Search of human proteins with 13899338

Search of human proteins with 13899338

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13899338 activin beta E [Homo sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13899338 activin beta E [Homo sapiens]                             732   0.0  
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]          248   4e-66
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]      181   9e-46
gi|4504699 inhibin beta A precursor [Homo sapiens]                    171   9e-43
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...   100   3e-21
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...    99   7e-21
gi|110349792 growth differentiation factor 1 [Homo sapiens]            98   1e-20
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...    96   4e-20
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...    96   4e-20
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...    96   4e-20
gi|61835232 growth differentiation factor 7 preproprotein [Homo ...    96   5e-20
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...    95   1e-19
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...    93   3e-19
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]       90   3e-18
gi|10190670 growth differentiation factor 3 precursor [Homo sapi...    89   8e-18
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]              87   3e-17
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa...    86   5e-17
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...    86   6e-17
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap...    85   1e-16
gi|4507465 transforming growth factor, beta 3 [Homo sapiens]           84   1e-16
gi|4885259 myostatin [Homo sapiens]                                    83   3e-16
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...    82   9e-16
gi|222352098 nodal precursor [Homo sapiens]                            81   1e-15
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa...    81   1e-15
gi|63025222 transforming growth factor, beta 1 [Homo sapiens]          79   6e-15
gi|4826740 growth differentiation factor 10 precursor [Homo sapi...    75   9e-14
gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo ...    75   1e-13
gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo sa...    75   1e-13
gi|7705308 growth differentiation factor 2 [Homo sapiens]              73   4e-13
gi|153792495 growth differentiation factor 15 [Homo sapiens]           70   2e-12

>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score =  732 bits (1890), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR 60
           MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR
Sbjct: 1   MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR 60

Query: 61  PRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHH 120
           PRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHH
Sbjct: 61  PRITHPPPQAALTRALRRLQPGSVAPGNGEEVISFATVTDSTSAYSSLLTFHLSTPRSHH 120

Query: 121 LYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRG 180
           LYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRG
Sbjct: 121 LYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRG 180

Query: 181 EKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTC 240
           EKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTC
Sbjct: 181 EKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTC 240

Query: 241 EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFS 300
           EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFS
Sbjct: 241 EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFS 300

Query: 301 LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350
           LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
Sbjct: 301 LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350


>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score =  248 bits (634), Expect = 4e-66
 Identities = 154/357 (43%), Positives = 206/357 (57%), Gaps = 28/357 (7%)

Query: 9   WLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPRITHPPP 68
           +L+L    V     G  CP+CGG  L  +++R L+L+LAK+ ILD LHLT RP +  P  
Sbjct: 9   FLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVS 68

Query: 69  QAALTRALRRLQ---PGSVAPGNGE---EVISFATVTDSTSAYSSLLTFHLSTPRS---H 119
           +AAL  AL+ L     G++   N E   E+ISFA  T  ++   + L FH S+ R+    
Sbjct: 69  RAALRTALQHLHGVPQGALLEDNREQECEIISFAE-TGLSTINQTRLDFHFSSDRTAGDR 127

Query: 120 HLYHARLWLHV-LPT-LPGTLCLRIFRWGPRRRRQGSRTLLAEH--HITNLGWHTLTLPS 175
            +  A L   V LP+    TL +R+   GP      + TL  ++   +   GWH L L  
Sbjct: 128 EVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNT---NLTLATQYLLEVDASGWHQLPLGP 184

Query: 176 SGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARR 235
                   G L L+L    LEG      Q   +L  A H+ PF+  ++R    G  +  R
Sbjct: 185 EAQAACSQGHLTLEL---VLEGQ---VAQSSVILGGAAHR-PFVAARVRVG--GKHQIHR 235

Query: 236 RTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFH 295
           R   C+  + +CCR++ +VDF+E+GW DWI+QPEGY +N+C GQCP H+AG PGIAASFH
Sbjct: 236 RGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFH 295

Query: 296 SAVFSLLKANNP--WPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350
           +AV +LLKAN         SCCVPTARRPLSLLY D + N+VKTD+PDMVVEACGCS
Sbjct: 296 TAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score =  181 bits (459), Expect = 9e-46
 Identities = 126/367 (34%), Positives = 182/367 (49%), Gaps = 46/367 (12%)

