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Search of human proteins with 13699830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
(581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 1177 0.0
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 1064 0.0
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 899 0.0
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 360 3e-99
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 350 2e-96
gi|11321565 matrilin 3 precursor [Homo sapiens] 311 1e-84
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 278 1e-74
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 213 4e-55
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 168 1e-41
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 149 7e-36
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 134 2e-31
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 134 3e-31
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 129 1e-29
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 121 2e-27
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 118 2e-26
gi|21359974 vitrin [Homo sapiens] 110 3e-24
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 109 6e-24
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 108 1e-23
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 108 2e-23
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 104 2e-22
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 103 3e-22
gi|205277471 cochlin precursor [Homo sapiens] 103 6e-22
gi|4758022 cochlin precursor [Homo sapiens] 103 6e-22
gi|40068485 von Willebrand factor A domain containing 1 isoform ... 102 7e-22
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 102 1e-21
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 99 1e-20
gi|19743803 fibulin 5 precursor [Homo sapiens] 98 2e-20
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 97 4e-20
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 96 9e-20
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 96 9e-20
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 1177 bits (3046), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240
Query: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL
Sbjct: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
Query: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360
CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN
Sbjct: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360
Query: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420
FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER
Sbjct: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420
Query: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480
GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY
Sbjct: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480
Query: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540
AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC
Sbjct: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540
Query: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581
ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 1064 bits (2751), Expect = 0.0
Identities = 540/581 (92%), Positives = 540/581 (92%), Gaps = 41/581 (7%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-------------------------- 214
Query: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL
Sbjct: 215 ---------------AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 259
Query: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360
CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN
Sbjct: 260 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 319
Query: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420
FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER
Sbjct: 320 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 379
Query: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480
GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY
Sbjct: 380 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 439
Query: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540
AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC
Sbjct: 440 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 499
Query: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581
ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 500 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 899 bits (2323), Expect = 0.0
Identities = 479/581 (82%), Positives = 483/581 (83%), Gaps = 82/581 (14%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC DL
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDL---------------------- 218
Query: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
C +D H C+ +CVS RC C EG LQ DG+S
Sbjct: 219 -------------CNGVD------HGCEFQCVSEGLSYRCLCPEGRQLQADGKS------ 253
Query: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360
CNRCREGHVDLVLLVDGSKSVRPQN
Sbjct: 254 -----------------------------------CNRCREGHVDLVLLVDGSKSVRPQN 278
Query: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420
FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER
Sbjct: 279 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 338
Query: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480
GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY
Sbjct: 339 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 398
Query: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540
AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC
Sbjct: 399 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 458
Query: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581
ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 459 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 499
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 360 bits (923), Expect = 3e-99
Identities = 180/419 (42%), Positives = 250/419 (59%), Gaps = 48/419 (11%)
Query: 207 LQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNH 265
L+ + CA +D CA G HGCEH CV+S S+ C C G++L++D ++CR D C +H
Sbjct: 516 LRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 266 SCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPE 325
C+H CV++ C C EG L DG+ C+ +D+C HGCE CV+ G SY C C E
Sbjct: 576 GCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSE 635
Query: 326 GRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVG 385
G L DG+ C +C EG +DLV ++DGSKS+ +NFE+VK+FV I+D L +SP+ RVG
Sbjct: 636 GFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVG 695
Query: 386 LVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 445
L+Q+S++V TEF L + +A ++K+AV ++YM +G+MTGLAL+HM E SF++ +GARP
Sbjct: 696 LLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL 755
Query: 446 ALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVS 505
+ VPR +VFTDGR+QDD+S WA++AK GI MYAVGVGKA+E EL+EIASEP H+
Sbjct: 756 STRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLF 815
Query: 506 YAPDFGTMTHLLENLRGSIC--------------------------------PEEGISAG 533
YA DF TM + E L+ IC E+ +
Sbjct: 816 YAEDFSTMDEISEKLKKGICEALEDSDGRQDSPAGELPKTVQQPTVQHRYLFEEDNLLRS 875
Query: 534 T---------------ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQL 577
T E C+CE+L+ FQ + LT L ++T R+E LEN+L
Sbjct: 876 TQKLSHSTKPSGSPLEEKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRL 934
Score = 320 bits (821), Expect = 2e-87
Identities = 150/319 (47%), Positives = 210/319 (65%)
Query: 20 QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
Q L C DLVF+IDSSRSV ++ +++F++ +L+ L++GP+ TRVG++QY
Sbjct: 43 QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
S V++ F L+ F R+ ++ERA++ + L+ GTMTGLAIQYA+N+AFS AEGARP E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
RV +IVTDGRPQD VAEVAA+AR GI I+A+GV + D +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222
Query: 200 DLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY 259
I+ FQ +LC +C+ H C H C+N PGSY C C+ G++L DQ +CR D
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Query: 260 CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSY 319
C+ +H+C+ CV+ PG C C G+ L DG+ C D C +HGCE +CV+ SY
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSY 342
Query: 320 RCLCPEGRQLQADGKSCNR 338
C C EG L D K+C +
Sbjct: 343 LCQCHEGFALNPDKKTCTK 361
Score = 169 bits (427), Expect = 8e-42
Identities = 81/188 (43%), Positives = 126/188 (67%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
+C GP+DLVFVID S+S+ FE ++QF+ G++ L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
LR F+ +DM++A+ + + +G+MTGLA+++ +F+ EGARP RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V+E A++A+A GI +YAVGV +A L+ +AS P ++H+F E F + E
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 828 EKLKKGIC 835
Score = 155 bits (393), Expect = 7e-38
Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C DLV ++D S+SV ++ VK F+ I+ FLD+ P+ TRVGL+Q+ S V+ EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L + +EV++AV + ++ GTMTGLA+++ + +FSEA+GARP NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
GR QD ++ AA+A++ GI+++A+GVG+ L+ I SEP E HV +F + L
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230
Query: 519 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 573
+ +C S L C + + LN Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Score = 142 bits (358), Expect = 8e-34
Identities = 60/127 (47%), Positives = 77/127 (60%)
Query: 212 RLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHEC 271
R A+D CA HGCEH CVN+ GSY C C GF L D+++C IDYC+ NH CQHEC
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHEC 376
Query: 272 VSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQA 331
V+T CHC +G L PD ++C+ + C GCE +CV+ SY C C G L
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 436
Query: 332 DGKSCNR 338
+GK+C+R
Sbjct: 437 NGKTCSR 443
Score = 134 bits (336), Expect = 3e-31
Identities = 62/148 (41%), Positives = 82/148 (55%), Gaps = 6/148 (4%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
F L + C ID CA HGC+H CVN+ SY CHC GF L D+++CR I+YC+
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLC 323
C+HECV+ C C G+ L P+G++C D C DHGCE C++ S+ C C
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Query: 324 PEGRQLQADGKSCNRCREGHVDLVLLVD 351
EG + D K+C+R VD LL D
Sbjct: 470 SEGFLINEDLKTCSR-----VDYCLLSD 492
Score = 128 bits (322), Expect = 1e-29
Identities = 53/123 (43%), Positives = 74/123 (60%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTP 275
+D CA+ HGCE C+N+ S+ C C GF++ +D ++C +DYC +H C++ CV+
Sbjct: 444 VDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMD 503
Query: 276 GGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKS 335
C C EGH L+ DG++C D C DHGCE CVS S+ C C EG L+ DGK+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKT 563
Query: 336 CNR 338
C R
Sbjct: 564 CRR 566
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 350 bits (898), Expect = 2e-96
Identities = 161/320 (50%), Positives = 221/320 (69%), Gaps = 1/320 (0%)
Query: 207 LQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNH 265
L+ + CA +D CA G HGCEH CV+S S+ C C G++L++D ++CR D C +H
Sbjct: 516 LRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDH 575
Query: 266 SCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPE 325
C+H CV++ C C EG L DG+ C+ +D+C HGCE CV+ G SY C C E
Sbjct: 576 GCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSE 635
Query: 326 GRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVG 385
G L DG+ C +C EG +DLV ++DGSKS+ +NFE+VK+FV I+D L +SP+ RVG
Sbjct: 636 GFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVG 695
Query: 386 LVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 445
L+Q+S++V TEF L + +A ++K+AV ++YM +G+MTGLAL+HM E SF++ +GARP
Sbjct: 696 LLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPL 755
Query: 446 ALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVS 505
+ VPR +VFTDGR+QDD+S WA++AK GI MYAVGVGKA+E EL+EIASEP H+
Sbjct: 756 STRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLF 815
Query: 506 YAPDFGTMTHLLENLRGSIC 525
YA DF TM + E L+ IC
Sbjct: 816 YAEDFSTMDEISEKLKKGIC 835
Score = 320 bits (821), Expect = 2e-87
Identities = 150/319 (47%), Positives = 210/319 (65%)
Query: 20 QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
Q L C DLVF+IDSSRSV ++ +++F++ +L+ L++GP+ TRVG++QY
Sbjct: 43 QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
S V++ F L+ F R+ ++ERA++ + L+ GTMTGLAIQYA+N+AFS AEGARP E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
RV +IVTDGRPQD VAEVAA+AR GI I+A+GV + D +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222
Query: 200 DLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY 259
I+ FQ +LC +C+ H C H C+N PGSY C C+ G++L DQ +CR D
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Query: 260 CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSY 319
C+ +H+C+ CV+ PG C C G+ L DG+ C D C +HGCE +CV+ SY
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSY 342
Query: 320 RCLCPEGRQLQADGKSCNR 338
C C EG L D K+C +
Sbjct: 343 LCQCHEGFALNPDKKTCTK 361
Score = 169 bits (427), Expect = 8e-42
Identities = 81/188 (43%), Positives = 126/188 (67%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
+C GP+DLVFVID S+S+ FE ++QF+ G++ L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
LR F+ +DM++A+ + + +G+MTGLA+++ +F+ EGARP RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V+E A++A+A GI +YAVGV +A L+ +AS P ++H+F E F + E
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 828 EKLKKGIC 835
Score = 155 bits (393), Expect = 7e-38
Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C DLV ++D S+SV ++ VK F+ I+ FLD+ P+ TRVGL+Q+ S V+ EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L + +EV++AV + ++ GTMTGLA+++ + +FSEA+GARP NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
GR QD ++ AA+A++ GI+++A+GVG+ L+ I SEP E HV +F + L
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230
Query: 519 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 573
+ +C S L C + + LN Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Score = 142 bits (358), Expect = 8e-34
Identities = 60/127 (47%), Positives = 77/127 (60%)
Query: 212 RLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHEC 271
R A+D CA HGCEH CVN+ GSY C C GF L D+++C IDYC+ NH CQHEC
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHEC 376
Query: 272 VSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQA 331
V+T CHC +G L PD ++C+ + C GCE +CV+ SY C C G L
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDP 436
Query: 332 DGKSCNR 338
+GK+C+R
Sbjct: 437 NGKTCSR 443
Score = 134 bits (336), Expect = 3e-31
Identities = 62/148 (41%), Positives = 82/148 (55%), Gaps = 6/148 (4%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
F L + C ID CA HGC+H CVN+ SY CHC GF L D+++CR I+YC+
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLC 323
C+HECV+ C C G+ L P+G++C D C DHGCE C++ S+ C C
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469
