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Search of human proteins with 7657465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657465 podocalyxin-like 2 [Homo sapiens]
(605 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657465 podocalyxin-like 2 [Homo sapiens] 1214 0.0
gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens] 70 4e-12
gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens] 69 1e-11
gi|17975763 myelin transcription factor 1 [Homo sapiens] 65 2e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 63 9e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 57 4e-08
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 57 6e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 55 1e-07
gi|38373682 pleckstrin homology domain containing family G membe... 55 1e-07
gi|111154084 pleckstrin homology domain containing family G memb... 55 1e-07
gi|111154088 pleckstrin homology domain containing family G memb... 55 1e-07
gi|111154080 pleckstrin homology domain containing family G memb... 55 1e-07
gi|111154078 pleckstrin homology domain containing family G memb... 55 1e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 2e-07
gi|118600967 shroom family member 4 [Homo sapiens] 55 2e-07
gi|38372931 brevican isoform 2 [Homo sapiens] 53 9e-07
gi|38372935 brevican isoform 1 [Homo sapiens] 53 9e-07
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 52 1e-06
gi|38176300 nestin [Homo sapiens] 52 2e-06
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 52 2e-06
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 49 1e-05
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 49 1e-05
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 49 1e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 49 1e-05
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 49 2e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 49 2e-05
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 49 2e-05
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 49 2e-05
gi|7661690 coiled-coil domain containing 9 [Homo sapiens] 49 2e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 48 2e-05
>gi|7657465 podocalyxin-like 2 [Homo sapiens]
Length = 605
Score = 1214 bits (3140), Expect = 0.0
Identities = 605/605 (100%), Positives = 605/605 (100%)
Query: 1 MGRLLRAARLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLPTGLEPLD 60
MGRLLRAARLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLPTGLEPLD
Sbjct: 1 MGRLLRAARLPPLLSPLLLLLVGGAFLGACVAGSDEPGPEGLTSTSLLDLLLPTGLEPLD 60
Query: 61 SEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVF 120
SEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVF
Sbjct: 61 SEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVF 120
Query: 121 PDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEK 180
PDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEK
Sbjct: 121 PDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEK 180
Query: 181 QEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMG 240
QEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMG
Sbjct: 181 QEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMG 240
Query: 241 PSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQH 300
PSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQH
Sbjct: 241 PSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQH 300
Query: 301 EEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLL 360
EEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLL
Sbjct: 301 EEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLL 360
Query: 361 EGQAAEAQSRIPWDSTQVICKDWSNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEV 420
EGQAAEAQSRIPWDSTQVICKDWSNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEV
Sbjct: 361 EGQAAEAQSRIPWDSTQVICKDWSNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEV 420
Query: 421 LPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQN 480
LPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQN
Sbjct: 421 LPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQN 480
Query: 481 YSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSHGEE 540
YSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSHGEE
Sbjct: 481 YSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSHGEE 540
Query: 541 LRFVENGCHDNPTLDVASDSQSEMQEKHPSLNGGGALNGPGSWGALMGGKRDPEDSDVFE 600
LRFVENGCHDNPTLDVASDSQSEMQEKHPSLNGGGALNGPGSWGALMGGKRDPEDSDVFE
Sbjct: 541 LRFVENGCHDNPTLDVASDSQSEMQEKHPSLNGGGALNGPGSWGALMGGKRDPEDSDVFE 600
Query: 601 EDTHL 605
EDTHL
Sbjct: 601 EDTHL 605
>gi|33598950 podocalyxin-like isoform 2 precursor [Homo sapiens]
Length = 526
Score = 70.5 bits (171), Expect = 4e-12
Identities = 100/433 (23%), Positives = 168/433 (38%), Gaps = 31/433 (7%)
Query: 178 VEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVES 237
+E + + + V S AKP + T KS H + D S+ E +
Sbjct: 120 IESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLT 179
Query: 238 SMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGA-AGL 296
+ P+ L PT+ P ++S + ++ V S T + +
Sbjct: 180 TPHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLPSSV 239
Query: 297 SGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLN 356
Q + + +TAPS E P T+ +P P M +P++A+
Sbjct: 240 ISQRTQQTSSQMPASSTAPSSQE--TVQPTSPATALRTPTLPETMSSSPTAASTTHR--- 294
Query: 357 QQLLEGQAAEAQSRIPWDSTQVICKDW-SNLAGKNYIILNMTENIDCEVFRQHRGPQLLA 415
+ +S C+D + + ++LN+T N C +L++
Sbjct: 295 ------YPKTPSPTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAGGASDE--KLIS 346
Query: 416 LVEEVLPRHGSGHHGAWHISLSKPSEKEQHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEE 475
L+ + + I L+ Q +++ + +P +DV L D L+E
Sbjct: 347 LICRAVKATFNPAQDKCGIRLASVPGS-QTVVVKEITIHTKLPAKDVYERLKDKWDELKE 405
Query: 476 IGIQNYSTTSSCQARASQVRSDYGTLFVVLVVIGAICIIIIALGLLYNCWQRRLPKLKHV 535
G+ + Q + + ++ +V A ++++A LY C +RL + K
Sbjct: 406 AGVSDMKLGD--QGPPEEAEDRFSMPLIITIVCMASFLLLVAA--LYGCCHQRLSQRKDQ 461
Query: 536 SH-GEELRFVENGCHDNPTLDVASDSQSEMQEKH-PSLNGGGALNGPGSWGALMGG-KRD 592
EEL+ VENG HDNPTL+V ++ SEMQEK SLNG SW + +D
Sbjct: 462 QRLTEELQTVENGYHDNPTLEV-METSSEMQEKKVVSLNG----ELGDSWIVPLDNLTKD 516