Query: 21  GTGSVCPSCGGSKLAPQAERAL--VLELAKQQILDGLHLTSRPRITHPPPQAALTRALRR 78
           G+   C SCGG +   +  R     LE  K+ IL  L +  RP ITH  P+AA+  ALR+
Sbjct: 50  GSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRK 109

Query: 79  LQPGSV---------------APG-NGEE----VISFATVTDSTSAYSSLLTFHLSTPRS 118
           L  G V               +PG +G+E    +ISFA  TD  ++    L F +S   +
Sbjct: 110 LHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAE-TDGLASSRVRLYFFISNEGN 168

Query: 119 HHLY--HARLWLHVLPTLPGTLCLRIFRWGPRRRRQ----------GSRTLLAEHHIT-- 164
            +L+   A LWL+ L  LP  L       G RR+ +          G R  + E  +   
Sbjct: 169 QNLFVVQASLWLY-LKLLPYVL-----EKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLK 222

Query: 165 NLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIR 224
             GWHT  L  +     + G  +L LD +  +    +   P  +       +PF+ ++ R
Sbjct: 223 RSGWHTFPLTEAIQALFERGERRLNLDVQ-CDSCQELAVVPVFVDPGEESHRPFVVVQAR 281

Query: 225 ANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHL 284
             +    R R+R   C+  T LCCR+  ++DF+ +GW DWI+ P GY  NYC G CP +L
Sbjct: 282 LGD-SRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYL 340

Query: 285 AGSPGIAASFHSAVFSLLKANNPWPAS-TSCCVPTARRPLSLLYLDHNGNVVKTDVPDMV 343
           AG PG A+SFH+AV +  +     P +  SCC+PT    +S+LY D   N+VK DVP+M+
Sbjct: 341 AGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMI 400

Query: 344 VEACGCS 350
           VE CGC+
Sbjct: 401 VEECGCA 407


>gi|4504699 inhibin beta A precursor [Homo sapiens]
          Length = 426

 Score =  171 bits (433), Expect = 9e-43
 Identities = 127/420 (30%), Positives = 196/420 (46%), Gaps = 83/420 (19%)

Query: 10  LVLLWALVRAQGT-GSV-------CPSCGGSKL---APQAERALVLELAKQQILDGLHLT 58
           L   W +VR+  T GS        CPSC  + L    P ++  +V E  K+ IL+ LHL 
Sbjct: 11  LASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLK 69

Query: 59  SRPRITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVTDSTSAYSSLLTFHL 113
            RP +T P P+AAL  A+R+L  G V   NG     +++   A + +     S ++TF  
Sbjct: 70  KRPDVTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMNELMEQTSEIITFAE 128

Query: 114 STPRSHHLY--------------HARLWLHV-LPTLPGT---LCLRIFRWGPRRRRQGS- 154
           S      L+               A +WL + +P    T   + +R+F+   ++  QGS 
Sbjct: 129 SGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQ--QQKHPQGSL 186

Query: 155 ----------------RTLLAEHHIT--NLGWHTLTLPSS--GLRGEKSGVLKLQLDCRP 194
                             LL+E  +      WH   + SS   L  +    L +++ C  
Sbjct: 187 DTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQ 246

Query: 195 LE--GNSTVTGQPRRLLDTAGH--------------------QQPFLELKIRANEPGAGR 232
            +  G S V    ++  +  G                      +PFL L+ R +E    R
Sbjct: 247 CQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHR 306

Query: 233 ARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAA 292
            RRR   C+    +CC++  +V F+++GW DWI+ P GY  NYC G+CP H+AG+ G + 
Sbjct: 307 RRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSL 366

Query: 293 SFHSAVFS--LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350
           SFHS V +   ++ ++P+    SCCVPT  RP+S+LY D   N++K D+ +M+VE CGCS
Sbjct: 367 SFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 426


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score = 99.8 bits (247), Expect = 3e-21
 Identities = 64/170 (37%), Positives = 84/170 (49%), Gaps = 10/170 (5%)

Query: 181 EKSGVLKLQLDC-RPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPT 239
           EK GV K  +   R L  +     Q R LL T GH      L  R       + R+R  +
Sbjct: 235 EKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKS 294

