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Search of human proteins with 88758580
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88758580 cyclin L2 isoform A [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88758580 cyclin L2 isoform A [Homo sapiens] 1035 0.0
gi|9945320 cyclin L1 [Homo sapiens] 583 e-166
gi|221554516 cyclin L2 isoform C [Homo sapiens] 437 e-122
gi|221554518 cyclin L2 isoform D [Homo sapiens] 436 e-122
gi|88758578 cyclin L2 isoform B [Homo sapiens] 436 e-122
gi|150417989 cyclin K isoform 1 [Homo sapiens] 115 7e-26
gi|38176158 cyclin K isoform 2 [Homo sapiens] 115 1e-25
gi|17978469 cyclin T2 isoform b [Homo sapiens] 101 1e-21
gi|4502629 cyclin T2 isoform a [Homo sapiens] 101 1e-21
gi|17978466 cyclin T1 [Homo sapiens] 99 1e-20
gi|196049382 family with sequence similarity 58, member A isofor... 95 1e-19
gi|196049384 family with sequence similarity 58, member A isofor... 93 5e-19
gi|157502165 family with sequence similarity 58 member B [Homo s... 84 4e-16
gi|61676091 cyclin C isoform a [Homo sapiens] 80 5e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 78 2e-14
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 72 1e-12
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 71 2e-12
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 69 8e-12
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 68 2e-11
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 67 3e-11
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 67 5e-11
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 67 5e-11
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 66 7e-11
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 66 9e-11
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 66 9e-11
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 66 9e-11
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 65 1e-10
gi|46309849 hypothetical protein LOC57035 [Homo sapiens] 65 1e-10
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 65 2e-10
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 65 2e-10
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 1035 bits (2677), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR
Sbjct: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
Query: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM
Sbjct: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
Query: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE
Sbjct: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
Query: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESI 240
RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESI
Sbjct: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESI 240
Query: 241 ACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEK 300
ACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEK
Sbjct: 241 ACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEK 300
Query: 301 RKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLE 360
RKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLE
Sbjct: 301 RKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLE 360
Query: 361 GAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSR 420
GAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSR
Sbjct: 361 GAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSR 420
Query: 421 SRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNP 480
SRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNP
Sbjct: 421 SRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNP 480
Query: 481 GKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
GKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR
Sbjct: 481 GKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 583 bits (1502), Expect = e-166
Identities = 315/532 (59%), Positives = 392/532 (73%), Gaps = 23/532 (4%)
Query: 5 AAAAGAAGSAAPAAAAGAPGSGGAPSGSQ--------GVLIGDRLYSGVLITLENCLLPD 56
A+ + +AA AA++ AP +GG+ SG+ G+LIGDRLYS V +T+++ L+P+
Sbjct: 2 ASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPE 61
Query: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
++L TPSM GLD +ETDLR++GCELIQAAGILLRLPQVAMATGQVLF RFFY+KSFV
Sbjct: 62 ERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFV 121
Query: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
KHS E V+MAC++LASKIEEAPRRIRDVINVFH LRQLR K+ P PL+LDQ+Y+N KNQ+
Sbjct: 122 KHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQV 181
Query: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQ 236
IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQ LVQT+WNYMNDSLRT+VFVRFQ
Sbjct: 182 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQ 241
Query: 237 PESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEG 296
PE+IACACIYLAAR L+IPLP RPHWFLLFG TEEEIQEIC++ L+LY RKK + LE
Sbjct: 242 PETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEK 301
Query: 297 EVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLS--VKN 354
EVEKRK A++EAK +A+GL P GT L GFSPA K SP+E K + SP+S VK
Sbjct: 302 EVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASK-PSSPREVKAEEKSPISINVKT 360
Query: 355 TKRRLEGAKKAKADSPVNGLPKG--RESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTS 412
K+ E ++A + SP NG+ K R SRS SR +S +RS SRS +P+R ++ S S
Sbjct: 361 VKKEPEDRQQA-SKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRS 419
Query: 413 G--GSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSR 470
G S+S+SRSRS S+SP R +P+ ++ D K + R +S SRS+
Sbjct: 420 GTYSSRSRSRSRSHSESPRRHHNHGSPH----LKAKHTRDDLKSSNRHGHKRKKSRSRSQ 475
Query: 471 SRSRERADNPGKYKKKSHYYRDQRRERSRSYERT--GRRYERDHPGHSRHRR 520
S+SR+ +D K++ + ++RD RRERSRS+ER+ + + GH RHRR
Sbjct: 476 SKSRDHSDAAKKHRHERGHHRD-RRERSRSFERSHKSKHHGGSRSGHGRHRR 526
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 437 bits (1124), Expect = e-122
Identities = 222/227 (97%), Positives = 222/227 (97%)
Query: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR
Sbjct: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
Query: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM
Sbjct: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
Query: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE
Sbjct: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
Query: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSL 227
RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW D L
Sbjct: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWVASEDPL 227
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 436 bits (1121), Expect = e-122
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR
Sbjct: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
Query: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM
Sbjct: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
Query: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE
Sbjct: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
Query: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW
Sbjct: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 436 bits (1121), Expect = e-122
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR
Sbjct: 1 MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLR 60
Query: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM
Sbjct: 61 FTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSM 120
Query: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE
Sbjct: 121 EHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAE 180
Query: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW
Sbjct: 181 RRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW 220
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 115 bits (289), Expect = 7e-26
Identities = 96/357 (26%), Positives = 164/357 (45%), Gaps = 43/357 (12%)
Query: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
Query: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
Query: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSWNYMNDSLRTDVFVRFQ 236
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W ++NDSL T + ++++
Sbjct: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWE 202
Query: 237 PESIACACIYLAARTLEIPL------PNRPHWFLLF--GATEEEIQEICLKILQLYARKK 288
PE IA A +YLA R + + P W+ F + +++IC +IL LY++ K
Sbjct: 203 PEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK 262
Query: 289 VDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPS 348
+ H H ++ Q L P +P V+ + + S+PS
Sbjct: 263 QQMPH------HTPHQLQ----QPPSLQP------------TPQVPQVQQSQPSQSSEPS 300
Query: 349 PLSVKNTK---RRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPK 402
K+ + ++ + A++ K SP P+ + +E++ + P PK
Sbjct: 301 QPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPK 357
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 115 bits (288), Expect = 1e-25
Identities = 77/245 (31%), Positives = 125/245 (51%), Gaps = 18/245 (7%)
Query: 59 LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKH 118
L TPS GLD TE R G I G L L +ATG + F RF+ SF +
Sbjct: 31 LAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQF 90
Query: 119 SMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIK 178
C+ LA K+EE P++ +D+I L L D + Q + K +++
Sbjct: 91 PRYVTGACCLFLAGKVEETPKKCKDIIKTARSL--LND------VQFGQFGDDPKEEVMV 142
Query: 179 AERRVLKELGFCVHVKHPHKIIVMYLQVLECERN--QHLVQTSWNYMNDSLRTDVFVRFQ 236
ER +L+ + F + V+HP++ ++ Y + L+ ++N Q LVQ +W ++NDSL T + ++++
Sbjct: 143 LERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWE 202
Query: 237 PESIACACIYLAARTLEIPL------PNRPHWFLLF--GATEEEIQEICLKILQLYARKK 288
PE IA A +YLA R + + P W+ F + +++IC +IL LY++ K
Sbjct: 203 PEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK 262
Query: 289 VDLTH 293
+ H
Sbjct: 263 QQMPH 267
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 101 bits (252), Expect = 1e-21
Identities = 97/374 (25%), Positives = 162/374 (43%), Gaps = 34/374 (9%)
Query: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
Query: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
Query: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF- 232
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ +SL F
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
Query: 233 VRFQPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE-----EEIQEICLKILQLY 284
++++P IAC CI+LA + EIP+ + HW+ T +E+ L+IL+
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
Query: 285 ARKKVDLTHLEGEVEKRKHAIEEAKAQARGL---LPGGTQVLDGTSGFSPAPKLVESPKE 341
+ + + RK ++ ++ L L + ++D +G P + P
Sbjct: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSF-QKPST 306
Query: 342 GKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSY-----SRSPS 396
P PL+ N + + ++ L G S S S Q + S
Sbjct: 307 SAFPAPVPLNSGNI-----SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTE 361
Query: 397 RSASPKRRKSDSGS 410
+ S K+ S SGS
Sbjct: 362 QLYSQKQETSLSGS 375
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 13/141 (9%)
Query: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSR-SRSREQSYSRSPS---RSASPKRRKS 406
S + K +++ + + S G K + S SR ++ + PS ++S K S
Sbjct: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
Query: 407 DSGSTSGGSKSQSRSRSRSDSPPR--QAPRSAPYKG--SEIRGSRKSKDCKYPQKPHKSR 462
SGS+SGGSK S PP ++P G S SRK H S+
Sbjct: 579 HSGSSSGGSK-----HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
Query: 463 SRSSSRSRSRSRERADNPGKY 483
SS+S S + + +Y
Sbjct: 634 MSKSSKSSGSSSSSSSSVKQY 654
>gi|4502629 cyclin T2 isoform a [Homo sapiens]
Length = 663
Score = 101 bits (252), Expect = 1e-21
Identities = 97/374 (25%), Positives = 162/374 (43%), Gaps = 34/374 (9%)
Query: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
