Guide to the Human Genome
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Search of human proteins with 85362735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|85362735 nuclear receptor subfamily 1, group H, member 2
[Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom...   936   0.0  
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   538   e-153
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   537   e-153
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   244   1e-64
gi|194328806 nuclear receptor subfamily 1, group H, member 3 iso...   231   1e-60
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     206   5e-53
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   204   1e-52
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     204   1e-52
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    202   7e-52
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   199   6e-51
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...   197   1e-50
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...   197   1e-50
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            194   2e-49
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            194   2e-49
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             194   2e-49
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]     191   1e-48
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   185   9e-47
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   180   3e-45
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   175   7e-44
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   175   9e-44
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   170   3e-42
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   165   9e-41
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   164   2e-40
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  160   2e-39
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   158   9e-39
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]    154   1e-37
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]    154   2e-37
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]     154   2e-37
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]    154   2e-37
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   152   8e-37

>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
           sapiens]
          Length = 461

 Score =  936 bits (2418), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW 60
           MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
Sbjct: 1   MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW 60

Query: 61  VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA 120
           VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
Sbjct: 61  VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA 120

Query: 121 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS 180
           RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS
Sbjct: 121 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS 180

Query: 181 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK 240
           QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK
Sbjct: 181 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK 240

Query: 241 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ 300
           RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ
Sbjct: 241 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ 300

Query: 301 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM 360
           IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM
Sbjct: 301 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM 360

Query: 361 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR 420
           RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR
Sbjct: 361 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR 420

Query: 421 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 461
           MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Sbjct: 421 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 461


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  538 bits (1387), Expect = e-153
 Identities = 287/461 (62%), Positives = 339/461 (73%), Gaps = 29/461 (6%)

Query: 4   PTTSSLDTPLPGNGPPQPGAPSSSPTV-KEEGPEPWPGGPDPDVPGTDEASSACSTDWVI 62
           P  S+++   PG       A   S  + +EE   P   G    V G + A          
Sbjct: 13  PPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGV-GLEAAEPTALLTRAE 71

Query: 63  P--DPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA 120
           P  +P E   +KRKKGPAPKMLG+ELC VCGDKASGFHYNVLSCEGCKGFFRRSV++G  
Sbjct: 72  PPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGA- 130

Query: 121 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS 180
             Y C  GG C MD +MRRKCQ+CRLRKC++AGMRE+CVLSEEQIR KK+++Q+++++ +
Sbjct: 131 -HYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHA 189

Query: 181 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK 240
            S  P        ++S P   P                QL+  Q  MI++LVAAQ QCN+
Sbjct: 190 TSLPP-------RASSPPQILP----------------QLSPEQLGMIEKLVAAQQQCNR 226

Query: 241 RSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQ 300
           RSFSD+ +VTPWP+  DP SR+ARQQRFAHFTELAI+SVQEIVDFAKQ+PGFLQL REDQ
Sbjct: 227 RSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQ 286

Query: 301 IALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAM 360
           IALLK S IE+MLLET+RRYN  +E ITFLKDF+Y+++DF +AGLQVEFINPIFEFSRAM
Sbjct: 287 IALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAM 346

Query: 361 RRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPR 420
             L L+DAE+ALLIAI+IFSADRPNVQ+  +VE LQ  YVEAL +Y  I  P D+L FPR
Sbjct: 347 NELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPR 406

Query: 421 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 461
           MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Sbjct: 407 MLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 447


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  537 bits (1383), Expect = e-153
 Identities = 273/398 (68%), Positives = 319/398 (80%), Gaps = 25/398 (6%)

Query: 64  DPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRY 123
           +P E   +KRKKGPAPKMLG+ELC VCGDKASGFHYNVLSCEGCKGFFRRSV++G    Y
Sbjct: 30  EPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGA--HY 87

Query: 124 ACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQ 183
            C  GG C MD +MRRKCQ+CRLRKC++AGMRE+CVLSEEQIR KK+++Q+++++ + S 
Sbjct: 88  ICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSL 147

Query: 184 SPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSF 243
            P        ++S P   P                QL+  Q  MI++LVAAQ QCN+RSF
Sbjct: 148 PP-------RASSPPQILP----------------QLSPEQLGMIEKLVAAQQQCNRRSF 184

Query: 244 SDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIAL 303
           SD+ +VTPWP+  DP SR+ARQQRFAHFTELAI+SVQEIVDFAKQ+PGFLQL REDQIAL
Sbjct: 185 SDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIAL 244

Query: 304 LKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRL 363
           LK S IE+MLLET+RRYN  +E ITFLKDF+Y+++DF +AGLQVEFINPIFEFSRAM  L
Sbjct: 245 LKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNEL 304

Query: 364 GLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLM 423
            L+DAE+ALLIAI+IFSADRPNVQ+  +VE LQ  YVEAL +Y  I  P D+L FPRMLM
Sbjct: 305 QLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLM 364

Query: 424 KLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 461
           KLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Sbjct: 365 KLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 402


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  244 bits (623), Expect = 1e-64
 Identities = 142/390 (36%), Positives = 215/390 (55%), Gaps = 28/390 (7%)

Query: 70  ERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGG 129
           ++ R    A ++ G ELC VCGD+ASG+HYN L+CEGCKGFFRRS+ +     Y C+ GG
Sbjct: 110 KKPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAV--YKCKNGG 167

Query: 130 TCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQ 189
            C MD +MRRKCQ+CRLRKCKE GM  +C+L+E Q + K++RK  +Q +          Q
Sbjct: 168 NCVMDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHAD---------Q 218

Query: 190 GSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKV 249
             +  + G        +  S      E  +LT  Q+ ++  ++ +    NK+    +  +
Sbjct: 219 TVNEDSEGRDL----RQVTSTTKSCREKTELTPDQQTLLHFIMDSY---NKQRMPQE--I 269

Query: 250 TPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTI 309
           T   L    +   + ++ F   TE+A   VQ +V+F K++PGF  L  EDQIALLK S +
Sbjct: 270 TNKIL----KEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAV 325

Query: 310 EIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAE 369
           E M L +A  +N +             ++    +G+  E+I P+F F +++  L +   E
Sbjct: 326 EAMFLRSAEIFNKKLPS----GHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEE 381

Query: 370 YALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLR 429
           YALL AI I S DR  +++   VE LQ+P ++ L    +I +P++   F  +L +L  LR
Sbjct: 382 YALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELR 441

Query: 430 TLSSVHSEQVFALRLQDKKLPPLLSEIWDV 459
           T +  H+E + + R+ D K  PLL EIWDV
Sbjct: 442 TFNHHHAEMLMSWRVNDHKFTPLLCEIWDV 471