Query: 324 PEGRQLQADGKSCNRCREGHVDLVLLVD 351
EG + D K+C+R VD LL D
Sbjct: 470 SEGFLINEDLKTCSR-----VDYCLLSD 492
Score = 128 bits (322), Expect = 1e-29
Identities = 53/123 (43%), Positives = 74/123 (60%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTP 275
+D CA+ HGCE C+N+ S+ C C GF++ +D ++C +DYC +H C++ CV+
Sbjct: 444 VDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMD 503
Query: 276 GGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKS 335
C C EGH L+ DG++C D C DHGCE CVS S+ C C EG L+ DGK+
Sbjct: 504 RSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKT 563
Query: 336 CNR 338
C R
Sbjct: 564 CRR 566
Score = 37.0 bits (84), Expect = 0.050
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 535 ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQL 577
E C+CE+L+ FQ + LT L ++T R+E LEN+L
Sbjct: 911 EKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRL 953
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 311 bits (797), Expect = 1e-84
Identities = 148/313 (47%), Positives = 213/313 (68%), Gaps = 3/313 (0%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C + PLDLVF+IDSSRSVRP EF ++ F+ ++ L++GP TRV V+ Y+S V+ F
Sbjct: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L+A++ ++ +++A+ + PL+ GTM+GLAIQ AM+ AF+V GAR P +P+VA+IVTD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
Query: 208 QFQSRLCAIDLCAEGTHGCEHHCV-NSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHS 266
+FQ CA+D C GTH C+H C+ + G + C C G+ L D+++C A+D C+ H
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG 316
Query: 267 CQHECVSTPGGP-RCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL-SYRCLCP 324
C+H CV+ G C C EG+ L D ++C +D C HGC+ CV++ S+ C C
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQHICVNDRTGSHHCECY 376
Query: 325 EGRQLQADGKSCN 337
EG L AD K+C+
Sbjct: 377 EGYTLNADKKTCS 389
Score = 158 bits (400), Expect = 1e-38
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C+ +DLV ++D S+SVRP F VK FV++I+D LD+ P TRV +V ++S V+ EF
Sbjct: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L Y +KQAV + + GTM+GLA++ ++ +F+ GAR + N+P+V ++ TD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
GR QD ++ AARA+ GI +YAVGV +A A L+ +ASEP E HV Y +G + L
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
Query: 519 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 562
+ + C + GT E + CEC + +T AL+ LN
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
Score = 84.0 bits (206), Expect = 4e-16
Identities = 43/102 (42%), Positives = 56/102 (54%), Gaps = 7/102 (6%)
Query: 215 AIDLCAEGTHGCEHHCVNS-PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVS 273
A D CA GTHGC+H CVN GS+ C C G+ L D+++C D C+ G+H CQH CVS
Sbjct: 348 AQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
Query: 274 TPGGP-RCHCREGHDLQPDGRSC----QVRDLCNGVDH-GCE 309
C C G+ L D ++C + R L + D GCE
Sbjct: 408 DGAASYHCDCYPGYTLNEDKKTCSATEEARRLVSTEDACGCE 449
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 278 bits (710), Expect = 1e-74
Identities = 151/285 (52%), Positives = 191/285 (67%), Gaps = 16/285 (5%)
Query: 295 CQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGH----VDLVLLV 350
C V DLC DH CE C+S SY C C EG L +DGK+CN C G DLV L+
Sbjct: 221 CVVSDLCATGDHDCEQVCISSPGSYTCACHEGFTLNSDGKTCNVCSGGGGSSATDLVFLI 280
Query: 351 DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 410
DGSKSVRP+NFELVK+F++QIVD LDVS + +VGLVQ+SS VR EFPLGR+ T ++K
Sbjct: 281 DGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKA 340
Query: 411 AVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAA 470
AV + YME+GTMTG AL++++++SF+ + GARP A +VG+VFTDGRSQD I+ A
Sbjct: 341 AVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGA---QKVGIVFTDGRSQDYINDAAK 397
Query: 471 RAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGI 530
+AK+ G M+AVGVG AVE ELREIASEP H Y DF T+ + + L+ IC EE
Sbjct: 398 KAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKKICVEE-- 455
Query: 531 SAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLEN 575
PC CESLV+FQ + G L++LT L ++ RL LEN
Sbjct: 456 -------DPCACESLVKFQAKVEGLLQALTRKLEAVSKRLAILEN 493
Score = 243 bits (621), Expect = 3e-64
Identities = 142/322 (44%), Positives = 191/322 (59%), Gaps = 8/322 (2%)
Query: 10 LLLLLQPWETQ---LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNV 66
LLLLLQ + Q G C T P DLVFV+DSSRSVRP EFE ++ FL ++ L+V
Sbjct: 14 LLLLLQALCSPGLAPQSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDV 73
Query: 67 GPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFS 126
GPNATRVG++ Y+S V+ F LRA + + +A+R + PL+ GTMTGLAIQ+A+ AF
Sbjct: 74 GPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFG 133
Query: 127 VAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
AEG R + +V ++VTDGRPQD V +V+A+ARA G+E++A+GV D +LR +AS
Sbjct: 134 DAEGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVGSVDKATLRQIAS 193
Query: 187 PPLDEHVFLVESFDLIQEFGLQFQSRLCAI-DLCAEGTHGCEHHCVNSPGSYFCHCQVGF 245
P DEHV VES+ +I++ +FQ C + DLCA G H CE C++SPGSY C C GF
Sbjct: 194 EPQDEHVDYVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCEQVCISSPGSYTCACHEGF 253
Query: 246 VLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVD 305
L D ++C + CS G S + V G + E +L S Q+ D + D
Sbjct: 254 TLNSDGKTC---NVCSGGGGSSATDLVFLIDGSKSVRPENFELVKKFIS-QIVDTLDVSD 309
Query: 306 HGCEFQCVSEGLSYRCLCPEGR 327
+ V S R P GR
Sbjct: 310 KLAQVGLVQYSSSVRQEFPLGR 331
Score = 161 bits (408), Expect = 1e-39
Identities = 91/246 (36%), Positives = 139/246 (56%), Gaps = 5/246 (2%)
Query: 317 LSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD 376
L + LC G Q+ G + CR DLV +VD S+SVRP FE VK F++Q+++ LD
Sbjct: 16 LLLQALCSPGLAPQSRG---HLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLD 72
Query: 377 VSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSF 436
V P TRVG+V ++S V+ EF L + + A + QAV ++ + GTMTGLA++ + +F
Sbjct: 73 VGPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAF 132
Query: 437 SEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIA 496
+A+G R R+ ++ +V +V TDGR QD + +ARA+ G+ ++A+GVG +A LR+IA
Sbjct: 133 GDAEGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVGSVDKATLRQIA 192
Query: 497 SEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGAL 556
SEP + HV Y + + L + + C + A + CE + T
Sbjct: 193 SEPQDEHVDYVESYSVIEKLSRKFQEAFCVVSDLCATGD--HDCEQVCISSPGSYTCACH 250
Query: 557 ESLTLN 562
E TLN
Sbjct: 251 EGFTLN 256
Score = 144 bits (362), Expect = 3e-34
Identities = 74/188 (39%), Positives = 120/188 (63%), Gaps = 4/188 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
DLVF+ID S+SVRP FE +++F+ ++ L+V +VG++QYSS V+ FPL F
Sbjct: 275 DLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHT 334
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
++D++ A+R++ + +GTMTG A++Y ++ +F+V+ GARP + +V ++ TDGR QD
Sbjct: 335 KKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQ---KVGIVFTDGRSQDY 391
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
+ + A +A+ G +++AVGV A LR +AS P+ EH F F I + G + Q ++
Sbjct: 392 INDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKKI 451
Query: 214 CA-IDLCA 220
C D CA
Sbjct: 452 CVEEDPCA 459
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 213 bits (542), Expect = 4e-55
Identities = 157/516 (30%), Positives = 253/516 (49%), Gaps = 27/516 (5%)
Query: 15 QPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG 74
+P +T++Q T DLVF++D S SV F+ + F+ L+ ++G TRVG
Sbjct: 124 KPGKTEIQKCSVSAWT---DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180
Query: 75 VIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPP 134
V+QYSS ++ F L + +R+++ AI+ + TMTG AI Y + F+ + GAR
Sbjct: 181 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR-- 238
Query: 135 EERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVF 194
P+VA+I+TDG+ QD V A + R G+E++++G++ AD L+ +AS P HVF
Sbjct: 239 -VGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVF 297
Query: 195 LVESFDLIQEFGLQFQSRLCA--IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQR 252
V +FD I + + S++C+ + E G E V P S + +
Sbjct: 298 NVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEE---VVEPPS-------NLIAMEVSS 347
Query: 253 SCRAIDYCSFGNHSCQHECVSTP--GGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEF 310
+++ + ++ + TP G R H + P + VRDL ++
Sbjct: 348 KYVKLNWNPSPSPVTGYKVILTPMTAGSRQHAL---SVGPQTTTLSVRDLSADTEYQISV 404
Query: 311 QCVSEGLSYRCL-CPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVN 369
+ S + E Q C+R + D+V LVDGS S+ NF V+ F+
Sbjct: 405 SAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLE 464
Query: 370 QIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALR 429
+V ++SP ++ LVQ+S TEF L ++ ++ +A+ Y T TG A+
Sbjct: 465 VLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMT 524
Query: 430 HMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVE 489
++ E F ++G+R NVP+V ++ TDG+S D A + + + ++AVGV AV
Sbjct: 525 YVREKIFVPSKGSRS---NVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVR 581
Query: 490 AELREIASEPAELHVSYAPDFGTMTHLLENLRGSIC 525
+EL IAS PAE HV DF + L SIC
Sbjct: 582 SELEAIASPPAETHVFTVEDFDAFQRISFELTQSIC 617
Score = 131 bits (329), Expect = 2e-30
Identities = 64/181 (35%), Positives = 112/181 (61%), Gaps = 3/181 (1%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+VLLVDGS S+ NF V+ F+++IV+ D+ P+ ++ L Q+S RTE+ L +
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
+ QAV + Y T+TG+AL + + +F G RPRA ++G++ TDG+SQDD
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA---RKIGVLITDGKSQDD 1315
Query: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 524
+ + + K+EG+ ++A+G+ A E EL+ IA++P + H DF +++ ++++L ++
Sbjct: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375
Query: 525 C 525
C
Sbjct: 1376 C 1376
Score = 110 bits (274), Expect = 5e-24
Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 397
C+ D+V L D S S+ NF V +F+ N + F ++SP G +V VQ+S V++EF
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
Query: 398 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 457
L Y A A+ + Y T TG AL + E + G R NVP+V +V T
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 2433
Query: 458 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 517
DGRSQD++ A ++ G ++ VGV EL IAS+P+E HV DF + +
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 2493
Query: 518 ENLRGSIC 525
+NL +C
Sbjct: 2494 DNLITFVC 2501
Score = 99.0 bits (245), Expect = 1e-20
Identities = 52/192 (27%), Positives = 99/192 (51%), Gaps = 4/192 (2%)
Query: 24 TGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQV 82
+G C T D+V ++D S S+ F T+R F+ ++ ++GP ++ + QYS
Sbjct: 1188 SGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDP 1247
Query: 83 QSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVA 142
++ + L A ++ + +A+ +L T+TG+A+ + F G RP R ++
Sbjct: 1248 RTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---RARKIG 1304
Query: 143 VIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLI 202
V++TDG+ QD V + + + G+E++A+G++ AD L+ +A+ P D H + V F+ +
Sbjct: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364
Query: 203 QEFGLQFQSRLC 214
LC
Sbjct: 1365 SRIVDDLTINLC 1376
Score = 92.8 bits (229), Expect = 8e-19
Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C D+VF+ D+S S+ F + +F+ + G + + P +V +QYS +V+S F
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L ++ + A++++ T TG A+ + + G R + VP+V V+VT
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 2433
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
DGR QD V + A + G ++ VGV D L +AS P + HVF+V+ F+ ++
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 2491
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 168 bits (425), Expect = 1e-41
Identities = 148/509 (29%), Positives = 230/509 (45%), Gaps = 50/509 (9%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
+D++F++D S SV FE + F + + GL++ P RVG Q+SS FPL +FS
Sbjct: 50 VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+++++ I+ +V T T LA++Y ++ A VP++ +IVTDG+ Q
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--FGLQFQ 210
VA + Q + RG+ ++AVGV+ L A+AS P +HV L E + F
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224
Query: 211 SRLC--AIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAI--DYCSFGNHS 266
S +C A C H CEH + + + + R A+ +C F +S
Sbjct: 225 SAICSSATPDCRVEAHPCEHRTLEMVREFAGNAP----CWRGSRRTLAVLAAHCPF--YS 278
Query: 267 CQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL-SYRCLCP 324
+ ++ P R C D QP CQ NG CV EGL Y+CLCP
Sbjct: 279 WKRVFLTHPATCYRTTCPGPCDSQP----CQ-----NG------GTCVPEGLDGYQCLCP 323
Query: 325 --EGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGT 382
G + K CR VDL+ L+D S F K FV + V +
Sbjct: 324 LAFGGEANCALKLSLECR---VDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRA 380
Query: 383 RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA 442
RVG+ +S + P+G Y ++ ++ + + T+TG ALR E F A
Sbjct: 381 RVGVATYSRELLVAVPVGEYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRT 440
Query: 443 ---RPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
RPR RV ++ T+ S+D+++ A A+ +++ VG +AV AEL EI P
Sbjct: 441 GQDRPR-----RVVVLLTESHSEDEVAGPARHARARELLLLGVG-SEAVRAELEEITGSP 494
Query: 500 AELHVSYAPDFGTMTHLLENLRGSICPEE 528
HV D + + + L+G +C +
Sbjct: 495 K--HVMVYSDPQDLFNQIPELQGKLCSRQ 521
Score = 112 bits (279), Expect = 1e-24
Identities = 77/212 (36%), Positives = 109/212 (51%), Gaps = 11/212 (5%)
Query: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 403
VD++ L+DGS SV +FE K F + D LD+SPE RVG QFSS EFPL +
Sbjct: 50 VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109
Query: 404 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
T EVK + + + T T LAL++++ + A +VP++ ++ TDG+SQ
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH-LLENLRG 522
D+++ + + KE G+ ++AVGV EL +ASEP HV A T+ L L
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224
Query: 523 S-ICPEEGISAGTELRSPCE---CESLVEFQG 550
S IC E PCE E + EF G
Sbjct: 225 SAICSSATPDCRVEAH-PCEHRTLEMVREFAG 255
Score = 98.2 bits (243), Expect = 2e-20
Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 8/185 (4%)
Query: 330 QADGKSCNR----CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVG 385
+ GK C+R CR +DLV ++D S SV P+NF ++ FV +V+P+ T+VG
Sbjct: 512 ELQGKLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVG 571
Query: 386 LVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 445
LV + S+V+T F L T A + +A+ Y+ G AL H+ + + +GARP
Sbjct: 572 LVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP- 630
Query: 446 ALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIAS-EPAELHV 504
VP+ +V T GR +D +V A + + GI + VGVG + LR +A + +HV
Sbjct: 631 --GVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHV 688
Query: 505 SYAPD 509
+ D
Sbjct: 689 AAYAD 693
Score = 92.4 bits (228), Expect = 1e-18
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P C T LDLVF++D+S SV P F M+ F+ V P+ T+VG++ Y SQVQ+
Sbjct: 523 PGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTA 582
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIV 145
