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Search of human proteins with 8923110
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
(335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] 654 0.0
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] 654 0.0
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 339 2e-93
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan... 339 2e-93
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 62 6e-10
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 60 4e-09
gi|31982906 cingulin-like 1 [Homo sapiens] 59 5e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 59 6e-09
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 58 1e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 56 4e-08
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 56 4e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 5e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 55 9e-08
gi|32698688 citron [Homo sapiens] 55 9e-08
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 54 2e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 2e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 2e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 54 2e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 54 3e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 53 3e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 53 3e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 53 3e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 3e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 53 3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 53 3e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 53 4e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 53 4e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 53 4e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 53 4e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 53 4e-07
>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 654 bits (1687), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
Sbjct: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
Sbjct: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 654 bits (1687), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
Sbjct: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
Sbjct: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
>gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
Length = 345
Score = 339 bits (870), Expect = 2e-93
Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)
Query: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P
Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++
Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
>gi|71284108 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform A [Homo sapiens]
Length = 328
Score = 339 bits (870), Expect = 2e-93
Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)
Query: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P
Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++
Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 62.4 bits (150), Expect = 6e-10
Identities = 50/197 (25%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE---N 68
EEE + +QR EEL E E ++ ++A LE Q +ET N++L E
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+++ E E ++K + Q E + ++S E D + + + ++ K EL+ + LE A+
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVE-LAEKASKLQNELDNVSTLLEEAE 1300
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
+ I +D +Q + L+ E +K NL +++L++E L+++ Q+++E+
Sbjct: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ---QEEEEE 1357
Query: 189 PRTPMPSSVEAERTDTA 205
R + V A ++ A
Sbjct: 1358 ARKNLEKQVLALQSQLA 1374
Score = 50.4 bits (119), Expect = 2e-06
Identities = 54/231 (23%), Positives = 94/231 (40%), Gaps = 52/231 (22%)
Query: 19 KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68
K ++ Y + + + E RE + E + E + E E Q +Q+ DL+S
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520
Query: 69 NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117
+ + ELE K E Q E Q+ LED+L T+ K +L+ ++ R+L
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580
Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAF-------LESELDEKENLLESVQRLK 170
+ ++ E KR I + + E L ++ A +E +L + E +E+ + +
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640
Query: 171 DE---------------------ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
DE AR R E+ Q K+ + + S+EAE
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL---KSLEAE 1688
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/177 (24%), Positives = 85/177 (48%), Gaps = 24/177 (13%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88
AE + L ++ E +LE+++++ E RN+ L +E +++ ++ ++E ++ E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE--QLDEEE 963
Query: 89 GYRQISALEDDLAQTK---------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
G RQ LE A+ K ++DQ K+I+E + D R + E+ E
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMED---RIAECSSQLAEEEE 1020
Query: 140 QRLNQAIERN--AFLESELDE--------KENLLESVQRLKDEARDLRQELAVQQKQ 186
+ N A RN + S+L+E ++ L ++ ++L E DL+ ++A Q Q
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 13/193 (6%)
Query: 14 EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM 73
+ ++ + +A +++ + + L E + S Y E + + + LS L
Sbjct: 1435 DLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEE 1494
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
LE KE+FE RQ L D+ + KD + K + ELE++ LE+
Sbjct: 1495 ALEA-KEEFE-------RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546
Query: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPM 193
LE+ E L + LE + + E + +DE + ++ L ++Q +E +
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE-----L 1601
Query: 194 PSSVEAERTDTAV 206
+ +E ER A+
Sbjct: 1602 EAELEDERKQRAL 1614
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/194 (21%), Positives = 88/194 (45%), Gaps = 14/194 (7%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS-----------REYEAEL 50
+D GK E+ + + + E ++EL+ ++ ++E +L
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580
Query: 51 ETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI---K 107
+T+ +Q E + R L+ + L ELE +++ + + + L+D AQ +A +
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640
Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
D++ K +R+L+ D +R S ++ + ++ ++ LE+E+ + + L S +
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700
Query: 168 RLKDEARDLRQELA 181
R + A R ELA
Sbjct: 1701 RARRHAEQERDELA 1714
Score = 45.4 bits (106), Expect = 7e-05
Identities = 46/183 (25%), Positives = 82/183 (44%), Gaps = 21/183 (11%)
Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
E +++ +F + + E++L+ + ++ R L+ ++R+R +LE K + Q E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIR-QLEEEKNSLQEQQEEE 1355
Query: 90 Y-------RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
+Q+ AL+ LA TK D I LE+A L L+D E L
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL----------LKDAE-AL 1404
Query: 143 NQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERT 202
+Q +E A +L++ +N L+ Q L D DL + V EK + + E++
Sbjct: 1405 SQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462
Query: 203 DTA 205
+A
Sbjct: 1463 ISA 1465
Score = 42.0 bits (97), Expect = 8e-04
Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 32/141 (22%)
Query: 44 REYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQT 103
+E + ++E +L+++E +++ LL E N L +L+ E F A+
Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF------------------AEA 906
Query: 104 KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL 163
+ ++ +L +ELE+ L D E R+ + ERN L++E + + +
Sbjct: 907 EEMRARLAAKKQELEEI--------------LHDLESRVEEEEERNQILQNEKKKMQAHI 952
Query: 164 ESVQRLKDEARDLRQELAVQQ 184
+ ++ DE RQ+L +++
Sbjct: 953 QDLEEQLDEEEGARQKLQLEK 973
Score = 38.1 bits (87), Expect = 0.011
Identities = 36/195 (18%), Positives = 83/195 (42%), Gaps = 28/195 (14%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL---LSENNRLRMELETIKEKFE 83
+R + E + +E ++ +EA+++ Q+ T +L L + R + LE K+ E
Sbjct: 1171 KREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230
Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
+ E ++ L+ A+++ + +L ++EL + +R +
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV-------------- 1276
Query: 144 QAIERNAFLESELDEKENLLESVQR-----------LKDEARDLRQELAVQQKQEKPRTP 192
+ E+ + L++ELD LLE ++ L+ + +D ++ L + +Q+ +
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 193 MPSSVEAERTDTAVQ 207
+E E+ Q
Sbjct: 1337 RIRQLEEEKNSLQEQ 1351
Score = 38.1 bits (87), Expect = 0.011
Identities = 41/192 (21%), Positives = 89/192 (46%), Gaps = 19/192 (9%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
+E++ + KD A + + + ++TQE L QE +R+ + L ++++Q+E L +
Sbjct: 1299 AEKKGIKFAKDAA-SLESQLQDTQELL---QEETRQ-KLNLSSRIRQLEEEKNSLQEQQE 1353
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ---------- 119
+ ++++ S+ ++DDL +++++ +K +++ E
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLKDEARDL 176
A D LE+ K L+D L+ + + LE + + + LL +S+ E RD
Sbjct: 1414 AYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472
Query: 177 RQELAVQQKQEK 188
R E ++K+ K
Sbjct: 1473 RAEAEAREKETK 1484
Score = 36.6 bits (83), Expect = 0.032
Identities = 44/227 (19%), Positives = 97/227 (42%), Gaps = 49/227 (21%)
Query: 26 KQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
+ R E +E + Q ++ +A +LE QL + E + L E +++ ++E+
Sbjct: 928 ESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEI 987
Query: 83 ---EVQHSEGYRQISALEDDLAQTKA---------------------IKDQLQKYIRELE 118
E Q+S+ ++ +ED +A+ + + L++ +++ E
Sbjct: 988 LLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEE 1047
Query: 119 QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE------------------ 160
+ +LE+AKR D + ++ + + L+ +L +KE
Sbjct: 1048 KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKN 1107
Query: 161 NLLESVQRLKDEARDLRQ----ELAVQQKQEKPRTPMPSSVEAERTD 203
N L+ V+ L+ + +L++ E A + K EK + + +EA +T+
Sbjct: 1108 NALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
Score = 36.2 bits (82), Expect = 0.042
Identities = 41/204 (20%), Positives = 87/204 (42%), Gaps = 27/204 (13%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLL 65
+ EEE+A + + + +E L++ ++ +E E +L+ + ++ + +L
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 66 SENNRLRMELETIKEKFEVQHSEG-----------------YRQISALEDDLAQTKAIKD 108
++ + L+++L +E+ + + G QI+ L++D KA ++
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRN 1135
Query: 109 QLQKYIR----ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164
+ +K R ELE +LE T E +R + E LE +E +N
Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE---EETKNHEA 1192
Query: 165 SVQRLKDEARDLRQELAVQQKQEK 188
+Q ++ +EL+ Q +Q K
Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAK 1216
Score = 35.4 bits (80), Expect = 0.072
Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 23/218 (10%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
EE+A + L T K R + ++L + R+ + LE + ++ + LL+E +
Sbjct: 1409 EEKALAYDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD----QLLAEEKSI 1463
Query: 72 RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR-- 129
+++ E + E + +L L + K++ ++ ++L +DL +K
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 130 -ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQ----- 183
+ LE ++ L Q +E + ++L+E E+ L++ + K Q + Q
Sbjct: 1524 GKNVHELEKSKRALEQQVEE---MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580
Query: 184 -----QKQEKPRTPMPS--SVEAERTDTAVQATGSVPS 214
Q +EK R + +EAE D Q +V S
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618
Score = 34.3 bits (77), Expect = 0.16
Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 54/197 (27%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE-----------------NNR 70
R +EEL E Q Q++T N +L +E N
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 1796
Query: 71 LRMELE----TIKEKFEVQHSEGYRQISALEDDLAQT---------------KAIKD--- 108
L+ +L+ +K KF+ S +I LE+ L Q K +K+
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 109 -------QLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE--- 158
+Y ++E+AN +++ KR LE+ E+ +A L+ ELD+
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKR----QLEEAEEEATRANASRRKLQRELDDATE 1912
Query: 159 -KENLLESVQRLKDEAR 174
E L V LK+ R
Sbjct: 1913 ANEGLSREVSTLKNRLR 1929
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 59.7 bits (143), Expect = 4e-09
Identities = 59/228 (25%), Positives = 106/228 (46%), Gaps = 20/228 (8%)
Query: 1 MEDSGKTFSSEEEE---ANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI 57
ME S ++ +E+ ++L T Q AE + L E ++ +E ET+ + +
Sbjct: 1456 METSAQSSGDHQEQHVSVQEMQELKETLNQ-AETKSKSLESQVENLQKTLSEKETEARNL 1514
Query: 58 ETRNRDLLSENNRLRMEL-------ETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL 110
+ + L SE +RLR +L E ++++ + + + I A + +A +KDQL
Sbjct: 1515 QEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQL 1574
Query: 111 QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRL 169
K EL+Q N L++ K + + + + I R LE EL E +E LE
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISR---LERELREHQERHLEQ---- 1627
Query: 170 KDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPI 217
+DE ++ ++ QQ+Q +T P+S E T+ T ++ TP+
Sbjct: 1628 RDEPQEPSNKVPEQQRQITLKT-TPASGERGIASTSDPPTANIKPTPV 1674
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 24/205 (11%)
Query: 25 YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84
+ +R + EE+ + A L I++ DL N++R E ETI++ +
Sbjct: 1364 HTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL----NKVRTEKETIQKDLDA 1419
Query: 85 QHSEGYRQISALEDDL-------AQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLED 137
+ + ++ + Q + +K Q K + Q++ D + + ++ +++
Sbjct: 1420 KIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGD-HQEQHVSVQEMQE 1478
Query: 138 FEQRLNQAIERNAFLESE-------LDEKE----NLLESVQRLKDEARDLRQELAVQQKQ 186
++ LNQA ++ LES+ L EKE NL E +L+ E LRQ+L + Q
Sbjct: 1479 LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ 1538
Query: 187 EKPRTPMPSSVEAERTDTAVQATGS 211
E+ + E E+T A+ A S
Sbjct: 1539 EEQLRQQITEKE-EKTRKAIVAAKS 1562
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/227 (20%), Positives = 101/227 (44%), Gaps = 35/227 (15%)
Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNR--------DLLSENNRL 71
+L + K+ +N Q+E+ ++ E ++ +Q Q + + DL+S+ +
Sbjct: 885 NLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQT 944
Query: 72 RMELETIKEKFEVQHS--EGYR-QISALEDDLAQTKAIKD------------------QL 110
++ +KE+ + S E Y+ +++LE+ L + K + + QL
Sbjct: 945 EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQL 1004
Query: 111 QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170
+K + E+E+ +L+ KR I E EQ+L++ + + +++E+ E + +
Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAI---ESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 171 DEARDLRQE---LAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPS 214
+AR QE +AV+ + + R M + + E A + + S
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAS 1108
Score = 43.5 bits (101), Expect = 3e-04
Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 21/172 (12%)
Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
++ Y+QR E + EL+E Q+ S E E + ++ +L+ + + + +ET K
Sbjct: 1221 SLRYRQRVELLERELQELQD-SLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKML 1279
Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
E + LE DL Q +A +L+ I L++AN +L + E+
Sbjct: 1280 REEKER--------LEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Query: 142 LNQAIERNAFLESE------------LDEKENLLESVQRLKDEARDLRQELA 181
+ + RN L S+ L EKE + +Q+L +E L+ E+A
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIA 1383
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/219 (22%), Positives = 101/219 (46%), Gaps = 37/219 (16%)
Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
A+ K + QE +++ E E QL++++ + DL S+N ++ +L+ ++
Sbjct: 665 AIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKR 724
Query: 82 FEV--QHSEGY-RQISALEDDLAQTKAIKDQLQKYI----RELEQANDDL-------ERA 127
+E+ + EGY R+I++L + + A + ++ I ++L AN+ L E
Sbjct: 725 YEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENL 784
Query: 128 KRATIMSLEDFEQRLNQAIE--------RNAFL-----------ESELDEKENLLESVQR 168
K+ M L+ E RL+Q E +N L SE + K+ L +++
Sbjct: 785 KKEKEM-LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEK 843
