Guide to the Human Genome
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Search of human proteins with 8922328

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922328 RNA binding motif protein 22 [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922328 RNA binding motif protein 22 [Homo sapiens]                891   0.0  
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    68   2e-11
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    68   2e-11
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    68   2e-11
gi|62460633 RNA-binding motif protein 16 [Homo sapiens]                66   5e-11
gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]          64   2e-10
gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]          64   2e-10
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                55   1e-07
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 55   2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    54   3e-07
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     52   8e-07
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]                     52   8e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    52   1e-06
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    52   1e-06
gi|153792074 proline rich 12 [Homo sapiens]                            52   1e-06
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]           52   1e-06
gi|206597502 NESH protein isoform 2 [Homo sapiens]                     52   1e-06
gi|7705981 NESH protein isoform 1 [Homo sapiens]                       52   1e-06
gi|11386183 WAS protein family, member 2 [Homo sapiens]                51   2e-06
gi|4507127 small nuclear ribonucleoprotein polypeptide C [Homo s...    51   2e-06
gi|56549694 enabled homolog isoform a [Homo sapiens]                   50   5e-06
gi|39930375 enabled homolog isoform b [Homo sapiens]                   50   5e-06
gi|18959210 WIRE protein [Homo sapiens]                                50   5e-06
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap...    50   5e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     49   7e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     49   7e-06
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap...    49   9e-06
gi|33356148 formin-like 1 [Homo sapiens]                               49   1e-05
gi|157168329 formin 1 [Homo sapiens]                                   48   1e-05
gi|160707881 formin 2 [Homo sapiens]                                   48   1e-05

>gi|8922328 RNA binding motif protein 22 [Homo sapiens]
          Length = 420

 Score =  891 bits (2303), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPG 60
           MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPG
Sbjct: 1   MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPG 60

Query: 61  VRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQN 120
           VRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQN
Sbjct: 61  VRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQN 120

Query: 121 MEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECP 180
           MEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECP
Sbjct: 121 MEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECP 180

Query: 181 YRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLG 240
           YRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLG
Sbjct: 181 YRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLG 240

Query: 241 DTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNV 300
           DTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNV
Sbjct: 241 DTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNV 300

Query: 301 KWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAV 360
           KWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAV
Sbjct: 301 KWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAV 360

Query: 361 VNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP 420
           VNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
Sbjct: 361 VNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP 420


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 70/251 (27%), Positives = 100/251 (39%), Gaps = 67/251 (26%)

Query: 215 KRASTMPRLDPPEDKTI-TTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQ 273
           +R   +P++ P       TTL+VG L    T+ D+ +   +FG I +I ++  + CA+I 
Sbjct: 490 RRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIV 549

Query: 274 FATRQAAEVAAEK-SFNKLIVNGRRLNVKWGRSQAARGKEKE------------------ 314
              RQ A  A +K S     VN + + + W  ++  +   K+                  
Sbjct: 550 MVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKP 609

Query: 315 -------KDGTTDS--------GI-----------------KLEPVPGLPGALP---PPP 339
                  + G  DS        GI                   EPV  +P  LP   PP 
Sbjct: 610 EELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 669

Query: 340 AAEEEASANYFNLPP--SGPPAVVNIALPPPPGIAPP---PPPGFGPHMFHPMGPPPPFM 394
                 +     +PP   GPP V  +    PP   PP   PPPGFGP +  P  PPPPF+
Sbjct: 670 PVPAPITVPPPQVPPHQPGPPVVGAL---QPPAFTPPLGIPPPGFGPGV-PPPPPPPPFL 725

Query: 395 RAPG--PIHYP 403
           R PG  P+H P
Sbjct: 726 R-PGFNPMHLP 735



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 41/143 (28%), Positives = 49/143 (34%), Gaps = 33/143 (23%)

Query: 308 ARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVN----- 362
           ARG  +  D     G  + P    P  LP PP  +  +      + P GP   +      
Sbjct: 770 ARGNAESGDSVKMYGSAVPPAA--PTNLPTPPVTQPVSLLGTQGVAP-GPVIGLQAPSTG 826

Query: 363 --------IALPPPPGIAPP--------PPPGFGPHMFH---PMG------PPPPFMRAP 397
                   I L  PPG+ PP        PP    PHM H   P G      PPP  M+ P
Sbjct: 827 LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP 886

Query: 398 GPIHYPSQDPQRMGAHAGKHSSP 420
            P H P   P  M    G    P
Sbjct: 887 FPPHGPFVRPGGMPGLGGPGPGP 909


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 70/251 (27%), Positives = 100/251 (39%), Gaps = 67/251 (26%)

Query: 215 KRASTMPRLDPPEDKTI-TTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQ 273
           +R   +P++ P       TTL+VG L    T+ D+ +   +FG I +I ++  + CA+I 
Sbjct: 475 RRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIV 534

Query: 274 FATRQAAEVAAEK-SFNKLIVNGRRLNVKWGRSQAARGKEKE------------------ 314
              RQ A  A +K S     VN + + + W  ++  +   K+                  
Sbjct: 535 MVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKP 594

Query: 315 -------KDGTTDS--------GI-----------------KLEPVPGLPGALP---PPP 339
                  + G  DS        GI                   EPV  +P  LP   PP 
Sbjct: 595 EELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 654

Query: 340 AAEEEASANYFNLPP--SGPPAVVNIALPPPPGIAPP---PPPGFGPHMFHPMGPPPPFM 394
                 +     +PP   GPP V  +    PP   PP   PPPGFGP +  P  PPPPF+
Sbjct: 655 PVPAPITVPPPQVPPHQPGPPVVGAL---QPPAFTPPLGIPPPGFGPGV-PPPPPPPPFL 710

Query: 395 RAPG--PIHYP 403
           R PG  P+H P
Sbjct: 711 R-PGFNPMHLP 720



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 41/143 (28%), Positives = 49/143 (34%), Gaps = 33/143 (23%)

Query: 308 ARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVN----- 362
           ARG  +  D     G  + P    P  LP PP  +  +      + P GP   +      
Sbjct: 777 ARGNAESGDSVKMYGSAVPPAA--PTNLPTPPVTQPVSLLGTQGVAP-GPVIGLQAPSTG 833

Query: 363 --------IALPPPPGIAPP--------PPPGFGPHMFH---PMG------PPPPFMRAP 397
                   I L  PPG+ PP        PP    PHM H   P G      PPP  M+ P
Sbjct: 834 LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP 893

Query: 398 GPIHYPSQDPQRMGAHAGKHSSP 420
            P H P   P  M    G    P
Sbjct: 894 FPPHGPFVRPGGMPGLGGPGPGP 916



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 12/75 (16%)

Query: 326 EPVPGLPGALPPP----PAAEEEASANYFNLPPSGPPAVVNIALPP---PPG-IAPPPPP 377
           +P P + GAL PP    P             PP  PP  +     P   PPG + P PPP
Sbjct: 671 QPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPP 730

Query: 378 GFGPHMFHPMGPPPP 392
              P    P+  PPP
Sbjct: 731 PITP----PVSIPPP 741



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 10/53 (18%)

Query: 329 PGLPGALPPPPAAEEEASANYFNLPPS----GPPAVVNIALPPPPGIAPPPPP 377
           PG+P   PPPP        N  +LPP     GPP  +     PP  I PP  P
Sbjct: 698 PGVPPPPPPPPFLRP--GFNPMHLPPGFLPPGPPPPIT----PPVSIPPPHTP 744


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 70/251 (27%), Positives = 100/251 (39%), Gaps = 67/251 (26%)

Query: 215 KRASTMPRLDPPEDKTI-TTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQ 273
           +R   +P++ P       TTL+VG L    T+ D+ +   +FG I +I ++  + CA+I 
Sbjct: 490 RRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIV 549

Query: 274 FATRQAAEVAAEK-SFNKLIVNGRRLNVKWGRSQAARGKEKE------------------ 314
              RQ A  A +K S     VN + + + W  ++  +   K+                  
Sbjct: 550 MVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKP 609