Query: 593 PEDSDVFEEDTHL 605
D EEDTHL
Sbjct: 517 DLDE---EEDTHL 526
>gi|66277202 podocalyxin-like isoform 1 precursor [Homo sapiens]
Length = 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 107/465 (23%), Positives = 175/465 (37%), Gaps = 63/465 (13%)
Query: 178 VEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVES 237
+E + + + V S AKP + T KS H + D S+ E +
Sbjct: 120 IESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLT 179
Query: 238 SMGPSLLL---------PSVTPTTVTPGDQDSTSQEAEATVLPA---------------- 272
+ P+ L P TPT+ S + +P
Sbjct: 180 TPHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLLETV 239
Query: 273 ------AGLGV--EFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDED 324
AGL + + P AS+ A A+ + Q + + +TAPS E
Sbjct: 240 FHHVSQAGLELLTSGDLPTLASQSAGITASSVISQRTQQTSSQMPASSTAPSSQE--TVQ 297
Query: 325 PLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQSRIPWDSTQVICKDW- 383
P T+ +P P M +P++A+ + +S C+D
Sbjct: 298 PTSPATALRTPTLPETMSSSPTAASTTHR---------YPKTPSPTVAHESNWAKCEDLE 348
Query: 384 SNLAGKNYIILNMTENIDCEVFRQHRGPQLLALVEEVLPRHGSGHHGAWHISLSKPSEKE 443
+ + ++LN+T N C +L++L+ + + I L+
Sbjct: 349 TQTQSEKQLVLNLTGNTLCAGGASDE--KLISLICRAVKATFNPAQDKCGIRLASVPGS- 405
Query: 444 QHLLMTLVGEQGVVPTQDVLSMLGDIRRSLEEIGIQNYSTTSSCQARASQVRSDYGTLFV 503
Q +++ + +P +DV L D L+E G+ + Q + + +
Sbjct: 406 QTVVVKEITIHTKLPAKDVYERLKDKWDELKEAGVSDMKLGD--QGPPEEAEDRFSMPLI 463
Query: 504 VLVVIGAICIIIIALGLLYNCWQRRLPKLKHVSH-GEELRFVENGCHDNPTLDVASDSQS 562
+ +V A ++++A LY C +RL + K EEL+ VENG HDNPTL+V ++ S
Sbjct: 464 ITIVCMASFLLLVAA--LYGCCHQRLSQRKDQQRLTEELQTVENGYHDNPTLEV-METSS 520
Query: 563 EMQEKH-PSLNGGGALNGPGSWGALMGG-KRDPEDSDVFEEDTHL 605
EMQEK SLNG SW + +D D EEDTHL
Sbjct: 521 EMQEKKVVSLNG----ELGDSWIVPLDNLTKDDLDE---EEDTHL 558
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 65.1 bits (157), Expect = 2e-10
Identities = 66/205 (32%), Positives = 92/205 (44%), Gaps = 24/205 (11%)
Query: 40 EGLTSTSLLDLLLPTGLEPLDSEEPSETMGLGAG----LGAPGSGFPSEENEESRILQPP 95
+G+ +TSLL+L E L E+ + G G L G SEE E+ +QP
Sbjct: 161 QGIIATSLLNLG-QIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQP- 218
Query: 96 QYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPP 155
E+ EE+ + + + + + P E A S E + Q L + + E
Sbjct: 219 ----EDAEEVVEVTTE---RSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEE-- 269
Query: 156 WHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQV---RDFSLTSSS 212
EEEE+EEEEEE E+EE E++EEEEEEE +EEA P V D S TS+
Sbjct: 270 ------EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQ 323
Query: 213 QTPGATKSRHEDSGDQASSGVEVES 237
+ P + S VEV S
Sbjct: 324 KAPELRGPESPSPKPEYSVIVEVRS 348
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 62.8 bits (151), Expect = 9e-10
Identities = 87/352 (24%), Positives = 124/352 (35%), Gaps = 46/352 (13%)
Query: 50 LLLPTGLEPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSS 109
+++P GL PL PS G+ P PP EE EEL +
Sbjct: 789 VIVPEGLPPLPPPPPS------------GATPPPIAPTGPPTASPPVPAKEEPEELPAAP 836
Query: 110 LDLGPTADYVFP-----DLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEE 164
L P P L E T P L L +N+ EEE
Sbjct: 837 GPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEE 896
Query: 165 EEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHED 224
EEEEEEEE E+E+ E++EE+EEE +EE + + + + + E+
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEE 956
Query: 225 SGDQ-----ASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEF 279
+ ++G EVE P LP P +P E E P GL +E
Sbjct: 957 LEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP---PKVQPEPE----PEPGLLLEV 1009
Query: 280 EAPQEASEEATAGAAGLSGQHEEVPALPSFPQ--------TTAPSGAEHPDEDPLGSRTS 331
E P E A L+ + ALPS + P E +E+P T
Sbjct: 1010 EEPGTEEERGADTAPTLAPE-----ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTL 1064
Query: 332 ASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQSRIPWDSTQVICKDW 383
G ++ P T +E++ + AEA D T + D+
Sbjct: 1065 LEEETEDGSDKVQPPPETPAEEEMETE----TEAEALQEKEQDDTAAMLADF 1112
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 57.4 bits (137), Expect = 4e-08
Identities = 50/145 (34%), Positives = 69/145 (47%), Gaps = 33/145 (22%)
Query: 57 EPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGPTA 116
+ L+S+E SE+M L A + G P +E PP EEEE+ D+ LD
Sbjct: 456 QQLESKEVSESMELCAAVEVMEQGVPEKEET------PPPVEPEEEEDTEDAGLD----- 504
Query: 117 DYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKE 176
D+ E S E+T + + N V H+ +E EEEEEEEE E+E
Sbjct: 505 DW------EAMASDEETEKVEG-----------NKV----HIEVKENPEEEEEEEEEEEE 543
Query: 177 EVEKQEEEEEE-ELLPVNGSQEEAK 200
+ E +EEEEEE E G +E+ K
Sbjct: 544 DEESEEEEEEEGESEGSEGDEEDEK 568
Score = 33.1 bits (74), Expect = 0.76
Identities = 19/44 (43%), Positives = 27/44 (61%), Gaps = 5/44 (11%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNG-----SQEEAK 200
E + +EEE E+EK E +KQ+E+E +E L G SQ EA+
Sbjct: 373 EAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR 416
Score = 29.6 bits (65), Expect = 8.4
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSR 221
EEE ++ EEEER K E + + +EEE L +E K + ++ + TKS+
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKEEERLE-QEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 222 HE 223
E
Sbjct: 413 RE 414
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 56.6 bits (135), Expect = 6e-08
Identities = 51/171 (29%), Positives = 72/171 (42%), Gaps = 17/171 (9%)
Query: 142 LPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKP 201
L +P + V+P + EEEEEE+EEEE E EE E++EEEEEEE +EEA
Sbjct: 715 LTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774
Query: 202 QV---RDFSLTSSSQTPGATKS--RHEDSGDQASSGVEVESSMGPSLLLP--------SV 248
V S S + G+ +S R ++ + + S G + + S
Sbjct: 775 AVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSK 834
Query: 249 TPTTVTPGDQDSTSQEAEATVLP----AAGLGVEFEAPQEASEEATAGAAG 295
T V+PGD + AE P A L + E PQ + G
Sbjct: 835 TLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPG 885
Score = 43.5 bits (101), Expect = 6e-04
Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 18/198 (9%)
Query: 149 MNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSL 208
M L P + P + + +EEEE E+E+ E++EE+EEEE +EE + + +