Query: 240 CEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVF 299
                  C R   YVDF ++GW DWI+ P GY   YC G+CP  LA    + ++ H+ V 
Sbjct: 295 S------CKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADH--LNSTNHAIVQ 346

Query: 300 SLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           +L+ + N      +CCVPT    +S+LYLD N  VV  +  DMVVE CGC
Sbjct: 347 TLVNSVNS-KIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 395


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score = 98.6 bits (244), Expect = 7e-21
 Identities = 101/370 (27%), Positives = 144/370 (38%), Gaps = 69/370 (18%)

Query: 26  CPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPRITHPPPQAALTRA--------LR 77
           CP C    +  Q  R L LE  K QIL  L L   P I+    +  L +A        L 
Sbjct: 62  CPVC----VWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLH 117

Query: 78  RLQPGSVAP----------GNGEEVISFATVTD---STSAYSSLLTFHLSTPRSH-HLYH 123
             Q  ++ P             E VIS A  TD    T        FH S       +  
Sbjct: 118 DFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLK 177

Query: 124 ARLWLHVLPT-LPGTLCLRIFRWGPR------------RRRQGSRTLLAEHHITNLGWHT 170
           A+LW+++ P   P T+ L+I R  P             RR    R+L  E H  +  W +
Sbjct: 178 AQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQS 237

Query: 171 LTLPS---SGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANE 227
           +       S  R  +S    ++++     G          L   A    PF+EL++  N 
Sbjct: 238 IDFKQVLHSWFRQPQSN-WGIEINAFDPSGTDLAVTS---LGPGAEGLHPFMELRVLENT 293

Query: 228 PGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCP------ 281
             + R          +   CCR    VDF+  GW DWI+ P+ Y+ NYCSGQC       
Sbjct: 294 KRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGQCEYMFMQK 352

Query: 282 -PHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVP 340
            PH                 L++  NP  ++  CC PT   P+++LY +    ++   +P
Sbjct: 353 YPHT---------------HLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIP 397

Query: 341 DMVVEACGCS 350
            MVV+ CGCS
Sbjct: 398 GMVVDRCGCS 407


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 46/105 (43%), Positives = 62/105 (59%), Gaps = 2/105 (1%)

Query: 247 CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQC--PPHLAGSPGIAASFHSAVFSLLKA 304
           C  R  YV F+E+GW  W++ P G+  NYC GQC  P  L+GS G  A  H+ + +L+ A
Sbjct: 267 CRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNHAVLRALMHA 326

Query: 305 NNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
             P  A   CCVP    P+S+L+ D++ NVV     DMVV+ CGC
Sbjct: 327 AAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGC 371


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 71/211 (33%), Positives = 95/211 (45%), Gaps = 22/211 (10%)

Query: 156 TLLAEHHITNLGWHTLTLPSSGLRG--EKSGVLKLQLDCRPLEGNSTVTGQ----PRRLL 209
           T L  H++T   W T  +  + LR   EK     L ++   L    T  GQ     R L 
Sbjct: 202 TRLVHHNVTR--WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLP 259

Query: 210 DTAGHQQPFLELKIRANEPGAGRA--RRRTPTCEPA---------TPLCCRRDHYVDFQE 258
             +G+      L +     G G A  RRR     P             C R   YVDF +
Sbjct: 260 QGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSD 319

Query: 259 LGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPT 318
           +GW DWI+ P GYQ  YC G CP  LA    + ++ H+ V +L+ + N      +CCVPT
Sbjct: 320 VGWNDWIVAPPGYQAFYCHGDCPFPLADH--LNSTNHAIVQTLVNSVNS-SIPKACCVPT 376

Query: 319 ARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
               +S+LYLD    VV  +  +MVVE CGC
Sbjct: 377 ELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 71/211 (33%), Positives = 95/211 (45%), Gaps = 22/211 (10%)

Query: 156 TLLAEHHITNLGWHTLTLPSSGLRG--EKSGVLKLQLDCRPLEGNSTVTGQ----PRRLL 209
           T L  H++T   W T  +  + LR   EK     L ++   L    T  GQ     R L 
Sbjct: 202 TRLVHHNVTR--WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLP 259

Query: 210 DTAGHQQPFLELKIRANEPGAGRA--RRRTPTCEPA---------TPLCCRRDHYVDFQE 258
             +G+      L +     G G A  RRR     P             C R   YVDF +
Sbjct: 260 QGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSD 319