Query: 315 -------KDGTTDS--------GI-----------------KLEPVPGLPGALP---PPP 339
                  + G  DS        GI                   EPV  +P  LP   PP 
Sbjct: 610 EELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 669

Query: 340 AAEEEASANYFNLPP--SGPPAVVNIALPPPPGIAPP---PPPGFGPHMFHPMGPPPPFM 394
                 +     +PP   GPP V  +    PP   PP   PPPGFGP +  P  PPPPF+
Sbjct: 670 PVPAPITVPPPQVPPHQPGPPVVGAL---QPPAFTPPLGIPPPGFGPGV-PPPPPPPPFL 725

Query: 395 RAPG--PIHYP 403
           R PG  P+H P
Sbjct: 726 R-PGFNPMHLP 735



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 41/143 (28%), Positives = 49/143 (34%), Gaps = 33/143 (23%)

Query: 308 ARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVN----- 362
           ARG  +  D     G  + P    P  LP PP  +  +      + P GP   +      
Sbjct: 792 ARGNAESGDSVKMYGSAVPPAA--PTNLPTPPVTQPVSLLGTQGVAP-GPVIGLQAPSTG 848

Query: 363 --------IALPPPPGIAPP--------PPPGFGPHMFH---PMG------PPPPFMRAP 397
                   I L  PPG+ PP        PP    PHM H   P G      PPP  M+ P
Sbjct: 849 LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP 908

Query: 398 GPIHYPSQDPQRMGAHAGKHSSP 420
            P H P   P  M    G    P
Sbjct: 909 FPPHGPFVRPGGMPGLGGPGPGP 931



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 12/75 (16%)

Query: 326 EPVPGLPGALPPP----PAAEEEASANYFNLPPSGPPAVVNIALPP---PPG-IAPPPPP 377
           +P P + GAL PP    P             PP  PP  +     P   PPG + P PPP
Sbjct: 686 QPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPP 745

Query: 378 GFGPHMFHPMGPPPP 392
              P    P+  PPP
Sbjct: 746 PITP----PVSIPPP 756



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 10/53 (18%)

Query: 329 PGLPGALPPPPAAEEEASANYFNLPPS----GPPAVVNIALPPPPGIAPPPPP 377
           PG+P   PPPP        N  +LPP     GPP  +     PP  I PP  P
Sbjct: 713 PGVPPPPPPPPFLRP--GFNPMHLPPGFLPPGPPPPIT----PPVSIPPPHTP 759


>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
          Length = 1271

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 61/235 (25%), Positives = 92/235 (39%), Gaps = 58/235 (24%)

Query: 223 LDPPEDKTI----TTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQ 278
           L P   KT+    TTL+VG +    T+ DL N F +FG+I +I ++  + CA++    RQ
Sbjct: 464 LPPIRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFGQIESINMIPPRGCAYVCMVHRQ 523

Query: 279 AAEVAAEK-SFNKLIVNGRRLNVKWGRSQAARGKEK--------------------EKDG 317
            A  A +K S     +  + + + W  ++  + + K                    + +G
Sbjct: 524 DAFRALQKLSSGSYKIGSKVIKIAWALNKGVKTEYKQFWDVDLGVTYIPWEKVKVDDLEG 583

Query: 318 TTDSGI--------------KLEPVPGLPGALPPPPAAEEE----ASANYFNLP------ 353
             + G+                EPV         P   E+E      A  F  P      
Sbjct: 584 FAEGGMIDQETVNTEWETVKSSEPVKETVQTTQSPTPVEKETVVTTQAEVFPPPVAMLQI 643

Query: 354 PSGP--------PAVVNIALP-PPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGP 399
           P  P        P    +++P PPPG +P PPP F    F+P  PPP FM  P P
Sbjct: 644 PVAPAVPTVSLVPPAFPVSMPVPPPGFSPIPPPPFLRASFNPSQPPPGFMPPPVP 698



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 21/50 (42%), Positives = 22/50 (44%), Gaps = 1/50 (2%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP 376
           PVP  PG  P PP     AS N    PP   P  V   + PPP I P  P
Sbjct: 664 PVPP-PGFSPIPPPPFLRASFNPSQPPPGFMPPPVPPPVVPPPTIPPVVP 712


>gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]
          Length = 378

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 56/217 (25%), Positives = 89/217 (41%), Gaps = 35/217 (16%)

Query: 221 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV---QRQQ---CAFIQF 274
           PR D  +   I   +VGG+     ET+LR +F +FG +  + ++   ++Q+     FI F
Sbjct: 105 PRSDNSKSNKI---FVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITF 161

Query: 275 ATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGA 334
              Q+ + A    F+ ++  G+++ VK    + ++ +   + G +  G ++ P      A
Sbjct: 162 EDEQSVDQAVNMHFHDIM--GKKVEVKRAEPRDSKSQAPGQPGASQWGSRVVPNAANGWA 219

Query: 335 LPPPPAAEEEASANYFNLPPS------GPPAVVNIALPPPPG----IAPPPPPGFGPHMF 384
             PPP  ++        +P        GPP     A PPPP     I   PP GF P   
Sbjct: 220 GQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQG 279

Query: 385 HPMG--------------PPPPFMRAPGPIHYPSQDP 407
            P G              PPPP   AP  +  P   P
Sbjct: 280 FPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATP 316



 Score = 33.9 bits (76), Expect = 0.28
 Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 26/76 (34%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP------------------------GI 371
           PPPP  ++ A       PP   P    +A PPPP                        G 
Sbjct: 296 PPPPPPDQFAPPGV--PPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYGLGS 353

Query: 372 APPPPPGFGPHMFHPM 387
             P PPG GPH  + +
Sbjct: 354 YSPAPPGCGPHFVYSL 369



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 13/28 (46%), Positives = 20/28 (71%)

Query: 231 ITTLYVGGLGDTITETDLRNHFYQFGEI 258
           I  L+VGGL  + T+  LR++F Q+GE+
Sbjct: 9   IGKLFVGGLDWSTTQETLRSYFSQYGEV 36


>gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]
          Length = 407

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 56/217 (25%), Positives = 89/217 (41%), Gaps = 35/217 (16%)

Query: 221 PRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV---QRQQ---CAFIQF 274
           PR D  +   I   +VGG+     ET+LR +F +FG +  + ++   ++Q+     FI F
Sbjct: 105 PRSDNSKSNKI---FVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITF 161

Query: 275 ATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGA 334
              Q+ + A    F+ ++  G+++ VK    + ++ +   + G +  G ++ P      A
Sbjct: 162 EDEQSVDQAVNMHFHDIM--GKKVEVKRAEPRDSKSQAPGQPGASQWGSRVVPNAANGWA 219

Query: 335 LPPPPAAEEEASANYFNLPPS------GPPAVVNIALPPPPG----IAPPPPPGFGPHMF 384
             PPP  ++        +P        GPP     A PPPP     I   PP GF P   
Sbjct: 220 GQPPPTWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPPPFTSYIVSTPPGGFPPPQG 279

Query: 385 HPMG--------------PPPPFMRAPGPIHYPSQDP 407
            P G              PPPP   AP  +  P   P
Sbjct: 280 FPQGYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATP 316



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 27/103 (26%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPP----PP--------------- 376
           PPPP  ++ A       PP   P    +A PPPP  A P    PP               
Sbjct: 296 PPPPPPDQFAPPGV--PPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQPDFPYGQYAGYG 353

Query: 377 ---PGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGK 416
               GFG     P   PP +    GP    S  P   G+  G+
Sbjct: 354 QDLSGFGQGFSDPSQQPPSY---GGPSVPGSGGPPAGGSGFGR 393



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 13/28 (46%), Positives = 20/28 (71%)

Query: 231 ITTLYVGGLGDTITETDLRNHFYQFGEI 258
           I  L+VGGL  + T+  LR++F Q+GE+
Sbjct: 9   IGKLFVGGLDWSTTQETLRSYFSQYGEV 36


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 56/204 (27%), Positives = 76/204 (37%), Gaps = 29/204 (14%)

Query: 234 LYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ-------CAFIQFATRQAAEVAAEK 286
           +++G L   I E  L + F  FG I     + R          AFI FA+  A++ A E 
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161