Sbjct: 713 MLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772
Query: 209 TSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTT---VTPGDQDSTSQEA 265
++ R S + + + PS LL + + D D +E
Sbjct: 773 AAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEG 832
Query: 266 EAT-VLPAAGLGVEFEAPQEASEEATAGA-AGLSGQHEEVPALPSFPQTTAPSGAEHPDE 323
T VL + G + E + + G A L+ QHE PQ P+G++
Sbjct: 833 SKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHER-------PQ---PTGSQLDVS 882
Query: 324 DPLGSRTSA--SSPLAPG 339
+P G+ +S S P PG
Sbjct: 883 EP-GTLSSVLKSEPKPPG 899
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 55.5 bits (132), Expect = 1e-07
Identities = 71/270 (26%), Positives = 107/270 (39%), Gaps = 37/270 (13%)
Query: 121 PDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEE---EEEREKEE 177
P + KAGS + + P P +++ + + EEE++EE EE++E +
Sbjct: 254 PLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGND 313
Query: 178 VEKQEEEEE----EELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGV 233
E Q E E E LP+ PQ+ + +S SQTP S D+ D G
Sbjct: 314 AEAQRREIELLRREGELPLEELLRSLPPQLLE-GPSSPSQTP---SSHDSDTRDGPEEGA 369
Query: 234 EVESSMGPSLLLPSVTPTTVT----------PGDQDSTSQEAEA-----TVLPAAGLGVE 278
E E P +L P+ VT D++ T+ E EA T+ L E
Sbjct: 370 EEEP---PQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGE 426
Query: 279 FEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAP--SGAEHPDEDPLGSRTSASSPL 336
+ E SE A G + EE+ L + AP +E DED + + +S P
Sbjct: 427 VDHAMELSELAREGELSM----EEL--LQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPE 480
Query: 337 APGDMELTPSSATLGQEDLNQQLLEGQAAE 366
P + E P + Q D + E + E
Sbjct: 481 GPVEAEEPPQEDSSSQSDSVEDRSEDEEDE 510
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 30/233 (12%)
Query: 128 GSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEE---EEEEEEEEREKEEVEKQEEE 184
G+ E+ Q E+ PS + + N + PWH +EE EEE E+E + E+Q E
Sbjct: 368 GAEEEPPQVLEIKPPPSAVTQRN--KQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEG 425
Query: 185 EEEELLPVNGSQEEAKPQVRD-FSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSL 243
E + + ++ E + + + + + PG+ S ED + ++ + E
Sbjct: 426 EVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCE------- 478
Query: 244 LLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEV 303
P P +DS+SQ E E + + EE T+G S EE
Sbjct: 479 --PEGPVEAEEPPQEDSSSQSDSVEDRS------EDEEDEHSEEEETSG----SSASEES 526
Query: 304 PALPSFPQTTAPSGAEHPDEDPLG-----SRTSASSPLAPGDMELTPSSATLG 351
+ S + E ++D G +R S G TP TLG
Sbjct: 527 ESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGSGPPTPGPTTLG 579
Score = 37.4 bits (85), Expect = 0.040
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 34/153 (22%)
Query: 72 AGLGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLD-LGPTADYVFP--DLTEKAG 128
AG APGSG +E+ E+E + N S + GP P D + ++
Sbjct: 452 AGAYAPGSGSSEDED-------------EDEVDANSSDCEPEGPVEAEEPPQEDSSSQSD 498
Query: 129 SIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEE-- 186
S+ED S+ +E + + E EE E EE E+ + + + +++EE+++
Sbjct: 499 SVEDRSEDEE--------DEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFG 550
Query: 187 -EELLPVNGSQEEAKPQVRDFSLTSSSQTPGAT 218
E LL + Q EA S TPG T
Sbjct: 551 VEYLLARDEEQSEA-------DAGSGPPTPGPT 576
Score = 30.4 bits (67), Expect = 4.9
Identities = 38/173 (21%), Positives = 65/173 (37%), Gaps = 17/173 (9%)
Query: 149 MNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQ--EEEEEEELLPVNGSQEEAKPQVRDF 206
M L EP P EEEEE ++ +E+ E+EE++ ++ E ++ +F
Sbjct: 2212 MPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEF 2271
Query: 207 SLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAE 266
+ ++ + D+ S E E + L+ +TP +
Sbjct: 2272 NENDGFPAGEGEEAGRPGAEDEEMSRAEQEI----AALVEQLTPI-----------ERYA 2316
Query: 267 ATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAE 319
L A+ V E ++A E+ A L EEV LP + +G E
Sbjct: 2317 MKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDE 2369
>gi|38373682 pleckstrin homology domain containing family G member 5
isoform a [Homo sapiens]
Length = 1006
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 38/252 (15%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEE----ELLPVNGSQ 196
N + L ++ EPP P + EEEE+E+E E+EE E++EE E+ P +
Sbjct: 681 NAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK 740
Query: 197 EEAKPQVRDFSLTSSSQT-------PGATKSRHE-DSGDQASSGVEVESSMGPSLLLPSV 248
P + + S++T PG T S E DSG +S E S S P+
Sbjct: 741 SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTS 800
Query: 249 TPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS 308
+ P D S S ++ L L +F AP + E VP P
Sbjct: 801 ELLPLGPVDGRSCSMDSAYGTLSPTSL-QDFVAPGPMA--------------ELVPRAPE 845
Query: 309 FPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQ 368
P+ +P P L RT P + + S A+L QLL G
Sbjct: 846 SPRVPSP-----PPSPRLRRRTPVQLLSCPPHLLKSKSEASL------LQLLAGAGTHGT 894
Query: 369 SRIPWDSTQVIC 380
P S +C
Sbjct: 895 PSAPSRSLSELC 906
>gi|111154084 pleckstrin homology domain containing family G member
5 isoform b [Homo sapiens]
Length = 1083
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 38/252 (15%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEE----ELLPVNGSQ 196
N + L ++ EPP P + EEEE+E+E E+EE E++EE E+ P +
Sbjct: 758 NAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK 817
Query: 197 EEAKPQVRDFSLTSSSQT-------PGATKSRHE-DSGDQASSGVEVESSMGPSLLLPSV 248
P + + S++T PG T S E DSG +S E S S P+
Sbjct: 818 SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTS 877
Query: 249 TPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS 308
+ P D S S ++ L L +F AP + E VP P
Sbjct: 878 ELLPLGPVDGRSCSMDSAYGTLSPTSL-QDFVAPGPMA--------------ELVPRAPE 922
Query: 309 FPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQ 368
P+ +P P L RT P + + S A+L QLL G
Sbjct: 923 SPRVPSP-----PPSPRLRRRTPVQLLSCPPHLLKSKSEASL------LQLLAGAGTHGT 971
Query: 369 SRIPWDSTQVIC 380
P S +C
Sbjct: 972 PSAPSRSLSELC 983
>gi|111154088 pleckstrin homology domain containing family G member
5 isoform a [Homo sapiens]
Length = 1006
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 38/252 (15%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEE----ELLPVNGSQ 196