Query: 169 LKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQ 207
L+ E L+++L + + + R + +++ + DT Q
Sbjct: 844 LEHEISHLKKKL---ENEVEQRHTLTRNLDVQLLDTKRQ 879
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/162 (27%), Positives = 77/162 (47%), Gaps = 28/162 (17%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
+EL Q+ + +++ +++E RDL+ N RL ELE + E +
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTE-----------DV 145
Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE----RN 149
L + L ++ K +LQ + EL QA+D +S++ E+RL Q E +N
Sbjct: 146 KRLNEKLKESNTTKGELQLKLDEL-QASD----------VSVKYREKRLEQEKELLHSQN 194
Query: 150 AFLESELDEKENLLESVQRLK-DEARDLRQELAVQQKQEKPR 190
+L +EL K + L ++ R K +E +L+ L +K+E R
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLE-NKKEEVSR 235
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/145 (22%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 35 ELREFQEGSREYEAELETQLQQIETRNR-------DLLSENNRLRMELETIKEKFEVQHS 87
EL+ E +E + LE Q+ ++T N DLL++ + + +++EKF + +
Sbjct: 221 ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELN 280
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ--- 144
+ + + ++A ++L + + EL + + A +A L + EQ +Q
Sbjct: 281 AHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 340
Query: 145 -AIERNAFLESELDEKENLLESVQR 168
+E+ LE EL+ +LL + +R
Sbjct: 341 EMLEKIGRLEKELENANDLLSATKR 365
Score = 36.6 bits (83), Expect = 0.032
Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 7 TFSSEEEEANYWKDLAMTYK---QRAENTQEELREFQEGSREY---EAELETQLQQIET- 59
T + EE EA +DL T + Q E E+++ E +E + EL+ +L +++
Sbjct: 114 TRTKEELEAEK-RDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS 172
Query: 60 ------------RNRDLL-SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI 106
+ ++LL S+N L EL+T ++ E +I L+ +L K
Sbjct: 173 DVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEE 232
Query: 107 KDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESV 166
+L++ + L+ +N+ L++ +ED +L +A E+ A +E + + N +
Sbjct: 233 VSRLEEQMNGLKTSNEHLQK-------HVEDLLTKLKEAKEQQASMEEKFHNELNAHIKL 285
Query: 167 QRLKDEARD 175
L A D
Sbjct: 286 SNLYKSAAD 294
Score = 36.6 bits (83), Expect = 0.032
Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 12/188 (6%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS---REYEAELETQLQQI 57
+E + EE + + + E +E++ QE + + + LE +++
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489
Query: 58 ETRNRDLLSENNRLRMELETIKEKFEVQHSE-GYRQISALEDDLAQ-------TKAIKDQ 109
E + +DL + L MELE + ++ E IS+ + ++Q + ++ Q
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549
Query: 110 LQKYIRELEQANDDLERAKRATIMS-LEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168
Q+ + L + + ER ++ T S + + + +L A+ L + L++S+ R
Sbjct: 550 NQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVR 609
Query: 169 LKDEARDL 176
+D R L
Sbjct: 610 QRDMYRIL 617
Score = 36.6 bits (83), Expect = 0.032
Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
+S EE N K + ++ E +E EFQ + E+E + Q+++ R +
Sbjct: 970 TSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESM 1029
Query: 69 NRLRMELETIKEKFEVQHSEGYRQIS--------ALEDDLAQTKAIKDQLQKYIRELEQA 120
+ EL+ + + E ++ S A D Q K + KY REL
Sbjct: 1030 EQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLH 1089
Query: 121 NDDLE--RAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRLKDE 172
D+E +A + + + Q L + ++ ES+L E K + E + LKDE
Sbjct: 1090 AADVEALQAAKEQVSKMASVRQHLEETTQK---AESQLLECKASWEERERMLKDE 1141
Score = 36.2 bits (82), Expect = 0.042
Identities = 38/153 (24%), Positives = 68/153 (44%), Gaps = 8/153 (5%)
Query: 38 EFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALE 97
+F+ S + E+E +L + R + E LR+ELE + + + +E +++ +
Sbjct: 45 KFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKAL-TEKNKELEIAQ 103
Query: 98 DDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE---DFEQRLNQAIERNAFLES 154
D + AI+ Q + ELE DL R LE + +RLN+ ++ + +
Sbjct: 104 D---RNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKG 160
Query: 155 ELDEK-ENLLESVQRLKDEARDLRQELAVQQKQ 186
EL K + L S +K + L QE + Q
Sbjct: 161 ELQLKLDELQASDVSVKYREKRLEQEKELLHSQ 193
Score = 32.7 bits (73), Expect = 0.47
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 13/133 (9%)
Query: 55 QQIETRNRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISALEDDLAQTKAIKDQLQK 112
Q++E R+L + L E E ++ K QH E ++ + + K ++++ ++
Sbjct: 1226 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER 1285
Query: 113 YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
++L+Q + R I+ L++ L+ E++ L++ EK+ L E V+R K
Sbjct: 1286 LEQDLQQMQAKV-RKLELDILPLQEANAELS---EKSGMLQA---EKKLLEEDVKRWK-- 1336
Query: 173 ARDLRQELAVQQK 185
AR+ Q L QQK
Sbjct: 1337 ARN--QHLVSQQK 1347
Score = 30.4 bits (67), Expect = 2.3
Identities = 28/159 (17%), Positives = 64/159 (40%), Gaps = 12/159 (7%)
Query: 40 QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99
+ E + L +Q++++E L + + T+ +VQ + RQ+ +
Sbjct: 827 ERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNL 886
Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
TK + QK I L+Q ++E + QR + N ++
Sbjct: 887 HLNTKELLKNAQKEIATLKQHLSNME------VQVASQSSQRTGKGQPSNK------EDV 934
Query: 160 ENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
++L+ +++ +++ DL++ L + M +S+E
Sbjct: 935 DDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE 973
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
E Q+E+ + E SR EL+ QL + + +NR L+E R E EK + +
Sbjct: 951 EKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKM 1010
Query: 90 YRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERN 149
++ +E++L + +D+ + LEQ DLE A +D + + Q ++
Sbjct: 1011 QDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070
Query: 150 AFLESELDEKEN----LLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203
+ LE EL+E+ N L E + R +++ LR EL ++ + S+E + D
Sbjct: 1071 SQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKD 1128
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/228 (26%), Positives = 97/228 (42%), Gaps = 12/228 (5%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
MED E EE DL R+ E+LR R +LE +E +
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
N+DL S L + KE VQ +I+ LED L + + LQ R LE+
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQME---ARIAELEDRLESEERDRANLQLSNRRLERK 1182
Query: 121 NDDLERAKRATIMSLEDFEQRLN---QAIERNA-FLESELDEKENLLESVQRLKDEARDL 176
+L +SL D + +L+ +A++R E E+D E+ + +QR +E D+
Sbjct: 1183 VKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDM 1242
Query: 177 RQELAVQ---QKQEKPRTPMPSSVEAERTDTAVQAT--GSVPSTPIAH 219
+ L Q K++ +PS V + D +T GS+ P+++
Sbjct: 1243 NEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSY 1290
Score = 47.4 bits (111), Expect = 2e-05
Identities = 45/181 (24%), Positives = 91/181 (50%), Gaps = 19/181 (10%)
Query: 28 RAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84
+A N+ E+++ E + AEL+ QLQ +++ E R+R LE ++
Sbjct: 601 QACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRS---- 656
Query: 85 QHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144
QH+E + S L+ L +++ +L+K + EL Q +ER + T + D + +L++
Sbjct: 657 QHNEKVEENSTLQQRLEESEG---ELRKNLEELFQVK--MEREQHQT--EIRDLQDQLSE 709
Query: 145 A-IERNAFLESELDEKENLLESVQRLKDEARDL----RQELAVQQKQEKPRTPMPSSVEA 199
E ++ SE EK L+E + + K + +DL ++ + +K+E+ T + +++
Sbjct: 710 MHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKE 769
Query: 200 E 200
E
Sbjct: 770 E 770
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 25/193 (12%)
Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELETIKEKFE 83
E EL+ +E E +E + T +D R+++ +L+ E+ E
Sbjct: 783 EQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELE 842
Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA-------NDDLERAKRATIMSLE 136
+ ++ RQI L+ D A+ K + + IR+LE+A + A+RA LE
Sbjct: 843 RRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELE 902
Query: 137 DFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ-----EKPRT 191
+ L+Q + L +L E ES Q K++ R L+ E+ ++ EK +
Sbjct: 903 AAQGNLSQTTQEQKQLSEKLKE-----ESEQ--KEQLRRLKNEMENERWHLGKTIEKLQK 955
Query: 192 PMPSSVEAERTDT 204
M VEA RT T
Sbjct: 956 EMADIVEASRTST 968
Score = 45.1 bits (105), Expect = 9e-05
Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Query: 40 QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99
Q+ +E + L+++ +++ + + EN+ L+ LE + + E ++ E
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
+ + ++DQL + EL+ A +R K A I L +Q L + E L ++
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 160 ENLLESVQ-RLKDEARDLRQEL-AVQQKQEKPRTPMPSSVEAERTDTAVQATGS 211
E L +++ LK+E QE+ ++++ + + SVE + V A+ S
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRS 810
Score = 38.9 bits (89), Expect = 0.007
Identities = 39/184 (21%), Positives = 81/184 (44%), Gaps = 6/184 (3%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
++R EELR E + L+ +L++ E R L E +++ME +E+ + +
Sbjct: 644 RERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKME----REQHQTE 699
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQ-KYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144
+ Q+S + D+L K +D+ + I EL QA DL+ A + +R +
Sbjct: 700 IRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERE 759
Query: 145 AIERNAFLESELDEKENLLESVQRLKD-EARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203
L+ E+ + ++ ++ D E + LR+ + K + ++ E ++
Sbjct: 760 LTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAG 819
Query: 204 TAVQ 207
T ++
Sbjct: 820 TEMR 823
Score = 37.7 bits (86), Expect = 0.015
Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 43/198 (21%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
M+D + E + +D A+T +Q E T ++L EYE E ++ L+
Sbjct: 1010 MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDL--------EYELEAKSHLKD---- 1057
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
+ +RL ++E + E++ E L + +++++ +QL+ + + A
Sbjct: 1058 ------DRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAA 1111
Query: 121 NDDLERAK----------RATIMSLE------------DFEQRLNQAIERNAFLESELDE 158
DLE K ++ I+ LE E R+ + +R LESE +
Sbjct: 1112 RQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR---LESEERD 1168
Query: 159 KENLLESVQRLKDEARDL 176
+ NL S +RL+ + ++L
Sbjct: 1169 RANLQLSNRRLERKVKEL 1186
Score = 33.5 bits (75), Expect = 0.27
Identities = 31/171 (18%), Positives = 71/171 (41%), Gaps = 4/171 (2%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
EEL + ++ ++ E Q + R R+L + L+ E+ + ++ + + ++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789
Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
AL + + + + L EQ E + E + R + R A L+
Sbjct: 790 QALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQ 849
Query: 154 SELD----EKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200
+++ ++ E++++ + E R L + L +K+EK ++E E
Sbjct: 850 RQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE 900
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 20/231 (8%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61
+D + +EE+A + L +++ QE L+ ++ R+ E E + ++ E R
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ-LQKYIRELEQA 120
R++ E RL+ LE +DD K + LQK +R+ E+
Sbjct: 487 REMAKEAKRLKEFLEDY------------------DDDRDDPKYYRGSALQKRLRDREKE 528
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ ER ++ LE+ QRL + E + E+E ++K E +E
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588
Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTP-IAHRGPSSSLNTPG 230
Q+K+EK PM E E+ + S P ++ +++ NTPG
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPG 639
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/229 (24%), Positives = 99/229 (43%), Gaps = 23/229 (10%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQ--------EGSREYEAELETQLQQIETRNR 62
EEE+ K+ K+R E +E RE + E RE E E E + ++ R+R
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 63 DLLSENNRLR---MELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
D E +R R + + +E+ ++ + R D + + +++ ++ RE E+
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411
Query: 120 AND---DLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD----E 172
+ + ER + D E+ A ER LE +L EKE + +RLK+ E
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRK-LERKLREKEAAYQ--ERLKNWEIRE 468
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRG 221
+ R+ +++E+ R M + EA+R ++ P +RG
Sbjct: 469 RKKTREYEKEAEREEERRREM--AKEAKRLKEFLEDYDDDRDDPKYYRG 515
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 57.8 bits (138), Expect = 1e-08
Identities = 42/171 (24%), Positives = 92/171 (53%), Gaps = 21/171 (12%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS---ENNRLRMELETIKEK- 81
K+R+ QEEL ++ + R+ E +T IE ++R L S ENN L+ ELE ++E+
Sbjct: 821 KERSSKLQEELDKYSQALRKNEILRQT----IEEKDRSLGSMKEENNHLQEELERLREEQ 876
Query: 82 ---FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
V + ++ L +++Q IK+ L++ I+ ++ +D ++K + SL++
Sbjct: 877 SRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQ 936
Query: 139 EQRLNQ---------AIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
++ +++ A FLE + +E ++L ++++++K + + RQ++
Sbjct: 937 KKEMDEFRYQHEQMNATHTQLFLEKD-EEIKSLQKTIEQIKTQLHEERQDI 986
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/130 (21%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
Query: 11 EEEEANYWKD-LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
E +E Y + + T+ Q EE++ Q+ + + +L + Q I+T N D+ E
Sbjct: 939 EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETK 998
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129
+ +E EK ++ +E R + +++ + K + ++ ++++Q + D E K
Sbjct: 999 VQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKD-EVGKL 1057
Query: 130 ATIMSLEDFE 139
I+ +D E
Sbjct: 1058 TQIIQQKDLE 1067
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/204 (20%), Positives = 92/204 (45%), Gaps = 16/204 (7%)
Query: 6 KTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLL 65
+T+ +E E ++ M + + E +E + +E Q ++ + +
Sbjct: 1470 ETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFE-------QLLKEKEQGKT 1522
Query: 66 SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
E N+L +++++EK V E + + AL+ + A+++++Q+ + ++N +LE
Sbjct: 1523 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1582
Query: 126 RAKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESV-QRLKDEARDLR 177
R + + S + + + A +R A LE +L N +E+ + + L+
Sbjct: 1583 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQ 1642
Query: 178 QELAVQQKQEKPRTPMPSSVEAER 201
++L V KQ + T + SV E+
Sbjct: 1643 EQLNVVSKQ-RDETALQLSVSQEQ 1665
Score = 42.4 bits (98), Expect = 6e-04
Identities = 39/163 (23%), Positives = 81/163 (49%), Gaps = 4/163 (2%)
Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK 79
DL + + + + + + E + E E EL+ Q Q+ + + ++ + E ++I
Sbjct: 471 DLRLNLEAKEQELNQSISEKETLIAEIE-ELDRQNQEATKHMILIKDQLSKQQNEGDSII 529
Query: 80 EKFEVQHSEGYRQISALEDD-LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
K + ++ +++ LEDD + TK + Q +K I+ E A +DL K+ +E+
Sbjct: 530 SKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQS-EVALNDLHLTKQKLEDKVENL 588
Query: 139 EQRLNQAIERNAFLESE-LDEKENLLESVQRLKDEARDLRQEL 180
+LN++ E N ++ E L+ KE++ ++ + L +L Q L
Sbjct: 589 VDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSL 631
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 18/161 (11%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
EE ++++ E ++ + L+ N + ME+ +K+ E ++
Sbjct: 734 EEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETK 793
Query: 94 SALEDDLAQTKAIKDQLQK---YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150
L L + K + + K +I +L++ + L+ E+ + + +QA+ +N
Sbjct: 794 DVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQ----------EELD-KYSQALRKNE 842
Query: 151 FLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRT 191
L ++EK+ L S +K+E L++EL + ++E+ RT
Sbjct: 843 ILRQTIEEKDRSLGS---MKEENNHLQEELE-RLREEQSRT 879
Score = 39.7 bits (91), Expect = 0.004
Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 8/88 (9%)
Query: 41 EGSREYEAEL-ETQLQQIETRNRDLLSENNRLRMELETIKEKFEV------QHSEGYR-Q 92
EG+ E EAEL +++ ++IE + L SEN RL+ ++EK E Q S YR Q
Sbjct: 40 EGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQ 99
Query: 93 ISALEDDLAQTKAIKDQLQKYIRELEQA 120
+ E +++ KA + LQ + +L+ A
Sbjct: 100 LQQKEVEISHLKARQIALQDQLLKLQSA 127
Score = 37.4 bits (85), Expect = 0.019
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 26/170 (15%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
