Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 77681565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|77681565 NG5 protein [Homo sapiens]
         (306 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|77681565 NG5 protein [Homo sapiens]                                651   0.0  
gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]          89   5e-18
gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]          89   5e-18
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]        74   2e-13
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    71   1e-12
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    70   2e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 70   3e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 68   9e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    67   2e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is...    67   2e-11
gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]       66   4e-11
gi|160707881 formin 2 [Homo sapiens]                                   65   6e-11
gi|116284392 mucin 2 precursor [Homo sapiens]                          65   8e-11
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    65   8e-11
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    65   8e-11
gi|11386183 WAS protein family, member 2 [Homo sapiens]                65   1e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 65   1e-10
gi|169178462 PREDICTED: similar to NG5 protein [Homo sapiens]          64   2e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    64   2e-10
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    64   2e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    64   2e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     63   4e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     63   4e-10
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r...    63   4e-10
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    62   6e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    62   8e-10
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          62   8e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          62   8e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          62   8e-10
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     61   1e-09

>gi|77681565 NG5 protein [Homo sapiens]
          Length = 306

 Score =  651 bits (1679), Expect = 0.0
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG
Sbjct: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60

Query: 61  AGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120
           AGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG
Sbjct: 61  AGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120

Query: 121 PLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVP 180
           PLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVP
Sbjct: 121 PLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVP 180

Query: 181 VYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGI 240
           VYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGI
Sbjct: 181 VYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGI 240

Query: 241 IAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHH 300
           IAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHH
Sbjct: 241 IAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHH 300

Query: 301 ENYWDP 306
           ENYWDP
Sbjct: 301 ENYWDP 306


>gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 288

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 91/288 (31%), Positives = 110/288 (38%), Gaps = 37/288 (12%)

Query: 23  PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLP 82
           P P A P   PPQ             H       P   AG     + +  +G  S AT P
Sbjct: 19  PLPAAPPSRTPPQTLK----------HLPSGEPGPPFPAGMPGGGSGSDTKGGGSPAT-P 67

Query: 83  RPPHHAPPGPAAGAPP--PGCATLPRMPPDPY-LQETRFEGPLPPPPPAAAA-------- 131
             P  +P  PAA   P  P    LP++P  P  L E    G   P   AAA         
Sbjct: 68  EDPR-SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFV 126

Query: 132 --PPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVY---PVGT 186
             PPP AP     AP    P     V   P    + P  P QL P     P     P G 
Sbjct: 127 GEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPP-PAQLYPAAPTPPALFSPPAGA 185

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKA 246
            +      G        P    PG A +E R  P DYM  +VL T+ C   TG+IAI  +
Sbjct: 186 AFPFPVYNG--------PMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYS 237

Query: 247 VQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVII 294
            + R AL RGD+  AE ASR+AR+    SL  G+       I  VV +
Sbjct: 238 HEARAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVAL 285



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 28/109 (25%)

Query: 17  PPPYNAPQPPAEPPAPPP--------QAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
           PPPY  P P A P   PP        Q APS              A  P       A+  
Sbjct: 129 PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS--------------ALFPPPAQLYPAAPT 174

Query: 69  ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMP-PDPYLQET 116
             A   P + A  P P ++   GP AG P P  AT+   P P  Y+ E+
Sbjct: 175 PPALFSPPAGAAFPFPVYN---GPMAGVPGP--ATVEHRPLPKDYMMES 218


>gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 288

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 91/288 (31%), Positives = 110/288 (38%), Gaps = 37/288 (12%)

Query: 23  PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLP 82
           P P A P   PPQ             H       P   AG     + +  +G  S AT P
Sbjct: 19  PLPAAPPSRTPPQTLK----------HLPSGEPGPPFPAGMPGGGSGSDTKGGGSPAT-P 67

Query: 83  RPPHHAPPGPAAGAPP--PGCATLPRMPPDPY-LQETRFEGPLPPPPPAAAA-------- 131
             P  +P  PAA   P  P    LP++P  P  L E    G   P   AAA         
Sbjct: 68  EDPR-SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFV 126

Query: 132 --PPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVY---PVGT 186
             PPP AP     AP    P     V   P    + P  P QL P     P     P G 
Sbjct: 127 GEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPP-PAQLYPAAPTPPALFSPPAGA 185

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKA 246
            +      G        P    PG A +E R  P DYM  +VL T+ C   TG+IAI  +
Sbjct: 186 AFPFPVYNG--------PMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYS 237

Query: 247 VQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVII 294
            + R AL RGD+  AE ASR+AR+    SL  G+       I  VV +
Sbjct: 238 HEARAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVAL 285



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 28/109 (25%)

Query: 17  PPPYNAPQPPAEPPAPPP--------QAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
           PPPY  P P A P   PP        Q APS              A  P       A+  
Sbjct: 129 PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS--------------ALFPPPAQLYPAAPT 174

Query: 69  ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMP-PDPYLQET 116
             A   P + A  P P ++   GP AG P P  AT+   P P  Y+ E+
Sbjct: 175 PPALFSPPAGAAFPFPVYN---GPMAGVPGP--ATVEHRPLPKDYMMES 218


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 72/231 (31%), Positives = 89/231 (38%), Gaps = 33/231 (14%)

Query: 19   PYNAPQPPAEPPAPPPQAAPSSHHHHHHHYH---QSGTATLPRLGAGGLASSAATAQRGP 75
            P+  P PP    +    +A S+HHHHHHH+H     G   LP  G   L +  A   +GP
Sbjct: 1217 PFQMPPPPTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPD-GQSKLQALHAQYCQGP 1275

Query: 76   S---------SSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPP 126
                         +LP PP   PP P  G+ PP  A+ P + P  +       GP+P P 
Sbjct: 1276 GPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHA---HGPVPGPQ 1332

Query: 127  PAAAAPPPPAPAQTAQ-----APGFVVPTHAGTVGTLPLGGYVAPGYPLQLQ-PCTAYVP 180
                  P  AP + A      AP    P H  T   LPL        P   Q P      
Sbjct: 1333 HYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPT-SPLPLYSPAPQHPPAHKQGPKHFIFS 1391

Query: 181  VYPVGTPYAG--GTPGG--TGVTSTLPPPPQGPGLALLEPRR--PPHDYMP 225
             +P   P AG  G PG    G + + P  PQ P    L P    PPH   P
Sbjct: 1392 HHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSP----LSPHSPIPPHPSYP 1438



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 53/183 (28%), Positives = 58/183 (31%), Gaps = 51/183 (27%)

Query: 8    LPDSVPHTSPPPYNAPQPP-----AEPPAPPPQAAPSSHHHHH------HHYHQSGTATL 56
            LP   P   PPP   P  P       PPA  P   P  H H H       HY        
Sbjct: 1283 LPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRA 1342

Query: 57   PRLGAGGLASSAATAQRGPSSSATLPRP---------------------PHHAPPGPAAG 95
            PR GAGG    A    R P    T P P                      HH    PAAG
Sbjct: 1343 PRRGAGGHPQFAPHG-RHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAG 1401

Query: 96   A-------PPPGCATLPRMPPDPYLQETRFEGPLPP-------PPPAAAAPPPPAPAQTA 141
            A       PP G  + P  P  P    +    P+PP       PPP+   P  P P  + 
Sbjct: 1402 AAGGPGSRPPGGSYSHPHHPQSPLSPHS----PIPPHPSYPPLPPPSPHTPHSPLPPTSP 1457

Query: 142  QAP 144
              P
Sbjct: 1458 HGP 1460



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 58/218 (26%), Positives = 65/218 (29%), Gaps = 80/218 (36%)

Query: 13   PHTSPPPYNAPQPPAEPPAP--------------PPQAAP--SSHHHHH--------HHY 48
            P  +PPPY  PQ P+ PP P              PP +AP    H H H         HY
Sbjct: 1275 PGPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHY 1334

Query: 49   HQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRP---------------------PHH 87
                    PR GAGG    A    R P    T P P                      HH
Sbjct: 1335 TLGRPGRAPRRGAGGHPQFAPHG-RHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHH 1393

Query: 88   APPGPAAGAP----------------------------PPGCATLPRMPPDPYLQETRFE 119
                PAAGA                             PP  +  P  PP P+   +   
Sbjct: 1394 PQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHS--- 1450

Query: 120  GPLPPPPPAAA--APPPPAPAQTAQAPGFVVPTHAGTV 155
             PLPP  P     A  PP  A    A     P+   TV
Sbjct: 1451 -PLPPTSPHGPLHASGPPGTANPPSANPKAKPSRISTV 1487



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 42/149 (28%), Positives = 53/149 (35%), Gaps = 31/149 (20%)

Query: 9   PDSVPHTSPPPYNAPQ---PPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLP----RLGA 61
           P+ +P T PPP   P+   P   PP PPP  + +          + G   L     RL A
Sbjct: 529 PERLPSTEPPPQGRPEFWAPAPLPPVPPPVPSGTREDGSREEGTRRGPGCLECRDFRLRA 588

Query: 62  GGL------------ASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLP-RMP 108
             L               +  + RG      +      +P G      PPG A +P R  
Sbjct: 589 AHLPLLTIEPPSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPGRAPIPHRHY 648

Query: 109 PDPYLQETRFEGPLPPPPPAAAAPPPPAP 137
           P P       EGP P PP     P PPAP
Sbjct: 649 PAP-------EGPAPAPP----GPLPPAP 666


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 64/252 (25%), Positives = 86/252 (34%), Gaps = 59/252 (23%)

Query: 12   VPHTSPPPYNAPQPPA------------EPPAPPPQAAPSSHHHHH------HHYHQ--- 50
            +P +SP  ++ P PP               P PP    P  HHHHH      HH+H    
Sbjct: 962  LPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPP 1021

Query: 51   ---------SGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAP---- 97
                     S     PRL  G   S       GPS +   P P HH   G   G+     
Sbjct: 1022 HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPA 1081

Query: 98   ------PPGCATLPRMPP--------DPYLQETRFEG---------PLPPPPPAAAAPPP 134
                  PP  A+     P         P +++T+ EG         P P P   A+  PP
Sbjct: 1082 LRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP 1141

Query: 135  PAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPG 194
            PA A  ++     +PT      +    G  + G   + +P T   P    G    G +P 
Sbjct: 1142 PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPT--GGGGGGGSSPS 1199

Query: 195  GTGVTSTLPPPP 206
                 S +PP P
Sbjct: 1200 PAPAMSPVPPSP 1211



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 49/182 (26%), Positives = 64/182 (35%), Gaps = 48/182 (26%)

Query: 22   APQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATL----------PRLG-AGGLASSAAT 70
            APQPP  PP+P  +A P + HHH  H H      L            LG   GL S   +
Sbjct: 1373 APQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKS 1432

Query: 71   AQRGPSSS--ATLPRPPHHA-------------PPGPAAGAPPPGCATLPRMPP------ 109
                P ++  + L R P  A             PP P  G   P  +  P  P       
Sbjct: 1433 LPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHV 1492

Query: 110  ------DPYLQETRFEGP-------LPPPPPAAAAPPPPAPAQTAQAPG---FVVPTHAG 153
                   P    T   GP       +PPP P  + PP P   + ++  G    V+P  A 
Sbjct: 1493 RFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAP 1552

Query: 154  TV 155
            +V
Sbjct: 1553 SV 1554



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 34/119 (28%), Positives = 45/119 (37%), Gaps = 21/119 (17%)

Query: 18   PPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSS 77
            PP  +P  PA P  PP  AAPS          +  +  +P +     A S +++ R    
Sbjct: 1127 PPAPSPTSPASPQPPPAVAAPS----------EKNSIPIPTIIIK--APSTSSSGRSSQG 1174

Query: 78   SATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPA 136
            S+T   PP    P    G      +  P M P P         P P P P  A+P  PA
Sbjct: 1175 SSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP---------PSPSPVPTPASPSGPA 1224



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 66/272 (24%), Positives = 84/272 (30%), Gaps = 71/272 (26%)

Query: 1    MSSEKSGLPDSVP-------HTSPP--PYNAP---QPPAEPPAPPP-------QAAPSSH 41
            + S++  LP S P       H  PP  P   P   Q   EPPAP P        AAP   
Sbjct: 1426 LGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEP 1485

Query: 42   HHH--HHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHA----------- 88
                 H  + ++     P     G  S        PS   ++P  P              
Sbjct: 1486 ERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLL 1545

Query: 89   ---PPGPAAGA-----------PPP---------GCATLPRMPPDPYLQETRFEGPLPPP 125
               PP P+              PPP           + L   PP P         PLPP 
Sbjct: 1546 VLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPV 1605

Query: 126  PPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVG 185
            PP A A  PP    TA +    + ++   V TL  G   APG P            +P G
Sbjct: 1606 PPPAVAAAPPTLDSTASS----LTSYDSEVATLTQGASAAPGDP------------HPPG 1649

Query: 186  TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPR 217
             P               PPP    G+  ++ R
Sbjct: 1650 PPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSR 1681



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 51/199 (25%), Positives = 65/199 (32%), Gaps = 27/199 (13%)

Query: 51   SGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPG---------- 100
            +G A  P    G   ++   A +  S     P+PP   PP P   APPP           
Sbjct: 1343 TGKALDPASPLGLALAARERALKESSEGGGAPQPPPR-PPSPRYEAPPPTPHHHSPHAHH 1401

Query: 101  ---CATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGT 157
                      PPDP  +E  +   L     +  A PP A           +P  A  VG 
Sbjct: 1402 EPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHR----LPPTAPGVGP 1457

Query: 158  L--PLGGYVAPGYPLQLQPCTAYVPVYPVGTPY-----AGGTPGGTGVTSTLPPPPQGPG 210
            L   LG      +P   +P  +  P  P   P          P     +   PP   GPG
Sbjct: 1458 LLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPG 1517

Query: 211  LALLEPRR--PPHDYMPIA 227
            +    PRR  PP    P A
Sbjct: 1518 VPPPSPRRSVPPSPTSPRA 1536



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 50/177 (28%), Positives = 62/177 (35%), Gaps = 47/177 (26%)

Query: 75   PSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETR---------FEGPLPP- 124
            PSSS  L   P   P  P +G P P  A+ P     P   +TR           GPLPP 
Sbjct: 939  PSSSGRLTPSPRGGPFNPGSGGPLP--ASSPASFDGPSPPDTRVGSREKSLYHSGPLPPA 996

Query: 125  ------------PPPAA----AAPPPPAPAQTAQAPGFVVPTHAGTVGTLP-LGGYVAPG 167
                        PPP      A PP P   +T  +P    P  A  +G  P L G+   G
Sbjct: 997  HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLA--LGPQPSLRGWRGGG 1054

Query: 168  YPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPP------PPQGPGLALLEPRR 218
                        P     +P   G+ GG G +S  P       PP+    A+  P R
Sbjct: 1055 PS----------PTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPAR 1101



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 12/87 (13%)

Query: 60   GAGGLASSAATAQRGPSSSATL----PRPPHHAPPGPAAG-APPPGCATLPRMPPDPYLQ 114
            G GG  + +     G  SSA      PRP  H   G A   A P G A   R   +  L+
Sbjct: 1309 GYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAAR---ERALK 1365

Query: 115  ETRFEGPLPPPPPAAAAP----PPPAP 137
            E+   G  P PPP   +P    PPP P
Sbjct: 1366 ESSEGGGAPQPPPRPPSPRYEAPPPTP 1392



