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Search of human proteins with 87116683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
(1989 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 3976 0.0
gi|39930375 enabled homolog isoform b [Homo sapiens] 80 2e-14
gi|56549694 enabled homolog isoform a [Homo sapiens] 79 3e-14
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 65 5e-10
gi|148746195 trichohyalin [Homo sapiens] 65 7e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 9e-10
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 65 9e-10
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 65 9e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 1e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 64 2e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 4e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 4e-09
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 62 4e-09
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 62 4e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 6e-09
gi|195947369 junction-mediating and regulatory protein [Homo sap... 62 7e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 62 7e-09
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 61 1e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 60 2e-08
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 60 2e-08
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 60 2e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 60 2e-08
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 60 2e-08
gi|55741677 SET domain containing 1A [Homo sapiens] 60 3e-08
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 60 3e-08
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 59 4e-08
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 59 4e-08
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 59 4e-08
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 59 5e-08
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 59 6e-08
>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
Length = 1989
Score = 3976 bits (10310), Expect = 0.0
Identities = 1989/1989 (100%), Positives = 1989/1989 (100%)
Query: 1 MATADTPAPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHS 60
MATADTPAPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHS
Sbjct: 1 MATADTPAPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHS 60
Query: 61 ARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMP 120
ARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMP
Sbjct: 61 ARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMP 120
Query: 121 SSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGA 180
SSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGA
Sbjct: 121 SSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGA 180
Query: 181 GSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELE 240
GSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELE
Sbjct: 181 GSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELE 240
Query: 241 CINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFE 300
CINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFE
Sbjct: 241 CINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFE 300
Query: 301 LKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEK 360
LKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEK
Sbjct: 301 LKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEK 360
Query: 361 KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSA 420
KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSA
Sbjct: 361 KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSA 420
Query: 421 KKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSN 480
KKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSN
Sbjct: 421 KKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSN 480
Query: 481 QEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETS 540
QEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETS
Sbjct: 481 QEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETS 540
Query: 541 SPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPP 600
SPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPP
Sbjct: 541 SPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPP 600
Query: 601 LPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLN 660
LPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLN
Sbjct: 601 LPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLN 660
Query: 661 NSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESD 720
NSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESD
Sbjct: 661 NSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESD 720
Query: 721 GEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRL 780
GEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRL
Sbjct: 721 GEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRL 780
Query: 781 LKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILL 840
LKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILL
Sbjct: 781 LKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILL 840
Query: 841 MKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQ 900
MKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQ
Sbjct: 841 MKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQ 900
Query: 901 QRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAE 960
QRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAE
Sbjct: 901 QRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAE 960
Query: 961 LIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQD 1020
LIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQD
Sbjct: 961 LIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQD 1020
Query: 1021 KLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVEKP 1080
KLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVEKP
Sbjct: 1021 KLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVEKP 1080
Query: 1081 ELFLGLKIGELQKLYSKADSLKQLILKTTTGITEKVLHGQEISVDVDFVTAQSKTMEVKP 1140
ELFLGLKIGELQKLYSKADSLKQLILKTTTGITEKVLHGQEISVDVDFVTAQSKTMEVKP
Sbjct: 1081 ELFLGLKIGELQKLYSKADSLKQLILKTTTGITEKVLHGQEISVDVDFVTAQSKTMEVKP 1140
Query: 1141 CPFRPYHSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLTGTCNDDDCQ 1200
CPFRPYHSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLTGTCNDDDCQ
Sbjct: 1141 CPFRPYHSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLTGTCNDDDCQ 1200
Query: 1201 WQHIQDYTLSRKQLFQDILSYNLSLIGCAETSTNEEITASAEKYVEKLFGVNKDRMSMDQ 1260
WQHIQDYTLSRKQLFQDILSYNLSLIGCAETSTNEEITASAEKYVEKLFGVNKDRMSMDQ
Sbjct: 1201 WQHIQDYTLSRKQLFQDILSYNLSLIGCAETSTNEEITASAEKYVEKLFGVNKDRMSMDQ 1260
Query: 1261 MAVLLVSNINESKGHTPPFTTYKDKRKWKPKFWRKPISDNSFSSDEEQSTGPIKYAFQPE 1320
MAVLLVSNINESKGHTPPFTTYKDKRKWKPKFWRKPISDNSFSSDEEQSTGPIKYAFQPE
Sbjct: 1261 MAVLLVSNINESKGHTPPFTTYKDKRKWKPKFWRKPISDNSFSSDEEQSTGPIKYAFQPE 1320
Query: 1321 NQINVPALDTVVTPDDVRYFTNETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGECS 1380
NQINVPALDTVVTPDDVRYFTNETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGECS
Sbjct: 1321 NQINVPALDTVVTPDDVRYFTNETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGECS 1380
Query: 1381 ESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKDEVQEMCETAVEYAPDYQSFWTF 1440
ESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKDEVQEMCETAVEYAPDYQSFWTF
Sbjct: 1381 ESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKDEVQEMCETAVEYAPDYQSFWTF 1440
Query: 1441 LHLESTFEEKDYVCERMLEFLMGAAKQETSNILSFQLLEALLFRVQLHIFTGRCQSALAI 1500
LHLESTFEEKDYVCERMLEFLMGAAKQETSNILSFQLLEALLFRVQLHIFTGRCQSALAI
Sbjct: 1441 LHLESTFEEKDYVCERMLEFLMGAAKQETSNILSFQLLEALLFRVQLHIFTGRCQSALAI 1500
Query: 1501 LQNALKSANDGIVAEYLKTSDRCLAWLAYIHLIEFNILPSKFYDPSNDNPSRIVNTESFV 1560
LQNALKSANDGIVAEYLKTSDRCLAWLAYIHLIEFNILPSKFYDPSNDNPSRIVNTESFV
Sbjct: 1501 LQNALKSANDGIVAEYLKTSDRCLAWLAYIHLIEFNILPSKFYDPSNDNPSRIVNTESFV 1560
Query: 1561 MPWQAVQDVKTNPDMLLAVFEDAVKACTDESLAVEERIEACLPLYTNMIALHQLLERYEA 1620
MPWQAVQDVKTNPDMLLAVFEDAVKACTDESLAVEERIEACLPLYTNMIALHQLLERYEA
Sbjct: 1561 MPWQAVQDVKTNPDMLLAVFEDAVKACTDESLAVEERIEACLPLYTNMIALHQLLERYEA 1620
Query: 1621 AMELCKSLLESCPINCQLLEALVALYLQTNQHDKARAVWLTAFEKNPQNAEVFYHMCKFF 1680
AMELCKSLLESCPINCQLLEALVALYLQTNQHDKARAVWLTAFEKNPQNAEVFYHMCKFF
Sbjct: 1621 AMELCKSLLESCPINCQLLEALVALYLQTNQHDKARAVWLTAFEKNPQNAEVFYHMCKFF 1680
Query: 1681 ILQNRGDNLLPFLRKFIASFFKPGFEKYNNLDLFRYLLNIPGPIDIPSRLCKGNFDDDMF 1740
ILQNRGDNLLPFLRKFIASFFKPGFEKYNNLDLFRYLLNIPGPIDIPSRLCKGNFDDDMF
Sbjct: 1681 ILQNRGDNLLPFLRKFIASFFKPGFEKYNNLDLFRYLLNIPGPIDIPSRLCKGNFDDDMF 1740
Query: 1741 NHQVPYLWLIYCLCHPLQSSIKETVEAYEAALGVAMRCDIVQKIWMDYLVFANNRAAGSR 1800
NHQVPYLWLIYCLCHPLQSSIKETVEAYEAALGVAMRCDIVQKIWMDYLVFANNRAAGSR
Sbjct: 1741 NHQVPYLWLIYCLCHPLQSSIKETVEAYEAALGVAMRCDIVQKIWMDYLVFANNRAAGSR 1800
Query: 1801 NKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTL 1860
NKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTL
Sbjct: 1801 NKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTL 1860
Query: 1861 ERFCSVMPANSGLALRLLQHEWEESNVQILKLQAKMFTYNIPTCLATWKIAIAAEIVLKG 1920
ERFCSVMPANSGLALRLLQHEWEESNVQILKLQAKMFTYNIPTCLATWKIAIAAEIVLKG
Sbjct: 1861 ERFCSVMPANSGLALRLLQHEWEESNVQILKLQAKMFTYNIPTCLATWKIAIAAEIVLKG 1920
Query: 1921 QREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLN 1980
QREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLN
Sbjct: 1921 QREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLN 1980
Query: 1981 SNKTESKNH 1989
SNKTESKNH
Sbjct: 1981 SNKTESKNH 1989
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 80.5 bits (197), Expect = 2e-14
Identities = 111/479 (23%), Positives = 191/479 (39%), Gaps = 61/479 (12%)
Query: 340 LQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKE 399
L +E T S + ++ + G +EEL E+Q R L Q K+ +++ + + +E
Sbjct: 111 LNSQETGPTLPRQNSQLPAQVQNGPSQEEL-EIQRRQLQEQQRQKELERERLERERMERE 169
Query: 400 KLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQ 459
+L + + +++++ +++ ++ R+++ + ++L++Q+ ERQ+ D+ +Q
Sbjct: 170 RLERERLERERLERERLEQ--EQLERERQERERQERLERQERLERQERLERQERLDRERQ 227
Query: 460 AEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSG 519
E + R+R E + + R ++EQ R +RR S ++ + L+ DS
Sbjct: 228 --ERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSS 285
Query: 520 GGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSS--L 577
E + S+ PA +P Q LG +P P LPP P +S L
Sbjct: 286 AS--------EPGLQAASQ---PAETPSQQGIV----LGPLAPPPPPPLPPGPAQASVAL 330
Query: 578 PPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPP----------FADEEEEEEML 627
PP P S P PP PP PPLP + P PP PP A E+ L
Sbjct: 331 PPPPGPPPPPPLPSTGPPPPPPP-PPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPL 389
Query: 628 LREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSIVSINTVSQP----RI 683
L ++A + K S P S + + +N+ S R
Sbjct: 390 --TGLAAAIAGAKLRKVSRMEDTSFP--------------SGGNAIGVNSASSKTDTGRG 433
Query: 684 QNPKFHRGPRLPRTVISL------PKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESM 737
P G L + +L K + +D D E S S E
Sbjct: 434 NGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPT 493
Query: 738 IKEARRTAEQASKPKVPPKSEKENDPLRTPEAL-PEEKKIEYRLLKEEIANREKQRLIK 795
K RT + K P S ++ PL P A + + ++Y LK++I + ++ L K
Sbjct: 494 RKPWERT-NTMNGSKSPVISRPKSTPLSQPSANGVQTEGLDYDRLKQDILDEMRKELTK 551
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 79.3 bits (194), Expect = 3e-14
Identities = 72/279 (25%), Positives = 128/279 (45%), Gaps = 23/279 (8%)
Query: 340 LQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKE 399
L +E T S + ++ + G +EEL E+Q R L Q K+ +++ + + +E
Sbjct: 111 LNSQETGPTLPRQNSQLPAQVQNGPSQEEL-EIQRRQLQEQQRQKELERERLERERMERE 169
Query: 400 KLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQ 459
+L + + +++++ +++ ++ R+++ + ++L++Q+ ERQ+ D+ +Q
Sbjct: 170 RLERERLERERLERERLEQ--EQLERERQERERQERLERQERLERQERLERQERLDRERQ 227
Query: 460 AEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSG 519
E + R+R E + + R ++EQ R +RR S ++ + L+ DS
Sbjct: 228 --ERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSS 285
Query: 520 GGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSS--L 577
E + S+ PA +P Q LG +P P LPP P +S L
Sbjct: 286 AS--------EPGLQAASQ---PAETPSQQGIV----LGPLAPPPPPPLPPGPAQASVAL 330
Query: 578 PPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPP 616
PP P S P PP PP PPLP + P PP PP
Sbjct: 331 PPPPGPPPPPPLPSTGPPPPPPP-PPLPNQVPPPPPPPP 368
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 65.5 bits (158), Expect = 5e-10
Identities = 192/1016 (18%), Positives = 353/1016 (34%), Gaps = 103/1016 (10%)
Query: 7 PAPASSGLSPKEEG--------ELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPP 58
PAP++S + G G S +++ Q R S ++SG +
Sbjct: 113 PAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSE 172
Query: 59 HSARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVR 118
HS S G + SS +SS R+ H+ E H R S P++P + R
Sbjct: 173 HSKSRSSSPGKPQAVSSLNSSHS--RSHGNDHHSKE--HQRSKS---PRDPDANWDSPSR 225
Query: 119 MPSSSLSESSPR--PSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPL 176
+P SS S+ PS +S+ L + RP G+ P L
Sbjct: 226 VPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRP---------------MDGQESMEPKL 270
Query: 177 GGGAGSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNE-NCVEETFEDLLLKYKQ- 234
S S S E P K+ + + PS+ + S+ + +CV+E +++ +
Sbjct: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPP 330
Query: 235 -IQLELECINKDEKLALSSKE---------ENVQEDP-KTLNFEDQTSTDNVSITKDSSK 283
+ C + K +KE E + +P KT N S + SS+
Sbjct: 331 LTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSE 390
Query: 284 EVAPE---EKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGL 340
+ E +KT ++ +P + D +R S SD+ S
Sbjct: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHN-SEGADNSRDDSSSHSGSESSSGSDSESESSSS 449
Query: 341 QDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEK 400
+ ++ S + + L+++ ++ S+ Q KE +E+
Sbjct: 450 DSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ 509
Query: 401 LTKTKTVQ----QKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKE-ED 455
T ++ ++T +K + ++ +Q++ A Q+ +K+ +
Sbjct: 510 GTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK 569
Query: 456 QRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQP 515
K A EE R + E DL++ G ++ + K S R + +K+
Sbjct: 570 AEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKK 629
Query: 516 TDSGGGIYQYDNYEEVAMDT---DSETSSPAPSPVQPPFFSECSLGYFSPAP-------- 564
S Q + E + DT DS+ S P Q P + E + P+
Sbjct: 630 YKSTSKSSQ-KSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFF 688
Query: 565 -SLSLPPPPQVSSLPPLSQP---YVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADE 620
P + L PLS+P Y + + L L +P P E P+ K
Sbjct: 689 RQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKH 748
Query: 621 EEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSIVSINTVSQ 680
E + E++ K + + +S S P N++ P SN + +
Sbjct: 749 TREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE 808
Query: 681 -PRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIK 739
+ +P + P+T +H S T++ S +S ++K T+ S K
Sbjct: 809 KDLLPSPAGPVPSKDPKT-----EHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSK 863
Query: 740 EAR---RTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKS 796
+ + +T+ + + K S N P P L K +L+ ++ L ++
Sbjct: 864 QKKTEGKTSSSSKEVKEKAPSSSSNCPPSAP-TLDSSKPRRTKLVFDDRNYSADHYLQEA 922
Query: 797 DQLKTSSSSPA----------NSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESV 846
+LK ++ + + ++ V G Q + + + + L+K
Sbjct: 923 KKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMK 982
Query: 847 LKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIK 906
LKN + +A + +LT E +L + LKK + ++ T+
Sbjct: 983 LKNYLAPDATAADK---------RLTVLCLRCESLLYLRLFKLKK----ENALKYSKTLT 1029
Query: 907 KALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELI 962
+ L Y A + + SK +G + P S S+ S+ I
Sbjct: 1030 EHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTI 1085
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.1 bits (157), Expect = 7e-10
Identities = 71/306 (23%), Positives = 144/306 (47%), Gaps = 49/306 (16%)
Query: 222 EETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDS 281
EE E + ++ + EL+ + ++E+L + + +QE+ ED + +D
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE------ED-------GLQEDQ 860
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQ 341
+ + E++ K E + R++ TL AKP +L+ Q LQ
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLY------------AKP-ALQEQLRKEQQLLQ 907
Query: 342 DKEQNLTRRISTSDILSE-KKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESK-- 398
++E+ L R E ++ +EE+L + + +LL + ++ Q++E+Q K+ K
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 399 ----EKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTK----AWKKLQQQKEQER 450
+ L + +++ + K +++ +Q LR+++ K W++ Q +K+ E
Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER-QYRKKDEL 1026
Query: 451 QKEEDQRKQAEEEERR--KREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLR 508
Q+EE+Q + E E+RR +RE + R+ +L +EEQ L+G +R +R + +L
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ------LLGEERETRRRQ---ELE 1077
Query: 509 RSLDKQ 514
R K+
Sbjct: 1078 RQYRKE 1083
Score = 60.1 bits (144), Expect = 2e-08
Identities = 37/153 (24%), Positives = 90/153 (58%), Gaps = 7/153 (4%)
Query: 359 EKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH 418
+++L E+EE+L +L+ + L + ++ QQ+ + ++ + K + + QQ+ + +
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 419 SAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE--EERRKREEEIRKIR 476
++ +Q R+Q+ + ++L++++E+ER++++ +R+Q EE E++ +RE+++R+ +
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 477 DLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRR 509
L +E+Q R +L RR + + LRR
Sbjct: 388 QL-RREQQLRREQQL----RREQQLRREQQLRR 415
Score = 59.7 bits (143), Expect = 3e-08
Identities = 60/283 (21%), Positives = 130/283 (45%), Gaps = 20/283 (7%)
Query: 213 YSSKNENCVEETFEDLLLKYKQIQLELECI--------NKDEKLALSSKEENVQEDPKTL 264
Y EN ED L+ +Q Q +L+ + + E+ ++ + E+ + L
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ-L 1299
Query: 265 NFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELK-PLRQKLTLPGDKNRLKKVKDG 323
E+Q K++ EE+ + + Q + K ++L ++ L++ +
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 324 AKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSAS 383
K + + + ++EQ L R+ L E++ +E E QLR Q
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER--EQQLR----QDRD 1413
Query: 384 KKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQ 443
+K++++EQQ+ ++ +++ K + +Q+V+ + + +Q ++ + + LQ
Sbjct: 1414 RKFREEEQQLSRQERDR--KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471
Query: 444 QQKEQERQKEEDQRKQAEEEERRKREEEIRKIR--DLSNQEEQ 484
+++EQ+ ++E RK EEE++ +R+E RK R +L +QE +
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Score = 58.9 bits (141), Expect = 5e-08
Identities = 64/346 (18%), Positives = 154/346 (44%), Gaps = 38/346 (10%)
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEK 247
Q R+ ++ + G S KQ + + + ++ L + +Q E E +E+
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDR---QRRDEELWRQRQEWQEREERRAEEE 191
Query: 248 LALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKT--QVKTFQAFELKPLR 305
S K +E P E+Q + + +E +++ Q + FQ E K R
Sbjct: 192 QLQSCKGHETEEFPD----EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR 247
Query: 306 QKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGED 365
++ T+ L+K ++ L+ + + LQ++E+ L R++ ++ E++ E
Sbjct: 248 KRETV------LRKEEE-----KLQEEEPQRQRELQEEEEQL-RKLERQELRRERQEEEQ 295
Query: 366 EEELSELQLRLLALQSASKKWQQ----------------KEQQVMKESKEKL-TKTKTVQ 408
+++ + +L Q ++ QQ +EQQ+ +E +E+ + + Q
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Query: 409 QKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKR 468
++ + + ++ +Q R+QQ + ++L+++++ R+++ + +Q E++ +R
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 469 EEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
E+++R+ + L ++E+ K +R R K + R L ++
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Score = 58.2 bits (139), Expect = 8e-08
Identities = 44/189 (23%), Positives = 100/189 (52%), Gaps = 14/189 (7%)
Query: 329 LKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQ 388
LK + + + + +EQ L R + E++L EEE LQ RL + Q ++ ++
Sbjct: 489 LKLEEEERREQQERREQQLRRE---QEERREQRLKRQEEE-ERLQQRLRSEQQLRREQEE 544
Query: 389 KEQQVMKESKEKLTKTKTVQQKVK---TSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQ 445
+ +Q++K +EK + + +Q++K + K+ +Q L+++Q + ++ ++
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 446 KEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDP 505
+E ER ++E++R E+ +R+ EE R+ + L ++E++ R +L RR + + +
Sbjct: 605 EEVERLEQEERR---EQRLKREEPEEERRQQLLKSEEQEERRQQQL----RREQQERREQ 657
Query: 506 DLRRSLDKQ 514
L+R +++
Sbjct: 658 RLKREEEEE 666
Score = 57.4 bits (137), Expect = 1e-07
Identities = 48/226 (21%), Positives = 105/226 (46%), Gaps = 21/226 (9%)
Query: 335 DSSQGLQDKEQNLTRRISTSDILSEK--KLGEDEEELSELQLRLLALQSASKKWQQKEQQ 392
+ + + EQ L R+ + E+ K EDE+ L E + + L Q +K+ ++E Q
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 393 VMKESKEKLTK----------TKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKL 442
+ ++ +E+ + + +Q+ + + + +Q LR+Q+ + K L
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER-KFL 1710
Query: 443 QQQKEQERQ------KEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKR 496
Q++++ RQ +EE+Q +Q E+E+ +R+E RKI L ++ + R + + +
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI--LEEEQLRPEREEQQLRRQE 1768
Query: 497 RSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSP 542
R R + LR+ ++Q S ++ E++ + + + P
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Score = 56.6 bits (135), Expect = 2e-07
Identities = 60/327 (18%), Positives = 148/327 (45%), Gaps = 28/327 (8%)
Query: 205 RSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV---QEDP 261
+ R+ S + + + E E+ K+ + E + ++E+ L +EE QE
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREE-----KRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 262 KTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVK 321
+ E+ + + + + +E+ + + +L+ ++ L D++R K +
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR--KFR 1417
Query: 322 DGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSE---------KKLGEDEEELSEL 372
+ + LS + + + +++EQ + R+ L E +K E+E+ L E
Sbjct: 1418 EEEQQLSRQ----ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 373 QLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQA-- 430
+ + L Q +K+ ++EQQ+ ++ +++ + + ++ + +++ +Q
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 431 LRKQQTKAWKKLQQQKEQERQ---KEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
L+++Q ++ QQ+ Q+R +EE+Q +Q EE++ R+E RK R + + +
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 488 FMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
K + +++ R + LR+ D++
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Score = 55.8 bits (133), Expect = 4e-07
Identities = 60/287 (20%), Positives = 136/287 (47%), Gaps = 28/287 (9%)
Query: 241 CINKDEKLALSSKEENVQE-DPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAF 299
C K+ L +EE+ + +P+ E++ ++ +E+A E+ K +
Sbjct: 103 CDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 300 ELKPLRQKLTLPGDKNRLKKVKDG-AKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILS 358
+ R+ L + ++ ++ A+ L+S ++ D+EQ L RR ++L
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ-LRRR----ELLE 217
Query: 359 EKKLGEDE---------------EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTK 403
++ G +E EE E + R L+ +K Q++E Q +E +E+ +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Query: 404 TKTVQ-QKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
+ ++ Q+++ + ++ +Q LR++Q + ++ QQ++ +E+Q+ +Q+++ E
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE-RREQQEERREQQERREQQEERRE 336
Query: 463 EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRR 509
++ R RE+E R+ + L ++E+ R +L +R + + LRR
Sbjct: 337 QQLR-REQEERREQQLRREQEEERREQQL---RREQEEERREQQLRR 379
Score = 55.1 bits (131), Expect = 7e-07
Identities = 63/302 (20%), Positives = 135/302 (44%), Gaps = 43/302 (14%)
Query: 233 KQIQLELECINKDE--KLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEK 290
+Q+Q E E + ++E K +E ++D K E+Q + + +E E+
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 291 TQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRR 350
+++ + L+ R+K + + +K + LQ +E+ L R
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDE-----------------LQQEEEQLLRE 1036
Query: 351 ISTSDILSEKKLG-EDEEELSELQLRLLALQSASKKWQQ------KEQQVMKESKEKLTK 403
L E++ +EEEL + + +LL + +++ Q+ KE+++ +E ++ L +
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 404 TKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEE 463
+++ + + +++ +Q LR+++ K ++++E ERQ E++ Q +EE
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREK-----RRRQELERQYREEEEVQ-QEE 1150
Query: 464 ERRKREE-----------EIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLD 512
E+ REE + R+ +L +EEQ R + + R R + +L+R
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Query: 513 KQ 514
KQ
Sbjct: 1211 KQ 1212
Score = 54.7 bits (130), Expect = 9e-07
Identities = 62/303 (20%), Positives = 139/303 (45%), Gaps = 23/303 (7%)
Query: 209 RKQNYSSKNENCVEETFEDLLLKYKQIQLELEC---INKDEKLALSSKEENVQEDPKTLN 265
++Q + E +++ E LL + ++ + E KD+KL +E+ + E+P+
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ-QKEEQLLGEEPEKRR 982
Query: 266 FEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAK 325
