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Search of human proteins with 14141166
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
(362 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 715 0.0
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 709 0.0
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 709 0.0
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 703 0.0
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 632 0.0
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 627 e-180
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 595 e-170
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 565 e-161
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 487 e-138
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 414 e-116
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 350 9e-97
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 350 9e-97
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 266 2e-71
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 155 7e-38
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 154 1e-37
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 154 1e-37
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 106 3e-23
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 102 4e-22
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 81 2e-15
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 78 1e-14
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 76 5e-14
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 73 3e-13
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 70 2e-12
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 70 2e-12
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 70 2e-12
gi|122937472 bicaudal C homolog 1 [Homo sapiens] 57 3e-08
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 55 1e-07
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 55 1e-07
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 715 bits (1845), Expect = 0.0
Identities = 362/362 (100%), Positives = 362/362 (100%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
Query: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
Query: 361 SS 362
SS
Sbjct: 361 SS 362
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 709 bits (1830), Expect = 0.0
Identities = 362/366 (98%), Positives = 362/366 (98%), Gaps = 4/366 (1%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 236
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 237 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 296
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 300
Query: 297 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 356
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 301 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 360
Query: 357 GGMGSS 362
GGMGSS
Sbjct: 361 GGMGSS 366
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 709 bits (1829), Expect = 0.0
Identities = 361/362 (99%), Positives = 361/362 (99%), Gaps = 1/362 (0%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Query: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLIGCII
Sbjct: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLIGCII 299
Query: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 300 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 359
Query: 361 SS 362
SS
Sbjct: 360 SS 361
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 703 bits (1814), Expect = 0.0
Identities = 361/366 (98%), Positives = 361/366 (98%), Gaps = 5/366 (1%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 236
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 237 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 296
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
Query: 297 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 356
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
Query: 357 GGMGSS 362
GGMGSS
Sbjct: 360 GGMGSS 365
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 632 bits (1631), Expect = 0.0
Identities = 331/362 (91%), Positives = 331/362 (91%), Gaps = 31/362 (8%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
Query: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII
Sbjct: 210 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 269
Query: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 270 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 329
Query: 361 SS 362
SS
Sbjct: 330 SS 331
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 627 bits (1616), Expect = e-180
Identities = 331/366 (90%), Positives = 331/366 (90%), Gaps = 35/366 (9%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 236
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 209
Query: 237 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 296
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI
Sbjct: 210 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 269
Query: 297 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 356
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 270 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 329
Query: 357 GGMGSS 362
GGMGSS
Sbjct: 330 GGMGSS 335
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 595 bits (1535), Expect = e-170
Identities = 318/362 (87%), Positives = 318/362 (87%), Gaps = 44/362 (12%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
KPSSSPVIFAGGQ AYTIQGQYAIPQPDLT
Sbjct: 181 KPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQPDLT 209
Query: 241 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCII 300
KLHQLAMQQSHFPMTHGNTGFS AGLDASAQTTSHELTIPNDLIGCII