++L TPS G++ D E R LIQ G L + Q+ + T V RF+ SF
Sbjct: 16 EQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75
Query: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLD---QDYVNLK 173
K + +S + LA+K+EE R++ VI V H P+ LLD Y+
Sbjct: 76 KFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLH------PLEPLLDTKCDAYLQQT 129
Query: 174 NQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF- 232
+++ E +L+ LGF + ++HPH +V Q++ ++ L QTS+ +SL F
Sbjct: 130 QELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFC 187
Query: 233 VRFQPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE-----EEIQEICLKILQLY 284
++++P IAC CI+LA + EIP+ + HW+ T +E+ L+IL+
Sbjct: 188 LQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKT 247
Query: 285 ARKKVDLTHLEGEVEKRKHAIEEAKAQARGL---LPGGTQVLDGTSGFSPAPKLVESPKE 341
+ + + RK ++ ++ L L + ++D +G P + P
Sbjct: 248 PNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSF-QKPST 306
Query: 342 GKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSY-----SRSPS 396
P PL+ N + + ++ L G S S S Q + S
Sbjct: 307 SAFPAPVPLNSGNI-----SVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTE 361
Query: 397 RSASPKRRKSDSGS 410
+ S K+ S SGS
Sbjct: 362 QLYSQKQETSLSGS 375
Score = 33.9 bits (76), Expect = 0.37
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSR-SRSREQSYSRSPS---RSASPKRRKS 406
S + K +++ + + S G K + S SR ++ + PS ++S K S
Sbjct: 519 SKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHS 578
Query: 407 DSGSTSGGSKSQSRSRSRSDSPPR--QAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSR 464
SGS+SGGSK S PP ++P G S K H S+
Sbjct: 579 HSGSSSGGSK-----HSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSK 633
Query: 465 SSSRSRS 471
S S+S
Sbjct: 634 MSKSSKS 640
>gi|17978466 cyclin T1 [Homo sapiens]
Length = 726
Score = 98.6 bits (244), Expect = 1e-20
Identities = 68/233 (29%), Positives = 117/233 (50%), Gaps = 11/233 (4%)
Query: 57 DKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFV 116
++L +PS G+D D E R L+Q G L + Q+ + T V RF+ +SF
Sbjct: 17 EQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFT 76
Query: 117 KHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQI 176
+ V+ A + LA+K+EE P+++ VI V H ++ +P + Y+ +
Sbjct: 77 QFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLH---PQESLPDTRSEAYLQQVQDL 133
Query: 177 IKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVF-VRF 235
+ E +L+ LGF + + HPH +V Q++ ++ L QTS+ +SL F +++
Sbjct: 134 VILESIILQTLGFELTIDHPHTHVVKCTQLVRASKD--LAQTSYFMATNSLHLTTFSLQY 191
Query: 236 QPESIACACIYLAAR--TLEIPL-PNRPHWFLLFGATE--EEIQEICLKILQL 283
P +AC CI+LA + EIP+ + HW+ AT E + E+ + LQ+
Sbjct: 192 TPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQI 244
>gi|196049382 family with sequence similarity 58, member A isoform 1
[Homo sapiens]
Length = 248
Score = 95.1 bits (235), Expect = 1e-19
Identities = 64/213 (30%), Positives = 110/213 (51%), Gaps = 18/213 (8%)
Query: 85 IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144
I AG+ L + + +AT ++ +FF + + ++M+ ++LA K+EE R RD+
Sbjct: 34 IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93
Query: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204
INV +R + PL LD + L++ I++ E +L+ L F V +HPHK ++ YL
Sbjct: 94 INVSNRYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYL 149
Query: 205 QVLECERNQHLVQ------TSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLP- 257
L+ N+H Q T+W + DS + +RFQ + IA A +YLA + + +P
Sbjct: 150 VSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPA 209
Query: 258 ----NRPHWFLLFG--ATEEEIQEICLKILQLY 284
+P W+ +F T+ I I ++Q+Y
Sbjct: 210 EVEAEKP-WWQVFNDDLTKPIIDNIVSDLIQIY 241
>gi|196049384 family with sequence similarity 58, member A isoform 2
[Homo sapiens]
Length = 228
Score = 93.2 bits (230), Expect = 5e-19
Identities = 60/197 (30%), Positives = 101/197 (51%), Gaps = 15/197 (7%)
Query: 85 IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144
I AG+ L + + +AT ++ +FF + + ++M+ ++LA K+EE R RD+
Sbjct: 34 IMEAGVKLGMRSIPIATACTIYHKFFCETNLDAYDPYLIAMSSIYLAGKVEEQHLRTRDI 93
Query: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204
INV +R + PL LD + L++ I++ E +L+ L F V +HPHK ++ YL
Sbjct: 94 INVSNRYFNPSGE----PLELDSRFWELRDSIVQCELLMLRVLRFQVSFQHPHKYLLHYL 149
Query: 205 QVLECERNQHLVQ------TSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLP- 257
L+ N+H Q T+W + DS + +RFQ + IA A +YLA + + +P
Sbjct: 150 VSLQNWLNRHSWQRTPVAVTAWALLRDSYHGALCLRFQAQHIAVAVLYLALQVYGVEVPA 209
Query: 258 ----NRPHWFLLFGATE 270
+P W + TE
Sbjct: 210 EVEAEKPWWQIYTMDTE 226
>gi|157502165 family with sequence similarity 58 member B [Homo
sapiens]
Length = 252
Score = 83.6 bits (205), Expect = 4e-16
Identities = 60/212 (28%), Positives = 101/212 (47%), Gaps = 16/212 (7%)
Query: 85 IQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDV 144
I AG+ L + + +AT ++ +FF ++M+ ++LA K+EE P D+
Sbjct: 38 IMEAGVKLGMQSIPIATACTIYPKFFCETILDAFDPYLIAMSSIYLAGKVEEQPLWAHDI 97
Query: 145 INVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYL 204
I+V +R + PL LD L++ I++ E +L+ L F V +HPHK ++ YL
Sbjct: 98 ISVSNRYFNPSSE----PLGLDSRLWELRDSIVQRELLMLRVLRFQVSFQHPHKYLLYYL 153
Query: 205 QVLECERNQHLVQ------TSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPN 258
L+ N H Q T+W + DS + +RFQ + IA +YLA + + +P
Sbjct: 154 VSLKNWLNCHSWQRTPVAVTAWALLRDSYHGGLCLRFQAQHIAVVVLYLALQVYGVEVPA 213
Query: 259 RPH----WFLLFG--ATEEEIQEICLKILQLY 284
W+ F T+ I I ++Q+Y
Sbjct: 214 EVEAEKLWWQAFSDDLTKPIIDTIVSDLIQIY 245
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 80.1 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 105/214 (49%), Gaps = 13/214 (6%)
Query: 77 LRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMA--CVHLASKI 134
L++ +IQA G L+L Q +AT V F+RF+ S S++ V MA CV LASK+
Sbjct: 40 LQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSL--KSIDPVLMAPTCVFLASKV 97
Query: 135 EEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVK 194
EE V N K +++ N I++ E +L+ + C+ V
Sbjct: 98 EE----FGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVY 153
Query: 195 HPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEI 254
HP++ ++ Y+Q + + L+ +W +ND+ RTD+ + + P IA AC+++A +
Sbjct: 154 HPYRPLLQYVQ--DMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVAC---VV 208
Query: 255 PLPNRPHWFLLFGATEEEIQEICLKILQLYARKK 288
+ WF E+I EI IL+LY + K
Sbjct: 209 QQKDARQWFAELSVDMEKILEIIRVILKLYEQWK 242
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 77.8 bits (190), Expect = 2e-14
Identities = 68/201 (33%), Positives = 95/201 (47%), Gaps = 47/201 (23%)
Query: 364 KAKADSPVNGLPKGRE---SRSRSRSREQSYSRSPSR------SASPKRRKSDSGSTSGG 414
K K+ + +GR SR+ S+ R S+SRS S+ S+SP++ +SG + G
Sbjct: 337 KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK---ESGRSQSG 393
Query: 415 SKSQSRSRSRSDSPPRQAPRS---APYKG---SEIRGSRKSKDCKYPQKPHKSRSRSSSR 468
S ++ R SRS SP + RS +PYK S R K++DC + P+K+R RS SR
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
Query: 469 S--------------RSRSRERADNPGKYKKKSHY-----YRDQRRERSRSYERTGRR-- 507
S ++R R R+ +P K + S RD RR RS S ER R+
Sbjct: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
Query: 508 ---YERDH-----PGHSRHRR 520
ERDH P R RR
Sbjct: 514 SSSKERDHRRSRSPSKERQRR 534
Score = 69.3 bits (168), Expect = 8e-12
Identities = 63/203 (31%), Positives = 97/203 (47%), Gaps = 25/203 (12%)
Query: 337 ESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSP- 395
ES + GS ++ + ++++ SP + R SRS +++R+ S SRSP
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR-SRSPNKARDCSRSRSPY 444
Query: 396 -----SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRS---APYKGSEIRGSR 447
SRS SP + + S S S +++R RSRS SP ++ S +P K + R SR
Sbjct: 445 KARDRSRSRSPNKARDHSRSRS---PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
Query: 448 ---KSKDCKYPQKPHKSRS--RSSSRSRSRSRERADNPGKYKKKSH-----YYRDQRRER 497
K + C+ + K R RS S S+ R R ++ +P K + +S R+ R+ R
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
Query: 498 SRSYERTGRRYERDHPGHSRHRR 520
S S ER RR+ P R RR
Sbjct: 562 SPSKERDRRRWR--SPSKERERR 582
Score = 65.1 bits (157), Expect = 1e-10
Identities = 56/164 (34%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 365 AKADSPVNGLPKGRESRSRSRSREQSYSRSP------SRSASPKRRKSDSGSTSGGSKSQ 418
+++ SP + R SRS +++R+ S SRSP SRS SP + + D SK +
Sbjct: 438 SRSRSPYKARDRSR-SRSPNKARDHSRSRSPNKARDRSRSRSPSKER-DHSQLGSPSKER 495
Query: 419 SRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERAD 478
RSRS S RQ +S S+ R R+S+ ++ +SRS + R RS+SR ++
Sbjct: 496 DHRRSRSPSKERQCRQSR--SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
Query: 479 NPGKYKKKS-HYYRDQRRERSRSYERTGR--RYERDHPGHSRHR 519
+ +S RD+RR RS S ER R R + HSR R
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR 597
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/198 (30%), Positives = 90/198 (45%), Gaps = 32/198 (16%)
Query: 348 SPLSVKNTKRRLEGAKKAKADSPVNGLPKGRE-SRSRSRSREQSYSR--SPS------RS 398
SP ++ + R KA+ S K R+ SRSRS S+E+ +S+ SPS RS
Sbjct: 442 SPYKARD-RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS 500
Query: 399 ASPKRRKSDSGSTSGG---------SKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKS 449
SP + + S S S S+ R R +S SP ++ RS SE R R+S
Sbjct: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQS 560
Query: 450 K------DCKYPQKPHKSRSRSSSRSRSRSRE--RADNPGKYKKKSHYYRDQRRERSRSY 501
+ D + + P K R R SRS S R+ R+ +P K+S Y R + + +++
Sbjct: 561 RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP---NKQSGYSRPRASSKEKAH 617
Query: 502 ERTGRRYERDHPGHSRHR 519
R+ R HS+ R
Sbjct: 618 SRS--RTPSKEGNHSQSR 633
Score = 52.8 bits (125), Expect = 8e-07
Identities = 51/183 (27%), Positives = 74/183 (40%), Gaps = 15/183 (8%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRS----REQSYSR 393
SP + + + S S K R + + + P RS+SRS RE SR
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
Query: 394 SPSRSASPKRRKSDSGSTS---GGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSK 450
SPS+ +R +S S S S+ R SRS SP +Q+ S P R S K K
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP------RASSKEK 615
Query: 451 DCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYER 510
+ P S+ + S+SR+ S+E + + + R R S S RT +
Sbjct: 616 AHSRSRTP--SKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673
Query: 511 DHP 513
P
Sbjct: 674 HSP 676
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 18/160 (11%)
Query: 377 GRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPR-- 434
G + R+ SR R S+ R+ SR+ S + RK S+S+S S+ +S + R R
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARS-RTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGR 351
Query: 435 --------SAPYKGSEIRGSRKSKDCKYPQKPHK--SRSRSSSRSRSRSRERADNPGKYK 484
S S R S K +D + P K RS+S S ++ R R+ +P K +
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411
Query: 485 KKS-----HYYRDQRRERSRSYERTGRRYERDHPGHSRHR 519
+S + RD+ R RS + R R + R R
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451
Score = 49.3 bits (116), Expect = 9e-06
Identities = 58/188 (30%), Positives = 80/188 (42%), Gaps = 45/188 (23%)
Query: 323 LDGTSGFSPAPKLVES-PKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESR 381
L T +P LV + P + S SP S K+TK K+A ++ P
Sbjct: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKST--STKRAPSNRP----------- 78
Query: 382 SRSRSREQSYSRSPSRSASPKRRKSDS----------------GSTSG--GSKSQSRSRS 423
SRSR +S +R+PSR ++ R S G T G GS+S RS S
Sbjct: 79 -SSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPS 137
Query: 424 RSDSPPRQAPRSA-PYKGSEIRGSRKSKDCKYPQKPHK-SRSRSSSRSRSRSRERADN-P 480
R+ +P R A P S +R P K SR +S R R+ +RER+D+ P
Sbjct: 138 RASTPGRIRTHGARPGMASRVR---------TPTSQQKGSRGKSYGRPRTSNRERSDSQP 188