>gi|194328806 nuclear receptor subfamily 1, group H, member 3
           isoform b [Homo sapiens]
          Length = 387

 Score =  231 bits (589), Expect = 1e-60
 Identities = 117/153 (76%), Positives = 133/153 (86%)

Query: 309 IEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDA 368
           + +MLLET+RRYN  +E ITFLKDF+Y+++DF +AGLQVEFINPIFEFSRAM  L L+DA
Sbjct: 235 VTVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDA 294

Query: 369 EYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSL 428
           E+ALLIAI+IFSADRPNVQ+  +VE LQ  YVEAL +Y  I  P D+L FPRMLMKLVSL
Sbjct: 295 EFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSL 354

Query: 429 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 461
           RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Sbjct: 355 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 387



 Score =  211 bits (537), Expect = 1e-54
 Identities = 120/250 (48%), Positives = 153/250 (61%), Gaps = 29/250 (11%)

Query: 4   PTTSSLDTPLPGNGPPQPGAPSSSPTV-KEEGPEPWPGGPDPDVPGTDEASSACSTDWVI 62
           P  S+++   PG       A   S  + +EE   P   G    V G + A          
Sbjct: 13  PPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGV-GLEAAEPTALLTRAE 71

Query: 63  P--DPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA 120
           P  +P E   +KRKKGPAPKMLG+ELC VCGDKASGFHYNVLSCEGCKGFFRRSV++G  
Sbjct: 72  PPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGA- 130

Query: 121 RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQS 180
             Y C  GG C MD +MRRKCQ+CRLRKC++AGMRE+CVLSEEQIR KK+++Q+++++ +
Sbjct: 131 -HYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHA 189

Query: 181 QSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNK 240
            S  P        ++S P   P                QL+  Q  MI++LVAAQ QCN+
Sbjct: 190 TSLPP-------RASSPPQILP----------------QLSPEQLGMIEKLVAAQQQCNR 226

Query: 241 RSFSDQPKVT 250
           RSFSD+ +VT
Sbjct: 227 RSFSDRLRVT 236


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  206 bits (523), Expect = 5e-53
 Identities = 138/454 (30%), Positives = 222/454 (48%), Gaps = 65/454 (14%)

Query: 14  PGNGPPQPGAPSSSPTVKEEGPE------PWPGGPDPDVPGTDEASSACSTDWVIPDPEE 67
           PG+G P  G P + P      P        + G   PD+P   +  ++ S +      EE
Sbjct: 16  PGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLP---KEMASLSVETQSTSSEE 72

Query: 68  EPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRG 127
                    P P++  ++ C VC DK+SG+HY V SCEGCKGFFRRS+ +     Y C  
Sbjct: 73  MVPSSPSPPPPPRV--YKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMV--YTCHR 128

Query: 128 GGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVG 187
              C ++   R +CQ CRL+KC E GM ++ V ++   +KK+++++   +S   S     
Sbjct: 129 DKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELS----- 183

Query: 188 PQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQP 247
           PQ                                      +++L+    + ++ +F    
Sbjct: 184 PQ--------------------------------------LEELITKVSKAHQETFPSLC 205

Query: 248 KVTPWPLGADPQSRDARQQR----FAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIAL 303
           ++  +   +   S D R Q     +  F+ELA   + +IV+FAK++PGF  L   DQI L
Sbjct: 206 QLGKYTTNS---SADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITL 262

Query: 304 LKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRL 363
           LKA+ ++I++L    RY  E + +TF    T ++   H AG      + +F F+  +  L
Sbjct: 263 LKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG-PLTDLVFAFAGQLLPL 321

Query: 364 GLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLM 423
            +DD E  LL AI +   DR +++EP +V+ LQ+P +EAL  Y R +RP     FPRMLM
Sbjct: 322 EMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLM 381

Query: 424 KLVSLRTLSSVHSEQVFALRLQ-DKKLPPLLSEI 456
           K+  LR +S+  +E+   L+++    +PPL+ E+
Sbjct: 382 KITDLRGISTKGAERAITLKMEIPGPMPPLIREM 415


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  204 bits (519), Expect = 1e-52
 Identities = 145/474 (30%), Positives = 226/474 (47%), Gaps = 76/474 (16%)

Query: 6   TSSLDTPLPGNG--------------PPQPGA---PSSSPTVKEEGPEPWPGGPDPDVPG 48
           ++S   P PG G              PP  G    P +  T++ + P      P P    
Sbjct: 3   SNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIE 62

Query: 49  TDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCK 108
           T  +SS    + ++P P   P       P P++  ++ C VC DK+SG+HY V +CEGCK
Sbjct: 63  TQSSSS----EEIVPSPPSPP-------PLPRI--YKPCFVCQDKSSGYHYGVSACEGCK 109

Query: 109 GFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKK 168
           GFFRRS+ +     Y C     C ++   R +CQ CRL+KC E GM ++ V ++   +KK
Sbjct: 110 GFFRRSIQKNMV--YTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKK 167

Query: 169 KIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMI 228
           ++ K               P+ S S    P       E G          +L        
Sbjct: 168 EVPK---------------PECSESYTLTP-------EVG----------ELIEKVRKAH 195

Query: 229 QQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQ 288
           Q+   A  Q  K + ++  +          Q        +  F+EL+   + + V+FAKQ
Sbjct: 196 QETFPALCQLGKYTTNNSSE----------QRVSLDIDLWDKFSELSTKCIIKTVEFAKQ 245

Query: 289 VPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVE 348
           +PGF  L   DQI LLKA+ ++I++L    RY  E + +TF    T ++   H AG    
Sbjct: 246 LPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG-P 304

Query: 349 FINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR 408
             + +F F+  +  L +DDAE  LL AI +   DR ++++P RV+ LQ+P +EAL  Y R
Sbjct: 305 LTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR 364

Query: 409 IKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQ-DKKLPPLLSEIWDVHE 461
            +RP     FP+MLMK+  LR++S+  +E+V  L+++    +PPL+ E+ +  E
Sbjct: 365 KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE 418


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  204 bits (519), Expect = 1e-52
 Identities = 145/474 (30%), Positives = 226/474 (47%), Gaps = 76/474 (16%)

Query: 6   TSSLDTPLPGNG--------------PPQPGA---PSSSPTVKEEGPEPWPGGPDPDVPG 48
           ++S   P PG G              PP  G    P +  T++ + P      P P    
Sbjct: 3   SNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIE 62

Query: 49  TDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCK 108
           T  +SS    + ++P P   P       P P++  ++ C VC DK+SG+HY V +CEGCK
Sbjct: 63  TQSSSS----EEIVPSPPSPP-------PLPRI--YKPCFVCQDKSSGYHYGVSACEGCK 109