+E E Q + E E ++ TR+ L SE + LR+ LE +++ SE I
Sbjct: 436 QEKEELQMSLLKLNNEYEV-IKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLI 494
Query: 94 SALEDDLAQTK-------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
+ +E+ Q + IKDQL K E + L++ L D ++R++Q
Sbjct: 495 AEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQ-------DLNDEKKRVHQLE 547
Query: 147 ERNAFLESELD-EKENLLES----------VQRLKDEARDLRQELAVQQK 185
+ + ELD +KE L++S Q+L+D+ +L +L Q+
Sbjct: 548 DDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQE 597
Score = 35.4 bits (80), Expect = 0.072
Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 26/160 (16%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
E L E E ++ EL LQ+ + R L N+RL + E +H +
Sbjct: 1336 EVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQ----- 1390
Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSL-EDFEQRLN------QAI 146
+ ++ Q K +D LQK ++E D L +AK ++S E+F ++N QA+
Sbjct: 1391 --TDSEIKQLKEKQDVLQKLLKE----KDLLIKAKSDQLLSSNENFTNKVNENELLRQAV 1444
Query: 147 ----ERNAFLESEL----DEKENLLESVQRLKDEARDLRQ 178
ER LE ++ E E ++E+ + + E + L++
Sbjct: 1445 TNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQE 1484
Score = 35.0 bits (79), Expect = 0.094
Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 38/197 (19%)
Query: 12 EEEANYWKDLAMTYKQRA--------------------ENTQEELREFQEGSREYEAELE 51
E E +W+ +A T K + +N +E+ + Q + +
Sbjct: 185 ESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQ 244
Query: 52 TQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111
+L +I R+R+ LS+ ELE + + Q G +E DL++ ++Q
Sbjct: 245 QKLTEISRRHREELSDYEERIEELENLLQ----QGGSG-----VIETDLSKIY----EMQ 291
Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELD----EKENLLESVQ 167
K I+ L+ + + ++D ++L+ A L E + EK ++E +
Sbjct: 292 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECE 351
Query: 168 RLKDEARDLRQELAVQQ 184
LK E L Q AV+Q
Sbjct: 352 NLKLECSKL-QPSAVKQ 367
Score = 28.9 bits (63), Expect = 6.8
Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 34/203 (16%)
Query: 31 NTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK----------E 80
N EEL + ++ ++ ++E QQ+ T +++ E+ +L+ EL ++
Sbjct: 1202 NQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNS 1261
Query: 81 KFEVQHS---EGYRQ----ISALEDDLAQTKAIKDQL----QKYIRELEQANDDLERAKR 129
K +V ++ + Y Q + +LAQ + QL + +L+ + L A
Sbjct: 1262 KLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASL 1321
Query: 130 ATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLE----SVQRLKDEARDLRQELAVQQ 184
T S E ++ + E + L+ EL+E L+ +++ L++ L +A
Sbjct: 1322 LTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATS 1381
Query: 185 KQEKPRTPMPSSVEAERTDTAVQ 207
+ E+ E E+TD+ ++
Sbjct: 1382 ELERK--------EHEQTDSEIK 1396
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 56.2 bits (134), Expect = 4e-08
Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 28/195 (14%)
Query: 19 KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68
K ++ Y + + + E RE + E + E +AELE +Q T DL+S
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
Query: 69 NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117
+ + ELE K E Q E Q+ LED+L T+ K +L+ ++ R+L
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
Query: 118 EQANDDLERAKRATIMS-------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170
+ ++ E K+ + LED ++ + A+ LE +L + E ++S + +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
Query: 171 DEARDLRQELAVQQK 185
DEA ++L Q K
Sbjct: 1634 DEAIKQLRKLQAQMK 1648
Score = 49.3 bits (116), Expect = 5e-06
Identities = 46/204 (22%), Positives = 92/204 (45%), Gaps = 6/204 (2%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
EEEA + +Q+ EEL E E ++ +A LE Q +E +L +E L
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+ + E ++K E Q E Q+ E + +T+ + D++ K EL+ L ++
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQE--LQVKFNEGERVRTE-LADKVTKLQVELDNVTGLLSQSD 1293
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
+ +DF +Q + L+ E +K +L +++++DE R++L +++ +
Sbjct: 1294 SKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH 1353
Query: 189 PRTPMPSSVEAERTDTAVQATGSV 212
+++ A+ D + SV
Sbjct: 1354 NLEKQIATLHAQVADMKKKMEDSV 1377
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 27/207 (13%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+E K F +E E+ KD E ++ L + E + ELE +LQ E
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE-- 1552
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
RL + L+ +K +FE R + ++ Q++ K QL + +RE+E
Sbjct: 1553 -----DAKLRLEVNLQAMKAQFE-------RDLQGRDE---QSEEKKKQLVRQVREMEAE 1597
Query: 121 NDDLER-------AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
+D + A++ M L+D E ++ A + +L + + ++ R D+
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
Query: 174 RDLRQELAVQQKQEKPRTPMPSSVEAE 200
R R+E+ Q K+ + + S+EAE
Sbjct: 1658 RASREEILAQAKENEKKL---KSMEAE 1681
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 16/192 (8%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE------AELETQLQQIETRNRDLL 65
EEE +D + + ++ + EF E E A+L+ + + + T + L
Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 66 SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
+ R ELE + K E ++ QI+ L+ +A+ +K QL K EL+ A +E
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE---LKMQLAKKEEELQAALARVE 1093
Query: 126 RAKRATIMSLEDFEQRLNQAIERNAFLESEL-------DEKENLLESVQRLKDEARDLRQ 178
M+L+ + +Q E LESE +K +L E ++ LK E D
Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153
Query: 179 ELAVQQKQEKPR 190
A QQ+ R
Sbjct: 1154 STAAQQELRSKR 1165
Score = 45.4 bits (106), Expect = 7e-05
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET-- 59
+D GK+ E+ + K + E ++EL+ ++ E L+ Q E
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
Query: 60 RNRDLLSENNRLRM-----ELETIKEKFEVQHSEGYRQISALEDDLAQTKAI-------K 107
+ RD SE + ++ E+E E Q S LE DL +A +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
D+ K +R+L+ D R T S E+ + + ++ +E+E+ + + L + +
Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
Query: 168 RLKDEARDLRQELA 181
R K +A+ R ELA
Sbjct: 1694 RAKRQAQQERDELA 1707
Score = 42.0 bits (97), Expect = 8e-04
Identities = 42/201 (20%), Positives = 93/201 (46%), Gaps = 29/201 (14%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK---F 82
++R ++ Q E ++ Q+ +E LE QL++ E+ + L E +L+ ++E+
Sbjct: 928 EERCQHLQAEKKKMQQNIQE----LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 83 EVQHSEGYRQISALEDDLAQ---------------------TKAIKDQLQKYIRELEQAN 121
E Q+ + ++ LED +A+ +A+ L++ +R E+
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 122 DDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE-SVQRLKDEARDLRQEL 180
+LE+ +R D ++ + + A L+ +L +KE L+ ++ R+++EA L
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 181 AVQQKQEKPRTPMPSSVEAER 201
++ E + + +E+ER
Sbjct: 1104 KKIRELESQISELQEDLESER 1124
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 26 KQRAENTQEELREFQEGSR-EYEAELETQLQQIETRNRDLLSEN---NRLRMELETIKEK 81
+ +AE + +L E E + E E L++ Q E R++ N L E +T + +
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186
Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
+ + + + L + L QTK +K L+K + LE +L + + D E +
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246
Query: 142 LNQAIERNAFLESELDEKE----NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSV 197
+ + L+ + +E E L + V +L+ E ++ L+ + T S++
Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306
Query: 198 EAERTDT 204
E++ DT
Sbjct: 1307 ESQLQDT 1313
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 10/170 (5%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+Q E T+ +L + AEL+ Q+ +++ + L + L+ L ++E+ +
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ---LAKKEEELQAALARVEEEAAQK 1099
Query: 86 HS------EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
+ E QIS L++DL +A +++ +K R+L + + L+ T+ S +
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 140 QRLNQAIERNAFLESELDEKENLLES-VQRLKDEARDLRQELAVQQKQEK 188
+ ++ + L+ L+E+ E+ +Q ++ + +ELA Q +Q K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209
Score = 40.8 bits (94), Expect = 0.002
Identities = 61/302 (20%), Positives = 119/302 (39%), Gaps = 29/302 (9%)
Query: 30 ENTQEELREFQEGSREYEAE---LETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
E + +E ++ + EAE L+ +L E R E + L E+ K +
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721
Query: 87 SEGYR---QISALEDDLAQ----TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
E R +I+ LE++L + T+ I D+L+K +++Q N DL +R+ E+
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL-NLERSHAQKNENAR 1780
Query: 140 QRLNQAIERNAFLESELDEKENLLE-----SVQRLKDEARDLRQELAVQQKQEKPRTPMP 194
Q+L + +N L+ +L E E ++ S+ L+ + L ++L + K+ +
Sbjct: 1781 QQLER---QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQV 1837
Query: 195 SSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISAL 254
E + D +Q + + +R L+++ A+R
Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897
Query: 255 NIVGDLLRKVGALESKLASCRNLVYDQS-----PNRTGGPASGRSSKNR-----DGGERR 304
+ D A+ +++S +N + P R +G S DG E +
Sbjct: 1898 RELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK 1957
Query: 305 PS 306
P+
Sbjct: 1958 PA 1959
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 8/128 (6%)
Query: 43 SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102
SR+ E + + + ++ R + L +EN E+ET++ + + + Q+ A + A+
Sbjct: 841 SRQEEEMMAKEEELVKVREKQLAAENRLT--EMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 103 TKAIKDQLQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
+ ++ +L +ELE+ DLE + L+ ++++ Q I+ LE +L+E+
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQE---LEEQLEEE 955
Query: 160 ENLLESVQ 167
E+ + +Q
Sbjct: 956 ESARQKLQ 963
Score = 38.9 bits (89), Expect = 0.007
Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 19/198 (9%)
Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
+G S+ + + KD + Q ++TQE L+E + L T+L+Q+E
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQ-LQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340
Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
R+ L E + LE Q ++ +++ L + +K +LQK + L Q
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLK 170
A D LE+ K L+D L+ + LE + + + LL +++
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1460
Query: 171 DEARDLRQELAVQQKQEK 188
E RD R E ++K+ K
Sbjct: 1461 AEERD-RAEAEAREKETK 1477
Score = 37.7 bits (86), Expect = 0.015
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 25/194 (12%)
Query: 14 EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAE---LETQLQQIETRNRDL---LSE 67
+ ++ + A +++ + + L E + S +Y E E + ++ ET+ L L E
Sbjct: 1428 DLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE 1487
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
+ ELE + ++F + +ED ++ KD + K + ELE++ LE+
Sbjct: 1488 AMEQKAELERLNKQFRTE----------MEDLMSS----KDDVGKSVHELEKSKRALEQQ 1533
Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187
LE+ E L + LE L + E + +DE + +++ V+Q +E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 188 KPRTPMPSSVEAER 201
M + +E ER
Sbjct: 1594 -----MEAELEDER 1602
Score = 33.9 bits (76), Expect = 0.21
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 49/206 (23%)
Query: 21 LAMTYKQRAE----NTQEELREFQEGSREYEAELETQLQQIETRNRDL--------LSEN 68
LA+ K+R E +EEL E Q + L+ QI+ N DL +EN
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 69 NRLRMELETIKEKFEVQHSEG-----YR-QISALEDDLAQT------------------- 103
R ++E + + K ++Q EG Y+ I+ALE +AQ
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
Query: 104 ---KAIKD---QLQKYIRELEQANDDLERAK---RATIMSLEDFEQRLNQAIERNAFLES 154
K +KD Q+ R EQ D ++A + LE+ E+ +A L+
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898
Query: 155 ELDEKENLLESVQRLKDEARDLRQEL 180
EL E+ E+ + E L+ +L
Sbjct: 1899 EL---EDATETADAMNREVSSLKNKL 1921
Score = 31.6 bits (70), Expect = 1.0
Identities = 16/72 (22%), Positives = 34/72 (47%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
++D + +++A+ K++ E +EE + R+ + ELE + +
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910
Query: 61 NRDLLSENNRLR 72
NR++ S N+LR
Sbjct: 1911 NREVSSLKNKLR 1922
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 56.2 bits (134), Expect = 4e-08
Identities = 77/337 (22%), Positives = 134/337 (39%), Gaps = 61/337 (18%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
E + + KDL ++ Q E RE + ++E E QLQ+ + R L
Sbjct: 316 EGKTSLHKDLKQKRRE-----QREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEA 370
Query: 72 RMELETIKEKFEVQHSEGYRQIS-ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ + E + ++ E + +R++ ALE L + + + +Q E+E ++ R +R
Sbjct: 371 QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQA---EMELKEEEAAR-QRQ 426
Query: 131 TIMSLEDFEQRLNQAIE---------------RNAFLESELDEKENLLE-------SVQR 168
I LE+ +QRL +A++ + LE E ++ + L++ ++R
Sbjct: 427 RIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIER 486
Query: 169 LKDEARDLRQELA-----VQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPS 223
+ E +L+QE+A +QQ Q++ + A+ A Q ST + H
Sbjct: 487 AQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQ 546
Query: 224 SSL----NTPGSFRRGLDDS-TGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLV 278
+ PG R S +G P A R S+L R
Sbjct: 547 MNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLK-------------------RLTR 587
Query: 279 YDQSPNRTGGPASGRSSKNRDGGERRPSSTSVPLGDK 315
+ NRT P S K+ +GG+ P+ S P DK
Sbjct: 588 WGSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDK 624
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.8 bits (133), Expect = 5e-08
Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 9/178 (5%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+EEE + +++ +E LRE + RE E ++ Q +++ + ++L +
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
LR + E +++ ++Q E E Q + +++Q +K R+ E+ + E+ R
Sbjct: 337 LREQKELREQEEQMQEQE--------EKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMRE 387
Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
+ D E+R+ + ER E + E+E + E V+++++E + QE + ++EK
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Score = 48.9 bits (115), Expect = 6e-06
Identities = 31/180 (17%), Positives = 91/180 (50%), Gaps = 10/180 (5%)
Query: 10 SEEEEANYW-KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
++E+E W ++ M ++R ++++RE +E RE E +++ Q ++++ + + +
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+++ + E + E+ E + E+ + + + + +Q +K + + + +
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQ--------EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
I E E++ Q E+ + + ++ E+E++ E +++++E +R++ Q+QE+
Sbjct: 683 EEKIWEQEKMEKK-TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Score = 48.5 bits (114), Expect = 8e-06
Identities = 41/191 (21%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61
E GK E+E W+ ++R ++ELRE ++ RE + EL Q +Q++ +
Sbjct: 304 EQEGKM---REQEEKMWRQ-----EKRLREQEKELREQEKELRE-QKELREQEEQMQEQE 354
Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
+ + ++R + +EK Q + Q + + Q + ++DQ ++ + E+
Sbjct: 355 EKMWEQEEKMREQ----EEKMWRQEERLWEQEKQMRE---QEQKMRDQEERMWEQDERLR 407
Query: 122 DDLERAKRATIM--SLEDF--EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
+ ER + M +E E+++ + ++ E ++ E+E + E +++++E +R
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 178 QELAVQQKQEK 188
++ QKQE+
Sbjct: 468 EQEEKMQKQEE 478
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/195 (18%), Positives = 95/195 (48%), Gaps = 9/195 (4%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
M++ + +EE+ ++ ++R ++++RE ++ R+ E + Q +++ +
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
+ + E ++ ++E ++E+ ++Q E ++ E+ + + + I+++ +K E E
Sbjct: 410 -EERMREQEKMWEQVEKMREEKKMQEQE--KKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 121 NDDLERAKRATIMSLEDFE-----QRLNQAIERNAFLESELDEKENLLESVQRLKDEARD 175
+ E+ ++ E E QRL + E+ E +++E + E ++++D+
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526
Query: 176 LRQELAVQQKQEKPR 190
QE + +QEK R
Sbjct: 527 WGQEKKM-WRQEKMR 540
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/184 (21%), Positives = 86/184 (46%), Gaps = 6/184 (3%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENN 69
E+E+ ++ M ++R ++++RE +E RE E +++ Q + + E ++ +
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAK 128
+ E +EK + Q + + Q + D K Q+ +RE E + E
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 129 RATIMSLEDFEQRLN---QAIERNAF-LESELDEKENLLESVQRLKDEARDLRQELAVQQ 184