Query: 287 SFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKL---------EPVPGLPGALPP 337
              + + N R + V +   + ++G   E+ G+    +            P      A PP
Sbjct: 162 MNGQYLCN-RPITVSYAFKKDSKG---ERHGSAAERLLAAQNPLSQADRPHQLFADAPPP 217

Query: 338 PPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPP-PPPGFGPHMFHPMGPPPPFMRA 396
           P A     S+    LPP G        +PPP    PP PPPG  P    P  PPPP    
Sbjct: 218 PSAPNPVVSSLGSGLPPPG--------MPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPG 269

Query: 397 PGPIHYPSQDPQRMGAHAGKHSSP 420
                 PS      G     HS P
Sbjct: 270 AAGHGPPSAGTPGAGHPGHGHSHP 293



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 15/85 (17%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALP---PPPGIAPPPPPGFGPHM 383
           P PG+P   PPP             +PP GPP    +  P   PP G+  PPP    PH 
Sbjct: 337 PPPGMPHPGPPP-----------MGMPPRGPPFGSPMGHPGPMPPHGMRGPPPL-MPPHG 384

Query: 384 FHPMGPPPPFMRAPGPIHYPSQDPQ 408
           +     PPP+    GP+  P   P+
Sbjct: 385 YTGPPRPPPYGYQRGPLPPPRPTPR 409



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 13/90 (14%)

Query: 327 PVPGLPGALPPPPAAEEEAS---ANYFNLPPSGPPAVVNIALP-PPPGIAPPPPPG---- 378
           P P  PG +P P  ++ + +    +    P +GPP       P PPPG+  P PP     
Sbjct: 293 PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMP 352

Query: 379 -----FGPHMFHPMGPPPPFMRAPGPIHYP 403
                FG  M HP   PP  MR P P+  P
Sbjct: 353 PRGPPFGSPMGHPGPMPPHGMRGPPPLMPP 382



 Score = 36.2 bits (82), Expect = 0.057
 Identities = 36/125 (28%), Positives = 44/125 (35%), Gaps = 34/125 (27%)

Query: 329 PGLPGALPPPPAAEEEAS------------------ANYFNLPPSGPP----AVVNIAL- 365
           PG+P A+PPPP     A                   ++    PP G P    + + +A  
Sbjct: 255 PGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314

Query: 366 ---------PPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPG-PIHYPSQDPQRMGAHAG 415
                      PPG    PPP   P M HP GPPP  M   G P   P   P  M  H  
Sbjct: 315 GPHGLGHPHAGPPGSGGQPPPRPPPGMPHP-GPPPMGMPPRGPPFGSPMGHPGPMPPHGM 373

Query: 416 KHSSP 420
           +   P
Sbjct: 374 RGPPP 378



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 7/74 (9%)

Query: 233 TLYVGGLGDTITETDLRNHFYQFGEI------RTITVVQRQQCAFIQFATRQAAEVAAEK 286
           T+YVGGL + ++E  L   F Q G +      +     Q Q   F++F + + A+ A  K
Sbjct: 14  TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAI-K 72

Query: 287 SFNKLIVNGRRLNV 300
             N + + G+ + V
Sbjct: 73  IMNMIKLYGKPIRV 86


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 30/77 (38%), Positives = 35/77 (45%), Gaps = 15/77 (19%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHP 386
           P PG P  LPP P             PP GPP    +  P PPGI PP P    P +  P
Sbjct: 470 PPPGPPPGLPPGP-------------PPRGPPP--RLPPPAPPGIPPPRPGMMRPPLVPP 514

Query: 387 MGPPPPFMRAPGPIHYP 403
           +GP PP +  P P+  P
Sbjct: 515 LGPAPPGLFPPAPLPNP 531



 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 41/129 (31%), Positives = 48/129 (37%), Gaps = 24/129 (18%)

Query: 303 GRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVN 362
           G S A+  ++        S I+  P+PG P  L PPPA           LPP  PP    
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPG-PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPP 440

Query: 363 IALPP-----------------PPGIAPPPPPGFGPHMFHPMGP----PPPFMRAPGPIH 401
              PP                 PPG  P PPPG  P +  P GP    PPP +  P P  
Sbjct: 441 FLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGL--PPGPPPRGPPPRLPPPAPPG 498

Query: 402 YPSQDPQRM 410
            P   P  M
Sbjct: 499 IPPPRPGMM 507



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 24/111 (21%)

Query: 304 RSQAARGKEKEKDGTTDSGIKLEPVPGL--PGALPPPPAAEEEASANYFNLPPSGPPAVV 361
           +SQ    +E   DGT+ +  + +  P    P  +  PP             PP GPP   
Sbjct: 369 QSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGP---------PPLGPPPAP 419

Query: 362 NIALPPPPGIAPPPPPGFGPHMFHPMG-------------PPPPFMRAPGP 399
            +  P PP   PP PP   P    P G             P PP  R PGP
Sbjct: 420 PLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP 470



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 27/80 (33%)

Query: 321 SGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALP--------PPPGIA 372
           S I ++ +P LPGA PP    +  A          GPP      LP         PPG  
Sbjct: 149 SNILIQDIP-LPGAQPPSILKKTSAY---------GPPTRAVSILPLLGHGVPRLPPGRK 198

Query: 373 PPPPPGFGPHMFHPMGPPPP 392
           PP P         P GPPPP
Sbjct: 199 PPGP---------PPGPPPP 209


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 39/100 (39%), Positives = 45/100 (45%), Gaps = 15/100 (15%)

Query: 327 PVPGLPGALPP-----PPAAEEEASANYFNLP---PSGPPAVVNIALPPPPGIAPPPPPG 378
           P PG+ G+ PP     PPA    + A   + P   P+ PPAV +     PPG  PP PP 
Sbjct: 117 PAPGV-GSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA----PPGAPPPTPPS 171

Query: 379 FGPHMFHPM--GPPPPFMRAPGPIHYPSQDPQRMGAHAGK 416
            G     P   GPPPP    PGP   P Q P   G   GK
Sbjct: 172 SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 226 PEDKTITT---LYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEV 282
           P +KT T    L+VG L   ITE + +  F ++GE   + + + +   FI+  +R  AE+
Sbjct: 288 PGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEI 347

Query: 283 AAEKSFNKLIVNGRRLNVKWGRSQAA 308
            A+   +   + GR+L V++    AA
Sbjct: 348 -AKAELDDTPMRGRQLRVRFATHAAA 372



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 16/97 (16%)

Query: 327 PVPGLPGA---LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHM 383
           P PG  G    +PPPP  +++        PP  PP         PP   PPP P   PH 
Sbjct: 49  PGPGQSGPKPPIPPPPPHQQQQQP-----PPQQPPP------QQPPPHQPPPHP--QPHQ 95

Query: 384 FHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP 420
                PPP     P     P   P    A     S+P
Sbjct: 96  QQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP 132



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 26/76 (34%), Positives = 27/76 (35%), Gaps = 12/76 (15%)

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP---------PGFGPH 382
           PG  P PP A   A       PP  PP+      PP  G  PPPP         P  GP 
Sbjct: 147 PGPTPTPPPAVTSAPPG---APPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203

Query: 383 MFHPMGPPPPFMRAPG 398
              P G   P    PG
Sbjct: 204 PGGPKGGKMPGGPKPG 219


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 34/135 (25%)

Query: 273 QFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPV-PGL 331
           +F  RQ A+   +K   K         +K   ++  + + + +  ++ SGI   P  P L
Sbjct: 507 EFTARQEAQAELQKRDEK---------IKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPL 557

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------GIAPPPPPGFGPHMF 384
           PG  PPPP              P  PP      LPPPP       GI PPPPP   P +F
Sbjct: 558 PGVGPPPP--------------PPAPPLPGGAPLPPPPPPLPGMMGIPPPPPP---PLLF 600

Query: 385 HPMGPPPPFMRAPGP 399
               PPPP    P P
Sbjct: 601 GGPPPPPPLGGVPPP 615



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 327 PVPGLPGA--LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGI-APPPPPGFGPHM 383
           P P LPG   LPPPP            +PP  PP ++    PPPP +   PPPPG   ++
Sbjct: 567 PAPPLPGGAPLPPPPPP----LPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNL 622