Sbjct: 210 KLHQLAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLIGCII 256
Query: 301 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 360
GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG
Sbjct: 257 GRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMG 316
Query: 361 SS 362
SS
Sbjct: 317 SS 318
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 565 bits (1455), Expect = e-161
Identities = 300/367 (81%), Positives = 323/367 (88%), Gaps = 16/367 (4%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175
KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 176 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235
IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I
Sbjct: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231
Query: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDL 295
DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+L
Sbjct: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290
Query: 296 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 355
IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE
Sbjct: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350
Query: 356 TGGMGSS 362
GMG S
Sbjct: 351 K-GMGCS 356
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 487 bits (1254), Expect = e-138
Identities = 263/369 (71%), Positives = 293/369 (79%), Gaps = 39/369 (10%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPD-L 239
KP+S+PVIFAGGQ AYTIQGQYAIP PD L
Sbjct: 213 KPASTPVIFAGGQ-------------------------------AYTIQGQYAIPHPDQL 241
Query: 240 TKLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHELTIP 292
TKLHQLAMQQ+ F P+ N F G + SS + + G +GLDAS ++HELTIP
Sbjct: 242 TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIP 301
Query: 293 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL 352
NDLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN RL
Sbjct: 302 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 361
Query: 353 SSETGGMGS 361
+SE GMG+
Sbjct: 362 TSEVTGMGT 370
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 414 bits (1063), Expect = e-116
Identities = 236/368 (64%), Positives = 267/368 (72%), Gaps = 63/368 (17%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE+ TI
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEA----YTI---- 204
Query: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 240
Q +Y + PH PDLT
Sbjct: 205 ------------QGQY-------AIPH-----------------------------PDLT 216
Query: 241 KLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHELTIPN 293
KLHQLAMQQ+ F P+ N F G + SS + + G +GLDAS ++HELTIPN
Sbjct: 217 KLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPN 276
Query: 294 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLS 353
DLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN RL+
Sbjct: 277 DLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLT 336
Query: 354 SETGGMGS 361
SE GMG+
Sbjct: 337 SEVTGMGT 344
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 350 bits (899), Expect = 9e-97
Identities = 195/360 (54%), Positives = 242/360 (67%), Gaps = 52/360 (14%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTKLHQL 245
V+ + Q +++QGQY A+ ++TKL QL
Sbjct: 191 VLLSANQ-------------------------------GFSVQGQYGAVTPAEVTKLQQL 219
Query: 246 AMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGA 305
+ SH + ++P V GLD QT+S E +PNDLIGC+IGRQG+
Sbjct: 220 S---SH-----------AVPFATPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQGS 262
Query: 306 KINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGMGSS 362
KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 263 KISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 322
Score = 65.9 bits (159), Expect = 6e-11
Identities = 68/283 (24%), Positives = 114/283 (40%), Gaps = 70/283 (24%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 71 AFAMI----------------------------------------------IDKLEEDIS 84
I + KL++ S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
Query: 138 LPNSTERAITIAGIPQSI----------IECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+ ER +TI G P SI +E K S P + P+ P ++ P
Sbjct: 281 AEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPT 340
Query: 188 IFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 227
G Y+ + P + L P GPP L AYT
Sbjct: 341 APPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 350 bits (899), Expect = 9e-97
Identities = 195/360 (54%), Positives = 242/360 (67%), Gaps = 52/360 (14%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LESPPKG TIPY P S
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190
Query: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTKLHQL 245
V+ + Q +++QGQY A+ ++TKL QL
Sbjct: 191 VLLSANQ-------------------------------GFSVQGQYGAVTPAEVTKLQQL 219
Query: 246 AMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGA 305
+ SH + ++P V GLD QT+S E +PNDLIGC+IGRQG+
Sbjct: 220 S---SH-----------AVPFATPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQGS 262
Query: 306 KINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGMGSS 362
KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG SS
Sbjct: 263 KISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSS 322
Score = 65.9 bits (159), Expect = 6e-11
Identities = 68/283 (24%), Positives = 114/283 (40%), Gaps = 70/283 (24%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 71 AFAMI----------------------------------------------IDKLEEDIS 84
I + KL++ S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
Query: 138 LPNSTERAITIAGIPQSI----------IECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+ ER +TI G P SI +E K S P + P+ P ++ P