N + L ++ EPP P + EEEE+E+E E+EE E++EE E+ P +
Sbjct: 681 NAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK 740
Query: 197 EEAKPQVRDFSLTSSSQT-------PGATKSRHE-DSGDQASSGVEVESSMGPSLLLPSV 248
P + + S++T PG T S E DSG +S E S S P+
Sbjct: 741 SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTS 800
Query: 249 TPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS 308
+ P D S S ++ L L +F AP + E VP P
Sbjct: 801 ELLPLGPVDGRSCSMDSAYGTLSPTSL-QDFVAPGPMA--------------ELVPRAPE 845
Query: 309 FPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQ 368
P+ +P P L RT P + + S A+L QLL G
Sbjct: 846 SPRVPSP-----PPSPRLRRRTPVQLLSCPPHLLKSKSEASL------LQLLAGAGTHGT 894
Query: 369 SRIPWDSTQVIC 380
P S +C
Sbjct: 895 PSAPSRSLSELC 906
>gi|111154080 pleckstrin homology domain containing family G member
5 isoform a [Homo sapiens]
Length = 1006
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 38/252 (15%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEE----ELLPVNGSQ 196
N + L ++ EPP P + EEEE+E+E E+EE E++EE E+ P +
Sbjct: 681 NAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK 740
Query: 197 EEAKPQVRDFSLTSSSQT-------PGATKSRHE-DSGDQASSGVEVESSMGPSLLLPSV 248
P + + S++T PG T S E DSG +S E S S P+
Sbjct: 741 SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTS 800
Query: 249 TPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS 308
+ P D S S ++ L L +F AP + E VP P
Sbjct: 801 ELLPLGPVDGRSCSMDSAYGTLSPTSL-QDFVAPGPMA--------------ELVPRAPE 845
Query: 309 FPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQ 368
P+ +P P L RT P + + S A+L QLL G
Sbjct: 846 SPRVPSP-----PPSPRLRRRTPVQLLSCPPHLLKSKSEASL------LQLLAGAGTHGT 894
Query: 369 SRIPWDSTQVIC 380
P S +C
Sbjct: 895 PSAPSRSLSELC 906
>gi|111154078 pleckstrin homology domain containing family G member
5 isoform c [Homo sapiens]
Length = 1062
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 38/252 (15%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEE----ELLPVNGSQ 196
N + L ++ EPP P + EEEE+E+E E+EE E++EE E+ P +
Sbjct: 737 NAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK 796
Query: 197 EEAKPQVRDFSLTSSSQT-------PGATKSRHE-DSGDQASSGVEVESSMGPSLLLPSV 248
P + + S++T PG T S E DSG +S E S S P+
Sbjct: 797 SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTS 856
Query: 249 TPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPS 308
+ P D S S ++ L L +F AP + E VP P
Sbjct: 857 ELLPLGPVDGRSCSMDSAYGTLSPTSL-QDFVAPGPMA--------------ELVPRAPE 901
Query: 309 FPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQ 368
P+ +P P L RT P + + S A+L QLL G
Sbjct: 902 SPRVPSP-----PPSPRLRRRTPVQLLSCPPHLLKSKSEASL------LQLLAGAGTHGT 950
Query: 369 SRIPWDSTQVIC 380
P S +C
Sbjct: 951 PSAPSRSLSELC 962
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 55.1 bits (131), Expect = 2e-07
Identities = 88/387 (22%), Positives = 133/387 (34%), Gaps = 61/387 (15%)
Query: 32 AGSDEPGPEGLTSTSLLDLLLPTGLEPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRI 91
A + E E T ++ L G + +SE A A G P E ES+
Sbjct: 1906 AEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ- 1964
Query: 92 LQPPQYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNL 151
E EEE S D+ A V + E G + S+ E P + +
Sbjct: 1965 --------EAEEEAQPESEDV--EALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEE 2014
Query: 152 VEPPWH-----MPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDF 206
P P E EE +E E E +K E + Q E + E +EA+ +V++
Sbjct: 2015 EAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEA 2074
Query: 207 SLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSV-TPTT------------- 252
+ ++ E S GVE + G + + P T
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEA 2134
Query: 253 ------VTPGDQDSTSQEAEATVLPAAGLGVE--------------FEAPQEASEEATAG 292
P + +Q+AE P + G+E EAP EA EA
Sbjct: 2135 PEAEGEAQPESEGVEAQDAEGEAQPESE-GIEAQEAEEEAQPELEGVEAP-EAEGEAQPE 2192
Query: 293 AAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLGQ 352
+ G+ E A P AP E +P G T P A G+ + T G+
Sbjct: 2193 SEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET----PEAEGEAQPESEGETQGE 2248
Query: 353 EDLNQQLLEG-----QAAEAQSRIPWD 374
+ + Q+ G +A+E+ S +P D
Sbjct: 2249 KKGSPQVSLGDGQSEEASESSSPVPED 2275
Score = 52.0 bits (123), Expect = 2e-06
Identities = 63/235 (26%), Positives = 89/235 (37%), Gaps = 29/235 (12%)
Query: 162 EEEEEEEEEEEREKEEVEK------QEE---EEEEELLPVNGSQEEAKPQVRDFSLTSSS 212
E+E E + EE+R +E+ QEE EE +E G QEEA Q+ +
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEA-VQLEETKTEEGL 1331
Query: 213 QTPG-----ATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEA 267
Q G ++ E ++ + E+E + G L V V G + EA
Sbjct: 1332 QEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALE 1391
Query: 268 TVLPAAGLGVEFEA-PQEASEEATAGAAGLSG----QHEEVPALPSFPQTTAPSGAEHPD 322
L GL E QE SE ++ G Q EE + + G E P
Sbjct: 1392 EGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPT 1451
Query: 323 E--------DPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQS 369
E DP S + S L PG +E P + +GQE Q +G A + S
Sbjct: 1452 EPPSHLSETDPSASERQSGSQLEPG-LEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
Score = 46.6 bits (109), Expect = 7e-05
Identities = 85/324 (26%), Positives = 116/324 (35%), Gaps = 50/324 (15%)
Query: 63 EPSETMGLGAG--------LGAPGSGFPSEENEESRILQPPQYFWEEEEELNDSSLDLGP 114
E ET G G+G A G P + + I P E E E S G
Sbjct: 1799 ERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP-----EAEGEAQPESE--GV 1851
Query: 115 TADYVFPDLTEKAGSIEDTSQAQELPNLPSPL-PKMNLVEPP---WHMPPREE-----EE 165
A D E G + S+ E P P+ VE P W + P E E
Sbjct: 1852 EAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEA 1911
Query: 166 EEEEEEEREK-EEVEKQEEEEEE----ELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKS 220
E+E + E E E +E + E+E E E + +EA+ Q + S SQ A +
Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQE--AEEE 1969
Query: 221 RHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFE 280
+S D + VEVE+ P V + + QEAE P + GVE +
Sbjct: 1970 AQPESEDVEALEVEVETQEAEGEAQPE--SEDVEAPEAEGEMQEAEEEAQPESD-GVEAQ 2026
Query: 281 APQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGD 340
P+ EEA Q E A P AP E E A G+
Sbjct: 2027 -PKSEGEEAQEVEG--ETQKTEGDAQPESDGVEAPEAEEEAQE-------------AEGE 2070