Query: 109 GFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKK 168
           GFFRRS+ +     Y C     C ++   R +CQ CRL+KC E GM ++ V ++   +KK
Sbjct: 110 GFFRRSIQKNMV--YTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKK 167

Query: 169 KIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMI 228
           ++ K               P+ S S    P       E G          +L        
Sbjct: 168 EVPK---------------PECSESYTLTP-------EVG----------ELIEKVRKAH 195

Query: 229 QQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQ 288
           Q+   A  Q  K + ++  +          Q        +  F+EL+   + + V+FAKQ
Sbjct: 196 QETFPALCQLGKYTTNNSSE----------QRVSLDIDLWDKFSELSTKCIIKTVEFAKQ 245

Query: 289 VPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVE 348
           +PGF  L   DQI LLKA+ ++I++L    RY  E + +TF    T ++   H AG    
Sbjct: 246 LPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG-P 304

Query: 349 FINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR 408
             + +F F+  +  L +DDAE  LL AI +   DR ++++P RV+ LQ+P +EAL  Y R
Sbjct: 305 LTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR 364

Query: 409 IKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQ-DKKLPPLLSEIWDVHE 461
            +RP     FP+MLMK+  LR++S+  +E+V  L+++    +PPL+ E+ +  E
Sbjct: 365 KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE 418


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  202 bits (513), Expect = 7e-52
 Identities = 141/450 (31%), Positives = 221/450 (49%), Gaps = 66/450 (14%)

Query: 13  LPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERK 72
           LP  G P PG P S+P        P   G +  +      + + S++ ++P P   P   
Sbjct: 29  LPEKGLPAPG-PYSTPL-----RTPLWNGSNHSIE-----TQSSSSEEIVPSPPSPP--- 74

Query: 73  RKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQ 132
               P P++  ++ C VC DK+SG+HY V +CEGCKGFFRRS+ +     Y C     C 
Sbjct: 75  ----PLPRI--YKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMV--YTCHRDKNCI 126

Query: 133 MDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSS 192
           ++   R +CQ CRL+KC E GM ++ V ++   +KK++ K               P+ S 
Sbjct: 127 INKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPK---------------PECSE 171

Query: 193 SSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPW 252
           S    P       E G          +L        Q+   A  Q  K + ++  +    
Sbjct: 172 SYTLTP-------EVG----------ELIEKVRKAHQETFPALCQLGKYTTNNSSE---- 210

Query: 253 PLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIM 312
                 Q        +  F+EL+   + + V+FAKQ+PGF  L   DQI LLKA+ ++I+
Sbjct: 211 ------QRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDIL 264

Query: 313 LLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYAL 372
           +L    RY  E + +TF    T ++   H AG      + +F F+  +  L +DDAE  L
Sbjct: 265 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG-PLTDLVFAFANQLLPLEMDDAETGL 323

Query: 373 LIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLS 432
           L AI +   DR ++++P RV+ LQ+P +EAL  Y R +RP     FP+MLMK+  LR++S
Sbjct: 324 LSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSIS 383

Query: 433 SVHSEQVFALRLQ-DKKLPPLLSEIWDVHE 461
           +  +E+V  L+++    +PPL+ E+ +  E
Sbjct: 384 AKGAERVITLKMEIPGSMPPLIQEMLENSE 413


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  199 bits (505), Expect = 6e-51
 Identities = 130/420 (30%), Positives = 206/420 (49%), Gaps = 64/420 (15%)

Query: 42  PDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNV 101
           P P    + E  S  S + V   P           P P    ++ C VC DK+SG+HY V
Sbjct: 44  PQPASLQSVETQSTSSEEMVPSSPS----------PPPPPRVYKPCFVCNDKSSGYHYGV 93

Query: 102 LSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLS 161
            SCEGCKGFFRRS+ +     Y C     C ++   R +CQ CRL+KC E GM ++ V +
Sbjct: 94  SSCEGCKGFFRRSIQKNMV--YTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRN 151

Query: 162 EEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLT 221
           +   +KK+++++   +S   S     PQ                                
Sbjct: 152 DRNKKKKEVKEEGSPDSYELS-----PQ-------------------------------- 174

Query: 222 AAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQR----FAHFTELAII 277
                 +++L+    + ++ +F    ++  +   +   S D R Q     +  F+ELA  
Sbjct: 175 ------LEELITKVSKAHQETFPSLCQLGKYTTNS---SADHRVQLDLGLWDKFSELATK 225

Query: 278 SVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSK 337
            + +IV+FAK++PGF  L   DQI LLKA+ ++I++L    RY  E + +TF    T ++
Sbjct: 226 CIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR 285

Query: 338 DDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQ 397
              H AG      + +F F+  +  L +DD E  LL AI +   DR +++EP +V+ LQ+
Sbjct: 286 TQMHNAGFG-PLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQE 344

Query: 398 PYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQ-DKKLPPLLSEI 456
           P +EAL  Y R +RP     FPRMLMK+  LR +S+  +E+   L+++    +PPL+ E+
Sbjct: 345 PLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREM 404


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  197 bits (502), Expect = 1e-50
 Identities = 128/415 (30%), Positives = 209/415 (50%), Gaps = 58/415 (13%)

Query: 86  LCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCR 145
           +C VCGD+A+GFH+N ++CEGCKGFFRRS+ R     + C   G C++    RR CQ CR
Sbjct: 23  ICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKAL--FTCPFNGDCRITKDNRRHCQACR 80

Query: 146 LRKCKEAGMREQCVLSEEQIRKKK--IRKQQQQESQSQSQSPVGPQ-------------- 189
           L++C + GM ++ +L++E++++K+  I K++++E+   S  P   +              
Sbjct: 81  LKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHH 140

Query: 190 ---------------------GSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMI 228
                                G  S  S P +    S +G   S   +   +T++   M+
Sbjct: 141 KTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHC-ITSSD--MM 197

Query: 229 QQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQ 288
                + L  ++   SD P VT            ++     H  +L   S+Q+++ FAK 
Sbjct: 198 DSSSFSNLDLSEED-SDDPSVT---------LELSQLSMLPHLADLVSYSIQKVIGFAKM 247

Query: 289 VPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITF-LKDFTYSKDDFHRAGLQV 347
           +PGF  L  EDQI LLK+S IE+++L +   +  +    T   +D+ Y   D  +AG  +
Sbjct: 248 IPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSL 307

Query: 348 EFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYT 407
           E I P+ +F   +++L L + E+ LL+AI I S DRP VQ+   +EA+Q      L +Y 
Sbjct: 308 ELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYI 367

Query: 408 RIKRPQ--DQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDK---KLPPLLSEIW 457
           R + P     L + +M+ KL  LR+L+  HS+Q   L  Q +   KL PL+ E++
Sbjct: 368 RCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVF 422