Sbjct: 281 AEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPT 340
Query: 188 IFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 227
G Y+ + P + L P GPP L AYT
Sbjct: 341 APPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 266 bits (681), Expect = 2e-71
Identities = 167/380 (43%), Positives = 209/380 (55%), Gaps = 107/380 (28%)
Query: 42 ESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLR 101
+S ARI ISEG+CPERI T+ G T A+F A +MI KL+ED+ ++ N SRPPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 102 LVVPASQCGSLIGKGGCKIK---EIR---------------------------------- 124
LV+PASQCGSLIGK G KIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 125 ------------------ESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVM 166
++TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 167 LESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY 226
LESPPKG TIPY P S V+ + Q +
Sbjct: 192 LESPPKGATIPYHPSLSLGTVLLSANQ-------------------------------GF 220
Query: 227 TIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTT 285
++QGQY A+ ++TKL QL+ SH + ++P V GLD QT+
Sbjct: 221 SVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVV---PGLDPGTQTS 263
Query: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQ
Sbjct: 264 SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQ 323
Query: 346 YLINVRL---SSETGGMGSS 362
YLI L S +GG SS
Sbjct: 324 YLITACLETAKSTSGGTPSS 343
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 14/138 (10%)
Query: 103 VVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSI------- 155
+VP G +IG+ G KI EIR+ +GA +++ G+ + ER +TI G P SI
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIALAQYLI 326
Query: 156 ---IECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDR-YSTGSDSASFPHTTPS 211
+E K S P + P+ P ++ P G Y+ + P
Sbjct: 327 TACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMPF 386
Query: 212 MCLNPDLEGPP--LEAYT 227
+ L P GPP L AYT
Sbjct: 387 LALPPASPGPPPGLAAYT 404
Score = 35.4 bits (80), Expect = 0.080
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 25 VGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
+G +IG++G + ++R+ SGA I I +EG ER +T+ G +I A +I LE
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332
Query: 82 DISSSMTNSTAAS-------RPPVTLRLVVPASQCGS 111
S+S ++A PP+T P G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 155 bits (391), Expect = 7e-38
Identities = 121/420 (28%), Positives = 183/420 (43%), Gaps = 82/420 (19%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209
PY P +P P+ GG DR G P +
Sbjct: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
Query: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237
S N L PP L AY G
Sbjct: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
Query: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIG 297
+ S + M + G SG + S +G + L TT ++TIP DL G
Sbjct: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAG 400
Query: 298 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 357
IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ + +G
Sbjct: 401 SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSG 460
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+K+I + E G+ +P S P+
Sbjct: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 154 bits (389), Expect = 1e-37
Identities = 120/411 (29%), Positives = 180/411 (43%), Gaps = 82/411 (19%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209
PY P +P P+ GG DR G P +
Sbjct: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
Query: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237
S N L PP L AY G
Sbjct: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
Query: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIG 297
+ S + M + G SG + S +G + L TT ++TIP DL G
Sbjct: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAG 400
Query: 298 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 348
IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 401 SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+K+I + E G+ +P S P+
Sbjct: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 154 bits (389), Expect = 1e-37
Identities = 120/411 (29%), Positives = 180/411 (43%), Gaps = 82/411 (19%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVT 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K I ++ ESP KG
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222
Query: 176 IPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT----- 209
PY P +P P+ GG DR G P +
Sbjct: 223 QPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDD 282
Query: 210 ------------------PSMCLNPDLEGPP------LEAY--------TIQGQYAIPQP 237
S N L PP L AY G
Sbjct: 283 MSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSAD 342
Query: 238 DLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIG 297
+ S + M + G SG + S +G + L TT ++TIP DL G
Sbjct: 343 ETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT--QVTIPKDLAG 400
Query: 298 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 348
IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 401 SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+K+I + E G+ +P S P+
Sbjct: 100 ILKKIIPTLEE----GLQLPSPTATSQLPL 125
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 106 bits (265), Expect = 3e-23
Identities = 108/423 (25%), Positives = 185/423 (43%), Gaps = 82/423 (19%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
Query: 122 EIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTIP 177
+ E +GA VQ++ D + N ER +T++G P+ + V+ I + E P G + I
Sbjct: 172 AVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNIS 230
Query: 178 Y--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------- 206
Y P+ SP A G ++ + A+FP
