Guide to the Human Genome
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Search of human proteins with 7657496

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo
sapiens]
         (491 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo ...   996   0.0  
gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo s...    86   1e-16
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]     67   4e-11
gi|40353729 Ras and Rab interactor 3 [Homo sapiens]                    59   8e-09
gi|18466802 Ras and Rab interactor 2 [Homo sapiens]                    58   2e-08
gi|68989256 ras inhibitor RIN1 [Homo sapiens]                          53   6e-07
gi|156231049 zinc finger, AN1-type domain 5 [Homo sapiens]             45   1e-04
gi|156231047 zinc finger, AN1-type domain 5 [Homo sapiens]             45   1e-04
gi|5174755 zinc finger, AN1-type domain 5 [Homo sapiens]               45   1e-04
gi|21359918 zinc finger, AN1-type domain 6 [Homo sapiens]              43   6e-04
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]         42   0.001
gi|224458301 family with sequence similarity 186, member A [Homo...    40   0.004
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    39   0.008
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              39   0.011
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    39   0.011
gi|40316935 alsin isoform 1 [Homo sapiens]                             39   0.014
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.053
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.053
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             37   0.053
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    37   0.053
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    36   0.070
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    36   0.091
gi|118026942 zinc finger protein Cezanne [Homo sapiens]                36   0.091
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    36   0.091
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    36   0.091
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            35   0.12 
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    35   0.16 
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    35   0.16 
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]      35   0.16 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.16 

>gi|7657496 RAB guanine nucleotide exchange factor (GEF) 1 [Homo
           sapiens]
          Length = 491

 Score =  996 bits (2575), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 1   MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAER 60
           MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAER
Sbjct: 1   MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAER 60

Query: 61  LQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEA 120
           LQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEA
Sbjct: 61  LQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEA 120

Query: 121 KAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSE 180
           KAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSE
Sbjct: 121 KAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSE 180

Query: 181 CAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQK 240
           CAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQK
Sbjct: 181 CAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQK 240

Query: 241 RIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFN 300
           RIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFN
Sbjct: 241 RIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFN 300

Query: 301 AIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLC 360
           AIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLC
Sbjct: 301 AIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLC 360

Query: 361 CAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQL 420
           CAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQL
Sbjct: 361 CAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQL 420

Query: 421 NERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKL 480
           NERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKL
Sbjct: 421 NERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKL 480

Query: 481 PPPLQPQVYAG 491
           PPPLQPQVYAG
Sbjct: 481 PPPLQPQVYAG 491


>gi|51093832 GTPase activating protein and VPS9 domains 1 [Homo
            sapiens]
          Length = 1487

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 49/176 (27%), Positives = 92/176 (52%), Gaps = 15/176 (8%)

Query: 202  ERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDI 261
            E+++     IE+ +M R++K  F P    D  +D  + + I+ L  V      V  N   
Sbjct: 1317 EQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKV------VTANHRA 1370

Query: 262  PEVSDMVVK------AITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPA-SADD 314
             ++ ++ ++      A ++I  + + + PRDK+ CI +    I N + +   +    ADD
Sbjct: 1371 LQIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADD 1430

Query: 315  FLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLD 370
            F+P L+++++K NPP L S +QYI+ F   +  ++GE+ Y++     AV FI+ +D
Sbjct: 1431 FVPVLVFVLIKANPPCLLSTVQYISSFY--ASCLSGEESYWWMQFTAAVEFIKTID 1484


>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
          Length = 1050

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 77/326 (23%), Positives = 137/326 (42%), Gaps = 26/326 (7%)

Query: 86  FEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIET----DRVSKE 141
           FEE   NEK    + +        R  S    +E  APS   + +T  +      R S+ 
Sbjct: 96  FEETFYNEKEESFSILCIAHPLEKRESS----EEPLAPSDPFSLKTIEDVREFLGRHSER 151

Query: 142 FIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPP 201
           F   + +FH+T +E  +++      + +  D +    ++C Q    +   +M  + +   
Sbjct: 152 FDRNIASFHRTFRECERKS------LRHHIDSANALYTKCLQQLLRDSHLKMLAKQEA-- 203

Query: 202 ERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDI 261
            ++  +   +E Y+   +Y  +F    T +  +D A  K  R+L+ +  + + V      
Sbjct: 204 -QMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVK----- 257