+++ +E E+ + + Q +E + R+K L ++ +L + + +
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWE-RQYRKKDELQQEEEQLLREEREKR 1041
Query: 326 PLSLKSDTTDSSQGLQDKEQNL------TRRISTSD--ILSEKKLGEDEEELSELQLRLL 377
L + + LQ +E+ L TRR + E++L ++EE+L +
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 378 ALQSASKKW------QQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQAL 431
Q ++ QQ+E+Q+++E +EK + + +Q + +++ +
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 432 RKQ----QTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
R+Q Q + ++LQQ++EQ ++E+++R+Q E + R+ EE R+ R ++E
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 488 FMK 490
+K
Sbjct: 1222 DLK 1224
Score = 54.3 bits (129), Expect = 1e-06
Identities = 66/331 (19%), Positives = 146/331 (44%), Gaps = 39/331 (11%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E L + +Q++ E + + E+ K E + + + L E + D + +++ +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR-LKREQEERRDWLKREEETERHE 468
Query: 286 APEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQ 345
K Q+K Q E + + L L ++ R ++ + + + + + Q++E+
Sbjct: 469 QERRKQQLKRDQEEERR--ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Query: 346 NLTRRISTSDILS-------EKKLGEDEEELSELQLRLLAL---------QSASKKWQQK 389
L +R+ + L E+ L +EE+ E + R L Q ++ +++
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586
Query: 390 EQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQ----TKAWKKLQQQ 445
+Q++ +E +E+L + ++ + + +++ + R+QQ + ++ QQQ
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 446 KEQERQKEEDQRKQAEEEERR-----KRE-EEIRKIRDLSNQEEQYNRFMKLVGGKRRSR 499
+E+Q+ +QR + EEEE R KRE EE R+ ++L+ +E++ + R R
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE----------QARER 696
Query: 500 SKSSDPDLRRSLDKQPTDSGGGIYQYDNYEE 530
KS P + L+ + +Y +E
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Score = 53.9 bits (128), Expect = 2e-06
Identities = 44/188 (23%), Positives = 95/188 (50%), Gaps = 24/188 (12%)
Query: 340 LQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKE 399
L ++E+ RR + E + E+EE+L + +++ Q++E + ++ +
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQR--------RERAQQLQEEEDGLQEDQER 862
Query: 400 KLTKTKTVQQKVKTSTKTHSAKKVSTT-AKQALRKQQTKAWKKLQQQKEQERQKEEDQRK 458
+ ++ + QK + + ++ T AK AL++Q K ++L Q++E+E Q+EE +++
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE-QQLLQEEEEELQREEREKR 921
Query: 459 QAEEEERRKREE------------EIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPD 506
+ +E+ER+ REE E R+ R +E QY + KL ++ + +P+
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL--QQKEEQLLGEEPE 979
Query: 507 LRRSLDKQ 514
RR +++
Sbjct: 980 KRRRQERE 987
Score = 52.4 bits (124), Expect = 4e-06
Identities = 68/361 (18%), Positives = 152/361 (42%), Gaps = 40/361 (11%)
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETF----EDLLLKY---KQIQLELE 240
+ +R+ ++ + R K+ + C EE E+ LL+ K+ + ELE
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 241 CINKDEKLALSSKEENVQEDP---------KTLNFEDQTSTDNVSITKDSSKEVAPEEKT 291
++E+ +E+ ++E+P + E++ + + ++ ++ E +
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 292 QVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTT-----DSSQGLQDKEQN 346
Q + + + + +Q+ ++ LK + K +++ + ++ Q Q ++
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 347 LTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKT 406
L R S D+ + LGE +E E + R Q + + ++EQ +E KE + +
Sbjct: 1258 LRDRQSQQDL--QHLLGEQQERDREQERR--RWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 407 VQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQ----------KEQERQKEEDQ 456
Q++ + + K+ + R+++ ++ +Q +E+E + +E
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 457 RKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPT 516
RK EEE+R +R+E RK +EEQ R + R+ R + + + L +Q
Sbjct: 1374 RKFLEEEQRLRRQERERKFL----KEEQQLRCQEREQQLRQDRDRKFREE-EQQLSRQER 1428
Query: 517 D 517
D
Sbjct: 1429 D 1429
Score = 51.6 bits (122), Expect = 8e-06
Identities = 58/338 (17%), Positives = 147/338 (43%), Gaps = 19/338 (5%)
Query: 191 REPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLAL 250
RE ++ K P R++ + E + ++L + ++ + + + + ++++L
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 251 SSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKP--LRQKL 308
+EE ++ + +++ + +E + Q++ Q E + LR++
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 309 TLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRIST---SDILSEKKLGED 365
+ +L++ + + L+ + + +EQ L R + E++L +
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 366 EEELSELQL--------RLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKT 417
+EE Q RL Q + W ++E++ + +E+ + Q+ + +
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 418 HSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQ-AEEEERRKREEEIRKIR 476
++ +Q R+QQ + ++ ++++ +RQ+EE++ +Q E++ +RE+E R+ +
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 477 DLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
L +EE+ +L +R R K + R L K+
Sbjct: 549 LLKREEEK-----RLEQERREQRLKREQEERRDQLLKR 581
Score = 50.4 bits (119), Expect = 2e-05
Identities = 49/246 (19%), Positives = 115/246 (46%), Gaps = 38/246 (15%)
Query: 231 KYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEK 290
K+++ + +L ++ K ++ QE + E+Q + +++ +E ++
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ-------LRQETEQEQLRRQE 1744
Query: 291 TQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRR 350
K + +L+P R++ L + K + Q Q++E+ R
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRK--------------FREEEQLRQEREEQQLRS 1790
Query: 351 ISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQK 410
S++K E+E+ E + + L Q K++ +E+Q+ E +E+ + + +Q
Sbjct: 1791 QE-----SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ- 1844
Query: 411 VKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQ---KEEDQRKQAEEEERRK 467
+ A++ T +++ R++Q + W++ +Q++ QER+ +EE R+Q +EE+R +
Sbjct: 1845 -------YRAEEQFATQEKSRREEQ-ELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
Query: 468 REEEIR 473
+ EI+
Sbjct: 1897 QVGEIK 1902
Score = 49.7 bits (117), Expect = 3e-05
Identities = 54/310 (17%), Positives = 143/310 (46%), Gaps = 29/310 (9%)
Query: 231 KYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEK 290
+ ++ + E + + ++++L +E+ +++D + F ++ +++ EE+
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQD-RDRKFREEEQ----QLSRQERDRKFREEE 1436
Query: 291 TQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKE-QNLTR 349
QV+ Q E K L ++ L +++R + + Q LQ++E Q L R
Sbjct: 1437 QQVRR-QERERKFLEEEQQLRQERHRKFR---------------EEEQLLQEREEQQLHR 1480
Query: 350 RISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQ 409
+ L E++ +E + + + L Q +K+ ++EQQ+ ++ +++ K +Q+
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR----KFLQE 1536
Query: 410 KVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKE---EDQRKQAEEEERR 466
+ + + ++ ++ ++Q + ++ QQ QER ++ E+Q+ + +E+ER+
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 467 KREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYD 526
E+E + R Q+ + R K ++ + + R+ D++ + + + +
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 527 NYEEVAMDTD 536
+++ D D
Sbjct: 1657 REQQLRHDRD 1666
Score = 48.1 bits (113), Expect = 8e-05
Identities = 33/133 (24%), Positives = 74/133 (55%), Gaps = 10/133 (7%)
Query: 359 EKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH 418
++K E+E+ E + + L Q + +K+++ E+Q+ +E +E+ + + K + +
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 419 SAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRD- 477
++ +Q LR+++ + ++ +Q QE+ + E+Q EEE++R++E E RK+R+
Sbjct: 1829 QLEE----QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE-RKLREE 1883
Query: 478 ---LSNQEEQYNR 487
+EEQ +R
Sbjct: 1884 HIRRQQKEEQRHR 1896
Score = 47.4 bits (111), Expect = 1e-04
Identities = 63/324 (19%), Positives = 140/324 (43%), Gaps = 18/324 (5%)
Query: 209 RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSS-KEENVQEDPKTLNFE 267
R+Q + E +E+ + LK +Q + + + ++E+ K E + + L E
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 268 DQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNR----LKKVKDG 323
+ + + K PEE+ + + ++ E + RQ+ + R LK+ ++
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 324 AK---PLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEEL--SELQLRLLA 378
+ L + + Q L ++EQ R S I + E E + S++ R
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 379 LQSASKKWQQKEQQVMKESK------EKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALR 432
+ ++ +Q+E++ +ES+ E+ + + +++ + T A++ S +Q L
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 433 KQQTKAWKKLQQQKEQERQKEEDQ--RKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMK 490
+ ++ +Q + +ERQ+ E + ++ E+E+RR++ E K +EEQ R +
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER 845
Query: 491 LVGGKRRSRSKSSDPDLRRSLDKQ 514
+ D + RRS +++
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQR 869
Score = 42.7 bits (99), Expect = 0.004
Identities = 50/283 (17%), Positives = 128/283 (45%), Gaps = 23/283 (8%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E LL + ++ QL + +D K +E+ ++ + F +Q K +E
Sbjct: 1467 EQLLQEREEQQLHRQ--ERDRKFL--EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 286 APEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQ 345
+ + + F E + RQ+ ++R +K ++ + + + S Q K +
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 346 NLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTK 405
+++ + E+K EDE++L + + Q +K+++ EQ + + +++L + +
Sbjct: 1583 LEEQKVRRQE--QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 406 TVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER 465
++ ++ + LR+Q+ + ++L+ ++++ ++EE ++ EE++
Sbjct: 1641 RDRKFLEEEPQ--------------LRRQERE--QQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 466 RKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLR 508
R++E + RK R+ Q + R K + +++ R + + R
Sbjct: 1685 RRQERD-RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Score = 40.4 bits (93), Expect = 0.017
Identities = 58/306 (18%), Positives = 131/306 (42%), Gaps = 52/306 (16%)
Query: 216 KNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNV 275
K E EE + LL +Q + + + ++++ +E+ ++ + + E + ++
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQ---ERREQRLKREEEEERLEQRLKREHE 677
Query: 276 SITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTD 335
++ +E+A EE+ Q + + + +L D + K K +
Sbjct: 678 EERRE--QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--------E 727
Query: 336 SSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQ-SASKKWQQKEQQV- 393
+ Q++E+ RR S E++ ++E E Q R Q A +K ++ Q++
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQE--EEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 394 ----MKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQ--------QTKAWKK 441
++E +E+ + + QQ+ + K+ ++ K+ Q + ++
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER 845
Query: 442 LQQ--------QKEQERQKEEDQRKQAE-----EEERRKR----------EEEIRKIRDL 478
QQ Q++QER++ ++QR+ + EEER++R +E++RK + L
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 479 SNQEEQ 484
+EE+
Sbjct: 906 LQEEEE 911
Score = 40.0 bits (92), Expect = 0.023
Identities = 65/329 (19%), Positives = 138/329 (41%), Gaps = 54/329 (16%)
Query: 746 EQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLI--KSDQLKTSS 803
+Q + +P + EKE R + EK++++ +E++ RE+ + + + D L+
Sbjct: 804 QQREQRFLPEEEEKEQ---RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 804 SSPANSDVEIDGIGRIAMVTKQ---------VTDAESKLKKHRILLMKDESVLKNLVQQE 854
+ + D R + ++ + +L+K + LL ++E L+ +++
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 855 AKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYG 914
+++E R + EQLQ E+ L L++ +E+ R ++ +K L+
Sbjct: 921 RRRQEQERQYREE-----EQLQQEEEQL------LREEREKRRRQERERQYRKDKKLQQK 969
Query: 915 EELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEY 974
EE + E +R+ + ++ + ++ + + + EKRR Q+ E
Sbjct: 970 EEQLLGE---EPEKRRRQEREKKYREEEELQQEEEQLLREER--------EKRRRQEWER 1018
Query: 975 EYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVDDE 1034
+Y K + +E L +E++ + E E ++ + EE ++E
Sbjct: 1019 QYRKKDELQQEEEQL-LREEREKRRLQERERQYR----------------EEEELQQEEE 1061
Query: 1035 ILSGSSRE-RRRSFLESNYFTKPNLKHTD 1062
L G RE RRR LE Y + L+ +
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEE 1090
Score = 39.3 bits (90), Expect = 0.039
Identities = 62/331 (18%), Positives = 138/331 (41%), Gaps = 26/331 (7%)
Query: 735 ESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLI 794
E ++ R +Q + + + E+E + EE++ E +L +E+ R +Q+L
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 795 KSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQE 854
+ QL+ + + + +Q E +L++ + L + + + ++
Sbjct: 379 REQQLRREQQLRREQQLRREQ----QLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 855 AKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYG 914
+K E R + + E+ ++ R ++ ++Q+ R Q+ ++ L L+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 915 E----------ELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAM 964
E +L R + ++ KR+ E++R + +R + + +L+
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERL--QQRLRSEQQLRREQEERREQLLKR 552
Query: 965 -EKRRLQKLEYEYALK-IQKLKEARALKAKE---QQNISPVVEEEPEFSLPQPSLHDLTQ 1019
E++RL++ E LK Q+ + + LK +E QQ + EE E L + + L Q
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 1020 D-----KLTLDTEENDVDDEILSGSSRERRR 1045
+ +L + E + ++L +E RR
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERR 643
Score = 38.5 bits (88), Expect = 0.066
Identities = 32/162 (19%), Positives = 75/162 (46%), Gaps = 12/162 (7%)
Query: 359 EKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH 418
E+K E+E+ E + L Q +K + E+Q+ E +E+ + + +K + +
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILE-EEQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 419 SAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEE------DQRKQAEEEERRKREEEI 472
++ +Q LR Q++ + ++Q QER++++ D + + EEE+ + E+E
Sbjct: 1781 QERE-----EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 473 RKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
R ++ Q +F +R + + + +R +++
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Score = 37.4 bits (85), Expect = 0.15
Identities = 76/384 (19%), Positives = 152/384 (39%), Gaps = 50/384 (13%)
Query: 735 ESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLI 794
E + +R + + ++ + ++E++ R + L EE++ E+ R K R+
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ-------EQARERIKSRIP 702
Query: 795 KSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQE 854
K S + S V + +Q + + + ++ + ++E + ++E
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 855 AK-----------KKESVRNAEAKITKLTEQ----LQATEKILNVNRMFLKKLQEQIHRV 899
+ K E R + L EQ L+A E+ R ++ +++ R
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Query: 900 QQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSA 959
Q+R K+ L+ E+L R + + + L++D+ R S +K
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ------ERRRSQEQRRDQKWRW 876
Query: 960 ELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQ 1019
+L KRR L + AL+ Q KE + L+ +E++ + EE E Q Q
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE----LQREEREKRRRQ------EQ 926
Query: 1020 DKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVEK 1079
++ + E+ ++E L RE+RR + K +K+ K + E+
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK---------DKKLQQKEEQLLGEE 977
Query: 1080 PELFLGLKIGELQKLYSKADSLKQ 1103
PE + E +K Y + + L+Q
Sbjct: 978 PE---KRRRQEREKKYREEEELQQ 998
Score = 36.2 bits (82), Expect = 0.33
Identities = 65/341 (19%), Positives = 138/341 (40%), Gaps = 30/341 (8%)
Query: 735 ESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKI--EYRLLKEEIANREKQR 792
E ++ + + + + + E+ LR + L E+++ E +L +E+ RE+Q
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ- 406
Query: 793 LIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKH----RILLMKDESVLK 848
L + QL+ + + + E +LK+ R L ++E +
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 849 NLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKA 908
+ +QE +K++ R+ E + + +L+ E+ R + +EQ R +QR+ ++
Sbjct: 467 H--EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 909 -----LTLKYGEELARAKAVASKEIGKR----KLEQDR----FGPNKMMRLDSSPVSSPR 955
L+ ++L R + +++ KR +LEQ+R + R D
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 956 KHSAELIAMEKRRL-QKLEYEYALKI-------QKLKEARALKAKEQQNISPVVEEEPEF 1007
+ L ++ RL Q+L+ E ++ Q+LK + + QQ + +EE
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 1008 SLPQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFL 1048
+ + + +L + EE ++ + ERR L
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
Score = 34.7 bits (78), Expect = 0.96
Identities = 57/305 (18%), Positives = 125/305 (40%), Gaps = 29/305 (9%)
Query: 768 EALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVT 827
E P+E+++ R L E R K R K Q + + E + R ++ K+
Sbjct: 202 EEFPDEEQLRRRELLEL---RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 828 DAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRM 887
+ + + + L ++E L+ L +QE +++ + E + +L + Q K R
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRER--QEEEQQQQRLRREQQLRRKQEEERRE 316
Query: 888 FLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLD 947
++ +EQ R +Q+ ++ L+ +E R + + ++ +R+ +Q R
Sbjct: 317 QQEERREQQERREQQEE-RREQQLRREQEERREQQLRREQEEERREQQLR---------- 365
Query: 948 SSPVSSPRKHSAELIAMEKRRLQKLEYEYAL-KIQKLKEARALKAKEQQNISPVVEEEPE 1006
R+ E + RR Q+L E L + Q+L+ + L+ ++Q + E +
Sbjct: 366 -------REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 1007 FSLPQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANK 1066
Q + +++ E+ + + +E RR +L+ T+ +H K
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRL--KREQEERRDWLKREEETE---RHEQERRK 473
Query: 1067 ECINK 1071
+ + +
Sbjct: 474 QQLKR 478
Score = 32.7 bits (73), Expect = 3.6
Identities = 51/261 (19%), Positives = 108/261 (41%), Gaps = 44/261 (16%)
Query: 739 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQ----RLI 794
KE + E+ K + + +K R E L +E E +LL+EE R +Q +
Sbjct: 969 KEEQLLGEEPEKRRRQEREKK----YREEEELQQE---EEQLLREEREKRRRQEWERQYR 1021
Query: 795 KSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQE 854
K D+L+ + E +++ + E + ++ L ++E +L ++E
Sbjct: 1022 KKDELQQEEEQLLREERE----------KRRLQERERQYREEEELQQEEEQLLGE--ERE 1069
Query: 855 AKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYG 914
++++ + K E+LQ E+ L ++ QE+ + ++ +++
Sbjct: 1070 TRRRQELERQYRK----EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 915 EELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEY 974
EE + + +E+ ++ E++ + L P EKRR Q+LE
Sbjct: 1126 EEREKRRR---QELERQYREEEEVQQEEEQLLREEP--------------EKRRRQELER 1168
Query: 975 EYALKIQKLKEARALKAKEQQ 995
+Y + + +E L +EQ+
Sbjct: 1169 QYREEEELQQEEEQLLREEQE 1189
Score = 32.7 bits (73), Expect = 3.6
Identities = 59/332 (17%), Positives = 135/332 (40%), Gaps = 34/332 (10%)
Query: 739 KEARRTAEQASKPKVPPKSEKENDPLR--TPEALPEEKKIEYRLLKEEIANREKQRLIKS 796
KEA+R ++ + K + E+E R T EE+++ ++ + +E+ R +
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 797 DQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAK 856
++L+ + E + +Q + + ++ ++ + E L+ ++ +
Sbjct: 1365 EELRHQEQGRKFLEEE-------QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 857 KKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEE 916
++E + + + K E+ Q + R FL++ ++Q+ + + R ++ L+ EE
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRR-QERERKFLEE-EQQLRQERHRKFREEEQLLQEREE 1475
Query: 917 LA-----RAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQK 971
R + +E R+ E+DR K + RK E + +++ Q+
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDR----KFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 972 --LEYEYALKIQ------------KLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDL 1017
L+ E L+ Q K +E L+ + ++ E + +F L + +
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 1018 TQDKLTLDTEENDVDDEILSGSSRERRRSFLE 1049
Q++ ++ E+ E +ER R F E
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 64.7 bits (156), Expect = 9e-10
Identities = 60/272 (22%), Positives = 124/272 (45%), Gaps = 42/272 (15%)
Query: 223 ETFEDLLLKYKQIQLELECINKDEKLA----LSSKEENVQEDPKTLNFEDQTSTDNVSIT 278
E E L + K + E + ++EK+ + +E+ + K EDQ +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 279 KDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQ 338
K EE+ + KT Q E K Q+ + ++ ++ K + + + + Q
Sbjct: 555 DQEQKMWDQEERMEKKT-QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 339 GLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKE----QQVM 394
++K Q E+K+ E EE++ E + ++ + K W+Q+E QQ +
Sbjct: 614 EQEEKMQE-----------QEEKMWEQEEKMQEQEEKMW--EQEEKMWEQEEKMWEQQRL 660
Query: 395 KESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAW--KKLQQQKEQERQK 452
E KEKL + + +Q++ K +++Q+ K W +K++++ +++ +K
Sbjct: 661 PEQKEKLWEHEKMQEQEK------------------MQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 453 EEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
DQ K EEE R+RE+++R+ ++ ++E+
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEE 734
Score = 61.2 bits (147), Expect = 1e-08
Identities = 60/323 (18%), Positives = 144/323 (44%), Gaps = 58/323 (17%)
Query: 190 WREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLA 249
WR+ R+ K R+Q + + + E E+ + + ++ E E ++++
Sbjct: 317 WRQEKRLREQEKEL-----REQEKELREQKELREQ-EEQMQEQEEKMWEQEEKMREQEEK 370
Query: 250 LSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLT 309
+ +EE + E K + ++Q D + + + +E+ + + +E
Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE--------- 421
Query: 310 LPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEEL 369
+++K+++ K + T D + +Q++E+ R EKK+ E+EE +
Sbjct: 422 ------QVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER---------EKKMREEEETM 466
Query: 370 SELQLRLLALQSASKKWQQKE----QQVMKESKEKLTKTKTVQQ----------KVKTST 415
E + ++ + W+Q+E QQ + E KEKL + + +Q+ K++
Sbjct: 467 REQEEKMQ--KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 416 KTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQE-----------RQKEEDQRKQAEEEE 464
+ +K ++ +R+Q+ + W++ ++ ++QE ++ +E ++K ++EE
Sbjct: 525 EMWGQEK-KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 465 RRKREEEIRKIRDLSNQEEQYNR 487
+ + EE +R+ +EE+ R
Sbjct: 584 KMREEERMREREKKMREEEEMMR 606
Score = 57.4 bits (137), Expect = 1e-07
Identities = 60/277 (21%), Positives = 130/277 (46%), Gaps = 41/277 (14%)
Query: 224 TFEDLLLKYKQIQLELECINKDE-KLALSSKE-ENVQEDPKTLNFEDQTSTDNVSITKDS 281
T E+L K ++Q +L ++ ++ L+ KE + E K L + QT+T + +
Sbjct: 219 TNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 278
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQ 341
E + Q K + E K RQ+ L + ++++ ++ + L+
Sbjct: 279 E-----ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE---------KMWRQEKRLR 324
Query: 342 DKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKL 401
++E+ L R ++ +K+L E EE++ E + K W+Q+E+ M+E +EK+
Sbjct: 325 EQEKEL--REQEKELREQKELREQEEQMQEQE---------EKMWEQEEK--MREQEEKM 371
Query: 402 -----------TKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQER 450
+ + +QK++ + + K+ ++Q K W+++++ +E E+
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE-EK 430
Query: 451 QKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
+ +E ++K ++EE+ + EE IR+ +EE+ R
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/279 (20%), Positives = 138/279 (49%), Gaps = 30/279 (10%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E++ + ++++ + + I K E+ + +EE ++E + +++ ++ KE+
Sbjct: 272 EEMWRQEEELREQEKKIRKQEE-KMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 286 APEEKT--QVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDK 343
+EK + K + E + Q+ + + ++++ ++ K + + + ++++
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE--KMWRQEERLWEQEKQMREQ 388
Query: 344 EQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQ-QVMKESKEKLT 402
EQ + + E+++ E +E L E + R+ + K W+Q E+ + K+ +E+
Sbjct: 389 EQKMRDQ--------EERMWEQDERLREKEERM---REQEKMWEQVEKMREEKKMQEQEK 437
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQR----- 457
KT+ ++K++ + +K ++ +R+Q+ K K+ + EQE ++ + QR
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 458 -KQAEEEERRKREEEI----RKIRDLSNQEEQYNRFMKL 491
K E+E+ +++EE+I KIRD QEE + + K+
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRD---QEEMWGQEKKM 533
Score = 52.8 bits (125), Expect = 3e-06
Identities = 61/326 (18%), Positives = 145/326 (44%), Gaps = 43/326 (13%)
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEK 247
++W + R+ + R ++ E + E E + + +++Q + E + + E+
Sbjct: 577 KTWDQEEKMREEERMREREKKMREE-----EEMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Query: 248 LALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQK 307
+ +EE + E + + +++ + + + K E+ + + Q E K Q+
Sbjct: 632 -KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 308 LTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEE 367
+ + KK D K + + + + ++++E+ + + E+K+ E EE
Sbjct: 691 KMEKKTQEQEKKTWDQEK-MREEESMREREKKMREEEEMMREQ--------EEKMQEQEE 741
Query: 368 ELSELQLRLLALQSASKKWQQKE----QQVMKESKEKLTKTKTVQQKVKT---------- 413
++ E + + + K W+Q+E QQ + E KEKL + + +Q++ K
Sbjct: 742 KMQEQEEEMW--EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 414 STKTHSAKKVSTTAKQALRKQQTKAW---KKLQQQKEQERQKEE---------DQRKQAE 461
K ++ ++ +R Q+ K W +K+ Q+E+ +EE +++ Q +
Sbjct: 800 EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQ 859