Query: 384 FHPM 387
            + M
Sbjct: 623 PYGM 626



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 10/54 (18%)

Query: 356 GPPAVVNIALPPPPGIAPPPPPGFGPHM--FHPMGPPPPFMRAPGPIHYPSQDP 407
           GPPA      PP PG+  PPPP   P +    P+ PPPP +  PG +  P   P
Sbjct: 550 GPPAA-----PPLPGV-GPPPPPPAPPLPGGAPLPPPPPPL--PGMMGIPPPPP 595


>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
          Length = 1101

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 34/135 (25%)

Query: 273 QFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPV-PGL 331
           +F  RQ A+   +K   K         +K   ++  + + + +  ++ SGI   P  P L
Sbjct: 507 EFTARQEAQAELQKRDEK---------IKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPL 557

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------GIAPPPPPGFGPHMF 384
           PG  PPPP              P  PP      LPPPP       GI PPPPP   P +F
Sbjct: 558 PGVGPPPP--------------PPAPPLPGGAPLPPPPPPLPGMMGIPPPPPP---PLLF 600

Query: 385 HPMGPPPPFMRAPGP 399
               PPPP    P P
Sbjct: 601 GGPPPPPPLGGVPPP 615



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 327 PVPGLPGA--LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGI-APPPPPGFGPHM 383
           P P LPG   LPPPP            +PP  PP ++    PPPP +   PPPPG   ++
Sbjct: 567 PAPPLPGGAPLPPPPPP----LPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNL 622

Query: 384 FHPM 387
            + M
Sbjct: 623 PYGM 626



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 10/54 (18%)

Query: 356 GPPAVVNIALPPPPGIAPPPPPGFGPHM--FHPMGPPPPFMRAPGPIHYPSQDP 407
           GPPA      PP PG+  PPPP   P +    P+ PPPP +  PG +  P   P
Sbjct: 550 GPPAA-----PPLPGV-GPPPPPPAPPLPGGAPLPPPPPPL--PGMMGIPPPPP 595


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 72/283 (25%), Positives = 106/283 (37%), Gaps = 51/283 (18%)

Query: 174 KRGEECPYRHEKPTDPDDPLADQNIKD------RYYG--INDPVADKLLKRASTMP-RLD 224
           +R  +   R + P  P+ P+A  +IK+      R+YG  +N+    K  K+      RL 
Sbjct: 140 RRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLT 199

Query: 225 PPEDKTITTL-YVGGLG-DTITETDLRN------HFYQFGEIRTITVVQRQQCAFIQFAT 276
             +  T +   ++G +G D  T  DL N      + +    I    +  R+    I    
Sbjct: 200 KADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFI 259

Query: 277 RQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALP 336
            +   V A K       N  R         +  G         +SG    P  G  GA P
Sbjct: 260 EKTGGVEAVK-------NELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGR-GAPP 311

Query: 337 PPPAAEEEASANYFNLPPSGPPAVVNIALPPPPG--IAPPPPP----------------- 377
           PPP+    A+      PP  PP+  ++A+PPPP   + PPPPP                 
Sbjct: 312 PPPSRAPTAA------PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSV 365

Query: 378 -GFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSS 419
            G GP    P  PPPP    P P   PS    ++   AG  ++
Sbjct: 366 LGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAA 408


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 12/87 (13%)

Query: 317 GTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP 376
           GT   G+   P   LP   PPPP  + E       LPP  P       + PPP   PPPP
Sbjct: 540 GTGGGGLPAPPDDFLPPPPPPPPLDDPE-------LPPPPPDF-----MEPPPDFVPPPP 587

Query: 377 PGFGPHMFHPMGPPPPFMRAPGPIHYP 403
           P +       + PPPP   AP P   P
Sbjct: 588 PSYAGIAGSELPPPPPPPPAPAPAPVP 614



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/120 (31%), Positives = 43/120 (35%), Gaps = 6/120 (5%)

Query: 306 QAARGKEKEKDGTTDSGIKLEP-VPGLPGA----LPPPPAAEEEASANYFNLPPSGPPAV 360
           +A R  E  KD     G   +P VP  P A    LPPPP     +  +     P      
Sbjct: 482 EAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGT 541

Query: 361 VNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP 420
               LP PP    PPPP   P     + PPPP    P P   P   P   G  AG    P
Sbjct: 542 GGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGI-AGSELPP 600


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 35/90 (38%), Positives = 39/90 (43%), Gaps = 19/90 (21%)

Query: 327  PVPGLPGA----LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPG-----IAPPPPP 377
            P+PGLP A     P PP  EE+        PP+ PPA      PPPP        P PPP
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKP-------PPTPPPAPTPQPQPPPPPPPPQPALPSPPP 1487

Query: 378  GFGPHMFHPMGPPPPFMRAPGPIHYPSQDP 407
               P    P  PPPP +  P P   PS  P
Sbjct: 1488 LVAP---TPSSPPPPPLPPPPPPAMPSPPP 1514



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 29/75 (38%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 327  PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHP 386
            P P LP   PPP  A   +S     LPP  PPA+ +   PPPP  AP   P   P    P
Sbjct: 1478 PQPALPS--PPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535

Query: 387  MGPPPPFMRAPGPIH 401
              P  P  R   P+H
Sbjct: 1536 EDPELPDTR---PLH 1547



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 37/132 (28%), Positives = 48/132 (36%), Gaps = 29/132 (21%)

Query: 311 KEKEKDGTTDSGIKLEPVPGLPGAL-----------PPPPAAEEEASANYFNLPPSGPPA 359
           K  E+ G T  G+    V    GA            PPPP A+      +  L  +G P 
Sbjct: 730 KGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPD 789

Query: 360 VVNIALPPPPGI-------APPPPPG---FGPHMFHPM----GPPPPFMRAPGPIHYPSQ 405
           +  +  PPPP +       AP P P     G H+  P      P PP    P P   P  
Sbjct: 790 LPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPP----PPPPPPPPP 845

Query: 406 DPQRMGAHAGKH 417
            P ++ AH   H
Sbjct: 846 MPLQLEAHLRSH 857



 Score = 33.9 bits (76), Expect = 0.28
 Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 10/95 (10%)

Query: 314  EKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAP 373
            E+D    +    E +     AL  PP A  + ++      P GPP     A+P      P
Sbjct: 1384 EEDSVAKNRDLQESISSAISALDDPPLAGPKDTST-----PDGPPLAPAAAVP-----GP 1433

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQ 408
            PP PG      +    PP     P P   P+  PQ
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

Query: 329  PGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP 376
            PGL      PP      +A    L  SGP    + A PPPP   PPPP
Sbjct: 1006 PGLGLDPNKPPELPSTVNAEPLGLIQSGP----HQAAPPPPPPPPPPP 1049



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 19/102 (18%)

Query: 312  EKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANY-----FNLPPSGPPAVVNIALP 366
            E E D    +G    P PG P   P  P     AS          L P+ PP + +    
Sbjct: 969  EDEGDPKAGAG----PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNA 1024

Query: 367  PPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQ 408
             P G+        GPH   P  PPPP    P P   P+ +P+
Sbjct: 1025 EPLGLIQS-----GPHQAAPPPPPPP---PPPPA--PASEPK 1056



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 27/91 (29%), Positives = 31/91 (34%), Gaps = 29/91 (31%)

Query: 329 PGLPGALPPP----------------PAAEEEASANYFNLPPSGPPAVVNIALPPPPGIA 372
           PG P   PPP                 AA E++S   +N   + P        PPPP  A
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPG-------PPPPERA 281

Query: 373 PPPPPGFGPHMFHPMG--PPPPFMRAPGPIH 401
            P       H   P    PPPP    P P H
Sbjct: 282 LPRQDTVIKHYQRPASAQPPPP----PPPAH 308



 Score = 28.9 bits (63), Expect = 9.1
 Identities = 31/102 (30%), Positives = 38/102 (37%), Gaps = 9/102 (8%)