R + D E+R+ Q E+ + E ++ E+E + E +++++E +R++ Q
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 185 KQEK 188
+QE+
Sbjct: 614 EQEE 617
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/185 (17%), Positives = 85/185 (45%), Gaps = 6/185 (3%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
++E+E W M ++ ++++RE +E RE E +++ Q ++++ + ++ +
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Query: 70 RLRMELETIKEKFEVQHSE----GYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
++ + E + E+ + + + ++ E Q + ++DQ +K + E+ E
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Query: 126 RAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185
+ + E+ Q + E ++E + E +Q +++ R+ QE ++ +
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE--QEEKMRGQ 873
Query: 186 QEKPR 190
+EK R
Sbjct: 874 EEKMR 878
Score = 35.4 bits (80), Expect = 0.072
Identities = 37/187 (19%), Positives = 86/187 (45%), Gaps = 25/187 (13%)
Query: 12 EEEANYWKDLAM------TYKQRAENTQEELREFQEGSREYE-AELETQLQQIETRNRDL 64
E+E W+ + ++ QE+++E +E E E E +TQ Q+ +T +++
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708
Query: 65 LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124
+ E +R + ++E+ E+ + + E Q + + +Q +K + E+ +
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE-- 766
Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQ 183
+QRL + E+ + ++ E+E + E ++++D+ +R QE ++
Sbjct: 767 --------------QQRLPEQKEK-LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 184 QKQEKPR 190
++EK R
Sbjct: 812 GQEEKMR 818
Score = 35.0 bits (79), Expect = 0.094
Identities = 40/180 (22%), Positives = 82/180 (45%), Gaps = 16/180 (8%)
Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72
EE +D R T EEL++ AEL+ +L E SE + ++
Sbjct: 200 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLPLAE-------SEKSEIQ 245
Query: 73 MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+ ++ +K K E + Q + L++++ + + + +K IR+ E+ E R
Sbjct: 246 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 305
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190
+ + E+++ + +R E EL E+E L + L+++ ++ QE + +++EK R
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 55.1 bits (131), Expect = 9e-08
Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 46/222 (20%)
Query: 12 EEEANYWKDLAMTYKQRAENTQ---EELREFQEGS-----------------REYEAELE 51
E + N KD K+R +N+Q E++ + Q R+ +AE
Sbjct: 530 ENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESS 589
Query: 52 TQLQQIETRNRDL-----LSENNRLRMELETIKEKFEVQHSEGYR------------QIS 94
Q+QQ+E+ NRDL L E +L++E E I + ++ R +I
Sbjct: 590 KQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRIC 649
Query: 95 ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR----ATIMSLEDFEQRLNQAIERNA 150
LE+DL K + +++ R+L++ DLE+ K L+ +Q L Q +
Sbjct: 650 GLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHK 709
Query: 151 FLESELDEKENLLESVQRLKDEA-----RDLRQELAVQQKQE 187
++ L +K + ES++ K EA + L +E ++QK E
Sbjct: 710 ATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVE 751
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 7 TFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQ-------IET 59
T E++ + M K E ELR+ ++ + EL+ QL+ +T
Sbjct: 819 TLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT 878
Query: 60 RNRDL---LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
+ R+L E +L EL+ K++ + + R A + ++ TKA +QL + I
Sbjct: 879 QVRELKEECEEKTKLGKELQQKKQELQDE-----RDSLAAQLEITLTKADSEQLARSI-- 931
Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLESVQRLKDEARD 175
E+ DLE+ K + +++ R Q + E++A + S + L V L +E +
Sbjct: 932 AEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEE 991
Query: 176 LRQELAVQQKQ 186
L +L Q+Q
Sbjct: 992 LNNKLKDVQEQ 1002
Score = 42.7 bits (99), Expect = 5e-04
Identities = 40/167 (23%), Positives = 79/167 (47%), Gaps = 29/167 (17%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+Q A+ +EL++ E + + +TQ++++ ++ E +L EL+ K++ + +
Sbjct: 852 RQDADGQMKELQDQLEAEQYFSTLYKTQVREL----KEECEEKTKLGKELQQKKQELQDE 907
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA------------------ 127
R A + ++ TKA +QL + I E + ++ + E+
Sbjct: 908 -----RDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT 962
Query: 128 -KRATIMSLEDFEQRLNQAIERNAFLESELDEK-ENLLESVQRLKDE 172
K ATI SLE+ + L + A + EL+ K +++ E + RLKDE
Sbjct: 963 EKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDE 1009
Score = 39.7 bits (91), Expect = 0.004
Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
R+ S +R E + I++K ++ A E+ + K++ +L+K +ELE+
Sbjct: 429 RETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEE-E 487
Query: 122 DDLERAKRATIMSLEDFE---QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ 178
L ++ + + LE + Q N +R A + E D+K NL V LKD+ DL++
Sbjct: 488 ITLRKSVESALRQLEREKALLQHKNAEYQRKA--DHEADKKRNLENDVNSLKDQLEDLKK 545
Score = 39.3 bits (90), Expect = 0.005
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 35 ELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQIS 94
E++E ++ E + + +E NR L S+ L E E + K + + Q+S
Sbjct: 949 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLK----DVQEQLS 1004
Query: 95 ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIER-----N 149
L+D+ AIK Q +K + E+ K A IM+ ++ +R N R N
Sbjct: 1005 RLKDEEISAAAIKAQFEKQLL-TERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKEN 1063
Query: 150 AFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQK 185
L EL E+E L + + + + E +++ ++A + +
Sbjct: 1064 RKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQ 1100
Score = 35.0 bits (79), Expect = 0.094
Identities = 39/188 (20%), Positives = 83/188 (44%), Gaps = 9/188 (4%)
Query: 20 DLAMTYKQ--RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET 77
DL M +Q + ++++L++ E + LE Q ++ +D + L+ +LE
Sbjct: 809 DLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEA 868
Query: 78 IKEKFEVQHSEGYR-QISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE 136
E S Y+ Q+ L+++ + + +LQ+ +EL+ D L T+ +
Sbjct: 869 -----EQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKAD 923
Query: 137 DFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPS 195
+ + A E+ + LE E KE + E + R K E + +A ++ + T +
Sbjct: 924 SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVA 983
Query: 196 SVEAERTD 203
++ E+ +
Sbjct: 984 NLANEKEE 991
Score = 31.6 bits (70), Expect = 1.0
Identities = 16/62 (25%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
EN +L MEL++ +EK Q + ++++ ++ +A+ I+ +LQ L+ + D+E+
Sbjct: 1062 ENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQ---MTLDSKDSDIEQ 1118
Query: 127 AK 128
+
Sbjct: 1119 LR 1120
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 55.1 bits (131), Expect = 9e-08
Identities = 50/203 (24%), Positives = 94/203 (46%), Gaps = 30/203 (14%)
Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
T + E +L E E + + +L ++ETR R++ E+ ++EL+ + +
Sbjct: 821 TQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQ 880
Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA--------------NDDLER--- 126
+ E Q++AL+ A A++ QL++ ELE+ D+++R
Sbjct: 881 LSLQERESQLTALQ---AARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFD 937
Query: 127 AKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESVQRLKDEARDLRQE 179
A R + + D E++LNQ E NA +L +LDE + + +L+ E LR+E
Sbjct: 938 ALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRRE 997
Query: 180 LAVQQKQEKPRTPMPSSVEAERT 202
+ ++E T ++EA +T
Sbjct: 998 IT---EREMQLTSQKQTMEALKT 1017
Score = 38.1 bits (87), Expect = 0.011
Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88
AE +E+ RE Q ++ E L+ + Q E + + L ++ + + ET++ + E
Sbjct: 693 AEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEE 752
Query: 89 GYRQISALEDDLAQTKAIKDQ---LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
+ + L + A A+ + L++ I EL +AN + T +++ E+ +++
Sbjct: 753 AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISEL 812
Query: 146 IERNAFLESELDEKE 160
++ +LE++ + E
Sbjct: 813 RQQKFYLETQAGKLE 827
Score = 37.0 bits (84), Expect = 0.025
Identities = 53/214 (24%), Positives = 84/214 (39%), Gaps = 27/214 (12%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
KQR Q +L++ + + + L LQ+ R L +E + L +LE I+ + +
Sbjct: 1149 KQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHE 1208
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
+ IS QTK I + QA D K+ + S + L
Sbjct: 1209 KVKMEGTIS------QQTKLI---------DFLQAKMDQPAKKKKGLFSRRKEDPALPTQ 1253
Query: 146 I-----ERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200
+ E LE E L E++Q+ + E R R+E A ++ + P PS+
Sbjct: 1254 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPH---PSTPATA 1310
Query: 201 RTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRR 234
R A+ A P H+ + SL P S RR
Sbjct: 1311 RQQIAMSAIVRSPE----HQPSAMSLLAPPSSRR 1340
Score = 35.0 bits (79), Expect = 0.094
Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 31/191 (16%)
Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEA---------ELETQLQQIETRNRDLLSENNR 70
+L T + E Q E R+++A +LE QL Q+ N +L ++N
Sbjct: 910 ELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFY 969
Query: 71 LRMEL--------ETIKEKFEVQH-----SEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
L +L E ++ + EV H +E Q+++ + + K L++ + +L
Sbjct: 970 LSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDL 1029
Query: 118 EQANDDL---ERAKRATIMSLEDFEQRLNQAIERNAFLESELD-EKENLLESVQRLKDEA 173
E ND+L ER A L D + + + L+ LD EK++ + QR+ +
Sbjct: 1030 EALNDELLEKERQWEAWRSVLGDEKSQFECRVRE---LQRMLDTEKQSRARADQRITESR 1086
Query: 174 RDLRQELAVQQ 184
+ + ELAV++
Sbjct: 1087 QVV--ELAVKE 1095
Score = 33.5 bits (75), Expect = 0.27
Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 20/148 (13%)
Query: 53 QLQQIETRNRDLLSENNRLRMELETIKEK-FEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111
++ Q + + LL + +L+ IKE+ ++ Q E ++ LE+DL + D +
Sbjct: 527 EVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYE 586
Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD 171
+RE A ++ +R +AT + + +L +A ++ + E+ E L
Sbjct: 587 SELRESRLAAEEFKR--KAT-----ECQHKLLKAKDQG---KPEVGEYAKL--------- 627
Query: 172 EARDLRQELAVQQKQEKPRTPMPSSVEA 199
E + Q+L +Q+ QEK + +S EA
Sbjct: 628 EKINAEQQLKIQELQEKLEKAVKASTEA 655
Score = 32.7 bits (73), Expect = 0.47
Identities = 36/184 (19%), Positives = 88/184 (47%), Gaps = 16/184 (8%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSR----EY------EAELETQLQQIETRN 61
E E + A +K++A Q +L + ++ + EY AE + ++Q+++ +
Sbjct: 586 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 645
Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
+ + L+ I++ E R++ L++ ++ I+ +L + ELE+ +
Sbjct: 646 EKAVKASTEATELLQNIRQAKE----RAERELEKLQNREDSSEGIRKKLVE-AEELEEKH 700
Query: 122 DDLERAKRATIMSLEDFEQRLNQAIE-RNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ + + + + L+ EQ + I+ + ++ +L +KE L +QR ++EA + + L
Sbjct: 701 REAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKIL 760
Query: 181 AVQQ 184
+ Q+
Sbjct: 761 SEQK 764
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/189 (25%), Positives = 89/189 (47%), Gaps = 25/189 (13%)
Query: 13 EEANYWKDLAMTYKQRAENTQE---ELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
E ++ L++ K+ + T + EL+ QE + + E L+QIE +L
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE----NLQETET 570
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129
+LR ELE ++E+ + + E ++ E++ + + KYI EL+Q N L++
Sbjct: 571 QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGT 630
Query: 130 ATIMSLEDFEQRLNQAI-----------ERNAFLESELDEK----ENLLESVQRLK---D 171
A L +E ++N+ E + E+++K ENLLE V++ K D
Sbjct: 631 AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD 690
Query: 172 EARDLRQEL 180
EA L++E+
Sbjct: 691 EAVKLQKEI 699
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/208 (19%), Positives = 88/208 (42%), Gaps = 20/208 (9%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELE-------TQLQQIETRNRD 63
E E+ WK ++ E+ +E R+ E R+ EL+ +L++ N+D
Sbjct: 112 EAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKD 171
Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
L+ ENN R +KE + + E+ + + ++K I E+
Sbjct: 172 LIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQ 231
Query: 124 LERAKRATIMSL-----------EDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
E ++ L +++++ +N ++ + L ++ EKEN ++ + L +E
Sbjct: 232 AENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEE 291
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
+RD +L ++K + + S+E +
Sbjct: 292 SRDKVNQL--EEKTKLQSENLKQSIEKQ 317
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/171 (19%), Positives = 84/171 (49%), Gaps = 12/171 (7%)
Query: 49 ELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKD 108
+L+T+L+ + +N +L S N+L +E + + + + S+ ++ ++D+ K ++
Sbjct: 501 DLKTELENEKLKNTELTSHCNKLSLENKELTQ----ETSDMTLELKNQQEDINNNKKQEE 556
Query: 109 QLQKYIRELE----QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164
++ K I L+ Q ++LE + ++ + +L+++ E L +++ K +E
Sbjct: 557 RMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIE 616
Query: 165 SVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPST 215
+Q+ E + L+++ + KQ + +E E ++A Q G + T
Sbjct: 617 ELQQ---ENKALKKKGTAESKQLNVYEIKVNKLELE-LESAKQKFGEITDT 663
Score = 39.3 bits (90), Expect = 0.005
Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 23/166 (13%)
Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
EN ++L E SR+ +LE + + + + + + L ELE I K +Q S
Sbjct: 279 ENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDI--KVSLQRSVS 336
Query: 90 YRQISALEDDL-AQTKAIKDQLQKYIRELEQANDDLERAKRA----------TIMSLEDF 138
++ ALE+DL TK I ++ ++E++N +A+ A T+ SLE+
Sbjct: 337 TQK--ALEEDLQIATKTICQLTEEKETQMEESN----KARAAHSFVVTEFETTVCSLEEL 390
Query: 139 EQRLNQAIERN----AFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ Q +E+N L EL +K + LE + +L + +EL
Sbjct: 391 LRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/189 (20%), Positives = 84/189 (44%), Gaps = 21/189 (11%)
Query: 33 QEELREFQEGSREYEAELETQLQQI----------ETRNRDLLSENNRLRMELETIKEKF 82
+E+ + Q +EY+ E+ + +Q+ E + +DL R ++ ++EK
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKT 303
Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
++Q + I + + IK LQ+ + + +DL+ A + E+ E ++
Sbjct: 304 KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQM 363
Query: 143 ---NQAIERNAFLESELDE-----KENLLESVQRL---KDEARDLRQELAVQQKQEKPRT 191
N+A ++F+ +E + +E L QRL +D+ + L EL + + + T
Sbjct: 364 EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMT 423
Query: 192 PMPSSVEAE 200
+ ++ E E
Sbjct: 424 KLTNNKEVE 432
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E +
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
SE +I L ++ K L+K R LE +L+ + + D + +
Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286
Query: 146 IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203
+ +LDEKE L+ + R K +EL Q ++E K + + ++++ R D
Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345
Score = 49.7 bits (117), Expect = 4e-06
Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
+EE++ N + +Q+ ++ EGS E E +L L++ + + L
Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
M++E K++ + + + +IS L+ + +A+ QLQK I+EL+ ++L
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
ERA RA LE+ +RL +A IE N E+E + + +L E+
Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189
Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
+ + A LR++ A V+QK EK ++ M ++ A +T +A G
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249
Query: 211 SV 212
++
Sbjct: 1250 NL 1251
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65
+ +EEE N +T K+R ++E E ++ + E A++E + E + ++L
Sbjct: 932 AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985
Query: 66 SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122
E L + + KEK +Q H + + A ED + K +L++ + +LE + +
Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045
Query: 123 -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161
DLERAKR +IM +E+ +Q+L++ +++ F L+S++++++
Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 162 LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211
L +Q R+++ ++ E A + K EK R+ + +E +ER + A AT +
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
++++ N+ K LA +KQ+ E T EL Q+ +R EL E L Q+ET R
Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506
Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
EN L+ E+ + E Q +EG ++I LE K +++EQ +
Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545
Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168
L+ A SLE E + LNQ ++R A + E+D+ K N ++ES+Q
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 169 LKD-EARDLRQELAVQQKQE 187
D E R + +++K E
Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625
Score = 42.0 bits (97), Expect = 8e-04
Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%)
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
E+ T+KE+F+ ++D+LA+++A + +L++ + L + +DL+ +A
Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
L D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Score = 36.2 bits (82), Expect = 0.042
Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60
S EEE+ DL QR Q E EF E EA L +QL QQIE
Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321
Query: 61 NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107
R L E N L R + + ++E++E + +E R +S ++AQ +
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379
Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
KY + Q ++LE AK+ L+ E+ + + A LE ++ Q
Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425
Query: 168 RLKDEARDL 176
RL++E DL
Sbjct: 1426 RLQNEVEDL 1434
Score = 35.0 bits (79), Expect = 0.094
Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82
Q + + + LRE E +E +AEL+ L + T + E + ++ ELE K+K
Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399
Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135
+ + A+ A + K +LQ + +L E+ N L++ +R L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459
Query: 136 EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176
+++Q+ + +NA+ ES LD+ E L + L+ E DL
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518
Query: 177 RQELAVQQKQEKPRTPMPSSVEAERTD 203
+++A K+ + VE E+ +
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E +
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
SE +I L ++ K L+K R LE +L+ + + D + +
Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286
Query: 146 IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203
+ +LDEKE L+ + R K +EL Q ++E K + + ++++ R D
Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345
Score = 49.7 bits (117), Expect = 4e-06
Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
+EE++ N + +Q+ ++ EGS E E +L L++ + + L
Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
M++E K++ + + + +IS L+ + +A+ QLQK I+EL+ ++L
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
ERA RA LE+ +RL +A IE N E+E + + +L E+
Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189
Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
+ + A LR++ A V+QK EK ++ M ++ A +T +A G
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249
Query: 211 SV 212
++
Sbjct: 1250 NL 1251
Score = 48.5 bits (114), Expect = 8e-06
Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65
+ +EEE N +T K+R ++E E ++ + E A++E + E + ++L
Sbjct: 932 AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985
Query: 66 SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122
E L + + KEK +Q H + + A ED + K +L++ + +LE + +
Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045
Query: 123 -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161
DLERAKR +IM +E+ +Q+L++ +++ F L+S++++++
Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 162 LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211
L +Q R+++ ++ E A + K EK R+ + +E +ER + A AT +
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
++++ N+ K LA +KQ+ E T EL Q+ +R EL E L Q+ET R
Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506
Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
EN L+ E+ + E Q +EG ++I LE K +++EQ +
Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545
Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168
L+ A SLE E + LNQ ++R A + E+D+ K N ++ES+Q
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 169 LKD-EARDLRQELAVQQKQE 187
D E R + +++K E
Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625
Score = 42.0 bits (97), Expect = 8e-04
Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%)
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
E+ T+KE+F+ ++D+LA+++A + +L++ + L + +DL+ +A
Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902
Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
L D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Score = 36.2 bits (82), Expect = 0.042
Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%)
Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60
S EEE+ DL QR Q E EF E EA L +QL QQIE
Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321
Query: 61 NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107
R L E N L R + + ++E++E + +E R +S ++AQ +
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379
Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
KY + Q ++LE AK+ L+ E+ + + A LE ++ Q
Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425
Query: 168 RLKDEARDL 176
RL++E DL
Sbjct: 1426 RLQNEVEDL 1434
Score = 35.0 bits (79), Expect = 0.094
Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82
Q + + + LRE E +E +AEL+ L + T + E + ++ ELE K+K
Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399
Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135
+ + A+ A + K +LQ + +L E+ N L++ +R L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459
Query: 136 EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176
+++Q+ + +NA+ ES LD+ E L + L+ E DL
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518
Query: 177 RQELAVQQKQEKPRTPMPSSVEAERTD 203
+++A K+ + VE E+ +
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 19/186 (10%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA + ++ D ++E L+ +K+K E +
Sbjct: 1167 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1222
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELE-QAND---DLERAKRATIMSLEDFEQR 141
SE ++ + ++ Q K L+K R LE QAN+ LE A+R SL DF +
Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR----SLNDFTTQ 1278
Query: 142 LNQAIERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSV 197
+ N L +L+EKE L+ + R K + DL+++L +++ K + + ++
Sbjct: 1279 RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL---EEEGKAKNALAHAL 1335
Query: 198 EAERTD 203
++ R D
Sbjct: 1336 QSARHD 1341
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%)
Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
A+ KQR N + L E+++ E ++ELE+ ++ + + +L N LE + E
Sbjct: 1443 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1499
Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
F+ ++ +IS L + L + +L+K ++LE +L+ A SLE E +
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGK 1559
Query: 142 LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185
+ +A +E N A +E +L EK+ +E +R L E R + L V++K
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK 1619
Query: 186 QE 187
E
Sbjct: 1620 ME 1621
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/180 (23%), Positives = 74/180 (41%), Gaps = 17/180 (9%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+++ EE+ + + + L+T L ETR+R+ E R++ ++E + E+Q
Sbjct: 1575 ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA-ETRSRN---EVLRVKKKMEGDLNEMEIQ 1630
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL-------ERAKRATIMSLEDF 138
S R + + + +++ Q + + +ANDDL ER LE+
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1690
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
+ Q E EL E E VQ L + L + ++K E T + S VE
Sbjct: 1691 RAVVEQTERSRKLAEQELIETS---ERVQLLHSQNTSLINQ---KKKMESDLTQLQSEVE 1744
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%)
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
E+ T+KE+F +++ L +++A + +L++ + L Q +DL+ +A
Sbjct: 850 EMATMKEEF-----------GRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898
Query: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180
+L D E+R +Q I+ LE+++ E LE + +L+DE +L++++
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Score = 38.5 bits (88), Expect = 0.009
Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 36/196 (18%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSE 67
EE++ N + +Q+ ++ + L + ++ + E +LE L+ + DL E
Sbjct: 1015 EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDL--E 1072
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE----LEQANDD 123
N++L++E + K++F++ +Q S +ED+ + + QLQK ++E +E+ ++
Sbjct: 1073 NDKLQLEEKLKKKEFDIN-----QQNSKIEDE----QVLALQLQKKLKENQARIEELEEE 1123
Query: 124 L--ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLES 165
L ER RA + LE+ +RL +A IE N E+E + + +L E+
Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183
Query: 166 VQRLKDEARDLRQELA 181
+ + A LR++ A
Sbjct: 1184 TLQHEATAAALRKKHA 1199
Score = 38.1 bits (87), Expect = 0.011
Identities = 51/231 (22%), Positives = 100/231 (43%), Gaps = 35/231 (15%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL-REFQE----------GSREYEAE 49
+ED + + EEA + T + + + EL R+ +E G Y +
Sbjct: 1254 LEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313
Query: 50 LETQLQQIETRNRD---LLSENNRLRMELETIKEKFEVQ---HSEGYRQISALEDDLAQT 103
+E +Q+E + L R + + ++E++E + +E R +S ++AQ
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
Query: 104 KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESE----LDEK 159
+ KY + Q ++LE AK+ L+D E+ + + + LE +E
Sbjct: 1374 RT------KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427
Query: 160 ENLLESVQR-------LKDEARDLRQELAV-QQKQEKPRTPMPSSVEAERT 202
E+L+ V+R L + R+ + LA +QK E+ ++ + SS + R+
Sbjct: 1428 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1478
Score = 38.1 bits (87), Expect = 0.011
Identities = 43/210 (20%), Positives = 93/210 (44%), Gaps = 38/210 (18%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQ---EGSREYEAELETQLQQIETRNRDLLSEN 68
E + ++ +A +++ ++ Q L++ Q + + +L+ + +E RN L +E
Sbjct: 1628 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 1687
Query: 69 NRLR--------------MELETIKEKFEVQHSEG---YRQISALEDDLAQTKAIKDQLQ 111
LR EL E+ ++ HS+ Q +E DL Q ++ +++
Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ---LQSEVE 1744
Query: 112 KYIRELEQANDDLERAKRATIMSLEDFE---------QRLNQAIERNAF-LESELDEKEN 161
+ ++E A + ++A M E+ + +R+ + +E+ L+ LDE E
Sbjct: 1745 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
Query: 162 LL-----ESVQRLKDEARDLRQELAVQQKQ 186
+ + +Q+L+ R+L EL +QK+
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKR 1834
Score = 37.7 bits (86), Expect = 0.015
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 17/141 (12%)
Query: 38 EFQEGSREYEAELETQLQQIETRNRD----------LLSENNRLRMELETIKEKFEVQHS 87
EF + E E +L + +++E R+ L R R E+ +K+K E +
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147
E Q+S A+ + LQ +++ + DD RA +D ++ +
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN-------DDLKENIAIVER 1678
Query: 148 RNAFLESELDEKENLLESVQR 168
RN L++EL+E ++E +R
Sbjct: 1679 RNNLLQAELEELRAVVEQTER 1699
Score = 37.0 bits (84), Expect = 0.025
Identities = 35/177 (19%), Positives = 80/177 (45%), Gaps = 15/177 (8%)
Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL----ETQLQQIETRNRDLLSEN 68
EE +D + ++ +N ++ +++ Q E E + QLQ++E R R+L E
Sbjct: 1769 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGE- 1827
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+E E + +++E + + E + + ++ +K + L+ D L+
Sbjct: 1828 ----LEAE------QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185
+A E+ E++ N + + ++ ELDE E + + ++ R +++ +QK
Sbjct: 1878 KAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQK 1934
Score = 34.3 bits (77), Expect = 0.16
Identities = 43/172 (25%), Positives = 78/172 (45%), Gaps = 14/172 (8%)
Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNR 70
EE K+ Q A + + LRE E E +AEL+ L + + + E +
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 71 LRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
++ ELE K+K + + + A+ + + K +LQ E+E D+ER+
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS- 1437
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
A +L+ ++ ++ + A + + +E ++ LES Q+ EAR L EL
Sbjct: 1438 NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1483
Score = 33.9 bits (76), Expect = 0.21
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 43 SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102
S E E E+ T ++ R ++ L ++ R ELE + ++ Q+ A +D+L
Sbjct: 844 SAETEKEMATMKEEFG-RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902
Query: 103 TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENL 162
+ DQL K +LE +++ +RL E NA L + +K L
Sbjct: 903 AEERCDQLIKNKIQLE--------------AKVKEMNERLEDEEEMNAELTA---KKRKL 945
Query: 163 LESVQRLKDEARDLRQELAVQQKQE 187
+ LK + DL LA +K++
Sbjct: 946 EDECSELKKDIDDLELTLAKVEKEK 970
Score = 30.8 bits (68), Expect = 1.8
Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 15/172 (8%)
Query: 31 NTQEELREFQEGSREYEAELET---QLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
N ++ R ++ + EY +LE L T+ L +EN L +LE KE Q +
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE-KEALISQLT 1304
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147
G L+ T+ ++D L++ + E +A + L A ++ + ++ + E
Sbjct: 1305 RG---------KLSYTQQMED-LKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354
Query: 148 RNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
A L+ L K N + R K E +++ +++ ++K + + EA
Sbjct: 1355 AKAELQRVL-SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA 1405
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 53.5 bits (127), Expect = 3e-07
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 24/189 (12%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
++++ N+ K L+ +KQ+ E TQ EL Q+ SR EL E L Q+ET R
Sbjct: 1446 DKKQRNFDKVLS-EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR- 1503
Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
EN L+ E+ + E Q +EG +QI LE Q + K ++Q LE+A
Sbjct: 1504 ---ENKNLQQEISDLTE----QIAEGGKQIHELEKIKKQVEQEKCEIQ---AALEEAEAS 1553
Query: 124 LERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KEN---LLESVQRLKD-EARDLRQ 178
LE + + + Q ++ + A + E+D+ K N ++E++Q D E R
Sbjct: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRND 1613
Query: 179 ELAVQQKQE 187
L V++K E
Sbjct: 1614 ALRVKKKME 1622
Score = 49.3 bits (116), Expect = 5e-06
Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 19/186 (10%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA + + ++ D ++E L+ +K+K E +
Sbjct: 1168 KKREAEFQKLRRDLEEATLQHEA----MVAALRKKHADSMAELGEQIDNLQRVKQKLEKE 1223
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
SE + L + K L+K R LE +L+ + E+ ++ +N
Sbjct: 1224 KSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE-------EEQQRLINDL 1276
Query: 146 IERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSV 197
+ A L++E LDEK+ L+ + R K + +EL Q ++E K + + ++
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336
Query: 198 EAERTD 203
++ R D
Sbjct: 1337 QSSRHD 1342
Score = 45.1 bits (105), Expect = 9e-05
Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 37/203 (18%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
+A+ E+ + EGS E E +L L++ + + L M++E K++ + +
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI--------M 133
+ +IS L + +A++ QLQK I+EL+ ++L ERA RA
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144
Query: 134 SLEDFEQRLNQA-------IERNAFLESELDEKENLLES--------VQRLKDEARDLRQ 178
LE+ +RL +A +E N E+E + LE V L+ + D
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
Query: 179 ELA--------VQQKQEKPRTPM 193
EL V+QK EK ++ +
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSEL 1227
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%)
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
E+ T+KE+F+ +D+LA+++A + +L++ + L + +DL+ ++
Sbjct: 851 EMATMKEEFQ-----------KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAD 899
Query: 134 SLEDFEQRLNQAIERNAFLESELDE-----------KENLLESVQRLKDEARDLRQEL 180
SL D E+R Q I+ LE+++ E L ++L+DE +L++++
Sbjct: 900 SLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 21/146 (14%)
Query: 35 ELREFQEGSREYEAELETQLQQIETRNRDLLSEN-NRLRMELETIKEKFEVQH---SEGY 90
+L ++ S + EL+ QL++ ET+ ++ L+ R + + ++E++E + +E
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEE-ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQ 1361
Query: 91 RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150
R +S ++AQ + KY + Q ++LE AK+ L++ E+ + + A
Sbjct: 1362 RALSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA 1415
Query: 151 FLESELDEKENLLESVQRLKDEARDL 176
LE ++ QRL++E DL
Sbjct: 1416 SLE----------KTKQRLQNEVEDL 1431
Score = 38.1 bits (87), Expect = 0.011