Sbjct: 231 YANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVA 290
Query: 207 -----HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM--- 254
+T S N + G L G A P + LA S
Sbjct: 291 ITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGS 350
Query: 255 ----THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIPNDLIG 297
T G + +++ GY+ L ASA + E+ +P +L+G
Sbjct: 351 TAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVG 410
Query: 298 CIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLSS 354
I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI R++
Sbjct: 411 AILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITY 470
Query: 355 ETG 357
E G
Sbjct: 471 EQG 473
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 102 bits (255), Expect = 4e-22
Identities = 110/447 (24%), Positives = 188/447 (42%), Gaps = 106/447 (23%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
I +K+ E + SS T + ++ P+T
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSI 155
++++VP S G +IGKGG +K + E +GA VQ++ D + N ER +T++G P+
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQN 230
Query: 156 IECVKQICVVMLESPPKG--VTIPY--------RPKPSSSP----------VIFAGGQDR 195
+ V+ I + E P G + I Y P+ SP A G
Sbjct: 231 RKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLG 290
Query: 196 YSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQYAI--- 234
++ + A+FP +T S N + G L G A
Sbjct: 291 HANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAA 350
Query: 235 -PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWAG---LDASAQ 283
P + LA S T G + +++ GY+ L ASA
Sbjct: 351 SANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAI 410
Query: 284 TTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDR 330
+ E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+ +R
Sbjct: 411 LGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNR 470
Query: 331 QVTITGSAASISLAQYLINVRLSSETG 357
+VTITG+ A+ AQYLI R++ E G
Sbjct: 471 KVTITGTPAATQAAQYLITQRITYEQG 497
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 80.9 bits (198), Expect = 2e-15
Identities = 88/369 (23%), Positives = 154/369 (41%), Gaps = 57/369 (15%)
Query: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
Query: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPP---KGVTIPYR-------- 179
V + LP ++ + I G + + + + ++ E +GV +
Sbjct: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSI 256
Query: 180 ----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 257 EVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG----- 305
Query: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKG---YWAGLDASAQTTSHELTIP 292
PD + H + GF G+ ++ +G + G Q ++ T+P
Sbjct: 306 PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITY--TVP 362
Query: 293 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLIN 349
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 363 ADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLID 422
Query: 350 VRLSSETGG 358
++ G
Sbjct: 423 EKVGGTNLG 431
Score = 75.9 bits (185), Expect = 5e-14
Identities = 75/249 (30%), Positives = 106/249 (42%), Gaps = 29/249 (11%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
Query: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
+GA V++ + PNS R TI G+PQ IE +Q+ + G + P S
Sbjct: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFS 442
Query: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQPDLTK 241
P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 443 QPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQAWQQP 498
Query: 242 LHQLAMQQS 250
Q+ QQS
Sbjct: 499 TQQVPSQQS 507
Score = 49.3 bits (116), Expect = 5e-06
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 131 VQVAGDMLPNSTERAITIAGIP 152
+Q D S ERA + G P
Sbjct: 287 IQFKPDD-GISPERAAQVMGPP 307
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
Query: 346 YLI 348
L+
Sbjct: 139 RLL 141
Score = 38.5 bits (88), Expect = 0.009
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
Query: 155 I 155
I
Sbjct: 134 I 134
Score = 33.9 bits (76), Expect = 0.23
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 265 ESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 324
E + +G ++ S E+++P +G +IGR G I +I+ +G +I+ P
Sbjct: 234 EKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPD 292
Query: 325 EG-STDRQVTITGSAASISLAQYLIN--VRLSSETGGMG 360
+G S +R + G A ++I+ + + E G G
Sbjct: 293 DGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFG 331
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 77.8 bits (190), Expect = 1e-14
Identities = 81/313 (25%), Positives = 133/313 (42%), Gaps = 34/313 (10%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 71 AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120
+ I +K+ E I +MT + +P T+ +L+VP S G +IGKGG +
Sbjct: 95 VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
Query: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
K + E +GA VQ++ P N ER +T++G P+ + + V I + E P +
Sbjct: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLN 211
Query: 178 YRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTP-----SMCLNPDLEGPPLEAYTIQGQY 232
+ PV + TGS AS P S L GP A
Sbjct: 212 ISYANVAGPV-----ANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPA 266
Query: 233 AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIP 292
A+P T L ++ + NT G+ +S G A + A A +
Sbjct: 267 ALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVAAGANPAA---AAA 323
Query: 293 NDLIGCIIGRQGA 305
+L+ G GA
Sbjct: 324 ANLLASYAGEAGA 336
Score = 60.8 bits (146), Expect = 2e-09
Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 344