Query: 341 MELTPSSATLGQEDLNQQLLEGQA 364
++ A ED++ Q EG+A
Sbjct: 2071 VQEAEGEAHPESEDVDAQEAEGEA 2094
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/162 (32%), Positives = 73/162 (45%), Gaps = 29/162 (17%)
Query: 161 REEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKS 220
++EEEEEEEEEE E+EE E++E EEEEE LP PQ SS+T G+
Sbjct: 1130 QQEEEEEEEEEEEEEEEEEEEEAEEEEEELP---------PQY------FSSETSGSCAL 1174
Query: 221 RHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAG-LGVEF 279
E+ +E + L S + P +Q+S + + + P G LG +
Sbjct: 1175 NPEEV-------LEQPQPLSFGHLEGSRQGSQSVPAEQESFALHSSDFLPPIRGHLGSQ- 1226
Query: 280 EAPQEASEEATAGAAGL---SGQHEEVPALPSFPQTTAPSGA 318
P++A G GL SGQ A F + PSGA
Sbjct: 1227 --PEQAQPPCYYGIGGLWRTSGQEATESAKQEFQHFSPPSGA 1266
>gi|38372931 brevican isoform 2 [Homo sapiens]
Length = 671
Score = 52.8 bits (125), Expect = 9e-07
Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 43/247 (17%)
Query: 130 IEDTSQAQELPNLPSPLPKMNL-VEPPWHMPPR---EEEEEEEEEEEREKEEVEKQEEEE 185
+ED P P+ P+ L E +PP EEE + EEEE+ ++E EK+EEEE
Sbjct: 411 MEDGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEE 470
Query: 186 EEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKS------RHEDSGDQASSGV------ 233
EEE+ ++EA ++ S +PG S E+S QA +
Sbjct: 471 EEEV------EDEAL-----WAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGA 519
Query: 234 ------EVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASE 287
E E+S P + P T T TP +++ S + +T++ A +G P+ +
Sbjct: 520 SPLPDGESEASRPPRVHGPP-TETLPTPRERNLAS-PSPSTLVEAREVGEATGGPELSG- 576
Query: 288 EATAGAAGLSGQHEEVPALPSFPQTTAPSGA---EHPDEDPLGSRTSASSPLAPGDMELT 344
G + +G E P+L P T AP G E P ED G RT+ + L
Sbjct: 577 -VPRGESEETGSSEGAPSL--LPATRAPEGTRELEAPSEDNSG-RTAPAGTSVQAQPVLP 632
Query: 345 PSSATLG 351
SA+ G
Sbjct: 633 TDSASRG 639
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 52.8 bits (125), Expect = 9e-07
Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 43/247 (17%)
Query: 130 IEDTSQAQELPNLPSPLPKMNL-VEPPWHMPPR---EEEEEEEEEEEREKEEVEKQEEEE 185
+ED P P+ P+ L E +PP EEE + EEEE+ ++E EK+EEEE
Sbjct: 411 MEDGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEE 470
Query: 186 EEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKS------RHEDSGDQASSGV------ 233
EEE+ ++EA ++ S +PG S E+S QA +
Sbjct: 471 EEEV------EDEAL-----WAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGA 519
Query: 234 ------EVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASE 287
E E+S P + P T T TP +++ S + +T++ A +G P+ +
Sbjct: 520 SPLPDGESEASRPPRVHGPP-TETLPTPRERNLAS-PSPSTLVEAREVGEATGGPELSG- 576
Query: 288 EATAGAAGLSGQHEEVPALPSFPQTTAPSGA---EHPDEDPLGSRTSASSPLAPGDMELT 344
G + +G E P+L P T AP G E P ED G RT+ + L
Sbjct: 577 -VPRGESEETGSSEGAPSL--LPATRAPEGTRELEAPSEDNSG-RTAPAGTSVQAQPVLP 632
Query: 345 PSSATLG 351
SA+ G
Sbjct: 633 TDSASRG 639
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 129 SIEDTSQAQELP-NLPSP----LPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEE 183
+I D +++ LP +LP+P L + +PP P EEEEEEEEEEE E E E++EE
Sbjct: 275 AIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE--EEEEE 332
Query: 184 EEEEELLPVNGSQEEAKPQVRD 205
E+ EE P + A P D
Sbjct: 333 EDSEEAPPPLSPPQPASPAEED 354
Score = 35.0 bits (79), Expect = 0.20
Identities = 50/200 (25%), Positives = 72/200 (36%), Gaps = 37/200 (18%)
Query: 167 EEEEEEREKEEVEKQEEEEEEELLPVNGSQE-----EAKPQVRDFSLTSSSQTPGATKSR 221
+EE E+ E+E E+ ++ EE+L QE +A ++ D + S T T
Sbjct: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239
Query: 222 HEDSGDQASSGVEVESSMGPSLLLPSVTPTTVT-------PGDQDSTSQEAEATVLPAAG 274
+ GD A S E ++ LL T T T +D EA T LPA
Sbjct: 240 LDTDGDGALSEAEAQA------LLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA-- 291
Query: 275 LGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASS 334
A L+ EE P +PS P E +E+ S
Sbjct: 292 ----------------PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDS 335
Query: 335 PLAPGDMELTPSSATLGQED 354
AP + P A+ +ED
Sbjct: 336 EEAPPPLS-PPQPASPAEED 354
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/347 (23%), Positives = 127/347 (36%), Gaps = 56/347 (16%)
Query: 60 DSEEPSETMGL--GAGLGAPGSGFPSEENEESRI----LQPPQYFWEEEEELNDSSLDLG 113
+S EP E GL GA + G E + ++ LQ PQ E E L + D+
Sbjct: 1015 ESPEPKEQRGLVEGASVKGGAEGLQDPEGQSQQVGAPGLQAPQGLPEAIEPLVED--DVA 1072
Query: 114 PTADYVFPD--LTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEE 171
P D P+ L + E + A+ P P + + P H+ E E EEE
Sbjct: 1073 PGGDQASPEVMLGSEPAMGESAAGAE-----PGPGQGVGGLGDPGHLTREEVMEPPLEEE 1127
Query: 172 EREKEEVEKQEEEEEE---------ELLPVNGSQEEAKPQVRDFSLTSSSQTP-GATKSR 221
E + V+ E ++ E + G + R+ S ++ P GA ++
Sbjct: 1128 SLEAKRVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPREGREESEAEAPRGAEEAF 1187
Query: 222 HEDS----GDQASS-----GVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPA 272
++ G A S E E + P L+ PS T TP +D+ + +A
Sbjct: 1188 PAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPS---PTYTPILEDAPGPQPQAEGSQE 1244
Query: 273 AGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSA 332
A GV+ A E+ G SG+ +P PQ E +ED LG
Sbjct: 1245 ASWGVQGRAEALGKVESEQEELG-SGE------IPEGPQEEGEESREESEEDELGETLPD 1297
Query: 333 SSPLA------------PGDMELTPSSATLGQEDLNQQLLEGQAAEA 367
S+PL P + P G+E + +L + EA
Sbjct: 1298 STPLGFYLRSPTSPRWDPTGEQRPPPQGETGKEGWDPAVLASEGLEA 1344
Score = 37.4 bits (85), Expect = 0.040
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 29/303 (9%)
Query: 35 DEPGPEGLTSTSLLDLLLPTGLEPLDSEEPSETMGLGAGLGAPGSGFPSEENEESRILQP 94
D PGP+ S G + SE LG+G G P EE EESR
Sbjct: 1231 DAPGPQPQAEGSQEASWGVQGRAEALGKVESEQEELGSGEIPEG---PQEEGEESREES- 1286
Query: 95 PQYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEP 154
EE+EL ++ D P Y+ + + + + L
Sbjct: 1287 ------EEDELGETLPDSTPLGFYLRSPTSPRWDPTGEQRPPPQGETGKEGWDPAVLASE 1340
Query: 155 PWHMPPREEEEEEEEEEEREKEEVEKQEEEE---EEELLP-VNGSQEEAKPQVRDFSLTS 210
PP E+EE EE EEE ++ +E E+ E LP V G E QV L
Sbjct: 1341 GLEAPPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLLLDP 1400
Query: 211 SSQTPGATK---SRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEA 267
++ + E+SG++ E G P ++V S+SQ E