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 34/126 (26%), Positives = 46/126 (36%), Gaps = 26/126 (20%)

Query: 60  GAGGLASSAATAQRGPSSSATLPRPPHHAPPG---PAAGAPPPGCATLPRM-----PPDP 111
           G GGLAS      +G  ++ +   P H A P    P+   P PG     +         P
Sbjct: 840 GPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRP 899

Query: 112 YLQETRFE----------GPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLG 161
           YL     +            +PPPP  +   PP  P  T       VP+ +G +   P G
Sbjct: 900 YLAPPAMKFSRSLSVPGSEDIPPPPTTS---PPEPPYSTPP-----VPSSSGRLTPSPRG 951

Query: 162 GYVAPG 167
           G   PG
Sbjct: 952 GPFNPG 957



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 18/59 (30%), Positives = 21/59 (35%)

Query: 92   PAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPT 150
            P AG      A  P +PP P    +     L P       PPPP P   AQ     + T
Sbjct: 1807 PTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALAT 1865



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 55   TLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQ 114
            T+   GAG     A  A  GP ++     P    P  P    P P  ++LPR      L 
Sbjct: 1786 TVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPV--PLPTASSLPRK----LLP 1839

Query: 115  ETRFEGPLPPPPPAAAAPPPPAPAQTAQA 143
                 GP PPP P   A P  +   T +A
Sbjct: 1840 WEEGPGPPPPPLPGPLAQPQASALATVKA 1868



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 78  SATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFE----GPLPPPPPAAAAPP 133
           S  +P PP  +PP P    PP   ++  R+ P P  +   F     GPLP   PA+   P
Sbjct: 917 SEDIPPPPTTSPPEPPYSTPPVPSSS-GRLTPSP--RGGPFNPGSGGPLPASSPASFDGP 973

Query: 134 PP 135
            P
Sbjct: 974 SP 975


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 65/213 (30%), Positives = 73/213 (34%), Gaps = 40/213 (18%)

Query: 13  PHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           P   PPP+   Q P  P  PPPQ  P      H   HQ                     Q
Sbjct: 59  PIPPPPPHQQQQQPP-PQQPPPQQPPPHQPPPHPQPHQQ--------------------Q 97

Query: 73  RGPSSSATLPRPPHHAPPGPAAG---APPPGCATLPRMPPDPYLQETRFEGPLPPPPPAA 129
           + P       +P     PGPA G   APP   +  P  PP          GP P PPPA 
Sbjct: 98  QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157

Query: 130 AAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYA 189
            + PP AP  T  + G  VPT     G  P      PG      P          G P  
Sbjct: 158 TSAPPGAPPPTPPSSG--VPTTPPQAGGPPPPPAAVPG------PGPGPKQGPGPGGPKG 209

Query: 190 GGTPGGTGVTSTLPPPPQGPGLALLEPR-RPPH 221
           G  PGG       P P  GPGL+      +PPH
Sbjct: 210 GKMPGG-------PKPGGGPGLSTPGGHPKPPH 235



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 63/211 (29%), Positives = 75/211 (35%), Gaps = 33/211 (15%)

Query: 9   PDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
           P   P   PPP+  P    +PP PP  ++              G    P +G+   ASS+
Sbjct: 79  PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKP--------VVAQGPGPAPGVGSAPPASSS 130

Query: 69  ATAQRGPSSSATLPRPPHHAP-PGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPP 127
           A     P+S A     P   P P PA  + PPG    P  PP   +  T  +   PPPPP
Sbjct: 131 APPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP--PPTPPSSGVPTTPPQAGGPPPPP 188

Query: 128 AAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTP 187
           AA   P P P Q         P   G  G    GG    G P    P     P      P
Sbjct: 189 AAVPGPGPGPKQG--------PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP------P 234

Query: 188 YAGGTPGGTGVTSTLP--------PPPQGPG 210
           + GG     G     P        PPP GPG
Sbjct: 235 HRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 46/169 (27%), Positives = 57/169 (33%), Gaps = 36/169 (21%)

Query: 63  GLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPL 122
           G+  +      GP    + P+PP   PP       PP     P+ PP           P 
Sbjct: 37  GMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP--------HQPP 88

Query: 123 PPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVY 182
           P P P     PPP P  +++      P  A  VG+ P     AP                
Sbjct: 89  PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP---------------- 132

Query: 183 PVGTPYAGGTPG-GTGVTSTLPP-----PPQGPGLALLEPRRPPHDYMP 225
           P   P +G  PG G G T T PP     PP  P      P  PP   +P
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP------PPTPPSSGVP 175



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 34/126 (26%), Positives = 39/126 (30%), Gaps = 18/126 (14%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           ++S   G P   P +S  P   PQ     P PPP A P             G       G
Sbjct: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGG--PPPPPAAVPG-----------PGPGPKQGPG 203

Query: 61  AGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120
            GG           P     L  P  H  P    G  P G     R    PY Q+   +G
Sbjct: 204 PGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRG----GRQHHPPYHQQ-HHQG 258

Query: 121 PLPPPP 126
           P P  P
Sbjct: 259 PPPGGP 264



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 4/73 (5%)

Query: 17  PPPYNAP--QPPAEPPAPPPQAA--PSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           P P   P    P   P PP +    P     HH  YHQ      P  G GG +    +  
Sbjct: 216 PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDS 275

Query: 73  RGPSSSATLPRPP 85
            G  ++ +L R P
Sbjct: 276 EGFKANLSLLRRP 288


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 43/245 (17%)

Query: 7   GLPDSVPHTSPP-------------PYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGT 53
           G P S PH  P              P   P P  +PP PP    P    HH       G 
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH-------GP 444

Query: 54  ATLPR-LGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPY 112
             + + LG+  + S      +G       P      PP P +G PPP     P   P P 
Sbjct: 445 PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-----PPSGPLPP 499

Query: 113 LQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLP------LGGYVAP 166
            Q+ + + P PPPP ++ A   P P Q          T AGT G++P           +P
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPLPWQQNTT---TTTTSAGT-GSIPPWQQQQAAAAASP 555

Query: 167 GYPLQLQPCTAYVPVYP-VGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
           G P Q+Q     VP+ P V  P   G P         PPPP   G+    P  PP    P
Sbjct: 556 GAP-QMQGNPTMVPLPPGVQPPLPPGAP-----PPPPPPPPGSAGMMYAPPPPPPPPMDP 609

Query: 226 IAVLT 230
              +T
Sbjct: 610 SNFVT 614



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 48/169 (28%), Positives = 58/169 (34%), Gaps = 39/169 (23%)

Query: 17  PPPYNAPQPP----AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLA-----SS 67
           PPP + P PP     + P PPP  + S        + Q+ T T    G G +       +
Sbjct: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549

Query: 68  AATAQRGP----SSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLP 123
           AA A  G      +   +P PP   PP P    PPP                       P
Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP-----------------------P 586

Query: 124 PPPPAAAA---PPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYP 169
           PPPP +A     PPP P        FV     G  G  P G   AP  P
Sbjct: 587 PPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPP 635



 Score = 35.0 bits (79), Expect = 0.083
 Identities = 46/175 (26%), Positives = 57/175 (32%), Gaps = 52/175 (29%)

Query: 76  SSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYL----QETR-------------- 117
           S  AT P      P  PA   PPP   +  +  P P++     E+R              
Sbjct: 333 SGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP-PWMNSGPSESRPYHGMHGGGPGGPG 391

Query: 118 -----FEGPLPP----------------PPPAAAAPPPPAPAQTAQAPGFVVPTHAGT-V 155
                F  PLP                 PPP    PPPP   Q    PG   P      +
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYL 451

Query: 156 GTLPLGGYVAPGYPLQLQPCTAYVPVYPVG-TPYAGGTPGGTGVTSTLPPPPQGP 209
           G+ P+G  V      +L      +P  P+G  P     P G       PPPP GP
Sbjct: 452 GSTPVGSGV-----YRLHQGKGMMPPPPMGMMPPPPPPPSGQP-----PPPPSGP 496


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 66/231 (28%), Positives = 85/231 (36%), Gaps = 42/231 (18%)

Query: 7   GLPDSVPHTSPP-------------PYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGT 53
           G P S PH  P              P   P P  +PP PP    P    HH       G 
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH-------GP 444

Query: 54  ATLPR-LGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPY 112
             + + LG+  + S      +G       P      PP P +G PPP     P   P P 
Sbjct: 445 PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-----PPSGPLPP 499

Query: 113 LQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLP------LGGYVAP 166
            Q+ + + P PPPP ++ A   P P Q          T AGT G++P           +P
Sbjct: 500 WQQQQQQPPPPPPPSSSMASSTPLPWQQNTT---TTTTSAGT-GSIPPWQQQQAAAAASP 555

Query: 167 GYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPR 217
           G P Q+Q     VP+ P   P     P   G     PPPP G    ++ PR
Sbjct: 556 GAP-QMQGNPTMVPLPPGVQP-----PLPPGAPPPPPPPPPGSAGMMIPPR 600



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 33/149 (22%)

Query: 6   SGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLA 65
           SG P   P    PP+   Q    PP PP  +  SS       + Q+ T T    G G + 
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASS---TPLPWQQNTTTTTTSAGTGSI- 541

Query: 66  SSAATAQRGPSSSATLPRPPHHAPPGPAAGAP-PPGCATLPRMPPDPYLQETRFEGPLPP 124
                             PP       AA +P  P     P M P P        G  PP
Sbjct: 542 ------------------PPWQQQQAAAAASPGAPQMQGNPTMVPLP-------PGVQPP 576

Query: 125 PPPAAAAPPPPAPAQTAQAPGFVVPTHAG 153
            PP A  PPPP P  +A   G ++P   G
Sbjct: 577 LPPGAPPPPPPPPPGSA---GMMIPPRGG 602



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 45/162 (27%), Positives = 58/162 (35%), Gaps = 27/162 (16%)

Query: 17  PPPYNAPQPP----AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           PPP + P PP     + P PPP  + S        + Q+ T T    G G    S    Q
Sbjct: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG----SIPPWQ 545

Query: 73  RGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAP 132
           +  +++A  P  P      P     PPG    P +PP           P PPPP     P
Sbjct: 546 QQQAAAAASPGAPQ-MQGNPTMVPLPPGVQ--PPLPPG---------APPPPPP-----P 588

Query: 133 PPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQP 174
           PP +        G   P+H       PL     PG   Q +P
Sbjct: 589 PPGSAGMMIPPRGGDGPSHESEDFPRPL--VTLPGRQPQQRP 628



 Score = 35.0 bits (79), Expect = 0.083
 Identities = 46/175 (26%), Positives = 57/175 (32%), Gaps = 52/175 (29%)

Query: 76  SSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYL----QETR-------------- 117
           S  AT P      P  PA   PPP   +  +  P P++     E+R              
Sbjct: 333 SGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP-PWMNSGPSESRPYHGMHGGGPGGPG 391

Query: 118 -----FEGPLPP----------------PPPAAAAPPPPAPAQTAQAPGFVVPTHAGT-V 155
                F  PLP                 PPP    PPPP   Q    PG   P      +
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYL 451

Query: 156 GTLPLGGYVAPGYPLQLQPCTAYVPVYPVG-TPYAGGTPGGTGVTSTLPPPPQGP 209
           G+ P+G  V      +L      +P  P+G  P     P G       PPPP GP
Sbjct: 452 GSTPVGSGV-----YRLHQGKGMMPPPPMGMMPPPPPPPSGQP-----PPPPSGP 496


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 70/245 (28%), Positives = 90/245 (36%), Gaps = 37/245 (15%)

Query: 9   PDSVPHTSPPPYNAP-QPPAEPPAPP-PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLAS 66
           P + P  + PP  AP  PPA PP  P    +P + +    H  Q+  +  P        S
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678

Query: 67  SAATAQRGPSSSA------TLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120
             A+    PS++       +L  PP   PP P A  P    AT P   P P         
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738

Query: 121 PLPPPPPA---AAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLG--------GYVAPGYP 169
           P PP  P    +A PPP  P   A  P  V P+   ++   PL             P  P
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP--P 796

Query: 170 LQLQPC-------------TAYVPVYPVGTPYAGGTPGGTGVTSTLPP-PPQGPGLALLE 215
           LQ  P              +A +P+ P+ TP     P        +PP PP  P   L  
Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQA 854

Query: 216 PRRPP 220
           PRRPP
Sbjct: 855 PRRPP 859



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 67/245 (27%), Positives = 85/245 (34%), Gaps = 50/245 (20%)

Query: 4   EKSGLPDSVPHTSPPPYNAPQPPAEPPAP---PPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           + +  P + PH   PP  AP P   PP+P   PP   PSS             AT P   
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS------------IATPPPQA 594

Query: 61  AGGLASS----------AATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCAT------- 103
              LAS           +  A   P +   L  PP  APP P A  P    AT       
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654

Query: 104 --------LPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTV 155
                    P  PP     +  F  P  PP   +A PP  AP   A  P  V P+   + 
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714

Query: 156 GTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLE 215
              P+     P  P Q  P  A  P+    +P     P    ++ +  PPP+ P L    
Sbjct: 715 ---PMSPSATP--PPQAPPPLAAPPLQVPPSP-----PASPPMSPSATPPPRVPPLLAAP 764

Query: 216 PRRPP 220
           P + P
Sbjct: 765 PLQVP 769



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 74/241 (30%), Positives = 90/241 (37%), Gaps = 40/241 (16%)

Query: 2   SSEKSGLPDSVPHTS-PPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           S   S  P S P  S P     P+ PA P  P P+   +          +    T PR  
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL---------RPPQVTPPRKD 291

Query: 61  AG---GLASSAATAQRGPSSSATLPRPP--HHAPPGPAAGAPPPGCAT-LPRMPPDPYLQ 114
           A    G  SS+  A   PS +   P PP  + A P PA   P P  AT LP  PP P   
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351

Query: 115 ETRFEGPLPPPPPAAAAPP----PP--APAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGY 168
            +    P PP  P + APP    PP  AP      P   VP H+ T  +L      AP  
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP-HSLTSPSLQ-----APPS 405

Query: 169 PLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRP---PHDYMP 225
           PL L    A   +         G+P      S L   P+    +L  P RP   P D  P
Sbjct: 406 PLALSSLQATTSL---------GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456

Query: 226 I 226
           +
Sbjct: 457 L 457



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 59/215 (27%), Positives = 73/215 (33%), Gaps = 23/215 (10%)

Query: 19  PYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAG-------GLASSA--- 68
           P  AP     PP   P+ + SS   H            P  G G        L+SSA   
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 69  -ATAQRGPSSSATLPRPPHHAPPGP-AAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPP 126
            + A+ GPS+  T   P H + P P    A  P   T PR    P L          P P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 127 PAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGT 186
               A P P P   A      +P        LPL    +P  P  LQ   +     P  T
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP-PSPSAPPSLQTLPS-----PPAT 363

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPH 221
           P +   P     + T PP    P L  + P + PH
Sbjct: 364 PPSQAPP-----SMTTPPMQAPPSLQTIPPIQVPH 393



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 77/268 (28%), Positives = 90/268 (33%), Gaps = 70/268 (26%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNA-PQPPAEPP----------------APPPQAAPSSHHH 43
           MS   +  P + P  + PP    P PPA PP                APP Q  PS    
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP--- 772

Query: 44  HHHHYHQSGTATLPRLGAGGLASSAATAQRGP----------SSSATLPRPPHHAPP--- 90
                  S  A  P      LA+    A   P          S SA+LP  P   PP   
Sbjct: 773 -PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831