Query: 259 LGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPT 318
           +GW DWI+ P GYQ  YC G CP  LA    + ++ H+ V +L+ + N      +CCVPT
Sbjct: 320 VGWNDWIVAPPGYQAFYCHGDCPFPLADH--LNSTNHAIVQTLVNSVNS-SIPKACCVPT 376

Query: 319 ARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
               +S+LYLD    VV  +  +MVVE CGC
Sbjct: 377 ELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 71/211 (33%), Positives = 95/211 (45%), Gaps = 22/211 (10%)

Query: 156 TLLAEHHITNLGWHTLTLPSSGLRG--EKSGVLKLQLDCRPLEGNSTVTGQ----PRRLL 209
           T L  H++T   W T  +  + LR   EK     L ++   L    T  GQ     R L 
Sbjct: 202 TRLVHHNVTR--WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLP 259

Query: 210 DTAGHQQPFLELKIRANEPGAGRA--RRRTPTCEPA---------TPLCCRRDHYVDFQE 258
             +G+      L +     G G A  RRR     P             C R   YVDF +
Sbjct: 260 QGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSD 319

Query: 259 LGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPT 318
           +GW DWI+ P GYQ  YC G CP  LA    + ++ H+ V +L+ + N      +CCVPT
Sbjct: 320 VGWNDWIVAPPGYQAFYCHGDCPFPLADH--LNSTNHAIVQTLVNSVNS-SIPKACCVPT 376

Query: 319 ARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
               +S+LYLD    VV  +  +MVVE CGC
Sbjct: 377 ELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407


>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 57/160 (35%), Positives = 76/160 (47%), Gaps = 5/160 (3%)

Query: 190 LDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCR 249
           L   PL    T T  PR ++     ++  L     A   G G  R            C R
Sbjct: 295 LASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHG---RRGRSRCSR 351

Query: 250 RDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWP 309
           +  +VDF+ELGW DWI+ P  Y+  +C G C   L     +  + H+ + +LL +  P  
Sbjct: 352 KPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSH--LEPTNHAIIQTLLNSMAPDA 409

Query: 310 ASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           A  SCCVP    P+S+LY+D   NVV     DMVVEACGC
Sbjct: 410 APASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 44/103 (42%), Positives = 61/103 (59%), Gaps = 2/103 (1%)

Query: 247 CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANN 306
           C + + YV FQ+LGW+DWI+ P+GY  NYC G+C   L  +  + A+ H+ V +L+   N
Sbjct: 412 CRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPL--NAHMNATNHAIVQTLVHLMN 469

Query: 307 PWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           P      CC PT    +S+LY D N NV+     +MVV ACGC
Sbjct: 470 PEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 48/130 (36%), Positives = 70/130 (53%), Gaps = 10/130 (7%)

Query: 228 PGAGRARRRTPTC--------EPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQ 279
           P  GR RRRT           + +   C ++  +V+F+ELGW DWI+ P  Y+  +C G 
Sbjct: 327 PSPGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGV 386

Query: 280 CPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDV 339
           C   L     +  + H+ + +L+ + +P     SCCVPT   P+S+LY+D   NVV    
Sbjct: 387 CDFPLRSH--LEPTNHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQY 444

Query: 340 PDMVVEACGC 349
            DMVVE+CGC
Sbjct: 445 EDMVVESCGC 454


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 61/191 (31%), Positives = 89/191 (46%), Gaps = 30/191 (15%)

Query: 186 LKLQLDCRPLEGNSTVTGQPRRLLDTAGHQ--QPFLELKIRANE-----------PGAGR 232
           L LQL    L+G S +  +   L+   G Q  QPF+    +A E               +
Sbjct: 243 LGLQLSVETLDGQS-INPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQ 301

Query: 233 ARRRTPTCEPATPL--------------CCRRDHYVDFQELGWRDWILQPEGYQLNYCSG 278
            R +TP  + A  +              C + + YV F++LGW+DWI+ PEGY   YC G
Sbjct: 302 NRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEG 361

Query: 279 QCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD 338
           +C   L  +  + A+ H+ V +L+   NP      CC PT    +S+LY D + NV+   
Sbjct: 362 ECAFPL--NSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKK 419