Query: 481 GKYKKKSH 488
KKS+
Sbjct: 189 RNLSKKSY 196
Score = 49.3 bits (116), Expect = 9e-06
Identities = 43/170 (25%), Positives = 70/170 (41%), Gaps = 1/170 (0%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSR 397
SP + + + S K + R + + D + P R +SRS + RS SR
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 398 SASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQK 457
S S +R S S S + + R RS S R+ RS+ + R +K Y +
Sbjct: 550 SPSEEREHRQSRSPSK-ERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
Query: 458 PHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRR 507
S+ ++ SRSR+ S+E + + K RS ++R+ R
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTR 658
Score = 47.4 bits (111), Expect = 3e-05
Identities = 65/280 (23%), Positives = 104/280 (37%), Gaps = 62/280 (22%)
Query: 292 THLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLS 351
TH G R+ + ++ +R PG + G A ++ + KGS+
Sbjct: 117 THSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGM--ASRVRTPTSQQKGSRGKSYG 174
Query: 352 VKNTKRRLEGAKKAKADSPVNGLPKGRES--RSRSRSREQSYSRSPSRSASPKRRKSDSG 409
T R + + S + P G RS + S ++ + + P + KSD+
Sbjct: 175 RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP 234
Query: 410 STSGGSKSQSR------SRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRS 463
S S K +S SR +S SP + R Y + R PQ +SRS
Sbjct: 235 SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSR--------PQSHSQSRS 286
Query: 464 RSSSRS----------------------RSRSRE------------RADNPGKYKKKS-- 487
SRS RSR+R+ R+ + GK + +S
Sbjct: 287 PRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT 346
Query: 488 -------HYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
++ R+ +ERS S+ R+ + ERDH G S R+
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSK-ERDHRGSSSPRK 385
Score = 46.2 bits (108), Expect = 7e-05
Identities = 65/246 (26%), Positives = 94/246 (38%), Gaps = 64/246 (26%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEG--------AKKAKADSPVNGLPKGRESRSRSRSREQ 389
S K ++PS S +K R +K +KA +G SR R+ R
Sbjct: 69 STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG 128
Query: 390 SYS--RSPSRSASPKRRKSDSG------------STSGGSKSQS------RSRSRSDSPP 429
S S RSPSR+++P R ++ S GS+ +S +R RSDS P
Sbjct: 129 SRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQP 188
Query: 430 RQAPR--------SAPYKGSEIRGSRKSKDCKYPQK-PHKSRSRSSSRSRSR-------- 472
R + S + SE+ + + C+ P P K +S + S S SR
Sbjct: 189 RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQM 248
Query: 473 ---SRERADNPGKYKKKSHYY---------------RDQRRERSRSYERTGRRYERDHPG 514
SRE++ +P + + Y R RR RS S +RT R R H
Sbjct: 249 IIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV-RSHSW 307
Query: 515 HSRHRR 520
H R
Sbjct: 308 KRNHSR 313
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 8/133 (6%)
Query: 338 SPKEGKGSKPS--PLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSP 395
SP E + + S P ++ +R +K+ + + + SRSRS +++ YSR P
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSR-P 608
Query: 396 SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQ-APRSAPYKGSEIRGSRKSKDCKY 454
S+ K + G+ SQSR+ S+ P + PRS +K S R S S++
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN--- 665
Query: 455 PQKPHKSRSRSSS 467
+ P K+ S S S
Sbjct: 666 -RTPSKTSSHSPS 677
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 72.0 bits (175), Expect = 1e-12
Identities = 72/279 (25%), Positives = 115/279 (41%), Gaps = 43/279 (15%)
Query: 281 LQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPK 340
L+ Y R+ ++T+ + ++ + E + + + + LDGT +LVE K
Sbjct: 120 LKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSD--MKRALEKLDGTEVNGRKIRLVED-K 176
Query: 341 EGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSAS 400
G + S ++ R ++ ++ +G K S+SRSRSR S SRS SRS S
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 401 PKRRKSDSGSTSGGSKSQSRSRS---------------------------RSDSPPRQAP 433
R +S + SK +SRSRS +S SP R
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 434 RSAPY------------KGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPG 481
+S +GS RG + K + + +S+ S SRSRSRS+ + G
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 482 KYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
+ K+ R + R RS+S R +RD S ++
Sbjct: 357 R-KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394
Score = 69.7 bits (169), Expect = 6e-12
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 10/177 (5%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSR 397
SP + K S + K+ + + A++ ++ G PK R S SR +S+ +S SRS R
Sbjct: 249 SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR-SPSRHKSKSKSRSRSQER 307
Query: 398 SASPKRRKSDS-GSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQ 456
++R S S G + S QSRSRSRS R RS + +G ++S++ +
Sbjct: 308 RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE----E 363
Query: 457 KPHKSRSRS-SSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDH 512
+SRSRS S RSR R +R G KKK D R +SRS R+ + ER+H
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK--EDTDRSQSRSPSRSVSK-EREH 417
Score = 67.0 bits (162), Expect = 4e-11
Identities = 63/193 (32%), Positives = 83/193 (43%), Gaps = 31/193 (16%)
Query: 336 VESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRS-RSRSREQSYSRS 394
VE K G S+ + R K + S K ++ R R RSRE+S SRS
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS 368
Query: 395 PSRSASPKRRKSDS--GSTSGGSK---------SQSRSRSRSDSPPRQAPRSAPYK---- 439
SRS S + RK S S +G SK SQSRS SRS S R+ +S +
Sbjct: 369 RSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGR 428
Query: 440 --------GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYR 491
E R +S P P +SRSRS S S++RSR ++ + R
Sbjct: 429 GESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS-------RSRSASR 481
Query: 492 DQRRERSRSYERT 504
R RSRS+ R+
Sbjct: 482 SPSRSRSRSHSRS 494
Score = 61.6 bits (148), Expect = 2e-09
Identities = 60/188 (31%), Positives = 85/188 (45%), Gaps = 22/188 (11%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSR 397
SP K S ++ +RR+E K+ + R+SRSRSRS+ S SRS SR
Sbjct: 290 SPSRHKSKSKS--RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 398 SASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRK-SKDCKYPQ 456
S S +RK G +S+SRSRSRS S + S RGS++ SK +
Sbjct: 348 SKSKDKRK---GRKRSREESRSRSRSRSKS-----------ERSRKRGSKRDSKAGSSKK 393
Query: 457 KPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQ-----RRERSRSYERTGRRYERD 511
K + RS SRS SRS + K + R + + +RS R+ + + +
Sbjct: 394 KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
Query: 512 HPGHSRHR 519
P SR R
Sbjct: 454 LPSESRSR 461
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 11/137 (8%)
Query: 301 RKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLE 360
RK + EE+++++R G+ S A + KE S ++ + E
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416
Query: 361 GAKKAKADSPVNGLPKG----RESRSRSRSREQ------SYSRSPSRSASPKRRKSDSGS 410
AK + G + +E+RSRSRS + S SRS S+SAS R +S S S
Sbjct: 417 HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476
Query: 411 TSGGSKSQSRSRSRSDS 427
S S+S SRSRSRS S
Sbjct: 477 RS-ASRSPSRSRSRSHS 492
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 71.2 bits (173), Expect = 2e-12
Identities = 59/143 (41%), Positives = 73/143 (51%), Gaps = 17/143 (11%)
Query: 365 AKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSR 424
A + N R SRS+SRS S+SRS SRS+SP +S S S S S S S+SRSR
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRSRSRSSSS-SQSRSR 242
Query: 425 SDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQK-PHKSRSRSSSRSRSRSRERADNPGKY 483
S S R R + + S SR + P+K + S S S R+R RSR R+ + G
Sbjct: 243 SSSRERSRSRGSKSRSS----SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR 298
Query: 484 KKKSHYYRDQRRERSRSYERTGR 506
KK RR RSRS ER R
Sbjct: 299 KK--------RRTRSRSPERRHR 313
Score = 58.2 bits (139), Expect = 2e-08
Identities = 49/144 (34%), Positives = 68/144 (47%), Gaps = 6/144 (4%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSR 397
S +E K S ++ R +++ SP + + R SRSRS S QS SRS SR
Sbjct: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR-SRSRSSSSSQSRSRSSSR 246
Query: 398 SASPKR---RKSDSGSTSGGSKSQSRS-RSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCK 453
S R +S S S G S + RS S S SP R RS S ++ +
Sbjct: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
Query: 454 YPQKPHKSRSRSS-SRSRSRSRER 476
P++ H+S S SS S SRS S+++
Sbjct: 307 SPERRHRSSSGSSHSGSRSSSKKK 330
Score = 53.5 bits (127), Expect = 5e-07
Identities = 54/186 (29%), Positives = 72/186 (38%), Gaps = 10/186 (5%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSA 399
K+ +G P S+ E + + + K E + Y+ S
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEE 191
Query: 400 SPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPH 459
++KS+ S S S SRS SRS SP RS S R S S+
Sbjct: 192 DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR----SRSRSSSSSQSRSRSSSRE 247
Query: 460 KSRSR-SSSRSRSRSRERADNPGK---YKKKSHYYRDQRRERSRSYERTGR--RYERDHP 513
+SRSR S SRS SRS + +P K S R+++R RSRS R R R
Sbjct: 248 RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307
Query: 514 GHSRHR 519
RHR
Sbjct: 308 PERRHR 313
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 444 RGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYER 503
R SR + + +S S SSSRSRSRSR R+ + + + +S RERSRS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS-----SSRERSRSRGS 254
Query: 504 TGRRYERDHPGHSRHRR 520
R R H G S R+
Sbjct: 255 KSRSSSRSHRGSSSPRK 271
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 69.3 bits (168), Expect = 8e-12
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 2/170 (1%)
Query: 353 KNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTS 412
K KRR ++ + R SRSRSR R S SRS RS SP+RR+S S
Sbjct: 242 KEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERG 301
Query: 413 GGSKSQSRSR-SRSDSPPRQAPRSAPYKGSEIRGSRK-SKDCKYPQKPHKSRSRSSSRSR 470
S+S S++R + + ++ ++ P S R SR S++ + + +RS RS
Sbjct: 302 RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSP 361
Query: 471 SRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
R R+ +P ++KK+ +D+ R R T ++ + R R+
Sbjct: 362 KRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411
Score = 55.8 bits (133), Expect = 9e-08
Identities = 49/181 (27%), Positives = 86/181 (47%), Gaps = 15/181 (8%)
Query: 336 VESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSP 395
+E K+ + + S ++ +RR + + + + +SRSR RS+ RS
Sbjct: 237 IEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSH 296
Query: 396 SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPR-----QAPRSAPYKGSEIRGSRKSK 450
SR + R+S S S + K + + + RS +PP+ + RSA + R ++
Sbjct: 297 SRE---RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTR 353
Query: 451 DCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYER 510
K P+ P + SRS S R + ++ D K K++S RD+ RERS S ++ + E+
Sbjct: 354 SPKKPRSPKRKLSRSPSPRRHKKEKKKD---KDKERS---RDE-RERSTSKKKKSKDKEK 406
Query: 511 D 511
D
Sbjct: 407 D 407
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/157 (24%), Positives = 64/157 (40%), Gaps = 13/157 (8%)
Query: 330 SPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ 389
SP + S + G+ S+ + K ++ E +K ++ +P R SRS SR R +
Sbjct: 289 SPRRRRSHSRERGRRSRSTS---KTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
Query: 390 ----SYSRSPSRSASPKRRKSDSGST------SGGSKSQSRSRSRSDSPPRQAPRSAPYK 439
S +RSP + SPKR+ S S S K + RSR + + +S +
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE 405
Query: 440 GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRER 476
R S KD K + + + + + E+
Sbjct: 406 KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
Score = 39.7 bits (91), Expect = 0.007