Query: 91  GPAAGAP-------PPGCATL--PRMPPDPYLQETRFEGP------LPPPPPAAAAPPPP 135
            P   AP       PP   TL  PR PP P   +T   GP       P PPP    PP  
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPPP----PPSR 886

Query: 136 APAQTAQAPGFVVPTHAGTVGTLPLGGY---------VAPGYPLQLQPCTAYVPVYPVGT 186
           +P+ T   P     + + T     L GY          +P    +L  C           
Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946

Query: 187 PYA-GGTPGGTGVTSTLP-PPPQGPGLA 212
           P A  G PG     + LP PP  GPG A
Sbjct: 947 PLAFRGAPG-----APLPWPPATGPGSA 969



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 56/221 (25%), Positives = 77/221 (34%), Gaps = 30/221 (13%)

Query: 8   LPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASS 67
           +P     +S  P +   PPA    PP +                    LP L    L ++
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLE-------------------NLPSLAPPPLQTA 549

Query: 68  AATAQRGPSSSATLPRP-PHHAPPGPAAGAPPPGCATLPRMPPD--PYLQETRFEGPLPP 124
           +A        +   P P P  APP P    PP   +++   PP   P L     +G   P
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609

Query: 125 PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQ-----LQPCTAYV 179
           P    A PPP AP   A  P    P+   +    PL    +P  P       LQ   +  
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPP 668

Query: 180 PVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
           P  PV  P++   P    V+ +  PP Q P      P + P
Sbjct: 669 PSPPVQAPFS--PPASPPVSPSATPPSQAPPSLAAPPLQVP 707



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 64/240 (26%), Positives = 82/240 (34%), Gaps = 50/240 (20%)

Query: 11  SVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAAT 70
           S P ++PP     Q P   PA PP     S          S   T+  L A  L+S A+ 
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS----PLSSPLTIHPLQA--LSSLASH 498

Query: 71  AQRGPSSSATLP---RPPHHAPPG---PAAGAPPPGCATLPRMPP-----------DPYL 113
           + + P SS  +P        APP    P A    P    LP + P            P+L
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558

Query: 114 QETRFEGPLP--PPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQ 171
           +      P P   PP     PPP  P+  A  P    P     + + PL G  +P     
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP----PQAPPALASPPLQGLPSP----- 609

Query: 172 LQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPP---PPQGPGLALLEPRRPPHDYMPIAV 228
                   P+ P+ TP     P        LPP   PP  P    L P   P    P A+
Sbjct: 610 --------PLSPLATPPPQAPP-----XLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 37/138 (26%), Positives = 46/138 (33%), Gaps = 28/138 (20%)

Query: 5   KSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGL 64
           K+G     P    P    P+PP  P  PPP                   A L  LGA G 
Sbjct: 9   KAGAAARTPAARAPGLLTPRPPGSPRPPPPVT----------------PAALRVLGAAGA 52

Query: 65  ASSAATAQR-GPSSSATLPRPPHHAPPGPAAG-------APPPGCATLPRMPPDPYLQET 116
                 A+R G    AT+P     A P  +AG       + PP      R PP     + 
Sbjct: 53  VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP----AKN 108

Query: 117 RFEGPLPPPPPAAAAPPP 134
              GP+  P  A+    P
Sbjct: 109 TSPGPVSSPGRASGTTRP 126



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 31/109 (28%), Positives = 36/109 (33%), Gaps = 21/109 (19%)

Query: 117 RFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL----GGYVAPGYPLQL 172
           R  G L P PP +  PPPP      +  G      AG VG  PL    GG      P   
Sbjct: 20  RAPGLLTPRPPGSPRPPPPVTPAALRVLG-----AAGAVGRKPLAERAGGIGGATIP--- 71

Query: 173 QPCTAYVPVYPVGT---------PYAGGTPGGTGVTSTLPPPPQGPGLA 212
           +      P    GT         P +G         +T P P   PG A
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 66/242 (27%), Positives = 80/242 (33%), Gaps = 34/242 (14%)

Query: 11  SVPHTSPPPYNAPQPPAEPPAPPP---QAAPSSHH------------HHHHHYHQSGTAT 55
           S P   PPP   P PP  PP PPP   Q+APS+                 +    SG   
Sbjct: 625 SPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684

Query: 56  LPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAG----APPPGCATLPRM--PP 109
            P       + S       P +    P PP   PP P +      P P   +LP+   PP
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP 744

Query: 110 DP-----YLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYV 164
            P         T+   P PPPPP   AP PP   Q    P   +P    T    P+    
Sbjct: 745 PPLKIHQVQHITQVAPPTPPPPPPIPAPLPP---QAPPKPLVTIPAPTSTKTVAPVVTQA 801

Query: 165 APGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYM 224
           AP  P    P     P +P     A   P          PPP  P       + PP    
Sbjct: 802 APPTPTPPVPPAKKQPAFP-----ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856

Query: 225 PI 226
           P+
Sbjct: 857 PV 858



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 60/218 (27%), Positives = 74/218 (33%), Gaps = 45/218 (20%)

Query: 23  PQPPAEPPAP---PPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSA 79
           P PP  PP P   PPQA P                T+P   +    +   T    P+   
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKP------------LVTIPAPTSTKTVAPVVTQAAPPTP-- 806

Query: 80  TLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPP-----------A 128
           T P PP    P   A   PP   T P   P P L + +     PPP P           A
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866

Query: 129 AAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVP-VYPVGTP 187
           +  PPPP P      P   VP +            VAP  P  ++    + P   PV +P
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPAN------------VAPQSPPAVKAKPKWQPSSIPVPSP 914

Query: 188 YAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
                P  + +    PPPP  P  A   P  PP    P
Sbjct: 915 DFPPPPPESSL--VFPPPPPSPVPA--PPPPPPPTASP 948



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 9/131 (6%)

Query: 90  PGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVP 149
           P P    P       P +PP P         P PPPPP    PPPP P+Q+A + G   P
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPP--------PPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662

Query: 150 THAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGP 209
                  T+      +       +P T  V       P     P G       PPPP  P
Sbjct: 663 MFV-KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTP 721

Query: 210 GLALLEPRRPP 220
           G A+ + +  P
Sbjct: 722 GSAMAQLKPAP 732



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 41/147 (27%), Positives = 47/147 (31%), Gaps = 30/147 (20%)

Query: 17  PPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPS 76
           P  Y  P PP  P   PP   P           QS  A  P      L+   +  ++  S
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQ---------QSFCAKPP---PSPLSPVPSVVKQIAS 867

Query: 77  SSATLPRPP----HHAPPGPAAGAP--PPGCATLPR------------MPPDPYLQETRF 118
                P PP        P PA  AP  PP     P+             PP P      F
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927

Query: 119 EGPLPPPPPAAAAPPPPAPAQTAQAPG 145
             P P P PA   PPPP  + T    G
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSG 954



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 54/210 (25%), Positives = 77/210 (36%), Gaps = 41/210 (19%)

Query: 4    EKSGLPDSVPHTSPPPYNA-----PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPR 58
            + S +P   P   PPP  +     P PP+  PAPPP   P++            + T  +
Sbjct: 905  QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA------------SPTPDK 952

Query: 59   LGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRF 118
             G+ G  +S  ++   P      P P  ++    ++GA  P     P+ P    L  ++F
Sbjct: 953  SGSPGKKTSKTSS---PGGKKPPPTPQRNSSIKSSSGAEHPE----PKRPSVDSL-VSKF 1004

Query: 119  EGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAY 178
              P     P+    PPPA      AP           G L L G   PG  LQ    +A 
Sbjct: 1005 TPPAESGSPSKETLPPPA------AP--------PKPGKLNLSGVNLPGV-LQQGCVSAK 1049

Query: 179  VPVYP-VGTPYAGGTPGGTGVTSTLPPPPQ 207
             PV    G       P     +   PPPP+
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPE 1079



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 56/229 (24%), Positives = 73/229 (31%), Gaps = 33/229 (14%)

Query: 17   PPPYNAPQPPAEPPAP-PPQAAPSSHHHHHHHYHQSGTATLPRLGAGGL-ASSAATAQRG 74
            PPP   P   ++P  P P   AP S                P+     +   S       
Sbjct: 870  PPPPTPPAMESQPLKPVPANVAPQS---------PPAVKAKPKWQPSSIPVPSPDFPPPP 920

Query: 75   PSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGP---LPPPPP---- 127
            P SS   P PP    P P    PPP  +  P     P  + ++   P    PPP P    
Sbjct: 921  PESSLVFPPPPPSPVPAPPP-PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979

Query: 128  ------AAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVP- 180
                   A  P P  P+  +    F  P  +G+     L    AP  P +L      +P 
Sbjct: 980  SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPG 1039

Query: 181  VYPVGTPYA-GGTPGGTGVTSTL--PPPPQGPGLALLEPRRPPHDYMPI 226
            V   G   A      G G  S +  P PP         P  PP   +P+
Sbjct: 1040 VLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF----PPPPPETELPL 1084



 Score = 32.3 bits (72), Expect = 0.54
 Identities = 41/161 (25%), Positives = 47/161 (29%), Gaps = 40/161 (24%)

Query: 13   PHTSPPPYNAPQPPAEP---PAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAA 69
            P   P P  AP PP  P   P P    +P                  P+  +   +SS A
Sbjct: 928  PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987

Query: 70   -------------------TAQRGPSSSATLPRPPHHAPPGPA---------AGAPPPGC 101
                                A+ G  S  TLP P   APP P           G    GC
Sbjct: 988  EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPA--APPKPGKLNLSGVNLPGVLQQGC 1045

Query: 102  --ATLPRMPPDPYLQETRFEGP-----LPPPPPAAAAPPPP 135
              A  P +          F  P      PPPPP    P PP
Sbjct: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPP 1086


>gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]
          Length = 340

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 77/311 (24%), Positives = 115/311 (36%), Gaps = 24/311 (7%)

Query: 3   SEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGT-----ATLP 57
           SE    P  V    P    APQP     A P  + P +          +G      AT  
Sbjct: 28  SEAETGPPQVLAGVPDQPEAPQPGPNTTAAPVDSGPKAGLAPETTETPAGASETAQATDL 87

Query: 58  RLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAA---GAPPPGCATLPRMPPDPYLQ 114
            L  GG + +  + +     + + P     A     +    A PP  A  P   PDP   
Sbjct: 88  SLSPGGESKANCSPEDPCQETVSKPEVSKEATADQGSRLESAAPPEPAPEPAPQPDPRPD 147

Query: 115 ETRFEGP-LPPPPPAAAAPPPPAPAQTA---QAPGFVVPTHAGTVGTLPLGGYVAPGYPL 170
                 P L P  P    P P   +++    Q  G VVP  AG     P     +P  P 
Sbjct: 148 SQPTPKPALQPELPTQEDPTPEILSESVGEKQENGAVVPLQAGDGEEGPAPEPHSP--PS 205

Query: 171 QLQPCTAYVPVYPVGTPYA--------GGTPGGTGVTSTLPPPPQ--GPGLALLEPRRPP 220
           +  P     P   +              G PG    + +  P  Q  GPG+   E  + P
Sbjct: 206 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP 265

Query: 221 HDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGI 280
            DY+ +A+L+  C  WP  I+A   AV  R +L +GD+  A+   R A+  S ++L  G+
Sbjct: 266 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV 325

Query: 281 AAMVLCTILTV 291
             ++   ++ +
Sbjct: 326 LIIIASCVINL 336



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 27/103 (26%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEP-PAPPPQAAPSSHHHHHHHYHQSGTATLPRL 59
           +S E +    S   ++ PP  AP+P  +P P P  Q  P           +  T  +   
Sbjct: 114 VSKEATADQGSRLESAAPPEPAPEPAPQPDPRPDSQPTPKPALQPELPTQEDPTPEILSE 173

Query: 60  GAGGLASSAATAQRGPSSSATLPRPPHHAPPG----PAAGAPP 98
             G    + A            P P  H+PP     PA GAPP
Sbjct: 174 SVGEKQENGAVVPLQAGDGEEGPAPEPHSPPSKKSPPANGAPP 216


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 71/217 (32%), Positives = 81/217 (37%), Gaps = 38/217 (17%)

Query: 17   PPPYNAPQ--PPAEPPAP-----PPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLAS--- 66
            PPP    +  PP  PP P     PP   P +           G   LP L   G+     
Sbjct: 899  PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA-----------GILPLPPLPGAGIPPPPP 947

Query: 67   --SAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPP 124
               AA     P   A +P PP    P P AG PPP       +PP P L       P PP
Sbjct: 948  LPGAAIPPPPPLPGAGIPLPP----PLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPP 1001

Query: 125  PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQPCTAYVPVYP 183
            P P A  PPPP P   A  P       AG     PL G  + P  PL   P     P  P
Sbjct: 1002 PLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGAGIPPPPP 1057

Query: 184  VGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
            +  P AG  P      + +PPPP  PG  +  P  PP
Sbjct: 1058 L--PGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPP 1090



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 66/215 (30%), Positives = 79/215 (36%), Gaps = 23/215 (10%)

Query: 17   PPPY---NAPQPPAEPPA--PPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
            PPP      P PP  P A  PPP   P +          +G    P L   G+       
Sbjct: 1022 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081

Query: 72   QRG-----PSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPP 126
              G     P   A +P PP    P P  G PPP       +PP P L       P PPP 
Sbjct: 1082 GAGIPPPPPLPGAGIPPPP----PLPGVGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPL 1135

Query: 127  PAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQPCTAYVPVYPVG 185
            P A  PPPP   +    P   +P  AG     PL G  + P  PL         P+  VG
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194

Query: 186  TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
             P     PG     + +PPPP  PG+ +     PP
Sbjct: 1195 IPPPPPLPG-----AGIPPPPPLPGMGIPPAPAPP 1224



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 70/227 (30%), Positives = 82/227 (36%), Gaps = 28/227 (12%)

Query: 8    LPDSVPHTSPPP------YNAPQPPAEPPA--PPPQAAPSSHHHHHHHYHQSGTATLPRL 59
            LP  +P    PP         P PP  P A  PPP   P +          +G    P L
Sbjct: 966  LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025

Query: 60   GAGGLASSAATAQRG-----PSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQ 114
               G+         G     P   A +P PP    P P AG PPP       +PP P L 
Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1081

Query: 115  ETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQ 173
                  P PPP P A  PPPP        P   +P  AG     PL G  + P  PL   
Sbjct: 1082 GAGI--PPPPPLPGAGIPPPPPLPGVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGA 1138

Query: 174  PCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
                  P+  VG P     PG     + +PPPP  PG  +  P  PP
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLPG-----AGIPPPPPLPGAGI--PPPPP 1178



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 69/215 (32%), Positives = 80/215 (37%), Gaps = 24/215 (11%)

Query: 17   PPPY---NAPQPPAEPPA--PPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
            PPP      P PP  P A  PPP   P +          +G    P L   G+       
Sbjct: 956  PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--- 1012

Query: 72   QRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAA 131
               P   A +P PP    P P AG PPP       +PP P L       P PPP P A  
Sbjct: 1013 ---PLPGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGI 1063

Query: 132  PPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQPCTAYVPVYPVGTPYAG 190
            PPPP P   A  P       AG     PL G  + P  PL   P     P  P+  P AG
Sbjct: 1064 PPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGVGIPPPPPL--PGAG 1117