Query: 462 EEERRKREEEIRKIRDLSNQEEQYNR 487
EE+ R++EE++R + ++E+ R
Sbjct: 860 EEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 52.0 bits (123), Expect = 6e-06
Identities = 53/322 (16%), Positives = 143/322 (44%), Gaps = 41/322 (12%)
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEK 247
Q W + R + R + + + E + E + + ++ E E ++E+
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM--REEERMREREKKMREEE 602
Query: 248 LALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQK 307
+ +EE +QE + + +++ + ++ +++ +E+ + + + + ++
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE-----QEEKMWEQ 657
Query: 308 LTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL--TRRISTSDILSEKKLGED 365
LP K +L + + + +Q++E+ + ++ EKK +
Sbjct: 658 QRLPEQKEKL-----------WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 366 EEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVST 425
E+ E +R +K ++E+++M+E +EK+ + + Q+ + K
Sbjct: 707 EKMREEESMR------EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 426 TAK----QALRKQQTKAW--KKLQQQ----KEQERQKEEDQRKQAEEEERRKREEEIRKI 475
K Q L +Q+ K W +K+Q+Q +++E+ ++++++ + +EE+ R +EE++R
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR-- 818
Query: 476 RDLSNQEEQYNRFMKLVGGKRR 497
+E+ + + K+ G + +
Sbjct: 819 ---GQEEKMWGQEEKMWGQEEK 837
Score = 51.6 bits (122), Expect = 8e-06
Identities = 48/273 (17%), Positives = 138/273 (50%), Gaps = 23/273 (8%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E+ L + ++ E E +D++ + ++E ++E + + E + + V ++ K
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR-EQEKMWEQVEKMREEKKMQ 433
Query: 286 APEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQ 345
E+KT+ + + E + +R++ + ++++ ++ + K + + Q++++
Sbjct: 434 EQEKKTRDQEEKMQEEERIRER------EKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 346 NLTRRI--STSDILSEKKLGEDEEELSELQLRLLALQSA----SKKWQQK----EQQVMK 395
+R+ + ++K+ E EE++ E + ++ + K W+Q+ ++ M
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 396 ESKEKLT--KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQT--KAWKKLQQQKEQERQ 451
E +EK+ + K Q+ + KT +K + ++ +R+++ + KK+++++E R+
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 452 KEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
+EE + Q +EE+ +++EE++ + + ++E+
Sbjct: 608 QEE--KMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Score = 50.1 bits (118), Expect = 2e-05
Identities = 53/275 (19%), Positives = 132/275 (48%), Gaps = 25/275 (9%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E+ + + ++ E E ++++ + +E+ ++E K L +++ + + + +
Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQ 351
Query: 286 APEEKT--QVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDK 343
EEK Q + + E K RQ+ L + ++++ + K + + + L++K
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ--KMRDQEERMWEQDERLREK 409
Query: 344 EQNLTRRIS----TSDILSEKKLGEDEEELSELQLRLLALQSASK--KWQQKEQQVMKES 397
E+ + + + EKK+ E E++ + + ++ + + K ++E++ M+E
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 398 KEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAW--KKLQQQKEQERQKEED 455
+EK+ K + + ++ +Q L +Q+ K W +K+Q+Q+E+ ++EE
Sbjct: 470 EEKMQKQEENMWE----------QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 456 QRKQAE---EEERRKREEEIRKIRDLSNQEEQYNR 487
R Q E +E++ R+E++R+ D ++E+ R
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Score = 50.1 bits (118), Expect = 2e-05
Identities = 53/286 (18%), Positives = 130/286 (45%), Gaps = 21/286 (7%)
Query: 222 EETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDS 281
EE D K + +E ++++ +EE ++E+ + E + + + +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQ 341
K EEK Q + + +E + Q+ + +K+ + + + + + Q L
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQE--------QEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 342 DKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKK-WQQ---KEQQVMKES 397
++++ L + ++K+ E EE++ E + Q KK W Q +E++ M+E
Sbjct: 662 EQKEKLWEHEKMQE---QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 398 KEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQR 457
++K+ + + + ++ + + K ++ + +Q+ K W++ ++ EQ+R E+ ++
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQ--EEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 458 KQAEE--EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSK 501
E +E+ K E+ K+RD +E+ + K+ G + + R +
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRD--QEEKMRGQEEKMRGQEEKMRGQ 820
Score = 48.1 bits (113), Expect = 8e-05
Identities = 34/172 (19%), Positives = 83/172 (48%), Gaps = 28/172 (16%)
Query: 359 EKKLGEDEEELSELQLRLLALQSASKK-----------------WQQKEQQVMKESKEKL 401
++KL E E SE+QL + L+ ++ W+Q+E+ ++E ++K+
Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE--LREQEKKI 288
Query: 402 TKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAE 461
K + + + + K +R+Q+ K W++ ++ +EQE++ E +++ E
Sbjct: 289 RKQEEKMWRQEERLREQEGK---------MREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 462 EEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDK 513
++E R++EE++++ + ++E+ R + ++ R + +R K
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/205 (22%), Positives = 104/205 (50%), Gaps = 28/205 (13%)
Query: 288 EEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
EE T+ + + EL + T+ ++ + K + K +S+ ++ +++ ++ L
Sbjct: 200 EELTKERDALSLEL----YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKL 255
Query: 348 TR------RISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKL 401
R ++ T+ + ++++ EEEL E + ++ + K W+Q+E+ +E K +
Sbjct: 256 ERAKFLLPQVQTNTL--QEEMWRQEEELREQEKKIR--KQEEKMWRQEERLREQEGKMRE 311
Query: 402 TKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAE 461
+ K +Q+ K++ K+ ++Q K ++ ++ +EQE Q +E + K E
Sbjct: 312 QEEKMWRQE----------KRLREQEKEL--REQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 462 EEER-RKREEEI-RKIRDLSNQEEQ 484
+EE+ R++EE++ R+ L QE+Q
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQ 384
Score = 36.6 bits (83), Expect = 0.25
Identities = 39/174 (22%), Positives = 88/174 (50%), Gaps = 13/174 (7%)
Query: 345 QNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKT 404
Q +ST +++ + E +E L L L +++ ++K ++ +EKL
Sbjct: 182 QRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL----QEKLPLA 237
Query: 405 KTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKK-LQQQKEQERQKEEDQRKQAEE- 462
++ + +++ + K K+ AK L + QT ++ + +Q+E+ R++E+ RKQ E+
Sbjct: 238 ESEKSEIQLNVK--ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 295
Query: 463 --EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
+E R RE+E K+R+ +E+ + + +L ++ R + + ++ L +Q
Sbjct: 296 WRQEERLREQE-GKMRE--QEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Score = 32.0 bits (71), Expect = 6.2
Identities = 40/185 (21%), Positives = 85/185 (45%), Gaps = 20/185 (10%)
Query: 817 GRIAMVTKQVTDAESKLKKHRILLMKDESVL-----KNLVQQEAKKKESVRNAEAKITKL 871
G + V+ K ++ L K+ L +N + E KK +NAE L
Sbjct: 179 GELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKK---KNAE-----L 230
Query: 872 TEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGK- 930
E+L E + ++ +K+L+ ++ R + + + TL+ EE+ R + ++ K
Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ--EEMWRQEEELREQEKKI 288
Query: 931 RKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALK 990
RK E+ + + +R + + E + +++RL++ E E + ++L+E + L+
Sbjct: 289 RKQEEKMWRQEERLREQEGKM----REQEEKMWRQEKRLREQEKELREQEKELREQKELR 344
Query: 991 AKEQQ 995
+E+Q
Sbjct: 345 EQEEQ 349
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 64.7 bits (156), Expect = 9e-10
Identities = 72/326 (22%), Positives = 142/326 (43%), Gaps = 32/326 (9%)
Query: 191 REPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLAL 250
+E + S+K RS + + +N +ET EDL L + L LE K KL
Sbjct: 650 KEKYKTKDSAKELQRSVEFDREFWKENFFKSDET-EDLFLNMEHESLTLE---KKSKL-- 703
Query: 251 SSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKL-T 309
E+N+++D T +VS ++ +E +K K+F+ ++K L+++
Sbjct: 704 ---EKNIKDDKST-------KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEEREN 753
Query: 310 LPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEEL 369
+P DK+ ++ SL + S GL E+ + I K+ E ++
Sbjct: 754 IPTDKD--------SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQI 805
Query: 370 SELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQ-KVKTSTKTHSAKKVSTTAK 428
E + + ++ K+ + K + K K+KL ++ V + K K +H +K K
Sbjct: 806 KEKDIEKMERKTFEKEKKIKHEH--KSEKDKLDLSECVDKIKEKDKLYSHHTEKCH---K 860
Query: 429 QALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRF 488
+ + + T A KK +++ + + K+ E+ER E + + + + N++ + +
Sbjct: 861 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEY 920
Query: 489 MKLVGGKRRSRSKSSDPDLRRSLDKQ 514
K GK + + + D +S DK+
Sbjct: 921 SKSEKGKNKEKDRELDKK-EKSRDKE 945
Score = 47.0 bits (110), Expect = 2e-04
Identities = 91/459 (19%), Positives = 176/459 (38%), Gaps = 70/459 (15%)
Query: 210 KQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQ 269
K+ SKN +++T + + K + + + E+ SKE+++ E + +
Sbjct: 860 KEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSE 919
Query: 270 TSTDNVSITKDSSKEVAPEEKTQ----VKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAK 325
S K+ +E+ +EK++ + + ++ ++ + G+K + +K
Sbjct: 920 YSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEK------ 973
Query: 326 PLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKK 385
PLSLK T D D ++ ++ D E+ +D+ +++ L L L+S + K
Sbjct: 974 PLSLKEKTKDEPLKTPDGKEK-DKKDKDIDRYKERDKHKDKIQINSL----LKLKSEADK 1028
Query: 386 WQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQ 445
+ K K+++ K + + S +L+ + + W K ++
Sbjct: 1029 PKPKSSPASKDTRPK-----------EKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKE 1077
Query: 446 KEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDP 505
K ++++KE + + E + + +E+ + N+E +RSKSS+
Sbjct: 1078 KIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE--------------LTRSKSSEV 1123
Query: 506 DLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPS 565
+ +KQP D+ Q ++DT + + S F S+ SL
Sbjct: 1124 TDAYTKEKQPKDAVSNRSQ-------SVDTKNVMTLGKSS-----FVSDNSLN------- 1164
Query: 566 LSLPPPPQVSSLPPLSQPYVEGLCV-SLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEE 624
P + P LS V + V S E P PP + + F E E
Sbjct: 1165 ---RSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDS----DFMLESSES 1217
Query: 625 EMLLREELLKSLANKRAFKPEETSSNSDPP---SPPVLN 660
+M + S+A A E S +D P PP N
Sbjct: 1218 QMSFSQSPFLSIAKSPALHERELDSLADLPERIKPPYAN 1256
Score = 43.1 bits (100), Expect = 0.003
Identities = 74/337 (21%), Positives = 140/337 (41%), Gaps = 35/337 (10%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEE----------TFEDLLLKYKQIQLELECINKDE- 246
K K+ S K+ + SK N EE +F + K K ++ E E I D+
Sbjct: 702 KLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE--KIKDLKEERENIPTDKD 759
Query: 247 ----KLALSSKEENVQED--PKTLNFEDQTSTDNVSITKDSSKEVAPE---EKTQVKTFQ 297
L +S+ EE++ K ++ E Q S K + E EK + KTF+
Sbjct: 760 SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE 819
Query: 298 AFELKPLRQKLTLPGDKNRLKKVKDGAKPLS-LKSDTTDSSQGLQDKEQNLTRRISTSDI 356
+ K ++ + DK L + D K L S T+ +K +N T D
Sbjct: 820 --KEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDR 877
Query: 357 -LSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQV--MKESKEKLTKTKTVQQKVKT 413
S +K+ ++ + R LA ++K +Q + SK + K K +++
Sbjct: 878 EKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDK 937
Query: 414 STKTHSAKKVSTTAKQALRKQQTKA---WKKLQQQKE---QERQKEEDQRK-QAEEEERR 466
K+ + ++ T + +++++ + K Q +K +E+ K+E + +E++++
Sbjct: 938 KEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKK 997
Query: 467 KREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSS 503
++ + K RD + Q N +KL + + KSS
Sbjct: 998 DKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSS 1034
Score = 37.0 bits (84), Expect = 0.19
Identities = 52/274 (18%), Positives = 99/274 (36%), Gaps = 60/274 (21%)
Query: 204 GRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKT 263
G +P + + + + E +LLLK E+ + DE S + ++V
Sbjct: 251 GGNPFQANKHGERPVDVAETEELELLLKR-----EVPLSDDDESYTDSEEAQSVNPSSVD 305
Query: 264 LNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDG 323
N + +T D++ SK++ P + +E K
Sbjct: 306 ENIDSETEKDSLIC---ESKQILPSKTPLPSALDEYEFK--------------------- 341
Query: 324 AKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSAS 383
D ++ + + I IL +++ E+E E + L A Q +
Sbjct: 342 -----------------DDDDEEINKMIDDRHILRKEQRKENEPEAEKTHL--FAKQEKA 382
Query: 384 ------KKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKT--HSAKKVSTTAKQAL---- 431
K +QK +V+ S E + +K+ TS ++ T K+ +
Sbjct: 383 FYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGE 442
Query: 432 RKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER 465
KQ+ K +KL+ Q + + +E Q K+ +E R
Sbjct: 443 HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTR 476
Score = 35.0 bits (79), Expect = 0.73
Identities = 62/290 (21%), Positives = 116/290 (40%), Gaps = 23/290 (7%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV 257
KS KS + PSR YSS E+ ++ L+ K+I I + + +K+E V
Sbjct: 386 KSFKSKKQKPSRVL-YSST------ESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYV 438
Query: 258 QEDPKTLNFEDQTSTDNVSITKDSSK---EVAPEEKTQVKTFQAFELKPLRQKLTLPGDK 314
+ + N + K++ + E +E T++ +K G+
Sbjct: 439 VSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNF 498
Query: 315 NRLKKVKDGAKPLSLKSDTTDS---SQGLQDKEQNLTRRISTSDILS----EKKLGEDEE 367
+ KD T S S GL +K+ ++ T LS E L D
Sbjct: 499 RKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLV 558
Query: 368 ELSELQLRLLALQSASKKWQQKEQQVMKESKE-KLTKTKTVQQKVKTSTKTHSAKKVSTT 426
+ L S+ K + KE+ K K+ L + K+K + + + T
Sbjct: 559 RYDNTESEFLPESSSVKSCKHKEKS--KHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCT 616
Query: 427 AKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIR 476
K+ ++ +T KL K +ER+KE+ +++ E+E+ K ++ ++++
Sbjct: 617 LKKMDKEGKTLKKHKL---KHKEREKEKHKKEIEGEKEKYKTKDSAKELQ 663
Score = 33.9 bits (76), Expect = 1.6
Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 39/253 (15%)
Query: 713 DSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPE 772
D + D E+ TNS E Q KP + K + +++PL+TP+ +
Sbjct: 936 DKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKP-LSLKEKTKDEPLKTPDGKEK 994
Query: 773 EKK-IEYRLLKEEIANREKQRLIKSDQLKTSS------SSPANSDVEIDGIGRIAMVTKQ 825
+KK + KE +++K ++ +LK+ + SSPA+ D +
Sbjct: 995 DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTR-------PKEKRL 1047
Query: 826 VTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVN 885
V D + R+L +KD + Q K KE ++ E E++ N N
Sbjct: 1048 VNDDLMQTSFERMLSLKD----LEIEQWHKKHKEKIKQKE------------KERLRNRN 1091
Query: 886 RMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMR 945
+ LK ++ + K T +EL R+K+ + ++ + N+
Sbjct: 1092 CLELK--------IKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQS 1143
Query: 946 LDSSPVSSPRKHS 958
+D+ V + K S
Sbjct: 1144 VDTKNVMTLGKSS 1156
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 64.7 bits (156), Expect = 9e-10
Identities = 72/326 (22%), Positives = 142/326 (43%), Gaps = 32/326 (9%)
Query: 191 REPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLAL 250
+E + S+K RS + + +N +ET EDL L + L LE K KL
Sbjct: 673 KEKYKTKDSAKELQRSVEFDREFWKENFFKSDET-EDLFLNMEHESLTLE---KKSKL-- 726
Query: 251 SSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKL-T 309
E+N+++D T +VS ++ +E +K K+F+ ++K L+++
Sbjct: 727 ---EKNIKDDKST-------KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEEREN 776
Query: 310 LPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEEL 369
+P DK+ ++ SL + S GL E+ + I K+ E ++
Sbjct: 777 IPTDKD--------SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQI 828
Query: 370 SELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQ-KVKTSTKTHSAKKVSTTAK 428
E + + ++ K+ + K + K K+KL ++ V + K K +H +K K
Sbjct: 829 KEKDIEKMERKTFEKEKKIKHEH--KSEKDKLDLSECVDKIKEKDKLYSHHTEKCH---K 883
Query: 429 QALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRF 488
+ + + T A KK +++ + + K+ E+ER E + + + + N++ + +
Sbjct: 884 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEY 943
Query: 489 MKLVGGKRRSRSKSSDPDLRRSLDKQ 514
K GK + + + D +S DK+
Sbjct: 944 SKSEKGKNKEKDRELDKK-EKSRDKE 968
Score = 47.0 bits (110), Expect = 2e-04
Identities = 91/459 (19%), Positives = 176/459 (38%), Gaps = 70/459 (15%)
Query: 210 KQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQ 269
K+ SKN +++T + + K + + + E+ SKE+++ E + +
Sbjct: 883 KEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSE 942
Query: 270 TSTDNVSITKDSSKEVAPEEKTQ----VKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAK 325
S K+ +E+ +EK++ + + ++ ++ + G+K + +K
Sbjct: 943 YSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEK------ 996
Query: 326 PLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKK 385
PLSLK T D D ++ ++ D E+ +D+ +++ L L L+S + K
Sbjct: 997 PLSLKEKTKDEPLKTPDGKEK-DKKDKDIDRYKERDKHKDKIQINSL----LKLKSEADK 1051
Query: 386 WQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQ 445
+ K K+++ K + + S +L+ + + W K ++
Sbjct: 1052 PKPKSSPASKDTRPK-----------EKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKE 1100
Query: 446 KEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDP 505
K ++++KE + + E + + +E+ + N+E +RSKSS+
Sbjct: 1101 KIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE--------------LTRSKSSEV 1146
Query: 506 DLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPS 565
+ +KQP D+ Q ++DT + + S F S+ SL
Sbjct: 1147 TDAYTKEKQPKDAVSNRSQ-------SVDTKNVMTLGKSS-----FVSDNSLN------- 1187
Query: 566 LSLPPPPQVSSLPPLSQPYVEGLCV-SLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEE 624
P + P LS V + V S E P PP + + F E E
Sbjct: 1188 ---RSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDS----DFMLESSES 1240
Query: 625 EMLLREELLKSLANKRAFKPEETSSNSDPP---SPPVLN 660
+M + S+A A E S +D P PP N
Sbjct: 1241 QMSFSQSPFLSIAKSPALHERELDSLADLPERIKPPYAN 1279
Score = 43.1 bits (100), Expect = 0.003
Identities = 74/337 (21%), Positives = 140/337 (41%), Gaps = 35/337 (10%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEE----------TFEDLLLKYKQIQLELECINKDE- 246
K K+ S K+ + SK N EE +F + K K ++ E E I D+
Sbjct: 725 KLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE--KIKDLKEERENIPTDKD 782
Query: 247 ----KLALSSKEENVQED--PKTLNFEDQTSTDNVSITKDSSKEVAPE---EKTQVKTFQ 297
L +S+ EE++ K ++ E Q S K + E EK + KTF+
Sbjct: 783 SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE 842
Query: 298 AFELKPLRQKLTLPGDKNRLKKVKDGAKPLS-LKSDTTDSSQGLQDKEQNLTRRISTSDI 356
+ K ++ + DK L + D K L S T+ +K +N T D
Sbjct: 843 --KEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDR 900
Query: 357 -LSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQV--MKESKEKLTKTKTVQQKVKT 413
S +K+ ++ + R LA ++K +Q + SK + K K +++
Sbjct: 901 EKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDK 960
Query: 414 STKTHSAKKVSTTAKQALRKQQTKA---WKKLQQQKE---QERQKEEDQRK-QAEEEERR 466
K+ + ++ T + +++++ + K Q +K +E+ K+E + +E++++
Sbjct: 961 KEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKK 1020
Query: 467 KREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSS 503
++ + K RD + Q N +KL + + KSS
Sbjct: 1021 DKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSS 1057
Score = 37.0 bits (84), Expect = 0.19
Identities = 52/274 (18%), Positives = 99/274 (36%), Gaps = 60/274 (21%)
Query: 204 GRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKT 263
G +P + + + + E +LLLK E+ + DE S + ++V
Sbjct: 274 GGNPFQANKHGERPVDVAETEELELLLKR-----EVPLSDDDESYTDSEEAQSVNPSSVD 328
Query: 264 LNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDG 323
N + +T D++ SK++ P + +E K
Sbjct: 329 ENIDSETEKDSLIC---ESKQILPSKTPLPSALDEYEFK--------------------- 364
Query: 324 AKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSAS 383
D ++ + + I IL +++ E+E E + L A Q +
Sbjct: 365 -----------------DDDDEEINKMIDDRHILRKEQRKENEPEAEKTHL--FAKQEKA 405
Query: 384 ------KKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKT--HSAKKVSTTAKQAL---- 431
K +QK +V+ S E + +K+ TS ++ T K+ +
Sbjct: 406 FYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGE 465
Query: 432 RKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER 465
KQ+ K +KL+ Q + + +E Q K+ +E R
Sbjct: 466 HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTR 499
Score = 35.0 bits (79), Expect = 0.73
Identities = 62/290 (21%), Positives = 116/290 (40%), Gaps = 23/290 (7%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV 257
KS KS + PSR YSS E+ ++ L+ K+I I + + +K+E V
Sbjct: 409 KSFKSKKQKPSRVL-YSST------ESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYV 461
Query: 258 QEDPKTLNFEDQTSTDNVSITKDSSK---EVAPEEKTQVKTFQAFELKPLRQKLTLPGDK 314
+ + N + K++ + E +E T++ +K G+
Sbjct: 462 VSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNF 521
Query: 315 NRLKKVKDGAKPLSLKSDTTDS---SQGLQDKEQNLTRRISTSDILS----EKKLGEDEE 367
+ KD T S S GL +K+ ++ T LS E L D
Sbjct: 522 RKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLV 581
Query: 368 ELSELQLRLLALQSASKKWQQKEQQVMKESKE-KLTKTKTVQQKVKTSTKTHSAKKVSTT 426
+ L S+ K + KE+ K K+ L + K+K + + + T
Sbjct: 582 RYDNTESEFLPESSSVKSCKHKEKS--KHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCT 639
Query: 427 AKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIR 476
K+ ++ +T KL K +ER+KE+ +++ E+E+ K ++ ++++
Sbjct: 640 LKKMDKEGKTLKKHKL---KHKEREKEKHKKEIEGEKEKYKTKDSAKELQ 686
Score = 33.9 bits (76), Expect = 1.6
Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 39/253 (15%)
Query: 713 DSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPE 772
D + D E+ TNS E Q KP + K + +++PL+TP+ +
Sbjct: 959 DKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKP-LSLKEKTKDEPLKTPDGKEK 1017
Query: 773 EKK-IEYRLLKEEIANREKQRLIKSDQLKTSS------SSPANSDVEIDGIGRIAMVTKQ 825
+KK + KE +++K ++ +LK+ + SSPA+ D +
Sbjct: 1018 DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTR-------PKEKRL 1070
Query: 826 VTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVN 885
V D + R+L +KD + Q K KE ++ E E++ N N
Sbjct: 1071 VNDDLMQTSFERMLSLKD----LEIEQWHKKHKEKIKQKE------------KERLRNRN 1114
Query: 886 RMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMR 945
+ LK ++ + K T +EL R+K+ + ++ + N+
Sbjct: 1115 CLELK--------IKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQS 1166
Query: 946 LDSSPVSSPRKHS 958
+D+ V + K S
Sbjct: 1167 VDTKNVMTLGKSS 1179
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 63.9 bits (154), Expect = 1e-09
Identities = 35/171 (20%), Positives = 96/171 (56%), Gaps = 7/171 (4%)
Query: 318 KKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLL 377
+K+++ K + T D + ++++E+ R + E+ + E EE++ E + ++
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQEQEEKMR 591
Query: 378 ALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTK 437
+ K W+Q+E+ M+E +EK+ + + + + K +++ ++ +++Q+ K
Sbjct: 592 --EQEEKMWEQEEK--MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 438 AWKKLQQQKEQ-ERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
W++ ++ +EQ E+ +E++++ Q +EE+ R++EE+++ + ++E+ R
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 63.5 bits (153), Expect = 2e-09
Identities = 53/309 (17%), Positives = 150/309 (48%), Gaps = 33/309 (10%)
Query: 190 WREPSPPRKSSKSFGRSPSR---KQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDE 246
W + R+ + R R ++ + E + + E + + ++++ + E + + E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 247 KL----ALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELK 302
K+ +EE ++E K + E++T + EEK Q + +E +
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQ-------------EEKMQKQEENMWEQE 426
Query: 303 PLR-QKLTLPGDKNRL---KKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILS 358
Q+ LP K +L +K+++ + + + + + + +E+ + R+ +
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE--Q 484
Query: 359 EKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTV---QQKVKTST 415
E ++ E EE++ + + ++ + W+Q E+ ++E +E++ + K + ++K++
Sbjct: 485 EDQMWEQEEKMRDQEQKMW--DQEERMWEQDER--LREKEERMREQKKMWQQEEKMREEK 540
Query: 416 KTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKI 475
KT +K + ++ +R+++ ++ + ++E+E +E++++ Q +EE+ R++EE++ +
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 476 RDLSNQEEQ 484
+ ++E+
Sbjct: 601 EEKMQEQEE 609
Score = 62.8 bits (151), Expect = 3e-09
Identities = 61/316 (19%), Positives = 146/316 (46%), Gaps = 34/316 (10%)
Query: 188 QSWREPSPPRKSSKSFGRSPS---RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINK 244
+ WR+ R+ K + R++ + E + E E + + K++ +
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL--------R 286
Query: 245 DEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFEL-KP 303
+++ L +E+ ++E K E+Q + + K EEK + + +E K
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 304 LRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLG 363
+R++ D+ +D + L K + + + ++E+ + + EKK+
Sbjct: 347 MREQEQKMRDQEERMWEQD--ERLREKEERMREQEKMWEQEEKMQEEERIRE--REKKMR 402
Query: 364 EDEEELSELQLRLLALQSASKKWQQKEQ----QVMKESKEKLTKTKTVQ----------Q 409
E+EE + E + ++ + W+Q+E+ Q + E KEKL + + +Q +
Sbjct: 403 EEEETMREQEEKMQ--KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 410 KVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER-RKR 468
K++ + +K ++ +R+Q+ + W++ ++ ++QE++ + + + E++ER R++
Sbjct: 461 KIRDQEEMWGQEK-KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 469 EEEIRKIRDLSNQEEQ 484
EE +R+ + + QEE+
Sbjct: 520 EERMREQKKMWQQEEK 535
Score = 61.2 bits (147), Expect = 1e-08
Identities = 60/274 (21%), Positives = 132/274 (48%), Gaps = 40/274 (14%)
Query: 224 TFEDLLLKYKQIQLELECINKDE-KLALSSKE-ENVQEDPKTLNFEDQTSTDNVSITKDS 281