Identities = 38/150 (25%), Positives = 59/150 (39%), Gaps = 14/150 (9%)
Query: 373 GLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQA 432
GLP G S+S + +Q + PK +G S KS + S+ ++ R
Sbjct: 171 GLP-GANLNSQSLAADQLLKLMST--VDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVR 227
Query: 433 -----------PRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPG 481
P K R +S+ + P RSRS SR RS S+ R+
Sbjct: 228 EAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRS 287
Query: 482 KYKKKSHYYRDQRRERSRSYERTGRRYERD 511
K ++ + +R RSRS +T + + D
Sbjct: 288 KSPRRRRSHSRERGRRSRSTSKTRDKKKED 317
Score = 33.5 bits (75), Expect = 0.48
Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 2/121 (1%)
Query: 332 APKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSRE-QS 390
+PK SPK PSP K K++ + K+ D K ++S+ + + RE +S
Sbjct: 354 SPKKPRSPKRKLSRSPSPRRHKKEKKK-DKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
Query: 391 YSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSK 450
S + + + + G S K + + + SP + G +R S+ +
Sbjct: 413 ESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNG 472
Query: 451 D 451
D
Sbjct: 473 D 473
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/222 (31%), Positives = 92/222 (41%), Gaps = 22/222 (9%)
Query: 306 EEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKG--------SKPSPLSVKNTKR 357
EEA A A G T+G PAP P G+ S S S T
Sbjct: 337 EEAAAAAAAAAASGV-----TTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSS 391
Query: 358 RLEGAKKAKADSPVNGLPK-GRESRSRSRS--REQSYSRSPSRSASPKRRKSDSGSTSGG 414
++ + G + GR +RSRSRS R +S SR SRS S RR S GS G
Sbjct: 392 SRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGH 451
Query: 415 SKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSR 474
S+S +R R PR+ RS + G R + + S S S SRSRS +R
Sbjct: 452 RYSRSPAR-RGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTR 510
Query: 475 ERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHS 516
R+ +P + +S + R RS+S + R + P S
Sbjct: 511 SRSHSPSPSQSRS-----RSRSRSQSPSPSPAREKLTRPAAS 547
Score = 57.0 bits (136), Expect = 4e-08
Identities = 57/208 (27%), Positives = 79/208 (37%), Gaps = 46/208 (22%)
Query: 357 RRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSR----------------SAS 400
R++ A+ DSP K S S S SR +S S +P R +A+
Sbjct: 282 RKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAA 341
Query: 401 PKRRKSDSGSTSG-------------GSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSR 447
+ SG T+G G + +R RS S S A R++ + S SR
Sbjct: 342 AAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSR 401
Query: 448 KSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQR------------- 494
+ Y + +RSRS S SRSRSR R + + + + H R
Sbjct: 402 SRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRG 461
Query: 495 ----RERSRSYERTGRRYERDHPGHSRH 518
R RSRS +G RY R G H
Sbjct: 462 GYGPRRRSRSRSHSGDRYRRGGRGLRHH 489
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/207 (28%), Positives = 75/207 (36%), Gaps = 43/207 (20%)
Query: 352 VKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPK---RRKSDS 408
++ K E K AKA + GR RSR + RE R R SP RR S +
Sbjct: 239 LRKDKEEAEAIKHAKALEEEKAMYSGR--RSRRQRREFREKRLRGRKISPPSYARRDSPT 296
Query: 409 GSTSGGSKSQSR----SRSRSDSPPRQ-------------------------------AP 433
S S+S SRSRS +P R+ P
Sbjct: 297 YDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKP 356
Query: 434 RSAPYKGSEIRGSRKSKDCKYPQKPHKSRS--RSSSRSRSRSRERADNPGKYKKKSHYYR 491
+ P G G S + S + SSSRS SRS R+ G Y + + R
Sbjct: 357 PAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHAR 416
Query: 492 DQRRERSRSYERTGRRYERDHPGHSRH 518
+ R SRS R+ RRY R RH
Sbjct: 417 SRSRSWSRSRSRS-RRYSRSRSRGRRH 442
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/187 (22%), Positives = 67/187 (35%), Gaps = 15/187 (8%)
Query: 302 KHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEG 361
+H + L P ++ L + SP+P S + PSP + R
Sbjct: 487 RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAA 546
Query: 362 A----KKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKS 417
+ +K K P G G ++ + Q + + A ++ K+D +
Sbjct: 547 SPAVGEKLKKTEPAAGKETGA---AKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQ 603
Query: 418 QSRSRSRSDSPPRQAPRSAPYKGSEIRGSRK-------SKDCKYPQKPHKSRSRSSSRSR 470
Q R + R R K E R + S+ + P P SR SSSR R
Sbjct: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPS-PRYSREYSSSRRR 662
Query: 471 SRSRERA 477
SRSR R+
Sbjct: 663 SRSRSRS 669
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 11/150 (7%)
Query: 380 SRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYK 439
S S+SRSR +S S+SPS S + ++ + S + G K + + P+ P +
Sbjct: 517 SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQE 576
Query: 440 GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRER-- 497
++R +K+ + ++ ++ + + R +ER D +K +RRE+
Sbjct: 577 KLKLR-MQKALNRQFKADKKAAQEKMIQQEHER-QEREDELRAMARKIRMKERERREKER 634
Query: 498 ---SRSYERTGR----RYERDHPGHSRHRR 520
R Y R R RY R++ R R
Sbjct: 635 EEWERQYSRQSRSPSPRYSREYSSSRRRSR 664
Score = 38.9 bits (89), Expect = 0.012
Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 20/141 (14%)
Query: 380 SRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQ---APRSA 436
S S SRSR + SRS S S S R S+S+SRS+S S SP R+ P ++
Sbjct: 499 SLSPSRSRSLTRSRSHSPSPSQSR-----------SRSRSRSQSPSPSPAREKLTRPAAS 547
Query: 437 PYKGSEIR----GSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKK--KSHYY 490
P G +++ + K P+ + + + + + +AD +K + +
Sbjct: 548 PAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHE 607
Query: 491 RDQRRERSRSYERTGRRYERD 511
R +R + R+ R R ER+
Sbjct: 608 RQEREDELRAMARKIRMKERE 628
Score = 31.2 bits (69), Expect = 2.4
Identities = 24/54 (44%), Positives = 29/54 (53%), Gaps = 9/54 (16%)
Query: 376 KGRESRSRSRSR-EQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSP 428
K RE R + R E+ YSR SRS SP+ + S S + RSRSRS SP
Sbjct: 625 KERERREKEREEWERQYSRQ-SRSPSPRYSREYSSS-------RRRSRSRSRSP 670
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 67.4 bits (163), Expect = 3e-11
Identities = 68/220 (30%), Positives = 99/220 (45%), Gaps = 24/220 (10%)
Query: 281 LQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVES-P 339
L+ + R+ ++T+ + E+ + E ++ + + LDGT +L+E P
Sbjct: 126 LKDFMRQAGEVTYADAHKERTNEGVIEFRSYSD--MKRALDKLDGTEINGRNIRLIEDKP 183
Query: 340 KEG-KGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSP--- 395
+ + S S ++RR + + S + K R SRSRSRS+ +S SRS
Sbjct: 184 RTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR-SRSRSRSKGRSRSRSKGRK 242
Query: 396 SRSASPKRRKSDSGSTSGGSK------SQSRSRSRSDSPPRQAPRSAPYKGSEIRGSR-- 447
SRS S + KSD GS S +SRSRSRS SP K SR
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSN 302
Query: 448 --------KSKDCKYPQKPHKSRSRSSSRSRSRSRERADN 479
K++ P K SRSRS SRS+SRSR R+ +
Sbjct: 303 SPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
Score = 58.9 bits (141), Expect = 1e-08
Identities = 48/124 (38%), Positives = 64/124 (51%), Gaps = 19/124 (15%)
Query: 353 KNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ-SYSRSPSRSASPKRRKSDSGST 411
K K R + K K+D +G S SRSRS+++ SRS SRS SPK ++G
Sbjct: 239 KGRKSRSKSKSKPKSD-------RGSHSHSRSRSKDEYEKSRSRSRSRSPK----ENGKG 287
Query: 412 SGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRS 471
SKS+SRS+SRS+SP P S+ R + +SRS+S SRSRS
Sbjct: 288 DIKSKSRSRSQSRSNSP-------LPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
Query: 472 RSRE 475
SR+
Sbjct: 341 SSRD 344
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/131 (37%), Positives = 63/131 (48%), Gaps = 26/131 (19%)
Query: 376 KGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRS 435
K R S RS S +S SRS RS S RR S S S S SKS+SRSRSRS
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSI-SKSRSRSRSRS---------- 230
Query: 436 APYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRR 495
KG R +SK K SRS S+S+ +S + + + + K Y + + R
Sbjct: 231 ---KG---RSRSRSKGRK---------SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR 275
Query: 496 ERSRSYERTGR 506
RSRS + G+
Sbjct: 276 SRSRSPKENGK 286
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/123 (37%), Positives = 57/123 (46%), Gaps = 15/123 (12%)
Query: 386 SREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRG 445
S +SYS S SRS S +R +S S + SRSRSRS S R RS S R
Sbjct: 186 SHRRSYSGSRSRSRSRRRSRSRS-------RRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238
Query: 446 SRKSKDCKYPQKPHKSR-SRSSSRSR-------SRSRERADNPGKYKKKSHYYRDQRRER 497
+ K KP R S S SRSR SRSR R+ +P + K + + R +
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
Query: 498 SRS 500
SRS
Sbjct: 299 SRS 301
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 5/134 (3%)
Query: 301 RKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLE 360
R +I ++++++R G ++ + G K PK +GS S +
Sbjct: 215 RSRSISKSRSRSRSRSKGRSR--SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKS 272
Query: 361 GAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSR 420
++ NG KG + +S+SRSR QS S SP K R S+S+SR
Sbjct: 273 RSRSRSRSPKENG--KG-DIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSR 329
Query: 421 SRSRSDSPPRQAPR 434
SRS+S S R + R
Sbjct: 330 SRSKSRSRSRSSSR 343
Score = 42.7 bits (99), Expect = 8e-04
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 397 RSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQ 456
RS S +R D G++ R+ + PR + R + Y GS R + +
Sbjct: 154 RSYSDMKRALDK---LDGTEINGRNIRLIEDKPRTSHRRS-YSGSRSRSRSRRRS----- 204
Query: 457 KPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHS 516
+SRSR SSRSRSRS ++ + + + K + +SRS ++ + +R HS
Sbjct: 205 ---RSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHS 261
Query: 517 RHR 519
R R
Sbjct: 262 RSR 264
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 66.6 bits (161), Expect = 5e-11
Identities = 59/194 (30%), Positives = 83/194 (42%), Gaps = 34/194 (17%)
Query: 354 NTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYS---------------RSPSRS 398
N+K R K D N + K +S+SRS+S+E+S S RS S+
Sbjct: 432 NSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKG 491
Query: 399 ASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRS----APYKGSEIRGSRKSKDCKY 454
+ K + K Q RSRS+ S ++ + + K + R +S++C
Sbjct: 492 RDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDI 551
Query: 455 PQKPHKSRSRSSSRSRSRSRERA------DNPGKYKKKSHYYRDQ---RRERSRSYERTG 505
+ H SR+ RSRSR R R D K+ H YR+Q RR RSRS ER
Sbjct: 552 TKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRER-- 609
Query: 506 RRYERDHPGHSRHR 519
R PG SR +
Sbjct: 610 ----RTPPGRSRSK 619
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/185 (25%), Positives = 78/185 (42%), Gaps = 9/185 (4%)
Query: 337 ESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPS 396
E + KG K ++LE +K++ + K ++ R++SRSRE ++
Sbjct: 501 EKQSDSKGKDQERSRSKEKSKQLE----SKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556
Query: 397 RSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQ 456
S R +S S S +S++ R RS S R Y+ RG +S++ + P
Sbjct: 557 SYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR---RGRSRSRERRTPP 613
Query: 457 KPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRY--ERDHPG 514
+S+ R R SRS ER ++ + K K + R + E R Y RDH
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNS 673
Query: 515 HSRHR 519
+ R
Sbjct: 674 SNNSR 678
Score = 50.8 bits (120), Expect = 3e-06
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 17/197 (8%)
Query: 337 ESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPS 396
+S ++ K + +N ++R+ K + V K ++S S+ + +E+S S+ S
Sbjct: 463 KSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVK--EKEKQSDSKGKDQERSRSKEKS 520