Query: 191  GTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
              P      + +PPPP  PG  +  P   P   +P
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP 1152



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 68/215 (31%), Positives = 77/215 (35%), Gaps = 25/215 (11%)

Query: 17   PPPY---NAPQPPAEPPA--PPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
            PPP      P PP  P A  PPP   P +          +G    P L   G+       
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1070

Query: 72   QRG-----PSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPP 126
              G     P   A +P PP    P P AG PPP       +PP P L       P PPP 
Sbjct: 1071 GAGIPPPPPLPGAGIPPPP----PLPGAGIPPPPPLPGVGIPPPPPLPGAGI--PPPPPL 1124

Query: 127  PAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQPCTAYVPVYPVG 185
            P A  PPPP P   A  P        G     PL G  + P  PL         P+  VG
Sbjct: 1125 PGAGIPPPP-PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1183

Query: 186  TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
             P     PG       +PPPP  PG  +  P  PP
Sbjct: 1184 IPPPPPLPG-----VGIPPPPPLPGAGI--PPPPP 1211



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 59/214 (27%), Positives = 78/214 (36%), Gaps = 32/214 (14%)

Query: 11  SVPHTSPPP---YNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASS 67
           S+    PPP   ++A Q   +P + PP +  +     H H   S       + +      
Sbjct: 806 SISQPPPPPSLLWSAGQ--GQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863

Query: 68  AATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPP 127
             ++   P      P PP    P P    P      +P+ PP   LQ T    P PPP P
Sbjct: 864 TESSSSMPGLGMVPPPPP----PLPGMTVPTLPSTAIPQPPP---LQGTEMLPPPPPPLP 916

Query: 128 AAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPL-GGYVAPGYPLQLQPCTAYVPVYPVGT 186
            A  PPPP        PG      AG +   PL G  + P  PL         P+   G 
Sbjct: 917 GAGIPPPP------PLPG------AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI 964

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
           P     PG     + +PPPP  PG  +  P  PP
Sbjct: 965 PLPPPLPG-----AGIPPPPPLPGAGI--PPPPP 991



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/192 (27%), Positives = 65/192 (33%), Gaps = 30/192 (15%)

Query: 17   PPPY---NAPQPPAEPPA--PPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
            PPP      P PP  P A  PPP   P +         + G    P L   G+       
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169

Query: 72   QRGPSSSATLPR---PPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRF-EGPLPP-PP 126
              G      LP    PP   PP P  G PPP       +PP P L        P PP PP
Sbjct: 1170 GAGIPPPPPLPGVGIPP--PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227

Query: 127  PAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQL-------------- 172
            P    PPP  P      P  +    + T+ T  + G++ P  P  L              
Sbjct: 1228 PGTGIPPP--PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQ 1285

Query: 173  --QPCTAYVPVY 182
              +PC    P+Y
Sbjct: 1286 PIEPCRPMKPLY 1297


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 62/226 (27%), Positives = 73/226 (32%), Gaps = 12/226 (5%)

Query: 9    PDSVPHTSPPPYNAPQPP-AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASS 67
            P +   T+PPP   P PP      PPP   PS           + T + P        S 
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTT----TPSP 1479

Query: 68   AATAQRGPSSSATLPRP-PHHAPPGPAAGAPPPGCATL-PRMPPDPYLQETRFEGPLPPP 125
              T    P+++ T P P    +PP      PP    TL P   P P    T    P   P
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP 1539

Query: 126  PPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVG 185
             P    P  P P  T   P    P+   T  T P      P  P    P     P     
Sbjct: 1540 SPPTTTPITP-PTSTTTLPPTTTPSPPPTTTTTP-PPTTTPSPPTTTTPSP---PTITTT 1594

Query: 186  TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTT 231
            TP    TP     T+T PPP   P      P  PP     +   TT
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 58/226 (25%), Positives = 73/226 (32%), Gaps = 9/226 (3%)

Query: 15   TSPPPYNAPQPPAEPPAPP---PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
            T+PPP   P PP   P+PP   P    ++          S   T P        +   T 
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521

Query: 72   QRGPSSSATLPRPPHHAPPGPAAG--APPPGCATLP--RMPPDPYLQETRFEGPLPPPPP 127
               P ++ T   PP   P  P      PP    TLP    P  P    T       P PP
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581

Query: 128  AAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTP 187
                P PP    T   P         T  T P     +P     + P T+   + P  TP
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641

Query: 188  YAGGTPGGTGVTSTLPPPP--QGPGLALLEPRRPPHDYMPIAVLTT 231
                T   T   +T P PP    P   +     PP    P + +TT
Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 72/249 (28%), Positives = 85/249 (34%), Gaps = 45/249 (18%)

Query: 9    PDSVPHTSPPPYNAPQPPA----EPPA-----PPPQAAPSSHHHHHHHYHQSGTATLPRL 59
            P     T+PPP   P PP      PP      PPP   PS           + T T P  
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP--------TTTTTTPPPT 1615

Query: 60   GAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMP----PDPYLQE 115
                 +    T    P+S+ TLP     +PP      PPP   T P  P    P P +  
Sbjct: 1616 TTP--SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP--TTTPSPPTTTTPSPPITT 1671

Query: 116  TRFEGP-LPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQP 174
            T    P   P  P    P PP    T  +P    P+   T  T P      P  P    P
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSP-TTTPSSPITTTTTP-SSTTTPSPP----P 1725

Query: 175  CTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLAL--LEPRRPPHDYMPIAVL--T 230
             T   P  P  TP    +P  T +T TLPP      L    L P   P  + P +    T
Sbjct: 1726 TTMTTP-SPTTTP----SPPTTTMT-TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779

Query: 231  TIC---CFW 236
            T C   C W
Sbjct: 1780 TPCVPLCNW 1788



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 51/205 (24%), Positives = 63/205 (30%), Gaps = 26/205 (12%)

Query: 8    LPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASS 67
            LP +   + PP      PP   P+PP    PS           + T T P          
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP---------PTITTTTP---------P 1597

Query: 68   AATAQRGPSSSATLPRP-PHHAPPGPAAGAPPPGCATLP--RMPPDPYLQETRFEGPLPP 124
              T    P+++ T P P    +PP      PP    TLP    P  P    T       P
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1657

Query: 125  PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPV 184
             PP    P PP    T   P     +   T  + P      P         T   P+   
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS-----PTTTPSSPITTT 1712

Query: 185  GTPYAGGTPGGTGVTSTLPPPPQGP 209
             TP +  TP     T T P P   P
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTP 1737



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 56/226 (24%), Positives = 70/226 (30%), Gaps = 13/226 (5%)

Query: 16   SPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGP 75
            SPP      PP      PP   PS           + T T P            T    P
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSP---------PTTTTTTPPPTTTPSPPITTTTTPPP 1450

Query: 76   SSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPP 135
            +++ + P      PP     +PP    + P   P P    T    P   P P    P  P
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 136  APAQTAQAPGFVVPTHAGTVGTLPLGGYV-APGYPLQLQPCTAYVPVYPVGTPYAGGTPG 194
             PA T   P    P+   T  T P      +P     + P T+   + P  TP    T  
Sbjct: 1511 -PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569

Query: 195  GTGVTSTLPPPP--QGPGLALLEPRRPPHDYMPIAVLTTICCFWPT 238
             T   +T P PP    P    +    PP    P    TT     PT
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 45/184 (24%), Positives = 57/184 (30%), Gaps = 17/184 (9%)

Query: 23   PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLP 82
            P PP   P+PPP                + T TLP        ++  T    P+++ + P
Sbjct: 1399 PSPPTTTPSPPP----------------TSTTTLPPTTTPSPPTTTTTTPP-PTTTPSPP 1441

Query: 83   RPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQ 142
                  PP     +PP    T P     P    T    P   P P       P P  T  
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501

Query: 143  APGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTL 202
             P     T   +  TLP     +P       P     P  P  TP    T   T   +T 
Sbjct: 1502 PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1561

Query: 203  PPPP 206
            P PP
Sbjct: 1562 PSPP 1565



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 38/167 (22%), Positives = 49/167 (29%), Gaps = 28/167 (16%)

Query: 16   SPPPYNAPQPPAEP--------PAPPP---QAAPSSHHHHHHHYHQSGTATLPRLGAGGL 64
            +P P     P   P        P P P   Q  P +H         + TA +  L     
Sbjct: 4164 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH---------TSTAPIAELTTSNP 4214

Query: 65   ASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPD-PYLQETRFEGPLP 123
               ++T Q   S+S+ L                PP        PP  P    T   G   
Sbjct: 4215 PPESSTPQTSRSTSSPLTEST------TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTL 4268

Query: 124  PPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPL 170
             PPP+    PP  P +         PT   TV T     +     PL
Sbjct: 4269 SPPPSTTTSPPGTPTRGTTTGSSSAPT-PSTVQTTTTSAWTPTPTPL 4314



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 42/157 (26%), Positives = 47/157 (29%), Gaps = 26/157 (16%)

Query: 85   PHHAPPGPAAGAPPPGCATLPRMP-PDPYLQETRFEGPL-------PPPPPAAAAPPPPA 136
            P   P G       P   T    P P P   +T    P+       P P P     P   
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130

Query: 137  PAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGT 196
            P  T      V PT   T    P              P T    V P  TP    TP  T
Sbjct: 4131 PITTTTT---VTPTPTPTGTQTPT-----------TTPITTTTTVTPTPTPTGTQTPTTT 4176

Query: 197  GV--TSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTT 231
             +  T+T+ P P   G     P        PIA LTT
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHT--STAPIAELTT 4211



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 30/125 (24%), Positives = 34/125 (27%), Gaps = 16/125 (12%)

Query: 82   PRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTA 141
            P PP   P        P    T  + P    +  T    P P P         P    T 
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952

Query: 142  QAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTST 201
              P    PT  GT                   P T    V P  TP    TP  T +T+T
Sbjct: 1953 VTP---TPTPTGTQTPTTT-------------PITTTTTVTPTPTPTGTQTPTTTPITTT 1996

Query: 202  LPPPP 206
                P
Sbjct: 1997 TTVTP 2001


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 52/160 (32%), Positives = 64/160 (40%), Gaps = 24/160 (15%)

Query: 2   SSEKSGLPDSVPHTSPPPY-NAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           S  +  +P   P  + PP  + P+P A   APPP   PS           SG    PRL 
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335

Query: 61  AGGLASSAATAQR-GPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPP---------- 109
              L+ S++T     P  S  LP PP   PP P    PP     LP  PP          
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD-PPGRSGPLPPPPPVSRNGSTSRA 394

Query: 110 ---DPYLQ-----ETRFEGPLPPPPP---AAAAPPPPAPA 138
               P L      ++   GP PP PP   +A APPPP P+
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 64/224 (28%), Positives = 84/224 (37%), Gaps = 34/224 (15%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           + S+   +P  VP T  P  ++P     PP P     PS            GTA    LG
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA----LG 231

Query: 61  AGGLASSAATAQRGPSSSATLPRPPHHA------PPGPAAG----------APPPGCATL 104
            G +  S  ++    S+   LP  P  A      PP P  G           PPP     
Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291

Query: 105 PRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTA--QAPGFVVPTHAGTVGTLPLGG 162
           P +P  P       + P PPPPP+   PPP  P+ +   + P       + +  T PL  
Sbjct: 292 PPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-- 348

Query: 163 YVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPP 206
             +PG    L P  +  P  PV  P     PG +G    LPPPP
Sbjct: 349 -PSPGRSGPLPPPPSERPPPPVRDP-----PGRSG---PLPPPP 383



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 61/228 (26%), Positives = 78/228 (34%), Gaps = 38/228 (16%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQPPA-----EPPAPPPQAA--PSSHHHHHHHYHQSGTA 54
           S  +S L  S P ++ PP   P  P+     +PP PPP     PS H            A
Sbjct: 234 SIRQSPLSSSSPFSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE----------A 281

Query: 55  TLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQ 114
             P           +T +   SS A  P PP   P  P       G    PR+P     +
Sbjct: 282 VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ----R 337

Query: 115 ETRFEGPLPP-PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVA-PGYPLQL 172
                   PP P P  + P PP P++    P   V    G  G LP    V+  G   + 
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPP---VRDPPGRSGPLPPPPPVSRNGSTSRA 394

Query: 173 QPCTAYVPVYP-VGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRP 219
            P T  +P    V +P +G  P         P PP  P      P  P
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRP---------PLPPDRPSAGAPPPPPP 433



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 37/132 (28%), Positives = 48/132 (36%), Gaps = 48/132 (36%)

Query: 17  PPPYNAPQPPAEPP----APPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           PPP   P PP   P     P P   P S +        S +  LP       A+    ++
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNG-------STSRALP-------ATPQLPSR 404

Query: 73  RGPSSSATLPRPPHHAPPGPAAGAPPPG---------------------------CATLP 105
            G  S  + PRPP   P  P+AGAPPP                             + LP
Sbjct: 405 SGVDSPRSGPRPPL-PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLP 463

Query: 106 RMPPDPYLQETR 117
             PP+PY+Q T+
Sbjct: 464 --PPEPYVQTTK 473


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 52/160 (32%), Positives = 64/160 (40%), Gaps = 24/160 (15%)

Query: 2   SSEKSGLPDSVPHTSPPPY-NAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           S  +  +P   P  + PP  + P+P A   APPP   PS           SG    PRL 
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP 335

Query: 61  AGGLASSAATAQR-GPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPP---------- 109
              L+ S++T     P  S  LP PP   PP P    PP     LP  PP          
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD-PPGRSGPLPPPPPVSRNGSTSRA 394

Query: 110 ---DPYLQ-----ETRFEGPLPPPPP---AAAAPPPPAPA 138
               P L      ++   GP PP PP   +A APPPP P+
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 64/224 (28%), Positives = 84/224 (37%), Gaps = 34/224 (15%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           + S+   +P  VP T  P  ++P     PP P     PS            GTA    LG
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA----LG 231

Query: 61  AGGLASSAATAQRGPSSSATLPRPPHHA------PPGPAAG----------APPPGCATL 104
            G +  S  ++    S+   LP  P  A      PP P  G           PPP     
Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291

Query: 105 PRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTA--QAPGFVVPTHAGTVGTLPLGG 162
           P +P  P       + P PPPPP+   PPP  P+ +   + P       + +  T PL  
Sbjct: 292 PPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL-- 348

Query: 163 YVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPP 206
             +PG    L P  +  P  PV  P     PG +G    LPPPP
Sbjct: 349 -PSPGRSGPLPPPPSERPPPPVRDP-----PGRSG---PLPPPP 383



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 61/228 (26%), Positives = 78/228 (34%), Gaps = 38/228 (16%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQPPA-----EPPAPPPQAA--PSSHHHHHHHYHQSGTA 54
           S  +S L  S P ++ PP   P  P+     +PP PPP     PS H            A
Sbjct: 234 SIRQSPLSSSSPFSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE----------A 281

Query: 55  TLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQ 114
             P           +T +   SS A  P PP   P  P       G    PR+P     +
Sbjct: 282 VPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ----R 337

Query: 115 ETRFEGPLPP-PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVA-PGYPLQL 172
                   PP P P  + P PP P++    P   V    G  G LP    V+  G   + 
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPP---VRDPPGRSGPLPPPPPVSRNGSTSRA 394

Query: 173 QPCTAYVPVYP-VGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRP 219
            P T  +P    V +P +G  P         P PP  P      P  P
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRP---------PLPPDRPSAGAPPPPPP 433