Query: 327 PVPGLPGALPPP---PAAEEEASANYFNLPPSGPPAVVN-IALPPPPGIAPPPPPGFGPH 382
           PVP       PP   PA    +  +  +L PS  P V + +      G     P G GP 
Sbjct: 163 PVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPA 222

Query: 383 MFHPMGPPPPFMRAPGPIHYPSQ----DPQRMGAHAGKHSSP 420
              P  P PP    P P H P+Q          A A + SSP
Sbjct: 223 QTPPYRPGPP-DPPPPPRHLPTQFNLLASSSAAAAAAEQSSP 263


>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
          Length = 465

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/278 (25%), Positives = 101/278 (36%), Gaps = 73/278 (26%)

Query: 198 IKDRYYGINDPVA-------DKLLKRAS------TMPRLDPP------------EDKTIT 232
           IKD+Y G++   A       D  LK  S      T+P ++ P            ED+   
Sbjct: 39  IKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRK-- 96

Query: 233 TLYVGGLGDTITETDLRNHFYQFGEIRTITVVQ-----RQQCAFIQFATRQAAEVAAEKS 287
            L+VG LG   T+ D+R  F  FG I   TV++      + CAF++F T   A+ A    
Sbjct: 97  -LFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTL 155

Query: 288 FNKLIVNG--RRLNVKWGRSQAARGKEKEKDGTTDSG------IKLEPVPGLPGALPPPP 339
            +   + G    L VK+  ++  RG  + +   T  G      ++         AL    
Sbjct: 156 HSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQ 215

Query: 340 AAEEEASANYFNLPPSGPPAVVN------------IALPPPPGIAPPPPP---------- 377
           AA   A + Y  L P    A V             IA P  P      PP          
Sbjct: 216 AALVAAHSAY--LSPMATMAAVQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAI 273

Query: 378 -------GFGPHMFHPMGPPPPFMRAPGPIH-YPSQDP 407
                  G+ P    P G P P    P  +H YP+Q P
Sbjct: 274 PAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSP 311



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 9/89 (10%)

Query: 234 LYVGGLGDTITETDLRNHFYQFGEIRTITVVQ------RQQCAFIQFATRQAAEVAAEKS 287
           L+VG +   + E DL+  F QFG I  +TV++       + CAF+ +  R +A  A    
Sbjct: 9   LFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSAL 68

Query: 288 FNKLIVNG--RRLNVKWGRSQAARGKEKE 314
             +  + G  R + VK   S+ +RG++++
Sbjct: 69  HEQKTLPGMNRPIQVKPADSE-SRGEDRK 96



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 3/56 (5%)

Query: 325 LEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIA---PPPPP 377
           + P P    A P  P  +  A   ++        ++V  A P PP +    PPPPP
Sbjct: 303 VHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPP 358


>gi|206597502 NESH protein isoform 2 [Homo sapiens]
          Length = 360

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 13/104 (12%)

Query: 291 LIVNGRRLNVKWGRSQAARGKEKEKDGT-TDSGIKLEPVPGLPGAL--PPPPAAEE---- 343
           ++ +GR        S A+ G  +   G  T  G    P P LP +L  PPPPAA E    
Sbjct: 190 VVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQR 249

Query: 344 EASANYFNLPPSGPPAVVNIALPPPPGI------APPPPPGFGP 381
             +    + PP      + + LPPPP +       PPPPPGFGP
Sbjct: 250 PPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGP 293



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 25/92 (27%), Positives = 33/92 (35%), Gaps = 16/92 (17%)

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAP----------PPPPGFGP 381
           P  LP  P     A+++  +L  +G    V  A  P    AP          PPPP    
Sbjct: 185 PVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAV 244

Query: 382 HMF------HPMGPPPPFMRAPGPIHYPSQDP 407
            +F        + PPPP    P P+  P   P
Sbjct: 245 EVFQRPPTLEELSPPPPDEELPLPLDLPPPPP 276


>gi|7705981 NESH protein isoform 1 [Homo sapiens]
          Length = 366

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 13/104 (12%)

Query: 291 LIVNGRRLNVKWGRSQAARGKEKEKDGT-TDSGIKLEPVPGLPGAL--PPPPAAEE---- 343
           ++ +GR        S A+ G  +   G  T  G    P P LP +L  PPPPAA E    
Sbjct: 196 VVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQR 255

Query: 344 EASANYFNLPPSGPPAVVNIALPPPPGI------APPPPPGFGP 381
             +    + PP      + + LPPPP +       PPPPPGFGP
Sbjct: 256 PPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGP 299



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 25/92 (27%), Positives = 33/92 (35%), Gaps = 16/92 (17%)

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAP----------PPPPGFGP 381
           P  LP  P     A+++  +L  +G    V  A  P    AP          PPPP    
Sbjct: 191 PVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAV 250

Query: 382 HMF------HPMGPPPPFMRAPGPIHYPSQDP 407
            +F        + PPPP    P P+  P   P
Sbjct: 251 EVFQRPPTLEELSPPPPDEELPLPLDLPPPPP 282


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 35/86 (40%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 322 GIKLEPVP---GLPGALPPPPAAEEEASANYFNLPPSGPPAVVNI-ALPPPP-----GIA 372
           GI   P P   G PG  PPP         ++   PP  PP   +   LPPPP     G A
Sbjct: 331 GIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGA 390

Query: 373 PPPPPGFGPHMFHPMGPPPPFMRAPG 398
           PPPPP   P    P  PPPPF  A G
Sbjct: 391 PPPPPPPPP----PGPPPPPFTGADG 412



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 8/85 (9%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHP 386
           P P + G  PPPP     +       PP  PP+      PP P  A PPPP   P   +P
Sbjct: 325 PPPPMIGIPPPPPPVGFGSPGTP---PPPSPPS-----FPPHPDFAAPPPPPPPPAADYP 376

Query: 387 MGPPPPFMRAPGPIHYPSQDPQRMG 411
             PPPP  +  G    P   P   G
Sbjct: 377 TLPPPPLSQPTGGAPPPPPPPPPPG 401



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/99 (35%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP--GIAPPPPP-GFG-----PHMFHPM 387
           P PP          F  PP+ PP       PPPP  GI PPPPP GFG     P    P 
Sbjct: 302 PAPPLGSPPGPKPGFAPPPAPPP-------PPPPMIGIPPPPPPVGFGSPGTPPPPSPPS 354

Query: 388 GPPPPFMRAPGP------IHYPSQDPQRMGAHAGKHSSP 420
            PP P   AP P        YP+  P  +    G    P
Sbjct: 355 FPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 29/92 (31%), Positives = 33/92 (35%), Gaps = 13/92 (14%)

Query: 335 LPPPPAAEEEASANYFN-----------LPPSGPPAVVNIALP--PPPGIAPPPPPGFGP 381
           LPPPPA       N              + PS PP    +  P  P PG APPP P   P
Sbjct: 267 LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP 326

Query: 382 HMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAH 413
                + PPPP +    P   P   P     H
Sbjct: 327 PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH 358



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 8/73 (10%)

Query: 327 PVPGLPGALPP------PPAAEEEASANYFNLPPS--GPPAVVNIALPPPPGIAPPPPPG 378
           P P  P + PP      PP      +A+Y  LPP     P       PPPP    PPPP 
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406

Query: 379 FGPHMFHPMGPPP 391
           F      P  PPP
Sbjct: 407 FTGADGQPAIPPP 419


>gi|4507127 small nuclear ribonucleoprotein polypeptide C [Homo
           sapiens]
          Length = 159

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 7/112 (6%)

Query: 301 KWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGA---LPPPPAAEEEASANYFNLPPSGP 357
           KW   QA    +K         I   P    P A   +PPPP+            P  G 
Sbjct: 40  KWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGG 99

Query: 358 PAVVNIALPPPPGIAP-PPPPGFGPHM--FHPMGPPPPFMRAPG-PIHYPSQ 405
           P ++ +  PPPPG+ P  P PG  P M    PM P PP MR P  P+  P++
Sbjct: 100 PPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTR 151



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/88 (38%), Positives = 38/88 (43%), Gaps = 25/88 (28%)

Query: 333 GALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGF-------GPHMFH 385
           G +PP P          F+ PP   PA     +PPPP +  PP PG        GP M  
Sbjct: 60  GKIPPTP----------FSAPP---PA--GAMIPPPPSLPGPPRPGMMPAPHMGGPPMMP 104