E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ +R+VTITGS A+ A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 345 QYLINVRLSSETGGMGSS 362
QYLI+ R++ E G S+
Sbjct: 470 QYLISQRVTYEQGVRASN 487
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 92 AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149
AA + + VP + G+++GKGG + E +E TGA++Q++ G+ LP + R +TI
Sbjct: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
Query: 150 GIP 152
G P
Sbjct: 461 GSP 463
Score = 39.3 bits (90), Expect = 0.006
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 344
+L +PN G IIG+ GA + + + SGA ++++ EG +R VT++G + A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
Score = 33.5 bits (75), Expect = 0.30
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 344
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R + G+A +++
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 345 QYLI 348
I
Sbjct: 96 HSFI 99
Score = 29.6 bits (65), Expect = 4.4
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE 51
VG+I+GK G+++ + +E +GARI IS+
Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 75.9 bits (185), Expect = 5e-14
Identities = 84/353 (23%), Positives = 147/353 (41%), Gaps = 38/353 (10%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D +
Sbjct: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
Query: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139
++ + +++PA + G +IGKGG IK+++E G ++ + D
Sbjct: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
Query: 140 N-STERAITIAGIPQSIIECVKQICVVMLESPP--------------KGVTIPYRPKPSS 184
N + ++ + I G P + + + + ++ E G+ +P P+ S
Sbjct: 276 NTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-PRHSV 334
Query: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQ 244
VI G+ +D+ D GP A+ I G PD +
Sbjct: 335 GVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAH-IMG-----PPDRCEHAA 383
Query: 245 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELT--IPNDLIGCIIGR 302
+ + G G G P +G G + E+T IP G +IGR
Sbjct: 384 RIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRG-QGNWGPPGGEMTFSIPTHKCGLVIGR 442
Query: 303 QGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 352
G + I Q +GA ++I+ + + D + I GS I A+ LI ++
Sbjct: 443 GGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 33/226 (14%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+
Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
Query: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126
S PP + +P +CG +IG+GG +K I +
Sbjct: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSS 184
TGA V+++ + PN + I G PQ I+ KQ ++E +G P P P
Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQ----LIEEKIEGPLCPVGPGPGG 508
Query: 185 SPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 230
AG ++ G + P P GPP Y QG
Sbjct: 509 PGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
Score = 53.5 bits (127), Expect = 3e-07
Identities = 52/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (6%)
Query: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63
GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G
Sbjct: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
Query: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122
+ +A M++D L E D + SR + + VP G +IG+ G IK+
Sbjct: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
Query: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKP 182
I+ G ++Q D E+ I G P E +I +L+S G P P
Sbjct: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSG-----PPGP 400
Query: 183 SSSPVIFAGGQDR 195
P + GG+ R
Sbjct: 401 PGGPGMPPGGRGR 413
Score = 53.1 bits (126), Expect = 4e-07
Identities = 25/73 (34%), Positives = 47/73 (64%)
Query: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 345
+ E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+
Sbjct: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
Query: 346 YLINVRLSSETGG 358
+++ +S GG
Sbjct: 206 MMLDDIVSRGRGG 218
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Query: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138
+ ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
Query: 139 PNSTERAITIAGIPQSI 155
P ER++++ G P+S+
Sbjct: 188 P---ERSVSLTGAPESV 201
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/71 (25%), Positives = 31/71 (43%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 347
++ +P +G +IGR G I +I+ +G +I+ ++ I G A +
Sbjct: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 348 INVRLSSETGG 358
IN L S G
Sbjct: 386 INDLLQSLRSG 396
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 502 VPRDQTPDENEEVI 515
Score = 68.9 bits (167), Expect = 7e-12
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 26/167 (15%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
Query: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
A I+ KL E + M T+S S + L +P
Sbjct: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
Query: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
Score = 61.2 bits (147), Expect = 1e-09
Identities = 67/266 (25%), Positives = 111/266 (41%), Gaps = 15/266 (5%)
Query: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
Query: 160 KQICVVMLESPPK---GVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP 216
+ I +M + + IP + + V G++ G + H T +
Sbjct: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITIS 311
Query: 217 DLEG----PPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 272
L+ P T++G ++ + + M NT S P +
Sbjct: 312 SLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQ 371
Query: 273 -GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TD 329
G + + + L IP +G IIG++GA I ++ + +GA IKIA P EG ++
Sbjct: 372 FGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSE 430