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 37/132 (28%), Positives = 48/132 (36%), Gaps = 48/132 (36%)

Query: 17  PPPYNAPQPPAEPP----APPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           PPP   P PP   P     P P   P S +        S +  LP       A+    ++
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNG-------STSRALP-------ATPQLPSR 404

Query: 73  RGPSSSATLPRPPHHAPPGPAAGAPPPG---------------------------CATLP 105
            G  S  + PRPP   P  P+AGAPPP                             + LP
Sbjct: 405 SGVDSPRSGPRPPL-PPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLP 463

Query: 106 RMPPDPYLQETR 117
             PP+PY+Q T+
Sbjct: 464 --PPEPYVQTTK 473


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 47/130 (36%), Positives = 52/130 (40%), Gaps = 27/130 (20%)

Query: 9   PDSVPHTSPP---PYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLA 65
           P + P  SPP   P  AP PPA PP PPP                      P +G G   
Sbjct: 301 PPAPPLGSPPGPKPGFAP-PPAPPPPPPPMIGIPPPP--------------PPVGFGSPG 345

Query: 66  SSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPP 125
           +        PS  +  P P   APP P    PPP  A  P +PP P  Q T    P PPP
Sbjct: 346 TPPP-----PSPPSFPPHPDFAAPPPP----PPPPAADYPTLPPPPLSQPTGGAPPPPPP 396

Query: 126 PPAAAAPPPP 135
           PP    PPPP
Sbjct: 397 PPPPGPPPPP 406



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 65/214 (30%), Positives = 77/214 (35%), Gaps = 65/214 (30%)

Query: 17  PPPYN----APQPP-AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATA 71
           PPP +    +P P  +E   PPP   P+   +   +   SG A       G   SS  + 
Sbjct: 248 PPPQSDSASSPSPSFSEDNLPPP---PAEFSYPVDNQRGSGLA-------GPKRSSVVSP 297

Query: 72  QRGPSSSATLPRPPHHAPPGPAAG-APPPGCATLPRMPPDPYLQETRFEGPLPPPPPAA- 129
              P      P PP  +PPGP  G APPP     P  PP P +      G  PPPPP   
Sbjct: 298 SHPP------PAPPLGSPPGPKPGFAPPPA----PPPPPPPMI------GIPPPPPPVGF 341

Query: 130 ---AAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGT 186
                PPPP+P      P F  P         P     A  YP         +P  P+  
Sbjct: 342 GSPGTPPPPSPPSFPPHPDFAAPP--------PPPPPPAADYPT--------LPPPPLSQ 385

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
           P  G  P         PPPP  PG     P  PP
Sbjct: 386 PTGGAPPP--------PPPPPPPG-----PPPPP 406



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 40/138 (28%), Positives = 45/138 (32%), Gaps = 32/138 (23%)

Query: 9   PDSVPHTSPPPYNAPQPP-----AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGG 63
           P + P   PP    P PP       P  PPP + PS   H                    
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH-------------------- 358

Query: 64  LASSAATAQRGPSSSA---TLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120
               AA     P  +A   TLP PP   P G   GAPPP     P  PP P       + 
Sbjct: 359 -PDFAAPPPPPPPPAADYPTLPPPPLSQPTG---GAPPPPPPPPPPGPPPPPFTGADGQP 414

Query: 121 PLPPPPPAAAAPPPPAPA 138
            +PPP      P    PA
Sbjct: 415 AIPPPLSDTTKPKSSLPA 432


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 66/214 (30%), Positives = 77/214 (35%), Gaps = 41/214 (19%)

Query: 2   SSEKSGLPDSVPHTS--PPPYNAPQPPAEPPAPP--PQAAPSSHHHHHHHYHQSGTATLP 57
           SS++   P SVP +    PP   P P   PPAPP  P   P+            G    P
Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT------------GLPPGP 434

Query: 58  RLGAGG-LASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQET 116
             GA   L        RGP      P PP   PPGP  G PPPG      +PP P     
Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG-PPPG------LPPGP----- 482

Query: 117 RFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCT 176
                 PP  P    PPP  P      PG + P     +G  P G  + P  PL   P  
Sbjct: 483 ------PPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG--LFPPAPLP-NPGV 533

Query: 177 AYVPVYPVGTPYAGGTPGGT---GVTSTLPPPPQ 207
              P   +  P A  T   T     T+T+   PQ
Sbjct: 534 LSAPPNLIQRPKADDTSAATIEKKATATISAKPQ 567



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 60/196 (30%), Positives = 69/196 (35%), Gaps = 63/196 (32%)

Query: 28  EPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHH 87
           E  +   +A   S   H    H  GT+T            A++ Q+ P  S     PP  
Sbjct: 358 EDDSDDSEAEKQSQKQHKEESHSDGTST------------ASSQQQAPPQSV----PPSQ 401

Query: 88  APPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFV 147
               P  G PP G       PP P         PL PP P    PP P P     AP F+
Sbjct: 402 IQAPPMPGPPPLG------PPPAP---------PLRPPGPPTGLPPGPPPG----APPFL 442

Query: 148 VPTHA-GTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPP-- 204
            P    G  G LP    + PG P          P  P G P  G  PG       LPP  
Sbjct: 443 RPPGMPGLRGPLPR--LLPPGPP----------PGRPPGPP-PGPPPG-------LPPGP 482

Query: 205 PPQGPGLALLEPRRPP 220
           PP+GP      PR PP
Sbjct: 483 PPRGP-----PPRLPP 493



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 37/149 (24%), Positives = 42/149 (28%), Gaps = 56/149 (37%)

Query: 1   MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
           M   +  LP  +P   PP      PP  PP  PP   P                      
Sbjct: 447 MPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPP---------------------- 484

Query: 61  AGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPP-PGCATLPRMPPDPYLQETRFE 119
                       RGP        PP   PP P    PP PG    P +P           
Sbjct: 485 ------------RGP--------PPRLPPPAPPGIPPPRPGMMRPPLVP----------- 513

Query: 120 GPLPPPPPAAAAPPP-PAPAQTAQAPGFV 147
            PL P PP    P P P P   +  P  +
Sbjct: 514 -PLGPAPPGLFPPAPLPNPGVLSAPPNLI 541



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 17/79 (21%)

Query: 56  LPRLGAGGLASSAATAQRGPSSSAT---------LPR-PPHHAPPGPAAGAPPPGCATLP 105
           +P  GA   +    T+  GP + A          +PR PP   PPGP  G PPP    + 
Sbjct: 156 IPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQM- 214

Query: 106 RMPPDPYLQETRFEGPLPP 124
                 Y ++  F   LPP
Sbjct: 215 ------YGRKVGFALDLPP 227


>gi|169178462 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 93

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 37/86 (43%), Positives = 48/86 (55%)

Query: 209 PGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDMVSAEIASREA 268
           PG A +E R  P DYM  +VL T+ C   TG+IAI  + + R AL RGD+  AE ASR+A
Sbjct: 5   PGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEARAALGRGDLAQAEEASRKA 64

Query: 269 RNFSFISLAVGIAAMVLCTILTVVII 294
           R+    SL  G+       I  VV +
Sbjct: 65  RSLVLFSLLFGVFVSTSWVIYVVVAL 90


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 72/237 (30%), Positives = 85/237 (35%), Gaps = 39/237 (16%)

Query: 7    GLPDSVPH----TSPPPYNAPQPPAEPPAPP-PQAAPSSHHHHHHHYHQSGTATLPRLGA 61
            G P + P     ++PP    P P   P A P P+ AP++             ATLP    
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP-----------AATLPSPKG 1069

Query: 62   GGLASSAATAQRGPSSSATLPR------PPHHAPPGPAAGAPPP--GCATLPRM--PPDP 111
            G    S   A   P+++   P+       P  AP  PAA  P P  G AT P    P  P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 112  YLQETRFEGPLPPPPPAAA-----APPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAP 166
                   +G L  PPP  A     A PP      A  P    PT        P GG   P
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189

Query: 167  GYPLQLQPCTAYVPVYPVG---TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
              P       A  P  P G   TP   G P     T   PP P+G GLA   P+  P
Sbjct: 1190 S-PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT---PPSPKG-GLATPSPKGAP 1241



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 75/243 (30%), Positives = 85/243 (34%), Gaps = 60/243 (24%)

Query: 3    SEKSGLPDSVPHTSPPPYNAPQPPAEPP--------APPPQAAPSSHHHHHHHYHQSGTA 54
            S K GL       +PPP  AP  PA  P         PPP+ AP++             A
Sbjct: 1135 SPKGGL------ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT------------PA 1176

Query: 55   TLPRLGAGGLASSA------ATAQRGPSSSATLPRP-PHHAPPGPAAGAPPP-------- 99
              P    GGLA+ +        A   PS    L  P P  AP  PAA  P P        
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 100  --GCATLPRM-PPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVG 156
              G  T P   PP P        GP  PPP  A  P PPA    +   G   P H G   
Sbjct: 1237 PKGAPTTPAATPPSPK------GGPATPPPKGA--PTPPAATPPSLKGGLATPPHKGA-- 1286

Query: 157  TLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEP 216
              P    V P  P +  P T+  P     TP A   P   G   T PPP   P    + P
Sbjct: 1287 --PNPAVVTPPSP-KGGPATS--PPKGAPTPPAATPPSPKGSPGT-PPPKGAPTPPAVTP 1340

Query: 217  RRP 219
              P
Sbjct: 1341 PSP 1343



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 64/220 (29%), Positives = 82/220 (37%), Gaps = 28/220 (12%)

Query: 9    PDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
            P   P  +P P  A  PPA  P P P+ +P++               LP+      A++ 
Sbjct: 1019 PKGSPAATPFPKGASTPPAATP-PSPKGSPAA-------------TPLPKGAPTTPAATL 1064

Query: 69   ATAQRGPSSSAT--LPRPPHHAPPGPAAG--APPPGCATLPRMPPDPYLQETRFEGPLPP 124
             + + GP++ +    P PP   PP P  G   P P  A +P     P  +      P   
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 125  PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCT-AYVPVYP 183
             P   AA PP      A  P    PT        P GG   P  P +  P T A  P  P
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP--PPKGAPTTPAATPPSP 1182

Query: 184  VG---TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
             G   TP   G P     T   PP P+G GLA   P+  P
Sbjct: 1183 KGGLATPSPKGAPTTPAAT---PPSPKG-GLATPSPKGAP 1218



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 71/232 (30%), Positives = 82/232 (35%), Gaps = 29/232 (12%)

Query: 9    PDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGA------G 62
            P  +P  SP P  AP PPA  P P P+  P++          + T   P+ G       G
Sbjct: 927  PKGIP-ASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984

Query: 63   GLASSAATAQRGPSSSAT-----LPRPPHHAPPGPA---AGAPPPGCATLPRMPPDPYLQ 114
                 AAT        AT      P PP   PP P    A  P P  A+ P     P  +
Sbjct: 985  APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044

Query: 115  ETRFEGPLP---PPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQ 171
             +    PLP   P  PAA  P P     T    G   PT        P GG   P  P  
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG--APTPPAATPPSPKGGPATPS-PKG 1101

Query: 172  LQPCTAYVPVYPVG---TPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
                 A  P  P G   TP   G P     T   PP P+G GLA   P+  P
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAAT---PPSPKG-GLATPPPKGAP 1149



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 63/227 (27%), Positives = 78/227 (34%), Gaps = 26/227 (11%)

Query: 16   SPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGP 75
            +PPP  AP PPA   A PP          H         T P    G   S    A   P
Sbjct: 1257 TPPPKGAPTPPA---ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313

Query: 76   SSSATLPR------PPHHAPPGPAAGAP-PPGCATLPRMPPDPYLQETRFEGPLPPPPPA 128
            +++   P+      PP  AP  PA   P P G  TLP   P      T       P PPA
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373

Query: 129  AAAPPPPAPAQTAQAP--GFVVPTHAG---TVGTLPLGGYVAPGYPLQLQPCT------- 176
            A       PA T  +P  G  +P+  G   +   +PL    AP  P+  +          
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433

Query: 177  ---AYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
               A  PV     P A   P G   T +    P  P +    P+ PP
Sbjct: 1434 TPPAVTPVSLKKAP-ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 61/213 (28%), Positives = 79/213 (37%), Gaps = 19/213 (8%)

Query: 15   TSPPPYNAPQPPAEPPAPP------PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
            T P P  AP P A  P  P      P+  P+    +   + + G AT     A  L+ ++
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQAPALSMTS 915

Query: 69   ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPA 128
            ++ ++  ++ A    P   A P P  GAP P  AT    PP P            P PPA
Sbjct: 916  SSPKKARATPAPKGIP---ASPSPK-GAPTPPAAT----PPSPKGGPATPSPKWAPTPPA 967

Query: 129  AAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPY 188
            A  P P     T    G   PT        P GG   P  P       A  P  P G+P 
Sbjct: 968  ATPPSPKGGPATPSPKG--APTPPAATPPSPKGGPATPS-PKGAPTPPAVTPPSPKGSPA 1024

Query: 189  AGGTPGGTGV-TSTLPPPPQGPGLALLEPRRPP 220
            A   P G     +  PP P+G   A   P+  P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/232 (25%), Positives = 84/232 (36%), Gaps = 39/232 (16%)

Query: 11   SVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAAT 70
            ++P T+P     P  P+    P P AA  S        H+ G A  P     G A    +
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPS--------HKGGPAMTPPSPKRGPA--IPS 1397

Query: 71   AQRGPSSSATLPRPPHHAPPGP----AAGAPPPGCATLPRMPP--------------DPY 112
             +  P+S A +P  P  AP  P     A  P  G  T P + P               P 
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457

Query: 113  LQETRFEGPLPP-PPPAAAAPPPPAPAQTAQAPGFVVPTHAGT-VGTLPLGGYVAPGYPL 170
               ++ +  LP   PP+   PP P    T+ +P     T A     TLP    V P  P 
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA---VIPSSPK 1514

Query: 171  QL--QPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
            ++   P +   P+ P  T  +  TP        L P    P + +  P++ P
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP----PAMTVPSPKKTP 1562



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 61/240 (25%), Positives = 80/240 (33%), Gaps = 49/240 (20%)

Query: 15   TSPPPYNAPQPPA--------EPPAPPPQAAPSSHHHHHHHYHQSGT----------ATL 56
            TSP P  AP PPA         P  P P+  P+S          S T          AT+
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665

Query: 57   PRLGAGGLASSAATAQR------GPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPD 110
            P+   G  A    TA +       P S+  +  P    P    +       AT P + PD
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS------ATSPPICPD 1719

Query: 111  PYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQA-------PGFVVPTHAGTVGTLPLGGY 163
            P  +    +GPL    PA   P     ++TA+         G + P  +     L    +
Sbjct: 1720 PSAKNGS-KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778

Query: 164  VAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPP----PQGPGLALLEPRRP 219
                 P       +  P  PV  P A           TLPP     P  PGL L  P +P
Sbjct: 1779 -EKVLPKPESASVSAAPSPPVSLPLA------PSPVPTLPPKQQFLPSSPGLVLESPSKP 1831



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/170 (28%), Positives = 67/170 (39%), Gaps = 15/170 (8%)

Query: 50  QSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPP-PGCATLPRMP 108
           Q+ TA LP   A  L+ +AA  Q GP+        P   P   A  A P P  +T+   P
Sbjct: 20  QAETAVLPMSSA--LSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTP 77