T E+L K ++Q +L ++ ++ L+ KE + E K L + QT+T + +
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQ 341
E + Q K + E K RQ+ L + ++++ ++ + + L+
Sbjct: 241 E-----ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR---------QEKRLR 286
Query: 342 DKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKL 401
++E+ L R ++ +KKL E EE++ E + K W+Q+E+ M+E +EK+
Sbjct: 287 EQEKEL--REQEKELREQKKLREQEEQMQEQE---------EKMWEQEEK--MREQEEKM 333
Query: 402 -----------TKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQER 450
+ + +QK++ + + K+ ++Q K W++ ++ +E+ER
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 451 QKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
+E +++ + EEE R++EE+++K + ++E+
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Score = 60.5 bits (145), Expect = 2e-08
Identities = 59/296 (19%), Positives = 141/296 (47%), Gaps = 39/296 (13%)
Query: 234 QIQLELECINKDEKLALSSKEENVQE-DPKTLNFEDQTSTDNVSITKDSSKE----VAPE 288
++Q L ++ K A EE +E D +L T T+ K++ + +A
Sbjct: 142 ELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAES 201
Query: 289 EKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLT 348
EK++++ +K L++KL R K + + +L+ + + L+++E+ +
Sbjct: 202 EKSEIQ----LNVKELKRKL------ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 349 RRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQ 408
++ E+K+ EE L E + ++ + +K +++E+++ ++ KE + K ++
Sbjct: 252 KQ--------EEKMWRQEERLREQEGKM---REQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 409 QKVKTSTKTHSAKKVSTTA---KQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER 465
++ K + ++ ++ +R+Q+ K W++ ++ EQE+Q E ++K ++EER
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 466 --------RKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDK 513
R++EE +R+ + QEE+ ++ +R + + + +R +K
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERI--REREKKMREEEETMREQEEK 414
Score = 60.1 bits (144), Expect = 2e-08
Identities = 47/230 (20%), Positives = 115/230 (50%), Gaps = 17/230 (7%)
Query: 244 KDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKP 303
++E+ + +EE +Q+ + + +++ + + K + +EK Q + + +E +
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-LWEQEKMQEQEEKIWEQEE 460
Query: 304 -LRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKL 362
+R + + G + KK+ K + + + ++D+EQ + + E+++
Sbjct: 461 KIRDQEEMWGQE---KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--------EERM 509
Query: 363 GEDEEELSELQLRLLALQSASKKWQQKEQ-QVMKESKEKLTKTKTVQQKVKTSTKTHSAK 421
E +E L E + R+ + K WQQ+E+ + K+++E+ KT ++K++ + +
Sbjct: 510 WEQDERLREKEERM---REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 422 KVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEE 471
K ++ +R+Q+ K ++ ++ +EQE + E + K E+EE+ +EE
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
Score = 59.7 bits (143), Expect = 3e-08
Identities = 50/260 (19%), Positives = 132/260 (50%), Gaps = 30/260 (11%)
Query: 244 KDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKP 303
+D++ + +EE + E + L +++ + + + K + E+KTQ + + ++ +
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK-MREEKKTQEQEKKTWDQEE 554
Query: 304 -LRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKL 362
+R++ + + R KK+++ + + + + +Q++E+ + + E+K+
Sbjct: 555 KMREEERM---REREKKMREEEEMMR------EQEEKMQEQEEKMREQ--------EEKM 597
Query: 363 GEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKK 422
E EE++ E + ++ + K W+Q+E+ M+E +E + + + Q + K ++
Sbjct: 598 WEQEEKMQEQEEKMW--EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ--EQEEKMWEQEE 653
Query: 423 VSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIR-KIRDLSNQ 481
++ +R+Q+ K Q ++E+ +E++++ Q +EE+ R++EE++R + + Q
Sbjct: 654 KMREQEEKMREQEEK------MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 482 EEQYNRFMKLVGGKRRSRSK 501
EE+ + + G+ R K
Sbjct: 708 EEKMWGQEEKMWGQEEMREK 727
Score = 57.0 bits (136), Expect = 2e-07
Identities = 64/294 (21%), Positives = 135/294 (45%), Gaps = 42/294 (14%)
Query: 222 EETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDS 281
E ++ L K+++ +LE K L + N ++ + E++ I K
Sbjct: 200 ESEKSEIQLNVKELKRKLE----RAKFLLPQVQTNTLQE-EMWRQEEELREQEKKIRKQE 254
Query: 282 SKEVAPEEKT--QVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQG 339
K EE+ Q + E K RQ+ L + + K++++ K L + + +
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRL---REQEKELREQEKELREQKKLREQEEQ 311
Query: 340 LQDKEQNL------TRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQ----- 388
+Q++E+ + R E++L E E+++ E + ++ + W+Q
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR--DQEERMWEQDERLR 369
Query: 389 ------KEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKL 442
+EQ+ M E +EK+ + + ++++ K K ++ ++ ++KQ+ W++
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREK---KMREEEETMREQEEKMQKQEENMWEQE 426
Query: 443 QQQKEQER---QKEE--DQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKL 491
+++ +Q+R QKE+ +Q K E+EE+ +EE KIRD QEE + + K+
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE--KIRD---QEEMWGQEKKM 475
Score = 53.1 bits (126), Expect = 3e-06
Identities = 61/304 (20%), Positives = 144/304 (47%), Gaps = 38/304 (12%)
Query: 226 EDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEV 285
E+L + K+I+ + E + + E+ L +E ++E + + +++ + ++ KE+
Sbjct: 241 EELREQEKKIRKQEEKMWRQEE-RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 286 APEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQ 345
++K + Q +++ +K+ +K R ++ K + L + + ++++EQ
Sbjct: 300 REQKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL----WEQEKQMREQEQ 352
Query: 346 NLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKE-----------QQVM 394
+ + E+++ E +E L E + R+ + K W+Q+E ++ M
Sbjct: 353 KMRDQ--------EERMWEQDERLREKEERM---REQEKMWEQEEKMQEEERIREREKKM 401
Query: 395 KESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAW--KKLQQQKEQERQK 452
+E +E + + + QK + + K+ +Q L +Q+ K W +K+Q+Q+E+ ++
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQ---QQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Query: 453 EEDQRKQAE---EEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRR 509
EE R Q E +E++ R+E++R+ D ++E+ R + + R D LR
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 510 SLDK 513
++
Sbjct: 519 KEER 522
Score = 47.4 bits (111), Expect = 1e-04
Identities = 56/287 (19%), Positives = 122/287 (42%), Gaps = 13/287 (4%)
Query: 190 WREPSPPRKSSKSFGRSPS--RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEK 247
W + R + +G+ R++ + + E+ + + K E +DE+
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 248 LALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQK 307
L KEE ++E K E++ + + + K EEK + + K +R++
Sbjct: 516 LR--EKEERMREQKKMWQQEEKMREEKKT-QEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 308 LTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTS-DILSEKKLGEDE 366
+ ++ K + K + + + +Q++E+ + + + E K+ E E
Sbjct: 573 EEMMREQEE-KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 367 EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTT 426
E + E + ++ + K W+Q+E+ M+E +EK+ + + Q + + K
Sbjct: 632 EMMWEQEEKMQ--EQEEKMWEQEEK--MREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 427 AKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIR 473
K +R+Q+ K + ++ QE + + K +EE R++EE IR
Sbjct: 688 EK--MREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Score = 44.3 bits (103), Expect = 0.001
Identities = 45/234 (19%), Positives = 108/234 (46%), Gaps = 24/234 (10%)
Query: 246 EKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDS-----SKEVAPEE---KTQVKTFQ 297
E+ + +EE ++E+ KT E +T + ++ K++ EE + Q + Q
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 298 AFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDIL 357
E K Q+ + + ++++ ++ K + +Q++E+ + +
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ------- 637
Query: 358 SEKKLGEDEEELSELQLRLLALQSASKKWQQK---EQQVMKESKEKLTKTKTVQQKVKTS 414
E+K+ E EE++ E + ++ + ++ ++K +++ M+E +EK+ + ++ +
Sbjct: 638 -EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696
Query: 415 TKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQER---QKEEDQRKQAEEEER 465
+ K K + Q+ K W + + ++++ER QKE+ Q + E EER
Sbjct: 697 MRGQEEKMWGQEEK--MWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 32.7 bits (73), Expect = 3.6
Identities = 40/185 (21%), Positives = 86/185 (46%), Gaps = 20/185 (10%)
Query: 817 GRIAMVTKQVTDAESKLKKHRILLMKDESVL-----KNLVQQEAKKKESVRNAEAKITKL 871
G + V+ K ++ L K+ L +N + E KK +NAE L
Sbjct: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK---KNAE-----L 192
Query: 872 TEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGK- 930
E+L+ E + ++ +K+L+ ++ R + + + TL+ EE+ R + ++ K
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ--EEMWRQEEELREQEKKI 250
Query: 931 RKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALK 990
RK E+ + + +R + + E + +++RL++ E E + ++L+E + L+
Sbjct: 251 RKQEEKMWRQEERLREQEGKM----REQEEKMRRQEKRLREQEKELREQEKELREQKKLR 306
Query: 991 AKEQQ 995
+E+Q
Sbjct: 307 EQEEQ 311
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 63.5 bits (153), Expect = 2e-09
Identities = 95/457 (20%), Positives = 184/457 (40%), Gaps = 52/457 (11%)
Query: 679 SQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMI 738
+Q + + GP + LP+ + ++ ESDGE + LE++
Sbjct: 226 TQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQ 285
Query: 739 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQ 798
+ +R + K +S KE L T E +++++ RL +E+ + + + +
Sbjct: 286 QRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERL--QELEKIKDLHMAEKTK 343
Query: 799 LKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESV--LKNLVQQEAK 856
L T N +++ K + AE+K + H L MK+E + L++ ++Q
Sbjct: 344 LITQLRDAKNLIEQLE-------QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 396
Query: 857 KKESVRNAEAK-----ITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTL 911
+ E +R + K +L + L +K R ++ EQI + ++ + ++ ++L
Sbjct: 397 QGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTI-EKTSEEERISL 455
Query: 912 KYGEELARAKAVASKEIGKRKLEQ----DRFGPNKMMRLDSSPVSSPRKHSAELIAMEKR 967
+ +EL+R K + K EQ + ++ R + + E K
Sbjct: 456 Q--QELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKV 513
Query: 968 RLQKLEYEYALKIQKLKEAR---ALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTL 1024
L+K + EY LKI + KE + AL+ E Q + + E E + L DL Q+ T
Sbjct: 514 ALEKSQSEY-LKISQEKEQQESLALEELELQKKAILTESENK-------LRDLQQEAETY 565
Query: 1025 DTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNT-------- 1076
T +++ + + +S + + KH NKE + K+
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKH----NKEITVMVEKHKTELESLKH 621
Query: 1077 ------VEKPELFLGLKIGELQKLYSKADSLKQLILK 1107
EK ++ E++KL K + K+ +LK
Sbjct: 622 QQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLK 658
Score = 61.6 bits (148), Expect = 7e-09
Identities = 64/311 (20%), Positives = 132/311 (42%), Gaps = 18/311 (5%)
Query: 210 KQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQ 269
K+ S E C T E L+ +Q+ L+ + K + L ++ K + + + N +Q
Sbjct: 299 KETIQSHKEQCTLLTSEKEALQ-EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ 357
Query: 270 TSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSL 329
D + ++ +++ E ++K + +L+ +++T G++ R +K K
Sbjct: 358 LEQDKGMVIAETKRQM--HETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEE 415
Query: 330 KSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQK 389
++Q ++ + L + EK EEE LQ Q S+ Q+
Sbjct: 416 LEKALSTAQKTEEARRKLKAEMDEQIKTIEKT---SEEERISLQ------QELSRVKQEV 466
Query: 390 EQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQE 449
+ K S+E++ K + + +K + KK+ T ++ + + K + +
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIS 526
Query: 450 RQKEEDQRKQAEEEERRKR---EEEIRKIRDLSNQEEQY-NRFMKLVGGKRRS--RSKSS 503
++KE+ + EE E +K+ E K+RDL + E Y R ++L +S +K+
Sbjct: 527 QEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 586
Query: 504 DPDLRRSLDKQ 514
DL L+ +
Sbjct: 587 SKDLAVHLEAE 597
Score = 49.7 bits (117), Expect = 3e-05
Identities = 61/283 (21%), Positives = 128/283 (45%), Gaps = 27/283 (9%)
Query: 208 SRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFE 267
SR + +++ E E+ + +++++ L K E+ K E + E KT+ E
Sbjct: 389 SRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE-MDEQIKTI--E 445
Query: 268 DQTSTDNVSITKDSS--KEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAK 325
+ + +S+ ++ S K+ + + Q +L+ L +K ++ KK++ +
Sbjct: 446 KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRER 505
Query: 326 P------LSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQ------ 373
++L+ ++ + Q+KEQ + + ++ + L E E +L +LQ
Sbjct: 506 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 374 -LRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQK-VKTSTKTHSAKKVSTTAKQAL 431
R+L L+S+ +K Q+ + K+ L K K + + H T ++L
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHK------TELESL 619
Query: 432 RKQQTKAW-KKLQQQKEQERQKEEDQRKQAEEE-ERRKREEEI 472
+ QQ W +KLQ K+Q + + E R++ E+E E +++EI
Sbjct: 620 KHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEI 662
Score = 47.4 bits (111), Expect = 1e-04
Identities = 65/297 (21%), Positives = 138/297 (46%), Gaps = 46/297 (15%)
Query: 217 NENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVS 276
++ CV++T+E+ + ++ N EK L + +E+ + +FE +
Sbjct: 1726 SQGCVQKTYEEKISVLQR--------NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERL 1777
Query: 277 ITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTL--------PGDKNRLKKVKDGAKPLS 328
I + ++ E+++ + Q EL+ +K +L G KN ++ ++
Sbjct: 1778 IKLEHAEAKQHEDQSMIGHLQE-ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQN------ 1830
Query: 329 LKSDTTDSSQGLQDKE---QNLTRRISTSD--ILSEKKLGEDE-EELSELQLRLLALQSA 382
L++ D + LQ+KE Q L ++I D ++ +K++ E EEL+ +L ALQ
Sbjct: 1831 LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890
Query: 383 SKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH----------SAKKVSTTAKQALR 432
+ K ++++E+ E+ +K+ VQ K+ ++ + + ++ K+ +R
Sbjct: 1891 DGR--NKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVR 1948
Query: 433 KQQTKAWKKLQQQKEQE-RQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRF 488
Q+ + + Q+E E +KE DQ E EE+ K+E+E +++ S ++ F
Sbjct: 1949 LQKDLRMLRKEHQQELEILKKEYDQ----EREEKIKQEQEDLELKHNSTLKQLMREF 2001
Score = 43.1 bits (100), Expect = 0.003
Identities = 61/289 (21%), Positives = 128/289 (44%), Gaps = 45/289 (15%)
Query: 226 EDLLLKYKQIQL--ELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSK 283
E+L KY+++Q +++ NK +L EEN +E K+ + + ++ + D
Sbjct: 1875 EELTSKYEKLQALQQMDGRNKPTELL----EENTEEKSKSHLVQPKLLSNMEAQHNDLEF 1930
Query: 284 EVAPEEKTQVKTFQAF-----ELKPLRQK-------LTLPGDKNRLKKVKDGAKPLSLKS 331
++A E+ + K + +L+ LR++ L D+ R +K+K + L LK
Sbjct: 1931 KLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKH 1990
Query: 332 DTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQ 391
++T L+ + +++ + E + E + E++ LL + Q++
Sbjct: 1991 NST-----LKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELL------ESHQEETN 2039
Query: 392 QVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAK-QALRKQQTKAWKKLQQQKEQER 450
Q++K+ EK +++ K + A++ TAK + L+ Q + KK QQ+ EQE
Sbjct: 2040 QLLKKIAEK---DDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEE 2096
Query: 451 QKEED------------QRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
D Q+ + + K +E +I +L ++ ++Y +
Sbjct: 2097 NPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2145
Score = 42.4 bits (98), Expect = 0.005
Identities = 146/772 (18%), Positives = 297/772 (38%), Gaps = 123/772 (15%)
Query: 280 DSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQG 339
+S E E+ T VKT + + + RQ+ L K ++ K+ L T +
Sbjct: 265 ESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLL------TSEKEA 318
Query: 340 LQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKE 399
LQ++ L R+ + + + + E + +++L+ ++ ++ +Q + V+ E+K
Sbjct: 319 LQEQ---LDERLQELEKIKDLHMAEKTKLITQLR----DAKNLIEQLEQDKGMVIAETKR 371
Query: 400 KLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQ 459
++ +T ++ K + + S K TT + LR+Q+ K+ ER E+ K
Sbjct: 372 QMHET--LEMKEEEIAQLRSRIKQMTTQGEELREQKEKS----------ERAAFEELEKA 419
Query: 460 AEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSG 519
+ K EE RK++ + +EQ ++ K+S+ + R SL ++
Sbjct: 420 LSTAQ--KTEEARRKLK--AEMDEQI-----------KTIEKTSEEE-RISLQQE----- 458
Query: 520 GGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPP 579
++ +D ++S + +Q E L+ L
Sbjct: 459 -----LSRVKQEVVDVMKKSSEEQIAKLQKLHEKE-----------LARKEQELTKKLQT 502
Query: 580 LSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREEL---LKSL 636
+ + E + V+LE Q + E+E++E L EEL K++
Sbjct: 503 REREFQEQMKVALEK---------------SQSEYLKISQEKEQQESLALEELELQKKAI 547
Query: 637 ANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRLPR 696
+ K + ++ +L + +S + S+ + + +
Sbjct: 548 LTESENKLRDLQQEAETYRTRILELESSLEKS---LQENKNQSKDLAVHLEAEKNKHNKE 604
Query: 697 TVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPK-VPP 755
+ + KHK+ + +L D+ + +E + ++ + E K K +
Sbjct: 605 ITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIF 664
Query: 756 KSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDG 815
++ E +T E L + K+ E L E++ K R ++L E++
Sbjct: 665 QAHIEEMNEKTLEKL-DVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELE- 722
Query: 816 IGRIAMVTKQVT----DAESKLKKHRILLMKDESVLKNLVQQ-EAKKKES---------- 860
A + +Q +S +K+H + + + E LK+ + Q E KE
Sbjct: 723 ----AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAH 778
Query: 861 VRNAEAKITKLTEQLQATEKILNVNRMF-------LKKLQEQIHRVQQRV----TIKKAL 909
V N EA I + +LQ L+V + + K +EQ+ ++QQ++ T + L
Sbjct: 779 VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL 838
Query: 910 TLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRK-HSAELIAMEKRR 968
T + E A+ K V + E+ K++ + M +L+ +K S + K
Sbjct: 839 TKQVAEVEAQKKDVCT-ELDAHKIQVQ----DLMQQLEKQNSEMEQKVKSLTQVYESKLE 893
Query: 969 LQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQD 1020
E E +I KE L+ +E Q + + + S + S+H L ++
Sbjct: 894 DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQ-KLSAKEDSIHILNEE 944
Score = 40.0 bits (92), Expect = 0.023
Identities = 63/295 (21%), Positives = 135/295 (45%), Gaps = 40/295 (13%)
Query: 200 SKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLEL---ECINKDEKLALSSKEEN 256
S F + Q+ ++++N V+E QIQLEL E KDE++ L KEE
Sbjct: 1439 SNKFSEWKKKAQSRFTQHQNTVKEL---------QIQLELKSKEAYEKDEQINLL-KEEL 1488
Query: 257 VQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNR 316
Q++ + + + D + K KE E + + +T + EL+ + T+
Sbjct: 1489 DQQNKRFDCLKGEMEDDKSKMEK---KESNLETELKSQTARIMELEDHITQKTI-----E 1540
Query: 317 LKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKK---LGEDEEELSELQ 373
++ + + K + + D ++ KE L +++ L E+K + E EE++ L+
Sbjct: 1541 IESLNEVLKNYNQQKD-------IEHKE--LVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591
Query: 374 LRLLALQSA--SKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQAL 431
++ ++++ +KK + + + +SKE+ K + + +++ K K+ + A+
Sbjct: 1592 NQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAI 1651
Query: 432 RKQQTKAWKKLQQQKE---QERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEE 483
+KQ ++ ++Q + + E + + Q E E EE+++ + S+Q E
Sbjct: 1652 KKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE--SSQSE 1704
Score = 39.7 bits (91), Expect = 0.030
Identities = 73/337 (21%), Positives = 138/337 (40%), Gaps = 60/337 (17%)
Query: 211 QNYSSKNENCVEETFEDLLLKYKQIQLELE-----CINKDEKLALSSKEENVQEDPKTLN 265
Q+ S +E ++ ED L++K++ EL C K E L + E + N
Sbjct: 1186 QSLKSSHEKS-NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTN 1244
Query: 266 FEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLT---------------- 309
+S + + +V +E +KT EL+ ++LT
Sbjct: 1245 ----AILSRISHCQHRTTKV--KEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQ 1298
Query: 310 LPGDKNRLKKVKDGAKPL-----SLKSDTTDSSQGLQDKE-------QNLTRRISTSDIL 357
L +N++K +K + L +L+ + + Q +KE + L+ I+ ++
Sbjct: 1299 LEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLM 1358
Query: 358 SEKKLGEDEEELSELQLRLLALQ---SASKKWQQKE-------QQVMKESKEKLTKTKTV 407
E+ L E + E+S L +L L S +KE +Q +E E L + + +
Sbjct: 1359 KEE-LKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDL 1417
Query: 408 QQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQ---KEEDQRKQAEEEE 464
KV T +K +K+S + + WKK Q + + Q KE + + + +E
Sbjct: 1418 SFKVDTLSK----EKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1473
Query: 465 RRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSK 501
+++E+I +++ ++Q RF L G +SK
Sbjct: 1474 AYEKDEQINLLKE--ELDQQNKRFDCLKGEMEDDKSK 1508
Score = 38.5 bits (88), Expect = 0.066
Identities = 65/309 (21%), Positives = 132/309 (42%), Gaps = 20/309 (6%)
Query: 221 VEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKD 280
+EE E L K Q ELE ++ + L ++ + ++E+ L + + D
Sbjct: 668 IEEMNEKTLEKLDVKQTELESLSSELSEVLKARHK-LEEELSVLKDQTDKMKQELEAKMD 726
Query: 281 SSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKV-KDGAKPL--------SLKS 331
K ++ + + E+ R + L N+L+ + K+ K L +L++
Sbjct: 727 EQKNHHQQQVDSI--IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEA 784
Query: 332 DTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQ 391
D S LQ L S E+ EE+L++LQ +LL L+ +++ +Q
Sbjct: 785 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAY-EEQLAQLQQKLLDLE--TERILLTKQ 841
Query: 392 QVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQ-QKEQER 450
E+++K T+ K++ +K ++ +Q ++ KL+ KEQE+
Sbjct: 842 VAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQ 901
Query: 451 QKE---EDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDL 507
K+ E + + E +K+E EI + LS +E+ + + K +++ K +
Sbjct: 902 TKQILVEKENMILQMREGQKKEIEI-LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 960
Query: 508 RRSLDKQPT 516
+++ + Q T
Sbjct: 961 QKAKEMQET 969
Score = 37.7 bits (86), Expect = 0.11
Identities = 43/180 (23%), Positives = 86/180 (47%), Gaps = 13/180 (7%)
Query: 734 LESMIKEARRTAEQASKPKVPPKSEKENDPLR------TPEALPEEKKIEYRLLKEEI-- 785
LE + KE + E+ K + K N L+ + +E+++E + KE I
Sbjct: 1964 LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTI-KETINK 2022
Query: 786 ANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDA--ESKLKKHRILLMKD 843
A + L++S Q +T+ ++ + D + R A +++ DA E K R L +
Sbjct: 2023 AQEVEAELLESHQEETNQLLKKIAEKD-DDLKRTAKRYEEILDAREEEMTAKVRDLQTQL 2081
Query: 844 ESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRV 903
E + K QQ+ +++E+ N I +L QL +++ +++ ++ +EQIH ++ R+
Sbjct: 2082 EELQKKY-QQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRL 2140
Score = 37.4 bits (85), Expect = 0.15
Identities = 57/312 (18%), Positives = 135/312 (43%), Gaps = 39/312 (12%)
Query: 703 KHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKS----- 757
K+ +V + + +++ +A ++ +VF ++ ++E T Q + K+
Sbjct: 1807 KYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTC-QILEQKIKELDSCLVR 1865
Query: 758 EKENDPLRTPEALPEEKKIEY-----------RLLKEEIANREKQRLIKSDQLKTSSSSP 806
+KE + E + +K++ LL+E + K L++ L +
Sbjct: 1866 QKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQH 1925
Query: 807 ANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAK--KKESVRNA 864
+ + ++ G R + KL K + L KD +L+ QQE + KKE +
Sbjct: 1926 NDLEFKLAGAER----------EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER 1975
Query: 865 EAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVA 924
E KI + E L+ K + + +++ Q+ + +Q + +T+K E + +A+ V
Sbjct: 1976 EEKIKQEQEDLEL--KHNSTLKQLMREFNTQLAQKEQEL----EMTIK--ETINKAQEVE 2027
Query: 925 SKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLK 984
++ + + E ++ K+ D + +++ L A E+ K+ + ++++L+
Sbjct: 2028 AELLESHQEETNQL-LKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVR-DLQTQLEELQ 2085
Query: 985 EARALKAKEQQN 996
+ K ++++N
Sbjct: 2086 KKYQQKLEQEEN 2097
Score = 35.8 bits (81), Expect = 0.43
Identities = 62/332 (18%), Positives = 129/332 (38%), Gaps = 23/332 (6%)
Query: 197 RKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEEN 256
R S+S + K+ K ++ + K +Q + E + L +E
Sbjct: 1628 RLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERERE 1687
Query: 257 VQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNR 316
V + L + + ++ + + + S+K VA + + Q K +K+++ +N
Sbjct: 1688 VHILEEKLKSVESSQSETLIVPR-SAKNVAAYTEQEEADSQGCVQKTYEEKISVL-QRNL 1745
Query: 317 LKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILS---EKKLGEDEEELSELQ 373
+K K + K +T S ++ + Q ++ ++ + +G +EEL E
Sbjct: 1746 TEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1805
Query: 374 LR--LLALQSASKKWQQKEQQ-----------VMKESKEKLTKTKTVQQKVKTSTKTHSA 420
+ L+ Q K+ + Q V K +EK + ++QK+K
Sbjct: 1806 KKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVR 1865
Query: 421 KKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSN 480
+K + ++ T ++KLQ ++ + + + + + EE+ K K+ LSN
Sbjct: 1866 QK---EVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL--LSN 1920
Query: 481 QEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLD 512
E Q+N + G R + K +R D
Sbjct: 1921 MEAQHNDLEFKLAGAEREKQKLGKEIVRLQKD 1952
Score = 35.0 bits (79), Expect = 0.73
Identities = 69/324 (21%), Positives = 131/324 (40%), Gaps = 53/324 (16%)
Query: 229 LLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNV-SITKDSSKEVAP 287
+L KQ+ E+E KD L + + VQ+ + L ++ V S+T+ ++
Sbjct: 836 ILLTKQVA-EVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLED 894
Query: 288 EEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDS-SQGLQDKEQN 346
K Q +T Q K + + L + + K+++ + LS K D+ ++ + K +N
Sbjct: 895 GNKEQEQTKQILVEK---ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 951
