Guide to the Human Genome
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Name: BCL2 Sequence: fasta or formatted (239aa) NCBI GI: 72198189
Description:

B-cell lymphoma protein 2 alpha isoform

Referenced in:

B cells
BCL2 Pathways, Caspases, and Programmed Cell Death
MicroRNAs
Ras

Other entries for this name:
alt prot [205aa] B-cell lymphoma protein 2 beta isoform
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.3         27           3
 C cysteine            0.8          2           1
 D aspartate           5.0         12           2
 E glutamate           4.2         10           2
 F phenylalanine       5.0         12           2
 G glycine             9.2         22           2
 H histidine           3.8          9           1
 I isoleucine          2.9          7           1
 K lysine              1.7          4           1
 L leucine             9.2         22           2
 M methionine          2.9          7           1
 N asparagine          2.5          6           1
 P proline             7.9         19           2
 Q glutamine           2.5          6           1
 R arginine            7.1         17           2
 S serine              6.3         15           2
 T threonine           5.0         12           1
 V valine              6.7         16           2
 W tryptophan          2.5          6           1
 Y tyrosine            3.3          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   B-cell lymphoma protein 2 alpha isoform 
BCL2                  0.814   B-cell lymphoma protein 2 beta isoform 
BCL2L1                0.323   BCL2-like 1 isoform 1 
BCL2L2                0.270   BCL2-like 2 protein 
BAK1                  0.091   BCL2-antagonist/killer 1 
LOC100289713          0.091   PREDICTED: hypothetical protein XP_002348091 
BCL2L1                0.082   BCL2-like 1 isoform 2 
BAX                   0.080   BCL2-associated X protein isoform alpha 
BCL2A1                0.078   BCL2-related protein A1 isoform 1 
BAX                   0.076   BCL2-associated X protein isoform delta 
BCL2A1                0.074   BCL2-related protein A1 isoform 2 
BAX                   0.070   BCL2-associated X protein isoform beta 
BAX                   0.070   BCL2-associated X protein isoform sigma 
MCL1                  0.068   myeloid cell leukemia sequence 1 isoform 1 
BOK                   0.049   BCL2-related ovarian killer 
SETMAR                0.036   SET domain and mariner transposase fusion 
TNK2                  0.032   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.032   tyrosine kinase, non-receptor, 2 isoform 2 
FOXI3                 0.030   forkhead box I3 
CDKN1C                0.025   cyclin-dependent kinase inhibitor 1C isoform b [Hom...
CDKN1C                0.025   cyclin-dependent kinase inhibitor 1C isoform b [Hom...
CDKN1C                0.025   cyclin-dependent kinase inhibitor 1C isoform a 
BAT2                  0.025   HLA-B associated transcript-2 
WNK2                  0.025   WNK lysine deficient protein kinase 2 
UNCX                  0.025   UNC homeobox 
KHDRBS2               0.023   KH domain-containing, RNA-binding, signal transduct...
MBD6                  0.023   methyl-CpG binding domain protein 6 
TAF4                  0.023   TBP-associated factor 4 
SRCAP                 0.023   Snf2-related CBP activator protein 
NACA                  0.023   nascent polypeptide-associated complex alpha subuni...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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