Sbjct: 1401 AAWDRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGPG---SSVGSLQALSSSQRGEF 1457
Query: 268 TVLPAAGLGVEFE---------APQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGA 318
+ + V ++ AP+ A E + +A SG EE + + P
Sbjct: 1458 LESDSVSVSVPWDDSLRGAVAGAPKTALETESQDSAEPSGSEEESDPVSLEREDKVPGPL 1517
Query: 319 EHP 321
E P
Sbjct: 1518 EIP 1520
Score = 30.0 bits (66), Expect = 6.4
Identities = 53/241 (21%), Positives = 85/241 (35%), Gaps = 34/241 (14%)
Query: 156 WHMPPREEEEEEEEEEEREKEEVEK------QEE----EEEEELLPVNGSQEEAKPQVRD 205
W++ EE ++E +R EE E QE EEE + LP + + + V
Sbjct: 898 WNLENLRSPEEVDKESQRNLEEEENLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEK 957
Query: 206 FSLTSSSQTPGATKSRHEDSGD------QASSGVEVESSMGPSLLLPSVTPTTVTPGDQD 259
+ PG +ED + +G E G + T PG+
Sbjct: 958 DQELAQESPPGMAGVENEDEAELNLREQDGFTGKEEVVEQGEL----NATEEVWIPGEGH 1013
Query: 260 STSQEAEATVLPAAGLGVE-----FEAPQEASEEATAGAAGLSGQHEEVPAL-PSFPQTT 313
S E + G V+ + P+ S++ GA GL A+ P
Sbjct: 1014 PESPEPKEQRGLVEGASVKGGAEGLQDPEGQSQQ--VGAPGLQAPQGLPEAIEPLVEDDV 1071
Query: 314 APSGAEHPDEDPLGSRTSASSPLAPGDMELTPSSATLG------QEDLNQQLLEGQAAEA 367
AP G + E LGS + A + LG +E++ + LE ++ EA
Sbjct: 1072 APGGDQASPEVMLGSEPAMGESAAGAEPGPGQGVGGLGDPGHLTREEVMEPPLEEESLEA 1131
Query: 368 Q 368
+
Sbjct: 1132 K 1132
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 9/81 (11%)
Query: 129 SIEDTSQAQELP-NLPSPLPKMNLVEPPWHMPP-------REEEEEEEEEEEREKEEVEK 180
+I D +++ LP +LP+P +L EP PP EEEEEEEEEEE E+EE E+
Sbjct: 275 AIRDKYRSEALPTDLPAPSAP-DLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
Query: 181 QEEEEEEELLPVNGSQEEAKP 201
E + E+ P + ++E+ P
Sbjct: 334 DSEVQGEQPKPASPAEEDKMP 354
Score = 31.2 bits (69), Expect = 2.9
Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 36/170 (21%)
Query: 167 EEEEEEREKEEVEKQEEEEEEELLPVNGSQE-----EAKPQVRDFSLTSSSQTPGATKSR 221
+EE E+ E+E E+ ++ EE+L QE +A ++ D + S T T
Sbjct: 180 KEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPE 239
Query: 222 HEDSGDQASSGVEVESSMGPSLLLPSVTPTTVT-------PGDQDSTSQEAEATVLPAAG 274
+ GD A S E ++ LL T T T +D EA T LPA
Sbjct: 240 LDTDGDGALSEAEAQA------LLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPA-- 291
Query: 275 LGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDED 324
A L+ EE P +PS P E +E+
Sbjct: 292 ----------------PSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEE 325
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 49.3 bits (116), Expect = 1e-05
Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 19/117 (16%)
Query: 159 PPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGAT 218
P EE EEEEEEEE E+EE E++EEEEEEE E K L S
Sbjct: 458 PAEEEAEEEEEEEEAEEEEEEEEEEEEEEE-------DEGCK------GLFPSELDEELE 504
Query: 219 KSRHEDSGDQASSGVEVE-----SSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVL 270
HE+ G A S + + S+ S L+P+V T++ G ++S A + V+
Sbjct: 505 DRPHEEPGAAAGSSSKKDLALSNQSISNSPLMPNVL-QTLSRGTASTSSNSASSFVV 560
Score = 34.7 bits (78), Expect = 0.26
Identities = 34/105 (32%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 282 PQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRT------SASSP 335
PQ AS A +A PA PS P T E P PL +T A P
Sbjct: 2056 PQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLP 2115
Query: 336 LAPGDMELTPSS-ATLGQEDLNQQLLEGQAAEAQSRIPWDSTQVI 379
G +E P+ A L Q LN LL+ Q ++RI D +V+
Sbjct: 2116 PQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVL 2160
Score = 33.9 bits (76), Expect = 0.44
Identities = 54/267 (20%), Positives = 98/267 (36%), Gaps = 50/267 (18%)
Query: 135 QAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNG 194
Q Q+ P + P P PP P +++++ ++++ + +E EK + + E LPV
Sbjct: 3200 QQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEP-LPVPK 3258
Query: 195 SQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQAS-SGVEVESSMGPSLLLPSVTPTTV 253
++ P T+++ T A E + D A ++ + P+ LL S
Sbjct: 3259 KEKGEAP-------TATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYF 3311
Query: 254 TPGDQDSTSQEAEATV---------------------------LPAAGLGVEFEAPQEAS 286
PG + + + L L +++ Q++
Sbjct: 3312 VPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSL 3371
Query: 287 EEATAGAAGLSGQHEEVPAL----PSFPQTTAPSGAEHPDEDPLGSRTSASSPLAPGDME 342
+EA Q ++ + P QT P GA PD+DP A P + +
Sbjct: 3372 QEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDP------AKESPKPEEQK 3425
Query: 343 LTPSSATLGQEDLNQQLLEGQAAEAQS 369
TP + L +L E AE++S
Sbjct: 3426 NTPREVS----PLLPKLPEEPEAESKS 3448
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVR-----------DFSLTS 210
+EEE + EEEE E E+ E +EEEE LP G +PQVR FS
Sbjct: 1200 DEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRG-----RPQVRLPVKTRGKLSSSFSSRG 1254
Query: 211 SSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVL 270
Q PG SR + Q++ V S G SL + P T T + ++ +
Sbjct: 1255 QQQEPGRYPSRSQ----QSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGP 1310
Query: 271 PAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPD---EDPLG 327
A + VE +P+ G + E P P+F S + L
Sbjct: 1311 LQADVFVELLSPRRKRR----GRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLS 1366
Query: 328 SRTSASSPLAPGDMELTPSSATLGQEDLNQQ 358
+ S S PS TLG+ +Q
Sbjct: 1367 LQESESKRRCRKRQSPEPSPVTLGRRSSGRQ 1397
Score = 29.6 bits (65), Expect = 8.4
Identities = 16/45 (35%), Positives = 29/45 (64%), Gaps = 6/45 (13%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEE------EEEELLPVNGSQEEAK 200
E +++E+E++E+++EE++K EE EE+E L V +E K
Sbjct: 336 EAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVR-----------DFSLTS 210
+EEE + EEEE E E+ E +EEEE LP G +PQVR FS
Sbjct: 1232 DEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRG-----RPQVRLPVKTRGKLSSSFSSRG 1286
Query: 211 SSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVL 270
Q PG SR + Q++ V S G SL + P T T + ++ +
Sbjct: 1287 QQQEPGRYPSRSQ----QSTPKTTVSSKTGRSLRKINSAPPTETKSLRIASRSTRHSHGP 1342
Query: 271 PAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPD---EDPLG 327
A + VE +P+ G + E P P+F S + L
Sbjct: 1343 LQADVFVELLSPRRKRR----GRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLS 1398
Query: 328 SRTSASSPLAPGDMELTPSSATLGQEDLNQQ 358
+ S S PS TLG+ +Q
Sbjct: 1399 LQESESKRRCRKRQSPEPSPVTLGRRSSGRQ 1429
Score = 29.6 bits (65), Expect = 8.4