Query: 347 LTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKT 406
+++ +K+ + +E+ E + L Q A K + + + KEK K
Sbjct: 952 QEKKM--------EKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKM 1003
Query: 407 VQQKVKTSTKTHSA-KKVSTTAKQALRK----------QQTKAW-KKLQQQKE------- 447
++ S A ++ T K+ + W KKL QQ E
Sbjct: 1004 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Query: 448 ---QERQKEEDQRKQ------AEEEERRK-----REEEIRKIRDLSNQEEQYNRFMKLVG 493
QE+++E + KQ E+EE K +EE +++ L+ +EQ + V
Sbjct: 1064 IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVN 1123
Query: 494 G------KRRSRSKSSDPDLRRSL 511
K ++ + + DL +SL
Sbjct: 1124 SLAQDETKLKAHLEKLEVDLNKSL 1147
Score = 34.3 bits (77), Expect = 1.2
Identities = 77/436 (17%), Positives = 171/436 (39%), Gaps = 71/436 (16%)
Query: 739 KEARRTAEQASKPKVPPKS--------EKENDPLRTPEALPEEKKIEYRLLKEEIA---- 786
++ R+ +E SK K + EK N L E+K +E++ L EE+A
Sbjct: 1166 EDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLSEELAIQLD 1218
Query: 787 ----NREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMK 842
E K+++L SSS N+ + RI+ + T + L + +
Sbjct: 1219 ICCKKTEALLEAKTNELINISSSKTNAI-----LSRISHCQHRTTKVKEALLIKTCTVSE 1273
Query: 843 DESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQR 902
E+ L+ L +++ S + A ++ + Q+++ + + + LQ++ QQ
Sbjct: 1274 LEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQA 1333
Query: 903 VTIKKALTLKYGEELA---RAKAVASKEIGKRKLEQDRFG---PNKMMRLDSS------- 949
+ K++ + +EL+ A + +E+ ++K+E + ++L +S
Sbjct: 1334 ASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKE 1393
Query: 950 -PVSSPRKH---------------SAELIAMEKRRLQKLEY--EYALKIQKLKEARALKA 991
+SS RK S ++ + K ++ LE +++ K + K+ +
Sbjct: 1394 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRF 1453
Query: 992 KEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFLESN 1051
+ QN ++ + E + D + L + ++ + + L G + + +
Sbjct: 1454 TQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKE 1513
Query: 1052 YFTKPNLKHTDTANKECINKLNKNTVEKPELFLGLKIGELQKLYSKADSLKQLILKTTTG 1111
+ LK E + + + T+E L E+ K Y++ ++
Sbjct: 1514 SNLETELKSQTARIMELEDHITQKTIEIESL------NEVLKNYNQQKDIEH------KE 1561
Query: 1112 ITEKVLHGQEISVDVD 1127
+ +K+ H QE+ + D
Sbjct: 1562 LVQKLQHFQELGEEKD 1577
Score = 32.3 bits (72), Expect = 4.7
Identities = 55/296 (18%), Positives = 126/296 (42%), Gaps = 36/296 (12%)
Query: 199 SSKSFGRSPSRKQNY-SSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV 257
S +S RSP ++ + SS E+ V + + L ++ L+ + D + S+ E++
Sbjct: 71 SVESLFRSPIKESLFRSSSKESLVRTSSRESL---NRLDLDSSTASFDPPSDMDSEAEDL 127
Query: 258 QEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRL 317
+ +LN E + + + ++ + A+++ L +K +L
Sbjct: 128 VGNSDSLNKEQL-----IQRLRRMERSLSSYRGKYSELVTAYQM--------LQREKKKL 174
Query: 318 KKVKDGAKPLSLK--SDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLR 375
+ + ++ SL+ ++ + Q Q +++L S L E ++ +S LQ +
Sbjct: 175 QGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDAS-------LEEKDQYISVLQTQ 227
Query: 376 LLALQSASKKWQQ-----KEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQA 430
+ L+ + K ++ E TK + + + + ++ K T +Q
Sbjct: 228 VSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQR 287
Query: 431 LRKQQT---KAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEE 483
+++Q+ + + +Q KEQ + K+A +E+ +R +E+ KI+DL E+
Sbjct: 288 VKRQENLLKRCKETIQSHKEQCTLLTSE--KEALQEQLDERLQELEKIKDLHMAEK 341
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/266 (20%), Positives = 125/266 (46%), Gaps = 33/266 (12%)
Query: 242 INKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKT--QVKTFQAF 299
+N+ ++ + +EE +QE E++ + I + K EEK Q + +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQ------EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ 344
Query: 300 ELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSE 359
E K RQ+ + + ++++ ++ K + + + +Q++E+ + R+ E
Sbjct: 345 EDKMWRQEEKIREQEEKIREQEE--KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 360 K-----------------KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT 402
K K+ E EEE+ + ++ L+ + ++K ++V ++ +E+
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
K + ++K++ + ++ T ++ L KQ+ K W++ ++ QE + E + K E+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 463 EERRKREEEIRKIRD----LSNQEEQ 484
EE+ +R+EE K+R+ L QEE+
Sbjct: 523 EEKMQRQEE--KMREQEVRLWQQEEK 546
Score = 60.5 bits (145), Expect = 2e-08
Identities = 61/317 (19%), Positives = 145/317 (45%), Gaps = 36/317 (11%)
Query: 233 KQIQLELECINKDEKL-----ALSSKEENVQE-DPKTLNFEDQTSTDNVSITKDSSKEVA 286
K + EL+ ++EK+ + +EE ++E + K E++ I + K
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 287 PEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQN 346
EEK + Q +++ +++ +K R ++ K K + + + ++++E+
Sbjct: 372 QEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Query: 347 LTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKT 406
+ R+ L E+ + + EE+L E++ ++ Q +K Q++E+++ ++ + K +
Sbjct: 429 MWRQEEKIREL-EEMMQDQEEKLREVEEKM---QEEEEKMQEQEEKIQRQEE----KIQE 480
Query: 407 VQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEE--- 463
++K K ++ ++ + +Q+ K W++ ++ +EQE + + + K E+E
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 464 ---ERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDL------------R 508
E + +E+E+R +++L + + + +L+GG R P L
Sbjct: 541 WQQEEKMQEQEVR-LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA 599
Query: 509 RSLDKQPTDSGGGIYQY 525
+SL +Q G + QY
Sbjct: 600 QSLQQQQDHYRGHLQQY 616
Score = 48.1 bits (113), Expect = 8e-05
Identities = 65/285 (22%), Positives = 133/285 (46%), Gaps = 33/285 (11%)
Query: 233 KQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQ 292
K++ ++ + E A E ++ E+ TL+F D I K + + AP +
Sbjct: 151 KRVVIKKPWLRLGEVTAQKRPENSLLEE--TLHF-DHAVRMGTYIEKLTKERDAPSLELY 207
Query: 293 VKTFQAFELKP----LRQKLTL-PGDKNRLK-KVKDGAKPLSLKSDTTDSSQGLQDKEQN 346
T ELK L++KL L +K+ ++ VKD + L ++ Q LQ +
Sbjct: 208 RNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE-RAQLLLPQQQLQVEADR 266
Query: 347 LTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESK--EKLTKT 404
L + + + + ++ E+E LL Q K W+Q+E+ +E K E+ K
Sbjct: 267 LGKELQSVSAKLQAQVEENE------LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320
Query: 405 KTVQQKV-KTSTKTHSAKKVSTTAKQALRKQQTKAWK---KLQQQKEQERQKEE----DQ 456
+ ++K+ + K H + + +R+Q+ K W+ K+++Q+E+ R++EE +
Sbjct: 321 REQEEKMWRQEEKMHEQE-------EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 457 RKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSK 501
K E++E+ + +EE ++ +E++ R K+ +++ R +
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Score = 42.4 bits (98), Expect = 0.005
Identities = 62/260 (23%), Positives = 114/260 (43%), Gaps = 43/260 (16%)
Query: 243 NKDEKLALSSKEENVQEDPKTLNF---EDQTSTD-NVSITKDSSKEVAP-----EEKTQV 293
++D+ L S + +E K + F +D+ D VS K +S EV +EK
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNE 144
Query: 294 KTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPL-SLKSDTTDSSQGLQ--------DKE 344
K + R+++ + RL +V +P SL +T ++ KE
Sbjct: 145 KNYT------FRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKE 198
Query: 345 QN-----LTRRISTSDILSEK------KLGEDEEELSELQLRLLALQSASKKWQQ--KEQ 391
++ L R T + L EK KL E E SE+QL + L+ ++ Q +Q
Sbjct: 199 RDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQ 258
Query: 392 QVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQ 451
Q+ E+ + ++V K++ + + + ++Q+ K W++ ++ +EQE +
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLN------QQQEEKMWRQEEKIQEQEEK 312
Query: 452 KEEDQRKQAEEEERRKREEE 471
E + K E+EE+ R+EE
Sbjct: 313 MCEQELKIREQEEKMWRQEE 332
Score = 35.4 bits (80), Expect = 0.56
Identities = 77/415 (18%), Positives = 177/415 (42%), Gaps = 35/415 (8%)
Query: 734 LESMIKEARRTAEQASKPKVPPKSEKE-NDPLRTPEALPEEKKIEYRLLKEEIANR---- 788
+E + KE + + + + + KE N L+ L E +K E +L +++ +
Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 789 -----EKQRLIKSDQL-KTSSSSPANSDVEIDGIGRIAMVTKQVTDA----ESKLKKHRI 838
++Q +++D+L K S A +++ ++ +Q + E K+++
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 839 LLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHR 898
+ + E ++ ++ +++E + E KI + +++ E+ + +++ +E++ R
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 899 VQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHS 958
++++ + + EE+ R + ++ KR ++ + K MR + R+
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQDEKI---REQE 426
Query: 959 AELIAMEK--RRLQKLEYEYALKIQKLKE---ARALKAKEQ----QNISPVVEEEPEFSL 1009
E+ E+ R L+++ + K+++++E K +EQ Q ++E+ E +
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 1010 PQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECI 1069
Q L L Q++ + EE E E+ + E + ++ + +
Sbjct: 487 RQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 1070 NKLNKNTVEKPELFLGL-KIGELQKLYSKA--DSLKQLILKTTTGITEKVLHGQE 1121
K+ + V EL L K+G+ +L A +S Q L T T I + L QE
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR-LPTLTPILQVELKSQE 598
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/266 (20%), Positives = 125/266 (46%), Gaps = 33/266 (12%)
Query: 242 INKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKT--QVKTFQAF 299
+N+ ++ + +EE +QE E++ + I + K EEK Q + +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQ------EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ 344
Query: 300 ELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSE 359
E K RQ+ + + ++++ ++ K + + + +Q++E+ + R+ E
Sbjct: 345 EDKMWRQEEKIREQEEKIREQEE--KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 360 K-----------------KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT 402
K K+ E EEE+ + ++ L+ + ++K ++V ++ +E+
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
K + ++K++ + ++ T ++ L KQ+ K W++ ++ QE + E + K E+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 463 EERRKREEEIRKIRD----LSNQEEQ 484
EE+ +R+EE K+R+ L QEE+
Sbjct: 523 EEKMQRQEE--KMREQEVRLWQQEEK 546
Score = 60.5 bits (145), Expect = 2e-08
Identities = 61/317 (19%), Positives = 145/317 (45%), Gaps = 36/317 (11%)
Query: 233 KQIQLELECINKDEKL-----ALSSKEENVQE-DPKTLNFEDQTSTDNVSITKDSSKEVA 286
K + EL+ ++EK+ + +EE ++E + K E++ I + K
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 287 PEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQN 346
EEK + Q +++ +++ +K R ++ K K + + + ++++E+
Sbjct: 372 QEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Query: 347 LTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKT 406
+ R+ L E+ + + EE+L E++ ++ Q +K Q++E+++ ++ + K +
Sbjct: 429 MWRQEEKIREL-EEMMQDQEEKLREVEEKM---QEEEEKMQEQEEKIQRQEE----KIQE 480
Query: 407 VQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEE--- 463
++K K ++ ++ + +Q+ K W++ ++ +EQE + + + K E+E
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 464 ---ERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDL------------R 508
E + +E+E+R +++L + + + +L+GG R P L
Sbjct: 541 WQQEEKMQEQEVR-LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA 599
Query: 509 RSLDKQPTDSGGGIYQY 525
+SL +Q G + QY
Sbjct: 600 QSLQQQQDHYRGHLQQY 616
Score = 44.7 bits (104), Expect = 0.001
Identities = 67/320 (20%), Positives = 144/320 (45%), Gaps = 49/320 (15%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEETF----EDLLLKYKQIQLELECINKDEKLALSSK 253
KSS + ++NY+ + +++ + E K + L E ++ D + + +
Sbjct: 132 KSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTY 191
Query: 254 EENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTL-PG 312
E + ++ L+ E +T IT + KE E L++KL L
Sbjct: 192 IEKLTKERDALSLELYRNT----ITDEELKEKNAE---------------LQEKLRLVES 232
Query: 313 DKNRLK-KVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSE 371
+K+ ++ VKD + L ++ Q LQ + L + + + + ++ E+E
Sbjct: 233 EKSEIQLNVKDLKRKLE-RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENE----- 286
Query: 372 LQLRLLALQSASKKWQQKEQQVMKESK--EKLTKTKTVQQKV-KTSTKTHSAKKVSTTAK 428
LL Q K W+Q+E+ +E K E+ K + ++K+ + K H +
Sbjct: 287 -LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE------- 338
Query: 429 QALRKQQTKAWK---KLQQQKEQERQKEE----DQRKQAEEEERRKREEEIRKIRDLSNQ 481
+ +R+Q+ K W+ K+++Q+E+ R++EE + K E++E+ + +EE ++ +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398
Query: 482 EEQYNRFMKLVGGKRRSRSK 501
E++ R K+ +++ R +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQ 418
Score = 42.4 bits (98), Expect = 0.005
Identities = 62/260 (23%), Positives = 114/260 (43%), Gaps = 43/260 (16%)
Query: 243 NKDEKLALSSKEENVQEDPKTLNF---EDQTSTD-NVSITKDSSKEVAP-----EEKTQV 293
++D+ L S + +E K + F +D+ D VS K +S EV +EK
Sbjct: 85 DEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNE 144
Query: 294 KTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPL-SLKSDTTDSSQGLQ--------DKE 344
K + R+++ + RL +V +P SL +T ++ KE
Sbjct: 145 KNYT------FRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKE 198
Query: 345 QN-----LTRRISTSDILSEK------KLGEDEEELSELQLRLLALQSASKKWQQ--KEQ 391
++ L R T + L EK KL E E SE+QL + L+ ++ Q +Q
Sbjct: 199 RDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQ 258
Query: 392 QVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQ 451
Q+ E+ + ++V K++ + + + ++Q+ K W++ ++ +EQE +
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLN------QQQEEKMWRQEEKIQEQEEK 312
Query: 452 KEEDQRKQAEEEERRKREEE 471
E + K E+EE+ R+EE
Sbjct: 313 MCEQELKIREQEEKMWRQEE 332
Score = 40.8 bits (94), Expect = 0.013
Identities = 48/217 (22%), Positives = 95/217 (43%), Gaps = 18/217 (8%)
Query: 306 QKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTR-RISTSDILSEKKLGE 364
+KLT D L+ ++ LK + + L+ E + +++ D+ ++KL
Sbjct: 193 EKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDL--KRKLER 250
Query: 365 DEEELSELQLRLLA------LQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH 418
+ L + QL++ A LQS S K Q QV + L + ++ + K
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQA---QVEENELWNLLNQQQEEKMWRQEEKIQ 307
Query: 419 SAKKVSTTAKQALRKQQTKAWK---KLQQQKEQERQKEEDQRKQAE---EEERRKREEEI 472
++ + +R+Q+ K W+ K+ +Q+E+ R++E+ +Q E E+E + RE+E
Sbjct: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
Query: 473 RKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRR 509
+ R EQ + + R K + + +R
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR 404
Score = 35.4 bits (80), Expect = 0.56
Identities = 77/415 (18%), Positives = 177/415 (42%), Gaps = 35/415 (8%)
Query: 734 LESMIKEARRTAEQASKPKVPPKSEKE-NDPLRTPEALPEEKKIEYRLLKEEIANR---- 788
+E + KE + + + + + KE N L+ L E +K E +L +++ +
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 789 -----EKQRLIKSDQL-KTSSSSPANSDVEIDGIGRIAMVTKQVTDA----ESKLKKHRI 838
++Q +++D+L K S A +++ ++ +Q + E K+++
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 839 LLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHR 898
+ + E ++ ++ +++E + E KI + +++ E+ + +++ +E++ R
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 899 VQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHS 958
++++ + + EE+ R + ++ KR ++ + K MR + R+
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQDEKI---REQE 426
Query: 959 AELIAMEK--RRLQKLEYEYALKIQKLKE---ARALKAKEQ----QNISPVVEEEPEFSL 1009
E+ E+ R L+++ + K+++++E K +EQ Q ++E+ E +
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 1010 PQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECI 1069
Q L L Q++ + EE E E+ + E + ++ + +
Sbjct: 487 RQEKL--LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 1070 NKLNKNTVEKPELFLGL-KIGELQKLYSKA--DSLKQLILKTTTGITEKVLHGQE 1121
K+ + V EL L K+G+ +L A +S Q L T T I + L QE
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR-LPTLTPILQVELKSQE 598
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/272 (23%), Positives = 123/272 (45%), Gaps = 35/272 (12%)
Query: 254 EENVQEDPKTLNFE----DQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLT 309
+E+V D +NF ++ + ++ KE+ +EK +K + E K +++
Sbjct: 146 DEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEE-- 203
Query: 310 LPGDKNR---LKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDE 366
++ R +K+ K K L + +Q +EQ+ ++ E+K+ +++
Sbjct: 204 ---EEKRHCWMKQFKVEKKKL----------ENIQKQEQDKMN----DELYKEEKIWKEK 246
Query: 367 EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSA-KKVST 425
+ E +R L LQ ++ + K+QQ KE L + K++ K A +K
Sbjct: 247 FKQHEEYIRNLHLQMEEERTRFKDQQE-KEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 426 TAKQALRKQQTKAWKKLQQQKEQE---RQKEEDQRKQAEEEERRKREEEIRKIRDLSNQE 482
K+ + ++ KA Q+ KE+E RQKEE+ RK+ EEE+R K E + +K + +E
Sbjct: 306 IIKEQIESKKRKA----QEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRRE 361
Query: 483 EQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
++Y +V +R LR +Q
Sbjct: 362 KEYEEKKNIVKQEREQLISKEKIILREDASQQ 393
Score = 47.4 bits (111), Expect = 1e-04
Identities = 61/266 (22%), Positives = 119/266 (44%), Gaps = 24/266 (9%)
Query: 197 RKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEEN 256
RK K R R++ Y K +N V++ E L+ K K I E + ++L +SS +
Sbjct: 349 RKKQKEEERK-RREKEYEEK-KNIVKQEREQLISKEKIILRE----DASQQLIISSALKK 402
Query: 257 VQEDPKTLNFEDQTSTDNVSITKDSSKEVAP-EEKTQVKTFQAFELKPLRQKLTLPGDKN 315
+ K L+ ED S D I K+ E + +E + + +K + T+ +
Sbjct: 403 SGYNNKHLSLED-ISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESI 461
Query: 316 RLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLR 375
++K + S+ S T + +++K +NL ++ + +++ +++ E+ + +EL
Sbjct: 462 QVKLKE------SISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELG-- 513
Query: 376 LLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKV---KTSTKTHSAKKVSTTAKQALR 432
++ K KEQ ++E K K + + + V T KT + +
Sbjct: 514 -----NSDLKGNLKEQFPLQELKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKT 568
Query: 433 KQQTKAWKKLQQQKEQERQKEEDQRK 458
++ K K QQ+K Q+ +KEE Q +
Sbjct: 569 NEEQKIIKDNQQKKIQKVEKEEIQEQ 594
Score = 46.6 bits (109), Expect = 2e-04
Identities = 70/317 (22%), Positives = 137/317 (43%), Gaps = 27/317 (8%)
Query: 739 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKI-----EYRLLKEEIANRE--KQ 791
+E R+ E+ + K K +KE + R + E+K I E + KE+I RE Q
Sbjct: 333 EENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQ 392
Query: 792 RLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLV 851
+LI S LK S + + +E D + K + D SK ++ +L + +ES +K V
Sbjct: 393 QLIISSALKKSGYNNKHLSLE-DISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENV 451
Query: 852 QQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTL 911
++ KES++ + K + ++ + A K+ N KK + Q+R
Sbjct: 452 DRQTILKESIQ-VKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQER--------- 501
Query: 912 KYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQK 971
KY E + + ++ EQ P + ++ D+ KH +K ++
Sbjct: 502 KY-ENTDNKTELGNSDLKGNLKEQ---FPLQELKSDAQKEEKIMKHVINENTGQKTQIIL 557
Query: 972 LEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDV 1031
+ +++ +E + +K +Q+ I V +EE + Q L +D L + ++ +
Sbjct: 558 GHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQ---EQNGLLYKDKDTLVISVKQRSL 614
Query: 1032 DDEILSGSSRERRRSFL 1048
+ S +S++ R + +
Sbjct: 615 --SLTSENSKDVRENVI 629
Score = 39.3 bits (90), Expect = 0.039
Identities = 61/305 (20%), Positives = 128/305 (41%), Gaps = 47/305 (15%)
Query: 236 QLELECINKDEKLALSSKE-ENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVK 294
+L+ E + +KL++SS E E+++ D K+ D + TD+V + PE
Sbjct: 7 KLKAEIEAELDKLSISSLEKEDIESDAKSETQSDDSDTDSVEL---------PESVLHCI 57
Query: 295 TFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQG-LQDKEQNLTRRIST 353
KNR K V++ +D S G + + +L +ST
Sbjct: 58 NII----------------KNRSKAVEELILQDLEDTDILSCSYGAVSNNHMHLRTGLST 101
Query: 354 SDILSEKKLGEDEEELSELQLRLLALQSASKKWQQK--------EQQVMKESKEKLTKTK 405
S ++L + E+ + + A+ + + ++ V+ + +
Sbjct: 102 EYEESSEQLIKILSEIEKEEFMRSKTDCATPDFVPEPSPHDLPMDEHVLPDDADINFGYC 161
Query: 406 TVQQKVKTSTKT--HSAKKVSTTAKQALRKQQTKAWKKLQQQKEQ----------ERQKE 453
V++K + S + K++ KQ L+ Q+ + K+ Q+++E+ E++K
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221
Query: 454 EDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDK 513
E+ +KQ +++ + +E + ++ Q E+Y R + L + R+R K + SL K
Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281
Query: 514 QPTDS 518
Q ++
Sbjct: 282 QQNNA 286
Score = 33.5 bits (75), Expect = 2.1
Identities = 40/208 (19%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 214 SSKNENCVEETF--EDLLLKYKQ------IQLELECINKDEKLALSS-KEENVQEDPKTL 264
S+ EN +T E + +K K+ I + + K+E LA EE V+++ K
Sbjct: 445 SNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYE 504
Query: 265 NFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGA 324
N +++T N + K + KE P + ++K+ E K ++ + + + ++ G
Sbjct: 505 NTDNKTELGNSDL-KGNLKEQFPLQ--ELKSDAQKEEKIMKHVIN--ENTGQKTQIILGH 559
Query: 325 KPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASK 384
+ T + + ++D +Q +++ +I + L +++ + ++ +L S+
Sbjct: 560 NQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRSLSLTSE 619
Query: 385 KWQQKEQQVMKESKEKLTKTKTVQQKVK 412
+ + V+ + KE +K+K +++ K
Sbjct: 620 NSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/272 (23%), Positives = 123/272 (45%), Gaps = 35/272 (12%)
Query: 254 EENVQEDPKTLNFE----DQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLT 309
+E+V D +NF ++ + ++ KE+ +EK +K + E K +++
Sbjct: 146 DEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEE-- 203
Query: 310 LPGDKNR---LKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDE 366
++ R +K+ K K L + +Q +EQ+ ++ E+K+ +++
Sbjct: 204 ---EEKRHCWMKQFKVEKKKL----------ENIQKQEQDKMN----DELYKEEKIWKEK 246
Query: 367 EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSA-KKVST 425
+ E +R L LQ ++ + K+QQ KE L + K++ K A +K
Sbjct: 247 FKQHEEYIRNLHLQMEEERTRFKDQQE-KEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 426 TAKQALRKQQTKAWKKLQQQKEQE---RQKEEDQRKQAEEEERRKREEEIRKIRDLSNQE 482
K+ + ++ KA Q+ KE+E RQKEE+ RK+ EEE+R K E + +K + +E
Sbjct: 306 IIKEQIESKKRKA----QEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRRE 361
Query: 483 EQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
++Y +V +R LR +Q
Sbjct: 362 KEYEEKKNIVKQEREQLISKEKIILREDASQQ 393
Score = 47.4 bits (111), Expect = 1e-04
Identities = 61/266 (22%), Positives = 119/266 (44%), Gaps = 24/266 (9%)
Query: 197 RKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEEN 256
RK K R R++ Y K +N V++ E L+ K K I E + ++L +SS +
Sbjct: 349 RKKQKEEERK-RREKEYEEK-KNIVKQEREQLISKEKIILRE----DASQQLIISSALKK 402
Query: 257 VQEDPKTLNFEDQTSTDNVSITKDSSKEVAP-EEKTQVKTFQAFELKPLRQKLTLPGDKN 315
+ K L+ ED S D I K+ E + +E + + +K + T+ +
Sbjct: 403 SGYNNKHLSLED-ISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESI 461
Query: 316 RLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLR 375
++K + S+ S T + +++K +NL ++ + +++ +++ E+ + +EL
Sbjct: 462 QVKLKE------SISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELG-- 513
Query: 376 LLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKV---KTSTKTHSAKKVSTTAKQALR 432
++ K KEQ ++E K K + + + V T KT + +
Sbjct: 514 -----NSDLKGNLKEQFPLQELKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKT 568
Query: 433 KQQTKAWKKLQQQKEQERQKEEDQRK 458
++ K K QQ+K Q+ +KEE Q +
Sbjct: 569 NEEQKIIKDNQQKKIQKVEKEEIQEQ 594
Score = 46.6 bits (109), Expect = 2e-04
Identities = 70/317 (22%), Positives = 137/317 (43%), Gaps = 27/317 (8%)
Query: 739 KEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKI-----EYRLLKEEIANRE--KQ 791
+E R+ E+ + K K +KE + R + E+K I E + KE+I RE Q
Sbjct: 333 EENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQ 392
Query: 792 RLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLV 851
+LI S LK S + + +E D + K + D SK ++ +L + +ES +K V
Sbjct: 393 QLIISSALKKSGYNNKHLSLE-DISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENV 451
Query: 852 QQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTL 911
++ KES++ + K + ++ + A K+ N KK + Q+R
Sbjct: 452 DRQTILKESIQ-VKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQER--------- 501
Query: 912 KYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQK 971
KY E + + ++ EQ P + ++ D+ KH +K ++
Sbjct: 502 KY-ENTDNKTELGNSDLKGNLKEQ---FPLQELKSDAQKEEKIMKHVINENTGQKTQIIL 557
Query: 972 LEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDV 1031
+ +++ +E + +K +Q+ I V +EE + Q L +D L + ++ +
Sbjct: 558 GHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQ---EQNGLLYKDKDTLVISVKQRSL 614
Query: 1032 DDEILSGSSRERRRSFL 1048
+ S +S++ R + +
Sbjct: 615 --SLTSENSKDVRENVI 629
Score = 39.3 bits (90), Expect = 0.039
Identities = 61/305 (20%), Positives = 128/305 (41%), Gaps = 47/305 (15%)
Query: 236 QLELECINKDEKLALSSKE-ENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVK 294
+L+ E + +KL++SS E E+++ D K+ D + TD+V + PE
Sbjct: 7 KLKAEIEAELDKLSISSLEKEDIESDAKSETQSDDSDTDSVEL---------PESVLHCI 57
Query: 295 TFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQG-LQDKEQNLTRRIST 353
KNR K V++ +D S G + + +L +ST
Sbjct: 58 NII----------------KNRSKAVEELILQDLEDTDILSCSYGAVSNNHMHLRTGLST 101
Query: 354 SDILSEKKLGEDEEELSELQLRLLALQSASKKWQQK--------EQQVMKESKEKLTKTK 405
S ++L + E+ + + A+ + + ++ V+ + +
Sbjct: 102 EYEESSEQLIKILSEIEKEEFMRSKTDCATPDFVPEPSPHDLPMDEHVLPDDADINFGYC 161
Query: 406 TVQQKVKTSTKT--HSAKKVSTTAKQALRKQQTKAWKKLQQQKEQ----------ERQKE 453
V++K + S + K++ KQ L+ Q+ + K+ Q+++E+ E++K
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221
Query: 454 EDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDK 513
E+ +KQ +++ + +E + ++ Q E+Y R + L + R+R K + SL K
Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281
Query: 514 QPTDS 518
Q ++
Sbjct: 282 QQNNA 286
Score = 33.5 bits (75), Expect = 2.1
Identities = 40/208 (19%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 214 SSKNENCVEETF--EDLLLKYKQ------IQLELECINKDEKLALSS-KEENVQEDPKTL 264