F L R M RAI L G A+ + + +V GARP VP+ V++
Sbjct: 583 FGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP---GVPKAVVVL 639
Query: 146 TDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASP 187
T GR + A A + R GI + VGV LR +A P
Sbjct: 640 TGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGP 681
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 149 bits (376), Expect = 7e-36
Identities = 82/187 (43%), Positives = 113/187 (60%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C+ H DLV L+D S SV ++FE V+++V +VD +V P+ TRVG+V++S R T F
Sbjct: 32 CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFE 91
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
LG +G+ EVK A + Y T TG ALR++ SFS G RPR +V ++ TD
Sbjct: 92 LGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTD 151
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
GRSQD + AA A GI ++AVGVG+A++ EL EIASEP HV + DF + +
Sbjct: 152 GRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRG 211
Query: 519 NLRGSIC 525
LR +C
Sbjct: 212 KLRRRLC 218
Score = 132 bits (332), Expect = 9e-31
Identities = 83/214 (38%), Positives = 117/214 (54%), Gaps = 6/214 (2%)
Query: 10 LLLLLQPWE----TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN 65
LL +L W Q Q G C + DLVF++D+S SV +FE +RQ++ L+
Sbjct: 12 LLWMLLLWSGGGGCQAQRAG--CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFE 69
Query: 66 VGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAF 125
VGP+ TRVGV++YS + + F L F +E+++ A R L T TG A++Y +F
Sbjct: 70 VGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSF 129
Query: 126 SVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
S G RP + +VA+++TDGR QD V + AA A GI I+AVGV A L +A
Sbjct: 130 SPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIA 189
Query: 186 SPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLC 219
S P HVF V F+ I + + + RLC LC
Sbjct: 190 SEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLC 223
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 134 bits (338), Expect = 2e-31
Identities = 67/197 (34%), Positives = 118/197 (59%), Gaps = 5/197 (2%)
Query: 329 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 388
++A+G C D+VLLVDGS S+ NF V+ F+++IV+ D+ P+ ++ L Q
Sbjct: 21 IEAEGMEC--LTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78
Query: 389 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 448
+S RTE+ L + + QAV + Y T+TG+AL + + +F G RPRA
Sbjct: 79 YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA-- 136
Query: 449 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAP 508
++G++ TDG+SQDD+ + + K+EG+ ++A+G+ A E EL+ IA++P + H
Sbjct: 137 -RKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195
Query: 509 DFGTMTHLLENLRGSIC 525
DF +++ ++++L ++C
Sbjct: 196 DFESLSRIVDDLTINLC 212
Score = 110 bits (274), Expect = 5e-24
Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 397
C+ D+V L D S S+ NF V +F+ N + F ++SP G +V VQ+S V++EF
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212
Query: 398 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 457
L Y A A+ + Y T TG AL + E + G R NVP+V +V T
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 1269
Query: 458 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 517
DGRSQD++ A ++ G ++ VGV EL IAS+P+E HV DF + +
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 1329
Query: 518 ENLRGSIC 525
+NL +C
Sbjct: 1330 DNLITFVC 1337
Score = 99.8 bits (247), Expect = 6e-21
Identities = 52/197 (26%), Positives = 101/197 (51%), Gaps = 4/197 (2%)
Query: 19 TQLQLTGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQ 77
+ ++ G C T D+V ++D S S+ F T+R F+ ++ ++GP ++ + Q
Sbjct: 19 SSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78
Query: 78 YSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEER 137
YS ++ + L A ++ + +A+ +L T+TG+A+ + F G RP R
Sbjct: 79 YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---R 135
Query: 138 VPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVE 197
++ V++TDG+ QD V + + + G+E++A+G++ AD L+ +A+ P D H + V
Sbjct: 136 ARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195
Query: 198 SFDLIQEFGLQFQSRLC 214
F+ + LC
Sbjct: 196 DFESLSRIVDDLTINLC 212
Score = 92.8 bits (229), Expect = 8e-19
Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C D+VF+ D+S S+ F + +F+ + G + + P +V +QYS +V+S F
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L ++ + A++++ T TG A+ + + G R + VP+V V+VT
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 1269
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
DGR QD V + A + G ++ VGV D L +AS P + HVF+V+ F+ ++
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 1327
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 134 bits (336), Expect = 3e-31
Identities = 74/181 (40%), Positives = 109/181 (60%), Gaps = 3/181 (1%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V+LVDGS S+ NF LV+ F+ +V DV E TR+GL Q+S R E+ L + T
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
EV +AV + Y T+TGLAL ++ E+SF G+R V ++G++ TDG+SQDD
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILITDGKSQDD 274
Query: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 524
I + +E G+ ++A+GV A EL+EIASEP HV +F M ++E+L ++
Sbjct: 275 IIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTL 334
Query: 525 C 525
C
Sbjct: 335 C 335
Score = 118 bits (296), Expect = 1e-26
Identities = 64/189 (33%), Positives = 104/189 (55%), Gaps = 4/189 (2%)
Query: 28 CHTGPL-DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
C T + D+V ++D S S+ F F +R FL L+ +VG TR+G+ QYS + +
Sbjct: 151 CQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEW 210
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L AFS ++++ A+R+L T+TGLA+ Y +F G+R V ++ +++T
Sbjct: 211 HLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILIT 267
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DG+ QD + + R G+E++A+GV+ ADV L+ +AS P HV+ V FDL+
Sbjct: 268 DGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVV 327
Query: 207 LQFQSRLCA 215
LC+
Sbjct: 328 ESLTRTLCS 336
Score = 111 bits (277), Expect = 2e-24
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 4/188 (2%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 397
C+ DLV +VDGS S+ +NF + F+ V L+ + +GT+V +VQF+ RTEF
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085
Query: 398 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 457
L Y T + A+ + Y T TG A++++ + F+ G R +P+V +V T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRR---GIPKVIVVIT 1142
Query: 458 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 517
DGRSQDD++ + + +G ++A+GV A +EL I S+P+ HV + DF +
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202
Query: 518 ENLRGSIC 525
+ L +C
Sbjct: 1203 DELITFVC 1210
Score = 107 bits (267), Expect = 3e-23
Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 4/188 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C DLVF++D S S+ F + FL + LN +G + T+V ++Q++ ++ F
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L A+ +E + AI+ + T TG AI+Y + F+ G R +P+V V++T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTR---RGIPKVIVVIT 1142
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V +++ + + G I+A+GV AD L ++ S P HVF V+ FD ++
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 1203 DELITFVC 1210
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 129 bits (323), Expect = 1e-29
Identities = 69/200 (34%), Positives = 119/200 (59%), Gaps = 7/200 (3%)
Query: 329 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 388
L DG+ + CR DLV ++DGS SV P+NFE+VK+++ I D+ P+ +VG+VQ
Sbjct: 21 LAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQ 80
Query: 389 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 448
+S E PLG Y + + AV ++ Y+ T TG A++ +++ F+++ +
Sbjct: 81 YSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKS------SRF 134
Query: 449 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAELHVSYA 507
+ ++ +V TDG+SQDD+ A A++ I ++A+GVG E AELR IA++P+ +V Y
Sbjct: 135 LTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYV 194
Query: 508 PDFGTMTHLLENLRGSICPE 527
D+ ++ + E ++ +C E
Sbjct: 195 EDYIAISKIREVMKQKLCEE 214
Score = 120 bits (300), Expect = 4e-27
Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 7/216 (3%)
Query: 5 LCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
LC ++LLL + C T P DLVF++D S SV P FE ++++L+ + +
Sbjct: 8 LCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNF 67
Query: 65 NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVA 124
++GP +VGV+QYS PL ++ E + A+ ++ L T TG AIQ+A++
Sbjct: 68 DIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYL 127
Query: 125 FSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGV-QRADVGSLRA 183
F+ + + ++AV++TDG+ QD V + A AR I ++A+GV + LRA
Sbjct: 128 FAKS------SRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRA 181
Query: 184 MASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLC 219
+A+ P +VF VE + I + + +LC +C
Sbjct: 182 IANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVC 217
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 121 bits (303), Expect = 2e-27
Identities = 64/132 (48%), Positives = 75/132 (56%), Gaps = 5/132 (3%)
Query: 209 FQSRLCAIDLCAEGTH--GCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHS 266
FQ C D+ TH GC+H CVN+PGSY C C+ GF L D R+C AI+ C+ GN
Sbjct: 153 FQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG 212
Query: 267 CQHECVS-TPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQC-VSEGLSYRCLCP 324
CQH CV T RC CR G LQ DGR C R C + C +C V GL+ RC C
Sbjct: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLA-RCECH 271
Query: 325 EGRQLQADGKSC 336
G QL ADGK+C
Sbjct: 272 VGYQLAADGKAC 283
Score = 105 bits (261), Expect = 1e-22
Identities = 54/136 (39%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
Query: 205 FGLQFQSRLC-AIDLCAEGTHGCEHHCVN-SPGSYFCHCQVGFVLQQDQRSCRAIDYCSF 262
F L SR C AI+ CA G GC+HHCV + + C C+ GF LQ+D R C C+
Sbjct: 191 FRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCAN 250
Query: 263 GNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCL 322
N SC H C G RC C G+ L DG++C+ D C C C++ S++C+
Sbjct: 251 RNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCV 310
Query: 323 CPEGRQLQADGKSCNR 338
C G +L ADG+ C R
Sbjct: 311 CHAGYELGADGRQCYR 326
Score = 95.1 bits (235), Expect = 2e-19
Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTP 275
++ C GC H C ++ C C G+ L DQR+C +D C+ + CQ C + P
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQVCTNNP 390
Query: 276 GGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKS 335
GG C C G+ L DG C+ D C GCE C + S++C C G +L D +
Sbjct: 391 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRG 450
Query: 336 CNRCREGHVDL 346
C+ E VDL
Sbjct: 451 CSPLEEPMVDL 461
Score = 89.0 bits (219), Expect = 1e-17
Identities = 46/126 (36%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY-----CSFGNHSCQHE 270
+D CA G C H C+N+ GS+ C C G+ L D R C I+ C N C H
Sbjct: 286 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG 345
Query: 271 CVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQ 330
C T GP C C G++L D R+C D C C+ C + Y C C G +L
Sbjct: 346 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC-ADSPCCQQVCTNNPGGYECGCYAGYRLS 404
Query: 331 ADGKSC 336
ADG C
Sbjct: 405 ADGCGC 410
Score = 68.6 bits (166), Expect = 2e-11
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
+ L R C +D CA+ C+ C N+PG Y C C G+ L D C +D C+
Sbjct: 361 YELDTDQRTCIDVDDCADSPC-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSC 295
C+H C + G +C C G+ L D R C
Sbjct: 420 RGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 44.3 bits (103), Expect = 3e-04
Identities = 43/158 (27%), Positives = 56/158 (35%), Gaps = 34/158 (21%)
Query: 206 GLQFQSRLCAIDLCAEGTHG--------CEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAI 257
GL + R C + C G +G C ++ P + C C GF Q + C
Sbjct: 1323 GLGWTGRHCEL-ACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP- 1380
Query: 258 DYCSFGNHSCQHECVSTPGGP------RCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQ 311
F CQ C G P RC C G R C+ GC +
Sbjct: 1381 ---GFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP----GSFGEGCHQR 1433
Query: 312 CVSEG------LSYRCLCPEGRQLQADGKSCN-RCREG 342
C +G ++ CLCP GR G +CN CR G
Sbjct: 1434 CDCDGGAPCDPVTGLCLCPPGR----SGATCNLDCRRG 1467
Score = 43.5 bits (101), Expect = 5e-04
Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 20/118 (16%)
Query: 224 HGCEHHCVNSPGSYF------CHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGG 277
H C C G+ CHC G++ ++C A Y +C+H C+ GG
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY----GDNCRHSCLCQNGG 1052
Query: 278 PRCHCREGHDLQPD---GRSCQVRDLCNGVDHGCEFQ--CVSEGL----SYRCLCPEG 326
C GH P+ G +C+ L V GC C++ GL + RCLCP G
Sbjct: 1053 -TCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAG 1109
Score = 37.7 bits (86), Expect = 0.029
Identities = 37/137 (27%), Positives = 46/137 (33%), Gaps = 22/137 (16%)
Query: 219 CAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY-------CSFGN----HSC 267
C E C+H P + C C GFV + Q C A Y CS N H
Sbjct: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPA 841
Query: 268 QHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGR 327
C PG C+ D G C C+ C + +S CLC G
Sbjct: 842 TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC------DAISGLCLCEAGY 895
Query: 328 QLQADGKSC-NRCREGH 343
G C +C +GH
Sbjct: 896 V----GPRCEQQCPQGH 908
Score = 37.0 bits (84), Expect = 0.050
Identities = 36/133 (27%), Positives = 43/133 (32%), Gaps = 18/133 (13%)
Query: 219 CAEGTHG--CEHHCVNSPGSY------FCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHE 270
CA G HG C+ C PG Y C C G +CR F C
Sbjct: 1193 CAAGYHGPSCQQRC--PPGRYGPGCEQLCGCLNGGSCDAATGACRCPT--GFLGTDCNLT 1248
Query: 271 CVSTPGGPRCH----CREGHDLQPDGRSCQVRDLCNGV--DHGCEFQCVSEGLSYRCLCP 324
C GP C C +G P +C GV + GC G + C C
Sbjct: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
Query: 325 EGRQLQADGKSCN 337
G A SC+
Sbjct: 1309 NGGLCHASNGSCS 1321
Score = 36.6 bits (83), Expect = 0.065
Identities = 39/151 (25%), Positives = 49/151 (32%), Gaps = 41/151 (27%)
Query: 219 CAEGTHG--CEHHCVNSPGSYF-------CHCQVGFVLQQDQRSC---------RAIDYC 260
C G G CEH C P +F C+C G SC R + C
Sbjct: 934 CPAGWRGTFCEHAC---PAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETC 990
Query: 261 ---SFGNHSCQHECVSTPGGP------RCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQ 311
++G H+C C G +CHC G G SC C
Sbjct: 991 PAHTYG-HNCSQACACFNGASCDPVHGQCHCAPGWM----GPSCLQACPAGLYGDNCRHS 1045
Query: 312 CVSEG------LSYRCLCPEGRQLQADGKSC 336
C+ + +S C CPEG A K C
Sbjct: 1046 CLCQNGGTCDPVSGHCACPEGWAGLACEKEC 1076
Score = 35.0 bits (79), Expect = 0.19
Identities = 48/187 (25%), Positives = 64/187 (34%), Gaps = 64/187 (34%)
Query: 217 DLCAEGTHG--CEHHCVNS------PGSYFCHCQVGFVLQQDQRSCRAIDY--------- 259
D+C G +G C+ C + P + C C G+ QR+C +
Sbjct: 815 DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 874