Query: 397 RSASPKRRKSD-SGSTSGGSKSQSRSRSRS--------DSPPRQAPRSAPYKGSEIRGSR 447
+ K + D S S ++QSRSR +S R+ RS + +R
Sbjct: 521 KQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD-RSRRVRSRT 579
Query: 448 KSKDCKYPQKPHKSRS---RSSSRSRSRSRERADNPGKYKKKSHYYRDQR-RERSRSYER 503
+D ++ H+ R R RSRSR R + K + RD R ER S R
Sbjct: 580 HDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSR 639
Query: 504 TGRRYERDHPGHSRHRR 520
+Y R+ S HR+
Sbjct: 640 NKDKY-RNQESKSSHRK 655
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/199 (23%), Positives = 76/199 (38%), Gaps = 29/199 (14%)
Query: 343 KGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPK 402
KG K +K +R K+ K N + + + S S R
Sbjct: 382 KGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRN 441
Query: 403 RRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSE---IRGSRKSKDCK-YPQKP 458
K D +++S+SRS+S + R + + +E +R K +D + +K
Sbjct: 442 SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE 501
Query: 459 HKSRSRSSSRSRSRSRERA---------DNPGKYKKK----------------SHYYRDQ 493
+S S+ + RSRS+E++ + K K+K H Y +
Sbjct: 502 KQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSR 561
Query: 494 RRERSRSYERTGRRYERDH 512
RERSRS +R+ R R H
Sbjct: 562 TRERSRSRDRSRRVRSRTH 580
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 7/199 (3%)
Query: 295 EGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKN 354
E EK K + + K Q R ++ L+ S K E + + S+ +
Sbjct: 495 ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQ-SRSRECDITK 553
Query: 355 TKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGG 414
K + ++ S + R RSR+ R++S S+ R + R+ +
Sbjct: 554 GKHSYNSRTRERSRSR----DRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRER 609
Query: 415 SKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSR 474
RSRS+ R+ RS+ + S+ R K ++ + K S S R S+SR
Sbjct: 610 RTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSR 669
Query: 475 ERADNPGKYKKKSHYYRDQ 493
+ + +KK+ RDQ
Sbjct: 670 DHNSSNNSREKKAD--RDQ 686
Score = 40.4 bits (93), Expect = 0.004
Identities = 37/176 (21%), Positives = 71/176 (40%), Gaps = 16/176 (9%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSA 399
KE K S S ++ + + +++ S + E +S+ R ++ + +
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE 244
Query: 400 SPKRRKSDSGSTSGGS----KSQSRSRSRSDSPP---------RQAPRSAPYKGSEIRGS 446
KR+KS ++S ++Q +S R + P R++P A K + R
Sbjct: 245 KKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRER 304
Query: 447 RKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYE 502
+ ++C P S R +RS + + P +Y+ S R + R+R R E
Sbjct: 305 ERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS---RSRSRDRFRRSE 357
Score = 35.8 bits (81), Expect = 0.097
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 350 LSVKNTKRRLEGAKKAKADSP---VNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKS 406
+S + R +E K A P V L G E +S+ +++ R S S+S S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCG-ELIPKSKVKKEEKKRHKSSSSS-----S 198
Query: 407 DSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSS 466
S S S S S SDS +S K + SRK K K +K KS+ +S
Sbjct: 199 SSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHK--KEKKKRKKSKKSAS 256
Query: 467 SRSRSRSRE 475
S S + + E
Sbjct: 257 SESEAENLE 265
Score = 34.3 bits (77), Expect = 0.28
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 19/188 (10%)
Query: 339 PKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRS 398
P S L V + R+++G + +P SRSRSR R + S +P
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP---------SRSRSRDRFRR-SETPPHW 362
Query: 399 ASPKRRKSDSGSTSG-----GSKSQ-SRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDC 452
+R +SG G KS+ + + SP R R + + +
Sbjct: 363 RQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEK 422
Query: 453 KYPQKPHKSRSRSSS-RSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERD 511
+ K HKS S+ R S ++ N K + KS R + +E+S+S ER ++ R+
Sbjct: 423 EKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKS-RSKSKEKSKSKERDS-KHNRN 480
Query: 512 HPGHSRHR 519
R R
Sbjct: 481 EEKRMRSR 488
Score = 29.6 bits (65), Expect = 7.0
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 8/71 (11%)
Query: 448 KSKDCKYPQKPHKSRSRSSSRS--------RSRSRERADNPGKYKKKSHYYRDQRRERSR 499
KSK K +K HKS S SSS S S + +D+ ++KS + + R+ SR
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 500 SYERTGRRYER 510
+++ ++ ++
Sbjct: 240 KHKKEKKKRKK 250
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 66.6 bits (161), Expect = 5e-11
Identities = 59/176 (33%), Positives = 91/176 (51%), Gaps = 23/176 (13%)
Query: 353 KNTKRR--LEGAKKAKADS---PVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSD 407
+NT+RR A++ ++ S G + R R RSR ++ +R SRS +P RR+S
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
Query: 408 SGSTSGGSKSQSRS----RSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRS 463
S + + +S+SR+ RSR+ SP R+ RS S R S +S+ + P + +SRS
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSR----SPARRSGRSRS-RTPARRGRSRS 660
Query: 464 RS-SSRSRSRSRERADNPGKYKKKSHYYRDQR--------RERSRSYERTGRRYER 510
R+ + R RSRSR A G+ + ++ R + R RSRS R GR + R
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Score = 65.1 bits (157), Expect = 1e-10
Identities = 75/224 (33%), Positives = 96/224 (42%), Gaps = 33/224 (14%)
Query: 317 PGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPK 376
P T+V S +PK +P + SP S K R G +AK D + P
Sbjct: 425 PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS----KNRSHG--RAKRDKSHSHTPS 478
Query: 377 GRESRSRSRS---REQSYSRSP-----SRSASPKRRKSDSGSTSGGSKS-QSRSRSRSDS 427
R RSRS + R +S SR+P SRS SP+ R+S S G S+S Q R RSRS
Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 428 PP----------RQAPRSAPYKGSEIRG--SRKSKDCKYPQKPHKSRSRSSSRSRSRSRE 475
P R RSA S R +R + P + +SRSR+ +R RSRSR
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598
Query: 476 RADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHR 519
+++S RR RSRS RR P R R
Sbjct: 599 PT------RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636
Score = 64.3 bits (155), Expect = 3e-10
Identities = 56/183 (30%), Positives = 89/183 (48%), Gaps = 21/183 (11%)
Query: 342 GKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASP 401
G+ +P ++ R +++++ +P + R R RSR ++ +R SR+ SP
Sbjct: 571 GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP 630
Query: 402 KRRKSDSGS---TSGGSKSQS---RSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYP 455
RR+S S S SG S+S++ R RSRS +P R R + R S +S+ + P
Sbjct: 631 VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR---RGRSRSRTPARRSGRSRS-RTP 686
Query: 456 QKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERS------RSYERTGRRYE 509
+ +SRSR+ R RSRSR + +SH QRR RS ++ RT +R
Sbjct: 687 ARRGRSRSRTPRRGRSRSRSLV-----RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRS 741
Query: 510 RDH 512
R +
Sbjct: 742 RSN 744
Score = 60.8 bits (146), Expect = 3e-09
Identities = 63/211 (29%), Positives = 89/211 (42%), Gaps = 28/211 (13%)
Query: 308 AKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKA 367
+ ++ RG P G+ + + P + + + G S P P TK R +++
Sbjct: 1640 SSSKGRGPSPEGSSSTESSPEHPPKSR---TARRGSRSSPEP----KTKSRTPPRRRSSR 1692
Query: 368 DSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDS-GSTSGGSKSQSRSRSRSD 426
SP R++R RSR S S P+ R+S S S KS+S R RS
Sbjct: 1693 SSP----ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 427 SPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKK 486
S PR K + RG S P+ +SRSRS R ++R+ R D G +
Sbjct: 1749 SSPRT-------KTTSRRGRSPSPK---PRGLQRSRSRSR-REKTRTTRRRDRSGSSQST 1797
Query: 487 SHYYRDQRRERSRSYERTGRRYERDHPGHSR 517
S +RR+RSRS R RR HSR
Sbjct: 1798 S-----RRRQRSRSRSRVTRRRRGGSGYHSR 1823
Score = 60.5 bits (145), Expect = 4e-09
Identities = 53/155 (34%), Positives = 78/155 (50%), Gaps = 18/155 (11%)
Query: 355 TKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGG 414
T+RR A+ + P R SR+RS R +S SRSP+R + R +S + + G
Sbjct: 600 TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG--RSRSRTPARRGR 657
Query: 415 SKSQS---RSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSS---- 467
S+S++ R RSRS +P R++ RS + RG +S+ P + RSRS S
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPAR-RGRSRSR------TPRRGRSRSRSLVRR 710
Query: 468 -RSRSRSRERADNPGKYKKKSHYYR-DQRRERSRS 500
RS SR+ +R G ++ + R QRR RS S
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745
Score = 60.5 bits (145), Expect = 4e-09
Identities = 57/199 (28%), Positives = 89/199 (44%), Gaps = 25/199 (12%)
Query: 332 APKLVESPKEGKGSKPSPLSVKNTKRRLEGAK------KAKADSPVNGLPKGRESRSRSR 385
+P+ + + G+ P P ++ ++ R K + ++ S + + + SRSRSR
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Query: 386 SREQSYSRSPSRSASPKRRKSDSGSTS---GGSKSQ--SRSRSRSDSPPRQAPRSAPYKG 440
+ S S SP R++S S+ G S++ SR RSRS + P AP+K
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP------APWKR 1863
Query: 441 SEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRS 500
S R S P +SRSR+ SR RSR R + + +S +RR RSR+
Sbjct: 1864 SRSRAS--------PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA 1915
Query: 501 YERTGRRYERDHPGHSRHR 519
+ RR P +R R
Sbjct: 1916 SPVSRRRSRSRTPPVTRRR 1934
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/175 (29%), Positives = 71/175 (40%), Gaps = 18/175 (10%)
Query: 345 SKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRR 404
S P P + RR A + + +GR + R ++S SRS RR
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSR---RGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 405 KSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSR 464
+ SGS+ S+ + RSRSRS R R G R + + + + + RSR
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRS----RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
Query: 465 SSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHR 519
+ SR RSR R +P +K R RSR+ T RR P SR R
Sbjct: 1844 TPPTSRKRSRSRT-SPAPWK----------RSRSRASPATHRRSRSRTPLISRRR 1887
Score = 59.3 bits (142), Expect = 8e-09
Identities = 63/223 (28%), Positives = 91/223 (40%), Gaps = 35/223 (15%)
Query: 330 SPAPKLVESPKEGKGSKPSPLSVKNT----KRRLEGAKKAKADSPVNGLPKGRESRSRS- 384
SP PK + + PS + N +R G++ + V P G+ SRS S
Sbjct: 1483 SPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSS 1542
Query: 385 -------------RSREQSYSRSPSRSASPKRRKSDSGST----SGGSKSQSRSRSRSDS 427
RS S S +++ +P R++S SGS+ S S RSRS S
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602
Query: 428 PPRQAPRSAPYKGSEIRGSRKSKDCKYPQK---PHKSRSRSSSRSRSRSRERA------- 477
+ PR+AP S GS S + K P P +SRS SSS+ R S E +
Sbjct: 1603 EVKDKPRAAPRAQS---GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP 1659
Query: 478 DNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR 520
++P K + R +++S RR R P +R R
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
Score = 58.2 bits (139), Expect = 2e-08
Identities = 69/225 (30%), Positives = 93/225 (41%), Gaps = 34/225 (15%)
Query: 327 SGFSPA--PKLVESPKEGK-GSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSR 383
SG SP K SP+ + GS P VK+ R A+ SP P R R
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPE---VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR 1635
Query: 384 SRSREQSYSRSPSRSASPKRRKSD-----SGSTSGGSKSQSRSRSRSDSPPRQ-APRSAP 437
SRS S R PS S S S + GS+S +++S +PPR+ + RS+P
Sbjct: 1636 SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695
Query: 438 YKGSEIRGSRKSKDC--------KYPQKPHKS----------RSRSSSRSRSRSRERADN 479
+ R SR+S+ + P + +S +SRSS R RS S R
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 480 PGKY-KKKSHYYRDQRRERSRSYE---RTGRRYERDHPGHSRHRR 520
+ + S R +R RSRS RT RR +R S RR
Sbjct: 1756 TSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800
Score = 55.8 bits (133), Expect = 9e-08