Query: 386 PMGPPPPFMRAPGPIHYPSQDPQRMGAH 413
            MGPPPP M   GP   P   P  MG H
Sbjct: 105 MMGPPPPGMMPVGPA--PGMRPP-MGGH 129


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 34/77 (44%), Positives = 36/77 (46%), Gaps = 22/77 (28%)

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP-PGFGPHMFHPMGPP 390
           P A PPPP            LPP   PA  ++ALPPPPG  PPPP P  GP    P  PP
Sbjct: 310 PLAPPPPPP-----------LPPG--PAQASVALPPPPGPPPPPPLPSTGP----PPPPP 352

Query: 391 PPFMRAPGPIHYPSQDP 407
           PP    P P   P   P
Sbjct: 353 PP----PLPNQVPPPPP 365



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 33/79 (41%), Positives = 36/79 (45%), Gaps = 17/79 (21%)

Query: 319 TDSGIKLEPV-PGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP----GIAP 373
           +  GI L P+ P  P  LPP PA    A       PP GPP       PPPP    G  P
Sbjct: 302 SQQGIVLGPLAPPPPPPLPPGPAQASVALP-----PPPGPP-------PPPPLPSTGPPP 349

Query: 374 PPPPGFGPHMFHPMGPPPP 392
           PPPP   P+   P  PPPP
Sbjct: 350 PPPPPPLPNQVPPPPPPPP 368



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 6/62 (9%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMR 395
           PPPP     A A+    PP GPP       PP P   PPPPP   P + + + PPPP   
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPP-----PPLPSTGPPPPPP-PPPLPNQVPPPPPPPP 368

Query: 396 AP 397
           AP
Sbjct: 369 AP 370



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 9/64 (14%)

Query: 317 GTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP 376
           G   + + L P PG P   PPPP             PP  PP + N   PPPP    PP 
Sbjct: 322 GPAQASVALPPPPGPP---PPPPLPSTGPP------PPPPPPPLPNQVPPPPPPPPAPPL 372

Query: 377 PGFG 380
           P  G
Sbjct: 373 PASG 376



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 15/65 (23%)

Query: 354 PSGPPAVVNIALPPPPGIAP----------PPPPGFGPHMFHP-MGPPPPFMRAPGPIHY 402
           PS    V+    PPPP   P          PPPPG  P    P  GPPPP    P P   
Sbjct: 301 PSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----PPPPPL 356

Query: 403 PSQDP 407
           P+Q P
Sbjct: 357 PNQVP 361


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 34/77 (44%), Positives = 36/77 (46%), Gaps = 22/77 (28%)

Query: 332 PGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP-PGFGPHMFHPMGPP 390
           P A PPPP            LPP   PA  ++ALPPPPG  PPPP P  GP    P  PP
Sbjct: 310 PLAPPPPPP-----------LPPG--PAQASVALPPPPGPPPPPPLPSTGP----PPPPP 352

Query: 391 PPFMRAPGPIHYPSQDP 407
           PP    P P   P   P
Sbjct: 353 PP----PLPNQVPPPPP 365



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 33/79 (41%), Positives = 36/79 (45%), Gaps = 17/79 (21%)

Query: 319 TDSGIKLEPV-PGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP----GIAP 373
           +  GI L P+ P  P  LPP PA    A       PP GPP       PPPP    G  P
Sbjct: 302 SQQGIVLGPLAPPPPPPLPPGPAQASVALP-----PPPGPP-------PPPPLPSTGPPP 349

Query: 374 PPPPGFGPHMFHPMGPPPP 392
           PPPP   P+   P  PPPP
Sbjct: 350 PPPPPPLPNQVPPPPPPPP 368



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 6/62 (9%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMR 395
           PPPP     A A+    PP GPP       PP P   PPPPP   P + + + PPPP   
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPP-----PPLPSTGPPPPPP-PPPLPNQVPPPPPPPP 368

Query: 396 AP 397
           AP
Sbjct: 369 AP 370



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 9/64 (14%)

Query: 317 GTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPP 376
           G   + + L P PG P   PPPP             PP  PP + N   PPPP    PP 
Sbjct: 322 GPAQASVALPPPPGPP---PPPPLPSTGPP------PPPPPPPLPNQVPPPPPPPPAPPL 372

Query: 377 PGFG 380
           P  G
Sbjct: 373 PASG 376



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 15/65 (23%)

Query: 354 PSGPPAVVNIALPPPPGIAP----------PPPPGFGPHMFHP-MGPPPPFMRAPGPIHY 402
           PS    V+    PPPP   P          PPPPG  P    P  GPPPP    P P   
Sbjct: 301 PSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----PPPPPL 356

Query: 403 PSQDP 407
           P+Q P
Sbjct: 357 PNQVP 361


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 10/89 (11%)

Query: 333 GALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGI-------APPPPPGFGPHMFH 385
           G  PPPP +   +  +    PP+  P     A PPPP +       APPPPP +  H   
Sbjct: 293 GLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSE 352

Query: 386 PMG---PPPPFMRAPGPIHYPSQDPQRMG 411
           P     PPPP  R P     P   P R G
Sbjct: 353 PPSRGKPPPPPSRTPAGPPPPPPPPLRNG 381



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 22/86 (25%), Positives = 30/86 (34%), Gaps = 21/86 (24%)

Query: 321 SGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP----------- 369
           S + +   P      PPPP   +          P+GP +  N + P  P           
Sbjct: 235 SPVNIRTGPSGQSLAPPPPPYRQPPGV------PNGPSSPTNESAPELPQRHNSLHRKTP 288

Query: 370 ----GIAPPPPPGFGPHMFHPMGPPP 391
               G+APPPP    P +     PPP
Sbjct: 289 GPVRGLAPPPPTSASPSLLSNRPPPP 314



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 35/96 (36%)

Query: 336 PPPPAAEEEA----------SANYFN----LPPS----------GPPAVVNIALPPPPGI 371
           PPPP     A           A  +N    LPP+          GPPA        PP +
Sbjct: 179 PPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPA--------PPPV 230

Query: 372 APPPPP---GFGPHMFHPMGPPPPFMRAPGPIHYPS 404
            PPP P     GP       PPPP+ + PG  + PS
Sbjct: 231 KPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPS 266



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 25/90 (27%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFN----LPPSG-------------------PPAVVNI 363
           P PG     PP P     + A  +N    LPP+                    PP+ VNI
Sbjct: 180 PPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNI 239

Query: 364 AL-PPPPGIAPPPPPGFGPHMFHPMGPPPP 392
              P    +APPPPP   P    P GP  P
Sbjct: 240 RTGPSGQSLAPPPPPYRQPPGV-PNGPSSP 268



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 25/66 (37%), Positives = 25/66 (37%), Gaps = 26/66 (39%)

Query: 330 GLPGALPPPPAAEEEASANYFNLPPS-GPPAVVNIALPPPPGIAP--PPPPGFGPHMFHP 386
           G   A PPPP      S      PPS G P       PPPP   P  PPPP         
Sbjct: 335 GARDAPPPPPPYRMHGSE-----PPSRGKP-------PPPPSRTPAGPPPP--------- 373

Query: 387 MGPPPP 392
             PPPP
Sbjct: 374 --PPPP 377


>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
           sapiens]
          Length = 871

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 29/70 (41%), Positives = 33/70 (47%), Gaps = 16/70 (22%)

Query: 335 LPPPPAAEEEASANYFNLPPSGPPAVVNIALPP----PPGIAPPPPPGFGPHMFHPMGPP 390
           +PPP           F  PP  PP    + LPP    PP I PP PPG  P M  PMG P
Sbjct: 2   MPPP-----------FMPPPGIPPPFPPMGLPPMSQRPPAI-PPMPPGILPPMLPPMGAP 49

Query: 391 PPFMRAPGPI 400
           PP  + PG +
Sbjct: 50  PPLTQIPGMV 59



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 12/66 (18%)

