRQTDRERDRQRKTERERE-----KQAERERA 251
Query: 263 SSHSPPRHASKKSTREAG-SRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKK 321
S R ++ R+ RDRR + R++ R + + R+ + R ++
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 322 EVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDS 381
E ++R E ER+R+ E + RE+ER KR + + R +
Sbjct: 312 ERNRKRERE--------RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 382 RDGKFIHRMKLESASTSSLEDRVKR 406
R R + S +R +R
Sbjct: 364 RRQAERERERERERDRQSAREREER 388
Score = 52.8 bits (125), Expect = 6e-07
Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 27/242 (11%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R+KE E++RE K + ++K +++++EK + K+ +HR DR E
Sbjct: 58 RQKERERRRE-----------KRQTERETDRK-RERRREKDRHRKRDRHRERQRDR-EKE 104
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
E R + + K + R ++R +G +G ++ G + R R
Sbjct: 105 RERQTDRERDRQREKERNRQKE-----RERETER-EGERG----RDRQTDGQRERERQRD 154
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
+ R ++ R+ ++ R + + R + K N+ E R +E
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE---DRHSERGRE 211
Query: 323 VYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHA-KDEEREQRLEKLDS 381
+ R T + + ER RQ E + ++ ER +R +D+ERE+ ++
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 382 RD 383
RD
Sbjct: 272 RD 273
Score = 50.4 bits (119), Expect = 3e-06
Identities = 62/348 (17%), Positives = 136/348 (39%), Gaps = 38/348 (10%)
Query: 18 RNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGP 77
R+ EK E++ + +R++ + +R ++ER RE+ ++ + ++KE K + +
Sbjct: 153 RDAEK----ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 78 GGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIRED 137
G R+ K ++ +++ E A + R
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTERERE----------------KQAERERAS 252
Query: 138 PLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSD 197
R KE E++R+ + + ++ KE + + K++++ +++++ + K+ + R +
Sbjct: 253 ERETERDKERERERD--RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERE 310
Query: 198 RSSS---EDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGM 254
R + E E R +++ + K +R + Q + E+ R G
Sbjct: 311 RERNRKRERERERERERERQRETERDREK---------ERERKRKRQTEMDRERNRQTGR 361
Query: 255 KNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQT 314
+ R R ++S RE R+ R R R + R + + +RET +
Sbjct: 362 EGR-RQAERERERERERDRQSARE---REERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 315 RSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNI 362
R +E + R K E +R+RQ + + R+ L +
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
Score = 49.7 bits (117), Expect = 5e-06
Identities = 47/257 (18%), Positives = 102/257 (39%), Gaps = 20/257 (7%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R+ + E++R+ N K ++ ++ Q E++ +++K+ K + + R +R +
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
+ ++ ++ + + R S+R + E++R R +
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERET--ERDKERERERDRDRDRDRRQKE 278
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
R +++ R+ + +R R R R K + RE + R +E
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
Query: 323 VYQRRHAPGYT--------------RKLSAEELERKRQEMMENAKWREEERLNILKRHAK 368
+ R T R+ + E ER+R+ ++A+ REE + + +
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD--RDRDR 396
Query: 369 DEEREQRLEKLDSRDGK 385
+ERE++ EK RDG+
Sbjct: 397 QKERERQTEK--DRDGQ 411
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/240 (19%), Positives = 91/240 (37%), Gaps = 17/240 (7%)
Query: 146 EEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKK-EKKKKHKKHKHRSSSSDRSSSEDE 204
E E+KR+ + +K + + E++ +++ E+ K+ ++ + R DR E E
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 205 HSAGRS-QKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSS 263
R Q++ K + R +RN+ + E++R R R +
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER-------ERQRET 333
Query: 264 SHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEV 323
+ +K R+ R+R GR R + + R++ + R +
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 324 YQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRD 383
R+ K + E+ R E K RE E+ +R ++ RE+ +K RD
Sbjct: 394 RDRQ-------KERERQTEKDRDGQRETEKQREREKDRESER-GRERGREREKQKGRERD 445
Score = 36.2 bits (82), Expect = 0.058
Identities = 66/323 (20%), Positives = 122/323 (37%), Gaps = 59/323 (18%)
Query: 15 QTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMY 74
+T R E+ + E++ E RK+ E +RE ER RE + ++ +K++ ++D
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD--- 352
Query: 75 QGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKI 134
NR GR + E+ E++ + E + +
Sbjct: 353 ----RERNRQTGREGRRQAERERERERERDRQSARER-----------------EERERD 391
Query: 135 REDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSS 194
R+ R+++ EK R+ K ++ + + +E ++ +E+ ++ +K K R
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQRERE-------KDRESERGRERGREREKQKGRER 444
Query: 195 SSDRSSSEDEHSAGRSQKK---MANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRG 251
+R + + AGR +K+ N P ++ V SD N+ +G
Sbjct: 445 DRER---QTDRQAGRQRKRSTLYVNPPPRTAR-----SGVVQSDPNRPTRG--------- 487
Query: 252 HGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPR-PSKLHNSKVNRRE 310