Identities = 41/196 (20%), Positives = 79/196 (40%), Gaps = 25/196 (12%)
Query: 33 QEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQ 92
+E+ E QEG E + L ++ ++ + ELE K+K + E
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEH 1406
Query: 93 ISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSLEDFEQRL--- 142
+ A+ A + K +LQ + +L E++N L++ +R L +++Q+
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466
Query: 143 ----------NQAIERNAF-----LESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187
++++ F E LD+ E L + L+ E DL +++A KQ
Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526
Query: 188 KPRTPMPSSVEAERTD 203
+ VE E+ +
Sbjct: 1527 HELEKIKKQVEQEKCE 1542
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/182 (22%), Positives = 84/182 (46%), Gaps = 11/182 (6%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA + ++ D ++E L+ +K+K E +
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1220
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
SE ++ + ++ Q K L+K R LE ++ T S+ D + +
Sbjct: 1221 KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKL 1280
Query: 146 IERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSVEAER 201
N L +LDEKE L+ + R K + DL+++L +++ K + + ++++ R
Sbjct: 1281 QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL---EEEVKAKNALAHALQSAR 1337
Query: 202 TD 203
D
Sbjct: 1338 HD 1339
Score = 48.5 bits (114), Expect = 8e-06
Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%)
Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
A+ KQR N + L E+++ E ++ELE+ ++ + + +L N LE + E
Sbjct: 1441 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1497
Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
F+ ++ +IS L + L + +L+K ++LE +L+ A SLE E +
Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557
Query: 142 LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185
+ +A +E N A +E +L EK+ +E +R L E R + L V++K
Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617
Query: 186 QE 187
E
Sbjct: 1618 ME 1619
Score = 45.4 bits (106), Expect = 7e-05
Identities = 57/226 (25%), Positives = 103/226 (45%), Gaps = 42/226 (18%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIET---R 60
++++ N+ K LA +KQ+ E +Q EL Q+ +R EL E L+ +ET
Sbjct: 1443 DKKQRNFDKILA-EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501
Query: 61 NRDLLSENNRL------------------------RMELETIKEKFE--VQHSEGYRQIS 94
N++L E + L +MEL++ E+ E ++H EG +I
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG--KIL 1559
Query: 95 ALEDDLAQTKA-IKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
+ + Q KA I+ +L + E+EQA + R + SL+ + N+A+ +E
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619
Query: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
+L+E E L R+ EA+ +Q ++Q + + + +V A
Sbjct: 1620 GDLNEMEIQLSHANRMAAEAQ--KQVKSLQSLLKDTQIQLDDAVRA 1663
Score = 42.4 bits (98), Expect = 6e-04
Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
+EE++ N + +Q+ ++ EGS E E ++ L++ + + L
Sbjct: 1012 AEEDKVNTLTKAKVKLEQQVDDL--------EGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
M+LE K++ + + + +++AL + +A+ QLQK ++EL+ ++L
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
ER RA + LE+ +RL +A IE N E+E + + +L E+
Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183
Query: 168 RLKDEARDLRQELA 181
+ + A LR++ A
Sbjct: 1184 QHEATAAALRKKHA 1197
Score = 39.3 bits (90), Expect = 0.005
Identities = 38/169 (22%), Positives = 80/169 (47%), Gaps = 24/169 (14%)
Query: 23 MTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
M YK+ E ++ L Q R + ++ + + LL R + E+ ++KE+F
Sbjct: 799 MEYKKLLER-RDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREK-EMASMKEEF 856
Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
+ L++ L +++A + +L++ + L Q +DL+ +A +L D E+R
Sbjct: 857 -----------TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 143 NQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180
+Q I+ LE+++ E LE + +L+DE +L++++
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Score = 39.3 bits (90), Expect = 0.005
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 11/161 (6%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
EE EA+ + + + E Q E R+ E E E L+ +++ L +E
Sbjct: 1545 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAE 1604
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
R R E +K+K E +E Q+S A+ + LQ +++ + DD RA
Sbjct: 1605 T-RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168
+D ++ + RN L++EL+E ++E +R
Sbjct: 1664 N-------DDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
Score = 38.1 bits (87), Expect = 0.011
Identities = 37/158 (23%), Positives = 76/158 (48%), Gaps = 16/158 (10%)
Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
EELR E + E +L + R + L S+N L + K+K + S+ ++
Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ----KKKMDADLSQLQTEV 1741
Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
E+ + + + +++ +K I + ++L++ ++ T LE ++ + Q I+ L+
Sbjct: 1742 ---EEAVQECRNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKKNMEQTIKD---LQ 1794
Query: 154 SELDEKENLL-----ESVQRLKDEARDLRQELAVQQKQ 186
LDE E + + +Q+L+ R+L EL +QK+
Sbjct: 1795 HRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKR 1832
Score = 35.4 bits (80), Expect = 0.072
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 15/173 (8%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENN 69
EEE LA Q A + + LRE E E +AEL+ L + + + E +
Sbjct: 1320 EEEVKAKNALAHAL-QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378
Query: 70 RLRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
++ ELE K+K + E + A+ + + K +LQ E+E D+ER+
Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS 1435
Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
A +L+ ++ ++ + A + + +E ++ LES Q+ EAR L EL
Sbjct: 1436 -NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1481
Score = 33.1 bits (74), Expect = 0.36
Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 35/191 (18%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+++ EE+ + + L+T L ETR+R+ E R++ ++E + E+Q
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA-ETRSRN---EALRVKKKMEGDLNEMEIQ 1628
Query: 86 HS-------EGYRQISALE-----------------DDLAQTKAIKDQ----LQKYIREL 117
S E +Q+ +L+ DDL + AI ++ LQ + EL
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1688
Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
+ ER+++ L + +R+ +N L +++K+ + + +L+ E +
Sbjct: 1689 RAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL---INQKKKMDADLSQLQTEVEEAV 1745
Query: 178 QELAVQQKQEK 188
QE +++ K
Sbjct: 1746 QECRNAEEKAK 1756
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.1 bits (126), Expect = 3e-07
Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%)
Query: 12 EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62
E+E W+ ++Q + +E++RE +E RE E ++ Q ++I ++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 63 DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119
+ + + + E I+E+ E + + +RQ + + + + ++++ ++ IRELE+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178
D E R +++ E+++ + E+ E ++ E+E ++ LK E + Q
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 179 ELAVQQKQEK 188
E + +++EK
Sbjct: 502 EEKMWRQEEK 511
Score = 48.5 bits (114), Expect = 8e-06
Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66
+EE+ ++ +++ +E++RE E +E E E+ Q ++I E R +
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
+ ++R + E I+E Q E +RQ E+ + + + + ++ +RE+E+ + E
Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185
+ ++ E+++ + E+ E L ++E + E +++ + E + QE +Q++
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 186 QEK 188
+EK
Sbjct: 523 EEK 525
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
M + + +EEE ++ ++ ++ +E+LRE +E +E E +++ Q ++I+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 61 NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115
+ + + + + +K EK Q + +RQ + E+ + + + + ++ +R
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158
E E E + + L++ E+RL + ++ L +++
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594
Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195
K +S+Q+ +D R L+Q +A Q+ + +PS
Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67
++++E W+ +Q + ++EL RE +E E ++ Q ++I + + +
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
++R + E I+E Q + +RQ + + Q + I++Q ++ R+ E+ + E+
Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183
+ + + ++++ + E E ++ E E ++ + ++L++ +++E
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 184 QKQEKPRTPMPSSVEAERTDT 204
Q+QE+ ++ + T
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485
Score = 32.0 bits (71), Expect = 0.80
Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 31/195 (15%)
Query: 1 MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58
M + TF W L +T ++R EN+ EE F R + T ++++
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195
Query: 59 TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
T+ RD S E R + E +KEK + L++ L ++ K ++Q +++L
Sbjct: 196 TKERDAPSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244
Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173
++ LERA+ E RL + ++ +A L+++++E E NLL Q E
Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297
Query: 174 RDLRQELAVQQKQEK 188
+ RQE +Q+++EK
Sbjct: 298 KMWRQEEKIQEQEEK 312
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 53.1 bits (126), Expect = 3e-07
Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%)
Query: 12 EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62
E+E W+ ++Q + +E++RE +E RE E ++ Q ++I ++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
Query: 63 DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119
+ + + + E I+E+ E + + +RQ + + + + ++++ ++ IRELE+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178
D E R +++ E+++ + E+ E ++ E+E ++ LK E + Q
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 179 ELAVQQKQEK 188
E + +++EK
Sbjct: 502 EEKMWRQEEK 511
Score = 48.5 bits (114), Expect = 8e-06
Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66
+EE+ ++ +++ +E++RE E +E E E+ Q ++I E R +
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
+ ++R + E I+E Q E +RQ E+ + + + + ++ +RE+E+ + E
Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185
+ ++ E+++ + E+ E L ++E + E +++ + E + QE +Q++
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 186 QEK 188
+EK
Sbjct: 523 EEK 525
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
M + + +EEE ++ ++ ++ +E+LRE +E +E E +++ Q ++I+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 61 NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115
+ + + + + +K EK Q + +RQ + E+ + + + + ++ +R
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158
E E E + + L++ E+RL + ++ L +++
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594
Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195
K +S+Q+ +D R L+Q +A Q+ + +PS
Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67
++++E W+ +Q + ++EL RE +E E ++ Q ++I + + +
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
++R + E I+E Q + +RQ + + Q + I++Q ++ R+ E+ + E+
Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183
+ + + ++++ + E E ++ E E ++ + ++L++ +++E
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 184 QKQEKPRTPMPSSVEAERTDT 204
Q+QE+ ++ + T
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485
Score = 34.7 bits (78), Expect = 0.12
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 31/195 (15%)
Query: 1 MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58
M + TF W L +T ++R EN+ EE F R + T ++++
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195
Query: 59 TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
T+ RD LS E R + E +KEK + L++ L ++ K ++Q +++L
Sbjct: 196 TKERDALSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244
Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173
++ LERA+ E RL + ++ +A L+++++E E NLL Q E
Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297
Query: 174 RDLRQELAVQQKQEK 188
+ RQE +Q+++EK
Sbjct: 298 KMWRQEEKIQEQEEK 312
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 8/184 (4%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL------ 64
+EEE + +++ +E LRE + RE E ++ Q +++ + ++L
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 65 LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124
L E +LR + E ++E+ E + + E Q + + +Q +K +RE EQ D
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMRDQ 357
Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQ 184
E L + E+R+ + E+ E ++ E+E + E +++++E +R++ Q
Sbjct: 358 EERMWEQDERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Query: 185 KQEK 188
KQE+
Sbjct: 417 KQEE 420
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 2/181 (1%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENNR 70
E+E + ++ M ++R ++++RE +E RE E +++ Q + + E ++ +
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAKR 129
+ E +EK + Q + + Q + D K Q+ +RE E + E R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 130 ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKP 189
+ D E+R+ + ER E + E++ + + +++++E + QE ++EK
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 190 R 190
R
Sbjct: 557 R 557
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/192 (21%), Positives = 95/192 (49%), Gaps = 15/192 (7%)
Query: 26 KQRAENTQEELREFQEGSREYEA--ELETQLQQ---IETRNRDLLSENNRLRMELETIKE 80
++R E LRE +E RE E E E ++Q+ I R + + E +R + E +++
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 81 K----FEVQHSEGYRQ-ISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM-- 133
+ +E + E +Q + ++ L + + +++Q +K + E+ D E + M
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 134 --SLEDFEQRLNQAIERNAFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
+ + E ++ + E+ E ++ D++E + E +RL+++ +R++ + Q++EK R
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 191 TPMPSSVEAERT 202
+ + ++T
Sbjct: 538 EEKKTQEQEKKT 549
Score = 38.9 bits (89), Expect = 0.007
Identities = 34/182 (18%), Positives = 86/182 (47%), Gaps = 8/182 (4%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+E+E W+ Q QE+ QE RE E ++ Q +++ + + + + R
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ + E ++EK E + +++ E+ + + K ++Q +K + E+ ++ +R
Sbjct: 509 MWEQDERLREKEERMREQ--KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLL----ESVQRLKDEARDLRQELAVQQKQ 186
M E E+ + + E+ E ++ E+E + E +Q +++ + +++ Q+++
Sbjct: 567 KKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Query: 187 EK 188
+K
Sbjct: 625 DK 626
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/215 (16%), Positives = 99/215 (46%), Gaps = 20/215 (9%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
M + KT E+E+ + ++ M ++R ++++RE +E RE E +++ Q +++ +
Sbjct: 536 MREEKKT--QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 61 NRDLLSENNRLRMELETI------------KEKFEVQHSEGYRQISALEDD----LAQTK 104
+ + +++ + E + ++K + Q + Q +++ Q +
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 105 AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESEL-DEKENLL 163
+++Q +K +RE E+ E R ++ E+++ + E+ E ++ ++E +
Sbjct: 654 KMREQEEK-MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 164 ESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
+++ + +E ++ ++EK + +P E
Sbjct: 713 GQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 38.1 bits (87), Expect = 0.011
Identities = 40/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)
Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72
EE +D R T EEL++ AEL+ +L+ E SE + ++
Sbjct: 162 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLRLAE-------SEKSEIQ 207
Query: 73 MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+ ++ +K K E + Q + L++++ + + + +K IR+ E+ E R
Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190
+ + E+++ + +R E EL E+E L ++L+++ ++ QE + +++EK R
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Score = 30.4 bits (67), Expect = 2.3
Identities = 39/191 (20%), Positives = 75/191 (39%), Gaps = 28/191 (14%)
Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELET 77
T K++ N EG E E + Q E R++ ++++ +R+ ELET
Sbjct: 47 TKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELET 106
Query: 78 I-------KEKFE-------------VQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
KFE + HS + L+ L+ + +YI EL
Sbjct: 107 ALYYSQDAARKFEDGNLGESKDLAGRLHHS--WHFAGELQRALSAVSTWHKKADRYIEEL 164
Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