Query: 327 PVPGLPGALPP---PPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHM 383
           P PG+P   PP   PP ++          PP+ PP    I  P  P +  PPP    P M
Sbjct: 8   PPPGIPPPFPPMGLPPMSQR---------PPAIPPMPPGILPPMLPPMGAPPPLTQIPGM 58

Query: 384 FHPMGP 389
             PM P
Sbjct: 59  VPPMMP 64


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 32/87 (36%), Positives = 40/87 (45%), Gaps = 19/87 (21%)

Query: 322 GIKLEPVPGLPGA--LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------GIA 372
           G+ +     LPG   +PPPP     A      +PP  PP   +  +PPPP       G+ 
Sbjct: 651 GVGIPSPSSLPGGTAIPPPPPLPGSA-----RIPPPPPPLPGSAGIPPPPPPLPGEAGMP 705

Query: 373 PPPPP-GFGPHMFHPMGPPPPFMRAPG 398
           PPPPP   GP     + PPPPF   PG
Sbjct: 706 PPPPPLPGGP----GIPPPPPFPGGPG 728



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 32/96 (33%), Positives = 40/96 (41%), Gaps = 20/96 (20%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------------GIAP 373
           P+PG  G  PPPP    EA      +PP  PP      +PPPP             G+  
Sbjct: 684 PLPGSAGIPPPPPPLPGEAG-----MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM 738

Query: 374 PPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQR 409
           PPPP FG  +  P  P  PF   P  ++ P    +R
Sbjct: 739 PPPPPFGFGV--PAAPVLPFGLTPKKLYKPEVQLRR 772



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 38/109 (34%), Positives = 45/109 (41%), Gaps = 29/109 (26%)

Query: 322 GIKLEPVPGLPG--ALPPPPAAEEEASANYFNLPPSGP-PAVVNI----------ALPPP 368
           G+ +   P LPG  A+ PPP    +A+     +PP  P P  V I          A+PPP
Sbjct: 615 GVCISSPPSLPGGTAISPPPPLSGDAT-----IPPPPPLPEGVGIPSPSSLPGGTAIPPP 669

Query: 369 PG------IAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMG 411
           P       I PPPPP  G     P  PPPP    PG    P   P   G
Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPP--PPPPL---PGEAGMPPPPPPLPG 713



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 6/107 (5%)

Query: 311 KEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPG 370
           ++ +K+  + S   +   P +P   P PPA      +     PP  P        PPPP 
Sbjct: 547 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 606

Query: 371 IAPPPPPGFGPHMFHPMGP------PPPFMRAPGPIHYPSQDPQRMG 411
             PPP PG       P  P      PPP +     I  P   P+ +G
Sbjct: 607 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 653


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 32/87 (36%), Positives = 40/87 (45%), Gaps = 19/87 (21%)

Query: 322 GIKLEPVPGLPGA--LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------GIA 372
           G+ +     LPG   +PPPP     A      +PP  PP   +  +PPPP       G+ 
Sbjct: 660 GVGIPSPSSLPGGTAIPPPPPLPGSA-----RIPPPPPPLPGSAGIPPPPPPLPGEAGMP 714

Query: 373 PPPPP-GFGPHMFHPMGPPPPFMRAPG 398
           PPPPP   GP     + PPPPF   PG
Sbjct: 715 PPPPPLPGGP----GIPPPPPFPGGPG 737



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 32/96 (33%), Positives = 40/96 (41%), Gaps = 20/96 (20%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-------------GIAP 373
           P+PG  G  PPPP    EA      +PP  PP      +PPPP             G+  
Sbjct: 693 PLPGSAGIPPPPPPLPGEAG-----MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM 747

Query: 374 PPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQR 409
           PPPP FG  +  P  P  PF   P  ++ P    +R
Sbjct: 748 PPPPPFGFGV--PAAPVLPFGLTPKKLYKPEVQLRR 781



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 38/109 (34%), Positives = 45/109 (41%), Gaps = 29/109 (26%)

Query: 322 GIKLEPVPGLPG--ALPPPPAAEEEASANYFNLPPSGP-PAVVNI----------ALPPP 368
           G+ +   P LPG  A+ PPP    +A+     +PP  P P  V I          A+PPP
Sbjct: 624 GVCISSPPSLPGGTAISPPPPLSGDAT-----IPPPPPLPEGVGIPSPSSLPGGTAIPPP 678

Query: 369 PG------IAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMG 411
           P       I PPPPP  G     P  PPPP    PG    P   P   G
Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPP--PPPPL---PGEAGMPPPPPPLPG 722



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 6/107 (5%)

Query: 311 KEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPG 370
           ++ +K+  + S   +   P +P   P PPA      +     PP  P        PPPP 
Sbjct: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP 615

Query: 371 IAPPPPPGFGPHMFHPMGP------PPPFMRAPGPIHYPSQDPQRMG 411
             PPP PG       P  P      PPP +     I  P   P+ +G
Sbjct: 616 PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 662


>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 25/52 (48%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 353 PPSGPPAVVNIALPP----PPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPI 400
           PP  PP    + LPP    PP I PP PPG  P M  PMG PPP  + PG +
Sbjct: 3   PPGIPPPFPPMGLPPMSQRPPAI-PPMPPGILPPMLPPMGAPPPLTQIPGMV 53



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 12/66 (18%)

Query: 327 PVPGLPGALPP---PPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHM 383
           P PG+P   PP   PP ++          PP+ PP    I  P  P +  PPP    P M
Sbjct: 2   PPPGIPPPFPPMGLPPMSQR---------PPAIPPMPPGILPPMLPPMGAPPPLTQIPGM 52

Query: 384 FHPMGP 389
             PM P
Sbjct: 53  VPPMMP 58


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 29/67 (43%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNL-PPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFH 385
           P+PGLP     PP+A  +A     +  PP  PP   +  LPPPP   PPPP   GP    
Sbjct: 547 PLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGD--LPPPPPPPPPPPGTDGPVPPP 604

Query: 386 PMGPPPP 392
           P  PPPP
Sbjct: 605 PPPPPPP 611



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/55 (45%), Positives = 27/55 (49%), Gaps = 15/55 (27%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGP 381
           P P LPG LPPPP             PP  PP   +  +PPPP   PPPPP  GP
Sbjct: 576 PAPPLPGDLPPPP-------------PPPPPPPGTDGPVPPPP--PPPPPPPGGP 615



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 32/83 (38%), Positives = 34/83 (40%), Gaps = 10/83 (12%)

Query: 326 EPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGI-APPPPPGFGPHMF 384
           EP PG   A PPPP      S      PPS PP       PP PG   PPP P     + 
Sbjct: 535 EPAPG--AAPPPPPPLPGLPSPQ--EAPPSAPPQA-----PPLPGSPEPPPAPPLPGDLP 585

Query: 385 HPMGPPPPFMRAPGPIHYPSQDP 407
            P  PPPP     GP+  P   P
Sbjct: 586 PPPPPPPPPPGTDGPVPPPPPPP 608



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/62 (41%), Positives = 28/62 (45%), Gaps = 11/62 (17%)

Query: 329 PGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMG 388
           P LPG+  PPPA          +LPP  PP       PPPPG   P PP   P    P G
Sbjct: 566 PPLPGSPEPPPAPPLPG-----DLPPPPPPP------PPPPGTDGPVPPPPPPPPPPPGG 614

Query: 389 PP 390
           PP
Sbjct: 615 PP 616



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 6/71 (8%)

Query: 335 LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGF----GPHMFHPMGPP 390
           LP   A      A    +P   P   +  A  P PG APPPPP       P    P  PP
Sbjct: 504 LPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPP 563

Query: 391 --PPFMRAPGP 399
             PP   +P P
Sbjct: 564 QAPPLPGSPEP 574


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 30/74 (40%), Positives = 33/74 (44%), Gaps = 17/74 (22%)

Query: 321 SGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAP--PPPPG 378
           +G  L P P  P  LPPP +A           PP  PP + N   PP PG  P  PPPPG
Sbjct: 676 AGPPLPPPPPPPPPLPPPSSAGPP--------PPPPPPPLPNSPAPPNPGGPPPAPPPPG 727

Query: 379 FGPHMFHPMGPPPP 392
             P       PPPP
Sbjct: 728 LAP-------PPPP 734