Query: 262 PEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKN-EPASADDFLPTLI 320
           PE S  + +A  ++ +++    P+ KL C+ K  + I  +     N E   ADD L  L+
Sbjct: 258 PEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLL 317

Query: 321 YIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQED 380
           Y+++K   P   +N+ YI  F   S L   E GY  T+   A+ +I +    +     E 
Sbjct: 318 YLLVKTEIPNWMANLSYIKNF-RFSSLAKDELGYCLTSFEAAIEYIRQGSLSAKPPESEG 376

Query: 381 F-DRYMSGQTSPRKQEAESWSPDACL 405
           F DR    Q      +  S SP  CL
Sbjct: 377 FGDRLFLKQRMSLLSQMTS-SPTDCL 401


>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
          Length = 985

 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 45/171 (26%), Positives = 81/171 (47%), Gaps = 11/171 (6%)

Query: 209 DQIEKYIMTRLYKYVFCP--ETTDD-----EKKDLAIQK-RIRALRWVTPQMLCVPVNED 260
           +++E  + + LYK V  P  E  +        KD ++Q+ +   L  +      + V   
Sbjct: 673 EELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVILATTTTDLGVTTS 732

Query: 261 IPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKI-TKNEPASADDFLPTL 319
           +PEV  M+ K +     M     P  K++ + K  K I++++ +    +P  ADDFLP L
Sbjct: 733 VPEVP-MMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVL 791

Query: 320 IYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLD 370
           +Y++ + N   +  N++Y+    +P+ L  GE  YY T    A+  I+  D
Sbjct: 792 MYVLARSNLTEMLLNVEYMMELMDPA-LQLGEGSYYLTTTYGALEHIKSYD 841


>gi|18466802 Ras and Rab interactor 2 [Homo sapiens]
          Length = 895

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 13/153 (8%)

Query: 238 IQKRIRALRWVTPQMLCV-PVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSK 296
           +++ ++ +R   PQ L V     D  +V  + VK +T    M     P  K+  + +  K
Sbjct: 624 LKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMT----MQKMYSPEKKVMLLLRVCK 679

Query: 297 HIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYF 356
            I+  ++        ADDFLP L Y++ + +   L + I+Y+    +PS L+ GE GYY 
Sbjct: 680 LIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPS-LLHGEGGYYL 738

Query: 357 TNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQT 389
           T+   A++ I+       N  +E   R +S +T
Sbjct: 739 TSAYGALSLIK-------NFQEEQAARLLSSET 764


>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
          Length = 783

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 284 PRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCN 343
           P  ++  + +  K ++ A++  + E A AD+FLP L  ++   + P L    +Y++    
Sbjct: 508 PSAQVKRLLQACKLLYMALRTQEGEGAGADEFLPLLSLVLAHCDLPELLLEAEYMSELLE 567

Query: 344 PSRLMTGEDGYYFTNLCCAVAFIEKL-DAQSLNLS 377
           PS L+TGE GYY T+L  ++A +  L  A +L LS
Sbjct: 568 PS-LLTGEGGYYLTSLSASLALLSGLGQAHTLPLS 601


>gi|156231049 zinc finger, AN1-type domain 5 [Homo sapiens]
          Length = 213

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 27/143 (18%)

Query: 17  LLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQ 76
           +LC  GCG+YGNP   G CS C++E  H  RQ+        + R+      + ++S +S 
Sbjct: 12  MLCSTGCGFYGNPRTNGMCSVCYKE--HLQRQQN-------SGRMSPMGTASGSNSPTSD 62

Query: 77  GAQ------SLTFSKFEEKKTNEKTRKVTT---------VKKFFSASSRVGS-KKEIQE- 119
            A       SL   +     T+EK+R V            +   S   ++ + K E+ E 
Sbjct: 63  SASVQRADTSLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEP 122

Query: 120 -AKAPSPSINRQTSIETDRVSKE 141
               PSPS+++ ++ +++  + E
Sbjct: 123 VVTQPSPSVSQPSTSQSEEKAPE 145


>gi|156231047 zinc finger, AN1-type domain 5 [Homo sapiens]
          Length = 213

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 27/143 (18%)

Query: 17  LLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQ 76
           +LC  GCG+YGNP   G CS C++E  H  RQ+        + R+      + ++S +S 
Sbjct: 12  MLCSTGCGFYGNPRTNGMCSVCYKE--HLQRQQN-------SGRMSPMGTASGSNSPTSD 62