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  197 bits (502), Expect = 1e-50
 Identities = 128/415 (30%), Positives = 209/415 (50%), Gaps = 58/415 (13%)

Query: 86  LCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCR 145
           +C VCGD+A+GFH+N ++CEGCKGFFRRS+ R     + C   G C++    RR CQ CR
Sbjct: 23  ICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKAL--FTCPFNGDCRITKDNRRHCQACR 80

Query: 146 LRKCKEAGMREQCVLSEEQIRKKK--IRKQQQQESQSQSQSPVGPQ-------------- 189
           L++C + GM ++ +L++E++++K+  I K++++E+   S  P   +              
Sbjct: 81  LKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHH 140

Query: 190 ---------------------GSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMI 228
                                G  S  S P +    S +G   S   +   +T++   M+
Sbjct: 141 KTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHC-ITSSD--MM 197

Query: 229 QQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQ 288
                + L  ++   SD P VT            ++     H  +L   S+Q+++ FAK 
Sbjct: 198 DSSSFSNLDLSEED-SDDPSVT---------LELSQLSMLPHLADLVSYSIQKVIGFAKM 247

Query: 289 VPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITF-LKDFTYSKDDFHRAGLQV 347
           +PGF  L  EDQI LLK+S IE+++L +   +  +    T   +D+ Y   D  +AG  +
Sbjct: 248 IPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSL 307

Query: 348 EFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYT 407
           E I P+ +F   +++L L + E+ LL+AI I S DRP VQ+   +EA+Q      L +Y 
Sbjct: 308 ELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYI 367

Query: 408 RIKRPQ--DQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDK---KLPPLLSEIW 457
           R + P     L + +M+ KL  LR+L+  HS+Q   L  Q +   KL PL+ E++
Sbjct: 368 RCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVF 422


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  194 bits (492), Expect = 2e-49
 Identities = 117/396 (29%), Positives = 198/396 (50%), Gaps = 27/396 (6%)

Query: 68  EPERKRKKGPAPKMLGH-ELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACR 126
           + E K+ KG  P  L   ELC VCGDKA+G+HY  ++CEGCKGFFRR++ +     Y+C+
Sbjct: 87  QTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCK 146

Query: 127 GGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQ--IRKKKIRKQQQQESQSQSQS 184
             G C +D   R +CQ+CR +KC   GM    VL + +   ++K I + +++  + + Q 
Sbjct: 147 YEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQK 206

Query: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244
            +G +   +                    + E   +    E  +           KR F 
Sbjct: 207 SIGHKPEPT--------------------DEEWELIKTVTEAHVATNAQGSHWKQKRKFL 246

Query: 245 DQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALL 304
            +  +   P+   P+      + F+HFT++   ++  +VDFAK++P F +L  EDQI LL
Sbjct: 247 PED-IGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILL 305

Query: 305 KASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLG 364
           K   +EIM L  A RY+ E+E +T   +   ++      GL V   + IF+   ++    
Sbjct: 306 KGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFN 364

Query: 365 LDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMK 424
           LDD E ALL A+ + S+DRP +    R+E  Q  ++ A   Y   ++      +P++LMK
Sbjct: 365 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK 424

Query: 425 LVSLRTLSSVHSEQVFALRLQ--DKKLPPLLSEIWD 458
           +  LR + + H+ +   ++++   +  PPL  E+++
Sbjct: 425 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFE 460


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  194 bits (492), Expect = 2e-49
 Identities = 117/396 (29%), Positives = 198/396 (50%), Gaps = 27/396 (6%)

Query: 68  EPERKRKKGPAPKMLGH-ELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACR 126
           + E K+ KG  P  L   ELC VCGDKA+G+HY  ++CEGCKGFFRR++ +     Y+C+
Sbjct: 87  QTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCK 146

Query: 127 GGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQ--IRKKKIRKQQQQESQSQSQS 184
             G C +D   R +CQ+CR +KC   GM    VL + +   ++K I + +++  + + Q 
Sbjct: 147 YEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQK 206

Query: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244
            +G +   +                    + E   +    E  +           KR F 
Sbjct: 207 SIGHKPEPT--------------------DEEWELIKTVTEAHVATNAQGSHWKQKRKFL 246

Query: 245 DQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALL 304
            +  +   P+   P+      + F+HFT++   ++  +VDFAK++P F +L  EDQI LL
Sbjct: 247 PED-IGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILL 305

Query: 305 KASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLG 364
           K   +EIM L  A RY+ E+E +T   +   ++      GL V   + IF+   ++    
Sbjct: 306 KGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFN 364

Query: 365 LDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMK 424
           LDD E ALL A+ + S+DRP +    R+E  Q  ++ A   Y   ++      +P++LMK
Sbjct: 365 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK 424

Query: 425 LVSLRTLSSVHSEQVFALRLQ--DKKLPPLLSEIWD 458
           +  LR + + H+ +   ++++   +  PPL  E+++
Sbjct: 425 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFE 460


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  194 bits (492), Expect = 2e-49
 Identities = 117/396 (29%), Positives = 198/396 (50%), Gaps = 27/396 (6%)

Query: 68  EPERKRKKGPAPKMLGH-ELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACR 126
           + E K+ KG  P  L   ELC VCGDKA+G+HY  ++CEGCKGFFRR++ +     Y+C+
Sbjct: 87  QTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCK 146

Query: 127 GGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQ--IRKKKIRKQQQQESQSQSQS 184
             G C +D   R +CQ+CR +KC   GM    VL + +   ++K I + +++  + + Q 
Sbjct: 147 YEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQK 206

Query: 185 PVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFS 244
            +G +   +                    + E   +    E  +           KR F 
Sbjct: 207 SIGHKPEPT--------------------DEEWELIKTVTEAHVATNAQGSHWKQKRKFL 246

Query: 245 DQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALL 304
            +  +   P+   P+      + F+HFT++   ++  +VDFAK++P F +L  EDQI LL
Sbjct: 247 PED-IGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILL 305

Query: 305 KASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLG 364
           K   +EIM L  A RY+ E+E +T   +   ++      GL V   + IF+   ++    
Sbjct: 306 KGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGV-VSDAIFDLGMSLSSFN 364

Query: 365 LDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMK 424
           LDD E ALL A+ + S+DRP +    R+E  Q  ++ A   Y   ++      +P++LMK
Sbjct: 365 LDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMK 424

Query: 425 LVSLRTLSSVHSEQVFALRLQ--DKKLPPLLSEIWD 458
           +  LR + + H+ +   ++++   +  PPL  E+++
Sbjct: 425 VTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFE 460