Query: 260 CSFGNHSCQHE---CVSTPG--GPRCH--CREGHDLQPDGRSCQVRDLCN---GVDHG-- 307
CS G+ SC C+ G GPRC C +GH G C+ R C DH
Sbjct: 875 CSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHF----GPGCEQRCQCQHGAACDHVSG 930
Query: 308 ------------CEFQCVSE--GLSYR-----------------CLCPEGRQLQADGKSC 336
CE C + GL R CLCP GR+ ++C
Sbjct: 931 ACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETC 990
Query: 337 NRCREGH 343
GH
Sbjct: 991 PAHTYGH 997
Score = 31.6 bits (70), Expect = 2.1
Identities = 39/162 (24%), Positives = 50/162 (30%), Gaps = 37/162 (22%)
Query: 212 RLCAIDLCAEGTHGCEHHCVNSPGSYF------CHCQVGFVLQQDQRSCRAIDYCSFGNH 265
RL LC G +G H P ++ C C D+R F
Sbjct: 621 RLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
Query: 266 SCQHECVSTPGGPRC---------------------HCREGHDLQPDGRSCQVRDLCNGV 304
CQ EC GP C C G + G+ C V GV
Sbjct: 681 RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF--GV 738
Query: 305 DHGCEFQC---VSEGLSYRCLCPEGRQLQADGKSCNR-CREG 342
+ C G++ +C CP GR G+ C C EG
Sbjct: 739 NCSSSCSCGGAPCHGVTGQCRCPPGR----TGEDCEADCPEG 776
Score = 30.8 bits (68), Expect = 3.6
Identities = 35/144 (24%), Positives = 46/144 (31%), Gaps = 28/144 (19%)
Query: 225 GCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAID---YCSFGNH--SCQHECVSTPGGPR 279
GCE C PGS+ C + +C C+ G H SCQ C GP
Sbjct: 1157 GCEQAC--PPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPG 1214
Query: 280 CH----CREGHDLQPDGRSCQVRDLCNGVDH-----------------GCEFQCVSEGLS 318
C C G +C+ G D GC + ++
Sbjct: 1215 CEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVT 1274
Query: 319 YRCLCPEGRQLQADGKSCNRCREG 342
CLCP GR + C + R G
Sbjct: 1275 GTCLCPPGRAGVRCERGCPQNRFG 1298
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 118 bits (295), Expect = 2e-26
Identities = 76/223 (34%), Positives = 117/223 (52%), Gaps = 5/223 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V LVDGS S+ +F+ VK F+ ++ ++ P+ +VGL Q+S +TE+ L T
Sbjct: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
+V AV + Y T TGLAL H++ + A G RP A +V ++ TDG+SQDD
Sbjct: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEA---AKVVILVTDGKSQDD 295
Query: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 524
+ A K+ G+ ++AVGV A EAELR +AS P ++ V DF + L L I
Sbjct: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355
Query: 525 CPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLT 567
C + + G+ + P +L T L +T + +L+
Sbjct: 356 C--QRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLS 396
Score = 107 bits (268), Expect = 2e-23
Identities = 59/168 (35%), Positives = 91/168 (54%), Gaps = 3/168 (1%)
Query: 32 PLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAF 91
P D+VF++D S S+ F+ ++ FL ++ +GP+ +VG+ QYS Q+ + L +
Sbjct: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S +E + A+R L T TGLA+ + + A G RP +V ++VTDG+ Q
Sbjct: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP---EAAKVVILVTDGKSQ 293
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V A + G+ ++AVGV+ AD LR +ASPP D V V F
Sbjct: 294 DDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDF 341
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 110 bits (276), Expect = 3e-24
Identities = 61/201 (30%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
Query: 327 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 386
R D +C++ D+ ++DGS SV NF V +FV + ++S TR+G
Sbjct: 492 RVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGA 551
Query: 387 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 446
VQ++ R EF +Y + ++ A+ V Y GT TG A+ +E F +++
Sbjct: 552 VQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP----- 606
Query: 447 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 506
N ++ ++ TDGRS DD+ + A A +G++ YA+GV A + EL IA+ PA H +
Sbjct: 607 -NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFF 665
Query: 507 APDFGTMTHLLENLRGSICPE 527
+F + + + +IC E
Sbjct: 666 VDEFDNLHQYVPRIIQNICTE 686
Score = 94.7 bits (234), Expect = 2e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ FVID S SV F T+ QF+ L + + TR+G +QY+ + + F +S
Sbjct: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ D+ AI+ + + GT TG AI +A+ F ++ P +R ++ +++TDGR D
Sbjct: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSK----PNKR--KLMILITDGRSYDD 623
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
V A A +G+ YA+GV A L +A+ P +H F V+ FD + ++ + +
Sbjct: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
Query: 214 C 214
C
Sbjct: 684 C 684
Score = 82.0 bits (201), Expect = 1e-15
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 17/231 (7%)
Query: 21 LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
+ L P C +DL F+ID S S+ F +Q L + + L++GP +GV+QY
Sbjct: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354
Query: 81 QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
+ F L+ + D++ AI + + G AI + FS A G R P
Sbjct: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411
Query: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFL----V 196
V V++ DG P D+V E + AR GI I+ + ++ A + + P
Sbjct: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGF 471
Query: 197 ESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVL 247
S + FGL + +C C C+NS +GFV+
Sbjct: 472 YSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNS-------ADIGFVI 515
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 403
+DL L+DGS S+ + F + K+ + + LD+ P G +G+VQ+ T F L +
Sbjct: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
Query: 404 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
+ ++K A+ + + G A+ + ++ FS+A G R A P V +V DG D
Sbjct: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGA---PNVVVVMVDGWPTD 423
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
+ + A+E GI ++ + + A E E ++ EP
Sbjct: 424 KVEEASRLARESGINIFFITIEGAAENE-KQYVVEP 458
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 109 bits (273), Expect = 6e-24
Identities = 62/180 (34%), Positives = 99/180 (55%), Gaps = 6/180 (3%)
Query: 24 TGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQ 83
T C D++F++DSS S+ P F M+ F+ L+ +GP+ ++GV+Q+S +
Sbjct: 612 TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINK 671
Query: 84 SVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L F + D+ AI + + Q T+TG A+ + FS +GARP + + +
Sbjct: 672 EEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQY-FSPTKGARP---NIRKFLI 727
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
++TDG QD V E A R G+ IY+VGV ++V L ++ P E VF VE+FD++Q
Sbjct: 728 LITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMVFYVENFDILQ 785
Score = 107 bits (266), Expect = 4e-23
Identities = 60/187 (32%), Positives = 106/187 (56%), Gaps = 6/187 (3%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C+E D++ LVD S S+ P+NF +K F+ +V + P+ ++G+VQFS + EF
Sbjct: 616 CKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQ 675
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L R+ + +++ A+ + ++ + T+TG AL V FS +GARP N+ + ++ TD
Sbjct: 676 LNRFMSQSDISNAIDQMAHIGQTTLTGSAL-SFVSQYFSPTKGARP---NIRKFLILITD 731
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 518
G +QD + A ++EG+++Y+VGV + +L EI+ P V Y +F + + +
Sbjct: 732 GEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPE--MVFYVENFDILQRIED 789
Query: 519 NLRGSIC 525
+L IC
Sbjct: 790 DLVFGIC 796
Score = 101 bits (251), Expect = 2e-21
Identities = 59/157 (37%), Positives = 87/157 (55%), Gaps = 2/157 (1%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C VDLV L+DGS S++P +F+ +K F+ +V DVS R+G QFS EFP
Sbjct: 994 CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
LG + E+ + ++ + T G ALR VEH F G+R P+V LV TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALRE-VEHYFRPDMGSRINT-GTPQVLLVLTD 1111
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREI 495
G+SQD+++ A + GI +Y+VG+G + +L +I
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQI 1148
Score = 97.8 bits (242), Expect = 2e-20
Identities = 63/185 (34%), Positives = 99/185 (53%), Gaps = 7/185 (3%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+ LL+DGS S + +F +K F++++V +++P RVG VQ++ EF + +Y
Sbjct: 436 DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA-RPRALNVPRVGLVFTDGRSQD 463
++ +A+ + M T TG AL + S Q A + R VP +V T+G S+D
Sbjct: 496 KQDLGKAIENIRQMGGNTNTGAAL----NFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKD 551
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 523
I A R +EE I +YA+G+ +A + +LREIA E E V Y DF + + +
Sbjct: 552 SILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQVVQE 609
Query: 524 ICPEE 528
IC EE
Sbjct: 610 ICTEE 614
Score = 96.7 bits (239), Expect = 5e-20
Identities = 51/192 (26%), Positives = 100/192 (52%), Gaps = 5/192 (2%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
T D+ +ID S S + +F M+ FL ++ N+ P+ RVG +QY+ F +
Sbjct: 432 TEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEIN 491
Query: 90 AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
+S ++D+ +AI ++ + T TG A+ + +++ + + + +VP V++T+G
Sbjct: 492 KYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSL---LQKAKKQRGNKVPCHLVVLTNGM 548
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
+D + E A + R I +YA+G++ A+ LR +A ++ V+ V FD +++ Q
Sbjct: 549 SKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQV 606
Query: 210 QSRLCAIDLCAE 221
+C + C E
Sbjct: 607 VQEICTEEACKE 618
Score = 91.7 bits (226), Expect = 2e-18
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 4/187 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C +DLVF++D S S++P +F+ M++FL +++ +V N R+G Q+S FP
Sbjct: 994 CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L F +++ I ++ + T G A++ + F G+R P+V +++TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHY-FRPDMGSR-INTGTPQVLLVLTD 1111
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
G+ QD VA+ A R RGI+IY+VG+ DV + + E V +FD +++
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGI--GDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169
Query: 208 QFQSRLC 214
+ +C
Sbjct: 1170 RIVRNIC 1176
Score = 82.8 bits (203), Expect = 8e-16
Identities = 53/205 (25%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S + F+ ++ FL + L++ N RVG++ YS++ + + L
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ ++ + I++L P TG AI+ FS G+R + VP++AV+VT +D
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDN 347
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
V + A R G+ I+ +G++ A L +AS P +++V +++F + F +L
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
Query: 214 -----CAIDLCAEGTHGCEHHCVNS 233
+ + +E T + CV++
Sbjct: 408 RNQITHTVSVFSERTETLKSGCVDT 432
Score = 82.8 bits (203), Expect = 8e-16
Identities = 54/169 (31%), Positives = 95/169 (56%), Gaps = 6/169 (3%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LD+VFVIDSS S+ E+ M+ F++GL++ +VG N R G ++Y+ + +F L F
Sbjct: 808 LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFG 867
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ- 151
+ ++ +++ + T T A+ ++ ++ F+ A G+R + VP+V +++TDG
Sbjct: 868 TKLEVISVLQNDQAMGGSTYTAEALGFSDHM-FTEARGSR-LNKGVPQVLIVITDGESHD 925
Query: 152 -DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D++ A R +GI + AVG+ A+ L AMA + F VE+F
Sbjct: 926 ADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGS--SDKYFFVETF 972
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/202 (29%), Positives = 102/202 (50%), Gaps = 7/202 (3%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V L+D S + +NF+ +K F+ + V LD+ RVGLV +S+ + L
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
+EV Q + + TG A++ + + FS G+R + VP++ ++ T S+D+
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDN 347
Query: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMT----HLLENL 520
++ A + EG+ ++ +G+ A + +L +IAS PAE +VS F + L+ L
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
Query: 521 RGSICPEEGI-SAGTE-LRSPC 540
R I + S TE L+S C
Sbjct: 408 RNQITHTVSVFSERTETLKSGC 429
Score = 73.6 bits (179), Expect = 5e-13
Identities = 46/154 (29%), Positives = 79/154 (51%), Gaps = 2/154 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++DSS + F ++ F+ ++ L + + RV + QYS ++ S F L F
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 94 REDMERAIRDLVPLAQGTM-TGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
R M +R G++ G A+Q A FS R +++ P + V++ +D
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGR-DKKQFPPILVVLASSESED 145
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
V E + R G++I +VGVQ+A +L+AMA+
Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179
Score = 72.4 bits (176), Expect = 1e-12
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 6/184 (3%)
Query: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 403
+D+V ++D S S+ + ++K F+ +V DV R G ++++ F L +G
Sbjct: 808 LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFG 867
Query: 404 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
T EV + + M T T AL +H F+EA+G+R VP+V +V TDG S D
Sbjct: 868 TKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNK-GVPQVLIVITDGESHD 925
Query: 464 --DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 521
++ A +++GI++ AVG+ A EL +A + + FG + + ++
Sbjct: 926 ADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYF--FVETFGGLKGIFSDVT 983
Query: 522 GSIC 525
S+C
Sbjct: 984 ASVC 987
Score = 65.9 bits (159), Expect = 1e-10
Identities = 43/183 (23%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Query: 343 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 402
+ D+V LVD S + ++F VK F+ +++ L + + RV L Q+S ++ +EF L +
Sbjct: 25 YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTF 84
Query: 403 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 461
G + + ++ G AL+ FS R + P + +V S
Sbjct: 85 KGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKK-QFPPILVVLASSES 143
Query: 462 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG----TMTHLL 517
+D++ + +++G+ + +VGV KA E L+ +A+ ++ D MTH++
Sbjct: 144 EDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHII 203
Query: 518 ENL 520
+++
Sbjct: 204 KDV 206
Score = 49.7 bits (117), Expect = 7e-06
Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 12/164 (7%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG----VIQYSSQ 81
P C P +LVF +D SR V EFE M++ + L+R + V N+ VG ++ Y+S
Sbjct: 1749 PECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSH 1808
Query: 82 VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT---GLAIQYAMNVAFSVAEGARPPEERV 138
+ + ++ + R I + +P + + + G A+++ F P
Sbjct: 1809 ARHLVRFSDAYKKSQLLREI-ETIPYERSSASREIGRAMRFISRNVFK----RTLPGAHT 1863
Query: 139 PRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLR 182
++A + G+ D + A +EI V + ++V S+R
Sbjct: 1864 RKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVR 1907
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 31/196 (15%)
Query: 335 SCNRCR----EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRV 384
SC++ R + ++D L+D S+++ FE ++ F+ ++D +++PE G RV
Sbjct: 1951 SCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRV 2010
Query: 385 GLVQFS----------SRVRTEFPLGRYGTAAEVKQAV-LAVEYMERGTMTGLALRHMVE 433