Identities = 66/217 (30%), Positives = 96/217 (44%), Gaps = 25/217 (11%)
Query: 325 GTSGF-SPAPKLVESPKEGKG-----SKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGR 378
G SG+ S +P ES + S+ P S K ++ R A ++ S +
Sbjct: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS---PAT 1872
Query: 379 ESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRS------RSRSDSPPRQA 432
RSRSR+ S RS SR++ RR+S S ++ +S+SR+ RSRS +PP
Sbjct: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 433 PRSAPYKGSEIRGSR---------KSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKY 483
RS + R SR +S+ P +SRSR+S +R RSR R +
Sbjct: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRR 1992
Query: 484 KKKSHYYR-DQRRERSRSYERTGRRYERDHPGHSRHR 519
+ +S +RR RSR+ T RR P R R
Sbjct: 1993 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRR 2029
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/214 (28%), Positives = 86/214 (40%), Gaps = 24/214 (11%)
Query: 330 SPAPKLVESPKEGKGSKPSPLSVKNTK-------RRLEGAKKAKADSPVNGLPKGRESRS 382
SP + KE ++PSP +++ L + + P+ P +E +
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 383 RSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSE 442
+ RSP +S + S S S+ + SR S SP P AP E
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 443 IRGSRKSKDCKYPQ-KPHKSRSRSSS----RSRS-----RSRERADNP---GKYKKKSHY 489
I S SK+ + + K KS S + S RSRS R R R+ P G + +S
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Query: 490 YR----DQRRERSRSYERTGRRYERDHPGHSRHR 519
+R QR RSRS +R GR PG SR R
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546
Score = 54.3 bits (129), Expect = 3e-07
Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 17/191 (8%)
Query: 338 SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRE------SRSRSRSREQSY 391
+P + S+ SP + + ++ R + ++ S + + + R +R RSRSR
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV 1918
Query: 392 SRSPSRSASPK--RRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKS 449
SR SRS +P RR+S S + + +R RSRS +PP RS R R+S
Sbjct: 1919 SRRRSRSRTPPVTRRRSRSRTPT------TRRRSRSRTPPVTRRRSRSRTPPVTR--RRS 1970
Query: 450 KDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYR-DQRRERSRSYERTGRRY 508
+ P +SRSR+S +R RSR R + + +S +RR RSR+ RR
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS 2030
Query: 509 ERDHPGHSRHR 519
P R R
Sbjct: 2031 RSRTPLLPRKR 2041
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/189 (29%), Positives = 78/189 (41%), Gaps = 17/189 (8%)
Query: 345 SKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRS------RSRSREQSYSRSPSRS 398
S+ SP+S + ++ R + ++ S + SR+ RSRSR +R SRS
Sbjct: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
Query: 399 -ASPKRRKSDSGSTSGGSKSQSRSR--------SRSDSPPRQAPRSAPYKGSEIRGSRKS 449
SP R+ TS ++ +SRSR SRS + P RS IR +S
Sbjct: 1973 RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS 2032
Query: 450 KDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYE 509
+ P+K +SRSRS R RSR R + K+ R RS S + R
Sbjct: 2033 RTPLLPRK--RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090
Query: 510 RDHPGHSRH 518
P H
Sbjct: 2091 ATPPATRNH 2099
Score = 50.4 bits (119), Expect = 4e-06
Identities = 57/207 (27%), Positives = 84/207 (40%), Gaps = 11/207 (5%)
Query: 317 PGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPK 376
P T +L G SP P + + PS S + + +K S P
Sbjct: 364 PAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP 423
Query: 377 GRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSR---SRSDSPPRQAP 433
+ SR S SP + +P + S S + ++S R++ S S +P R+
Sbjct: 424 SPQPTKVSRHASSS-PESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG 482
Query: 434 RSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQ 493
RS ++ RG +S+ P K SRSRS RSRS +R +++ Q
Sbjct: 483 RSRSPATAK-RGRSRSRT---PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 494 RR--ERSRSYERTGR-RYERDHPGHSR 517
R RSR+ +R GR R R HSR
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSR 565
Score = 50.4 bits (119), Expect = 4e-06
Identities = 59/212 (27%), Positives = 90/212 (42%), Gaps = 33/212 (15%)
Query: 318 GGTQVLDGTSGFSPAPKLV-ESPKEGKGSKPSPLSVKN---------TKRRLEGAKKAKA 367
G +Q LD SP + +S + K +PL ++ +K RL +
Sbjct: 1540 GSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSG 1599
Query: 368 DSP-VNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSD 426
SP V P+ R++S S ++P+ A P+R S SGS+S G S ++
Sbjct: 1600 SSPEVKDKPRAAP-RAQSGSDSSPEPKAPAPRALPRR--SRSGSSSKGRGPSPEGSSSTE 1656
Query: 427 SPPRQAPRSAPYKGSEIRGSRKSKDCKYPQK--PHKSRSRSS------------SRSRSR 472
S P P+S + RGSR S + K + P + SRSS SRS S
Sbjct: 1657 SSPEHPPKSRTAR----RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712
Query: 473 SRE-RADNPGKYKKKSHYYRDQRRERSRSYER 503
S E R+ P ++++ + E+SRS R
Sbjct: 1713 SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/199 (24%), Positives = 80/199 (40%), Gaps = 4/199 (2%)
Query: 292 THLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLS 351
++++G + EAK A + V + +S SP PK + K+ + S S
Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203
Query: 352 VKNTKRRLEGAKKAKADSPVNGLPKGRES--RSRSRSREQSYSRSPSRSASPKRRKS--D 407
+R+ KK + K R +S+ +S+++ RS S + +PK R++
Sbjct: 204 SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263
Query: 408 SGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSS 467
+ + S S SRSRSRS + A S G R D + + S R SS
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323
Query: 468 RSRSRSRERADNPGKYKKK 486
+ + + K K K
Sbjct: 324 PETATKQPSSPYEDKDKDK 342
Score = 49.3 bits (116), Expect = 9e-06
Identities = 48/180 (26%), Positives = 69/180 (38%), Gaps = 21/180 (11%)
Query: 330 SPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ 389
SP P E+ +EG+ +P+P KRR + + + S + S S S S
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAK---RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
Query: 390 SYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKS 449
S S S S S+SP K G ++ + S PP + +P K I R S
Sbjct: 2638 SSSSSSSSSSSPSPAKP-------GPQALPKPASPKKPPPGERRSRSPRK--PIDSLRDS 2688
Query: 450 KDCKY---------PQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRS 500
+ Y PQ + + SSS SR +R D+ K+ R R RS
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 48.9 bits (115), Expect = 1e-05
Identities = 64/268 (23%), Positives = 106/268 (39%), Gaps = 46/268 (17%)
Query: 250 RTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIEEAK 309
R LE L RP+ +L + ++ CL++ ++ + + ++ +V + + E
Sbjct: 43 RRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLE-- 100
Query: 310 AQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADS 369
+ + PGG + G P + E+ + + ++ KN + R A +DS
Sbjct: 101 ---KDVNPGGKEETPGQR-----PAVTETHQLAELNEK-----KNERLR---AAFGISDS 144
Query: 370 PVNGLPKGRESRSR-------------SRSREQSYSRSPSRSASPKRRKSDSGSTSGGSK 416
V+G + R+R S RE S SRSP+ K++K D G
Sbjct: 145 YVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGR------ 198
Query: 417 SQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRER 476
RS S SP R+ +S+ K K + + P K +S+ R RSRS
Sbjct: 199 -----RSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253
Query: 477 ADNPGKYKKK----SHYYRDQRRERSRS 500
A + + S D R RSRS
Sbjct: 254 APKSRRAHRSTSADSASSSDTSRSRSRS 281
Score = 46.6 bits (109), Expect = 6e-05
Identities = 55/187 (29%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 356 KRRLEGAKKAKADSPVNGLPKGRESRSRSRS---REQSYSRSP------SRSASPKRRKS 406
+RR A+ R RSRSR+ R +S SR+P SRS +P RR
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR 691
Query: 407 DSGSTSGGSKSQSRS-----RSRSDSPPR--QAPRSAPYKGSEIRGSRKSKDCKYPQ--- 456
T +S+SRS RS S +P R ++ S+ K R+S+ P+
Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751
Query: 457 ---KPHKSRSRSSSRSRSRSR---ERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYER 510
+SRS SS RS+++SR R+ + K RR RS S + + R
Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK--SR 809
Query: 511 DHPGHSR 517
P SR
Sbjct: 810 TPPRRSR 816
Score = 46.2 bits (108), Expect = 7e-05
Identities = 54/230 (23%), Positives = 80/230 (34%), Gaps = 36/230 (15%)
Query: 319 GTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGR 378
G Q + PA K S S S S ++ + + +DS + LP
Sbjct: 2514 GAQQPSALAALQPA-KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP 2572
Query: 379 E-------SRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSD----- 426
E S + + R P + + ++R+S S S+S S S S S S S
Sbjct: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
Query: 427 -----------------SPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRS 469
SP + P++ P S + + + P+KP S S S S
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS 2692
Query: 470 RSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHR 519
S R +P RDQ+ S R G+R + P H R R
Sbjct: 2693 YSPVERRRPSPQPSP------RDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Score = 43.1 bits (100), Expect = 6e-04
Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 17/165 (10%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADS--PVNGLPKGRE--SRSRSRSR-EQSYSRS 394
+ G+ +P R A++ ++ S P G + R R RS SR Q RS
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 395 PSRS-----ASPKRRKSDSGSTSGGSKSQ-SRSRSRSDSPPRQAPRSAPYKGSEIRGSRK 448
S S + +R+S S S+ KS+ S RSRS S PR +S + GS
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 449 SKDCKYPQKPHKSRSRSS---SRSRS---RSRERADNPGKYKKKS 487
K P +SRS SS ++SR+ RSR + P K K K+
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT 829
Score = 40.0 bits (92), Expect = 0.005
Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 16/102 (15%)
Query: 345 SKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRS----REQSYSRSP----- 395
S+ SP++ + ++ R A + ++ S LP+ RSRSRS R +S SR+P
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR---KRSRSRSPLAIRRRSRSRTPRTARG 2064
Query: 396 ----SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAP 433
+RS RR+S SGS+S S+S + +R+ S R P
Sbjct: 2065 KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106
Score = 39.3 bits (90), Expect = 0.009
Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 6/171 (3%)
Query: 332 APKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSY 391
+P++ +S + S+ K RL + SP PK + RSR S
Sbjct: 746 SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC---PKQKSQTPPRRSRSGS- 801
Query: 392 SRSPSRSASPKRRKSDSGSTSGGSKSQSRSRS--RSDSPPRQAPRSAPYKGSEIRGSRKS 449
S+ ++S +P RR S S KS++ SR S SP + P + I + +
Sbjct: 802 SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN 861
Query: 450 KDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRS 500
+ PQ+ S +SR+ R G + R+ SRS
Sbjct: 862 EQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRS 912
Score = 38.9 bits (89), Expect = 0.012
Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 14/154 (9%)
Query: 354 NTKRRLEGAKKAKADSPVNGLPKGRESR-SRSRSREQSYSRSPSRSASPKRRKSDSGSTS 412
++ R ++ ++ S N P+ ++SR S RSR S RS ++S RR S
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
Query: 413 GGSKSQS---RSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRS 469
KSQ+ RSRS S S P+ R+ P R+S+ P KS++ S
Sbjct: 786 PKQKSQTPPRRSRSGS-SQPKAKSRTPP---------RRSRSSSSPPPKQKSKTPSRQSH 835
Query: 470 RSRSRERADNPGKYKKKSHYYRDQRRERSRSYER 503
S S G ++ Q E+S + +R
Sbjct: 836 SSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR 869
Score = 36.2 bits (82), Expect = 0.075
Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 7/139 (5%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRES-RSRSRSREQSYSRSPSRS 398
K+ K P+P S + +K KK K PK R + RS S S S SRS
Sbjct: 225 KKRKHRSPTPKSKRKSKD-----KKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS 279
Query: 399 ASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKP 458