Query: 339 VPDMVVEACGC 349
             +MVV ACGC
Sbjct: 420 YRNMVVRACGC 430


>gi|10190670 growth differentiation factor 3 precursor [Homo
           sapiens]
          Length = 364

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 41/104 (39%), Positives = 65/104 (62%), Gaps = 3/104 (2%)

Query: 246 LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305
           LC R   +++F++LGW  WI+ P+G+  NYC G+CP  L  S  + +S ++ + +L+ A 
Sbjct: 263 LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTIS--LNSSNYAFMQALMHAV 320

Query: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           +P     + C+PT   P+S+LY D+N NV+     DMVV+ CGC
Sbjct: 321 DP-EIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 246 LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305
           +C R + YV FQ+LGW DW++ P+GY   YC G+C   L     + A+ H+ + SL+   
Sbjct: 300 VCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSC--MNATNHAILQSLVHLM 357

Query: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
            P     +CC PT     S+LY D + NV+     +MVV+ACGC
Sbjct: 358 KPNAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
           sapiens]
          Length = 402

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 246 LCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305
           +C R + YV FQ+LGW DW++ P+GY   YC G+C   L     + A+ H+ + SL+   
Sbjct: 300 VCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSC--MNATNHAILQSLVHLM 357

Query: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
            P     +CC PT     S+LY D + NV+     +MVV+ACGC
Sbjct: 358 MPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 44/126 (34%), Positives = 69/126 (54%), Gaps = 10/126 (7%)

Query: 232 RARRRTPTC-----EPATPL---CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPH 283
           R +RR P        P+  L   C R+  +V+F+++GW DWI+ P  Y+  +C G C   
Sbjct: 377 RRKRRAPLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFP 436

Query: 284 LAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMV 343
           L     +  + H+ + +L+ + +P     +CCVPT   P+S+L++D   NVV     DMV
Sbjct: 437 LRSH--LEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMV 494

Query: 344 VEACGC 349
           VE+CGC
Sbjct: 495 VESCGC 500


>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
           sapiens]
          Length = 454

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 40/103 (38%), Positives = 59/103 (57%), Gaps = 2/103 (1%)

Query: 247 CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANN 306
           C + + YV F++LGW+DWI+ PEGY   YC G+C   L  +  + A+ H+ V +L+    
Sbjct: 353 CKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPL--NAHMNATNHAIVQTLVHLMF 410

Query: 307 PWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           P      CC PT    +S+LY D + NV+     +MVV +CGC
Sbjct: 411 PDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453


>gi|4507465 transforming growth factor, beta 3 [Homo sapiens]
          Length = 412

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 58/159 (36%), Positives = 82/159 (51%), Gaps = 19/159 (11%)

Query: 203 GQPRRLLDTAGHQQPFLELKI----RANEPGAGRARRR----TPTC-EPATPLCCRRDHY 253
           G   RL     H  P L L +    R + PG G  R++    T  C       CC R  Y
Sbjct: 262 GDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLY 321

Query: 254 VDF-QELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAST 312
           +DF Q+LGW+ W+ +P+GY  N+CSG C P+L      A + HS V  L    NP  +++
Sbjct: 322 IDFRQDLGWK-WVHEPKGYYANFCSGPC-PYLRS----ADTTHSTVLGLYNTLNPEASAS 375

Query: 313 SCCVPTARRPLSLLYLDHNGNVVKTD-VPDMVVEACGCS 350
            CCVP    PL++LY  + G   K + + +MVV++C CS
Sbjct: 376 PCCVPQDLEPLTILY--YVGRTPKVEQLSNMVVKSCKCS 412


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 90/339 (26%), Positives = 143/339 (42%), Gaps = 48/339 (14%)

Query: 44  LELAKQQILDGLHLTSRPRITHPPPQAALTRA--LRRL-----------QPGSVAPGN-- 88
           +E  K QIL  L L + P I+    +  L +A  LR L             GS+   +  
Sbjct: 53  IEAIKIQILSKLRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYH 112

Query: 89  --GEEVISFATVTD---STSAYSSLLTFHLSTPRSHH-LYHARLWLHVLPT-LPGTLCLR 141
              E +I+  T +D             F  S+   ++ +  A+LW+++ P   P T+ ++
Sbjct: 113 ATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQ 172