Query: 77  GAQ------SLTFSKFEEKKTNEKTRKVTT---------VKKFFSASSRVGS-KKEIQE- 119
            A       SL   +     T+EK+R V            +   S   ++ + K E+ E 
Sbjct: 63  SASVQRADTSLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEP 122

Query: 120 -AKAPSPSINRQTSIETDRVSKE 141
               PSPS+++ ++ +++  + E
Sbjct: 123 VVTQPSPSVSQPSTSQSEEKAPE 145


>gi|5174755 zinc finger, AN1-type domain 5 [Homo sapiens]
          Length = 213

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 27/143 (18%)

Query: 17  LLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQ 76
           +LC  GCG+YGNP   G CS C++E  H  RQ+        + R+      + ++S +S 
Sbjct: 12  MLCSTGCGFYGNPRTNGMCSVCYKE--HLQRQQN-------SGRMSPMGTASGSNSPTSD 62

Query: 77  GAQ------SLTFSKFEEKKTNEKTRKVTT---------VKKFFSASSRVGS-KKEIQE- 119
            A       SL   +     T+EK+R V            +   S   ++ + K E+ E 
Sbjct: 63  SASVQRADTSLNNCEGAAGSTSEKSRNVPVAALPVTQQMTEMSISREDKITTPKTEVSEP 122

Query: 120 -AKAPSPSINRQTSIETDRVSKE 141
               PSPS+++ ++ +++  + E
Sbjct: 123 VVTQPSPSVSQPSTSQSEEKAPE 145


>gi|21359918 zinc finger, AN1-type domain 6 [Homo sapiens]
          Length = 208

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 2/35 (5%)

Query: 14 QSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQ 48
          Q  +LC  GCG+YGNP   G CS C++E  H  RQ
Sbjct: 9  QVPMLCSTGCGFYGNPRTNGMCSVCYKE--HLQRQ 41


>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
          Length = 631

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 312 ADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKL 369
           ADD LP L ++VL+   P+L S    +  F +   L+ GE+GY  T+L  A++++E L
Sbjct: 568 ADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLI-GEEGYCLTSLQSALSYVELL 624


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 31   WQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQS-SQGAQSLTFSKFEEK 89
            WQ    + W+EE  +A  KQ +++ +  +R Q EEE   +S Q   +G Q +       +
Sbjct: 883  WQE--EEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMKTQGLLLE 940

Query: 90   KTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKE-------- 141
            K N + R++    K      R    KE Q+ +     + RQ   +     KE        
Sbjct: 941  KENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKELEK 1000

Query: 142  -FIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEE 177
              I+   T     + + K  +   EG  ++R+L   E
Sbjct: 1001 MVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLE 1037



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/132 (20%), Positives = 53/132 (40%), Gaps = 9/132 (6%)

Query: 37  KCWREEYHKARQKQIQEDWELAERLQREEEEAF------ASSQSSQGAQSLTFSKFEEKK 90
           K W +     +++Q Q+ W+  E  + E+++A          Q  +G +     K   ++
Sbjct: 865 KAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQR 924

Query: 91  TNEKTRKVTTVKKFFSASSRVGSKKEIQ-EAKAPSPSINRQTSIETDRVSKEFIEFLKTF 149
             E T+K+ T        +  G  ++IQ EAK   P   R+   E  +  +   +  +  
Sbjct: 925 LEEGTQKMKTQGLLLEKEN--GQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQI 982

Query: 150 HKTGQEIYKQTK 161
               Q   K+T+
Sbjct: 983 KTKDQMQMKETQ 994


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 12/181 (6%)

Query: 37  KCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTR 96
           K   EE  + R+K+++E+    E + RE+EE     +     Q     + EEK   ++ +
Sbjct: 584 KMREEERMREREKKMREE----EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639

Query: 97  KVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEI 156
                +K +    ++  ++ + E K       +    E  +  +E I   +   K  QE 
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699

Query: 157 YKQT----KLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIE 212
            K+T    K+  E    +R+  + E+ E  ++      E+MQ + +   E+ E++ +Q E
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMRE----QEEKMQEQEEKMQEQEEEMWEQEE 755

