Guide to the Human Genome
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Name: WWOX Sequence: fasta or formatted (414aa) NCBI GI: 7706523
Description:

WW domain-containing oxidoreductase isoform 1

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Gene Structure
WW Domain

Other entries for this name:
alt prot [189aa] WW domain-containing oxidoreductase isoform 2
alt prot [36aa] WW domain-containing oxidoreductase isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.9         37           2
 C cysteine            1.9          8           2
 D aspartate           4.8         20           2
 E glutamate           6.5         27           2
 F phenylalanine       4.1         17           2
 G glycine             6.0         25           2
 H histidine           3.4         14           1
 I isoleucine          2.4         10           1
 K lysine              4.3         18           1
 L leucine             9.9         41           2
 M methionine          2.4         10           2
 N asparagine          4.6         19           2
 P proline             4.1         17           2
 Q glutamine           3.4         14           2
 R arginine            6.5         27           2
 S serine              6.5         27           2
 T threonine           8.0         33           2
 V valine              6.5         27           4
 W tryptophan          2.4         10           2
 Y tyrosine            3.1         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   WW domain-containing oxidoreductase isoform 1 
WWOX                  0.406   WW domain-containing oxidoreductase isoform 2 
RDH12                 0.226   retinol dehydrogenase 12 
RDH11                 0.207   retinol dehydrogenase 11 
RDH14                 0.202   retinol dehydrogenase 14 (all-trans and 9-cis) [Homo...
RDH13                 0.196   retinol dehydrogenase 13 isoform 1 
DHRSX                 0.168   dehydrogenase/reductase (SDR family) X-linked [Homo...
DHRS13                0.167   dehydrogenase/reductase (SDR family) member 13 [Hom...
RDH13                 0.147   retinol dehydrogenase 13 isoform 2 
HSD17B7               0.068   hydroxysteroid (17-beta) dehydrogenase 7 
WWOX                  0.066   WW domain-containing oxidoreductase isoform 3 
ITCH                  0.063   itchy homolog E3 ubiquitin protein ligase 
WWP2                  0.059   WW domain containing E3 ubiquitin protein ligase 2 i...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally dow...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
NEDD4L                0.053   neural precursor cell expressed, developmentally do...
WWP1                  0.053   WW domain containing E3 ubiquitin protein ligase 1 [...
YAP1                  0.052   Yes-associated protein 1, 65kDa isoform 1 
MAGI2                 0.051   membrane associated guanylate kinase, WW and PDZ dom...
WWC2                  0.048   WW and C2 domain containing 2 
NEDD4                 0.048   neural precursor cell expressed, developmentally do...
NEDD4                 0.048   neural precursor cell expressed, developmentally do...
SMURF2                0.046   SMAD specific E3 ubiquitin protein ligase 2 
SMURF1                0.045   Smad ubiquitination regulatory factor 1 isoform 2 [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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