Query: 330 RQVTITGSAASISLAQYLINVRLSSE 355
R V ITG + AQ I +L E
Sbjct: 431 RMVIITGPPEAQFKAQGRIFGKLKEE 456
Score = 55.5 bits (132), Expect = 7e-08
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 73.9 bits (180), Expect = 2e-13
Identities = 86/355 (24%), Positives = 151/355 (42%), Gaps = 58/355 (16%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
++ ++ D+ + ER IT+ G ++ +I + E+ + + + + P
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVNQQANLIP 364
Query: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPDLTKL 242
+ +STG S P P PP Y T G ++ P
Sbjct: 365 GLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH---- 412
Query: 243 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGR 302
HQ FP H S PE + L IP +G IIG+
Sbjct: 413 HQF----GPFPHHH----------SYPEQE-------------IVNLFIPTQAVGAIIGK 445
Query: 303 QGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 355
+GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 446 KGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 545 VPRDQTPDENEEVI 558
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 3e-13
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 22/183 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
Query: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Query: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLESP--PKGVTIPYRPKPS 183
GA++++ + PN+ + TI G PQ I+ +Q+ + P P G +P+ P
Sbjct: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPHGPHGV 465
Query: 184 SSP 186
P
Sbjct: 466 PGP 468
Score = 71.6 bits (174), Expect = 1e-12
Identities = 84/362 (23%), Positives = 146/362 (40%), Gaps = 44/362 (12%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
Query: 142 TERAITIAGIPQSIIECVKQICVVMLE---------------SPPKGVTIPYRPKPSSSP 186
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
Query: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIP-QPDLTK 241
VI G+ +D+ P P+ + GPP Q+A DL +
Sbjct: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHAAEIITDLLR 344
Query: 242 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIG 301
Q P G G + P GL +P G IIG
Sbjct: 345 SVQAGNPGGPGPGGRGRGRGQGNWNMGPP-----GGLQ------EFNFIVPTGKTGLIIG 393
Query: 302 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGG 358
+ G I I Q SGA+I++ + D + TI G+ I A+ LI ++
Sbjct: 394 KGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNP 453
Query: 359 MG 360
+G
Sbjct: 454 LG 455
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 281 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 340
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
Query: 341 ISLAQYLIN 349
+ A+ L++
Sbjct: 157 VQSAKRLLD 165
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/277 (22%), Positives = 105/277 (37%), Gaps = 36/277 (12%)
Query: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
Query: 152 PQSIIECVKQICVVMLES--PPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTT 209
P+S ++ K++ ++E P G P + ++ + G +
Sbjct: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
Query: 210 PSMCL-------NPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS 262
+ P G Y + Q ++ + GF
Sbjct: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQ----------AKEMVLELIRDQGGFR 262
Query: 263 GIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 322
+ + G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 263 EVRNEYGSRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-K 312
Query: 323 PVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 358
P +G+T +R ITG A +I L S G
Sbjct: 313 PDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/141 (22%), Positives = 68/141 (48%), Gaps = 7/141 (4%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
Query: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
Query: 132 QVAGDMLPNSTERAITIAGIP 152
Q D + ER I G P
Sbjct: 310 QFKPDD-GTTPERIAQITGPP 329
Score = 35.8 bits (81), Expect = 0.061
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
Query: 79 L 79
+
Sbjct: 447 I 447
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
Query: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
A I+ K+ E + + +S+A PP +
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
Query: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
Query: 151 IPQS 154
P++
Sbjct: 320 PPEA 323
Score = 38.5 bits (88), Expect = 0.009
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 346
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
Query: 347 LINVRLSSE 355
I +L E
Sbjct: 330 RIYGKLKEE 338
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
Query: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
Query: 130 QVQVAGDMLPNSTERAI 146
+V V D P+ ++ +
Sbjct: 520 EVVVPRDQTPDENDQVV 536
Score = 63.5 bits (153), Expect = 3e-10
Identities = 49/186 (26%), Positives = 82/186 (44%), Gaps = 45/186 (24%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAI 68
+ +++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G
Sbjct: 277 IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETC 336
Query: 69 FKAFAMIIDKL----EEDISS----------------SMTNSTAASRPPV---------- 98
KA I+ K+ E DI+S + T+ PP
Sbjct: 337 AKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPP 396
Query: 99 ----------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITI 148
T+ L +PA G++IGK G IK++ GA +++A P++ R + I
Sbjct: 397 YPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVII 456
Query: 149 AGIPQS 154
G P++
Sbjct: 457 TGPPEA 462
Score = 56.2 bits (134), Expect = 4e-08
Identities = 84/350 (24%), Positives = 147/350 (42%), Gaps = 76/350 (21%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
Query: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 128 GAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPV 187