S+ EN +T E + +K K+ I + + K+E LA EE V+++ K
Sbjct: 445 SNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYE 504
Query: 265 NFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGA 324
N +++T N + K + KE P + ++K+ E K ++ + + + ++ G
Sbjct: 505 NTDNKTELGNSDL-KGNLKEQFPLQ--ELKSDAQKEEKIMKHVIN--ENTGQKTQIILGH 559
Query: 325 KPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASK 384
+ T + + ++D +Q +++ +I + L +++ + ++ +L S+
Sbjct: 560 NQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRSLSLTSE 619
Query: 385 KWQQKEQQVMKESKEKLTKTKTVQQKVK 412
+ + V+ + KE +K+K +++ K
Sbjct: 620 NSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 62.0 bits (149), Expect = 6e-09
Identities = 54/283 (19%), Positives = 137/283 (48%), Gaps = 24/283 (8%)
Query: 205 RSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTL 264
R K + K E+ E+ ++ ++ + E E ++ + +EE ++E K +
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 265 NFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGA 324
+++ + I ++ ++ E Q + + E + RQK + ++ +++K ++
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKMH-EQEKIRKQEE-- 495
Query: 325 KPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASK 384
K + D + ++++E+ + R+ E+K+ E EE++ E + ++ +
Sbjct: 496 KVWRQEEKMHDQEEKIREQEEKMWRQ--------EEKIREQEEKIREQEEKI----REQE 543
Query: 385 KWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQ 444
+ Q++++ M E +EK+ + + ++++ + K ++ K+ +R+Q+ K W++ ++
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEE---KIREQEEKIREQKEKIREQEEKIWEQEEK 600
Query: 445 QKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
+EQE +E + K E+EE+ +EE + QEE+ R
Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEE-----KMQEQEEKMRR 638
Score = 60.1 bits (144), Expect = 2e-08
Identities = 57/264 (21%), Positives = 133/264 (50%), Gaps = 29/264 (10%)
Query: 228 LLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAP 287
LLL +Q+Q E + + K E ++S+K + E+ + N +Q + + ++ +E
Sbjct: 256 LLLPQQQLQAEADHLGK-ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-- 312
Query: 288 EEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
EEK Q Q +++ +K+ +K R ++ K ++ + + +KE+ +
Sbjct: 313 EEKIQE---QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKM 365
Query: 348 TRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTV 407
R E+ + E EE++ EL+ K +Q++ + +E +++ K +
Sbjct: 366 RRL--------EEMMWEKEEKIRELE---------EKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 408 QQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRK 467
+++ + K ++ ++ +R+Q+ K W++ ++ EQE+ +EE++R+ E+EE +
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ--EQEEMWR 466
Query: 468 REEEIRKIRDLSNQEEQYNRFMKL 491
+EE+IR+ ++ Q+E+ + K+
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKI 490
Score = 56.2 bits (134), Expect = 3e-07
Identities = 51/303 (16%), Positives = 144/303 (47%), Gaps = 14/303 (4%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV 257
+ ++ + R +++ + E ++E E + + ++I+ + E I + E+ +E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 258 QEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRL 317
+++ K E+ + + EEK + + E + +R++ ++ ++
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
Query: 318 ----KKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDE--EELSE 371
K+ + AK + + + ++++E+ + R+ I ++K+ E+E +E E
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHEQEKIREEEKRQEQEE 463
Query: 372 LQLRLLALQSASKKWQQKE----QQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTA 427
+ + ++ + W+QKE Q+ +++ +EK+ + + ++ K ++
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE--EKMHDQEEKIREQEEKMWRQ 521
Query: 428 KQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNR 487
++ +R+Q+ K ++ ++ +EQE +E + K E+EE+ + +E++R+ + ++E+ R
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 488 FMK 490
K
Sbjct: 582 EQK 584
Score = 54.3 bits (129), Expect = 1e-06
Identities = 58/288 (20%), Positives = 132/288 (45%), Gaps = 34/288 (11%)
Query: 226 EDLLLKYKQIQLEL--ECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITK---D 280
E+L + + LEL I +E L K +QE + + E NV K +
Sbjct: 196 EELTKERDALSLELYRNTITDEE---LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252
Query: 281 SSKEVAPEEKTQVKTFQ-AFELKPLRQKLTLPGDKNRL----------------KKVKDG 323
+K + P+++ Q + EL+ + KL ++N L +K+++
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 312
Query: 324 AKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSAS 383
+ + + + + +++ RR E+K+ EE + E + ++ L+
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 384 KKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQ 443
W+++E+ ++E +EK+ + + ++++ + K +K+ K+ ++Q+ K W++ +
Sbjct: 373 --WEKEEK--IRELEEKMHEQEKIREQEE---KRQEEEKIREQEKR--QEQEAKMWRQEE 423
Query: 444 QQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKL 491
+ +EQE + E ++K +EE+ +E+IR+ QEE + + K+
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Score = 52.8 bits (125), Expect = 3e-06
Identities = 53/222 (23%), Positives = 108/222 (48%), Gaps = 28/222 (12%)
Query: 288 EEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
E + QV T + + ++ L ++ +K+++ A+ L S DS + + EQ L
Sbjct: 124 ELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI--SRLHDSWKFAGELEQAL 181
Query: 348 TRRISTSDILSEKKLGEDEEELSELQLRLLA-------LQSASKKWQQKEQQV------- 393
+ ++T +++ + E +E L L L L+ + K Q+K Q V
Sbjct: 182 SA-VATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 394 ---MKESKEKLTKTKTV--QQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKE- 447
+KE K KL + K + QQ+++ + S +AK + ++ + W +L QQ+E
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 448 -----QERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
+E+ +E +++ Q +EE+ R++EE+IR+ + ++E+
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
Score = 51.6 bits (122), Expect = 8e-06
Identities = 50/284 (17%), Positives = 139/284 (48%), Gaps = 24/284 (8%)
Query: 191 REPSPPRKSSKSFGRSPSRKQNYSS--KNENCVEETFEDLLLKYKQIQLELECINKDEKL 248
RE R+ + R++ + + E + E E + + K++ + E I++ EK+
Sbjct: 393 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 452
Query: 249 ALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKL 308
+EE +++ + + +++ + I + K + +EK + + E K RQ+
Sbjct: 453 ----REEEKRQEQEEMWRQEEKIREQEEIWRQKEK-MHEQEKIRKQ-----EEKVWRQEE 502
Query: 309 TLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEE 368
+ + ++++ ++ K + + + ++++E+ + + E+K+GE EE+
Sbjct: 503 KMHDQEEKIREQEE--KMWRQEEKIREQEEKIREQEEKIREQEEMMQE-QEEKMGEQEEK 559
Query: 369 LSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKV-KTSTKTHSAKKVSTTA 427
+ E + ++ +K +++E+++ +E KEK+ + ++K+ + K +++
Sbjct: 560 MQEQE----KMRRQEEKIREQEEKI-REQKEKIREQ---EEKIWEQEEKIREQEEMMQEQ 611
Query: 428 KQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEE 471
++ + +Q+ K ++ ++ +EQE + + K E+E R +++EE
Sbjct: 612 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 655
Score = 50.1 bits (118), Expect = 2e-05
Identities = 58/297 (19%), Positives = 138/297 (46%), Gaps = 30/297 (10%)
Query: 234 QIQLELECINKDEKLALSSKEENVQE-DPKTLNFEDQTSTDNVSITKDSSKE----VAPE 288
+++ L + +K A EE +E D +L T TD K++ + +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 289 EKTQVK-TFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
EK++++ + + K R KL LP ++++ A L + + + Q +E L
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQ-----QQLQAEADHLGKELQSVSAKLQAQVEENEL 290
Query: 348 TRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTV 407
R++ E+K+ EE++ E + ++ Q +K +++E+++ +E +EK+ + + +
Sbjct: 291 WNRLNQQQ---EEKMWRQEEKIQEWEEKI---QEQEEKIREQEEKI-REQEEKMRRQEEM 343
Query: 408 QQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKE-------QERQKEEDQRKQA 460
+ + K +++ ++ +R+ + W+K ++ +E QE+ +E+++++Q
Sbjct: 344 MWEKEE--KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Query: 461 EE---EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQ 514
EE E+ +++E+E + R EQ + + R K + + R +K+
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
Score = 37.7 bits (86), Expect = 0.11
Identities = 62/339 (18%), Positives = 147/339 (43%), Gaps = 30/339 (8%)
Query: 696 RTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPP 755
R +SL +++ + + + E + S ++ +KE +R E+A
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 756 KSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDG 815
+ + E D L E K++ ++ + E+ NR Q+ + +++
Sbjct: 262 QLQAEADHLGK-ELQSVSAKLQAQVEENELWNRLNQQ--QEEKMWRQEE----------- 307
Query: 816 IGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQL 875
+I +++ + E K+++ + + E ++ + +K+E +R E + + E++
Sbjct: 308 --KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 876 QATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGK--RKL 933
+ E+++ +++L+E++H ++ I++ + EE R + ++ K R+
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEK---IREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 934 EQDRFGPNKMMRLDSSPVSSPRK-HSAELIAMEKRRLQKLE-YEYALKIQKLKEARALKA 991
E+ R K+ + K H E I E++R ++ E + KI++ +E K
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 482
Query: 992 K--EQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEE 1028
K EQ+ I ++E + + +HD Q++ + EE
Sbjct: 483 KMHEQEKIR---KQEEKVWRQEEKMHD--QEEKIREQEE 516
>gi|195947369 junction-mediating and regulatory protein [Homo
sapiens]
Length = 988
Score = 61.6 bits (148), Expect = 7e-09
Identities = 81/348 (23%), Positives = 140/348 (40%), Gaps = 34/348 (9%)
Query: 398 KEKLTKTKTVQ----QKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKE 453
KE++ + +Q QK++ + A++ +AK++ + + + +K Q+R +
Sbjct: 585 KEEMAASAYLQREELQKLQQKARQLEARRGRVSAKKSYLRNKKEICIAKHNEKIQQRTRI 644
Query: 454 EDQ----------RKQAEEEERRKR----EEEIRKIRDLSNQEEQYNRFMKLVGGKRRSR 499
ED+ R++ +EE RK +E R + L +++Y + L + R
Sbjct: 645 EDEYRTHHTVQLKREKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRLA 704
Query: 500 SKSSDPDLRRSLDKQPTDSGGGIYQYDNY-EEVAMDTDSETSSPAPSPVQPPFFSECSLG 558
L + DS + Q + EEV S P + SL
Sbjct: 705 HARRKGAASPVLQEDHCDSLPSVLQVEEKTEEVGEGRVKRGPSQTTEPQSLVQLEDTSL- 763
Query: 559 YFSPAPSLSLPPPPQVSSLPP-LSQPYV----EGLCVSLEPLP-PLPPLPPLPPEDPEQP 612
+ + SLP S LPP +S P + E V++ PLP PLPP PP PP P P
Sbjct: 764 --TQLEATSLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPP 821
Query: 613 PKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSI 672
P PP ++ L ++L + N++ P+ S+ PS + ++S V
Sbjct: 822 PPPPLPVAKDSGPETLEKDLPRKEGNEKRI-PKSASA----PSAHLFDSSQLVSARKKLR 876
Query: 673 VSINTVSQPRIQNPKFHRGPRLPRTVISLPK-HKSVVVTLNDSDDSES 719
+ + + R+ +P L R L K + + D DDS +
Sbjct: 877 KTAEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNN 924
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 61.6 bits (148), Expect = 7e-09
Identities = 167/809 (20%), Positives = 327/809 (40%), Gaps = 125/809 (15%)
Query: 242 INKDEKLALSSKEENVQEDPKTLNFEDQTS-----------TDNVSITKDSSKEVAPEEK 290
++ E+L S +E PK N EDQ S TD VS TK SS+ A
Sbjct: 326 VDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSV 385
Query: 291 TQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRR 350
+V P + + ++ + K L+ + D Q + + +
Sbjct: 386 AKV---------PYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDR-QAVPGRPGPFPSK 435
Query: 351 ISTSDILSEKKLGEDE--EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT--KTKT 406
+D EDE ++ Q + A ++K +++E++ M+E ++ K K
Sbjct: 436 QQVAD--------EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKR 487
Query: 407 VQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERR 466
+ +K+ K S +++ ++ R+++ K+L++++EQER+KE ++ ++ ++E+ +
Sbjct: 488 LDEKLGILEKQPSPEEIREREREKERERE----KELEKEQEQEREKEREKDRERQQEKEK 543
Query: 467 KREEEIRKIRDLSNQEEQ-YNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQY 525
+ E+E K R++ + +Q + ++ K + K + + L+K+ I
Sbjct: 544 ELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPR 603
Query: 526 D-NYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPY 584
+ N E + +SE S +P F + S A + P+ S P
Sbjct: 604 EPNLEPMVEKQESENS--CNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP--RPAV 659
Query: 585 VEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKP 644
+ G + LPP EQ + + ++++++ +L + + P
Sbjct: 660 LSGYFKQFQ-----KSLPPRFQRQQEQMKQQQW--QQQQQQGVLPQTV-----------P 701
Query: 645 EETSSNSDPPSP--PVLNNSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRL--PRTVIS 700
+ SS++ PP P P+ P P+ S+ PR + + PR+ R +
Sbjct: 702 SQPSSSTVPPPPHRPLYQPMQPHPQHLASM-----GFDPRWLMMQSYMDPRMMSGRPAMD 756
Query: 701 LPK-HKSVV--VTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKV---- 753
+P H ++ L D E +S+S E + + AR A S+P++
Sbjct: 757 IPPIHPGMIPPKPLMRRDQMEGSPNSSES-------FEHIARSARDHAISLSEPRMLWGS 809
Query: 754 PPKSEKENDPLRTPEAL--PEEKKIEYRLLKEEIA------NREKQRLIKSDQLKTSSSS 805
P E TP+A PE+ + E L +E+I + + + K+D ++ SS +
Sbjct: 810 DPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEA 869
Query: 806 PANSDVEIDGIGRIAMVTKQVTDAES-----KLKKHRILLMKDESVLKNLVQQEAKKKES 860
+ + V TDA + + + L E + + V+ + +K S
Sbjct: 870 QVQKFLS----RSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERI-SAVESQPSRKRS 924
Query: 861 VRNAEAKITKLTEQLQATEKILNVNRMFLKKL--QEQIHRVQQRVTIKKALTLKYGEELA 918
V + K E Q +E + ++ + + +E I R +++ KK ++ E
Sbjct: 925 VSHGSNHTQKPDE--QRSEPSAGIPKVTSRCIDSKEPIERPEEKP--KKEGFIRSSEGPK 980
Query: 919 RAKAVASKEIGKRKLEQDRFGP----NKMMRLDSSPV--SSPRKHSAELIAMEKRRLQKL 972
K SK + R+GP N+ ++ PV S P K L M++ R Q+
Sbjct: 981 PEKVYKSK-------SETRWGPRPSSNRREEVNDRPVRRSGPIKKPV-LRDMKEEREQRK 1032
Query: 973 EYEYALKIQKLKEARALKAK--EQQNISP 999
E E K +K+ E +K + E++++ P
Sbjct: 1033 EKE-GEKAEKVTEKVVVKPEKTEKKDLPP 1060
Score = 37.4 bits (85), Expect = 0.15
Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 31/149 (20%)
Query: 456 QRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQP 515
Q+K+ ++EERRK+EE++ ++ + N E K RS++ P R KQ
Sbjct: 1689 QQKRLQDEERRKKEEQVIQVWNKKNANE-----------KGRSQTSKLPP---RFAKKQA 1734
Query: 516 TDSGGGIYQYDNYEEVAMDTDSETSSP--APSPVQPPFFSECSLGYFSPAPSLSLPPPPQ 573
T GI Q S S P A +P+ P + +P P+ +L P P
Sbjct: 1735 T----GIQQ----------AQSSASVPPLASAPLPPSTSASVPASTSAPLPA-TLTPVPA 1779
Query: 574 VSSLPPLSQPYVEGLCVSLEPLPPLPPLP 602
+S P + L + P+P P P
Sbjct: 1780 STSAPVPASTLAPVLASTSAPVPASPLAP 1808
Score = 35.4 bits (80), Expect = 0.56
Identities = 58/277 (20%), Positives = 100/277 (36%), Gaps = 38/277 (13%)
Query: 416 KTHSA---KKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEE-----------DQRKQAE 461
KT SA +++S Q RK+ Q+ +++R + D ++ E
Sbjct: 902 KTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIE 961
Query: 462 EEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRS---RSKSSDPDLRRSLD-KQPTD 517
E + ++E + + E+ Y + G R S R + +D +RRS K+P
Sbjct: 962 RPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV- 1020
Query: 518 SGGGIYQYDNYEEVAMDTDSETSSPAPSPV--QPPFFSECSLGYFSPAPSLSLPPPPQVS 575
+ E + + E + V +P + L P P P P Q
Sbjct: 1021 ----LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLP--PPPPPPQPPAPIQPQ 1074
Query: 576 SLPPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKS 635
S+PP QP E P L P +D E+P +P + E + ++ + +
Sbjct: 1075 SVPPPIQPEAEKF-----PSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAA 1129
Query: 636 LANKRAFKPEETSSNS------DPPSPPVLNNSHPVP 666
K +PE+ S P S P + +P
Sbjct: 1130 PVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLP 1166
Score = 34.7 bits (78), Expect = 0.96
Identities = 89/453 (19%), Positives = 174/453 (38%), Gaps = 76/453 (16%)
Query: 711 LNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPE-- 768
LN SDD E + K NS +Q SK +++KE D + +
Sbjct: 332 LNFSDDDEQGSNSPKENNS---------------EDQGSKASENNENKKETDEVSNTKSS 376
Query: 769 ----ALPEEKKIEYRLLKEEIANREK---QRLIKSDQLKTSSSSPANSDVEIDGIGRIAM 821
A P K+ Y K N+E+ L +L P + + G
Sbjct: 377 SQIPAQPSVAKVPYG--KGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQA-VPGRPGPFP 433
Query: 822 VTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQAT--E 879
+QV D + K+ R + +S + V++ K++E ++ EQ +A E
Sbjct: 434 SKQQVADEDEIWKQRR----RQQSEISAAVERARKRREEEER------RMEEQRKAACAE 483
Query: 880 KILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFG 939
K LK+L E++ ++++ + ++ + +E R K + ++ +R+ E+++
Sbjct: 484 K--------LKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK-- 533
Query: 940 PNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISP 999
R+ E +EK + ++ E E K +K KE K KE++ +
Sbjct: 534 ------------DRERQQEKEK-ELEKEQEKQREMEKERKQEKEKELERQKEKEKE-LQK 579
Query: 1000 VVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVD-DEILSGSSRERRRSFLESNYFTKPNL 1058
+ E+E E L + ++KL E + + + ++ E + E FT+ +
Sbjct: 580 MKEQEKECEL------EKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDS 633
Query: 1059 KHTDTANKECINKLNKNTVEKPE-LFLGLKIGELQKLYSKADSLKQLILKTTTGITEKVL 1117
++ +++ + +P L + QK +Q +K ++
Sbjct: 634 NRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMK-----QQQWQ 688
Query: 1118 HGQEISVDVDFVTAQSKTMEVKPCPFRPYHSPL 1150
Q+ V V +Q + V P P RP + P+
Sbjct: 689 QQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPM 721
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 60.8 bits (146), Expect = 1e-08
Identities = 84/401 (20%), Positives = 148/401 (36%), Gaps = 53/401 (13%)
Query: 244 KDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKP 303
K ++ +++ Q+ + + Q D K++ KE EEK +V+ + LK
Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKE---EEKPEVENDKEDLLKE 548
Query: 304 LRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLG 363
+ G+ N D + ++ K T +SQG ++ +TR ++ E
Sbjct: 549 KTDDTS--GEDN------DEKEAVASKGRKTANSQGR--RKGRITRSMANEANSEEAITP 598
Query: 364 EDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKV 423
+ EL+ ++L + S +W ++E + K+ + + + ++ S K
Sbjct: 599 QQSAELASMEL------NESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNF 652
Query: 424 STTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERR----KREEEIRKIRDLS 479
K+ + KL+ +KE+ ++++ + A EE +EE+
Sbjct: 653 YFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSG 712
Query: 480 NQEEQYNRFMKL-VGGKRRSRSKSSDP-DLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDS 537
N+EE L G R + S P + S D + S + E A DT
Sbjct: 713 NEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP--------HTEAAKDTGQ 764
Query: 538 ETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPP 597
P +LG P P PP P +P ++P PP
Sbjct: 765 NGPKPP-----------ATLGADGPPPG---PPTPPPEDIPAPTEPTPASEATGAPTPPP 810
Query: 598 LPPLPPLPP------EDPEQPPKPPFADEEEEEEMLLREEL 632
PP P PP E E+ P +E EE++ EEL
Sbjct: 811 APPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEEL 851
Score = 36.2 bits (82), Expect = 0.33
Identities = 30/178 (16%), Positives = 79/178 (44%), Gaps = 20/178 (11%)
Query: 332 DTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLAL--------QSAS 383
+ ++ GL ++E NL +++ ++ D++ + + + L +
Sbjct: 371 EVSEIIDGLSEQE-NLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVM 429
Query: 384 KKWQQKEQQVMKESKEKLTKT----------KTVQQKVKTSTKTHSAKKVSTTAKQALRK 433
W ++E++ +E + K KTV + V T + + +++ R+
Sbjct: 430 NMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRR 489
Query: 434 Q-QTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMK 490
+ +++ ++ QQQ++Q++Q++ R EE++ +++E+E K + E +K
Sbjct: 490 RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLK 547
Score = 31.6 bits (70), Expect = 8.1
Identities = 58/251 (23%), Positives = 88/251 (35%), Gaps = 51/251 (20%)
Query: 432 RKQQTKAWKKLQQQKEQERQKEED---QRKQAEEEERRKREEEIR----KIRDLSNQEEQ 484
++++T A +++ +EQ+ E+ +AEE + + EE K +D E
Sbjct: 827 KEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
Query: 485 YNRFMKLV----GGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETS 540
+K G R + +KSS Q +DS D +E +
Sbjct: 887 AEGALKAEKKEGGSGRATTAKSSGAP-------QDSDSSATC-SADEVDEAEGGDKNRLL 938
Query: 541 SPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQ-VSSLPPLSQPYVEGLCVSLEPLPPLP 599
SP PS + P + SP L L Q +++PP+ E P P P
Sbjct: 939 SPRPSLLTPTGDPRANA---SPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAP 995
Query: 600 PLPPLP----------------PEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFK 643
P PP P P + P PP AD+E E+ + AF
Sbjct: 996 PAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP-ADKEAEKPVFF-----------PAFA 1043
Query: 644 PEETSSNSDPP 654
E DPP
Sbjct: 1044 AEAQKLPGDPP 1054
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 60.5 bits (145), Expect = 2e-08
Identities = 43/160 (26%), Positives = 83/160 (51%), Gaps = 4/160 (2%)
Query: 359 EKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH 418
EKK + E E + + + K+ ++KE++ K+ K+K + + +++ K +
Sbjct: 62 EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
Query: 419 SAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDL 478
++ + ++ RK++ K ++ ++++E+ER K E +RK+ ++EER K+ E RK R
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK- 180
Query: 479 SNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDS 518
+E + R K K R + K D R D+Q TDS
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKD--RKTDRQ-TDS 217
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/236 (19%), Positives = 108/236 (45%), Gaps = 14/236 (5%)
Query: 277 ITKDSSKEVAPEEKTQVKTFQAFEL-KPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTD 335
+ K S A + T+++ + KP Q+ + R K+ ++ K +
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQR-----ESERKKERREREKRKREREKERK 55
Query: 336 SSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMK 395
+G ++K++ R E+K E E++ E + + + KK ++++Q+ +
Sbjct: 56 RERGKKEKKKRKKRERGKE---RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRR 112
Query: 396 ESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEED 455
E K+K + + ++ K +K K+ RK++ + ++ +++++++++K+E+
Sbjct: 113 ERKKKKERKEREREN-----KQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 456 QRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSL 511
+ K+ E + +++E RK R +E + R K K R + +D + R L
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPL 223
Score = 48.5 bits (114), Expect = 6e-05
Identities = 30/142 (21%), Positives = 74/142 (52%), Gaps = 5/142 (3%)
Query: 373 QLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALR 432
+L++++ SK Q+E + KE +E+ K +++ K + K+ K+
Sbjct: 16 ELQMVSCSHISKPCTQRESERKKERRER---EKRKREREKERKRERGKKEKKKRKKRERG 72
Query: 433 KQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLV 492
K++ + K+ ++Q+++ R+KE +RK+ +E+++R+R++ R+ R + ++ R K
Sbjct: 73 KERERKRKEREKQRKERREKE--RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130
Query: 493 GGKRRSRSKSSDPDLRRSLDKQ 514
++R + + R +K+
Sbjct: 131 RERKRKKRRKKKRRKERKREKE 152
Score = 48.5 bits (114), Expect = 6e-05
Identities = 26/131 (19%), Positives = 70/131 (53%)
Query: 384 KKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQ 443
K+ ++KE++ + KEK + K + K + + K+ ++ RK++ + K+ +
Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106
Query: 444 QQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSS 503
+Q+ + +K++ +RK+ E E +++RE + +K R ++E+ + ++R + K
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Query: 504 DPDLRRSLDKQ 514
+ + +R +++
Sbjct: 167 EREKKRERNRK 177
Score = 38.9 bits (89), Expect = 0.051
Identities = 32/162 (19%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Query: 314 KNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQ 373
K R +K K+ K + + + + + KE+ R +KK E E Q
Sbjct: 73 KERERKRKEREKQ---RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 374 LRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRK 433
R + KK ++KE++ KE ++ K K +++ + + + K+ ++ R+
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
Query: 434 QQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKI 475
++ K KK +++K++ ++ + R+ + R RE ++
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 60.5 bits (145), Expect = 2e-08
Identities = 134/614 (21%), Positives = 220/614 (35%), Gaps = 94/614 (15%)
Query: 58 PHSARGGGS-GGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPK----EPFRS 112
P+S R GG G GG+S + S + SR RH H R S + P +
Sbjct: 2 PNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAA 61
Query: 113 HPPSVRMPSSSLSE-SSPRPSFWERSHLALDRFRFRGRPYRGGS----RWSRGRGVGERG 167
+V P + SS +F + LDR R R GS R + R R
Sbjct: 62 SLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR---RENDERRGSDRSDRLHKHRHHQHRR 118
Query: 168 GKPGCRPPLGGGAGSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKN--ENCVEETF 225
+ + S SS+S SSK RS +Y ++ +E+
Sbjct: 119 SRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSK---RSNEETDDYGKAQVAKSSSKESR 175
Query: 226 EDLLLKYK-QIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITK---DS 281
L K K + + EL+ +KD SK +E PK+ D + S + DS
Sbjct: 176 SSKLHKEKTRKERELKSGHKDR-----SKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDS 230
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTL--------PGDKNRLKKVKDGAKPLSLKSDT 333
SK+ + + Q ++L P R + PG +R + V K S +
Sbjct: 231 SKQ--DDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSS 288
Query: 334 TDSSQGLQDKEQNLT-------------------------RRISTSDILSEKKLGEDEEE 368
T S ++++++ RR S+S LS++ L
Sbjct: 289 TRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLP 348
Query: 369 LSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH-SAKKVSTTA 427
+ + S+ ++ S+ + + V+ + +S S KK A
Sbjct: 349 SRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAA 408
Query: 428 KQALRK---QQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
A K +++K +KE + +D ++++ R + E+ +L N
Sbjct: 409 AAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHL 468
Query: 485 YNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAP 544
+ ++S+ L + L Q T I EE+ ++ETS