Query: 142 IFRW-GPRR---RRQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLDCRPLEG 197
           I R   P +   R  G R+L  + +     W ++ + +      K     L ++ + L+ 
Sbjct: 173 ILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDE 232

Query: 198 NS-----TVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPL-CCRRD 251
           N      T  G     L+      PFLE+K+  + P   R        E +T   CCR  
Sbjct: 233 NGHDLAVTFPGPGEDGLN------PFLEVKV-TDTPKRSRRDFGLDCDEHSTESRCCRYP 285

Query: 252 HYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAS 311
             VDF+  GW DWI+ P+ Y+ NYCSG+C              H A        NP  ++
Sbjct: 286 LTVDFEAFGW-DWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQA--------NPRGSA 336

Query: 312 TSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350
             CC PT   P+++LY +    ++   +P MVV+ CGCS
Sbjct: 337 GPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS 375


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 40/103 (38%), Positives = 54/103 (52%), Gaps = 2/103 (1%)

Query: 247 CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANN 306
           C R   Y+DF+E+GW  WI+ P GY+   C G C   LA    +  + H+ + +L+   N
Sbjct: 323 CKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEH--LTPTKHAIIQALVHLKN 380

Query: 307 PWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
              AS +CCVPT   P+S+LYLD      K     M V  CGC
Sbjct: 381 SQKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGC 423


>gi|222352098 nodal precursor [Homo sapiens]
          Length = 347

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 3/116 (2%)

Query: 234 RRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAAS 293
           R R       + LC +    VDF  +GW  WI+ P+ Y    C G+CP  +        +
Sbjct: 234 RHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEE--FHPT 291

Query: 294 FHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
            H+ + SLLK   P    ++CC P   +PLS+LY+D NG V+     DM+VE CGC
Sbjct: 292 NHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVD-NGRVLLDHHKDMIVEECGC 346


>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
           sapiens]
          Length = 472

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 44/116 (37%), Positives = 61/116 (52%), Gaps = 5/116 (4%)

Query: 235 RRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASF 294
           RR    EP    C RR   VDF ++GW +WI+ P+ +   YCSG C   +  S  +  S 
Sbjct: 360 RRKQWIEPRN--CARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKS--LKPSN 415

Query: 295 HSAVFSLLKANNPWPA-STSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           H+ + S+++A    P     CCVP     LS+L+ D N NVV    P+M VE+C C
Sbjct: 416 HATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCAC 471


>gi|63025222 transforming growth factor, beta 1 [Homo sapiens]
          Length = 390

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 56/162 (34%), Positives = 82/162 (50%), Gaps = 17/162 (10%)

Query: 198 NSTVTGQPRRLLDTAGHQQPFLELKI----RANEPGAGRARRRTPT--CEPATPL-CCRR 250
           N   TG+   L    G  +PFL L      RA    + R RR   T  C  +T   CC R
Sbjct: 237 NGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVR 296

Query: 251 DHYVDFQ-ELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWP 309
             Y+DF+ +LGW+ WI +P+GY  N+C G CP   +       + +S V +L   +NP  
Sbjct: 297 QLYIDFRKDLGWK-WIHEPKGYHANFCLGPCPYIWS-----LDTQYSKVLALYNQHNPGA 350

Query: 310 ASTSCCVPTARRPLSLLYLDHNGNVVKTD-VPDMVVEACGCS 350
           ++  CCVP A  PL ++Y  + G   K + + +M+V +C CS
Sbjct: 351 SAAPCCVPQALEPLPIVY--YVGRKPKVEQLSNMIVRSCKCS 390


>gi|4826740 growth differentiation factor 10 precursor [Homo
           sapiens]
          Length = 478

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 5/116 (4%)

Query: 235 RRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASF 294
           RR    EP   +C RR   VDF ++GW +WI+ P+ +   YC+G C         +  S 
Sbjct: 366 RRKQWDEPR--VCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGAC--EFPMPKIVRPSN 421

Query: 295 HSAVFSLLKANNPWPA-STSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
           H+ + S+++A    P     CCVP     L +L+LD N NVV    P+M V+ C C
Sbjct: 422 HATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCAC 477


>gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 10/106 (9%)

Query: 247 CCRRDHYVDFQ-ELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305
           CC R  Y+DF+ +LGW+ WI +P+GY  N+C+G C P+L  S     + HS V SL    
Sbjct: 345 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGAC-PYLWSSD----TQHSRVLSLYNTI 398