+ ITI+ + + + L +P + +T+ + +
Sbjct: 307 DTK---------------ITISPLQE-----------LTLYNPERTITVKGNVETCAKAE 340
Query: 188 IFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAM 247
+ R S +D AS L+A+ I G L+ L +
Sbjct: 341 EEIMKKIRESYENDIASMN----------------LQAHLIPG---------LNLNALGL 375
Query: 248 QQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKI 307
FP T +G S P ++T + L IP +G IIG+QG I
Sbjct: 376 ----FPPT---SGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHI 428
Query: 308 NEIRQMSGAQIKIANPVEG--STDRQVTITGSAASISLAQYLINVRLSSE 355
++ + +GA IKIA P E + R V ITG + AQ I ++ E
Sbjct: 429 KQLSRFAGASIKIA-PAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEE 477
Score = 35.8 bits (81), Expect = 0.061
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)
Query: 218 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAG 277
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPG---- 186
Query: 278 LDASAQTTSH---ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVT 333
S Q L +P +G IIG++GA I I + + ++I + G+ ++ +T
Sbjct: 187 -SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT 245
Query: 334 ITGSAASISLA 344
I + S A
Sbjct: 246 ILSTPEGTSAA 256
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 523 VPRDQTPDENDQVI 536
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338
Query: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
A I+ K+ E + + +S+A PP +
Sbjct: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398
Query: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458
Query: 151 IPQS 154
P++
Sbjct: 459 PPEA 462
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/156 (22%), Positives = 80/156 (51%), Gaps = 11/156 (7%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQI 162
++ ++ D+ + ER IT+ G ++ ++I
Sbjct: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEI 343
Score = 42.7 bits (99), Expect = 5e-04
Identities = 21/69 (30%), Positives = 36/69 (52%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSS 255
Query: 158 CVKQICVVM 166
K I +M
Sbjct: 256 ACKMILEIM 264
Score = 38.5 bits (88), Expect = 0.009
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 346
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 409 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 468
Query: 347 LINVRLSSE 355
I +L E
Sbjct: 469 RIYGKLKEE 477
Score = 30.4 bits (67), Expect = 2.6
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 10/130 (7%)
Query: 229 QGQYAIPQPDLTKLHQLAMQQSHFP-------MTHGNTGFSGIESSSPEVKGYWAGLDAS 281
Q + AI + + +L A++ S+ P +G G G + AG A
Sbjct: 131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAK 190
Query: 282 AQTTSH--ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGSA 338
Q L +P +G IIG++GA I I + + ++I + G+ ++ +++ +
Sbjct: 191 QQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTP 250
Query: 339 ASISLAQYLI 348
S A +I
Sbjct: 251 EGCSSACKMI 260
>gi|122937472 bicaudal C homolog 1 [Homo sapiens]
Length = 974
Score = 57.0 bits (136), Expect = 3e-08
Identities = 82/334 (24%), Positives = 134/334 (40%), Gaps = 69/334 (20%)
Query: 30 GKKGESV-KKMREESGARI------NISEGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
G+ GE +K+ EE+ +I I + + I ++G + +A MI+ L+
Sbjct: 70 GRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLD-- 127
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST 142
T ++R VTL++ V ++ +IGKGG IK++ E TG + N
Sbjct: 128 --------TKSNR--VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQA 177
Query: 143 ERA--ITIAGIPQSIIECVKQI-----CVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDR 195
E++ ++IAG P + +I V+M E P G+ P P P+S + Q
Sbjct: 178 EKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPV-PDPNSPSI-----QHI 231
Query: 196 YSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMT 255
T + S SF + + G +
Sbjct: 232 SQTYNISVSFKQRSRMYGATVIVRG----------------------------------S 257
Query: 256 HGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSG 315
NT S ++ + + + AG ASA S +L I ++GR G+ I I Q +G
Sbjct: 258 QNNT--SAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTG 315
Query: 316 AQIKIANPVEGSTDRQVTITGSAASISLA-QYLI 348
AQI +P V + G+ S+ LA QYL+
Sbjct: 316 AQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLM 349
Score = 32.0 bits (71), Expect = 0.89
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN 53
+T+++ + E +IGK G ++KK+ EE+G I+ + N
Sbjct: 133 VTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSN 172
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 5e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 343
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 344 AQYLINVRLSSE 355
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 347
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 348 INVRLSSET 356
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 42.7 bits (99), Expect = 5e-04
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQ 193
P + + I ++ E+ P + P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-PQRSVGRIIGRGGE 145
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 286 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 343
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 344 AQYLINVRLSSE 355
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 347
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 348 INVRLSSET 356
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,464,984
Number of Sequences: 37866
Number of extensions: 693319
Number of successful extensions: 1696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 1305
Number of HSP's gapped (non-prelim): 285
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.