+ D L ++ E+ +++ + E+ ESE E + ++ ++R + A+ L
Sbjct: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLL 224
Query: 178 QELAVQQKQEK 188
++ QE+
Sbjct: 225 PQVQTNTLQEE 235
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+QR EN + + Q ++ E + +L++++ + + L + + R +E +KE+ + Q
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598
Query: 86 HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140
+ + QI A E+ LA+ KA K K + E+E E A+R + E+ E+
Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658
Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
R L+ + +E++ L K A QE Q+++E+ R
Sbjct: 659 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702
Score = 42.7 bits (99), Expect = 5e-04
Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%)
Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
T K + E EE + + +++ E + Q+ E R L + R E +++K E
Sbjct: 610 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669
Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
+ E R+ A+ K + +Q ++ RE E+ + +R E Q
Sbjct: 670 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 721
Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194
Q R E EL E+E L E +QR +E + + +Q LA +Q QE+
Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240
+ A + D A S TP HR P P ++ L DDST
Sbjct: 782 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 832
Score = 38.9 bits (89), Expect = 0.007
Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
EEEE + + L +++ E QE LR+ E R E + E + ++ E R ++ + R
Sbjct: 654 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 708
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ E ++ E + ++ A + + KA++ Q ++ RELE+ E+ + A
Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768
Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
E+ E++ +A + L +D + S Q
Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 805
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
+QR EN + + Q ++ E + +L++++ + + L + + R +E +KE+ + Q
Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594
Query: 86 HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140
+ + QI A E+ LA+ KA K K + E+E E A+R + E+ E+
Sbjct: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654
Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
R L+ + +E++ L K A QE Q+++E+ R
Sbjct: 655 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
Score = 42.7 bits (99), Expect = 5e-04
Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%)
Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
T K + E EE + + +++ E + Q+ E R L + R E +++K E
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
+ E R+ A+ K + +Q ++ RE E+ + +R E Q
Sbjct: 666 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 717
Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194
Q R E EL E+E L E +QR +E + + +Q LA +Q QE+
Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240
+ A + D A S TP HR P P ++ L DDST
Sbjct: 778 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 828
Score = 38.9 bits (89), Expect = 0.007
Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
EEEE + + L +++ E QE LR+ E R E + E + ++ E R ++ + R
Sbjct: 650 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 704
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ E ++ E + ++ A + + KA++ Q ++ RELE+ E+ + A
Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764
Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
E+ E++ +A + L +D + S Q
Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 801
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
+EE + +Q+ EEL E E + +A L+ Q +E N DL E L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+ E+E K+K E Q E + S E A+ + D++ K E+E L A+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 189 PRTPMPSSVEAERTDT 204
S++ + +D+
Sbjct: 1361 NLERHISTLNIQLSDS 1376
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+EEE +D K+R + + EL+E ++ + E +Q++ +L +E
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
+R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
A I LED + + N+ + LE + L E+E +++ +L
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028
Query: 170 KDEARDLRQELAVQQKQEK 188
K++ + EL V+ K+E+
Sbjct: 1029 KNKHESMISELEVRLKKEE 1047
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)
Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
+ + +K KF+ I+ALE +AQ +++Q+++ RE + A L +
Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848
Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
E GK ++ A+ L T + E T+++L R+ +E + +L+ +++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357
Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
+ R + LS++ + + + E E ++I L + A D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
L+K L+Q DDL +R + +LE +++ +Q A E+N E+E
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
EKE S+ R +EA + ++EL K K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ D + EEE+A L ++ + L++ +E SR+ ELE +++E
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
DL+ ED + ER A ++E +K +L E ++ LK E D
Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162
Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200
A QQ K+E+ T + +++ E
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)
Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
LA ++R + + FQ R Y A +Q + ++ N ++L
Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834
Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+K +V E ++ A ED+L +TK + + + ++ELEQ + L K
Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L+ + +A E L ++ E E +L ++ +E D Q+L ++K+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+E + K +E E+ KD E ++ L E + ELE +LQ E
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E
Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604
Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
+D ER +RA + L+D E + + AI+ +L + + ++ QR ++
Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
AR R E+ K+ + + S+EA+
Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)
Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
+G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347
Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
+D L E + LE +Q S+ +++ + + K + QK I L Q
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
A D LE+ K L+D L+ + + LE + + + LL + + +
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467
Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
D R + ++++ + + + E ERT+ ++A
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
AE + L ++ E E+E +L++ E R + L +E ++ ++ E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
++K +++ +I LED++ ++L K + LE+ DL E K +
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q
Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)
Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
+ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213
Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
+ R + L+ K+ E ++++ ++ L + + K +L+ ++EL+
Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
D ERA+ L D +L +E + +E + K L + V L + +D ++
Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201
L + +Q+ + +E ER
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345
Score = 36.6 bits (83), Expect = 0.032
Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)
Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
+ L +++ + L E + S +Y E + + + LS L LE
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
KE+ E + + + A +DL +K D + K + ELE++ LE LE+
Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
E L + LE + + E + +DE + ++ EL ++KQ
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
+E + D +QA ++ A + F+R L+D+
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Score = 36.2 bits (82), Expect = 0.042
Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
N +++RE + + + +L+++ + E + RDL E L+ ELE + Q
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226
Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
Q L + NA L EL + + K E +++L Q ++ + + A
Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276
Query: 200 ERTDTAVQATGSVPS 214
E D + V S
Sbjct: 1277 ELNDKVHKLQNEVES 1291
Score = 35.4 bits (80), Expect = 0.072
Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
+E+ K F E E +++ A Y + E T+ L++ + + + +L + L++
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
+ + LL+E + + +++ E + E + +L L + K++L++ +
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563
Query: 177 RQELAVQ 183
R E+ +Q
Sbjct: 1564 RLEVNMQ 1570
Score = 31.6 bits (70), Expect = 1.0
Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
+ E+ + A K +L++ + E+E LE+ E R Q
Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943
Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
ER + LD +E L E R K + + E +++ +++
Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
Score = 30.4 bits (67), Expect = 2.3
Identities = 18/77 (23%), Positives = 34/77 (44%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ED K +E+A K++ E +EE + R+ + EL+ + E
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917
Query: 61 NRDLLSENNRLRMELET 77
R++ + ++LR ET
Sbjct: 1918 GREVNALKSKLRRGNET 1934
Score = 28.5 bits (62), Expect = 8.8
Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E +
Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 87 SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
+ + LE+ +++ I +K REL++A + E R + +L+ +R N+
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1933
Query: 147 ERNAFLESELDEKENLLESVQRLKDE 172
+F+ S ++E+ ++E
Sbjct: 1934 --TSFVPSRRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
+EE + +Q+ EEL E E + +A L+ Q +E N DL E L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+ E+E K+K E Q E + S E A+ + D++ K E+E L A+
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 189 PRTPMPSSVEAERTDT 204
S++ + +D+
Sbjct: 1368 NLERHISTLNIQLSDS 1383
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+EEE +D K+R + + EL+E ++ + E +Q++ +L +E
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
+R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
A I LED + + N+ + LE + L E+E +++ +L
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035
Query: 170 KDEARDLRQELAVQQKQEK 188
K++ + EL V+ K+E+
Sbjct: 1036 KNKHESMISELEVRLKKEE 1054
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)
Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
+ + +K KF+ I+ALE +AQ +++Q+++ RE + A L +
Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855
Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
E GK ++ A+ L T + E T+++L R+ +E + +L+ +++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364
Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
+ R + LS++ + + + E E ++I L + A D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
L+K L+Q DDL +R + +LE +++ +Q A E+N E+E
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
EKE S+ R +EA + ++EL K K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ D + EEE+A L ++ + L++ +E SR+ ELE +++E
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
DL+ ED + ER A ++E +K +L E ++ LK E D
Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169
Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200
A QQ K+E+ T + +++ E
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)
Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
LA ++R + + FQ R Y A +Q + ++ N ++L
Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841
Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+K +V E ++ A ED+L +TK + + + ++ELEQ + L K
Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L+ + +A E L ++ E E +L ++ +E D Q+L ++K+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+E + K +E E+ KD E ++ L E + ELE +LQ E
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E
Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611
Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
+D ER +RA + L+D E + + AI+ +L + + ++ QR ++
Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
AR R E+ K+ + + S+EA+
Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)
Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
+G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354
Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
+D L E + LE +Q S+ +++ + + K + QK I L Q
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
A D LE+ K L+D L+ + + LE + + + LL + + +
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474
Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
D R + ++++ + + + E ERT+ ++A
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
AE + L ++ E E+E +L++ E R + L +E ++ ++ E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
++K +++ +I LED++ ++L K + LE+ DL E K +
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q
Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)
Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
+ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220
Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
+ R + L+ K+ E ++++ ++ L + + K +L+ ++EL+
Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
D ERA+ L D +L +E + +E + K L + V L + +D ++
Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201
L + +Q+ + +E ER
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352
Score = 36.6 bits (83), Expect = 0.032
Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)
Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
+ L +++ + L E + S +Y E + + + LS L LE
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
KE+ E + + + A +DL +K D + K + ELE++ LE LE+
Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
E L + LE + + E + +DE + ++ EL ++KQ
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
+E + D +QA ++ A + F+R L+D+
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Score = 36.2 bits (82), Expect = 0.042
Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
N +++RE + + + +L+++ + E + RDL E L+ ELE + Q
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233
Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
Q L + NA L EL + + K E +++L Q ++ + + A
Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283
Query: 200 ERTDTAVQATGSVPS 214
E D + V S
Sbjct: 1284 ELNDKVHKLQNEVES 1298
Score = 35.4 bits (80), Expect = 0.072
Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
+E+ K F E E +++ A Y + E T+ L++ + + + +L + L++
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
+ + LL+E + + +++ E + E + +L L + K++L++ +
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570
Query: 177 RQELAVQ 183
R E+ +Q
Sbjct: 1571 RLEVNMQ 1577
Score = 31.6 bits (70), Expect = 1.0
Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
+ E+ + A K +L++ + E+E LE+ E R Q
Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950
Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
ER + LD +E L E R K + + E +++ +++
Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993
Score = 30.4 bits (67), Expect = 2.3
Identities = 18/77 (23%), Positives = 34/77 (44%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ED K +E+A K++ E +EE + R+ + EL+ + E
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924
Query: 61 NRDLLSENNRLRMELET 77
R++ + ++LR ET
Sbjct: 1925 GREVNALKSKLRRGNET 1941
Score = 28.5 bits (62), Expect = 8.8
Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E +
Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 87 SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
+ + LE+ +++ I +K REL++A + E R + +L+ +R N+
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1940
Query: 147 ERNAFLESELDEKENLLESVQRLKDE 172
+F+ S ++E+ ++E
Sbjct: 1941 --TSFVPSRRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
+EE + +Q+ EEL E E + +A L+ Q +E N DL E L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+ E+E K+K E Q E + S E A+ + D++ K E+E L A+
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 189 PRTPMPSSVEAERTDT 204
S++ + +D+
Sbjct: 1368 NLERHISTLNIQLSDS 1383
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+EEE +D K+R + + EL+E ++ + E +Q++ +L +E
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
+R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++
Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975
Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
A I LED + + N+ + LE + L E+E +++ +L
Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035
Query: 170 KDEARDLRQELAVQQKQEK 188
K++ + EL V+ K+E+
Sbjct: 1036 KNKHESMISELEVRLKKEE 1054
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)
Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
+ + +K KF+ I+ALE +AQ +++Q+++ RE + A L +
Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855
Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
E GK ++ A+ L T + E T+++L R+ +E + +L+ +++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364
Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
+ R + LS++ + + + E E ++I L + A D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
L+K L+Q DDL +R + +LE +++ +Q A E+N E+E
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
EKE S+ R +EA + ++EL K K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ D + EEE+A L ++ + L++ +E SR+ ELE +++E
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
DL+ ED + ER A ++E +K +L E ++ LK E D
Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169
Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200
A QQ K+E+ T + +++ E
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)
Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
LA ++R + + FQ R Y A +Q + ++ N ++L
Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841
Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+K +V E ++ A ED+L +TK + + + ++ELEQ + L K
Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L+ + +A E L ++ E E +L ++ +E D Q+L ++K+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+E + K +E E+ KD E ++ L E + ELE +LQ E
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E
Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611
Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
+D ER +RA + L+D E + + AI+ +L + + ++ QR ++
Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
AR R E+ K+ + + S+EA+
Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)
Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
+G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354
Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
+D L E + LE +Q S+ +++ + + K + QK I L Q
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
A D LE+ K L+D L+ + + LE + + + LL + + +
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474
Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
D R + ++++ + + + E ERT+ ++A
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
AE + L ++ E E+E +L++ E R + L +E ++ ++ E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
++K +++ +I LED++ ++L K + LE+ DL E K +
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q
Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)
Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
+ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220
Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
+ R + L+ K+ E ++++ ++ L + + K +L+ ++EL+
Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
D ERA+ L D +L +E + +E + K L + V L + +D ++
Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201
L + +Q+ + +E ER
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352
Score = 36.6 bits (83), Expect = 0.032
Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)
Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
+ L +++ + L E + S +Y E + + + LS L LE
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
KE+ E + + + A +DL +K D + K + ELE++ LE LE+
Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
E L + LE + + E + +DE + ++ EL ++KQ
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
+E + D +QA ++ A + F+R L+D+
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Score = 36.2 bits (82), Expect = 0.042
Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
N +++RE + + + +L+++ + E + RDL E L+ ELE + Q
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233
Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
Q L + NA L EL + + K E +++L Q ++ + + A
Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283
Query: 200 ERTDTAVQATGSVPS 214
E D + V S
Sbjct: 1284 ELNDKVHKLQNEVES 1298
Score = 35.4 bits (80), Expect = 0.072
Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
+E+ K F E E +++ A Y + E T+ L++ + + + +L + L++
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
+ + LL+E + + +++ E + E + +L L + K++L++ +
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570
Query: 177 RQELAVQ 183
R E+ +Q
Sbjct: 1571 RLEVNMQ 1577
Score = 31.6 bits (70), Expect = 1.0
Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E +
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
+ E+ + A K +L++ + E+E LE+ E R Q
Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950
Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
ER + LD +E L E R K + + E +++ +++
Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993
Score = 28.9 bits (63), Expect = 6.8
Identities = 16/72 (22%), Positives = 32/72 (44%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ED K +E+A K++ E +EE + R+ + EL+ + E
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924
Query: 61 NRDLLSENNRLR 72
R++ + ++LR
Sbjct: 1925 GREVNALKSKLR 1936
Score = 28.5 bits (62), Expect = 8.8
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E +
Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 87 S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ + RQ+ E++ + A + +LQ+ + E ++N+ + R A
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 52.8 bits (125), Expect = 4e-07
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)
Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
+EE + +Q+ EEL E E + +A L+ Q +E N DL E L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
+ E+E K+K E Q E + S E A+ + D++ K E+E L A+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300
Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 189 PRTPMPSSVEAERTDT 204
S++ + +D+
Sbjct: 1361 NLERHISTLNIQLSDS 1376
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
+EEE +D K+R + + EL+E ++ + E +Q++ +L +E
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908
Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
+R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++
Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968
Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
A I LED + + N+ + LE + L E+E +++ +L
Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028
Query: 170 KDEARDLRQELAVQQKQEK 188
K++ + EL V+ K+E+
Sbjct: 1029 KNKHESMISELEVRLKKEE 1047
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)
Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801
Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
+ + +K KF+ I+ALE +AQ +++Q+++ RE + A L +
Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848
Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
+ + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)
Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
E GK ++ A+ L T + E T+++L R+ +E + +L+ +++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357
Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
+ R + LS++ + + + E E ++I L + A D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
L+K L+Q DDL +R + +LE +++ +Q A E+N E+E
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
EKE S+ R +EA + ++EL K K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ D + EEE+A L ++ + L++ +E SR+ ELE +++E
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119
Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
DL+ ED + ER A ++E +K +L E ++ LK E D
Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162
Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200
A QQ K+E+ T + +++ E
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)
Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
LA ++R + + FQ R Y A +Q + ++ N ++L
Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834
Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
+K +V E ++ A ED+L +TK + + + ++ELEQ + L K
Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892
Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L+ + +A E L ++ E E +L ++ +E D Q+L ++K+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+E + K +E E+ KD E ++ L E + ELE +LQ E
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559
Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E
Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604
Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
+D ER +RA + L+D E + + AI+ +L + + ++ QR ++
Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
AR R E+ K+ + + S+EA+
Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688
Score = 42.0 bits (97), Expect = 8e-04
Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)
Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
+G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347
Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
+D L E + LE +Q S+ +++ + + K + QK I L Q
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
A D LE+ K L+D L+ + + LE + + + LL + + +
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467
Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
D R + ++++ + + + E ERT+ ++A
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)
Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
AE + L ++ E E+E +L++ E R + L +E ++ ++ E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
++K +++ +I LED++ ++L K + LE+ DL E K +
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q
Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)
Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
+ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213
Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
+ R + L+ K+ E ++++ ++ L + + K +L+ ++EL+
Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266
Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
D ERA+ L D +L +E + +E + K L + V L + +D ++
Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201
L + +Q+ + +E ER
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345
Score = 36.6 bits (83), Expect = 0.032
Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)
Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
+ L +++ + L E + S +Y E + + + LS L LE
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498
Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
KE+ E + + + A +DL +K D + K + ELE++ LE LE+
Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
E L + LE + + E + +DE + ++ EL ++KQ
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
+E + D +QA ++ A + F+R L+D+
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Score = 36.2 bits (82), Expect = 0.042
Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
N +++RE + + + +L+++ + E + RDL E L+ ELE + Q
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226
Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
Q L + NA L EL + + K E +++L Q ++ + + A
Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276
Query: 200 ERTDTAVQATGSVPS 214
E D + V S
Sbjct: 1277 ELNDKVHKLQNEVES 1291
Score = 35.4 bits (80), Expect = 0.072
Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
+E+ K F E E +++ A Y + E T+ L++ + + + +L + L++
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
+ + LL+E + + +++ E + E + +L L + K++L++ +
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563
Query: 177 RQELAVQ 183
R E+ +Q
Sbjct: 1564 RLEVNMQ 1570
Score = 31.6 bits (70), Expect = 1.0
Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)
Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E +
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903
Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
+ E+ + A K +L++ + E+E LE+ E R Q
Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943
Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
ER + LD +E L E R K + + E +++ +++
Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
Score = 28.9 bits (63), Expect = 6.8
Identities = 16/72 (22%), Positives = 32/72 (44%)
Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
+ED K +E+A K++ E +EE + R+ + EL+ + E
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917
Query: 61 NRDLLSENNRLR 72
R++ + ++LR
Sbjct: 1918 GREVNALKSKLR 1929
Score = 28.5 bits (62), Expect = 8.8
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E +
Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 87 S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
+ + RQ+ E++ + A + +LQ+ + E ++N+ + R A
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 52.8 bits (125), Expect = 4e-07
Identities = 49/187 (26%), Positives = 88/187 (47%), Gaps = 21/187 (11%)
Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E +
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL-NQ 144
SE +I L ++ K L+K R LE D L K + E+ +QRL N
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALE---DQLSEIK-----TKEEEQQRLIND 1276
Query: 145 AIERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSS 196
+ A L++E LDEK+ L+ + R K +EL Q ++E K ++ + +
Sbjct: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
Query: 197 VEAERTD 203
+++ R D
Sbjct: 1337 LQSSRHD 1343
Score = 48.9 bits (115), Expect = 6e-06
Identities = 56/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)
Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
+EE++ N + +Q+ ++ EGS E E ++ L++ + + L
Sbjct: 1016 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067
Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
M++E K++ + + + ++S L+ + +A+ QLQK I+EL+ ++L
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
ERA RA LE+ +RL +A IE N E+E + + +L E+
Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1187
Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
+ + A LR++ A V+QK EK ++ M ++ A +T +A G
Sbjct: 1188 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG 1247
Query: 211 SV 212
++
Sbjct: 1248 NL 1249
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/200 (28%), Positives = 90/200 (45%), Gaps = 46/200 (23%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
++++ N+ K LA +KQ+ E T EL Q+ SR EL E L Q+ET R
Sbjct: 1447 DKKQRNFDKILA-EWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR- 1504
Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
EN L+ E+ + E Q +EG ++I LE K +++EQ +
Sbjct: 1505 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKSE 1543
Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDEKE----NLLESVQR 168
L+ A SLE E + LNQ ++R A + E+D+ + ++ES+Q
Sbjct: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603
Query: 169 LKD-EARDLRQELAVQQKQE 187
D E R + +++K E
Sbjct: 1604 TLDAEIRSRNDAIRLKKKME 1623
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 22/118 (18%)
Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
E+ +KE+FE +++LA+T+A + +L++ + L Q +DL+ +A
Sbjct: 852 EMANMKEEFE-----------KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
SL D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958
Score = 37.0 bits (84), Expect = 0.025
Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 22/158 (13%)
Query: 25 YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL---RMELETIKEK 81
Y ++ + + + G + + ++E +Q+E + + + L R + + ++E+
Sbjct: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350
Query: 82 FEVQH---SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
+E + +E R +S ++AQ + KY + Q ++LE AK+ L+D
Sbjct: 1351 YEEEQEAKAELQRAMSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQDA 1404
Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
E+ + + A LE ++ QRL++E DL
Sbjct: 1405 EEHVEAVNAKCASLE----------KTKQRLQNEVEDL 1432
Score = 32.0 bits (71), Expect = 0.80
Identities = 46/215 (21%), Positives = 87/215 (40%), Gaps = 40/215 (18%)
Query: 11 EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIE----TRNRD 63
EE EA+ + + + E Q E R+ E E + ++ +E T + +
Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608
Query: 64 LLSENN--RLRMELETIKEKFEVQHS----------EGYRQISA--------LEDDLAQT 103
+ S N+ RL+ ++E + E+Q + YR A L+D L
Sbjct: 1609 IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQ 1668
Query: 104 KAIKDQ----------LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
+ +K+Q LQ I EL + ER+++ L D +R+ +N L
Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL- 1727
Query: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
++ K+ L + +++ E D+ QE +++ K
Sbjct: 1728 --INTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,627,515
Number of Sequences: 37866
Number of extensions: 624546
Number of successful extensions: 8636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 887
Number of HSP's that attempted gapping in prelim test: 4213
Number of HSP's gapped (non-prelim): 3822
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.