>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
          Length = 448

 Score =  191 bits (485), Expect = 1e-48
 Identities = 123/411 (29%), Positives = 208/411 (50%), Gaps = 57/411 (13%)

Query: 53  SSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFR 112
           + + S++ ++P P           P P    ++ C VC DK+SG+HY V +CEGCKGFFR
Sbjct: 56  TQSTSSEELVPSPPS---------PLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFR 106

Query: 113 RSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRK 172
           RS+ +     Y C     C ++   R +CQ CRL+KC E GM      S+E +R  + +K
Sbjct: 107 RSIQKNMI--YTCHRDKNCVINKVTRNRCQYCRLQKCFEVGM------SKESVRNDRNKK 158

Query: 173 QQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLV 232
           +++   Q  ++S                                  ++TA  + + +++ 
Sbjct: 159 KKETSKQECTES---------------------------------YEMTAELDDLTEKIR 185

Query: 233 AAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQR-FAHFTELAIISVQEIVDFAKQVPG 291
            A    ++ +F    ++  +   +    R       +  F+ELA   + +IV+FAK++PG
Sbjct: 186 KA----HQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPG 241

Query: 292 FLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFIN 351
           F  L   DQI LLKA+ ++I++L    RY  E + +TF    T ++   H AG      +
Sbjct: 242 FTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG-PLTD 300

Query: 352 PIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKR 411
            +F F+  +  L +DD E  LL AI +   DR +++EP +V+ LQ+P +EAL  Y R +R
Sbjct: 301 LVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRR 360

Query: 412 PQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQ-DKKLPPLLSEIWDVHE 461
           P     FP++LMK+  LR++S+  +E+V  L+++    +PPL+ E+ +  E
Sbjct: 361 PSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSE 411


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  185 bits (469), Expect = 9e-47
 Identities = 125/396 (31%), Positives = 211/396 (53%), Gaps = 57/396 (14%)

Query: 83  GHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQ 142
           G ++CRVCGDKA+G+H+NV++CEGCKGFFRR++ R    R   R G  C++    RR+CQ
Sbjct: 37  GPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGA-CEITRKTRRQCQ 95

Query: 143 QCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASP 202
            CRLRKC E+GM+++ ++S+E + +++   ++++  ++ +Q P+G QG            
Sbjct: 96  ACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQ-PLGVQG------------ 142

Query: 203 GGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQP--KVTPWPLGAD--- 257
                            LT  Q +MI++L+ AQ++    +FS     +V+    G D   
Sbjct: 143 -----------------LTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185

Query: 258 ----PQSRDARQQRFA---HFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIE 310
               P +    ++ F+   H  +++    + I+ FAK +  F  L  EDQI+LLK +  E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245

Query: 311 IMLLETARRYNHET---ECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDD 367
           +  L     +N ET   EC       +Y  +D    G Q   + P+ +F   +++L L +
Sbjct: 246 LCQLRFNTVFNAETGTWEC----GRLSYCLEDT-AGGFQQLLLEPMLKFHYMLKKLQLHE 300

Query: 368 AEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLR--FPRMLMKL 425
            EY L+ AI++FS DRP V +   V+ LQ+ +   L SY    RPQ   R  F +++  L
Sbjct: 301 EEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAML 360

Query: 426 VSLRTLSSVHSEQVFALRLQD--KKLPPLLSEIWDV 459
             LR++++ H++++  LR+QD      PL+ E++ +
Sbjct: 361 TELRSINAQHTQRL--LRIQDIHPFATPLMQELFGI 394


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  180 bits (456), Expect = 3e-45
 Identities = 119/418 (28%), Positives = 201/418 (48%), Gaps = 41/418 (9%)

Query: 64  DPEE------EPERKRKKGPAP---KMLGH--------ELCRVCGDKASGFHYNVLSCEG 106
           DPEE      + +RKRK G       M G+        E C VCGDKA+G+HY  ++CEG
Sbjct: 13  DPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEG 72

Query: 107 CKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSE-EQI 165
           CKGFFRR++ +     Y+C+    C +D   R +CQ CR +KC   GM    VL + +++
Sbjct: 73  CKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRV 132

Query: 166 RKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQE 225
            K+K+ +Q ++  + +       Q    +          +EA    + +G   +      
Sbjct: 133 AKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWK------ 186

Query: 226 LMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDF 285
                         +R F     +   P+ + P       + F+ FT++   ++  +VDF
Sbjct: 187 -------------QRRKFLPDD-IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDF 232

Query: 286 AKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGL 345
           AK++P F +L  EDQI LLK   +EIM L  A RY+ E++ +T   +    ++     GL
Sbjct: 233 AKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGL 292

Query: 346 QVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLS 405
            V   + IFE  +++    LDD E ALL A+ + S DR  +    ++E  Q+ Y+ A   
Sbjct: 293 GV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEH 351

Query: 406 YTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQ--DKKLPPLLSEIWDVHE 461
           Y   ++      +P++LMK+  LR + + H+ +   ++++   +  PPL  E+++  E
Sbjct: 352 YVNHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQE 409


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  175 bits (444), Expect = 7e-44
 Identities = 130/455 (28%), Positives = 223/455 (49%), Gaps = 51/455 (11%)

Query: 39  PGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFH 98
           P GP+ ++    + S     D+V  +  E    K       ++ G ++CRVCGDKA+G+H
Sbjct: 33  PRGPEANLEVRPKESWN-HADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYH 91

Query: 99  YNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQC 158
           +NV++CEGCKGFFRR++ R    R   R  G C++    RR+CQ CRLRKC E+GM+++ 
Sbjct: 92  FNVMTCEGCKGFFRRAMKRNARLRCPFR-KGACEITRKTRRQCQACRLRKCLESGMKKEM 150

Query: 159 VLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASG--------------------- 197
           ++S+E + +++   ++++  ++ +Q P+G QG +                          
Sbjct: 151 IMSDEAVEERRALIKRKKSERTGTQ-PLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFK 209

Query: 198 ----PGASPGGSE--AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTP 251
               PG    G E     Q     E  + +  ++ +    V+ QL+       +   V  
Sbjct: 210 NFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLR------GEDGSVWN 263

Query: 252 WPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEI 311
           +   AD   ++       H  +++    + I+ FAK +  F  L  EDQI+LLK +  E+
Sbjct: 264 YKPPADSGGKEI-FSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFEL 322

Query: 312 MLLETARRYNHET---ECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDA 368
             L     +N ET   EC       +Y  +D    G Q   + P+ +F   +++L L + 
Sbjct: 323 CQLRFNTVFNAETGTWEC----GRLSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEE 377

Query: 369 EYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLR--FPRMLMKLV 426
           EY L+ AI++FS DRP V +   V+ LQ+ +   L SY    RPQ   R  F +++  L 
Sbjct: 378 EYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLT 437