Sbjct: 469 NTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALK---EEIVTPKETETSEKET 525
Query: 545 SPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPPLPPL 604
P P P+++ PPPP ++ PP P PLPPLPP+P L
Sbjct: 526 PP---------------PLPTIASPPPPLPTTTPPPQTP----------PLPPLPPIPAL 560
Query: 605 PPEDPEQPPKPPFA 618
P + P P +P F+
Sbjct: 561 PQQPPLPPSQPAFS 574
Score = 40.4 bits (93), Expect = 0.017
Identities = 61/209 (29%), Positives = 85/209 (40%), Gaps = 29/209 (13%)
Query: 17 KEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSS 76
++E EL+ G D + R R + S P R R PH + S S S +
Sbjct: 185 RKERELKSGH---KDRSKSHRKRETPKSYKTVDSPKRRSRSPHR-KWSDSSKQDDSPSGA 240
Query: 77 SSSQQQLRNFSRSRHASER-GHLRGPSSYRPKEPFRSHPPSVRMPSSSLSES-SPRPSFW 134
S Q + SRS +S + + P S ++ S P + PS+ S + SP P
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQ---SVSPPYKEPSAYQSSTRSPSPY-- 295
Query: 135 ERSHLALDRFRFRGRPYRGGSRWSRGRGVG-ERGGKPGCRPPLGGG---AGSGFSSSQSW 190
R R S +SR R ER G R P G + S F S +S
Sbjct: 296 -------------SRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSL 342
Query: 191 -REPSPPRKSSKSFGRSPSRKQNYSSKNE 218
R P P RKS KS RSP+ ++ SS ++
Sbjct: 343 SRSPLPSRKSMKSRSRSPAYSRHSSSHSK 371
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 60.5 bits (145), Expect = 2e-08
Identities = 134/614 (21%), Positives = 220/614 (35%), Gaps = 94/614 (15%)
Query: 58 PHSARGGGS-GGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPK----EPFRS 112
P+S R GG G GG+S + S + SR RH H R S + P +
Sbjct: 2 PNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAA 61
Query: 113 HPPSVRMPSSSLSE-SSPRPSFWERSHLALDRFRFRGRPYRGGS----RWSRGRGVGERG 167
+V P + SS +F + LDR R R GS R + R R
Sbjct: 62 SLGTVIKPLVEYDDISSDSDTFSDDMAFKLDR---RENDERRGSDRSDRLHKHRHHQHRR 118
Query: 168 GKPGCRPPLGGGAGSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKN--ENCVEETF 225
+ + S SS+S SSK RS +Y ++ +E+
Sbjct: 119 SRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSK---RSNEETDDYGKAQVAKSSSKESR 175
Query: 226 EDLLLKYK-QIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITK---DS 281
L K K + + EL+ +KD SK +E PK+ D + S + DS
Sbjct: 176 SSKLHKEKTRKERELKSGHKDR-----SKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDS 230
Query: 282 SKEVAPEEKTQVKTFQAFELKPLRQKLTL--------PGDKNRLKKVKDGAKPLSLKSDT 333
SK+ + + Q ++L P R + PG +R + V K S +
Sbjct: 231 SKQ--DDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSS 288
Query: 334 TDSSQGLQDKEQNLT-------------------------RRISTSDILSEKKLGEDEEE 368
T S ++++++ RR S+S LS++ L
Sbjct: 289 TRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLP 348
Query: 369 LSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTH-SAKKVSTTA 427
+ + S+ ++ S+ + + V+ + +S S KK A
Sbjct: 349 SRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAA 408
Query: 428 KQALRK---QQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
A K +++K +KE + +D ++++ R + E+ +L N
Sbjct: 409 AAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHL 468
Query: 485 YNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAP 544
+ ++S+ L + L Q T I EE+ ++ETS
Sbjct: 469 NTEVKNSSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALK---EEIVTPKETETSEKET 525
Query: 545 SPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPPLPPL 604
P P P+++ PPPP ++ PP P PLPPLPP+P L
Sbjct: 526 PP---------------PLPTIASPPPPLPTTTPPPQTP----------PLPPLPPIPAL 560
Query: 605 PPEDPEQPPKPPFA 618
P + P P +P F+
Sbjct: 561 PQQPPLPPSQPAFS 574
Score = 40.4 bits (93), Expect = 0.017
Identities = 61/209 (29%), Positives = 85/209 (40%), Gaps = 29/209 (13%)
Query: 17 KEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSS 76
++E EL+ G D + R R + S P R R PH + S S S +
Sbjct: 185 RKERELKSGH---KDRSKSHRKRETPKSYKTVDSPKRRSRSPHR-KWSDSSKQDDSPSGA 240
Query: 77 SSSQQQLRNFSRSRHASER-GHLRGPSSYRPKEPFRSHPPSVRMPSSSLSES-SPRPSFW 134
S Q + SRS +S + + P S ++ S P + PS+ S + SP P
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQ---SVSPPYKEPSAYQSSTRSPSPY-- 295
Query: 135 ERSHLALDRFRFRGRPYRGGSRWSRGRGVG-ERGGKPGCRPPLGGG---AGSGFSSSQSW 190
R R S +SR R ER G R P G + S F S +S
Sbjct: 296 -------------SRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSL 342
Query: 191 -REPSPPRKSSKSFGRSPSRKQNYSSKNE 218
R P P RKS KS RSP+ ++ SS ++
Sbjct: 343 SRSPLPSRKSMKSRSRSPAYSRHSSSHSK 371
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 60.1 bits (144), Expect = 2e-08
Identities = 59/292 (20%), Positives = 147/292 (50%), Gaps = 21/292 (7%)
Query: 228 LLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAP 287
LLL +Q+Q E + + K E ++S+K + E+ + N +Q + + ++ +E
Sbjct: 256 LLLPQQQLQAEADHLGK-ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-- 312
Query: 288 EEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
EEK Q Q +++ +K+ +K R ++ K ++ + + +KE+ +
Sbjct: 313 EEKIQE---QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKM 365
Query: 348 TRRISTSDILSEK--KLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTK 405
R+ +++ EK K+ EE + E + ++ L+ K +Q++ + +E +++ K +
Sbjct: 366 RRQ---EEMMWEKEEKMRRQEEMMWEKEEKIRELEE--KMHEQEKIREQEEKRQEEEKIR 420
Query: 406 TVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE--- 462
+++ + K ++ ++ +R+Q+ K W++ ++ EQE+ +EE++R++ EE
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 463 -EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDK 513
EE+ +EEI + ++ +++E+ R + ++ + + + +R +K
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 59.3 bits (142), Expect = 4e-08
Identities = 56/281 (19%), Positives = 133/281 (47%), Gaps = 33/281 (11%)
Query: 209 RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFED 268
R++ + E + E E+ + + ++I+ + E ++EK+ +E+ +++ K E+
Sbjct: 381 RQEEMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQEAKMWRQEE 437
Query: 269 QTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLS 328
+ I + K EEK + E K Q+ ++ K+ + +
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE----KIHEQEEIWR 493
Query: 329 LKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQ 388
K + + ++ +E+ + R+ E+K+ E EE++ E + K W+Q
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQ--------EEKIREQEEKIREQE---------EKMWRQ 536
Query: 389 ----KEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQ 444
+EQ+ M +EK+ + Q+K+ K + ++ +R+Q+ K W++ ++
Sbjct: 537 EEKIREQEEMWREEEKMHE----QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 445 QKEQERQKEEDQRKQAEEEER-RKREEEIRKIRDLSNQEEQ 484
+EQE +++E + K ++EE+ R++EE+I++ + ++E+
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Score = 54.3 bits (129), Expect = 1e-06
Identities = 57/300 (19%), Positives = 133/300 (44%), Gaps = 50/300 (16%)
Query: 190 WREPSPPRKSSKSFGRSPS---RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDE 246
WR+ + + + R++ + E + E E + + ++I+ + E ++E
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 247 KLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKT--QVKTFQAFELKPL 304
K+ ++E + E+ K ED+ I + K EEK Q + Q E K
Sbjct: 552 KM---HEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 305 RQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGE 364
+Q+ +K+++ + + + + + +++ +T+ E+K+GE
Sbjct: 609 KQE----------EKIREQEEKIQEQEEKIREQEEKIREQEEMTQE-------QEEKMGE 651
Query: 365 DEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVS 424
EE++ E + ++ + W+Q+E + +E+ K + ++K++
Sbjct: 652 QEEKMCEQEEKM--QEQEETMWRQEE-----KIREQEKKIREQEEKIREQ---------- 694
Query: 425 TTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
++ +++Q+ K W++ ++ EQE + +E + K +EE + E+E+R L QEE+
Sbjct: 695 ---EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE-KMWEQEVR----LRQQEEK 746
Score = 53.9 bits (128), Expect = 2e-06
Identities = 62/344 (18%), Positives = 144/344 (41%), Gaps = 37/344 (10%)
Query: 191 REPSPPRKSSKSFGRSPSRKQNYSS--KNENCVEETFEDLLLKYKQIQLELECINKDEKL 248
RE R+ + R++ + + E + E E + + K++ + E I++ EK+
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466
Query: 249 ALSSK----------EENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKT--QVKTF 296
K EE + E + +++ I K K EEK Q +
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 297 QAFELKPLRQKLTLPGDK---------NRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNL 347
+ E K RQ+ + + + +K+ + K + + ++++E+ +
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 348 TRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQK---EQQVMKESKEKLTKT 404
R+ E+K+ E EE+ E + ++ + ++ ++K +++ ++E +EK+ +
Sbjct: 587 WRQ--------EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 405 KTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEE 464
+ + Q+ + K K +++Q+ W++ ++ +EQE++ E + K E+EE
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEK--MQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 465 RRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLR 508
+ +EE + EQ + + RR K + ++R
Sbjct: 697 MMQEQEE-KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 53.5 bits (127), Expect = 2e-06
Identities = 56/310 (18%), Positives = 146/310 (47%), Gaps = 33/310 (10%)
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEK 247
Q W E ++ R+Q + + + E+ + + +++ E K+EK
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE-----KEEK 364
Query: 248 LALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQK 307
+ +EE + E + + +++ + ++ +++ +EK + + + E + +R++
Sbjct: 365 MR--RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 308 LTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDE- 366
K+ + AK + + + ++++E+ + R+ I ++K+ E+E
Sbjct: 423 E---------KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHEQEKIREEEK 471
Query: 367 -EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTV----QQKVKTSTKTHSAK 421
+E E+ + + + W+QKE+ M E +EK+ K + ++K++ + +
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEK--MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 422 KVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAE------EEERRKREEEI-RK 474
+ ++ ++Q + W++ ++ EQE+ EE++R++ E EE+ R++EE++ R+
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 475 IRDLSNQEEQ 484
+ QEE+
Sbjct: 590 EEKIREQEEK 599
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/297 (16%), Positives = 139/297 (46%), Gaps = 34/297 (11%)
Query: 198 KSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENV 257
+ ++ + R +++ + E ++E E + + ++I+ + E I + E+ +E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 258 QEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFE----LKPLRQKLTLPGD 313
+++ K E+ + + EEK + + +E ++ L +K+ +
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH---E 402
Query: 314 KNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQ 373
+ ++++ ++ + + + + Q++E + R+ E+K+ E EE++ E +
Sbjct: 403 QEKIREQEEKRQ----EEEKIREQEKRQEQEAKMWRQ--------EEKIREQEEKIREQE 450
Query: 374 LRLLALQSASKKWQQK----EQQVMKESKEKLTKTKTVQQ--KVKTSTKTHSAKKVSTTA 427
K W+Q+ EQ+ ++E +++ + + +Q K+ + K+
Sbjct: 451 ---------KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
Query: 428 KQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
++ +RKQ+ K W++ ++ +EQE + E + K +EE+ + +EE+ + + +++E+
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Score = 50.8 bits (120), Expect = 1e-05
Identities = 56/305 (18%), Positives = 142/305 (46%), Gaps = 36/305 (11%)
Query: 190 WREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKL- 248
WR+ + K ++Q + E + E E K K + E + ++EK+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 249 ----ALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPL 304
+ +EE ++E + + +++ + + ++ K E+ + + Q E K
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Query: 305 RQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGE 364
RQ+ + + ++ + ++ + + + Q++E+ + ++ E+K+ E
Sbjct: 574 RQEEKIREQEEKVWRQEEKIR---------EQEEKRQEQEEKMWKQ--------EEKIRE 616
Query: 365 DEEELSELQLRLLALQSASKKWQ---QKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAK 421
EE++ E + ++ + ++ + Q++++ M E +EK+ + + Q+ + T +
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE-QEETMWRQEE 675
Query: 422 KVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE--EERRKREEEIRKIRDLS 479
K+ K+ +R+Q+ +K+++Q+E +++EE +Q E+ E+ K +E+ K+R
Sbjct: 676 KIREQEKK-IREQE----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR--- 727
Query: 480 NQEEQ 484
QEE+
Sbjct: 728 RQEEK 732
Score = 47.0 bits (110), Expect = 2e-04
Identities = 52/317 (16%), Positives = 147/317 (46%), Gaps = 28/317 (8%)
Query: 205 RSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTL 264
R K + K E+ E+ ++ ++ + E E ++ + +EE ++E K +
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 265 NFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGA 324
+++ + I ++ ++ E Q + E + RQK + + +++K ++
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE-EIWRQKEKMHEQEEKIRKQEE-- 510
Query: 325 KPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASK 384
K + + + ++++E+ + R+ E+K+ E EE E + + K
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQ--------EEKIREQEEMWREEE----KMHEQEK 558
Query: 385 KWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWK---K 441
W+++++Q +E K + K +Q+ K + ++ ++ ++Q+ K WK K
Sbjct: 559 IWEEEKRQE-QEDKMWRQEEKIREQEEKVWRQEEKIRE----QEEKRQEQEEKMWKQEEK 613
Query: 442 LQQQKE-----QERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKR 496
+++Q+E +E+ +E++++ + +EE +++EE++ + + ++E+ + + ++
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 497 RSRSKSSDPDLRRSLDK 513
+ + + +R +K
Sbjct: 674 EEKIREQEKKIREQEEK 690
Score = 40.0 bits (92), Expect = 0.023
Identities = 54/313 (17%), Positives = 135/313 (43%), Gaps = 9/313 (2%)
Query: 696 RTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPP 755
R +SL +++ + + + E + S ++ +KE +R E+A
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 756 KSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDG 815
+ + E D L E K++ ++ + E+ NR Q+ + + ++ +
Sbjct: 262 QLQAEADHLGK-ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQ 319
Query: 816 IGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQL 875
+I +++ + E K+++ ++ + E ++ + +K+E +R E + + E++
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379
Query: 876 QATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGK--RKL 933
+ E+++ +++L+E++H ++ I++ + EE R + ++ K R+
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEK---IREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 934 EQDRFGPNKMMRLDSSPVSSPRK-HSAELIAMEKRRLQKLE-YEYALKIQKLKEARALKA 991
E+ R K+ + K H E I E++R ++ E + KI + +E K
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 992 KEQQNISPVVEEE 1004
K + + ++E
Sbjct: 497 KMHEQEEKIRKQE 509
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 60.1 bits (144), Expect = 2e-08
Identities = 42/171 (24%), Positives = 89/171 (52%), Gaps = 19/171 (11%)
Query: 335 DSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVM 394
+ + +Q++E+ + + E+K+ E EE++ E Q RL + K W+Q E+ +
Sbjct: 44 EQEEKMQEQEEKMWEQ--------EEKMWEQEEKMWEQQ-RLP--EQKEKMWEQDER--L 90
Query: 395 KESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEE 454
+E +E++ + K QQ K K + ++ ++ +++Q+ W++ ++ +EQE + E
Sbjct: 91 REKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE 150
Query: 455 DQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDP 505
+ K E+EE+ + +EE + QEE+ R ++ GG+ S +P
Sbjct: 151 QEEKMREQEEKMREQEE-----KMQGQEEKM-RDVEPAGGEAGEGSPQDNP 195
Score = 47.0 bits (110), Expect = 2e-04
Identities = 35/156 (22%), Positives = 73/156 (46%), Gaps = 8/156 (5%)
Query: 359 EKKLGEDEEELSELQLRLLALQSA-----SKKWQQKEQQVMKESK--EKLTKTKTVQQKV 411
EKK+ E+EE + E + ++ + K W+Q+E+ +E K E+ K ++K+
Sbjct: 11 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 70
Query: 412 KTSTKTHSAKKVSTTAKQALR-KQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREE 470
+ K+ + LR K++ +K+ QQ E+ R+K++ Q ++ +E+E + +E+
Sbjct: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 471 EIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPD 506
E +EQ + + R K + +
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
Score = 46.2 bits (108), Expect = 3e-04
Identities = 31/142 (21%), Positives = 77/142 (54%), Gaps = 12/142 (8%)
Query: 343 KEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT 402
+E+ + R E+K+ E EE++ E + ++ + K W+Q+E+ M E +EK+
Sbjct: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ--EQEEKMWEQEEK--MWEQEEKMW 71
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
+ + + ++ K ++ ++ R ++ K W+++++ +E+++ +EE K E+
Sbjct: 72 EQQRLPEQ-----KEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE---KMQEQ 123
Query: 463 EERRKREEEIRKIRDLSNQEEQ 484
EE+ + +EE+ ++ QE++
Sbjct: 124 EEKMQEQEEMMWEQEEKMQEQE 145
Score = 33.5 bits (75), Expect = 2.1
Identities = 11/54 (20%), Positives = 37/54 (68%)
Query: 431 LRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQ 484
+R+++ ++ + ++E+E +E++++ Q +EE+ R++EE++ + + ++E+
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
Score = 32.7 bits (73), Expect = 3.6
Identities = 14/61 (22%), Positives = 33/61 (54%)
Query: 411 VKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREE 470
++ + +K ++ +R+Q+ K ++ ++ +EQE + E + K E+EE+ +E
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 471 E 471
E
Sbjct: 61 E 61
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 59.7 bits (143), Expect = 3e-08
Identities = 88/401 (21%), Positives = 148/401 (36%), Gaps = 67/401 (16%)
Query: 378 ALQSASKKWQQKE-QQVMKESKEKLTKTKTVQQKVKTSTK------------THSAKKVS 424
AL+ S K ++KE ++ + S+EK + T ++ + + T K+
Sbjct: 887 ALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDE 946
Query: 425 TTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEI------RKIRDL 478
K + +++ A ++ QE E+D+ E+EE REE + ++ D
Sbjct: 947 ERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDG 1006
Query: 479 SNQEEQYNRFMKLVGGKRRSRSKSSDPD-LRRSLDKQPTDSGGGIYQYDNYEEVAMDTDS 537
++E + L +SD + S + S + E + + +
Sbjct: 1007 EDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEE 1066
Query: 538 ETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPP 597
E PA P P E + +PAP + +P P +V+ P P E P P
Sbjct: 1067 EEERPAALPSASPPPREVPVP--TPAP-VEVPVPERVAGSPVTPLPEQEA-----SPARP 1118
Query: 598 LPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPP 657
P PP P +PP+PP A +P+E S+ P PP
Sbjct: 1119 AGPTEESPPSAPLRPPEPPAGPPAP------------------APRPDERPSSPIPLLPP 1160
Query: 658 VLNNSHPVPRSNLSIVSI-----NTVSQPRIQNPKFHRGPR-LPRTVISLP-KHKSVVVT 710
V S + +V T Q + P + PR + RT+ +LP H S+V +
Sbjct: 1161 PKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKS 1220
Query: 711 LNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKP 751
+ E S+ S GG R T E+ ++P
Sbjct: 1221 WPE--------EVSRGGRSRAGG------RGRLTEEEEAEP 1247
Score = 48.5 bits (114), Expect = 6e-05
Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 16/87 (18%)
Query: 530 EVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLC 589
E++ D + PAP+P Q P P P PPPP ++SLP P+
Sbjct: 584 EISDDDRGGSPPPAPTPPQQP----------PPPPPPPPPPPPYLASLPLGYPPHQPAYL 633
Query: 590 VSLEPLPPLPPLPPLPPEDPEQPPKPP 616
LPP P PP PPE P PP PP
Sbjct: 634 -----LPPRPDGPP-PPEYPPPPPPPP 654
Score = 39.7 bits (91), Expect = 0.030
Identities = 60/296 (20%), Positives = 110/296 (37%), Gaps = 34/296 (11%)
Query: 8 APASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSG 67
A +SS S + + D + + S+S+++ + SA
Sbjct: 286 AYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLS 345
Query: 68 GGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMPSSSLSES 127
SSSSSSSSQ + + + + + +SY P+ R PP ++ +E
Sbjct: 346 SSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENT-AER 404
Query: 128 SPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGAGSGFSSS 187
P PS+ S+L + R + YR + + P P GGG G G S
Sbjct: 405 FP-PSY--TSYLPPEPSRPTDQDYRPPASEA----------PPPEPPEPGGGGGGGGPSP 451
Query: 188 QSWREPSPPRKSSKSFGRSPSRKQN-------YSSKNENCVEETFEDLLLKYKQIQLELE 240
+ + PR +S + SP+ + S ++ +E ++ K+ + + E
Sbjct: 452 EREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTE 511
Query: 241 CINKDEKLALSSKEENVQ-----------EDPKTLNFED--QTSTDNVSITKDSSK 283
++ + L +++ + P NFED T + T++S K
Sbjct: 512 EEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPK 567
Score = 32.7 bits (73), Expect = 3.6
Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 6/113 (5%)
Query: 17 KEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSS 76
K+E E+ DGE + D++S+ + S S+ S SSSSS
Sbjct: 998 KKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSS 1057
Query: 77 SSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMPSSSLSESSP 129
S S S ER +S P+E P V +P SP
Sbjct: 1058 SESS------SEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSP 1104
Score = 32.0 bits (71), Expect = 6.2
Identities = 39/156 (25%), Positives = 49/156 (31%), Gaps = 11/156 (7%)
Query: 51 PYPRRRPPHSARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPF 110
P PP GG GGGGG S + R S +R S P + PF
Sbjct: 428 PASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSP-----APETTNESVPF 482
Query: 111 RSHPPSVRMPSSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKP 170
H L E + SF LA D G V G
Sbjct: 483 AQHSSLDSRIEMLLKEQRSKFSF-----LASDTEEEEENSSMVLGARDTGSEVPSGSGHG 537
Query: 171 GCRPPLGGGAGSGFSSSQSWREPSPPRKSSKSFGRS 206
C PP + + S EP R+S K+ G++
Sbjct: 538 PCTPPPAPANFEDVAPTGS-GEPGATRESPKANGQN 572
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 59.7 bits (143), Expect = 3e-08
Identities = 89/418 (21%), Positives = 161/418 (38%), Gaps = 43/418 (10%)
Query: 204 GRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKT 263
G+S N+ + N + ++ LKY + KD K + ED K
Sbjct: 252 GQSDDESINFDAWLRNYSQNNSKNYSLKYTKYT------KKDTKKNAKKSSDAESEDSKD 305
Query: 264 LNFEDQTSTDNVSITKDSSKEVAPE-EKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKD 322
+ + NV D K+V + E T ++ + + + +K DK +LKK D
Sbjct: 306 AKKDSKKVKKNVK-KDDKKKDVKKDTESTDAESGDSKDERKDTKK-----DKKKLKK-DD 358
Query: 323 GAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSA 382
K ++TD+ G +N +R + + +KK ++ ++ +
Sbjct: 359 KKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKK-----KDAKKITFSTDSESEL 413
Query: 383 SKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKL 442
K QK+++ K+ K+ T K + + ST S K + + K+ K KK
Sbjct: 414 ESKESQKDEK--KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKD 471
Query: 443 QQQKEQERQKEEDQ----------RKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLV 492
++K+ ++ E + +K ++E++ K++ + +D + + +++ K
Sbjct: 472 DKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSK-T 530
Query: 493 GGKRRSRSKSSDPDLRRSL----DKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAPSPVQ 548
G K ++ K SD + SL K+ D G E + SS + +
Sbjct: 531 GFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNE 590
Query: 549 PPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLC-VSLEPLPPLPPLPPLP 605
+ S G P S PP + P L P V LC + P PP P PLP
Sbjct: 591 KG--EKASTGRVPP----SREKPPLPACEPSLPSPKVRRLCWCKMPPPPPKPRYAPLP 642
Score = 53.1 bits (126), Expect = 3e-06
Identities = 75/371 (20%), Positives = 149/371 (40%), Gaps = 46/371 (12%)
Query: 187 SQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDE 246
S+S E +P ++SK+ ++ S+K SKN F K+ + N
Sbjct: 175 SKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPI 234
Query: 247 KLALSSKEENV-------QEDPKTLNFE------DQTSTDNVSI--TKDSSKEVAPEEKT 291
S NV Q D +++NF+ Q ++ N S+ TK + K+ K
Sbjct: 235 SEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAK- 293
Query: 292 QVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDT--TDSSQGLQDKEQNLTR 349
++ + + K K K VK K +K DT TD+ G E+ T+
Sbjct: 294 -----KSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTK 348
Query: 350 RISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQ 409
+ +KKL +D+++ +KK+ + ++K+ ++ +++
Sbjct: 349 K-------DKKKLKKDDKKKD------------TKKYPESTDTESGDAKDARNDSRNLKK 389
Query: 410 KVKTSTKTHSAKKV--STTAKQALR-KQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERR 466
K K AKK+ ST ++ L K+ K KK ++ + + +K +++ + +
Sbjct: 390 ASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449
Query: 467 KREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYD 526
+ + + +D ++ + K K+ + S + DL DK+ + G + D
Sbjct: 450 PKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKG-SKKD 508
Query: 527 NYEEVAMDTDS 537
++ DT+S
Sbjct: 509 IKKDARKDTES 519
Score = 40.0 bits (92), Expect = 0.023
Identities = 63/330 (19%), Positives = 130/330 (39%), Gaps = 23/330 (6%)
Query: 705 KSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPL 764
K V + D + + ++ST++ G + K+ ++ ++ K ++K +
Sbjct: 311 KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPEST 370
Query: 765 RTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANS------------DVE 812
T ++ + + R LK+ N +K++ K T S S S D +
Sbjct: 371 DTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSK 430
Query: 813 IDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLT 872
D + ++ TDA+S+ K KDE K +++ KKK++ +NAE+ +
Sbjct: 431 TDNKKSVKN-DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESD 489
Query: 873 EQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRK 932
+L+ +K + K +++ + + + + K G K + +
Sbjct: 490 LELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTG-----FKTSTKIKGSDTE 544
Query: 933 LEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAK 992
E+ + P ++D S +S L + R+ + + K +K R ++
Sbjct: 545 SEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSR 604
Query: 993 EQQNISPVVEEEPEFSLPQPSLHDLTQDKL 1022
E+ P+ EP SLP P + L K+
Sbjct: 605 EK---PPLPACEP--SLPSPKVRRLCWCKM 629
Score = 32.3 bits (72), Expect = 4.7
Identities = 42/209 (20%), Positives = 88/209 (42%), Gaps = 20/209 (9%)
Query: 930 KRKLEQDRFGPNKMMRLDSSPVSS-PRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARA 988