L+ + S VR EF L Y + +K+ V +V+ + G AL+ ++
Sbjct: 2011 ALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLD 2070
Query: 434 HSFSEAQGARPRALNVPRVGLVFTDGRSQ----DDISVWAARAKEEGIVMYAVGVGKA-V 488
+ F R +V V + G + + + + RAK +G ++ +G
Sbjct: 2071 NVFLSTPNLRRN-----KVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWD 2125
Query: 489 EAELREIASEPAELHV 504
+ EL ++AS P + H+
Sbjct: 2126 DKELEDLASHPLDHHL 2141
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/183 (23%), Positives = 80/183 (43%), Gaps = 27/183 (14%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGP------NATRVGVIQYS------- 79
+D F++D+SR++ EFE +R FL LL + P RV ++ ++
Sbjct: 1964 MDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPN 2023
Query: 80 ---SQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVAEGARPPE 135
S V++ F L + + M+R + + V G G A+Q+ ++ F P
Sbjct: 2024 TQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVF-----LSTPN 2078
Query: 136 ERVPRVAVIVTDGRPQDRVAEV----AAQARARGIEIYAVGVQRA-DVGSLRAMASPPLD 190
R +V +++ G E+ + +A+ +G ++ + D L +AS PLD
Sbjct: 2079 LRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138
Query: 191 EHV 193
H+
Sbjct: 2139 HHL 2141
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 108 bits (270), Expect = 1e-23
Identities = 64/202 (31%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 328 QLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLV 387
Q D C +E D+ L+DGS S++ + FE +KRF+ ++ + + P+ RVG+V
Sbjct: 427 QRNLDKTGCVDTKEA--DIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVV 484
Query: 388 QFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRAL 447
Q+S EF + Y ++++A+ ++ + GT TG AL ++++ G + R
Sbjct: 485 QYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQ---IIKNGMKDRMS 541
Query: 448 NVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYA 507
VP +V TDG S D + A R + E I ++AVG+G A + EL+EIA + E VS+
Sbjct: 542 KVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGK--EERVSFG 599
Query: 508 PDFGTMTHLLENLRGSICPEEG 529
+F + + + IC E+G
Sbjct: 600 QNFDALKSIKNEVVREICAEKG 621
Score = 103 bits (257), Expect = 4e-22
Identities = 58/192 (30%), Positives = 104/192 (54%), Gaps = 5/192 (2%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
T D+ F+ID S S++ +FE +++F++ + ++GP+ RVGV+QYS + F +
Sbjct: 438 TKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYIT 497
Query: 90 AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
+S D+ +AI ++ L GT TG A+ Y + + + G + +VP +++TDG
Sbjct: 498 DYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQI---IKNGMKDRMSKVPCYLIVLTDGM 554
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
DRV E A + RA I ++AVG+ A+ L+ +A +E V ++FD ++ +
Sbjct: 555 STDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGK--EERVSFGQNFDALKSIKNEV 612
Query: 210 QSRLCAIDLCAE 221
+CA C +
Sbjct: 613 VREICAEKGCED 624
Score = 93.6 bits (231), Expect = 4e-19
Identities = 51/160 (31%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C + D++ LVD S S+ +NF +K F+ ++ + + + T++G+VQFS + + EF
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L RY T E+ A+ + + GT+TG AL + V F+ ++GAR L + ++ TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKAL-NFVGQYFTHSKGAR---LGAKKFLILITD 737
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASE 498
G +QDD+ A + + + +++VGV A ++L EI+ +
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD 777
Score = 92.0 bits (227), Expect = 1e-18
Identities = 55/192 (28%), Positives = 105/192 (54%), Gaps = 6/192 (3%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C D++F++DSS S+ F M+ F+ LL + +G + T++GV+Q+S + + F
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L + ++++ AI + + +GT+TG A+ + + F+ ++GAR + + +++TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VGQYFTHSKGARLGAK---KFLILITD 737
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
G QD V + A R + + I++VGV A+ L ++ VF VE+FD ++
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD--SSLVFHVENFDHLKALER 795
Query: 208 QFQSRLCAIDLC 219
+ R+CA+ C
Sbjct: 796 KLIFRVCALHDC 807
Score = 80.1 bits (196), Expect = 5e-15
Identities = 53/184 (28%), Positives = 97/184 (52%), Gaps = 6/184 (3%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LD+VFV+D S S++ + M + L++ +VG + + G ++YS Q +F L +S
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG--RP 150
R + +R T T A+++A N F+ G+R ++ V ++ +++TDG
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSR-IKQNVKQMLIVITDGESHD 930
Query: 151 QDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ 210
D++ + A + R +GI I+AVGV +A+ L MA + V++FD +++ Q
Sbjct: 931 HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988
Query: 211 SRLC 214
R+C
Sbjct: 989 ERMC 992
Score = 76.3 bits (186), Expect = 7e-14
Identities = 60/246 (24%), Positives = 112/246 (45%), Gaps = 16/246 (6%)
Query: 343 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 402
+ D+V LVD S + P++F VK F+N++++ L + RV L Q+S +EF L +
Sbjct: 28 YADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTF 87
Query: 403 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 461
G + + +++ G AL+ FS R R P + +V S
Sbjct: 88 KGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRK-QFPPILVVLASAES 146
Query: 462 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGT----MTHLL 517
+D++ + +++G+ + +VGV KA E L+ +A+ ++ D T MT ++
Sbjct: 147 EDEVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQII 206
Query: 518 ENLRGSICPEEGISAGTELRSPCECES--------LVEFQGRTLGALESLTLNLAQLTAR 569
+++ + E + A ++ P C+ LV+ T G L L L +T+
Sbjct: 207 KDV--TKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSS 264
Query: 570 LEDLEN 575
++ EN
Sbjct: 265 MDVKEN 270
Score = 75.9 bits (185), Expect = 1e-13
Identities = 54/183 (29%), Positives = 91/183 (49%), Gaps = 10/183 (5%)
Query: 9 VLLLLLQPWETQL--QLTGPRCHTGPL--DLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
+++ +L W L Q GP GP+ D+VF++DSS + P F ++ F+ ++ L
Sbjct: 5 LIIFVLIIWTETLADQSPGP----GPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60
Query: 65 NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTM-TGLAIQYAMNV 123
+ N RV + QYS + S F L F R M ++ G++ G A+Q A
Sbjct: 61 PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120
Query: 124 AFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRA 183
FS R ++ P + V++ +D V E + + G++I +VGVQ+A +L+A
Sbjct: 121 YFSAPINGR-DRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKA 179
Query: 184 MAS 186
MA+
Sbjct: 180 MAT 182
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/180 (24%), Positives = 93/180 (51%), Gaps = 2/180 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
DLVF++D S ++ FL + ++V N R+G++ YS+ +++ L++ +
Sbjct: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ + ++ I++L + TG AI FS + G+R + VP++AV+VT D
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQG-VPQIAVLVTHRPSDDE 353
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
V + A R + ++A+ +Q A+ L + S P ++ + ++S+ ++ + +F +L
Sbjct: 354 VHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKL 413
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 6/189 (3%)
Query: 340 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPL 399
++ DLV LVD S N ++ F+ I +DV R+GL+ +S+ +T L
Sbjct: 231 KDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFL 289
Query: 400 GRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 459
T +E +Q + + + TG A+ M FSE+ G+R RA VP++ ++ T
Sbjct: 290 KSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSR-RAQGVPQIAVLVTHR 348
Query: 460 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTM----TH 515
S D++ A + E + ++A+ + A +L EI S P E +S + + T
Sbjct: 349 PSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTK 408
Query: 516 LLENLRGSI 524
L+ L+ I
Sbjct: 409 FLKKLQNEI 417
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/186 (25%), Positives = 90/186 (48%), Gaps = 6/186 (3%)
Query: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 403
+D+V ++D S S++ Q + + +V DV + + G +++S + F L Y
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 404 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
+ + + + T T AL+H F+E G+R + NV ++ +V TDG S D
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQ-NVKQMLIVITDGESHD 930
Query: 464 --DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 521
++ A + +GI ++AVGVGKA + EL +A + + Y +F + + ++
Sbjct: 931 HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988
Query: 522 GSICPE 527
+C E
Sbjct: 989 ERMCTE 994
Score = 58.5 bits (140), Expect = 2e-08
Identities = 41/176 (23%), Positives = 78/176 (44%), Gaps = 4/176 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
CH D++F+ D S V +F TM FL L+ ++ ++G+ Q+ S QS+
Sbjct: 999 CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIE 1058
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L+ + + I+++ A++ N+ F++ G R VP+ V++T
Sbjct: 1059 LKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNM-FNLHAGGR-RNAGVPQTLVVITS 1116
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
G P+ VA+ + GI + +G+ DV + E + + FD ++
Sbjct: 1117 GDPRYDVADAVKTLKDLGICVLVLGI--GDVYKEHLLPITGNSEKIITFQDFDKLK 1170
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 24/183 (13%)
Query: 341 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD------VSPEGTRVGLVQFS---- 390
+ ++D+V L+D S+++ F+ VK V+ ++D + +S G R+ L+ +S
Sbjct: 1959 DSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWES 2018
Query: 391 -----SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMT-GLALRHMVEHSFSEAQGARP 444
V+TEF Y +K + G T G AL E+ F E R
Sbjct: 2019 SRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRK 2078
Query: 445 RALNVPRVGLVFTDGRS---QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAE 501
+V V + G + ++ + + A RAK +G V++ + +G + ++ E+AS P +
Sbjct: 2079 H-----KVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLD 2133
Query: 502 LHV 504
H+
Sbjct: 2134 QHL 2136
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 398
C D++ L DGS V +F + F++ ++D D+ + ++G+ QF S ++
Sbjct: 999 CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIE 1058
Query: 399 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 458
L T + K + V AL+ V + F+ G R R VP+ +V T
Sbjct: 1059 LKNSLTKTQWKTQIQNVSKSGGFPRIDFALK-KVSNMFNLHAGGR-RNAGVPQTLVVITS 1116
Query: 459 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL 502
G + D++ K+ GI + +G+G + L I ++
Sbjct: 1117 GDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKI 1160
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/182 (23%), Positives = 82/182 (45%), Gaps = 18/182 (9%)
Query: 340 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRVGLVQFS--- 390
+E ++D+ L+D S+ V F+ VK F+ ++D+ ++P G RV ++ +S
Sbjct: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345
Query: 391 -------SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 443
V EF L Y + ++K + + + G AL+ +++ F R
Sbjct: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405
Query: 444 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVG-KAVEAELREIASEPAEL 502
+ + + T+ +D + + RAK +G ++ G K + EL E+AS P +
Sbjct: 2406 KNKV-IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDH 2464
Query: 503 HV 504
H+
Sbjct: 2465 HL 2466
Score = 47.0 bits (110), Expect = 5e-05
Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 28/183 (15%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN------ATRVGVIQYS------- 79
+D+ F+ID+S+ V EF+ ++ F+ +L ++ P RV V+ YS
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
Query: 80 ---SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEE 136
V F L ++ M+ ++D L G A+Q+ ++ F P
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVF-----VGTPNL 2404
Query: 137 RVPRVAVIVTDGR----PQDRVAEVAAQARARG--IEIYAVGVQRADVGSLRAMASPPLD 190
R +V +++ G +D + V+ +A+ +G I +++ G + D L +AS PLD
Sbjct: 2405 RKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHND-KELEELASHPLD 2463
Query: 191 EHV 193
H+
Sbjct: 2464 HHL 2466
Score = 44.7 bits (104), Expect = 2e-04
Identities = 39/180 (21%), Positives = 79/180 (43%), Gaps = 24/180 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN------VGPNATRVGVIQYS------- 79
+D+VF+ID+SR++ EF+ ++ + ++ N + + R+ ++ YS
Sbjct: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRR 2021
Query: 80 --SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPEE 136
V++ F + + M+ I+ G T G A+ + F P
Sbjct: 2022 KMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLF-----PETPYL 2076
Query: 137 RVPRVAVIVTDGRPQDR---VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHV 193
R +V +V+ G +R V +A +A+ +G I+ + + + +AS PLD+H+
Sbjct: 2077 RKHKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHL 2136
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/139 (22%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
Query: 338 RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVS----PEGTRVGLVQFSSRV 393
+C +LV +D S V ++F + + IV+ L++ P G RV +V ++S
Sbjct: 1751 KCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGT 1810
Query: 394 RTEFPLGRYGTAAEVKQAVLAVEYME--RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 451
Y ++ Q + ++Y + G A+R + + F NV R
Sbjct: 1811 SYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA----GANVRR 1866
Query: 452 VGLVFTDGRSQDDISVWAA 470
V + F++G++ S+ A
Sbjct: 1867 VAVFFSNGQTASRSSIITA 1885
Score = 38.9 bits (89), Expect = 0.013
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN----ATRVGVIQYSSQV 82
+C P +LVF +D+S V F R + ++ LN+ N RV ++ Y+S
Sbjct: 1751 KCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGT 1810
Query: 83 QSVFPLRAFSRREDMERAIRDL--VPLAQGTMTGLAIQY-AMNVAFSVAEGARPPEERVP 139
+ ++R++ + + + + + G A+++ NV GA V
Sbjct: 1811 SYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA-----NVR 1865
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEI 168
RVAV ++G+ R + + A ++I
Sbjct: 1866 RVAVFFSNGQTASRSSIITATMEFSALDI 1894
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 108 bits (269), Expect = 2e-23
Identities = 70/208 (33%), Positives = 105/208 (50%), Gaps = 8/208 (3%)
Query: 324 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD--VSPEG 381
P R + +C R D+V L+DGS S+ NF V+ F+ +V S +G
Sbjct: 19 PRVRAQHRERVTCTRLYAA--DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQG 76
Query: 382 TRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQG 441
R VQ+S RTEF L G+ +V +A+ + Y T TG A+ H+ +H F Q
Sbjct: 77 VRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLP-QL 135
Query: 442 ARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAE 501
ARP VP+V ++ TDG+SQD + A R K +G+ ++AVG+ A EL+ +AS+P
Sbjct: 136 ARP---GVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTS 192
Query: 502 LHVSYAPDFGTMTHLLENLRGSICPEEG 529
+ DF + LL + +C G
Sbjct: 193 DFFFFVNDFSILRTLLPLVSRRVCTTAG 220
Score = 98.2 bits (243), Expect = 2e-20
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 6/183 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA--TRVGVIQYSSQVQSVFPLRAF 91
D+VF++D S S+ F +R FL GL+ + +A R +QYS ++ F L A
Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