Query: 427 SLRTLSSVHSEQVFALRLQD--KKLPPLLSEIWDV 459
            LR++++ H++++  LR+QD      PL+ E++ +
Sbjct: 438 ELRSINAQHTQRL--LRIQDIHPFATPLMQELFGI 470


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  175 bits (443), Expect = 9e-44
 Identities = 122/411 (29%), Positives = 207/411 (50%), Gaps = 50/411 (12%)

Query: 83  GHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQ 142
           G ++CRVCGDKA+G+H+NV++CEGCKGFFRR++ R    R   R  G C++    RR+CQ
Sbjct: 37  GPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFR-KGACEITRKTRRQCQ 95

Query: 143 QCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASG----- 197
            CRLRKC E+GM+++ ++S+E + +++   ++++  ++ +Q P+G QG +          
Sbjct: 96  ACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQ-PLGVQGLTEEQRMMIREL 154

Query: 198 --------------------PGASPGGSE--AGSQGSGEGEGVQLTAAQELMIQQLVAAQ 235
                               PG    G E     Q     E  + +  ++ +    V+ Q
Sbjct: 155 MDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQ 214

Query: 236 LQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQL 295
           L+       +   V  +   AD   ++       H  +++    + I+ FAK +  F  L
Sbjct: 215 LR------GEDGSVWNYKPPADSGGKEI-FSLLPHMADMSTYMFKGIISFAKVISYFRDL 267

Query: 296 GREDQIALLKASTIEIMLLETARRYNHET---ECITFLKDFTYSKDDFHRAGLQVEFINP 352
             EDQI+LLK +  E+  L     +N ET   EC       +Y  +D    G Q   + P
Sbjct: 268 PIEDQISLLKGAAFELCQLRFNTVFNAETGTWEC----GRLSYCLED-TAGGFQQLLLEP 322

Query: 353 IFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRP 412
           + +F   +++L L + EY L+ AI++FS DRP V +   V+ LQ+ +   L SY    RP
Sbjct: 323 MLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRP 382

Query: 413 QDQLR--FPRMLMKLVSLRTLSSVHSEQVFALRLQD--KKLPPLLSEIWDV 459
           Q   R  F +++  L  LR++++ H++++  LR+QD      PL+ E++ +
Sbjct: 383 QPAHRFLFLKIMAMLTELRSINAQHTQRL--LRIQDIHPFATPLMQELFGI 431


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  170 bits (430), Expect = 3e-42
 Identities = 115/383 (30%), Positives = 184/383 (48%), Gaps = 60/383 (15%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C VCGD+A+G+H+N L+CEGCKGFFRR+V +       C   G+C++    RR C  CRL
Sbjct: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRHCPACRL 68

Query: 147 RKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSE 206
           +KC +AGMR+  +LS E +  ++ ++ Q++  Q+                          
Sbjct: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP------------------------- 103

Query: 207 AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQ 266
                      VQL+  QE +I+ L+ A  +     F    +  P      P       Q
Sbjct: 104 -----------VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP------PAHLFIHHQ 146

Query: 267 RF----------AHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLET 316
                        HF ++    V +++ F K +P F  L  EDQI+LLK + +EI  +  
Sbjct: 147 PLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVL 206

Query: 317 ARRYNHETECITFL-KDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIA 375
              +  +T+   FL     Y+ +D  R G QVEF+  +F F   +R+L L + EY LL A
Sbjct: 207 NTTFCLQTQ--NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAA 264

Query: 376 INIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKRPQDQLRFPRMLMKLVSLRTLSS 433
           + +FS DRP V +   ++ LQ+     L SY +   +RP+D+  + ++L  L  LR+++ 
Sbjct: 265 MALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 324

Query: 434 VHSEQVFALRLQDKKLPPLLSEI 456
            +  Q+  ++     + PLL EI
Sbjct: 325 AYGYQIQHIQGLSAMM-PLLQEI 346


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  165 bits (417), Expect = 9e-41
 Identities = 111/379 (29%), Positives = 180/379 (47%), Gaps = 39/379 (10%)

Query: 64  DPEE------EPERKRKKGPAP---KMLGH--------ELCRVCGDKASGFHYNVLSCEG 106
           DPEE      + +RKRK G       M G+        E C VCGDKA+G+HY  ++CEG
Sbjct: 13  DPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEG 72

Query: 107 CKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSE-EQI 165
           CKGFFRR++ +     Y+C+    C +D   R +CQ CR +KC   GM    VL + +++
Sbjct: 73  CKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRV 132

Query: 166 RKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQE 225
            K+K+ +Q ++  + +       Q    +          +EA    + +G   +      
Sbjct: 133 AKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWK------ 186

Query: 226 LMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDF 285
                         +R F     +   P+ + P       + F+ FT++   ++  +VDF
Sbjct: 187 -------------QRRKFLPD-DIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDF 232

Query: 286 AKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGL 345
           AK++P F +L  EDQI LLK   +EIM L  A RY+ E++ +T   +    ++     GL
Sbjct: 233 AKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGL 292

Query: 346 QVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLS 405
            V   + IFE  +++    LDD E ALL A+ + S DR  +    ++E  Q+ Y+ A   
Sbjct: 293 GV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEH 351

Query: 406 YTRIKRPQDQLRFPRMLMK 424
           Y   ++      +P++LMK
Sbjct: 352 YVNHRKHNIPHFWPKLLMK 370


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  164 bits (415), Expect = 2e-40
 Identities = 115/387 (29%), Positives = 184/387 (47%), Gaps = 64/387 (16%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C VCGD+A+G+H+N L+CEGCKGFFRR+V +       C   G+C++    RR C  CRL
Sbjct: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRHCPACRL 68

Query: 147 RKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSE 206
           +KC +AGMR+  +LS E +  ++ ++ Q++  Q+                          
Sbjct: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP------------------------- 103

Query: 207 AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQ 266
                      VQL+  QE +I+ L+ A  +     F    +  P      P       Q
Sbjct: 104 -----------VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP------PAHLFIHHQ 146

Query: 267 RF----------AHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLET 316
                        HF ++    V +++ F K +P F  L  EDQI+LLK + +EI  +  
Sbjct: 147 PLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVL 206

Query: 317 ARRYNHETECITFL-KDFTYSKDDFHR----AGLQVEFINPIFEFSRAMRRLGLDDAEYA 371
              +  +T+   FL     Y+ +D  R     G QVEF+  +F F   +R+L L + EY 
Sbjct: 207 NTTFCLQTQ--NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYV 264

Query: 372 LLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKRPQDQLRFPRMLMKLVSLR 429
           LL A+ +FS DRP V +   ++ LQ+     L SY +   +RP+D+  + ++L  L  LR
Sbjct: 265 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELR 324