Query: 213 K 213
           K
Sbjct: 756 K 756



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 40/189 (21%), Positives = 80/189 (42%), Gaps = 22/189 (11%)

Query: 42  EYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEK------------ 89
           E  +  Q+Q ++ WE  E++ RE+EE     +     Q     + E+K            
Sbjct: 345 EQEEQMQEQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 403

Query: 90  -KTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRV---SKEFIEF 145
            +  EK  ++   +K +    ++  +K++QE +  +     +   E +R+    K+  E 
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD-QEEKMQEEERIREREKKMREE 462

Query: 146 LKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVE 205
            +T  +  +++ KQ     E M  + +   ++Q    Q       E+MQ + +   E+ E
Sbjct: 463 EETMREQEEKMQKQE----ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518

Query: 206 KIMDQIEKY 214
           KI DQ E +
Sbjct: 519 KIRDQEEMW 527


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 27/181 (14%)

Query: 39  WREEYHKARQKQIQEDWELAERLQREEE------EAFASSQSSQGAQSLTFSKFEEKKTN 92
           W++E  K+R+K +  +   +++ +R+++       + +SS SS  + S + S+ EEKK  
Sbjct: 69  WKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQG 128

Query: 93  EKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKT 152
           ++ +K    KK  S  S   S  E +     S    +++  ET++             K 
Sbjct: 129 KRRKK----KKNRSYKSSQSSTHESESESKESVKKKKKSKDETEK------------EKD 172

Query: 153 GQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIE 212
            + + K+ K       Y  D  +  +S    D+  +V  + + R +   +  EK+  + +
Sbjct: 173 VRSLSKKRK-----KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKK 227

Query: 213 K 213
           K
Sbjct: 228 K 228


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 40/174 (22%)

Query: 45  KARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKF 104
           K RQ ++Q++ E  ER+++EE++     +  + A+       EE +  E+ R        
Sbjct: 407 KRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER-------- 458

Query: 105 FSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFL 164
                    K++ +E K       R+   E  R ++E     +   K  QE  KQ K   
Sbjct: 459 ---------KRQEEEKKKQEGEEKRKAGEEAKRKAEE-----ELLLKEKQEQEKQEKAM- 503

Query: 165 EGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTR 218
                     IE+Q E A+     VAE+M+       ER E+IM QIE+  + R
Sbjct: 504 ----------IEKQKEAAETKAREVAEQMRL------ER-EQIMLQIEQERLER 540


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 271  AITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPA--SADDFLPTLIYIVLKGNP 328
            A+  + ++ +   P DKL  I +  + I  ++  + +E    S DD  P  +Y+VL+   
Sbjct: 1555 AVECLQQISTTFTPSDKLKVIQQTFEEISQSVLASLHEDFLWSMDDLFPVFLYVVLRARI 1614

Query: 329  PRLQSNIQYITRFCNPSRLMTGEDGYYFTNL 359
              L S +  I    +P  L  GE G  FT L
Sbjct: 1615 RNLGSEVHLIEDLMDP-YLQHGEQGIMFTTL 1644


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 12/103 (11%)

Query: 41  EEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTT 100
           E+  KA++KQ  E+ E+ E+ Q+ +EE     +S Q       +K E+K+T+ K  K  T
Sbjct: 498 EQEQKAKKKQEAEENEITEKQQKAKEE-MEKKESEQ-------AKKEDKETSAKRGKEIT 549

Query: 101 VKKFFSASSRVGS--KKEIQE--AKAPSPSINRQTSIETDRVS 139
             K  S S    S  KK +++   + P+P I ++++ +    S
Sbjct: 550 GVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTS 592


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 12/103 (11%)

Query: 41  EEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTT 100
           E+  KA++KQ  E+ E+ E+ Q+ +EE     +S Q       +K E+K+T+ K  K  T
Sbjct: 498 EQEQKAKKKQEAEENEITEKQQKAKEE-MEKKESEQ-------AKKEDKETSAKRGKEIT 549

Query: 101 VKKFFSASSRVGS--KKEIQE--AKAPSPSINRQTSIETDRVS 139
             K  S S    S  KK +++   + P+P I ++++ +    S
Sbjct: 550 GVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTS 592


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 12/103 (11%)