KRKLE+ + +K +R + P ++A R + Y K LK+A
Sbjct: 63 KRKLEEGQKPAHKWIRHSFRKILQWPPIYTAA------REQTPFRHLYTSKTH-LKKAEY 115
Query: 989 LKAKEQQNISPVVEEEPEFS---LPQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRR 1045
K+K+++ +P+ ++ + P + ++K +N+ D L S +
Sbjct: 116 KKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTK---RQNEADKTPLKSSHENEQS 172
Query: 1046 SFLESNYFTKPNLKHTDTANKECI---NKLNKNTVEKPELFLGLKIG---ELQKLYSKAD 1099
+S+ T P +++ T +K C K +KN+ + FL K +L++ + D
Sbjct: 173 KKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSND 232
Query: 1100 SLKQLILKTTTGITEKVLHGQEISVDVDF 1128
+ ++ + + + +L GQ ++F
Sbjct: 233 PISEICSENSLNVDFLMLVGQSDDESINF 261
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 59.3 bits (142), Expect = 4e-08
Identities = 73/280 (26%), Positives = 136/280 (48%), Gaps = 45/280 (16%)
Query: 233 KQIQLELECINKDEKLALSSKEEN----VQEDPKTLNFEDQTSTDNVSITKDSSKEVAPE 288
+Q QLE E + E L +KE+ ++ KTL FE + D
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND--------------- 487
Query: 289 EKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLK-SDTTDSSQGLQDKEQNL 347
+K Q++ +L+ +R +LT + ++++ K L+ ++ T Q LQ+ +Q L
Sbjct: 488 KKHQLEG----KLQDIRCRLT-----TQRQEIESTNKSRELRIAEITHLQQQLQESQQML 538
Query: 348 TRRISTSDILSE--KKLGEDE---EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT 402
R I IL++ K++ ++ + L L+ L A + A + + + +V KE++ KL
Sbjct: 539 GRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQ 598
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
+ ++K + H+ KQ L+KQ++ ++L+Q KEQER K + KQ EE
Sbjct: 599 EIDIFNNQLKELREIHN--------KQQLQKQKSMEAERLKQ-KEQER-KIIELEKQKEE 648
Query: 463 EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKS 502
+RR +E + + + + QE+++ R KL ++ R +S
Sbjct: 649 AQRRAQERDKQWLEHVQ-QEDEHQRPRKLHEEEKLKREES 687
Score = 54.7 bits (130), Expect = 9e-07
Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 33/186 (17%)
Query: 318 KKVKDGAKPLSLKSDTTDS----SQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQ 373
++V+ G+ + S + D L+D++Q L +++ + +KK E EL+
Sbjct: 309 RRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVT--FEDKKRENFERGNLELE 366
Query: 374 LRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRK 433
R AL +K Q++ Q+ + +E+ + + Q+ RK
Sbjct: 367 KRRQALLEQQRKEQERLAQLERAEQERKERERQEQE----------------------RK 404
Query: 434 QQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVG 493
+Q + K+L++Q+E ERQ+EE++RK+ E E KRE E ++ E + NR +L+
Sbjct: 405 RQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQR-----QLEWERNRRQELLN 459
Query: 494 GKRRSR 499
+ + +
Sbjct: 460 QRNKEQ 465
Score = 46.6 bits (109), Expect = 2e-04
Identities = 64/306 (20%), Positives = 132/306 (43%), Gaps = 35/306 (11%)
Query: 209 RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFED 268
+++N+ N +E+ + LL + ++ Q L + + E+ +E QE + L E
Sbjct: 354 KRENFERGNLE-LEKRRQALLEQQRKEQERLAQLERAEQ-ERKERERQEQERKRQLELEK 411
Query: 269 QTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLK-------KVK 321
Q ++ ++ E + +++ +A + + RQ+ L ++NR + K +
Sbjct: 412 QLEKQ-----RELERQREEERRKEIERREAAKRELERQR-QLEWERNRRQELLNQRNKEQ 465
Query: 322 DGAKPLSLKSDTTDSS-QGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQ 380
+ L K T + + L DK+ L ++ + E E +LR+ +
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 381 SASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHS------AKKVSTTAKQALRKQ 434
++ Q+ +Q + + EK ++Q + S S A + A+Q LR Q
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 435 QTKAWK----KLQQ---------QKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQ 481
+ K KLQ+ + + K++ Q++++ E ER K++E+ RKI +L Q
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQ 645
Query: 482 EEQYNR 487
+E+ R
Sbjct: 646 KEEAQR 651
Score = 42.7 bits (99), Expect = 0.004
Identities = 62/308 (20%), Positives = 124/308 (40%), Gaps = 39/308 (12%)
Query: 827 TDAESKLKKHRILLMKDESVLKNL-VQQEAKKKESVRNAEAKITK-----LTEQLQATEK 880
T + +L + +L + + + K L V E KK+E+ ++ K L +Q + E+
Sbjct: 323 TSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER 382
Query: 881 ILNVNRMFLKKL------QEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLE 934
+ + R ++ QE+ +++ ++K L+ E R K + +E KR+LE
Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442
Query: 935 QDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYAL----------KIQKLK 984
+ R + R + + R E I + K + + LE+E K+Q ++
Sbjct: 443 RQR--QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIR 500
Query: 985 --------EARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVDDEIL 1036
E + + I+ + + + Q L L +K L+ + V L
Sbjct: 501 CRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSL 560
Query: 1037 SGSSRERRRSFLESNYFTKPNLK-HTDTANKECINKLNKNTVEKPELFLGLKIGELQKLY 1095
S + LE+ + +L+ D KE +KL + + +L EL++++
Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQL------KELREIH 614
Query: 1096 SKADSLKQ 1103
+K KQ
Sbjct: 615 NKQQLQKQ 622
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 59.3 bits (142), Expect = 4e-08
Identities = 73/280 (26%), Positives = 136/280 (48%), Gaps = 45/280 (16%)
Query: 233 KQIQLELECINKDEKLALSSKEEN----VQEDPKTLNFEDQTSTDNVSITKDSSKEVAPE 288
+Q QLE E + E L +KE+ ++ KTL FE + D
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND--------------- 487
Query: 289 EKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLK-SDTTDSSQGLQDKEQNL 347
+K Q++ +L+ +R +LT + ++++ K L+ ++ T Q LQ+ +Q L
Sbjct: 488 KKHQLEG----KLQDIRCRLT-----TQRQEIESTNKSRELRIAEITHLQQQLQESQQML 538
Query: 348 TRRISTSDILSE--KKLGEDE---EELSELQLRLLALQSASKKWQQKEQQVMKESKEKLT 402
R I IL++ K++ ++ + L L+ L A + A + + + +V KE++ KL
Sbjct: 539 GRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQ 598
Query: 403 KTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEE 462
+ ++K + H+ KQ L+KQ++ ++L+Q KEQER K + KQ EE
Sbjct: 599 EIDIFNNQLKELREIHN--------KQQLQKQKSMEAERLKQ-KEQER-KIIELEKQKEE 648
Query: 463 EERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKS 502
+RR +E + + + + QE+++ R KL ++ R +S
Sbjct: 649 AQRRAQERDKQWLEHVQ-QEDEHQRPRKLHEEEKLKREES 687
Score = 54.7 bits (130), Expect = 9e-07
Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 33/186 (17%)
Query: 318 KKVKDGAKPLSLKSDTTDS----SQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQ 373
++V+ G+ + S + D L+D++Q L +++ + +KK E EL+
Sbjct: 309 RRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVT--FEDKKRENFERGNLELE 366
Query: 374 LRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRK 433
R AL +K Q++ Q+ + +E+ + + Q+ RK
Sbjct: 367 KRRQALLEQQRKEQERLAQLERAEQERKERERQEQE----------------------RK 404
Query: 434 QQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVG 493
+Q + K+L++Q+E ERQ+EE++RK+ E E KRE E ++ E + NR +L+
Sbjct: 405 RQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQR-----QLEWERNRRQELLN 459
Query: 494 GKRRSR 499
+ + +
Sbjct: 460 QRNKEQ 465
Score = 46.6 bits (109), Expect = 2e-04
Identities = 64/306 (20%), Positives = 132/306 (43%), Gaps = 35/306 (11%)
Query: 209 RKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFED 268
+++N+ N +E+ + LL + ++ Q L + + E+ +E QE + L E
Sbjct: 354 KRENFERGNLE-LEKRRQALLEQQRKEQERLAQLERAEQ-ERKERERQEQERKRQLELEK 411
Query: 269 QTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLK-------KVK 321
Q ++ ++ E + +++ +A + + RQ+ L ++NR + K +
Sbjct: 412 QLEKQ-----RELERQREEERRKEIERREAAKRELERQR-QLEWERNRRQELLNQRNKEQ 465
Query: 322 DGAKPLSLKSDTTDSS-QGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQ 380
+ L K T + + L DK+ L ++ + E E +LR+ +
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 381 SASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHS------AKKVSTTAKQALRKQ 434
++ Q+ +Q + + EK ++Q + S S A + A+Q LR Q
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 435 QTKAWK----KLQQ---------QKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQ 481
+ K KLQ+ + + K++ Q++++ E ER K++E+ RKI +L Q
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQ 645
Query: 482 EEQYNR 487
+E+ R
Sbjct: 646 KEEAQR 651
Score = 42.7 bits (99), Expect = 0.004
Identities = 62/308 (20%), Positives = 124/308 (40%), Gaps = 39/308 (12%)
Query: 827 TDAESKLKKHRILLMKDESVLKNL-VQQEAKKKESVRNAEAKITK-----LTEQLQATEK 880
T + +L + +L + + + K L V E KK+E+ ++ K L +Q + E+
Sbjct: 323 TSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER 382
Query: 881 ILNVNRMFLKKL------QEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLE 934
+ + R ++ QE+ +++ ++K L+ E R K + +E KR+LE
Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442
Query: 935 QDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYAL----------KIQKLK 984
+ R + R + + R E I + K + + LE+E K+Q ++
Sbjct: 443 RQR--QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIR 500
Query: 985 --------EARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVDDEIL 1036
E + + I+ + + + Q L L +K L+ + V L
Sbjct: 501 CRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSL 560
Query: 1037 SGSSRERRRSFLESNYFTKPNLK-HTDTANKECINKLNKNTVEKPELFLGLKIGELQKLY 1095
S + LE+ + +L+ D KE +KL + + +L EL++++
Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQL------KELREIH 614
Query: 1096 SKADSLKQ 1103
+K KQ
Sbjct: 615 NKQQLQKQ 622
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 59.3 bits (142), Expect = 4e-08
Identities = 74/343 (21%), Positives = 144/343 (41%), Gaps = 57/343 (16%)
Query: 206 SPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLN 265
S R Q ++N+N V+ LL+ +Q +L++E A+ EEN + L
Sbjct: 36 SQIRNQMVQNENDNRVQRKQFLRLLQNEQFELDME-------EAIQKAEENKRLKELQLK 88
Query: 266 FEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPG-DKNRLKKV--KD 322
E++ + + + +S K+ E+ Q + EL+ L +KL +K R ++ KD
Sbjct: 89 QEEKLAMELAKLKHESLKD---EKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEKD 145
Query: 323 GAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRL---LAL 379
K +K D + +++ ++ I+ E+ ED+ ++ Q L L
Sbjct: 146 AIKYEQMKRDAEIAKTMMEEHKR----------IIKEENAAEDKRNKAKAQYYLDLEKQL 195
Query: 380 QSASKKWQQKEQQVMK------------------ESKEKLTKTKTVQQKVKTSTKTHSAK 421
+ KK Q+ +Q++K E ++KL K +++ ++ K +
Sbjct: 196 EEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALW 255
Query: 422 KVSTTAKQALRKQQTKAWKKLQQQKEQER----QKEEDQRKQAEEEERRKREEEIRKIRD 477
+ + ++ + +QQQ+E++R Q+ E++R Q + +K EE +R+ D
Sbjct: 256 RKKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQRED 315
Query: 478 LSN------QEEQ---YNRFMKLVGGKRRSRSKSSDPDLRRSL 511
L QEEQ Y +K K+ + K D +
Sbjct: 316 LEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQM 358
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 58.9 bits (141), Expect = 5e-08
Identities = 123/553 (22%), Positives = 210/553 (37%), Gaps = 85/553 (15%)
Query: 329 LKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQ 388
+ + +SS L++ + + IS S ++L +D E LSE + +
Sbjct: 663 ISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSE------DTDYEEDEVTK 716
Query: 389 KEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQ 448
K + V K++ +K +K + + K + K S K+ K + +
Sbjct: 717 KRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSS 776
Query: 449 ERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLR 508
+ +EE + K ++ EE+ + +R Y+ F + V KR +SD L+
Sbjct: 777 DEDEEETKAKMTPTKKYNGLEEKRKSLRTTG----FYSGFSE-VAEKRIKLLNNSDERLQ 831
Query: 509 RSLDKQPTD---SGGGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYF----- 560
S K D S G + +E+ D+D+E ++ P P +E SL
Sbjct: 832 NSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEES 891
Query: 561 -SPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLE-PLPPLPPLPPLPPEDPEQPPKPPFA 618
SP+ L PPP V S P+ + VE E P + PP PE P
Sbjct: 892 CSPSVELEKPPPVNVDS-KPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSVTVT 950
Query: 619 D-EEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPS-----PPVLNNSHPVPRSNLSI 672
+ ++ + + E L + R+ K ET S + S + + + P +
Sbjct: 951 EGSRQQSSVTVSEPLAPNQEEVRSIK-SETDSTIEVDSVAGELQDLQSEGNSSPAGFDAS 1009
Query: 673 VSINTVSQPRIQNP-KFHRGPRLPR--------TVISLPKHKSVVVT-------LNDSDD 716
VS ++ +QP ++P K G + + + HK+ VV N SD
Sbjct: 1010 VSSSSSNQPEPEHPEKACTGQKRVKDAQGGGSSSKKQKRSHKATVVNNKKKGKGTNSSDS 1069
Query: 717 SE-SDGEA---SKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALP- 771
E S GE+ S+ SV G++S + A S K +K+ D LP
Sbjct: 1070 EELSAGESITKSQPVKSVSTGMKS--HSTKSPARTQSPGKCGKNGDKDPDLKEPSNRLPK 1127
Query: 772 ---------------------------EEKKIEYRLLKEEIA--NREKQRLIKSDQ---- 798
+E + Y LK E+A +R ++RL K ++
Sbjct: 1128 VYKWSFQMSDLENMTSAERITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAA 1187
Query: 799 LKTSSSSPANSDV 811
+SSSSP++S +
Sbjct: 1188 TSSSSSSPSSSSI 1200
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 58.5 bits (140), Expect = 6e-08
Identities = 58/268 (21%), Positives = 120/268 (44%), Gaps = 16/268 (5%)
Query: 208 SRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFE 267
S + + + N E EDL + + L+ E IN D + L ++ E +Q + K L +
Sbjct: 1030 SEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNE-DLLARIETLQSNAKLLEVQ 1088
Query: 268 D-QTSTDNVSITKDSSKEVAPEEK------TQVKTFQAFELKPLRQKLTLPGDKNRLKKV 320
+ + K+ E +E+ T V + +++ ++K L L+ V
Sbjct: 1089 ILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELV 1148
Query: 321 KDGAKPLSLKS-DTTDSSQGLQDKEQNLTRRIST-SDILSEKKLGEDEEELSELQLRLLA 378
K A+ +L + + D + +++ Q LT + + D+ E K+ + ++E LQ + +
Sbjct: 1149 KKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQET--LQEEITS 1206
Query: 379 LQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKA 438
LQS+ +++++K ++ K+ L KTK K + H + S + +QQ +
Sbjct: 1207 LQSSVQQYEEKNTKI----KQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEV 1262
Query: 439 WKKLQQQKEQERQKEEDQRKQAEEEERR 466
+K + E+ K + K + E+ +R
Sbjct: 1263 YKIQLAEITSEKHKIHEHLKTSAEQHQR 1290
Score = 55.1 bits (131), Expect = 7e-07
Identities = 69/272 (25%), Positives = 128/272 (47%), Gaps = 41/272 (15%)
Query: 223 ETFEDLLLKYKQ----IQLELECINKDEKLALSS---KEENVQEDPKTLNFEDQTSTDNV 275
E + LL Y+Q ++ ELE I + EK AL S + +N E + N + V
Sbjct: 827 EELKSLLRDYEQEKVLLRKELEEI-QSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEV 885
Query: 276 SITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDG-AKPLSLKSDTT 334
S T S+ +EK +K + LKPL ++ L + L +KD AK S+K+D
Sbjct: 886 SQTCSKSEIHNEKEKCFIKEHE--NLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPL 943
Query: 335 DSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVM 394
S + L++K +NL EK+ E EE++++++L V
Sbjct: 944 SSVKELEEKIENL-----------EKECKEKEEKINKIKL------------------VA 974
Query: 395 KESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEE 454
++K++L ++ Q VK ++ ++K +A Q +++K L + E++ ++ +
Sbjct: 975 VKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLD 1034
Query: 455 DQRKQAEEEERRKREEEIRKIRDLSNQEEQYN 486
++++A E R E+ R++R+ + Q E N
Sbjct: 1035 VEKERANNFEHR-IEDLTRQLRNSTLQCETIN 1065
Score = 42.7 bits (99), Expect = 0.004
Identities = 88/426 (20%), Positives = 170/426 (39%), Gaps = 66/426 (15%)
Query: 622 EEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSIVSINTVSQP 681
E+E++LLR+EL + + K A + + + + N + + +S T S+
Sbjct: 837 EQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVS----QTCSKS 892
Query: 682 RIQNP------KFHRGPRLPRTVISLPKHKSVVVTLNDS--DDSESDGEASKSTNSVFGG 733
I N K H + L ++ ++ L DS + S +
Sbjct: 893 EIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEK 952
Query: 734 LESMIKEARRTAEQASKPK-VPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQR 792
+E++ KE + E+ +K K V K++KE D R E + +KEE+ + ++
Sbjct: 953 IENLEKECKEKEEKINKIKLVAVKAKKELDSSRK----------ETQTVKEELESLRSEK 1002
Query: 793 LIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQ 852
DQL S + D + ++ LL++ E + L
Sbjct: 1003 ----DQLSAS-----------------------MRDLIQGAESYKNLLLEYEKQSEQL-- 1033
Query: 853 QEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLK 912
+KE N E +I LT QL+ + + L +I +Q + + L
Sbjct: 1034 --DVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQIL- 1090
Query: 913 YGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKL 972
E+ RAKA+ KE+ KL+++ + ++ ++ V+ + +L EK++LQK
Sbjct: 1091 ---EVQRAKAMVDKELEAEKLQKE-----QKIKEHATTVNELEELQVQL-QKEKKQLQKT 1141
Query: 973 EYEYALKIQKLKEARALKAKEQQNISPVVEE-EPEFSLPQPSLHDLTQDKLTLDTEENDV 1031
E L ++K + L E + +++E + + + DL Q+ ++ +
Sbjct: 1142 MQELEL-VKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1200
Query: 1032 DDEILS 1037
+EI S
Sbjct: 1201 QEEITS 1206
Score = 39.7 bits (91), Expect = 0.030
Identities = 110/526 (20%), Positives = 194/526 (36%), Gaps = 126/526 (23%)
Query: 675 INTVSQPRIQNPKFHRG-PRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGG 733
IN + + FH+ R R ++ L K + N E + N + GG
Sbjct: 600 INKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNS--------ELEQKVNELTGG 651
Query: 734 LESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEA---------LPEEKKIEYR----- 779
LE +KE + ++ K V K E+ + + E L EKK R
Sbjct: 652 LEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVF 711
Query: 780 -------LLKEEIANREKQ------------RLIKSDQ-------------LKTSSSSPA 807
+LKE I EK+ +L++++Q LK S +
Sbjct: 712 LSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVS 771
Query: 808 NSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESV--------------------L 847
E D + + V + + A+ +K + +DE V L
Sbjct: 772 EDSEEKDVVNVLQAVGESL--AKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEEL 829
Query: 848 KNLVQQEAKKKESVR--------NAEAKITKLTEQLQATEKILNVNRMFLKKLQE----- 894
K+L++ ++K +R EA + L E A EK N+ L +++E
Sbjct: 830 KSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTC 889
Query: 895 ---QIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLE----QDRFGPNKMMRLD 947
+IH +++ IK+ LK + KE+ R+ E +D + ++ D
Sbjct: 890 SKSEIHNEKEKCFIKEHENLK--------PLLEQKELRDRRAELILLKDSLAKSPSVKND 941
Query: 948 SSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKA--KEQQNISPVVEE-E 1004
P+SS ++ ++ +EK +K E +K+ +K + L + KE Q + +E
Sbjct: 942 --PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLR 999
Query: 1005 PEFSLPQPSLHDLTQ-----DKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLK 1059
E S+ DL Q L L+ E+ ++ +ER +F E
Sbjct: 1000 SEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDV----EKERANNF-EHRIEDLTRQL 1054
Query: 1060 HTDTANKECINKLNKN------TVEKPELFLGLKIGELQKLYSKAD 1099
T E IN N++ T++ L ++I E+Q+ + D
Sbjct: 1055 RNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD 1100
Score = 37.7 bits (86), Expect = 0.11
Identities = 95/471 (20%), Positives = 199/471 (42%), Gaps = 82/471 (17%)
Query: 717 SESDGEASKSTNSVFGGLES---MIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEE 773
SE D + S S + G ES ++ E + +EQ K E+ N+ E L
Sbjct: 1000 SEKD-QLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK-----ERANNFEHRIEDLT-- 1051
Query: 774 KKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRI-AMVTKQVT----D 828
+++ L+ E N + + L+ +++T S+ +V+I + R AMV K++
Sbjct: 1052 RQLRNSTLQCETINSDNEDLLA--RIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQ 1109
Query: 829 AESKLKKH----------RILLMKDESVLKNLVQQ-EAKKKES----------------V 861
E K+K+H ++ L K++ L+ +Q+ E KK++ +
Sbjct: 1110 KEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLM 1169
Query: 862 RNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRV-------TIKKALTLKYG 914
+ K+T +++ E+ + + + + LQE+I +Q V T K L +K
Sbjct: 1170 KELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTK 1229
Query: 915 EELARAKAVASKEI-------GKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKR 967
+ELA +K + + G+ + Q + ++ ++ + ++S + E +
Sbjct: 1230 KELADSKQAETDHLILQASLKGELEASQQQV---EVYKIQLAEITSEKHKIHEHLKTSAE 1286
Query: 968 RLQKLEYEYALKIQKL-KEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDT 1026
+ Q+ Y ++ L +E RA KA EQ ++ EF + +H++ + +
Sbjct: 1287 QHQRTLSAYQQRVTALQEECRAAKA-EQATVT------SEFESYKVRVHNVLKQQKNKSM 1339
Query: 1027 EENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVE-KPELFLG 1085
+ + + G+ +ER + + +K D+ N IN T++ + + L
Sbjct: 1340 SQAETE-----GAKQEREHLEM---LIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE 1391
Query: 1086 LKIGELQKLYSKADSLKQLILKTTTGITEKVLHGQEISVDVDFVTAQSKTM 1136
LQ+ SK L++ K + +E ++ E + V +T+Q++ +
Sbjct: 1392 RHNKMLQETVSKEAELRE---KLCSIQSENMMMKSEHTQTVSQLTSQNEVL 1439
Score = 37.0 bits (84), Expect = 0.19
Identities = 65/331 (19%), Positives = 130/331 (39%), Gaps = 40/331 (12%)
Query: 824 KQVTDAESKLKKHRILLMKDESVLKNL---VQQEAK--KKESVRNAEAKITKLTEQLQAT 878
K + D +L+ +L + + + NL ++ +A+ K E E K+ E L A
Sbjct: 335 KHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAK 394
Query: 879 EKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRF 938
E+ ++KL+ ++ + ++ ++ E+ K KEI +
Sbjct: 395 EE----QGCVIEKLKSELAGLNKQFCYTVE---QHNREVQSLKEQHQKEISEL------- 440
Query: 939 GPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNIS 998
N+ DS + + + LQ+ + E L + L+E + E +
Sbjct: 441 --NETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESA 498
Query: 999 PVVEEEPEFSLPQPS--LHDLTQDKLTLDTEENDVDDEI--LSGSSRERR---------- 1044
+ +E E Q + +H+L Q T TE++ + + + L G + +
Sbjct: 499 GKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELE 558
Query: 1045 ---RSFLESNYFTKPNLKHTDTANKECINKLNKNTVEKPELFLGLKIG--ELQKLYSKAD 1099
++ E N +L DT KE K+N T EK + LK E+ + K +
Sbjct: 559 NTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCE 618
Query: 1100 SLKQLILKTTTGITEKVLHGQEISVDVDFVT 1130
++LIL+ + + + + E+ V+ +T
Sbjct: 619 REERLILELGKKVEQTIQYNSELEQKVNELT 649
Score = 35.4 bits (80), Expect = 0.56
Identities = 75/348 (21%), Positives = 142/348 (40%), Gaps = 56/348 (16%)
Query: 230 LKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTD----NVSITKDSSKEV 285
L+ Q Q+E+ I E ++S++ + E KT + Q + V+ ++ +
Sbjct: 1253 LEASQQQVEVYKIQLAE---ITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAA 1309
Query: 286 APEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQ 345
E+ T F++++++ N LK+ K+ KS + ++G + + +
Sbjct: 1310 KAEQATVTSEFESYKVRV----------HNVLKQQKN-------KSMSQAETEGAKQERE 1352
Query: 346 NLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTK 405
+L I I KL + + + LQ+ + LQ+ Q E + E K+ + +
Sbjct: 1353 HLEMLIDQLKI----KLQDSQ---NNLQINVSELQTL-----QSEHDTLLERHNKMLQ-E 1399
Query: 406 TVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEER 465
TV ++ + K S + + ++ + T+ +L Q E R DQ + +EE
Sbjct: 1400 TVSKEAELREKLCSIQ----SENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHL-QEEH 1454
Query: 466 RKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSG-GGIYQ 524
RK E ++ + LS E Q +L SS L+ +++ TD ++
Sbjct: 1455 RKTVETLQ--QQLSKMEAQ---LFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHT 1509
Query: 525 YDNYEEVAMD-TDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPP 571
E M+ TD+E+ S A + Q SL +P L PP
Sbjct: 1510 VTREEGEGMETTDTESVSSASTYTQ-------SLEQLLNSPETKLEPP 1550
Score = 34.3 bits (77), Expect = 1.2
Identities = 59/287 (20%), Positives = 127/287 (44%), Gaps = 15/287 (5%)
Query: 210 KQNYSSKNENCVEETFEDLLLKYKQIQ-LELECIN-KDEKLALSSKEENVQEDPKTLNFE 267
++ S NE + ++ ++ L +IQ L+ +C N + EK E+++E + L E
Sbjct: 434 QKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTE 493
Query: 268 DQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPL 327
S +S +S K+ ++ + V Q +K L NRL+ + K L
Sbjct: 494 LGESAGKISQEFESMKQ---QQASDVHELQQKLRTAFTEKDALLETVNRLQG--ENEKLL 548
Query: 328 S---LKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASK 384
S L + ++ + LQ+K +S D + ++ G+ E + L+++ +
Sbjct: 549 SQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHE 608
Query: 385 KWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQ 444
+ ++ +E + L K V+Q ++ +++ T + K++ + +KL++
Sbjct: 609 EMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEK 668
Query: 445 QKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKL 491
Q + ED K+ E + EE K LS++++Q +R +++
Sbjct: 669 LMVQMKVLSED--KEVLSAEVKSLYEENNK---LSSEKKQLSRDLEV 710
Score = 33.5 bits (75), Expect = 2.1
Identities = 65/296 (21%), Positives = 129/296 (43%), Gaps = 45/296 (15%)
Query: 226 EDLLLKYKQIQLELEC-INKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKE 284
ED++LK QLE + + +E+ L+ EN Q + T K+ E
Sbjct: 716 EDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVK------TQLYGFLKEMGSE 769
Query: 285 VAP--EEKTQVKTFQAFE---LKPLRQKLTLPGDKNRLKKVKDGAKPLS-LKSDTTDSSQ 338
V+ EEK V QA K +K L ++ +KV + K + L+ ++ +
Sbjct: 770 VSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRD--EKVLELEKEIKCLQEESVVQCE 827
Query: 339 GLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESK 398
L+ +L R +L K+L E + E LQ LL +++A++K + + Q ++ + +
Sbjct: 828 ELK----SLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVE 883
Query: 399 EKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKE----E 454
E ++T S ++ ++ K+ L+Q++ ++R+ E +
Sbjct: 884 EV--------------SQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLK 929
Query: 455 DQRKQAEEEER------RKREEEIRKI-RDLSNQEEQYNRFMKLVGGKRRSRSKSS 503
D ++ + ++ EE+I + ++ +EE+ N+ +KLV K + SS
Sbjct: 930 DSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINK-IKLVAVKAKKELDSS 984
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,830,375
Number of Sequences: 37866
Number of extensions: 4345374
Number of successful extensions: 62615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 674
Number of HSP's successfully gapped in prelim test: 1860
Number of HSP's that attempted gapping in prelim test: 28091
Number of HSP's gapped (non-prelim): 18369
length of query: 1989
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1872
effective length of database: 13,817,196
effective search space: 25865790912
effective search space used: 25865790912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.