D+ RAIR+L T TG AI + + F + + ARP VP+V +++TDG+ Q
Sbjct: 98 GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVF-LPQLARPG---VPKVCILITDGKSQ 153
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
D V A + + +G++++AVG++ AD L+ +AS P + F V F +++
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213
Query: 212 RLC 214
R+C
Sbjct: 214 RVC 216
Score = 52.8 bits (125), Expect = 9e-07
Identities = 46/167 (27%), Positives = 79/167 (47%), Gaps = 6/167 (3%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQS 84
P C G D+VF+ +++ E R+ L L+ L +GP A +VG++ YS +
Sbjct: 1046 PVCPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSP 1104
Query: 85 VFPLRAFSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
+FPL + + IRD+ + G G A+ A + +A A + VP V V
Sbjct: 1105 LFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHR--YMLAPDAPGRRQHVPGVMV 1162
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
++ D + + +A+A G+ + +G+ AD LR +A P +D
Sbjct: 1163 LLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA-PGMD 1208
Score = 48.9 bits (115), Expect = 1e-05
Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 6/190 (3%)
Query: 339 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 397
C G D+V L ++ E +R + ++V L + P+ +VGL+ +S R F
Sbjct: 1048 CPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLF 1106
Query: 398 PLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 456
PL + Q + + YM+ G G A+ + H + A A R +VP V ++
Sbjct: 1107 PLNGSHDLGIILQRIRDMPYMDPSGNNLGTAV--VTAHRYMLAPDAPGRRQHVPGVMVLL 1164
Query: 457 TDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG-TMTH 515
D + DI A+ G+ + +G+ A +LR +A + +A D G ++
Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224
Query: 516 LLENLRGSIC 525
+ L ++C
Sbjct: 1225 AVSGLATALC 1234
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 104 bits (260), Expect = 2e-22
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 27/228 (11%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTP 275
++ CA HGC C N+PGSY+C C VGFVL D + C + C C H+CV T
Sbjct: 357 VNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTS 416
Query: 276 GGPRCHCREGHDLQPDGRSCQVRDLCNGVDH-GCEFQCVS-EGLSYRCLCPEGRQLQADG 333
GP C C EG L+ DG++C C+ D+ GC CV +S+ C C G LQ D
Sbjct: 417 EGPLCFCPEGSVLERDGKTCSG---CSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDE 473
Query: 334 KSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRV 393
KS C LL S+ +R +F +GT G + S ++
Sbjct: 474 KS---CAASGPQPFLLFANSQDIRHMHF------------------DGTDYGTL-LSQQM 511
Query: 394 RTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQG 441
+ L ++ A A++++ER M G ++E +G
Sbjct: 512 GMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEG 559
Score = 88.2 bits (217), Expect = 2e-17
Identities = 40/110 (36%), Positives = 53/110 (48%)
Query: 230 CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQ 289
C S+ C C G+ L +D++ C ++ C+F NH C C +TPG C C G L
Sbjct: 330 CGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLL 389
Query: 290 PDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRC 339
PDG+ C C C CV C CPEG L+ DGK+C+ C
Sbjct: 390 PDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGC 439
Score = 54.7 bits (130), Expect = 2e-07
Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 206 GLQFQSRLCA-IDLCAEGTHGC---EHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCS 261
G +LC+ ID C G C C+N+ G Y C C G+ Q D C ID C
Sbjct: 860 GFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGY--QGDGIHCLDIDECQ 917
Query: 262 FGNHSC--QHECVSTPGGPRCHC 282
G HSC C +T GG C C
Sbjct: 918 LGEHSCGENASCTNTEGGYTCMC 940
Score = 54.3 bits (129), Expect = 3e-07
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 11/106 (10%)
Query: 225 GCEHH--CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSC---QHECVSTPGGPR 279
GC + C++ C C GF D + C ID C G C +C++T GG
Sbjct: 839 GCSMYARCISEGEDATCQCLKGFA--GDGKLCSDIDECEMGVPVCPPASSKCINTEGGYV 896
Query: 280 CHCREGHDLQPDGRSCQVRDLCNGVDHGC--EFQCVSEGLSYRCLC 323
C C EG+ Q DG C D C +H C C + Y C+C
Sbjct: 897 CRCSEGY--QGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMC 940
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 14/131 (10%)
Query: 217 DLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAID---YCSFGNHSCQHECVS 273
D C GCEH C G+ +C C+ GF+ D ++C A+D + G +++
Sbjct: 743 DPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQV-- 800
Query: 274 TPGGPRCHCREGHDLQPDGRSCQV-------RDLCNGVDHGCEFQCVSEGLSYRCLCPEG 326
TP R D + + V +D C V +C+SEG C C +G
Sbjct: 801 TPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKG 860
Query: 327 RQLQADGKSCN 337
DGK C+
Sbjct: 861 --FAGDGKLCS 869
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 103 bits (258), Expect = 3e-22
Identities = 66/205 (32%), Positives = 109/205 (53%), Gaps = 10/205 (4%)
Query: 327 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 386
+Q QAD K+ D++ LVD S ++ ++F+LV+ F+ +V L V L
Sbjct: 26 QQQQADVKN-----GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFAL 80
Query: 387 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 446
VQF+ TEF L Y T EV + + Y+ TG L ++++ ++A G+R
Sbjct: 81 VQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSR-AG 139
Query: 447 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 506
VP+V +V TDG S+D +++ +A K + ++A+GV A E L+EIASEP +H+
Sbjct: 140 DGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFN 199
Query: 507 APDFGTMTHLLENL----RGSICPE 527
+F ++ ++ NL S+ PE
Sbjct: 200 LENFTSLHDIVGNLVSCVHSSVSPE 224
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/171 (28%), Positives = 102/171 (59%), Gaps = 1/171 (0%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F++DSS ++ F+ +R+FL +++ L VG N ++Q++ + F L +
Sbjct: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
++++ I ++ + TG ++Y M + A G+R + VP+V V++TDG +D
Sbjct: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDG-VPQVIVVLTDGHSKDG 157
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
+A +A+ ++ + ++A+GV+ AD G+L+ +AS PL+ H+F +E+F + +
Sbjct: 158 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHD 208
Score = 95.9 bits (237), Expect = 9e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
Query: 405 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 699 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 757
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 520
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 758 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 812
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P + D+VF+IDSS VRP F +R F+ ++R LN+GP+ RVGV+Q+S+ V
Sbjct: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1487
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L+ + + + AIR L L G+ TG A+++ F + G+R E+ VP+ V
Sbjct: 1488 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1545
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
+V G+ QD V+ A R+ GI VG + D L+ + + P VF V F
Sbjct: 1546 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREF 1599
Score = 87.4 bits (215), Expect = 3e-17
Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V L+D S+ VRP F ++ FV++IV L++ P RVG+VQFS+ V EF L Y +
Sbjct: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1495
Query: 405 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
A V A+ + + TG AL + + F ++ G+R VP+ ++ G+SQD
Sbjct: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQD 1554
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 523
D+S +A + GIV VG EL+ I ++P V +F + ++ E + S
Sbjct: 1555 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREFRELPNIEERIMNS 1612
Query: 524 ICPEEGISAGTELRSP 539
P A + +P
Sbjct: 1613 FGPSAATPAPPGVDTP 1628
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/178 (33%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D++ L+DGS + NF ++ F+ +++ L + + RVG+VQFS RT F L Y T
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
Query: 405 AAEVKQAVLAVEYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 462
A+V AV A+ + G + GLAL +VE+ F+ A G+R VP+V ++ + G S
Sbjct: 302 KAQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSS 359
Query: 463 DDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 520
D+I K+ + + +G A AEL+ IA++ + V P+F + L E L
Sbjct: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 415
Score = 83.6 bits (205), Expect = 5e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 620 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 676
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 677 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 736
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 737 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 793
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 794 SLVYLMDDF 802
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 1026 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 1084
Query: 402 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 1085 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 1143
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 510
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 1144 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 1184
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
Query: 405 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 563
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 517
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 621
Query: 518 ENLR 521
LR
Sbjct: 622 APLR 625
Score = 79.0 bits (193), Expect = 1e-14
Identities = 64/221 (28%), Positives = 108/221 (48%), Gaps = 13/221 (5%)
Query: 337 NRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTE 396
+R + D+V L+DGS + R +F+ V RFV++IVD + + +VGLVQ++S E
Sbjct: 1631 SRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDE 1690
Query: 397 FPLGRYGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 455
F L + T ++ A+ V Y R T + L H+ + F G+R VP++ V
Sbjct: 1691 FFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFV 1749
Query: 456 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMT 514
T G+S +D + + G+ ++AVGV E+ +IAS A V + ++
Sbjct: 1750 ITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELS 1809
Query: 515 -HLLENLRG----SICPEEGISAGTELRSPCECESLVEFQG 550
+LE L ++CP G+ T+ C + ++ F G
Sbjct: 1810 EQVLETLHDAMHETLCP--GV---TDAAKACNLDVILGFDG 1845
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 1230 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1347
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 1348 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1394
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 563
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F+ID S + F + FL+ LL L +G RVGV+Q+S + +++F L +S
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
Query: 94 REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
+ + A++ L A G + GLA+ + + F+ A G+R EE VP+V V+++ G
Sbjct: 302 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSR-VEEGVPQVLVLISAGPSS 359
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D + + + + +G Q A L+ +A+ D VF V F
Sbjct: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF 405
Score = 73.9 bits (180), Expect = 4e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 1025 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 1083
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 1084 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 1142
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 1143 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 1182
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288
Query: 402 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 1347
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 1348 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1385
Score = 67.8 bits (164), Expect = 3e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 341 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 400
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 833 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 891
Query: 401 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 459
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 892 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 950
Query: 460 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 518
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 951 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 1010
Query: 519 NLRGSI 524
NL S+
Sbjct: 1011 NLLKSV 1016
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/154 (25%), Positives = 84/154 (54%), Gaps = 2/154 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S + R F+ + +F+ ++ + ++ +VG++QY+S F L+ FS
Sbjct: 1639 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1698
Query: 94 REDMERAIRDLVPLA-QGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ + AI +V + T + +++ + V V E ++RVP++A ++T G+ +
Sbjct: 1699 KRQIIDAINKVVYKGGRHANTKVGLEH-LRVNHFVPEAGSRLDQRVPQIAFVITGGKSVE 1757
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
+V+ RG++++AVGV+ D + +AS
Sbjct: 1758 DAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS 1791
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 837 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 894
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 895 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 953
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 954 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 990
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
+D+ F++DS+ + F+F M++++ L+R L++ P+ RV V+Q++
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
Query: 82 -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
V+ F L + +E + + + QGT G AI+Y + F A P
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2732
Query: 136 ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
R ++ V++ G P+ ++ E V QA+ +G +G+ ++ ++ + AS P D
Sbjct: 2733 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792
Query: 191 EHVFLVESFDLIQEFGLQFQSRL 213
LV+ + E L RL
Sbjct: 2793 VFFKLVDKSTELNEEPLMRFGRL 2815
Score = 46.2 bits (108), Expect = 8e-05
Identities = 67/284 (23%), Positives = 120/284 (42%), Gaps = 58/284 (20%)
Query: 245 FVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV-RDLCNG 303
F+ +Q+ R + I+ N + H V G R+ D + +C V D+CN
Sbjct: 2542 FLTRQEDR--QLINALQINNTAVGHALVLPAG------RDLTDFLENVLTCHVCLDICN- 2592
Query: 304 VDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFEL 363
+D C F S+R P R +A G + +D+ ++D +++ F
Sbjct: 2593 IDPSCGFG------SWR---PSFRDRRAAGSDVD------IDMAFILDSAETTTLFQFNE 2637
Query: 364 VKRFVNQIVDFLDVSPEG------TRVGLVQFSSR----------VRTEFPLGRYGTAAE 407
+K+++ +V LD+SP+ RV +VQ + V+ EF L YG+ +
Sbjct: 2638 MKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEK 2697
Query: 408 VKQAVLAVEYMERG-------TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
+ V+++ RG G A+ + +E+ F A PR L + + L
Sbjct: 2698 L------VDFLSRGMTQLQGTRALGSAIEYTIENVFESA--PNPRDLKIVVLMLTGEVPE 2749