S + + S R D+P + ++ + S + K Y K
Sbjct: 280 RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339
Query: 459 HKSRSRSSSRSRSRSRERA 477
+ +S++R S S ER+
Sbjct: 340 KDKKEKSATRP-SPSPERS 357
Score = 34.3 bits (77), Expect = 0.28
Identities = 40/164 (24%), Positives = 64/164 (39%), Gaps = 17/164 (10%)
Query: 327 SGFSPAPKLVESPKEGKGSKPSP-LSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSR 385
S SP PK+ +GS SP + ++ + ++ D + R S S S
Sbjct: 836 SSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSS 895
Query: 386 SREQSYS----RSPSRSASPKRRK----SDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAP 437
S +SPSRS+SP+ + S + GS S S SR S + PR++ +P
Sbjct: 896 PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
Query: 438 YKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPG 481
E R P+ H S ++ + + R + G
Sbjct: 956 CSNVESR--------LLPRYSHSGSSSPDTKVKPETPPRQSHSG 991
Score = 33.5 bits (75), Expect = 0.48
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 326 TSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSR 385
+S SP+P K G + P P S K G ++++ SP + R+SRS S
Sbjct: 2644 SSSSSPSPA-----KPGPQALPKPASPKKPP---PGERRSR--SPRKPIDSLRDSRSLSY 2693
Query: 386 SREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGS 441
S + SP S ++ S + G + SRS S +PR ++ S
Sbjct: 2694 SPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 33.1 bits (74), Expect = 0.63
Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 21/144 (14%)
Query: 330 SPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ 389
SP PK K+ K + + RR + A + S + SRSRSRS
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSD------TSRSRSRSAAA 284
Query: 390 S------YSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEI 443
RSPS AS +R + D+ + G+ S R S + + S+PY+ +
Sbjct: 285 KTHTTALAGRSPS-PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP---SSPYEDKD- 339
Query: 444 RGSRKSKDCKYPQKPHKSRSRSSS 467
K K K +P S RSS+
Sbjct: 340 ----KDKKEKSATRPSPSPERSST 359
Score = 33.1 bits (74), Expect = 0.63
Identities = 32/138 (23%), Positives = 46/138 (33%), Gaps = 20/138 (14%)
Query: 370 PVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPP 429
P G+P + + Q S + + +RR S S S+S S S S S S S S
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556
Query: 430 --------------------RQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRS 469
++ P P +R R + +K S S SSS S
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 470 RSRSRERADNPGKYKKKS 487
S S + + S
Sbjct: 2617 SSSSSSSSSSSSSSSSSS 2634
Score = 30.4 bits (67), Expect = 4.1
Identities = 40/163 (24%), Positives = 64/163 (39%), Gaps = 13/163 (7%)
Query: 323 LDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRS 382
L G S SP + S E + S S+++ + ++++ SPV L SRS
Sbjct: 1057 LKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL----ASRS 1112
Query: 383 RSRSREQSYSRSP----SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPY 438
R +S SP S R +SDS S + +SR ++ + + P
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172
Query: 439 KGSEIRGSRKSKDCKYPQKPHKSRSRSS----SRSRSRSRERA 477
+ + KD K+ P + R SS R+ RER+
Sbjct: 1173 QEDATASPPRQKD-KFSPFPVQDRPESSLVFKDTLRTPPRERS 1214
Score = 30.4 bits (67), Expect = 4.1
Identities = 27/120 (22%), Positives = 43/120 (35%), Gaps = 3/120 (2%)
Query: 317 PGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPK 376
P ++ S + AP + + P+ L+ L GA P++ +
Sbjct: 2333 PASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYER 2392
Query: 377 --GRESRSR-SRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAP 433
GR S R+R ++ +PS+S R S G + SQS D P P
Sbjct: 2393 VSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP 2452
Score = 29.3 bits (64), Expect = 9.1
Identities = 52/176 (29%), Positives = 68/176 (38%), Gaps = 31/176 (17%)
Query: 325 GTSGFSPAPKLVESPKEGKGSKPSPLS-----VKNTKRRLEGAKKAKADSPVNGLPKGRE 379
G S +P VE K G S S S V T R E + A + +GLP+
Sbjct: 1380 GHSSSELSPDAVE--KAGMSSNQSISSPVLDAVPRTPSR-ERSSSASSPEMKDGLPRTPS 1436
Query: 380 SRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSK-SQSRSRSRSDSPPRQAPRSAPY 438
RSRS S S + S R S SGS+ G ++ SR RS+ P++ P
Sbjct: 1437 RRSRSGSSPGLRDGSGTPS-----RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491
Query: 439 KGSEIRGSRKSKD----CKYPQKPHKSRSRSS------------SRSRSRSRERAD 478
S S + C PQ+ +S S SS RSRS S + D
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQR-ERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 66.2 bits (160), Expect = 7e-11
Identities = 61/206 (29%), Positives = 86/206 (41%), Gaps = 26/206 (12%)
Query: 340 KEGKGSKPSPLSVKNTKRRL----EGAKKAKADSPVNGLPKGRESR-SRSRSREQSYSRS 394
+EG GS ++ K R E ++ K + +G E R SRSR R +S SRS
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS 342
Query: 395 PSRSAS--------------PKRRKSDSGSTSGGSKSQSRSRSRSDS-PPRQAPRSAPYK 439
R +RR D G + + R RSR S R K
Sbjct: 343 RDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKK 402
Query: 440 GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRS-RSRERADNPGK-----YKKKSHYYRDQ 493
E + R+ +D K K K SRS SR R RSR R+ N GK K+KS ++++
Sbjct: 403 HKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE 462
Query: 494 RRERSRSYERTGRRYERDHPGHSRHR 519
+E+S R+G + D S+ R
Sbjct: 463 SKEKSNKRSRSGSQGRTDSVEKSKKR 488
Score = 60.8 bits (146), Expect = 3e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 353 KNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTS 412
++ +R E + + D + + R RSRE+S + K+ K D
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRR 411
Query: 413 ------GGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSS 466
K + SRSRS ++ + G R K K K+ ++S+ +S+
Sbjct: 412 HRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHK---NESKEKSN 468
Query: 467 SRSRSRSRERADNPGKYKKKSHY-YRDQRRERSRSYERTGRRYERDHPGHS-RHRR 520
RSRS S+ R D+ K KK+ H +++ R+RSRS ER+ +R D S +H R
Sbjct: 469 KRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDR 524
Score = 56.6 bits (135), Expect = 5e-08
Identities = 55/209 (26%), Positives = 89/209 (42%), Gaps = 22/209 (10%)
Query: 324 DGTSGFSPAPKLVE-----SPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGR 378
DG G + VE SP+ + SP ++ EG + D + + +
Sbjct: 243 DGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQ 302
Query: 379 ESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPY 438
++ RE+ RS S +RR+S S + +SRSRSR R+
Sbjct: 303 RLEREAKEREKERRRSRSIDRGLERRRSRS-----RERHRSRSRSRDRKGDRRDRDRERE 357
Query: 439 KGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSH-------YYR 491
K +E RG R+ +D Y ++ R + RSR RS+E+ G+ ++K H +R
Sbjct: 358 KENE-RGRRRDRD--YDKERGNEREKERERSRERSKEQRSR-GEVEEKKHKEDKDDRRHR 413
Query: 492 DQRRERSRSYERT-GRRYERDHPGHSRHR 519
D +R+ + + + R ER H SR R
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSR 442
Score = 54.7 bits (130), Expect = 2e-07
Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 21/176 (11%)
Query: 337 ESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPS 396
E +E + S V+ K + + + D + + + SRSRSR R+ SRS S
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR-SRSRS 441
Query: 397 RSA---SPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCK 453
R+A S R K S SK +S RSRS S R KSK +
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD------------SVEKSKKRE 489
Query: 454 YPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYE 509
+ KSR RS S+ RS R+ +D+ + K D+RR +S E ++++
Sbjct: 490 HSPSKEKSRKRSRSKERSHKRDHSDSKDQSDK-----HDRRRSQSIEQESQEKQHK 540
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/136 (24%), Positives = 51/136 (37%), Gaps = 12/136 (8%)
Query: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGS 410
S K K +++ K S G+ SRSRS+ + + ++ + R G
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGR 478
Query: 411 TSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSR 470
T KS+ R S S R+ RS K + K K +S R R
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRS------------KERSHKRDHSDSKDQSDKHDRRR 526
Query: 471 SRSRERADNPGKYKKK 486
S+S E+ ++K K
Sbjct: 527 SQSIEQESQEKQHKNK 542
Score = 37.7 bits (86), Expect = 0.026
Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 5/131 (3%)
Query: 337 ESPKEGKGSKPSPLSVKNTKRRLE--GAKKAKADSPVNGLPKGRESRSRSRSREQSYSRS 394
+S KE K S+ K+ R K++++ S ES+ +S R +S S+
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQG 477
Query: 395 PSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKY 454
+ S +++ S S KS+ RSRS+ S R S R +S + +
Sbjct: 478 RTDSVEKSKKREHSPSKE---KSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQES 534
Query: 455 PQKPHKSRSRS 465
+K HK++ +
Sbjct: 535 QEKQHKNKDET 545
Score = 34.7 bits (78), Expect = 0.22
Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 5/100 (5%)
Query: 332 APKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGL-----PKGRESRSRSRS 386
A K S + K SK S + + +R + + DS P +SR RSRS
Sbjct: 444 AGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRS 503
Query: 387 REQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSD 426
+E+S+ R S S + S S +SQ + D
Sbjct: 504 KERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 65.9 bits (159), Expect = 9e-11
Identities = 56/145 (38%), Positives = 71/145 (48%), Gaps = 29/145 (20%)
Query: 365 AKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSR 424
A + N R SRS+SRS S+SRS SRS+SP S+S+SRSRSR
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPS-----------SSRSRSRSRSR 232
Query: 425 SDSPPRQAPRSAPYKGSEIRG------SRKSKDCKYPQK-PHKSRSRSSSRSRSRSRERA 477
S S + RS+ + S RG SR + P+K + S S S R+R RSR R+
Sbjct: 233 SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Query: 478 DNPGKYKKKSHYYRDQRRERSRSYE 502
+ G KK RR RSRS E
Sbjct: 293 SSSGDRKK--------RRTRSRSPE 309
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/175 (28%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSA 399
K+ +G P S+ E + + + K E + Y+ S
Sbjct: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEE 191
Query: 400 SPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPH 459
++KS+ S S S SRS SRS SP RS S R S S+
Sbjct: 192 DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR----SRSRSSSSSQSRSRSSSRE 247
Query: 460 KSRSR-SSSRSRSRSRERADNPGK---YKKKSHYYRDQRRERSRSYERTGRRYER 510
+SRSR S SRS SRS + +P K S R+++R RSRS R+ R
Sbjct: 248 RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR 302
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 7/101 (6%)
Query: 338 SPKEGKGSKPSPLSVKNTKR-RLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSP- 395
S + S PS ++ R R + ++++ S + R S+SRS SR S SP
Sbjct: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
Query: 396 -----SRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQ 431
S S+SP+R + S S S S + + R+RS SP Q
Sbjct: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQ 311
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 65.9 bits (159), Expect = 9e-11
Identities = 51/121 (42%), Positives = 64/121 (52%), Gaps = 11/121 (9%)
Query: 352 VKNTKRRLEGAK-KAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGS 410
+KN +L G + + + G + SRSRSRSR +S SRS SRS S R+
Sbjct: 157 LKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSY---- 212
Query: 411 TSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSR 470
S+S+SRSRSRS S R RS + S+ RGS S K P + RSRS SRSR
Sbjct: 213 ----SRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGS--SSRSKSPASVDRQRSRSRSRSR 266
Query: 471 S 471
S
Sbjct: 267 S 267
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/102 (42%), Positives = 52/102 (50%), Gaps = 24/102 (23%)
Query: 414 GSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRS 473
GSK SRSRSRS S R + RS S SRKS SRSRS SRSRSRS
Sbjct: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSR---SRKSY----------SRSRSRSRSRSRS 225