Query: 430 TLSSVHSEQVFALRLQDKKLPPLLSEI 456
           +++  +  Q+  ++     + PLL EI
Sbjct: 325 SINEAYGYQIQHIQGLSAMM-PLLQEI 350


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  160 bits (406), Expect = 2e-39
 Identities = 123/459 (26%), Positives = 193/459 (42%), Gaps = 68/459 (14%)

Query: 4   PTTSSLDTPLPGNG----PPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTD 59
           P   S    L G+G    PP P  P  SP          PG P P  PG     S+   +
Sbjct: 104 PLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQIN 163

Query: 60  WVI--------PDPEEEPERKRKKG------PAPKMLGHELCRVCGDKASGFHYNVLSCE 105
             +        P  + +P     +G      P     G  LC +CGD++SG HY V SCE
Sbjct: 164 STVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCE 223

Query: 106 GCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQI 165
           GCKGFF+R++ +     Y+CR    C +D   R +CQ CR +KC   GM+ + V  E Q 
Sbjct: 224 GCKGFFKRTIRKD--LTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQR 281

Query: 166 RKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQE 225
            K K                                         G GEG G    A +E
Sbjct: 282 GKDK----------------------------------------DGDGEGAG---GAPEE 298

Query: 226 LMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDF 285
           + + +++ A+L   ++S  DQ    P   G    S +          +  + +   +V++
Sbjct: 299 MPVDRILEAELAVEQKS--DQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFT---LVEW 353

Query: 286 AKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGL 345
           AK++P F  L  +DQ+ LL+A   E+++   + R     + I         ++  H AG+
Sbjct: 354 AKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGV 413

Query: 346 QVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLS 405
              F   + E    MR + +D  E   L AI +F+ D   +  P  VE L++    +L +
Sbjct: 414 GAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLET 473

Query: 406 YTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRL 444
           Y + K P+ Q RF ++L++L +LR++     E +F  +L
Sbjct: 474 YCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKL 512


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  158 bits (400), Expect = 9e-39
 Identities = 115/392 (29%), Positives = 184/392 (46%), Gaps = 69/392 (17%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C VCGD+A+G+H+N L+CEGCKGFFRR+V +       C   G+C++    RR C  CRL
Sbjct: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRHCPACRL 68

Query: 147 RKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSE 206
           +KC +AGMR+  +LS E +  ++ ++ Q++  Q+                          
Sbjct: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP------------------------- 103

Query: 207 AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQ 266
                      VQL+  QE +I+ L+ A  +     F    +  P      P       Q
Sbjct: 104 -----------VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP------PAHLFIHHQ 146

Query: 267 RF----------AHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLET 316
                        HF ++    V +++ F K +P F  L  EDQI+LLK + +EI  +  
Sbjct: 147 PLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVL 206

Query: 317 ARRYNHETECITFL-KDFTYSKDDFHR----AGLQVEFINPIFEFSRAMRRLGLDDAEYA 371
              +  +T+   FL     Y+ +D  R     G QVEF+  +F F   +R+L L + EY 
Sbjct: 207 NTTFCLQTQ--NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYV 264

Query: 372 LLIAINIFS-----ADRPNVQEPGRVEALQQPYVEALLSYTR--IKRPQDQLRFPRMLMK 424
           LL A+ +FS      DRP V +   ++ LQ+     L SY +   +RP+D+  + ++L  
Sbjct: 265 LLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGL 324

Query: 425 LVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 456
           L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 325 LAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 355


>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
          Length = 523

 Score =  154 bits (390), Expect = 1e-37
 Identities = 129/519 (24%), Positives = 228/519 (43%), Gaps = 106/519 (20%)

Query: 36  EPWPGGPDPDV--PGTDEASSACSTDWVIPDPEEEPERKRKKGPAP-------------- 79
           E  P  PDP    PG+  A +A  +      P  +   ++ + PAP              
Sbjct: 2   ESAPAAPDPAASEPGSSGADAAAGSR---ETPLNQESARKSEPPAPVRRQSYSSTSRGIS 58

Query: 80  -------KMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQ 132
                    +    C++CGDK+SG HY V++CEGCKGFFRRS        Y+C     C 
Sbjct: 59  VTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAT--YSCPRQKNCL 116

Query: 133 MDAFMRRKCQQCRLRKCKEAGMREQCV----LSEEQ-------IRKKKIRKQQQQESQSQ 181
           +D   R +CQ CRL+KC   GM    V    +S++Q       ++K ++++QQ+   Q  
Sbjct: 117 IDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQP 176

Query: 182 SQSPVGPQGSSSSASG------------PGASPGGSEAGS---------QGSGEGEGVQL 220
            ++       + SA+G             G +P GS+A S         Q S +  G+ +
Sbjct: 177 GEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDI 236

Query: 221 T---------------------------------AAQELMIQQLVAAQLQCNKRSFSDQP 247
                                             A  E + Q +  + L+  +    +  
Sbjct: 237 NGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQ 296

Query: 248 KVTPWPLGADPQSRDARQQRFAHFTELAIISVQE----IVDFAKQVPGFLQLGREDQIAL 303
           ++T W      +  + + ++     +L  I + E    +V+FAK++ GF++L + DQI L
Sbjct: 297 QIT-WQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 355

Query: 304 LKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRL 363
           LKA ++E++ +   R ++ +   + F  D  Y+  D  ++    +FI+ +FEF +++  +
Sbjct: 356 LKAGSLEVVFIRMCRAFDSQNNTVYF--DGKYASPDVFKSLGCEDFISFVFEFGKSLCSM 413

Query: 364 GLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLM 423
            L + E AL  A  + SADR  +QE  ++E LQQ  ++  L +   K  ++     +++ 
Sbjct: 414 HLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQK-IQLALQHVLQKNHREDGILTKLIC 472

Query: 424 KLVSLRTLSSVHSEQVFALR-----LQDKKLPPLLSEIW 457
           K+ +LR L   H+E++ A +     +     PPL  E++
Sbjct: 473 KVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 511


>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
          Length = 468

 Score =  154 bits (389), Expect = 2e-37
 Identities = 116/445 (26%), Positives = 207/445 (46%), Gaps = 80/445 (17%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C++CGDK+SG HY V++CEGCKGFFRRS        Y+C     C +D   R +CQ CRL
Sbjct: 18  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAT--YSCPRQKNCLIDRTSRNRCQHCRL 75

Query: 147 RKCKEAGMREQCV----LSEEQ-------IRKKKIRKQQQQESQSQSQSPVGPQGSSSSA 195
           +KC   GM    V    +S++Q       ++K ++++QQ+   Q   ++       + SA
Sbjct: 76  QKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISA 135