Query: 461 SQ-DDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAEL 502
Q ++ +AK +G +G+G+ V E+ ASEP ++
Sbjct: 2750 QQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDV 2793
>gi|205277471 cochlin precursor [Homo sapiens]
Length = 550
Score = 103 bits (256), Expect = 6e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 336 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 395
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
Query: 396 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 455
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
Query: 456 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 515
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
Query: 516 LLENLRGSIC 525
++ ++ IC
Sbjct: 533 IVSDVIRGIC 542
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 324 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 383
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
Query: 384 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 443
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
Query: 444 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 492
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
Query: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
Query: 193 VFLVESF 199
F F
Sbjct: 521 AFFTREF 527
Score = 66.2 bits (160), Expect = 8e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
Query: 154 VAEVAAQARARGIEIYAVGVQR 175
+ E AR G+ ++ V V +
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK 303
>gi|4758022 cochlin precursor [Homo sapiens]
Length = 550
Score = 103 bits (256), Expect = 6e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 336 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 395
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
Query: 396 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 455
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
Query: 456 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 515
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
Query: 516 LLENLRGSIC 525
++ ++ IC
Sbjct: 533 IVSDVIRGIC 542
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 324 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 383
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
Query: 384 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 443
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
Query: 444 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 492
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
Query: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
Query: 193 VFLVESF 199
F F
Sbjct: 521 AFFTREF 527
Score = 66.2 bits (160), Expect = 8e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
Query: 154 VAEVAAQARARGIEIYAVGVQR 175
+ E AR G+ ++ V V +
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK 303
>gi|40068485 von Willebrand factor A domain containing 1 isoform 1
[Homo sapiens]
Length = 445
Score = 102 bits (255), Expect = 7e-22
Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
DL+ L+D S SV F V+ FV Q+V L + R LV SR TEFP G++ +
Sbjct: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
Query: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
+ AV A T TGLAL + E F+EA GARP VP+V + TDG S D
Sbjct: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
Query: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 524
+ K+ G+ ++ V G+ EL AS PAE H+ + D + +++ LRGSI
Sbjct: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
Score = 95.5 bits (236), Expect = 1e-19
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)
Query: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
GP DL+F++DSS SV +EF +R+F+ L+ L +G A R ++ S+ +
Sbjct: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
Query: 85 VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
FP S E + A+R T TGLA+ YA F+ A GARP VP+V V
Sbjct: 85 EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141
Query: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
VTDG D V + + G+ ++ V R + L A AS P ++H+ V+ DL
Sbjct: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 102 bits (253), Expect = 1e-21
Identities = 51/133 (38%), Positives = 74/133 (55%), Gaps = 3/133 (2%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
F LQ + C I+ C GC+H C N+ GS+ C C+ G+ L D+R+C+ ID CSF
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSF- 329
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLC 323
+C H C+++PG +C C G+ L C D C+ + C+ CV+ SY C+C
Sbjct: 330 ERTCDHICINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNGSCDQGCVNTKGSYECVC 388
Query: 324 PEGRQLQADGKSC 336
P GR+L +GK C
Sbjct: 389 PPGRRLHWNGKDC 401
Score = 100 bits (250), Expect = 3e-21
Identities = 49/124 (39%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Query: 219 CAEGTHGCEHHCVNSP-GSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGG 277
C HGC H C +P G C C+ GF L Q+Q+ C C++GN CQH C T G
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTG 223
Query: 278 PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCN 337
P C C + + L DGR+C + C + GC+ C RC CP G LQ DGK+C
Sbjct: 224 PTCGCHQKYALHSDGRTCI--ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCK 281
Query: 338 RCRE 341
E
Sbjct: 282 DINE 285
Score = 94.7 bits (234), Expect = 2e-19
Identities = 45/124 (36%), Positives = 66/124 (53%), Gaps = 2/124 (1%)
Query: 203 QEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSF 262
Q++ L R C I+ CA GC+ C ++ C C VGF LQ D ++C+ I+ C
Sbjct: 230 QKYALHSDGRTC-IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLV 288
Query: 263 GNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCL 322
N C H C +T G C CR+G+ L D R+CQ D C+ + C+ C++ S++CL
Sbjct: 289 NNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDHICINSPGSFQCL 347
Query: 323 CPEG 326
C G
Sbjct: 348 CHRG 351
Score = 88.6 bits (218), Expect = 1e-17
Identities = 49/132 (37%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Query: 216 IDLCAEGTHGC--EHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYC--SFGNHSCQHEC 271
+D C+EGT C + C N+P SY C C+ G+ + + + C ID C + N C HEC
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 272 VSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQA 331
++ PG RC C +G L DG +C D C + GC+ CV+ SY C C G L
Sbjct: 92 INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSD 151
Query: 332 DGKSC-NRCREG 342
+ +C +R EG
Sbjct: 152 NQHTCIHRSNEG 163
Score = 84.3 bits (207), Expect = 3e-16
Identities = 43/132 (32%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 205 FGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGN 264
F L + C + C G GC+H C ++ C C + L D R+C I+ C+ N
Sbjct: 193 FDLAQNQKDCTLT-CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNN 249
Query: 265 HSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCP 324
C C T G RC C G LQPDG++C+ + C + GC+ C + S+ C C
Sbjct: 250 GGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCR 309
Query: 325 EGRQLQADGKSC 336
+G +L D ++C
Sbjct: 310 KGYKLLTDERTC 321
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/157 (31%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Query: 197 ESFDLIQEFGLQFQSRLCA-IDLCAEGTH--GCEHHCVNSPGSYFCHCQVGFVLQQDQRS 253
+S+ + + G + + + C ID C + GC H C+N PG+Y C C GF+L D +
Sbjct: 55 KSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHN 114
Query: 254 CRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRD----LCNGVDHGCE 309
C +D C N CQ CV+ G C C G L + +C R C DHGC
Sbjct: 115 CLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCA 174
Query: 310 FQC--VSEGLSYRCLCPEGRQLQADGKSCN-RCREGH 343
C +G C C G L + K C C G+
Sbjct: 175 HICRETPKG-GVACDCRPGFDLAQNQKDCTLTCNYGN 210
Score = 67.4 bits (163), Expect = 3e-11
Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 205 FGLQFQSRLCA-IDLCA-EGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSF 262
+ L R C ID C+ E T C+H C+NSPGS+ C C G++L C +D CS
Sbjct: 312 YKLLTDERTCQDIDECSFERT--CDHICINSPGSFQCLCHRGYILYGTTH-CGDVDECSM 368
Query: 263 GNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLC 301
N SC CV+T G C C G L +G+ C C
Sbjct: 369 SNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKC 407
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 99.0 bits (245), Expect = 1e-20
Identities = 63/197 (31%), Positives = 109/197 (55%), Gaps = 20/197 (10%)
Query: 19 TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQY 78
T++ GP+C PL+LVFVIDSS SV P F+ ++ F+ + + + R+G+I Y
Sbjct: 783 TEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINY 842
Query: 79 SSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERV 138
S +V+ V L+ FS ++D + A+ ++ L +GT T A+Q A + E ARP V
Sbjct: 843 SHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQ----AANDMFEDARP---GV 895
Query: 139 PRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGS-------LRAMASP 187
+VA+++TDG R ++++ EV A +EI+ +GV + + + + +A+
Sbjct: 896 KKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATD 955
Query: 188 PLDEHVFLVESFDLIQE 204
P EHV+ + F +Q+
Sbjct: 956 P--EHVYQFDDFFTLQD 970
Score = 79.7 bits (195), Expect = 7e-15
Identities = 57/202 (28%), Positives = 102/202 (50%), Gaps = 21/202 (10%)
Query: 338 RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEF 397
+C+E ++LV ++D S+SV P+NF+++K FV + D + + R+G++ +S +V
Sbjct: 791 KCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVA 850
Query: 398 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 457
L ++ + + K AV ++Y+ GT T AL + + + ARP V +V LV T
Sbjct: 851 NLKQFSSKDDFKLAVDNMQYLGEGTYTATAL----QAANDMFEDARP---GVKKVALVIT 903
Query: 458 DG----RSQDDISVWAARAKEEGIVMYAVGVGK-------AVEAELREIASEPAELHVSY 506
DG R ++ ++ A + + ++ +GV K E+ IA++P HV
Sbjct: 904 DGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPE--HVYQ 961
Query: 507 APDFGTMTHLL-ENLRGSICPE 527
DF T+ L + L IC +
Sbjct: 962 FDDFFTLQDTLKQKLFQKICED 983
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/222 (21%), Positives = 91/222 (40%), Gaps = 18/222 (8%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGL---LRGLNVGPNA---TRVGVIQYSSQVQSVF 86
+D+VF++DSS S + F+ + F+ L + L G + ++ +Q+SS VQ
Sbjct: 47 IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
P ++ + ++ ++ + + QGT + AI A + R + +V +++T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLL------KREGRKDGVKVVLLMT 160
Query: 147 DGRPQDR---VAEVAAQARARGIEIYAVGVQR-ADVGSLRAMASPPLDEHVFLVESFDLI 202
DG + V ++ AR GI + + + LR ++ E L+ L+
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLV 220
Query: 203 QEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVG 244
+ +Q + + C CE PG H G
Sbjct: 221 DK--IQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPG 260
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSRVRTEF 397
+D+V +VD S+S + F+ K FV+ + D + G ++ +QFSS V+ +
Sbjct: 47 IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106
Query: 398 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 457
P + KQ V ++ + +GT + A+ + + +G + +V L+ T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATR--LLKREGRKDGV----KVVLLMT 160
Query: 458 DG---RSQDDISVWAARAKEEGIVMYAVGVGKAV-EAELREIASE 498
DG D+ + A+ GI + + V EA+LR I+ +
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGD 205
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/126 (38%), Positives = 67/126 (53%), Gaps = 3/126 (2%)
Query: 216 IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTP 275
ID C G C+ C N PGSY C C GF L +D RSC+ ++ C+ N C CV+T
Sbjct: 169 IDECRYGY--CQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATEN-PCVQTCVNTY 225
Query: 276 GGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKS 335
G C C G++L+ DG C D C+ + C+ +CV++ +Y C CP G L D +S
Sbjct: 226 GSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRS 285
Query: 336 CNRCRE 341
C E
Sbjct: 286 CQDINE 291
Score = 94.4 bits (233), Expect = 3e-19
Identities = 58/157 (36%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 185 ASPPLDEHVFLVESFDLIQEFGLQF-QSRLCA-IDLCAEGTHGCE--HHCVNSPGSYFCH 240
A+PPL + S LI FG Q +S C +D CA +H C C+N+ G Y C
Sbjct: 95 AAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCS 154
Query: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
C G+ L + Q C ID C +G CQ C + PG C C G L DGRSCQ +
Sbjct: 155 CTDGYWLLEGQ--CLDIDECRYG--YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNE 210
Query: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCN 337
C ++ C CV+ S+ C C G +L+ DG C+
Sbjct: 211 C-ATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 246
Score = 87.0 bits (214), Expect = 4e-17
Identities = 46/123 (37%), Positives = 63/123 (51%), Gaps = 4/123 (3%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
F L R C ++ CA + C CVN+ GS+ C C G+ L++D C +D CSF
Sbjct: 196 FTLNEDGRSCQDVNECAT-ENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFS 254
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQ--CVSEGLSYRC 321
CQHECV+ PG C C G+ L D RSCQ + C +H C Q C + ++C
Sbjct: 255 EFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Query: 322 LCP 324
+ P
Sbjct: 315 IDP 317
Score = 35.8 bits (81), Expect = 0.11
Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 271 CVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGC--EFQCVSEGLSYRCL 322
C+ +PG + C G DL C D C + C + CV++ Y C+
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCI 69
Score = 33.9 bits (76), Expect = 0.42
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 230 CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHE--CVSTPGGPRC 280
C+ SPG+ C GF L + C ID C +C+ + CV+ GG C
Sbjct: 16 CLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 97.1 bits (240), Expect = 4e-20
Identities = 53/134 (39%), Positives = 75/134 (55%), Gaps = 4/134 (2%)
Query: 205 FGLQFQSRLCA-IDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
F LQ + C ID C GC+H C N+ GS+ C C+ G+ L ++R+C+ ID CSF
Sbjct: 266 FMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSF- 324
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLC 323
+ +C H CV+TPG +C C G+ L C D C+ GC F C++ SY+C C
Sbjct: 325 DRTCDHICVNTPGSFQCLCHRGYLLYGITH-CGDVDECSINRGGCRFGCINTPGSYQCTC 383
Query: 324 PEGR-QLQADGKSC 336
P G+ +L +GK C
Sbjct: 384 PAGQGRLHWNGKDC 397
Score = 95.9 bits (237), Expect = 9e-20
Identities = 48/126 (38%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 219 CAEGTHGCEHHCVNSP-GSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGG 277
C HGC H C +P G C C+ GF L ++QR C+ C++GN CQH C T G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLT--CNYGNGGCQHTCDDTEQG 218
Query: 278 PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC- 336
PRC C L DG++C + C + GC+ +C C CP G LQ D K+C
Sbjct: 219 PRCGCHIKFVLHTDGKTC--IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCK 276
Query: 337 --NRCR 340
+ CR
Sbjct: 277 DIDECR 282
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 204 EFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFG 263
+F L + C I+ CA GC+ C ++ C C VGF+LQ D+++C+ ID C
Sbjct: 226 KFVLHTDGKTC-IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLN 284