Query: 474 RERADN----PGKYKKKSHYYR-------DQRRERSRSYERT 504
+ R+ + P K +K+ R D++R RSRS R+
Sbjct: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Query: 440 GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSR 499
G EI G RK K + ++ +SRSRS SR+RS SR R+ + + +K R + R RSR
Sbjct: 166 GKEING-RKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
Query: 500 SYERTGRR 507
S R+ R
Sbjct: 225 SKSRSVSR 232
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 5/147 (3%)
Query: 281 LQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPK 340
L+ + R+ ++T + K + E + G L + L G KL+E K
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASY--GDLKNAIEKLSGKEINGRKIKLIEGSK 181
Query: 341 EGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSAS 400
S+ S + R ++++ + SRSRS+SR S S P +S
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKS-- 239
Query: 401 PKRRKSDSGSTSGGSKSQSRSRSRSDS 427
++R S S S S S + RSRSRS S
Sbjct: 240 -QKRGSSSRSKSPASVDRQRSRSRSRS 265
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 65.9 bits (159), Expect = 9e-11
Identities = 51/121 (42%), Positives = 64/121 (52%), Gaps = 11/121 (9%)
Query: 352 VKNTKRRLEGAK-KAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGS 410
+KN +L G + + + G + SRSRSRSR +S SRS SRS S R+
Sbjct: 157 LKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSY---- 212
Query: 411 TSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSR 470
S+S+SRSRSRS S R RS + S+ RGS S K P + RSRS SRSR
Sbjct: 213 ----SRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGS--SSRSKSPASVDRQRSRSRSRSR 266
Query: 471 S 471
S
Sbjct: 267 S 267
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/102 (42%), Positives = 52/102 (50%), Gaps = 24/102 (23%)
Query: 414 GSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRS 473
GSK SRSRSRS S R + RS S SRKS SRSRS SRSRSRS
Sbjct: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSR---SRKSY----------SRSRSRSRSRSRS 225
Query: 474 RERADN----PGKYKKKSHYYR-------DQRRERSRSYERT 504
+ R+ + P K +K+ R D++R RSRS R+
Sbjct: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Query: 440 GSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSR 499
G EI G RK K + ++ +SRSRS SR+RS SR R+ + + +K R + R RSR
Sbjct: 166 GKEING-RKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
Query: 500 SYERTGRR 507
S R+ R
Sbjct: 225 SKSRSVSR 232
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 5/147 (3%)
Query: 281 LQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPK 340
L+ + R+ ++T + K + E + G L + L G KL+E K
Sbjct: 124 LKDFMRQAGEVTFADAHRPKLNEGVVEFASY--GDLKNAIEKLSGKEINGRKIKLIEGSK 181
Query: 341 EGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSAS 400
S+ S + R ++++ + SRSRS+SR S S P +S
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKS-- 239
Query: 401 PKRRKSDSGSTSGGSKSQSRSRSRSDS 427
++R S S S S S + RSRSRS S
Sbjct: 240 -QKRGSSSRSKSPASVDRQRSRSRSRS 265
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/163 (35%), Positives = 81/163 (49%), Gaps = 17/163 (10%)
Query: 339 PKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRS 398
PK+ + P P S RL A +A P + P+ E ++ E + R+ R+
Sbjct: 671 PKDIRLPPPMPPS-----ERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYE--FFRAKMRA 723
Query: 399 ASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKP 458
+RRK SG S+S+SRS+SR S R RS+ GS R +S Y +
Sbjct: 724 ---RRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR 780
Query: 459 HKSRSRS-SSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRS 500
+SRSRS SSRSRSRS+ R+ + KS+ +RR RSRS
Sbjct: 781 SRSRSRSRSSRSRSRSQSRS------RSKSYSPGRRRRSRSRS 817
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/98 (36%), Positives = 45/98 (45%), Gaps = 7/98 (7%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSA 399
+E + S PS ++ R ++ S +G SRSRS SR S SRS SRS
Sbjct: 729 QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSG--SYSRSRSRSCSRSYSRSRSRSRSR 786
Query: 400 SPKRRKSDSGSTSGGSKSQS-----RSRSRSDSPPRQA 432
S R + SKS S RSRSRS +PP A
Sbjct: 787 SRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSA 824
>gi|46309849 hypothetical protein LOC57035 [Homo sapiens]
Length = 290
Score = 65.1 bits (157), Expect = 1e-10
Identities = 46/115 (40%), Positives = 60/115 (52%), Gaps = 6/115 (5%)
Query: 400 SPKRRKSDSGSTSGGSK---SQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQ 456
SP+ + S S S SGGS S+SRSRS S S + S+ + R +S+ + Q
Sbjct: 12 SPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQ 71
Query: 457 KPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERT---GRRY 508
+ ++ SRS SRSRSRSR R +Y YYR R RSRS R+ GR Y
Sbjct: 72 RKYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYYRSPSRYRSRSRSRSRSRGRSY 126
Score = 60.1 bits (144), Expect = 5e-09
Identities = 56/152 (36%), Positives = 66/152 (43%), Gaps = 23/152 (15%)
Query: 368 DSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDS 427
DSP G SR SRSR +S+SRS S S R S S S SKS+SRSR R
Sbjct: 17 DSPSTSR-SGGSSRLSSRSRSRSFSRS---SRSHSRVSSRFSSRSRRSKSRSRSRRRHQR 72
Query: 428 PPRQAPRSAPYKGSEIRGSRKSK-----DCKYPQKPHKSRSRSSSRSRSRSRERADNPGK 482
R+ RS S R R + +Y + P + RSRS SRSRSR R
Sbjct: 73 KYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYYRSPSRYRSRSRSRSRSRGRSYCGRAYA 132
Query: 483 YKKKSHYY--------------RDQRRERSRS 500
+ YY RD+ R RSRS
Sbjct: 133 IARGQRYYGFGRTVYPEEHSRWRDRSRTRSRS 164
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/158 (32%), Positives = 75/158 (47%), Gaps = 19/158 (12%)
Query: 332 APKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ-- 389
+P+ +SP + S LS ++ R + ++ + + R S+SRSRSR +
Sbjct: 12 SPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQ 71
Query: 390 --------SYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRS------ 435
SYSRS SRS S + R+ G T +S SR RSRS S R RS
Sbjct: 72 RKYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYYRSPSRYRSRSRSRSRSRGRSYCGRAY 131
Query: 436 APYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRS 473
A +G G ++ YP++ + R RS +RSRSR+
Sbjct: 132 AIARGQRYYGFGRT---VYPEEHSRWRDRSRTRSRSRT 166
Score = 33.1 bits (74), Expect = 0.63
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 456 QKPHKSRSRS------SSRSRSRSRERADNPGKYKKKSHYYRDQR-RERSRSYERTGRRY 508
+K S SRS SSRSRSRS R+ R +R + RSRS R R+Y
Sbjct: 15 EKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQRKY 74
Query: 509 ERDHPGHSRHR 519
R +SR R
Sbjct: 75 RRYSRSYSRSR 85
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 64.7 bits (156), Expect = 2e-10
Identities = 54/133 (40%), Positives = 67/133 (50%), Gaps = 15/133 (11%)
Query: 377 GRESR---SRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAP 433
GRESR RS SR +S SRS SRS S KR K S+S+ R R R S R
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRR---SRSRDRDRRRERSRSRDKR 58
Query: 434 RSAPYKGSEIRGSR-KSKDCKYPQKPHKSRSRSSSRSRSRS-RERADNPGKYKKKSHYYR 491
RS +R SR + +D ++ +SR R SRSRSR R R+ +PG KK+
Sbjct: 59 RSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKT---- 114
Query: 492 DQRRERSRSYERT 504
RSRS E+T
Sbjct: 115 ---ENRSRSKEKT 124
Score = 46.6 bits (109), Expect = 6e-05
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 4/162 (2%)
Query: 325 GTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRS 384
G SG + + +G S +RR + K S + R+ RS
Sbjct: 16 GRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR----SRDRKRLRRS 71
Query: 385 RSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIR 444
RSRE+ SR RS S RR+S S S S+S S + R + G +
Sbjct: 72 RSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSK 131
Query: 445 GSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKK 486
+K KD K +K + + ++ R+R + K++++
Sbjct: 132 EKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREE 173
Score = 37.7 bits (86), Expect = 0.026
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 378 RESRSRSRSR-EQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSA 436
R SRSR R R +S SR RS +R +S S S+S+ R RSRS SP ++ ++
Sbjct: 58 RRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRS-RSRSRGR-RSRSSSPGNKSKKTE 115
Query: 437 PYKGSEIR--GSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQR 494
S+ + G SK+ K K K + + + K K++ +R+++
Sbjct: 116 NRSRSKEKTDGGESSKE-KKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174
Query: 495 RERS 498
R+++
Sbjct: 175 RKKA 178
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 64.7 bits (156), Expect = 2e-10
Identities = 57/181 (31%), Positives = 85/181 (46%), Gaps = 27/181 (14%)
Query: 365 AKADSPVNGLPKGRESRSRSRSREQS------------YSRSPSRSASPKRRKSDSGSTS 412
A +D+ +GL + S R + +EQS YSRS SRS ++RKSD+
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRE-RKRKSDNEGRK 60
Query: 413 GGSKSQSRSRSRSDSPPRQAPRS----------APYKGSEIRGSRKSKDCKYPQKPHKS- 461
S+S+S+ R +S + + + + KG E S ++ + ++ +K KS
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 462 RSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYER---TGRRYERDHPGHSRH 518
R RS SRSRSR R + KK R++++ RSRS ER R ER SR
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
Query: 519 R 519
R
Sbjct: 181 R 181
Score = 64.3 bits (155), Expect = 3e-10
Identities = 59/198 (29%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 338 SPKEGKGSKPSPLSVK--------NTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQ 389
SP K + S +SV + R +K K+D+ +GR+ RSRSRS+E
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN------EGRKHRSRSRSKEG 70
Query: 390 SYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRS-----DSPPRQAPRSAPYKGSEIR 444
R S+ S K+ KS+ + S + R R S D R+ +S+ +
Sbjct: 71 R--RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128
Query: 445 GSRKSKDCKYPQKPHKSRSRSSSR--SRSRSRERADNPGKYKKKSHYYRDQRRERSRSYE 502
SR+ + ++ KSRSRS R SRSRSRER + + +++ R + R RSR
Sbjct: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188
Query: 503 RTGRRYERDHPGHSRHRR 520
RT R R +R
Sbjct: 189 RTRSRSRTRSRSRDRKKR 206
Score = 56.6 bits (135), Expect = 5e-08
Identities = 57/182 (31%), Positives = 79/182 (43%), Gaps = 22/182 (12%)
Query: 340 KEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSA 399
KEG+ + S K K K+ +D KGRE + S + E + R
Sbjct: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSD-------KGRERLNSSENGEDRHKR------ 114
Query: 400 SPKRRKSDSGSTSGGSKSQSR---SRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQ 456
K RKS G + S+S+ R SRSR R RS K S R SR+ K +
Sbjct: 115 --KERKSSRGRSHSRSRSRERRHRSRSRERKKSRS--RSRERKKSRSR-SRERKKSRSRS 169
Query: 457 KPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHS 516
+ K R RS SRSRSR R R + + + +S R +R E+ R + R+ R P
Sbjct: 170 RERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR-DRKKRIEKPRRFSRSLSRTPSPPPFRG 228
Query: 517 RH 518
R+
Sbjct: 229 RN 230
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 6/152 (3%)
Query: 351 SVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRS------PSRSASPKRR 404
S +N + R + ++ + + + RE R RSRSRE+ SRS SRS S +R+
Sbjct: 104 SSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
Query: 405 KSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSR 464
KS S S + +SRSRSRS R RS S R R K ++ + ++ S
Sbjct: 164 KSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
Query: 465 SSSRSRSRSRERADNPGKYKKKSHYYRDQRRE 496
R R+ + + + + +++ ++QR +
Sbjct: 224 PPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,204,447
Number of Sequences: 37866
Number of extensions: 1077754
Number of successful extensions: 21071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 356
Number of HSP's successfully gapped in prelim test: 632
Number of HSP's that attempted gapping in prelim test: 11277
Number of HSP's gapped (non-prelim): 4858
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.