SS P+ AS + ++ R R GRR PR K RR
Sbjct: 488 -------IRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP 540
Query: 311 TGQTRSPSPKKEVYQRRHAPGYT 333
+G + +P + P YT
Sbjct: 541 SGGFGTENPLSQAPSVFPGPRYT 563
Score = 33.5 bits (75), Expect = 0.38
Identities = 26/128 (20%), Positives = 49/128 (38%), Gaps = 1/128 (0%)
Query: 259 RSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPS 318
R S SP R ++ ++A DR R R + +RE + +
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 319 PKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILK-RHAKDEEREQRLE 377
K++ ++ R + + ER RQ E + +E ER + +D + + + E
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 378 KLDSRDGK 385
+ RD +
Sbjct: 149 RERQRDAE 156
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 55.5 bits (132), Expect = 9e-08
Identities = 54/265 (20%), Positives = 104/265 (39%), Gaps = 19/265 (7%)
Query: 143 RKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSE 202
R+ E EK+R+ L K ++ + S+++ E+++ + +HRS S R
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRG-----LERRRSRSRERHRSRSRSRDRKG 347
Query: 203 DEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRS 262
D R ++K + R+ D+ +G + E+ R + SR
Sbjct: 348 DRRDRDREREKENERGR---------RRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398
Query: 263 SSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQ-TRSPSPKK 321
+H K R R S+ + SRS + H S+ R G+ +RS S +K
Sbjct: 399 EEK---KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455
Query: 322 EVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDS 381
+ + + K S + + + ++ K ++ ++ +ER + + DS
Sbjct: 456 SSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDS 515
Query: 382 RDGKFIH-RMKLESASTSSLEDRVK 405
+D H R + +S S E + K
Sbjct: 516 KDQSDKHDRRRSQSIEQESQEKQHK 540
Score = 39.7 bits (91), Expect = 0.005
Identities = 50/204 (24%), Positives = 77/204 (37%), Gaps = 14/204 (6%)
Query: 230 QVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSP---PRHASKKSTREAG----SR 282
Q++ R G AE+ H + SRS S SP PR + +S G S
Sbjct: 232 QIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSF 291
Query: 283 DRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRH-APGYTRKLSAEEL 341
DR R R R +K K RR R ++ + RH + +R +
Sbjct: 292 DRELEREKERQRLEREAK-EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRR 350
Query: 342 ERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLE 401
+R R+ EN + R +R + K+ E+ E+ SR+ R + E E
Sbjct: 351 DRDREREKENERGRRRDR-----DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405
Query: 402 DRVKRNIYSLQRTSVALEKNFMKR 425
D+ R +R S +K+ R
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSR 429
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 29/194 (14%)
Query: 21 EKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGM 80
E+ + ++ ++ ER E +RE ER++E QR +V K KE+K D +
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKE--QRSRGEVEEKKHKEDKDDRRH------ 412
Query: 81 VNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLF 140
RD+ + K+ + E++ S + + + +SK + +
Sbjct: 413 --RDDKRDSKKEKKHSRSRSRERKHRSRSRS-----RNAGKRSRSRSKEKSSKHKNE--- 462
Query: 141 IIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSS 200
KE+ KR + + +++ +K+E KEK +K + K RS D S
Sbjct: 463 ---SKEKSNKRSRSGSQGRTDSVEK-----SKKREHSPSKEKSRKRSRSKERSHKRDHSD 514
Query: 201 SEDE---HSAGRSQ 211
S+D+ H RSQ
Sbjct: 515 SKDQSDKHDRRRSQ 528
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 55.1 bits (131), Expect = 1e-07
Identities = 74/392 (18%), Positives = 159/392 (40%), Gaps = 48/392 (12%)
Query: 12 WHPQTLRNVEKVWKAEQKHEAERKKIEELQRELR--EERAREEMQRYAEDVGAVKKKEEK 69
W+ + EK+W+ E+K + +KI+E + ++R EE+ RE+ ++ + +KEEK
Sbjct: 352 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411
Query: 70 L----DWMYQGPGGMVNRDEYLLG-----RPIDKYVF--EKMEEKEAGCSSETGLLPGSI 118
+ + M++ M ++E + R +++ + EK+ E+E E +
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471
Query: 119 FAPSGA------NSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLE 172
A + + KIRE + R++E+ ++E + K ++ +E+ + +
Sbjct: 472 RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 531
Query: 173 KKE-------KKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVP 225
+E K+K E+++K +K + + + + E ++K+ K+
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE---EKIR 588
Query: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRR 285
++R + Q +T EQ+ G + ++ +E + RR
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE----------QEEKMQEQEEKMRR 638
Query: 286 SRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKR 345
R + K+ + RE + +K Q K+ +E + +R
Sbjct: 639 QEEKIRE----QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694
Query: 346 QEMMENAKWREEERLNILKRHAKDEEREQRLE 377
Q E W +E RL ++ K +E ++ LE
Sbjct: 695 Q---EEKMWEQEVRLR--QQEEKMQEHQEHLE 721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,495,527
Number of Sequences: 37866
Number of extensions: 923497
Number of successful extensions: 22246
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 459
Number of HSP's successfully gapped in prelim test: 840
Number of HSP's that attempted gapping in prelim test: 8572
Number of HSP's gapped (non-prelim): 6936
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.