Query: 264 NHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLC 323
N C H C +T G C C++G+ L + R+CQ D C+ D C+ CV+ S++CLC
Sbjct: 285 NGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECS-FDRTCDHICVNTPGSFQCLC 343
Query: 324 PEGRQL-------QADGKSCNR--CREGHVD 345
G L D S NR CR G ++
Sbjct: 344 HRGYLLYGITHCGDVDECSINRGGCRFGCIN 374
Score = 90.1 bits (222), Expect = 5e-18
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 6/146 (4%)
Query: 201 LIQEFGLQFQSRLCAIDLCAEGTHGC--EHHCVNSPGSYFCHCQVGFVLQQDQRSCRAID 258
L+ Q+ +D C EGT C + C N+P SY C C+ G+ D + C+ +D
Sbjct: 15 LVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVD 72
Query: 259 YCS-FGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL 317
C N C H+CV+ PG RC C +G L DG +C D C + GC+ CV+
Sbjct: 73 ECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMG 132
Query: 318 SYRCLCPEGRQLQADGKSC-NRCREG 342
SY C C EG L + +C R EG
Sbjct: 133 SYECHCREGFFLSDNQHTCIQRPEEG 158
Score = 89.0 bits (219), Expect = 1e-17
Identities = 54/155 (34%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Query: 198 SFDLIQEFGLQFQSRLCA-IDLCA-EGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCR 255
S+ I + G + C +D C E GC H CVN PG+Y C C GF L D +C
Sbjct: 52 SYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCL 111
Query: 256 AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRD----LCNGVDHGCEFQ 311
+D C+ GN CQ CV+ G CHCREG L + +C R C +HGC
Sbjct: 112 DVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHI 171
Query: 312 C--VSEGLSYRCLCPEGRQLQADGKSCN-RCREGH 343
C +G C C G +L + + C C G+
Sbjct: 172 CRETPKG-GIACECRPGFELTKNQRDCKLTCNYGN 205
Score = 61.2 bits (147), Expect = 2e-09
Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 226 CEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREG 285
C+H CVN+PGS+ C C G++L C +D CS C+ C++TPG +C C G
Sbjct: 328 CDHICVNTPGSFQCLCHRGYLLYGITH-CGDVDECSINRGGCRFGCINTPGSYQCTCPAG 386
Query: 286 HD-LQPDGRSCQVRDLCNG 303
L +G+ C C G
Sbjct: 387 QGRLHWNGKDCTEPLKCQG 405
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 95.9 bits (237), Expect = 9e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492
Query: 405 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 493 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 551
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 520
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 552 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 606
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/176 (35%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P + D+VF+IDSS VRP F +R F+ ++R LN+GP+ RVGV+Q+S+ V
Sbjct: 1222 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1281
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L+ + + + AIR L L G+ TG A+++ F + G+R E+ VP+ V
Sbjct: 1282 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1339
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
+V G+ QD V+ A R+ GI VG + D L+ + + P VF V F
Sbjct: 1340 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREF 1393
Score = 87.4 bits (215), Expect = 3e-17
Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V L+D S+ VRP F ++ FV++IV L++ P RVG+VQFS+ V EF L Y +
Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1289
Query: 405 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
A V A+ + + TG AL + + F ++ G+R VP+ ++ G+SQD
Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQD 1348
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 523
D+S +A + GIV VG EL+ I ++P V +F + ++ E + S
Sbjct: 1349 DVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREFRELPNIEERIMNS 1406
Query: 524 ICPEEGISAGTELRSP 539
P A + +P
Sbjct: 1407 FGPSAATPAPPGVDTP 1422
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/178 (33%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D++ L+DGS + NF ++ F+ +++ L + + RVG+VQFS RT F L Y T
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 405 AAEVKQAVLAVEYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 462
A+V AV A+ + G + GLAL +VE+ F+ A G+R VP+V ++ + G S
Sbjct: 96 KAQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSS 153
Query: 463 DDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 520
D+I K+ + + +G A AEL+ IA++ + V P+F + L E L
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 209
Score = 83.6 bits (205), Expect = 5e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 414 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 531 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 587
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 588 SLVYLMDDF 596
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 820 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 878
Query: 402 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 879 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 937
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 510
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 938 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 978
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 405 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 517
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 415
Query: 518 ENLR 521
LR
Sbjct: 416 APLR 419
Score = 79.0 bits (193), Expect = 1e-14
Identities = 64/221 (28%), Positives = 108/221 (48%), Gaps = 13/221 (5%)
Query: 337 NRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTE 396
+R + D+V L+DGS + R +F+ V RFV++IVD + + +VGLVQ++S E
Sbjct: 1425 SRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDE 1484
Query: 397 FPLGRYGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 455
F L + T ++ A+ V Y R T + L H+ + F G+R VP++ V
Sbjct: 1485 FFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFV 1543
Query: 456 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMT 514
T G+S +D + + G+ ++AVGV E+ +IAS A V + ++
Sbjct: 1544 ITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELS 1603
Query: 515 -HLLENLRG----SICPEEGISAGTELRSPCECESLVEFQG 550
+LE L ++CP G+ T+ C + ++ F G
Sbjct: 1604 EQVLETLHDAMHETLCP--GV---TDAAKACNLDVILGFDG 1639
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 1024 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1141
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1188
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 390
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F+ID S + F + FL+ LL L +G RVGV+Q+S + +++F L +S
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 94 REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
+ + A++ L A G + GLA+ + + F+ A G+R EE VP+V V+++ G
Sbjct: 96 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSR-VEEGVPQVLVLISAGPSS 153
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D + + + + +G Q A L+ +A+ D VF V F
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF 199
Score = 73.9 bits (180), Expect = 4e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 819 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 877
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 878 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 936
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 937 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 976
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 1024 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 402 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 1141
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1179
Score = 67.8 bits (164), Expect = 3e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 341 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 400
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 627 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 685
Query: 401 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 459
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 686 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 744
Query: 460 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 518
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 745 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 804
Query: 519 NLRGSI 524
NL S+
Sbjct: 805 NLLKSV 810
Score = 65.1 bits (157), Expect = 2e-10
Identities = 40/154 (25%), Positives = 84/154 (54%), Gaps = 2/154 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S + R F+ + +F+ ++ + ++ +VG++QY+S F L+ FS
Sbjct: 1433 DIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFST 1492
Query: 94 REDMERAIRDLVPLA-QGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ + AI +V + T + +++ + V V E ++RVP++A ++T G+ +
Sbjct: 1493 KRQIIDAINKVVYKGGRHANTKVGLEH-LRVNHFVPEAGSRLDQRVPQIAFVITGGKSVE 1551
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
+V+ RG++++AVGV+ D + +AS
Sbjct: 1552 DAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS 1585
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 631 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 688
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 689 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 747
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 748 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 784
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
+D+ F++DS+ + F+F M++++ L+R L++ P+ RV V+Q++
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471
Query: 82 -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
V+ F L + +E + + + QGT G AI+Y + F A P
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2526
Query: 136 ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
R ++ V++ G P+ ++ E V QA+ +G +G+ ++ ++ + AS P D
Sbjct: 2527 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2586
Query: 191 EHVFLVESFDLIQEFGLQFQSRL 213
LV+ + E L RL
Sbjct: 2587 VFFKLVDKSTELNEEPLMRFGRL 2609
Score = 46.2 bits (108), Expect = 8e-05
Identities = 67/284 (23%), Positives = 120/284 (42%), Gaps = 58/284 (20%)
Query: 245 FVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV-RDLCNG 303
F+ +Q+ R + I+ N + H V G R+ D + +C V D+CN
Sbjct: 2336 FLTRQEDR--QLINALQINNTAVGHALVLPAG------RDLTDFLENVLTCHVCLDICN- 2386
Query: 304 VDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFEL 363
+D C F S+R P R +A G + +D+ ++D +++ F
Sbjct: 2387 IDPSCGFG------SWR---PSFRDRRAAGSDVD------IDMAFILDSAETTTLFQFNE 2431
Query: 364 VKRFVNQIVDFLDVSPEG------TRVGLVQFSSR----------VRTEFPLGRYGTAAE 407
+K+++ +V LD+SP+ RV +VQ + V+ EF L YG+ +
Sbjct: 2432 MKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEK 2491
Query: 408 VKQAVLAVEYMERG-------TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
+ V+++ RG G A+ + +E+ F A PR L + + L
Sbjct: 2492 L------VDFLSRGMTQLQGTRALGSAIEYTIENVFESA--PNPRDLKIVVLMLTGEVPE 2543
Query: 461 SQ-DDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAEL 502
Q ++ +AK +G +G+G+ V E+ ASEP ++
Sbjct: 2544 QQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDV 2587
>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
sapiens]
Length = 1036
Score = 95.9 bits (237), Expect = 9e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 232 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 291
Query: 405 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 292 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 350
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 520
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 351 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 405
Score = 83.6 bits (205), Expect = 5e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 213 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 269
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 270 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 329
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 330 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 386
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 387 SLVYLMDDF 395
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 619 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 677
Query: 402 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 678 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 736
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 510
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 737 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 777
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 405 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 517
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 214
Query: 518 ENLR 521
LR
Sbjct: 215 APLR 218
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 823 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 940
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 941 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 987
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 73.9 bits (180), Expect = 4e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 618 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 676
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 677 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 735
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 736 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 775
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 342 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 401
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 823 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881
Query: 402 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 460
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 940
Query: 461 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 941 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 978
Score = 67.8 bits (164), Expect = 3e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 341 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 400
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 426 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 484
Query: 401 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 459
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 485 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 543
Query: 460 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 518
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 544 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 603
Query: 519 NLRGSI 524
NL S+
Sbjct: 604 NLLKSV 609
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 430 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 487
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 488 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 546
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 547 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,140,421
Number of Sequences: 37866
Number of extensions: 1010714
Number of successful extensions: 4738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 2311
Number of HSP's gapped (non-prelim): 1384
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.