Query: 196 SG------------PGASPGGSEAGS---------QGSGEGEGVQLT------------- 221
           +G             G +P GS+A S         Q S +  G+ +              
Sbjct: 136 NGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPA 195

Query: 222 --------------------AAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSR 261
                               A  E + Q +  + L+  +    +  ++T W      +  
Sbjct: 196 SGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQIT-WQTFLQEEIE 254

Query: 262 DARQQRFAHFTELAIISVQE----IVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETA 317
           + + ++     +L  I + E    +V+FAK++ GF++L + DQI LLKA ++E++ +   
Sbjct: 255 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 314

Query: 318 RRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAIN 377
           R ++ +   + F  D  Y+  D  ++    +FI+ +FEF +++  + L + E AL  A  
Sbjct: 315 RAFDSQNNTVYF--DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFV 372

Query: 378 IFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSE 437
           + SADR  +QE  ++E LQQ  ++  L +   K  ++     +++ K+ +LR L   H+E
Sbjct: 373 LMSADRSWLQEKVKIEKLQQK-IQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTE 431

Query: 438 QVFALR-----LQDKKLPPLLSEIW 457
           ++ A +     +     PPL  E++
Sbjct: 432 KLMAFKAIYPDIVRLHFPPLYKELF 456


>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
          Length = 548

 Score =  154 bits (389), Expect = 2e-37
 Identities = 116/445 (26%), Positives = 207/445 (46%), Gaps = 80/445 (17%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C++CGDK+SG HY V++CEGCKGFFRRS        Y+C     C +D   R +CQ CRL
Sbjct: 98  CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAT--YSCPRQKNCLIDRTSRNRCQHCRL 155

Query: 147 RKCKEAGMREQCV----LSEEQ-------IRKKKIRKQQQQESQSQSQSPVGPQGSSSSA 195
           +KC   GM    V    +S++Q       ++K ++++QQ+   Q   ++       + SA
Sbjct: 156 QKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISA 215

Query: 196 SG------------PGASPGGSEAGS---------QGSGEGEGVQLT------------- 221
           +G             G +P GS+A S         Q S +  G+ +              
Sbjct: 216 NGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPA 275

Query: 222 --------------------AAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSR 261
                               A  E + Q +  + L+  +    +  ++T W      +  
Sbjct: 276 SGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQIT-WQTFLQEEIE 334

Query: 262 DARQQRFAHFTELAIISVQE----IVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETA 317
           + + ++     +L  I + E    +V+FAK++ GF++L + DQI LLKA ++E++ +   
Sbjct: 335 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 394

Query: 318 RRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAIN 377
           R ++ +   + F  D  Y+  D  ++    +FI+ +FEF +++  + L + E AL  A  
Sbjct: 395 RAFDSQNNTVYF--DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFV 452

Query: 378 IFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSE 437
           + SADR  +QE  ++E LQQ  ++  L +   K  ++     +++ K+ +LR L   H+E
Sbjct: 453 LMSADRSWLQEKVKIEKLQQK-IQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTE 511

Query: 438 QVFALR-----LQDKKLPPLLSEIW 457
           ++ A +     +     PPL  E++
Sbjct: 512 KLMAFKAIYPDIVRLHFPPLYKELF 536


>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
          Length = 556

 Score =  154 bits (389), Expect = 2e-37
 Identities = 116/445 (26%), Positives = 207/445 (46%), Gaps = 80/445 (17%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C++CGDK+SG HY V++CEGCKGFFRRS        Y+C     C +D   R +CQ CRL
Sbjct: 106 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAT--YSCPRQKNCLIDRTSRNRCQHCRL 163

Query: 147 RKCKEAGMREQCV----LSEEQ-------IRKKKIRKQQQQESQSQSQSPVGPQGSSSSA 195
           +KC   GM    V    +S++Q       ++K ++++QQ+   Q   ++       + SA
Sbjct: 164 QKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISA 223

Query: 196 SG------------PGASPGGSEAGS---------QGSGEGEGVQLT------------- 221
           +G             G +P GS+A S         Q S +  G+ +              
Sbjct: 224 NGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPA 283

Query: 222 --------------------AAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSR 261
                               A  E + Q +  + L+  +    +  ++T W      +  
Sbjct: 284 SGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQIT-WQTFLQEEIE 342

Query: 262 DARQQRFAHFTELAIISVQE----IVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETA 317
           + + ++     +L  I + E    +V+FAK++ GF++L + DQI LLKA ++E++ +   
Sbjct: 343 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 402

Query: 318 RRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAIN 377
           R ++ +   + F  D  Y+  D  ++    +FI+ +FEF +++  + L + E AL  A  
Sbjct: 403 RAFDSQNNTVYF--DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFV 460

Query: 378 IFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSE 437
           + SADR  +QE  ++E LQQ  ++  L +   K  ++     +++ K+ +LR L   H+E
Sbjct: 461 LMSADRSWLQEKVKIEKLQQK-IQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTE 519

Query: 438 QVFALR-----LQDKKLPPLLSEIW 457
           ++ A +     +     PPL  E++
Sbjct: 520 KLMAFKAIYPDIVRLHFPPLYKELF 544


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  152 bits (383), Expect = 8e-37
 Identities = 105/346 (30%), Positives = 163/346 (47%), Gaps = 63/346 (18%)

Query: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146
           C VCGD+A+G+H+N L+CEGCKGFFRR+V +       C   G+C++    RR C  CRL
Sbjct: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRHCPACRL 68

Query: 147 RKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSE 206
           +KC +AGMR+  +LS E +  ++ ++ Q++  Q+                          
Sbjct: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP------------------------- 103

Query: 207 AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQ 266
                      VQL+  QE +I+ L+ A  +     F    +  P      P       Q
Sbjct: 104 -----------VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP------PAHLFIHHQ 146

Query: 267 RF----------AHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLET 316
                        HF ++    V +++ F K +P F  L  EDQI+LLK + +EI  +  
Sbjct: 147 PLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVL 206

Query: 317 ARRYNHETECITFL-KDFTYSKDDFHR----AGLQVEFINPIFEFSRAMRRLGLDDAEYA 371
              +  +T+   FL     Y+ +D  R     G QVEF+  +F F   +R+L L + EY 
Sbjct: 207 NTTFCLQTQ--NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYV 264

Query: 372 LLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKRPQDQ 415
           LL A+ +FS DRP V +   ++ LQ+     L SY +   +RP+D+
Sbjct: 265 LLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,109,453
Number of Sequences: 37866
Number of extensions: 1260724
Number of successful extensions: 17460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 235
Number of HSP's successfully gapped in prelim test: 378
Number of HSP's that attempted gapping in prelim test: 13925
Number of HSP's gapped (non-prelim): 3176
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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