Query: 41  EEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTT 100
           E+  KA++KQ  E+ E+ E+ Q+ +EE     +S Q       +K E+K+T+ K  K  T
Sbjct: 498 EQEQKAKKKQEAEENEITEKQQKAKEE-MEKKESEQ-------AKKEDKETSAKRGKEIT 549

Query: 101 VKKFFSASSRVGS--KKEIQE--AKAPSPSINRQTSIETDRVS 139
             K  S S    S  KK +++   + P+P I ++++ +    S
Sbjct: 550 GVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTS 592


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKF---EEKKTNEKTR 96
           R E  +AR+K  Q + E  ERLQ+++EEA A S+     Q L   K    +E++  E+ +
Sbjct: 652 RREEQEAREKA-QAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRK 710

Query: 97  KVTTVKKFFSASSRVGSKKEIQEAK 121
           ++  + K  +  S V   K+ Q++K
Sbjct: 711 RLEEIMK-RTRKSEVSETKQKQDSK 734



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVT 99
           R +  + R+++ QE    AER +R  EE  A    ++  +     + EE++  EK     
Sbjct: 607 RRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREK----- 661

Query: 100 TVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQ 159
                  A +    ++ +Q+ K  + + +R+ + E  R+ +E     K F +  QE  ++
Sbjct: 662 -------AQAEQEEQERLQKQKEEAEARSREEA-ERQRLERE-----KHFQQQEQERQER 708

Query: 160 TKLFLEGMHYKRDLSIEEQSE 180
            K   E M   R   + E  +
Sbjct: 709 RKRLEEIMKRTRKSEVSETKQ 729


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 40/183 (21%), Positives = 75/183 (40%), Gaps = 21/183 (11%)

Query: 37  KCWREEYHKARQKQIQEDWELAERLQREE------EEAFASSQSSQGAQSLTFSKFEEKK 90
           K W EE    RQ+Q  + W   E+++ +E      EE     +  +  Q     K EEK 
Sbjct: 558 KIWEEE---KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614

Query: 91  TNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFH 150
             ++ +     +K      ++  ++E+ + +        +   E +   +E  E   T  
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE---TMW 671

Query: 151 KTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQ 210
           +  ++I +Q K   E     ++  I EQ E  Q+      E+M  + +   E+ EK+ +Q
Sbjct: 672 RQEEKIREQEKKIRE-----QEEKIREQEEMMQE----QEEKMWEQEEKMCEQEEKMQEQ 722

Query: 211 IEK 213
            EK
Sbjct: 723 EEK 725



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 35/183 (19%), Positives = 83/183 (45%), Gaps = 11/183 (6%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTN-----EK 94
           RE+  K R+++ +  WE  E+++R+EE  +   +  +  + + + K E+ +       EK
Sbjct: 331 REQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 389

Query: 95  TRKVTTVKKFFSASSRVGSKKE--IQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKT 152
             K+  +++      ++  ++E   +E K       ++   +  R  ++  E  +   + 
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449

Query: 153 GQEIYKQTKLFLEGMHYKRDLSIEEQSEC--AQDFYHNVAERMQTRGKVPPERVEKIMDQ 210
            +++++Q +   E    + +   +EQ E    ++  H   E  + + K+  E+ EKI  Q
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM-HEQEEKIRKQ 508

Query: 211 IEK 213
            EK
Sbjct: 509 EEK 511



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 26/141 (18%), Positives = 60/141 (42%), Gaps = 5/141 (3%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVT 99
           +EE  +  ++++ E  ++ E+ ++ +EE     Q  +  Q     + EEK   ++ +   
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448

Query: 100 TVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQ 159
             KK +    ++  +++I+E +            E     +E     +  H+  ++I KQ
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508

Query: 160 TKLFLEGMHYKRDLSIEEQSE 180
                E   ++++  I EQ E
Sbjct: 509 -----EEKVWRQEEKIREQEE 524


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 17/179 (9%)

Query: 36  SKCWR-EEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEK 94
           +K WR EE  + ++++I+E     E + +E+EE     +     Q     + EEK   ++
Sbjct: 383 AKMWRQEEKIREQEEKIREQ----EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438

Query: 95  TRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQ 154
            +     KK      ++  ++E+ + +            E +   +E  E ++   +  +
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR---RQEE 495

Query: 155 EIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEK 213
           +I +Q K   E     ++  I EQ E  Q+      E+M  + +   E+ EK+ +Q EK
Sbjct: 496 KIREQEKKIRE-----QEEKIREQEEMMQE----QEEKMWEQEEKMCEQEEKMQEQEEK 545