Query: 109 PD-PYLQETRFEGPLPPPPPAAAAP--------PPPAPAQTAQAPGFVVPTHAGTVGTLP 159
            + P+ Q +   G   P   A  AP        PP +PA  A A   + PT  GT  +  
Sbjct: 78  LEVPFPQSS--SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA 135

Query: 160 LGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGP 209
               VA   P  +Q  +A+ P      P       G+ +T + P  P  P
Sbjct: 136 PLALVALA-PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP 184



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/179 (27%), Positives = 62/179 (34%), Gaps = 21/179 (11%)

Query: 61   AGGLASSAATAQRGPSSSATLPRPPHHAPPG---PAAGAP--PPGCATLPRMPPDPYLQE 115
            A  L  ++ + Q    S AT   P   +P G   P+A  P  P G    P+  P P +  
Sbjct: 833  ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892

Query: 116  TRF--EGPLPPPPPAAAA----PPPPAPAQTAQAPGFV--------VPTHAGTVGTLPLG 161
              F  EGP  P P  A A       P  A+   AP  +         PT        P G
Sbjct: 893  LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 162  GYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
            G   P  P       A  P  P G P      G     +  PP P+G G A   P+  P
Sbjct: 953  GPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPKGAP 1009



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 32/128 (25%), Positives = 39/128 (30%), Gaps = 26/128 (20%)

Query: 17   PPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPS 76
            PP    P P   P  P P+ AP               AT     A    +   +  +G  
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAP---------------ATPSSKEASSPPAVTPSTYKGAP 1594

Query: 77   SSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPA 136
            S   L  PP    P P     PP        PP P       +GP  P P      PP  
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVT-----PPSPE------KGPATPAPKGTPTSPPVT 1643

Query: 137  PAQTAQAP 144
            P+    +P
Sbjct: 1644 PSSLKDSP 1651


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 67/220 (30%), Positives = 85/220 (38%), Gaps = 45/220 (20%)

Query: 3   SEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAG 62
           S++  L D++P  SP   +A       P  PPQ  P S+  ++     S  + LP     
Sbjct: 2   SDEFSLADALPEHSPAKTSAVSNTK--PGQPPQGWPGSNPWNNPSAPSSVPSGLPP---- 55

Query: 63  GLASSAATAQRGPSSSATLPR-PPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGP 121
             +++ +T   GP+ +   P  PP   PPGP A  PP G +  P  P  PY   T     
Sbjct: 56  --SATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPP--PGGPYPAPT----- 106

Query: 122 LPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTL-PLG----GYVAPG----YPLQL 172
           +P P P    P P  P      P +  PT     G L P G    G  APG    YP   
Sbjct: 107 VPGPGPTGPYPTPNMPFPELPRP-YGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPN 165

Query: 173 QPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLA 212
            P       YP   PY              PPPPQ PG A
Sbjct: 166 MP-------YPSPGPYPA------------PPPPQAPGAA 186



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 64/204 (31%), Positives = 75/204 (36%), Gaps = 21/204 (10%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQP--PAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRL 59
           SS  SGLP S   ++ P   AP    P+ PP  PP   P+        +  SG +  P  
Sbjct: 47  SSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAP-------FPPSGPSCPPPG 99

Query: 60  GAGGLASSAATAQRGPSSSATLPRP----PHHAPPGPAAGAP--PPGCATLPRMPPDPYL 113
           G     +       GP  +  +P P    P+ AP  PAA  P  P G  +     P    
Sbjct: 100 GPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGG 159

Query: 114 QETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHA---GTVGTLPLGGYVAPG-YP 169
           Q      P P P P  A PPP AP      P   VP  A         P G Y  PG YP
Sbjct: 160 QYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYP 219

Query: 170 LQLQPCTAYVPVYPVGTPYAGGTP 193
               P    VP  P G P   G P
Sbjct: 220 TPSNP--FQVPSGPSGAPPMPGGP 241



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 11  SVPHTSPPPYNAPQPPAEPPAPPP---QAAPSSHHHHHHHYHQSGTATLPRLGAGGLASS 67
           ++P+ SP PY AP PP  P A PP      P         Y  + T + P  G     S+
Sbjct: 165 NMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPY-PAPTGSYPTPGLYPTPSN 223

Query: 68  AATAQRGPSSSATLPRPPH 86
                 GPS +  +P  PH
Sbjct: 224 PFQVPSGPSGAPPMPGGPH 242


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 64/236 (27%), Positives = 83/236 (35%), Gaps = 45/236 (19%)

Query: 14   HTSPPPYNAPQPPAEP-PAPPPQAAPSSHHH---------HHHHYHQSGTATLPRLGAGG 63
            HT+P P   P PP    P PPPQ  P+ + +           HH+     A  P    G 
Sbjct: 894  HTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIG- 952

Query: 64   LASSAATAQRGPSSSATLPRPPHHAPPGPA-AGAPPPGCATLPRMPPDPYLQETRFEGPL 122
                              P+P  H  P P+ A  P P    LP     P+L   +  G L
Sbjct: 953  ------------------PQPQPHPQPHPSQAFGPQPPQQPLPLQ--HPHLFPPQAPGLL 992

Query: 123  PPPPPAAAAP------PPPAPAQTAQAPGFV---VPTHAGTVGTLPLGGYVAPGYPLQLQ 173
            PP  P   AP       PP P  T   PG     +P H+G +     G    P  PL   
Sbjct: 993  PPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYG 1052

Query: 174  PCTAYVPVYPVGTPYAGGTPGGTGVTS----TLPPPPQGPGLALLEPRRPPHDYMP 225
            P  +  P+ P   P     P   G ++     +P P   PG   + PR P  +  P
Sbjct: 1053 PAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPP 1108



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 63/223 (28%), Positives = 74/223 (33%), Gaps = 54/223 (24%)

Query: 22   APQPPAEPPAPPPQAAPSSHHHHH-----HHYHQSGTATLPRLGAG------GLASSAAT 70
            AP P A P AP P   P+  +            Q G  + P +G G      GL S+   
Sbjct: 807  APGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPP 866

Query: 71   AQRGPS------------SSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRF 118
               GP              S   P P H AP      APPP C  +P  PP         
Sbjct: 867  QFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVP--PPQ-------- 916

Query: 119  EGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLP----------LGGYVAPGY 168
              PLP P    A    P PAQ   + G      A  +G  P            G   P  
Sbjct: 917  --PLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974

Query: 169  PLQLQPCTAYVP----VYPVGTPYA-GGTPGGTGVTSTLPPPP 206
            PL LQ    + P    + P  +PY     PG  G     PPPP
Sbjct: 975  PLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLG----QPPPP 1013



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 46/157 (29%), Positives = 50/157 (31%), Gaps = 29/157 (18%)

Query: 6    SGLPDS--VPHTSPPPYNAPQP---PAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLG 60
            SG+P     P   P P   PQP    A  P PP Q  P  H H             P   
Sbjct: 940  SGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPH-----------LFPPQA 988

Query: 61   AGGLASSAATAQRGPSSSATLPRPPHHAP--PGPAAGAPPPGCATLPRMPPDPYLQETRF 118
             G L   +             P PP H    PGPA    P     LP   P P       
Sbjct: 989  PGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP------- 1041

Query: 119  EGPLPPPPPAAAAPPPPAPAQTAQAPGFVV--PTHAG 153
              P PP PP A  P P       QA    +  P+ AG
Sbjct: 1042 --PQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAG 1076



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 44/148 (29%), Positives = 51/148 (34%), Gaps = 30/148 (20%)

Query: 82  PRPPHHAPPGPAAGAPPP----GCATLPRMPPDPYLQETR-----FEGPLPPP----PPA 128
           P      PP   AG   P    G AT    PP P+   T        GPLPP     P  
Sbjct: 742 PEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQ 801

Query: 129 AAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPV-GTP 187
              P  P P     APG  +              Y AP Y  +L       P + V  +P
Sbjct: 802 LIQPRAPGPHAMPVAPGPAL--------------YPAPAYTPELGLVPRSSPQHGVVSSP 847

Query: 188 YA--GGTPGGTGVTSTLPPPPQGPGLAL 213
           Y   G  P   G+ S  PP   GP LA+
Sbjct: 848 YVGVGPAPPVAGLPSAPPPQFSGPELAM 875



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 38/125 (30%), Positives = 50/125 (40%), Gaps = 42/125 (33%)

Query: 10   DSVP-HTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
            D +P H+   P+ +P PP +PP PP    P+              +T P +G      +A
Sbjct: 1025 DPLPAHSGALPFPSPGPP-QPPHPPLAYGPAP-------------STRP-MGP----QAA 1065

Query: 69   ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPA 128
                RGPSS+      PH  P    + AP PG                   GP+PP PPA
Sbjct: 1066 PLTIRGPSSAGQSTPSPHLVP----SPAPSPG------------------PGPVPPRPPA 1103

Query: 129  AAAPP 133
            A  PP
Sbjct: 1104 AEPPP 1108



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 9/44 (20%)

Query: 6    SGLPDS--VPHTSPPPYN-----APQPPAEPPAP--PPQAAPSS 40
            + LP+S  +P +SPPP +     APQP  EPP P  P    PSS
Sbjct: 1532 ASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSS 1575



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 6/52 (11%)

Query: 90   PGPAAGAPPPGC--ATLPRMPPDPYLQETRFEGPLPPPPPAAAAPP-PPAPA 138
            PGPA    PPG   A+LP   P P         PLP  P     PP P AP+
Sbjct: 1521 PGPAE---PPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPS 1569



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 21/95 (22%), Positives = 32/95 (33%), Gaps = 21/95 (22%)

Query: 26   PAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPP 85
            PAEPP  PP + P S                       + SS+      P   A  P+  
Sbjct: 1523 PAEPPGLPPASLPES---------------------TPIPSSSPPPLSSPLPEAPQPKEE 1561

Query: 86   HHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEG 120
               P  P++G P      L  + P+ +  ++   G
Sbjct: 1562 PPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRG 1596



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 4/104 (3%)

Query: 125 PPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPV 184
           PPP   AP P  P +  ++           + +LP      P  P       +  P++  
Sbjct: 716 PPPRPTAPKPLLPRRE-ESEAVEAGDPPEELRSLPPDMVAGPRLPDTF--LGSATPLHFP 772

Query: 185 GTPYAGGT-PGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIA 227
            +P+   T PG   ++  LPP        L++PR P    MP+A
Sbjct: 773 PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVA 816



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 9/82 (10%)

Query: 89   PPG----PAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAP 144
            PPG    P A  P P  A  P +PP    + T      PPP    ++P P AP    + P
Sbjct: 1509 PPGGLESPVASLPGP--AEPPGLPPASLPESTPIPSSSPPP---LSSPLPEAPQPKEEPP 1563

Query: 145  GFVVPTHAGTVGTLPLGGYVAP 166
                P+      +L L   + P
Sbjct: 1564 VPEAPSSGPPSSSLELLASLTP 1585



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 6/87 (6%)

Query: 9    PDSVPHTSPPPYNAPQPPAEPPAPPP----QAAPSSHHHHHHHYHQSGTATLPRLGAGGL 64
            P  VP  +P P   P PP  P A PP    + A ++         Q G    P  G   L
Sbjct: 1082 PHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLL 1141

Query: 65   ASSAATAQRG--PSSSATLPRPPHHAP 89
              +   A  G  P +   + R P+  P
Sbjct: 1142 QPTKVDAAEGRRPQALRLIERDPYEHP 1168


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 73/245 (29%), Positives = 87/245 (35%), Gaps = 76/245 (31%)

Query: 1   MSSEKSGLPDSVPHTSP---------------PPYNAP-----QPPAEPPAPPPQAAPSS 40
           +S+    +P SVP  +P               PP  AP      PP  PP PPP   P  
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 615

Query: 41  HHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPP-- 98
                     S   +LP    GG A S      G    AT+P PP   P G    +P   
Sbjct: 616 -------VCISSPPSLP----GGTAISPPPPLSG---DATIP-PPPPLPEGVGIPSPSSL 660

Query: 99  PGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTL 158
           PG   +P  PP P     R   P PP P +A  PPPP P          +P  AG    +
Sbjct: 661 PGGTAIP--PPPPLPGSARIPPPPPPLPGSAGIPPPPPP----------LPGEAG----M 704

Query: 159 PLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRR 218
           P      PG P               G P     PGG G+    PPPP G G+    P  
Sbjct: 705 PPPPPPLPGGP---------------GIPPPPPFPGGPGI----PPPPPGMGM----PPP 741

Query: 219 PPHDY 223
           PP  +
Sbjct: 742 PPFGF 746


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 73/245 (29%), Positives = 87/245 (35%), Gaps = 76/245 (31%)

Query: 1   MSSEKSGLPDSVPHTSP---------------PPYNAP-----QPPAEPPAPPPQAAPSS 40
           +S+    +P SVP  +P               PP  AP      PP  PP PPP   P  
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 624

Query: 41  HHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPP-- 98
                     S   +LP    GG A S      G    AT+P PP   P G    +P   
Sbjct: 625 -------VCISSPPSLP----GGTAISPPPPLSG---DATIP-PPPPLPEGVGIPSPSSL 669

Query: 99  PGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTL 158
           PG   +P  PP P     R   P PP P +A  PPPP P          +P  AG    +
Sbjct: 670 PGGTAIP--PPPPLPGSARIPPPPPPLPGSAGIPPPPPP----------LPGEAG----M 713

Query: 159 PLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRR 218
           P      PG P               G P     PGG G+    PPPP G G+    P  
Sbjct: 714 PPPPPPLPGGP---------------GIPPPPPFPGGPGI----PPPPPGMGM----PPP 750

Query: 219 PPHDY 223
           PP  +
Sbjct: 751 PPFGF 755


>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c1 [Homo sapiens]
          Length = 1105

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 48/142 (33%), Positives = 52/142 (36%), Gaps = 27/142 (19%)

Query: 6    SGLPDSVPHTSPPPY---NAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAG 62
            +G P  +PH  PPPY   +   PP  PP P     P S               +P     
Sbjct: 985  AGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGS--------------MMPGQHMP 1030

Query: 63   GLASSAATAQRGPSSSATLPRPPHHAP-PGPAAGAPPPGCATLPRMPPDPYLQETRFEGP 121
            G       A   PS S   P PP   P PG   G   P  A     PP P  Q       
Sbjct: 1031 GRMIPTVAANIHPSGSG--PTPPGMPPMPGNILGPRVPLTAPNGMYPPPPQQQP------ 1082

Query: 122  LPPPPPAAAAPPPPAPAQTAQA 143
             PPPPPA   PPPPAP   A A
Sbjct: 1083 -PPPPPADGVPPPPAPGPPASA 1103



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 44/147 (29%), Positives = 50/147 (34%), Gaps = 33/147 (22%)

Query: 82   PRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAP-PPPAPAQT 140
            P+  H    GP  G  P G A  P M P             PPP P      PPP P Q 
Sbjct: 967  PQQAHQHSGGP--GLAPLGAAGHPGMMPHQQ----------PPPYPLMHHQMPPPHPPQP 1014

Query: 141  AQ------------APGFVVPTHAGTV-----GTLPLGGYVAPGYPLQLQ-PCTAYVPVY 182
             Q             PG ++PT A  +     G  P G    PG  L  + P TA   +Y
Sbjct: 1015 GQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSGPTPPGMPPMPGNILGPRVPLTAPNGMY 1074

Query: 183  PVGTPYAGGTPGGTGVTSTLPPPPQGP 209
            P   P     P         PPP  GP
Sbjct: 1075 P--PPPQQQPPPPPPADGVPPPPAPGP 1099