Identities = 16/45 (35%), Positives = 29/45 (64%), Gaps = 6/45 (13%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEE------EEEELLPVNGSQEEAK 200
E +++E+E++E+++EE++K EE EE+E L V +E K
Sbjct: 336 EAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 48.9 bits (115), Expect = 1e-05
Identities = 52/216 (24%), Positives = 90/216 (41%), Gaps = 19/216 (8%)
Query: 161 REEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKS 220
++E++++E E E+EK + ++ ++ + LP A P+ R + T+S +P +K+
Sbjct: 414 KKEKKDKERENEKEKSALARERSLKKRQSLP-------ASPRARLSASTASELSP-KSKA 465
Query: 221 RHEDSGDQASSGVEVESSMGPSLLLPSVTP----TTVTPGDQDSTSQEAEATVLPAAGLG 276
R S GP LP P TT +P + +EA+ + AAG
Sbjct: 466 RPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESP-SAAGPE 524
Query: 277 VEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPL 336
+ ++ + AS E + A P+ PQ P D L S + + P+
Sbjct: 525 DKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPV 584
Query: 337 APGDMELTPSSATLGQEDLNQQLLE--GQAAEAQSR 370
P P + T +E+ + L E QA E + R
Sbjct: 585 TPS----KPMAGTTDREEATRLLAEKRRQAREQRER 616
Score = 33.5 bits (75), Expect = 0.58
Identities = 58/279 (20%), Positives = 97/279 (34%), Gaps = 28/279 (10%)
Query: 53 PTGLEPLDSEEPSETMGLGAGLGAPGSGFP-----------SEENEESRILQPPQYFWEE 101
PT P + P+ET A L +P + P ++ E +R+L + E
Sbjct: 553 PTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQARE 612
Query: 102 EEELNDSSLDLGPTADYVFPD---LTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPWHM 158
+ E + L D + E E ++A+ + E +
Sbjct: 613 QREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERL 672
Query: 159 PPREEEEE--EEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPG 216
++EE E EE ER++ E EK +++E+E EE + R ++ + Q
Sbjct: 673 QKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQD 732
Query: 217 ATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLG 276
+ ++ S + VE S P L +V P + + E GL
Sbjct: 733 SKEANANGSSPEPVKAVEARS---PGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGL- 788
Query: 277 VEFEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAP 315
P A +E G SG +L P+T P
Sbjct: 789 ----QPLPAHQENGFSTNGPSGD----KSLSRTPETLLP 819
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEE------AKPQVRDFSLTSSSQTP 215
EEEEEEEEEEE E+EE E++EEEE+EE +G+Q + + + + S P
Sbjct: 300 EEEEEEEEEEEEEEEEEEEEEEEEDEE----SGNQSDRSGSSGRRKAKKKWRKDSPWVKP 355
Query: 216 GATKSRHEDSGDQASSGVEVESSMGPS 242
+ + E + GV S GPS
Sbjct: 356 SRKRRKREPPRAKEPRGVNGVGSSGPS 382
Score = 32.3 bits (72), Expect = 1.3
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSR 221
E E E+ E E+EE E++EEEEEEE +EE + + SS A K
Sbjct: 290 EVEALTEQLSEEEEEEEEEEEEEEEEE---EEEEEEEDEESGNQSDRSGSSGRRKAKKKW 346
Query: 222 HEDS 225
+DS
Sbjct: 347 RKDS 350
Score = 29.6 bits (65), Expect = 8.4
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSR 221
+ + E E E+ EE E++EEEEEEE +EE + + D + S G++ R
Sbjct: 286 DSKSEVEALTEQLSEEEEEEEEEEEEE-----EEEEEEEEEEEDEESGNQSDRSGSSGRR 340
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 48.5 bits (114), Expect = 2e-05
Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 15/186 (8%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFS-LTSSSQTPGATKS 220
EEE+E +EEE +E+E E++E E EE ++E A P+ S + +++P KS
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKS 532
Query: 221 RHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTS-------QEAEATVLPAA 273
++ + E + P+ P +P +++ S ++A++ A
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 274 GLGVEFEAPQEA----SEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSR 329
E ++P++A EEA + A S EE S + +P A+ P ++ S
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA---KSPAEVKSPEKAKSPTKEEAKSP 649
Query: 330 TSASSP 335
A SP
Sbjct: 650 EKAKSP 655
Score = 41.2 bits (95), Expect = 0.003
Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 30/178 (16%)
Query: 84 EENEESRILQPPQYFWEEE-------EELNDSSLDLGPTADYVFPDLTEKAGSIEDT--- 133
E+ +E ++ +PP+ EE+ EE DS + P + P + EK +
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Query: 134 -------SQAQELPNLPSPLPKMNL-VEPPWHMPPREEEEEEEEEEE----------REK 175
+A++ +P+P + VE P+E+ E ++E + EK
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 176 EEV--EKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASS 231
+E EK++ +EE+ P + EAK + D +L+ P A K+ S DQ S
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Score = 40.8 bits (94), Expect = 0.004
Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 28/213 (13%)
Query: 141 NLPSPLPKMNLVEPPWHMPPREEEE--------------EEEEEEEREKEEV---EKQEE 183
+LP LPK+ V H+ + EE+ EE+ EE + EEV E++E
Sbjct: 421 SLPEGLPKIPSVST--HIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 184 EEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSL 243
+EEE G +EEA+ + + + K ++A S E +S
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE- 537
Query: 244 LLPSVTPTTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEV 303
+ +P V ++ + + EA P A + EA A ++ A + + +
Sbjct: 538 ---AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 304 PALPSFPQTTAPSGAEHPDEDPLGSRTSASSPL 336
PA + +P A+ P ++ S A SP+
Sbjct: 595 PA-----EAKSPEKAKSPVKEEAKSPAEAKSPV 622
Score = 40.4 bits (93), Expect = 0.005
Identities = 52/256 (20%), Positives = 99/256 (38%), Gaps = 27/256 (10%)
Query: 84 EENEESRILQPPQYFWEEEEELNDSSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLP 143
E+ EE+++ + + EEE+E + + E+ G E+ ++ E
Sbjct: 459 EQTEETQVTE--EVTEEEEKEAKEE-------------EGKEEEGGEEEEAEGGEEETKS 503
Query: 144 SPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQV 203
P + E P +EE + E + EKEE + E + E +E P
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE 563
Query: 204 RDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQ 263
+++P K S ++A S + E+ P + V ++ +
Sbjct: 564 AKSPEKEEAKSPAEVK-----SPEKAKSPAKEEAKSPAEAKSPEKAKSPVK--EEAKSPA 616
Query: 264 EAEATVLPAAGLGVEFEAPQEA----SEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAE 319
EA++ V A E ++P++A EEA + S + EE + P ++ + A+
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS-PEKAKSPVKAEAK 675
Query: 320 HPDEDPLGSRTSASSP 335
P++ + A SP
Sbjct: 676 SPEKAKSPVKAEAKSP 691
Score = 36.6 bits (83), Expect = 0.069