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 26/187 (13%)

Query: 37  KCWR-EEYHKARQKQIQEDWELA----ERLQREEEEAFASSQSSQGAQSLTFSK------ 85
           K WR EE  + R+++IQE  E      E+++R+EE  +   +  +  + + + K      
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348

Query: 86  FEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEF 145
            EEK   ++  +    K+      R   K++ QEAK        +   E  R  +E ++ 
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ- 407

Query: 146 LKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVE 205
            +   K G++         E   ++++  ++EQ E  +       E+++ + K   E+ E
Sbjct: 408 -EQEEKMGEQ---------EEKMWEQEEEMQEQEEKMR----RQEEKIREQEKKIREQEE 453

Query: 206 KIMDQIE 212
           KI +Q E
Sbjct: 454 KIREQEE 460


>gi|118026942 zinc finger protein Cezanne [Homo sapiens]
          Length = 843

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 4/40 (10%)

Query: 19  CKK-GCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWEL 57
           CK+  C +YG+P    FCS C+REE    R+++ + D EL
Sbjct: 802 CKQPNCSFYGHPETNNFCSCCYREE---LRRREREPDGEL 838


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 33/182 (18%)

Query: 39  WREEYHKARQKQIQEDWELAERLQREEEE-------AFASSQSSQGAQSLTFSKFEEKKT 91
           W++E  K R+K +      +++ QR+++E       + +SS SS  + S + S+ E+KK 
Sbjct: 59  WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 118

Query: 92  NEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHK 151
            ++ +K    KK  S  S   S+  + E ++ S    ++     D   KE         K
Sbjct: 119 GKRRKK----KKNRSHKS---SESSMSETESDSKDSLKKKKKSKDGTEKE---------K 162

Query: 152 TGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQI 211
             + + K+ K++ E     + LS E  SE          E ++ + K   E  EK  ++ 
Sbjct: 163 DIKGLSKKRKMYSE----DKPLSSESLSE------SEYIEEVRAKKKKSSEEREKATEKT 212

Query: 212 EK 213
           +K
Sbjct: 213 KK 214


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 33/182 (18%)

Query: 39  WREEYHKARQKQIQEDWELAERLQREEEE-------AFASSQSSQGAQSLTFSKFEEKKT 91
           W++E  K R+K +      +++ QR+++E       + +SS SS  + S + S+ E+KK 
Sbjct: 69  WKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQ 128

Query: 92  NEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHK 151
            ++ +K    KK  S  S   S+  + E ++ S    ++     D   KE         K
Sbjct: 129 GKRRKK----KKNRSHKS---SESSMSETESDSKDSLKKKKKSKDGTEKE---------K 172

Query: 152 TGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQI 211
             + + K+ K++ E     + LS E  SE          E ++ + K   E  EK  ++ 
Sbjct: 173 DIKGLSKKRKMYSE----DKPLSSESLSE------SEYIEEVRAKKKKSSEEREKATEKT 222

Query: 212 EK 213
           +K
Sbjct: 223 KK 224


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 35/180 (19%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 41  EEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTT 100
           EE  + R+K+++E+    E + RE+EE     +     Q     + EEK   ++ +    
Sbjct: 4   EERMREREKKMREE----EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59

Query: 101 VKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSK----EFIEFLKTFHKTGQEI 156
            +K +    ++  ++ + E K      + +   + +R+ +    + +E ++   KT +E 
Sbjct: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119

Query: 157 YKQTKLFL---EGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEK 213
            ++ +  +   E M ++++  ++EQ E   +      E+M+ + +   E+ EK+  Q EK
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----QEEKMREQEEKMREQEEKMQGQEEK 175



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 4/66 (6%)

Query: 37  KCWREEYHKARQKQIQED----WELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTN 92
           K W +E     Q+++ E     WE  ERL+ +EE         Q  +     K +E+K  
Sbjct: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121

Query: 93  EKTRKV 98
           E+  K+
Sbjct: 122 EQEEKM 127


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 38/182 (20%), Positives = 81/182 (44%), Gaps = 9/182 (4%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSK------FEEKKTNE 93
           RE+  K R+++ +  WE  E+++R+EE  +   +  +  + + + K       EEK   +
Sbjct: 392 REQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450