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 61/215 (28%), Positives = 73/215 (33%), Gaps = 44/215 (20%)

Query: 15  TSPPPYN--APQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQ 72
           T+PP  N  AP PP  PP PPP   P                    L +     +   + 
Sbjct: 164 TAPPRPNVPAPPPPTPPPPPPPLPPP--------------------LPSSSPIKTPLVSP 203

Query: 73  RGPSSSATLP--RPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPP------ 124
            GP +   LP   PP    P P    PPP   T P +PP   L +   +  L P      
Sbjct: 204 PGPLTKGNLPVVAPPVPCAPPPPPPPPPP---TPPPLPPASVLSDKAVKPQLAPLHLPPI 260

Query: 125 PPPAAAAPP---------PPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPC 175
           PPP    PP         P +PAQ AQ P    P         P     AP  P  +   
Sbjct: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLP-GVNSS 319

Query: 176 TAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPG 210
           +   P  P  +P     P   G    LP PP  PG
Sbjct: 320 SETPPPLPPKSPSFQAPPQKAG-AQALPAPPAPPG 353



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 51/156 (32%), Positives = 56/156 (35%), Gaps = 32/156 (20%)

Query: 5   KSGLPDSVPHT--SPPPYNAPQPPAEPPAPP----------PQAAPSSHHHHHHHYHQSG 52
           K  LP   P    +PPP   P PP  PP PP          PQ AP      H       
Sbjct: 209 KGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL-----HLPPIPPP 263

Query: 53  TATLPRLGAGGL----ASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMP 108
              LP  G  GL    AS A  AQ  P+    LP     +P       P PG  +    P
Sbjct: 264 LPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323

Query: 109 PDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQAP 144
           P           PLPP  P+  APP  A AQ   AP
Sbjct: 324 P-----------PLPPKSPSFQAPPQKAGAQALPAP 348



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 60/208 (28%), Positives = 72/208 (34%), Gaps = 30/208 (14%)

Query: 31  APPPQAAPSSHHHHHHHYHQSGTATLPRLG---AGGLASSAATAQR---------GPSSS 78
           AP  +++  ++       +  G +T P LG   AGG        QR         GP S 
Sbjct: 70  APQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSR 129

Query: 79  ATLPRPPHHA-------PPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAA 131
           A  PR P+         P  P  G            PP P +       P PPPPP    
Sbjct: 130 APSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPL--- 186

Query: 132 PPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGG 191
            PPP P+ +      V P    T G LP+   VAP  P    P     P  P   P A  
Sbjct: 187 -PPPLPSSSPIKTPLVSPPGPLTKGNLPV---VAPPVPCAPPPPPPPPPPTPPPLPPA-S 241

Query: 192 TPGGTGVTSTLPP---PPQGPGLALLEP 216
                 V   L P   PP  P L LL P
Sbjct: 242 VLSDKAVKPQLAPLHLPPIPPPLPLLPP 269



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 55/168 (32%), Positives = 67/168 (39%), Gaps = 19/168 (11%)

Query: 57  PRLGAGGLASSAA-TAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQE 115
           PRLG    A  AA TA   P+    +P PP   PP P    PPP  ++ P   P      
Sbjct: 150 PRLGNTSEAHGAARTAPPRPN----VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG 205

Query: 116 TRFEGPLP---PPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQL 172
              +G LP   PP P A  PPPP P  T   P  + P  A  +    +   +A   PL L
Sbjct: 206 PLTKGNLPVVAPPVPCAPPPPPPPPPPT---PPPLPP--ASVLSDKAVKPQLA---PLHL 257

Query: 173 QPCTAYVPVY-PVGTPYAGGTPGGTGVTSTLP--PPPQGPGLALLEPR 217
            P    +P+  P G P     P      +  P  PPP  P  A   PR
Sbjct: 258 PPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPR 305



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 28/155 (18%)

Query: 7   GLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLAS 66
           G P      + P  +A +PPA PP  PP A+ S              A+LP     G+ S
Sbjct: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPR------------ASLPAPPLPGVNS 318

Query: 67  SAATAQRGPSSSATLPRPPHHAPPGPAAGAP-PPGCATLPRMPPDPYLQETRFEGP---- 121
           S+ T    P  S +   PP  A        P PPG          P+LQ+ R   P    
Sbjct: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGS--------QPFLQKKRHGRPGAGG 370

Query: 122 ---LPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAG 153
               PPP P A +P     +++ QA  +      G
Sbjct: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPG 405



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 58/218 (26%), Positives = 70/218 (32%), Gaps = 36/218 (16%)

Query: 12  VPHTSPPPYNAPQPP-AEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAAT 70
           VP   PPP   P PP   PP PPP A P S          + T++L R    G ++  A 
Sbjct: 3   VPPPPPPPLPPPPPPLGAPPPPPPSAPPVS----------TDTSSLRRADPKGRSALLAD 52

Query: 71  AQRGPSSSATLPRPPHHAP---PGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPP 127
            Q+G             AP             G A        P L +  F G  P   P
Sbjct: 53  IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDL-FAGGFPVLRP 111

Query: 128 AAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTP 187
           A       A  +T Q PG   P               +P  P +    T   P+ P  +P
Sbjct: 112 AGQR--DVAGGKTGQGPGSRAP---------------SPRLPNK----TISGPLIPPASP 150

Query: 188 YAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
             G T    G   T PP P  P      P  PP    P
Sbjct: 151 RLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPP 188



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 8/35 (22%)

Query: 104 LPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPA 138
           +P  PP P         PLPPPPP   APPPP P+
Sbjct: 1   MPVPPPPP--------PPLPPPPPPLGAPPPPPPS 27



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 13/34 (38%), Positives = 14/34 (41%)

Query: 121 PLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGT 154
           P+PPPPP    PPPP        P    P    T
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDT 35


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 64/212 (30%), Positives = 72/212 (33%), Gaps = 59/212 (27%)

Query: 13  PHTSPPPYNA----PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
           P   PPP+ A    P+PP  PP PP    P             G    P L         
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPP----------PPGQVLPPPLA-------- 264

Query: 69  ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPA 128
                GP +    P PP    PG   G PP G   LP  PP P        GP P PPP 
Sbjct: 265 -----GPPNRGDRP-PPPVLFPGQPFGQPPLG--PLPPGPPPP----VPGYGPPPGPPPP 312

Query: 129 AAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPY 188
              PPPP        PG   P   G +G            PL L P   ++P  P G P 
Sbjct: 313 QQGPPPP--------PGPFPPRPPGPLGP-----------PLTLAP-PPHLPGPPPGAP- 351

Query: 189 AGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
               P    V     PPP   G+   + R PP
Sbjct: 352 ----PPAPHVNPAFFPPPTNSGMPTSDSRGPP 379



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 58/181 (32%), Positives = 63/181 (34%), Gaps = 21/181 (11%)

Query: 61  AGGLASSAATAQRGPSSSATLP-------RPPHHAP-----PGPAAGAPPPGCATLPRMP 108
           +G ++        G SS A  P       R P   P     PGPA    PP      + P
Sbjct: 177 SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTP 236

Query: 109 PDPYLQETRFEGPLPPPPPAAAAPPPPA-PAQTAQAPGFVVPTHAGTVGTLPLGGY---- 163
           P P L      GP  PPPP    PPP A P      P   V       G  PLG      
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296

Query: 164 --VAPGY-PLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPP 220
               PGY P    P     P  P G P+    PG  G   TL PPP  PG     P   P
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355

Query: 221 H 221
           H
Sbjct: 356 H 356



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/139 (30%), Positives = 44/139 (31%), Gaps = 34/139 (24%)

Query: 7   GLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLAS 66
           G P  VP   PPP   P PP + P PPP   P                  PR        
Sbjct: 295 GPPPPVPGYGPPP--GPPPPQQGPPPPPGPFP------------------PR-------- 326

Query: 67  SAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPP 126
                  GP    TL  PPH   PGP  GAPPP     P   P P            PPP
Sbjct: 327 --PPGPLGP--PLTLAPPPH--LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380

Query: 127 PAAAAPPPPAPAQTAQAPG 145
                 PPP        PG
Sbjct: 381 TDPYGRPPPYDRGDYGPPG 399


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 72/270 (26%), Positives = 91/270 (33%), Gaps = 70/270 (25%)

Query: 9   PDSVPHTSPPPYNAPQPPAEP-------PAPPPQAAPSSHHHHHHHYHQSGTATL----- 56
           P   P   PPP+ +P PP +P       P+ P  A P  H       H      L     
Sbjct: 254 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313

Query: 57  --------PRLGAGGLASSAATAQRGPSSSATLP---------RPPHHAPPGPAAGA--- 96
                   P+   G      + A   P +S  LP         +PP   P  PA  A   
Sbjct: 314 PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373

Query: 97  -PPPGCATLPRMP-PDPYLQETRFEGP--------LPPPP------------PAAAAPPP 134
             PP    +P++P P  +       GP        LPPPP            P +A PPP
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433

Query: 135 --------PAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGT 186
                   P P+  AQ PG    T +  +   P        + +  QP  A  P  P G 
Sbjct: 434 LQLMPQSQPLPSSPAQPPGL---TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 490

Query: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEP 216
           P    TP     TST   PP GPG +   P
Sbjct: 491 PPI--TPPTCPSTST---PPAGPGTSAQPP 515



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 78/282 (27%), Positives = 92/282 (32%), Gaps = 82/282 (29%)

Query: 15  TSPPPY---------NAPQPPAEP---------PAPPPQAAPSSHHHHHHHYHQSGTATL 56
           T+ PP          N PQ P  P         PA  PQ  PS H   H   H       
Sbjct: 217 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQ 273

Query: 57  PRLGAGGLASSAATAQ--------RGPSSSATLPRPPHHAPPGPAAGAPP---PGCATLP 105
           P  G+ G  S+ + AQ         GP S    P   H  PP P  G PP    G A L 
Sbjct: 274 PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQASQGQAPLG 332

Query: 106 RMPPDPY---------------LQETRFEGPLPP---------PPPAAAAPPPPAPAQTA 141
             P   Y                Q+   E PLPP         PPP    P  PAP    
Sbjct: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 392

Query: 142 QAPGFVVPTHAGTVGTLP----------LGGYVAPGY---PLQLQPCTAYVPVYPVGTPY 188
             P    P+       LP          L  +  P     PLQL P +  +P  P     
Sbjct: 393 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP----- 447

Query: 189 AGGTPGGTGVTSTLPPPPQG---PGLALLEPRRP--PHDYMP 225
               P G   +  LPPPP      GL  + P+ P   H ++P
Sbjct: 448 --AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 487



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/237 (28%), Positives = 81/237 (34%), Gaps = 49/237 (20%)

Query: 13  PHTSPPPYNAPQPPAEPPAPPP----QAAPSSHHHH----HHHYHQSGTATL-PRLGAGG 63
           P  SP    AP  P  P AP P    Q AP+ H       H   H S    L P  G+ G
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 280

Query: 64  LASSAATAQR--------GPSSSATLPRPPHHAPPGPAAGAPPP---GCATLPRMPPDPY 112
             S+ + AQ         GP S    P   H  PP P  G PP    G A L   P   Y
Sbjct: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAY 339

Query: 113 ----LQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGY 168
               LQ    +  L    P    P PPAP         +   H     T P+    AP  
Sbjct: 340 PHTSLQLPASQSALQSQQPPREQPLPPAP---------LAMPHIKPPPTTPIPQLPAP-- 388

Query: 169 PLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
                        +P   P+  G P    + + LPPPP    L+ L    PP  + P
Sbjct: 389 ---------QAHKHP---PHLSG-PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 432



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 49/175 (28%), Positives = 58/175 (33%), Gaps = 20/175 (11%)

Query: 11  SVPHTSPPPYNAPQPPAE---------PPAPPPQAAPSSHHHHHHHYHQ----SGTATLP 57
           S   +  PP   P PPA          P  P PQ      H H  H       S  A LP
Sbjct: 351 SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 410

Query: 58  RLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETR 117
              A    SS +T     +    L   P  + P P++ A PPG      +PP P      
Sbjct: 411 PPPALKPLSSLSTHHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469

Query: 118 FEGPLPPPPPAAAAP-----PPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG 167
               + P PP A  P     PPP    T  +     P   GT    P  G  A G
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS-TPPAGPGTSAQPPCSGAAASG 523



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 63/240 (26%), Positives = 82/240 (34%), Gaps = 55/240 (22%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGA 61
           S+++  L    P    P    P P + PP  P    P            S TA  P+   
Sbjct: 174 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPT--------PSATAVPPQ--- 222

Query: 62  GGLASSAATAQRGPSS--SATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFE 119
                 + TA + P+   + T P P  H    PA           P+ PP P+       
Sbjct: 223 -----GSPTASQAPNQPQAPTAPVPHTHIQQAPALH---------PQRPPSPH------- 261

Query: 120 GPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG-YPLQLQPCTAY 178
              PPP P   +P PP    T  A     P+HA      PL G   PG + LQ  P   +
Sbjct: 262 ---PPPHP---SPHPPLQPLTGSAGQPSAPSHAQP----PLHGQGPPGPHSLQAGPLLQH 311

Query: 179 V-PVYPVGTP---YAGGTPGGTGVTSTLP------PPPQGPGLALLEPRRPPHDYMPIAV 228
             P  P G P     G  P GT   +  P      P  Q    +   PR  P    P+A+
Sbjct: 312 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 371



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/160 (25%), Positives = 54/160 (33%), Gaps = 33/160 (20%)

Query: 13  PHTSPPPYNA-------PQPPAEPPA--------PPPQAAPSSHHHH--------HHHYH 49
           P   PPP          P  PA+PP         PPP + P +  H          H + 
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486

Query: 50  QSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPP 109
             G   +          S +T   GP +SA  P     A  G  AG        LP +  
Sbjct: 487 PGGPPPI----TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG---SSCPLPTVQI 539

Query: 110 DPYLQETRFEGPLPPPPPAAAAPPP---PAPAQTAQAPGF 146
                +   E   PPPPP + +P P     P+  +Q+  F
Sbjct: 540 KEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARF 579



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 14/110 (12%)

Query: 34  PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPA 93
           P     SH H H H HQ     L +  AG +         GP   A  P PP    P P 
Sbjct: 870 PHHHQHSHIHSHLHLHQQD--PLHQGSAGPVHPLVDPLTAGP-HLARFPYPP-GTLPNPL 925

Query: 94  AGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQA 143
            G PP              L+   F  P P   P  A PPP + A   QA
Sbjct: 926 LGQPP---------HEHEMLRHPVFGTPYPRDLP-GAIPPPMSAAHQLQA 965


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 72/270 (26%), Positives = 91/270 (33%), Gaps = 70/270 (25%)

Query: 9    PDSVPHTSPPPYNAPQPPAEP-------PAPPPQAAPSSHHHHHHHYHQSGTATL----- 56
            P   P   PPP+ +P PP +P       P+ P  A P  H       H      L     
Sbjct: 808  PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 57   --------PRLGAGGLASSAATAQRGPSSSATLP---------RPPHHAPPGPAAGA--- 96
                    P+   G      + A   P +S  LP         +PP   P  PA  A   
Sbjct: 868  PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 97   -PPPGCATLPRMP-PDPYLQETRFEGP--------LPPPP------------PAAAAPPP 134
              PP    +P++P P  +       GP        LPPPP            P +A PPP
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987