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 38/86 (44%), Gaps = 14/86 (16%)

Query: 325 LEPVPGLPG----ALPPPPAA-----EEEASANYFNLPPSGPPAVVNIALPPPPGIAP-- 373
           L+P+ G+      ALPPPPA+        +     +  P  PP      LPPPP   P  
Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690

Query: 374 PPPPGFGPHMFHPMGPPPPFMRAPGP 399
           PPP   GP    P  PPPP   +P P
Sbjct: 691 PPPSSAGP---PPPPPPPPLPNSPAP 713



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 32/95 (33%), Positives = 40/95 (42%), Gaps = 8/95 (8%)

Query: 327 PVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVV--NIALPPPPGIAPPPPPGFGPHMF 384
           P+P   G+L P P     ++      PP  PP +   + A PPPP   PPPP    P   
Sbjct: 657 PLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPP--PPPPPLPNSPAPP 714

Query: 385 HPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSS 419
           +P GPPP    AP P       P  +    G  SS
Sbjct: 715 NPGGPPP----APPPPGLAPPPPPGLFFGLGSSSS 745



 Score = 36.2 bits (82), Expect = 0.057
 Identities = 22/56 (39%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 353 PPSGPPAVVNIALPPPPGIAPPPPP-GFGPHMFHPMGPPPPFMRAPGPIHYPSQDP 407
           P  G  +    ALPPPP   PPPPP   G     P  P PP    P P+  P   P
Sbjct: 633 PMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGP-PLPPPPPPP 687


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 36/92 (39%), Positives = 41/92 (44%), Gaps = 14/92 (15%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPP-----GIA 372
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP     GI 
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185

Query: 373  PPPP-PGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP PG G     P  PP P    P P   P
Sbjct: 1186 PPPPLPGVGI----PPPPPLPGAGIPPPPPLP 1213



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 36/92 (39%), Positives = 41/92 (44%), Gaps = 14/92 (15%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPP-----GIA 372
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP     GI 
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1108

Query: 373  PPPP-PGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP PG G     P  PP P    P P   P
Sbjct: 1109 PPPPLPGAGI----PPPPPLPGAGIPPPPPLP 1136



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 15/93 (16%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI----AP 373
            G  + P P LPGA +PPPP            LP +G   PP +  + +PPPP +     P
Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP 1119

Query: 374  PPPPGFGPHMFHP-------MGPPPPFMRAPGP 399
            PPPP  G  +  P       + PPPP  R   P
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP 1152



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G+ + P P LPGA +PPPP            LP +G   PP +  + +PPPP +  A  P
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP 1163

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P +  P P   P
Sbjct: 1164 PPPPLPGAGI--PPPPPLPGVGIPPPPPLP 1191



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 23/93 (24%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGI--A--PPPP 376
            G  + P P LPGA +PPPP            +PP  PP +  + +PPPP +  A  PPPP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPG------VGIPP--PPPLPGVGIPPPPPLPGAGIPPPP 1210

Query: 377  P----GFGPHMFHPMG------PPPPFMRAPGP 399
            P    G  P    P+       PPPP +   GP
Sbjct: 1211 PLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/85 (40%), Positives = 39/85 (45%), Gaps = 11/85 (12%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIA--PPPPPG 378
            G  + P+P LPGA +PPPP     A      +PP  P     I LPPP   A  PPPPP 
Sbjct: 928  GAGILPLPPLPGAGIPPPPPLPGAA------IPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981

Query: 379  FGPHMFHPMGPPPPFMRAPGPIHYP 403
             G  +  P  PP P    P P   P
Sbjct: 982  PGAGI--PPPPPLPGAGIPPPPPLP 1004



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP +  A  P
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1086

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P +  P P   P
Sbjct: 1087 PPPPLPGAGI--PPPPPLPGVGIPPPPPLP 1114



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 32/88 (36%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--APPP 375
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP +  A  P
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097

Query: 376  PPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PP   P +  P  PP P    P P   P
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLP 1125



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP +  A  P
Sbjct: 972  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P    P P   P
Sbjct: 1032 PPPPLPGAGI--PPPPPLPGAGIPPPPPLP 1059



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP +  A  P
Sbjct: 983  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1042

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P    P P   P
Sbjct: 1043 PPPPLPGAGI--PPPPPLPGAGIPPPPPLP 1070



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G  + P P LPGA +PPPP            LP +G   PP +    +PPPP +  A  P
Sbjct: 939  GAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P    P P   P
Sbjct: 999  PPPPLPGAGI--PPPPPLPGAGIPPPPPLP 1026



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 1/69 (1%)

Query: 336 PPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIA-PPPPPGFGPHMFHPMGPPPPFM 394
           PP P  E  +S     + P  PP +  + +P  P  A P PPP  G  M  P  PP P  
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918

Query: 395 RAPGPIHYP 403
             P P   P
Sbjct: 919 GIPPPPPLP 927



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 20/78 (25%)

Query: 327 PVPGLPGA-LPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFH 385
           P P LPGA +PPPP            LP +G      + LPP PG   PPPP   P    
Sbjct: 911 PPPPLPGAGIPPPPP-----------LPGAGI-----LPLPPLPGAGIPPPP---PLPGA 951

Query: 386 PMGPPPPFMRAPGPIHYP 403
            + PPPP   A  P+  P
Sbjct: 952 AIPPPPPLPGAGIPLPPP 969



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 10/90 (11%)

Query: 322  GIKLEPVPGLPGA-LPPPPAAEEEASANYFNLPPSG---PPAVVNIALPPPPGI--A--P 373
            G  + P P LPGA +P PP            LP +G   PP +    +PPPP +  A  P
Sbjct: 950  GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1009

Query: 374  PPPPGFGPHMFHPMGPPPPFMRAPGPIHYP 403
            PPPP  G  +  P  PP P    P P   P
Sbjct: 1010 PPPPLPGAGI--PPPPPLPGAGIPPPPPLP 1037



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 31/79 (39%), Positives = 36/79 (45%), Gaps = 19/79 (24%)

Query: 328 VPGLPG-ALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPP-----GIAP-PPPPGFG 380
           VP LP  A+P PP  +         LPP  PP +    +PPPP     GI P PP PG G
Sbjct: 888 VPTLPSTAIPQPPPLQGTEM-----LPPP-PPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941

Query: 381 PHMFHPMGPPPPFMRAPGP 399
                 + PPPP   A  P
Sbjct: 942 ------IPPPPPLPGAAIP 954



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 8/95 (8%)

Query: 311 KEKEKDGTTDSGI-KLEPVPGLPGALPPPPAAEEEASANYFN-LPPSGPPAVVNIAL--- 365
           K  +   T + G+  L PV GLPG  P PP AE      + + +     P  +++ L   
Sbjct: 742 KSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH 801

Query: 366 PPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPI 400
            P   I+ PPPP   P +    G   P  + P  I
Sbjct: 802 QPTQSISQPPPP---PSLLWSAGQGQPGSQPPHSI 833



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 38/139 (27%), Positives = 52/139 (37%), Gaps = 24/139 (17%)

Query: 291 LIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEE------- 343
           LIV+ RR++V+    Q  +   +     +   +      G PG+ PP   + E       
Sbjct: 787 LIVSPRRISVQLDSHQPTQSISQPPPPPS---LLWSAGQGQPGSQPPHSISTEFQTSHEH 843

Query: 344 ---EASANYFNLPPSGP-PAVVNIALPPPPGIAPPPPPGFGPHMFHPMGP------PPPF 393
               A  N  N+P   P P   + +  P  G+ PPPPP   P M  P  P      PPP 
Sbjct: 844 SVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPL-PGMTVPTLPSTAIPQPPPL 902

Query: 394 MRAPGPIHYPSQDPQRMGA 412
               G    P   P   GA
Sbjct: 903 Q---GTEMLPPPPPPLPGA 918


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,156,689
Number of Sequences: 37866
Number of extensions: 1518829
Number of successful extensions: 19658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 420
Number of HSP's successfully gapped in prelim test: 992
Number of HSP's that attempted gapping in prelim test: 8863
Number of HSP's gapped (non-prelim): 6146
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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