Query: 94  KTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTG 153
           +  +    K+      R   K++ QEAK        +   E  R  +E +   +      
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510

Query: 154 QEIYKQTKLFLEGMHYKRDLSIEEQSEC--AQDFYHNVAERMQTRGKVPPERVEKIMDQI 211
           ++I ++ K   +   ++++  I EQ E    ++  H   E+++ + +    + EK+ DQ 
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570

Query: 212 EK 213
           EK
Sbjct: 571 EK 572



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 32/176 (18%), Positives = 78/176 (44%), Gaps = 8/176 (4%)

Query: 40  REEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVT 99
           +EE  +  ++++ E  ++ E+ ++ +EE     Q  +  Q     + EEK   ++ +   
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495

Query: 100 TVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQ 159
             +K +    ++  +++I+E +            E  R  +E     +  H+  ++I KQ
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555

Query: 160 TKLFLEGMHYKRDLSIEEQSECAQDFYHNV---AERMQTRGKVPPERVEKIMDQIE 212
                E   ++++  + +Q E  ++    V    E+++ + +   E+ EKI +Q E
Sbjct: 556 -----EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 26/177 (14%)

Query: 37  KCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTR 96
           K WR+E     Q++I+E     E  ++E+EE +   +  +  + +   K +  +  EK R
Sbjct: 499 KMWRQEEKIHEQEKIRE-----EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553

Query: 97  KVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEI 156
           K    +K +    R   K   QE K       R+   +  R  ++  E  +   +  ++I
Sbjct: 554 K--QEEKMW----RQEEKMHDQEEKI------REQEEKVWRQEEKIREQEEKIREQEEKI 601

Query: 157 YKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEK 213
            +Q ++  E    +  +  +E+  C Q+      E+MQ + +    + EKI +Q +K
Sbjct: 602 REQEEMTQE---QEEKMGEQEEKMCEQE------EKMQEQEEKMRRQEEKIREQEKK 649


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 4/106 (3%)

Query: 36  SKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKT 95
           SK   E   +   ++ +E+ E  E  + EEEE         G QS        +K  +K 
Sbjct: 287 SKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKW 346

Query: 96  RKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKE 141
           RK +   K     SR   K+E   AK P    N  +S+ET+R  +E
Sbjct: 347 RKDSPWVK----PSRKRRKREPPRAKEPRGVSNDTSSLETERGFEE 388


>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
          Length = 822

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 33/162 (20%), Positives = 63/162 (38%), Gaps = 2/162 (1%)

Query: 37  KCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTR 96
           K   EE  + +Q  + ++  + E  +R EE +    + S     L+  +  E+      +
Sbjct: 310 KTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQ 369

Query: 97  KVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIE--TDRVSKEFIEFLKTFHKTGQ 154
              T  KF +    +  K +  + K P P +N +      T    KE +   ++   +  
Sbjct: 370 LRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIA 429

Query: 155 EIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTR 196
            I +  K  L        +SI E+    QD+YH    R++ +
Sbjct: 430 GIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQ 471


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 389  TSPRKQEAESWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIARE 448
            +S  KQ  +  SP   +  +++    DLL + NE+++R +  A    K+L+     +  E
Sbjct: 956  SSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1015

Query: 449  VQDIVEKYPLEIKPPNQPLAAIDSENVENDK 479
            + ++ ++   EI     PL+  +   VE DK
Sbjct: 1016 LANLKDESKKEI-----PLSETERGEVEEDK 1041



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 29/138 (21%), Positives = 59/138 (42%), Gaps = 14/138 (10%)

Query: 39   WREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKV 98
            W+ E H+ R ++    WE+ ER + +E+   A S   Q    L     E + ++ +T+ +
Sbjct: 2945 WQHELHQLRMEK--SSWEIHER-RMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPL 3001

Query: 99   TTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYK 158
                       +V  +++     + SP  ++    ET+ +  +  + LK  H+    I +
Sbjct: 3002 -----------KVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQ 3050

Query: 159  QTKLFLEGMHYKRDLSIE 176
                F + +  K  LSI+
Sbjct: 3051 LNSNFSQLLEEKNTLSIQ 3068


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,132,655
Number of Sequences: 37866
Number of extensions: 848983
Number of successful extensions: 4206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 3908
Number of HSP's gapped (non-prelim): 340
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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