Query: 135  --------PAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGT 186
                    P P+  AQ PG    T +  +   P        + +  QP  A  P  P G 
Sbjct: 988  LQLMPQSQPLPSSPAQPPGL---TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044

Query: 187  PYAGGTPGGTGVTSTLPPPPQGPGLALLEP 216
            P    TP     TST   PP GPG +   P
Sbjct: 1045 PPI--TPPTCPSTST---PPAGPGTSAQPP 1069



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 78/282 (27%), Positives = 92/282 (32%), Gaps = 82/282 (29%)

Query: 15   TSPPPY---------NAPQPPAEP---------PAPPPQAAPSSHHHHHHHYHQSGTATL 56
            T+ PP          N PQ P  P         PA  PQ  PS H   H   H       
Sbjct: 771  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQ 827

Query: 57   PRLGAGGLASSAATAQ--------RGPSSSATLPRPPHHAPPGPAAGAPP---PGCATLP 105
            P  G+ G  S+ + AQ         GP S    P   H  PP P  G PP    G A L 
Sbjct: 828  PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQASQGQAPLG 886

Query: 106  RMPPDPY---------------LQETRFEGPLPP---------PPPAAAAPPPPAPAQTA 141
              P   Y                Q+   E PLPP         PPP    P  PAP    
Sbjct: 887  TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 142  QAPGFVVPTHAGTVGTLP----------LGGYVAPGY---PLQLQPCTAYVPVYPVGTPY 188
              P    P+       LP          L  +  P     PLQL P +  +P  P     
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP----- 1001

Query: 189  AGGTPGGTGVTSTLPPPPQG---PGLALLEPRRP--PHDYMP 225
                P G   +  LPPPP      GL  + P+ P   H ++P
Sbjct: 1002 --AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/237 (28%), Positives = 81/237 (34%), Gaps = 49/237 (20%)

Query: 13  PHTSPPPYNAPQPPAEPPAPPP----QAAPSSHHHH----HHHYHQSGTATL-PRLGAGG 63
           P  SP    AP  P  P AP P    Q AP+ H       H   H S    L P  G+ G
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 834

Query: 64  LASSAATAQR--------GPSSSATLPRPPHHAPPGPAAGAPPP---GCATLPRMPPDPY 112
             S+ + AQ         GP S    P   H  PP P  G PP    G A L   P   Y
Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAY 893

Query: 113 ----LQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGY 168
               LQ    +  L    P    P PPAP         +   H     T P+    AP  
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAP---------LAMPHIKPPPTTPIPQLPAP-- 942

Query: 169 PLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
                        +P   P+  G P    + + LPPPP    L+ L    PP  + P
Sbjct: 943 ---------QAHKHP---PHLSG-PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 49/175 (28%), Positives = 58/175 (33%), Gaps = 20/175 (11%)

Query: 11   SVPHTSPPPYNAPQPPAE---------PPAPPPQAAPSSHHHHHHHYHQ----SGTATLP 57
            S   +  PP   P PPA          P  P PQ      H H  H       S  A LP
Sbjct: 905  SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 964

Query: 58   RLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETR 117
               A    SS +T     +    L   P  + P P++ A PPG      +PP P      
Sbjct: 965  PPPALKPLSSLSTHHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023

Query: 118  FEGPLPPPPPAAAAP-----PPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG 167
                + P PP A  P     PPP    T  +     P   GT    P  G  A G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS-TPPAGPGTSAQPPCSGAAASG 1077



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 63/240 (26%), Positives = 82/240 (34%), Gaps = 55/240 (22%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGA 61
           S+++  L    P    P    P P + PP  P    P            S TA  P+   
Sbjct: 728 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPT--------PSATAVPPQ--- 776

Query: 62  GGLASSAATAQRGPSS--SATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFE 119
                 + TA + P+   + T P P  H    PA           P+ PP P+       
Sbjct: 777 -----GSPTASQAPNQPQAPTAPVPHTHIQQAPALH---------PQRPPSPH------- 815

Query: 120 GPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG-YPLQLQPCTAY 178
              PPP P   +P PP    T  A     P+HA      PL G   PG + LQ  P   +
Sbjct: 816 ---PPPHP---SPHPPLQPLTGSAGQPSAPSHAQP----PLHGQGPPGPHSLQAGPLLQH 865

Query: 179 V-PVYPVGTP---YAGGTPGGTGVTSTLP------PPPQGPGLALLEPRRPPHDYMPIAV 228
             P  P G P     G  P GT   +  P      P  Q    +   PR  P    P+A+
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 925



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/160 (25%), Positives = 54/160 (33%), Gaps = 33/160 (20%)

Query: 13   PHTSPPPYNA-------PQPPAEPPA--------PPPQAAPSSHHHH--------HHHYH 49
            P   PPP          P  PA+PP         PPP + P +  H          H + 
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 50   QSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPP 109
              G   +          S +T   GP +SA  P     A  G  AG        LP +  
Sbjct: 1041 PGGPPPI----TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG---SSCPLPTVQI 1093

Query: 110  DPYLQETRFEGPLPPPPPAAAAPPP---PAPAQTAQAPGF 146
                 +   E   PPPPP + +P P     P+  +Q+  F
Sbjct: 1094 KEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARF 1133



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 14/110 (12%)

Query: 34   PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPA 93
            P     SH H H H HQ     L +  AG +         GP   A  P PP    P P 
Sbjct: 1424 PHHHQHSHIHSHLHLHQQD--PLHQGSAGPVHPLVDPLTAGP-HLARFPYPP-GTLPNPL 1479

Query: 94   AGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQA 143
             G PP              L+   F  P P   P  A PPP + A   QA
Sbjct: 1480 LGQPP---------HEHEMLRHPVFGTPYPRDLP-GAIPPPMSAAHQLQA 1519


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 72/270 (26%), Positives = 91/270 (33%), Gaps = 70/270 (25%)

Query: 9    PDSVPHTSPPPYNAPQPPAEP-------PAPPPQAAPSSHHHHHHHYHQSGTATL----- 56
            P   P   PPP+ +P PP +P       P+ P  A P  H       H      L     
Sbjct: 808  PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867

Query: 57   --------PRLGAGGLASSAATAQRGPSSSATLP---------RPPHHAPPGPAAGA--- 96
                    P+   G      + A   P +S  LP         +PP   P  PA  A   
Sbjct: 868  PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 97   -PPPGCATLPRMP-PDPYLQETRFEGP--------LPPPP------------PAAAAPPP 134
              PP    +P++P P  +       GP        LPPPP            P +A PPP
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987

Query: 135  --------PAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGT 186
                    P P+  AQ PG    T +  +   P        + +  QP  A  P  P G 
Sbjct: 988  LQLMPQSQPLPSSPAQPPGL---TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP 1044

Query: 187  PYAGGTPGGTGVTSTLPPPPQGPGLALLEP 216
            P    TP     TST   PP GPG +   P
Sbjct: 1045 PPI--TPPTCPSTST---PPAGPGTSAQPP 1069



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 78/282 (27%), Positives = 92/282 (32%), Gaps = 82/282 (29%)

Query: 15   TSPPPY---------NAPQPPAEP---------PAPPPQAAPSSHHHHHHHYHQSGTATL 56
            T+ PP          N PQ P  P         PA  PQ  PS H   H   H       
Sbjct: 771  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQ 827

Query: 57   PRLGAGGLASSAATAQ--------RGPSSSATLPRPPHHAPPGPAAGAPP---PGCATLP 105
            P  G+ G  S+ + AQ         GP S    P   H  PP P  G PP    G A L 
Sbjct: 828  PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQASQGQAPLG 886

Query: 106  RMPPDPY---------------LQETRFEGPLPP---------PPPAAAAPPPPAPAQTA 141
              P   Y                Q+   E PLPP         PPP    P  PAP    
Sbjct: 887  TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 142  QAPGFVVPTHAGTVGTLP----------LGGYVAPGY---PLQLQPCTAYVPVYPVGTPY 188
              P    P+       LP          L  +  P     PLQL P +  +P  P     
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP----- 1001

Query: 189  AGGTPGGTGVTSTLPPPPQG---PGLALLEPRRP--PHDYMP 225
                P G   +  LPPPP      GL  + P+ P   H ++P
Sbjct: 1002 --AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 68/237 (28%), Positives = 81/237 (34%), Gaps = 49/237 (20%)

Query: 13  PHTSPPPYNAPQPPAEPPAPPP----QAAPSSHHHH----HHHYHQSGTATL-PRLGAGG 63
           P  SP    AP  P  P AP P    Q AP+ H       H   H S    L P  G+ G
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 834

Query: 64  LASSAATAQR--------GPSSSATLPRPPHHAPPGPAAGAPPP---GCATLPRMPPDPY 112
             S+ + AQ         GP S    P   H  PP P  G PP    G A L   P   Y
Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAY 893

Query: 113 ----LQETRFEGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGY 168
               LQ    +  L    P    P PPAP         +   H     T P+    AP  
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAP---------LAMPHIKPPPTTPIPQLPAP-- 942

Query: 169 PLQLQPCTAYVPVYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
                        +P   P+  G P    + + LPPPP    L+ L    PP  + P
Sbjct: 943 ---------QAHKHP---PHLSG-PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 49/175 (28%), Positives = 58/175 (33%), Gaps = 20/175 (11%)

Query: 11   SVPHTSPPPYNAPQPPAE---------PPAPPPQAAPSSHHHHHHHYHQ----SGTATLP 57
            S   +  PP   P PPA          P  P PQ      H H  H       S  A LP
Sbjct: 905  SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP 964

Query: 58   RLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETR 117
               A    SS +T     +    L   P  + P P++ A PPG      +PP P      
Sbjct: 965  PPPALKPLSSLSTHHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023

Query: 118  FEGPLPPPPPAAAAP-----PPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG 167
                + P PP A  P     PPP    T  +     P   GT    P  G  A G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS-TPPAGPGTSAQPPCSGAAASG 1077



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 63/240 (26%), Positives = 82/240 (34%), Gaps = 55/240 (22%)

Query: 2   SSEKSGLPDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGA 61
           S+++  L    P    P    P P + PP  P    P            S TA  P+   
Sbjct: 728 SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPT--------PSATAVPPQ--- 776

Query: 62  GGLASSAATAQRGPSS--SATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFE 119
                 + TA + P+   + T P P  H    PA           P+ PP P+       
Sbjct: 777 -----GSPTASQAPNQPQAPTAPVPHTHIQQAPALH---------PQRPPSPH------- 815

Query: 120 GPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPG-YPLQLQPCTAY 178
              PPP P   +P PP    T  A     P+HA      PL G   PG + LQ  P   +
Sbjct: 816 ---PPPHP---SPHPPLQPLTGSAGQPSAPSHAQP----PLHGQGPPGPHSLQAGPLLQH 865

Query: 179 V-PVYPVGTP---YAGGTPGGTGVTSTLP------PPPQGPGLALLEPRRPPHDYMPIAV 228
             P  P G P     G  P GT   +  P      P  Q    +   PR  P    P+A+
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 925



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/160 (25%), Positives = 54/160 (33%), Gaps = 33/160 (20%)

Query: 13   PHTSPPPYNA-------PQPPAEPPA--------PPPQAAPSSHHHH--------HHHYH 49
            P   PPP          P  PA+PP         PPP + P +  H          H + 
Sbjct: 981  PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040

Query: 50   QSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPP 109
              G   +          S +T   GP +SA  P     A  G  AG        LP +  
Sbjct: 1041 PGGPPPI----TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG---SSCPLPTVQI 1093

Query: 110  DPYLQETRFEGPLPPPPPAAAAPPP---PAPAQTAQAPGF 146
                 +   E   PPPPP + +P P     P+  +Q+  F
Sbjct: 1094 KEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARF 1133



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 14/110 (12%)

Query: 34   PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPA 93
            P     SH H H H HQ     L +  AG +         GP   A  P PP    P P 
Sbjct: 1424 PHHHQHSHIHSHLHLHQQD--PLHQGSAGPVHPLVDPLTAGP-HLARFPYPP-GTLPNPL 1479

Query: 94   AGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAQTAQA 143
             G PP              L+   F  P P   P  A PPP + A   QA
Sbjct: 1480 LGQPP---------HEHEMLRHPVFGTPYPRDLP-GAIPPPMSAAHQLQA 1519


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 49/137 (35%), Positives = 55/137 (40%), Gaps = 24/137 (17%)

Query: 9   PDSVPHTSPPPYNAPQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLAS-- 66
           P   P  +P    A  PP  P APPP  AP +          +  A  PR  A    +  
Sbjct: 111 PPRAPRGAPAAAAAAAPPPTP-APPPPPAPVA---------AAAPARAPRAAAAAATAPP 160

Query: 67  SAATAQRGPSSSATLP-RPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPP 125
           S   AQ GP +    P   P  AP  P A APP G    PR  P P +     E PLPPP
Sbjct: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG----PRRAPPPAVAAR--EPPLPPP 214

Query: 126 -----PPAAAAPPPPAP 137
                PP    PPPP P
Sbjct: 215 PQPPAPPQQQQPPPPQP 231



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 51/169 (30%), Positives = 55/169 (32%), Gaps = 28/169 (16%)

Query: 62  GGLASSAATAQRGPSSSATLPRPPHH---APPGPAAGAPPPGCATLPRMPPDPYLQETRF 118
           G ++   A   + P   AT P PP     AP   AA APPP                   
Sbjct: 89  GSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPT------------------ 130

Query: 119 EGPLPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAY 178
             P PPPPPA  A   PA A  A A     P   G     P     A   PL   P    
Sbjct: 131 --PAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA---PLAAPPPAPA 185

Query: 179 VP--VYPVGTPYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMP 225
            P  V P   P     P        LPPPPQ P     +   PP    P
Sbjct: 186 APPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 50/150 (33%), Positives = 63/150 (42%), Gaps = 28/150 (18%)

Query: 11  SVPHTSPPPYNAPQPPAEPPAPP--PQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68
           S+ + +      P+  A PPAPP  P+ AP++            T   P   A   A++ 
Sbjct: 90  SISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAA----PPPTPAPPPPPAPVAAAAP 145

Query: 69  ATAQRGPSSSATLPRPPHHAPPGPAA------GAPPPGCATLPRMPPDPYLQETRFEGP- 121
           A A R  +++AT P  P  A PGP A       APPP  A  P + P          GP 
Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPA--------GPR 197

Query: 122 -LPPPPPAAAAPP------PPAPAQTAQAP 144
             PPP  AA  PP      PPAP Q  Q P
Sbjct: 198 RAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 11/22 (50%), Positives = 12/22 (54%)

Query: 17  PPPYNAPQPPAEPPAPPPQAAP 38
           PPP   P PP +   PPPQ  P
Sbjct: 212 PPPPQPPAPPQQQQPPPPQPQP 233



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%)

Query: 51  SGTATLPRLGAGGLASSAATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCAT-LPRMPP 109
           SGT  +  + A       A+   GP S + +P PP   P  P A   P GC       P 
Sbjct: 399 SGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPP-GKPALPGADGTPFGCPPGRKEKPS 457

Query: 110 DP 111
           DP
Sbjct: 458 DP 459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,802,949
Number of Sequences: 37866
Number of extensions: 1612115
Number of successful extensions: 52794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 927
Number of HSP's successfully gapped in prelim test: 1901
Number of HSP's that attempted gapping in prelim test: 15084
Number of HSP's gapped (non-prelim): 18269
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press