Query: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD-VPDMVVEACGCS 350
           NP  +++ CCV     PL++LY  + G   K + + +M+V++C CS
Sbjct: 399 NPEASASPCCVSQDLEPLTILY--YIGKTPKIEQLSNMIVKSCKCS 442


>gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 10/106 (9%)

Query: 247 CCRRDHYVDFQ-ELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKAN 305
           CC R  Y+DF+ +LGW+ WI +P+GY  N+C+G C P+L  S     + HS V SL    
Sbjct: 317 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGAC-PYLWSSD----TQHSRVLSLYNTI 370

Query: 306 NPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD-VPDMVVEACGCS 350
           NP  +++ CCV     PL++LY  + G   K + + +M+V++C CS
Sbjct: 371 NPEASASPCCVSQDLEPLTILY--YIGKTPKIEQLSNMIVKSCKCS 414


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 94/375 (25%), Positives = 141/375 (37%), Gaps = 70/375 (18%)

Query: 42  LVLELAKQQILDGLHLTSRP---RITHPPPQAALTRALRRLQPGSVAPGNG-------EE 91
           + LE  K   L  L+L+  P   +    PPQ  +    R     S  P +        E+
Sbjct: 57  MFLENVKVDFLRSLNLSGVPSQDKTRVEPPQYMIDLYNRYTSDKSTTPASNIVRSFSMED 116

Query: 92  VISFATVTDSTSAYSSLLTFHLSTPRSHHLYHARLWL------HVLPT--LPGTLCLRIF 143
            IS  T T+       +L F++S PR   +  A L L      HV P+  L G++ +   
Sbjct: 117 AISI-TATEDFPFQKHILLFNISIPRHEQITRAELRLYVSCQNHVDPSHDLKGSVVIYDV 175

Query: 144 RWGPRRRRQGS--RTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLK-------------- 187
             G       +  +T L    I + GW TL + S+  R  +S   K              
Sbjct: 176 LDGTDAWDSATETKTFLVSQDIQDEGWETLEVSSAVKRWVRSDSTKSKNKLEVTVESHRK 235

Query: 188 ----LQLDCRPLEGN-----------STVTGQPR-RLLDTAGHQQPFLELKIR---ANEP 228
               L +   P   N           S+ T + R  L +   H+Q  +  K+    + E 
Sbjct: 236 GCDTLDISVPPGSRNLPFFVVFSNDHSSGTKETRLELREMISHEQESVLKKLSKDGSTEA 295

Query: 229 G-------------AGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNY 275
           G             AG    R      A   C +    V+F+++GW  WI+ P+ Y+   
Sbjct: 296 GESSHEEDTDGHVAAGSTLARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYE 355

Query: 276 CSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLLYLDHNG-NV 334
           C G C   LA    +  + H+ V +L+    P     +CCVPT   P+S+LY D  G   
Sbjct: 356 CKGGCFFPLADD--VTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPT 413

Query: 335 VKTDVPDMVVEACGC 349
           +K     M V  CGC
Sbjct: 414 LKYHYEGMSVAECGC 428


>gi|153792495 growth differentiation factor 15 [Homo sapiens]
          Length = 308

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 47/149 (31%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 204 QPRRLLDTAGHQQPFLELKIRANEP-GAGRARRRTPTCEPATPLCCRRDHYV--DFQELG 260
           Q  +LL  +   +P LEL +R     G  RAR R     P  P  C R H V    ++LG
Sbjct: 165 QSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCPLGPGRCCRLHTVRASLEDLG 224

Query: 261 WRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTAR 320
           W DW+L P   Q+  C G CP         AA+ H+ + + L    P      CCVP + 
Sbjct: 225 WADWVLSPREVQVTMCIGACPSQFR-----AANMHAQIKTSLHRLKPDTVPAPCCVPASY 279

Query: 321 RPLSLLYLDHNGNVVKTDVPDMVVEACGC 349
            P+ L+     G  ++T   D++ + C C
Sbjct: 280 NPMVLIQKTDTGVSLQT-YDDLLAKDCHC 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,184,030
Number of Sequences: 37866
Number of extensions: 805755
Number of successful extensions: 2035
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1953
Number of HSP's gapped (non-prelim): 49
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.