Identities = 46/233 (19%), Positives = 89/233 (38%), Gaps = 19/233 (8%)
Query: 131 EDTSQAQELPNLPSPLPKMNLVEPPWHMPPREEEEEEEEEEEREKEEVEKQEEEEEEELL 190
E S A + P K + P P +E+ + E+E +KEEV+ +EEE+
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK--- 829
Query: 191 PVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPSLLLPSVTP 250
P +E + + ++ +T S+ E++ + + +VE P++ P
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK--E 887
Query: 251 TTVTPGDQDSTSQEAEATVLPAAGLGVEFEAPQEASEEATAGAAGLSGQHEEVPALPSFP 310
+ V +++ ++ T A VE + + E+ + P+ P+
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 311 QTTAP-------SGAEHPDEDPL-------GSRTSASSPLAPGDMELTPSSAT 349
+ AP A+ P+E P +T + P P + SS+T
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
Score = 35.0 bits (79), Expect = 0.20
Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 25/183 (13%)
Query: 159 PPREEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGAT 218
P +EE + E+ + EKEE + E+ + PV E P+ + + +++P
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKS----PVKA--EAKSPEKAKSPVKAEAKSPEKA 694
Query: 219 KS---RHEDSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAAGL 275
KS S ++A S V+ E + P V TP S +E
Sbjct: 695 KSPVKEEAKSPEKAKSPVK-EEAKSPEKAKSPVKEEAKTPEKAKSPVKE----------- 742
Query: 276 GVEFEAPQEASEEATAGAAGLSGQHEEVPALPS--FPQTTAPSGAEHPDEDPLGSRTSAS 333
E ++P++A A + + PA P P A+ P ++ + S A
Sbjct: 743 --EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 334 SPL 336
SPL
Sbjct: 801 SPL 803
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/119 (34%), Positives = 60/119 (50%), Gaps = 14/119 (11%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSR 221
++E EEE EEE E+EEVE++EEE EEE V EE + +V + L Q A ++
Sbjct: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEV----EEEEEEVVEEELVGEEQELEAPETF 73
Query: 222 HE-------DSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEATVLPAA 273
E D GD +V + S++ PS+T T V Q +TS E + P++
Sbjct: 74 SEEYLWKVTDIGDYDDDFPDVRPRLA-SIVSPSLTSTFVP--SQSATSTETPSASPPSS 129
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 48.5 bits (114), Expect = 2e-05
Identities = 23/36 (63%), Positives = 29/36 (80%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQE 197
EEEEEEEEE+E E+EE E++EEEEEEE G++E
Sbjct: 860 EEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/47 (51%), Positives = 31/47 (65%), Gaps = 5/47 (10%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSL 208
+ EEEEEEEEE+E+EE E+++EEEEEE +EE K SL
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEE-----EEEEEEKGNEEPLSL 899
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/47 (44%), Positives = 31/47 (65%)
Query: 162 EEEEEEEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSL 208
+EEEEEEEE+E E+EE E++EE+ EE L ++ + K + F L
Sbjct: 869 QEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLL 915
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/29 (62%), Positives = 24/29 (82%)
Query: 161 REEEEEEEEEEEREKEEVEKQEEEEEEEL 189
+EEEEEEEE+EE E+EE E++E+ EE L
Sbjct: 869 QEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897
>gi|7661690 coiled-coil domain containing 9 [Homo sapiens]
Length = 531
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 8/111 (7%)
Query: 140 PNLPSPLPKMNLVEPPW-----HMPPREEEEEEEEEEEREKEEVEKQEEEEE---EELLP 191
P P PK ++PP H PP +E EE E EE+ E E++ + EEEEE EE
Sbjct: 384 PTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDE 443
Query: 192 VNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSGDQASSGVEVESSMGPS 242
+Q+ P+ + S Q G S E + + G PS
Sbjct: 444 EEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPS 494
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/230 (26%), Positives = 90/230 (39%), Gaps = 29/230 (12%)
Query: 162 EEEEEE---EEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGAT 218
EE+E+E EE+E E+EE ++EEEEE++ + ++E++ D +L+ +S+
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGD 1093
Query: 219 KSRHE-----------DSGDQASSGVEVESSMGPSLLLPSVTPTTVTPGDQDSTSQEAEA 267
E S ++S E ESS S V +++ +E
Sbjct: 1094 SDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMV 1153
Query: 268 TVLPAAGLGVE-FEAP-QEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHP---D 322
A G E FE +EA+ A A G EEV +T A + E P D
Sbjct: 1154 AEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDI-----ETEAVAPEERPSMLD 1208
Query: 323 EDPLGSRTSASSPLAPGDMELTPSSATLGQEDLNQQLLEGQAAEAQSRIP 372
E PL P D P L QE E A E ++R P
Sbjct: 1209 EPPLPVGVE-----EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
Score = 38.1 bits (87), Expect = 0.024
Identities = 82/325 (25%), Positives = 115/325 (35%), Gaps = 37/325 (11%)
Query: 52 LPTGLE-PLDSEEPSETMGL---GAGLGAPGSGFPSEENEESRILQPPQYFWEEEEELND 107
LP G+E P DS EP E GL GA L +P P++E E L P E +
Sbjct: 1212 LPVGVEEPADSREPPEEPGLSQEGAMLLSPEP--PAKEVEARPPLSP--------ERAPE 1261
Query: 108 SSLDLGPTADYVFPDLTEKAGSIEDTSQAQELPNLPSPLPKMNLVEPPW-HMPPREEEEE 166
L++ P + P ++ P PSP P+ + +PP E+
Sbjct: 1262 HDLEVEPEPPMMLP------LPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAED 1315
Query: 167 EEEEEEREKEEVEKQEEEEEEELLPVNGSQEEAKPQVRDFSLTSSSQTPGATKSRHEDSG 226
+ K + E P G + SL SS Q PG+ S S
Sbjct: 1316 HPPHTPGLCGSLAKSQSTETVPATP--GGEPPLSGGSSGLSL-SSPQVPGSPFSYPAPSP 1372
Query: 227 DQASSGVE----VESSMGPSLLLPS---VTPTTVTP-GDQDSTSQEAEATVLPAAGLGVE 278
+S G+ + S P+ PS + P P G +D S + VL GL +
Sbjct: 1373 SLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLP 1432
Query: 279 FEAPQEASEEATAGAAGLSGQHEEVPALPSFPQTTAPSGAEHPDEDPLGSRTSASSPLAP 338
P A + +P L P + P + P S S S
Sbjct: 1433 LPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLS--LD 1490
Query: 339 GDMELTPSSATLGQEDLNQQLLEGQ 363
G + P+ A LG+E L LL GQ
Sbjct: 1491 GPLVRPPAGAALGRELL---LLPGQ 1512
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.130 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,390,519
Number of Sequences: 37866
Number of extensions: 1656435
Number of successful extensions: 45768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 784
Number of HSP's successfully gapped in prelim test: 766
Number of HSP's that attempted gapping in prelim test: 16255
Number of HSP's gapped (non-prelim): 12088
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.