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Search of human proteins with 13699803
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13699803 WAS protein family, member 3 [Homo sapiens]
(502 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13699803 WAS protein family, member 3 [Homo sapiens] 1030 0.0
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 450 e-126
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 450 e-126
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 450 e-126
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 450 e-126
gi|11386183 WAS protein family, member 2 [Homo sapiens] 446 e-125
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 105 7e-23
gi|150417989 cyclin K isoform 1 [Homo sapiens] 82 9e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 81 3e-15
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 80 3e-15
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 80 3e-15
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 80 3e-15
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 79 7e-15
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 78 2e-14
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 78 2e-14
gi|33356148 formin-like 1 [Homo sapiens] 78 2e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 77 4e-14
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 76 6e-14
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 75 1e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 75 1e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 75 2e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 74 3e-13
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 73 7e-13
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 72 9e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 1e-12
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 72 1e-12
gi|52485606 formin-like 2 [Homo sapiens] 72 2e-12
gi|160707881 formin 2 [Homo sapiens] 72 2e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 72 2e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 71 2e-12
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 1030 bits (2662), Expect = 0.0
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN
Sbjct: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP
Sbjct: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK
Sbjct: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS 240
EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS
Sbjct: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRS 240
Query: 241 HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR 300
HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR
Sbjct: 241 HASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNR 300
Query: 301 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV 360
PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV
Sbjct: 301 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV 360
Query: 361 SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH 420
SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH
Sbjct: 361 SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMH 420
Query: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR
Sbjct: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
Query: 481 RIAVEYSDSDDDSEFDENDWSD 502
RIAVEYSDSDDDSEFDENDWSD
Sbjct: 481 RIAVEYSDSDDDSEFDENDWSD 502
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 450 bits (1157), Expect = e-126
Identities = 279/560 (49%), Positives = 324/560 (57%), Gaps = 63/560 (11%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLVKRNI+PRHLC ALP GI +ELECVTN +LA IIRQLSSLSK+AEDIFGELFNEA+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
+F R NSLQ+R+DRL+V VTQLD EE+SLQDI M+KAF+SST+QDQQ+ + ++P P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
+ + Y+ ++PPPLNILTPYRDD K+GLKFYT+PSYFFDLWKEKMLQDTEDKRKEKR+QK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQ--SVYHGASSEGSLSP 236
QK +D K R +RR+EW +A EL D N L + V +G +S P
Sbjct: 181 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 239
Query: 237 DTRSHASDVTDYSYPATPNHSL----------------HPQPVTPSYAAGDVPPHGPASQ 280
T D YS A P + P P P + AGD P
Sbjct: 240 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 281 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA 332
+A E RP S A+ R P PPPPPP P A S A M P P
Sbjct: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 358
Query: 333 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST 388
P+ PPPP P P V+ A PL P PP +A P HP
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 417
Query: 389 GLLVTAPPPPGPPP-PPPG-------------------------PPGPGSSL--SSSPMH 420
G + PPPP PPP PPPG PGP L S P
Sbjct: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
Query: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
P +E KR P ISDARS LL AIR GIQL+KV+EQREQEAK E + NDVATILSR
Sbjct: 478 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 537
Query: 481 RIAVEYSDSDDDSEFDENDW 500
RIAVEYSDS+DDSEFDE DW
Sbjct: 538 RIAVEYSDSEDDSEFDEVDW 557
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 450 bits (1157), Expect = e-126
Identities = 279/560 (49%), Positives = 324/560 (57%), Gaps = 63/560 (11%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLVKRNI+PRHLC ALP GI +ELECVTN +LA IIRQLSSLSK+AEDIFGELFNEA+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
+F R NSLQ+R+DRL+V VTQLD EE+SLQDI M+KAF+SST+QDQQ+ + ++P P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
+ + Y+ ++PPPLNILTPYRDD K+GLKFYT+PSYFFDLWKEKMLQDTEDKRKEKR+QK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQ--SVYHGASSEGSLSP 236
QK +D K R +RR+EW +A EL D N L + V +G +S P
Sbjct: 181 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 239
Query: 237 DTRSHASDVTDYSYPATPNHSL----------------HPQPVTPSYAAGDVPPHGPASQ 280
T D YS A P + P P P + AGD P
Sbjct: 240 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 281 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA 332
+A E RP S A+ R P PPPPPP P A S A M P P
Sbjct: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 358
Query: 333 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST 388
P+ PPPP P P V+ A PL P PP +A P HP
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 417
Query: 389 GLLVTAPPPPGPPP-PPPG-------------------------PPGPGSSL--SSSPMH 420
G + PPPP PPP PPPG PGP L S P
Sbjct: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
Query: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
P +E KR P ISDARS LL AIR GIQL+KV+EQREQEAK E + NDVATILSR
Sbjct: 478 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 537
Query: 481 RIAVEYSDSDDDSEFDENDW 500
RIAVEYSDS+DDSEFDE DW
Sbjct: 538 RIAVEYSDSEDDSEFDEVDW 557
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 450 bits (1157), Expect = e-126
Identities = 279/560 (49%), Positives = 324/560 (57%), Gaps = 63/560 (11%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLVKRNI+PRHLC ALP GI +ELECVTN +LA IIRQLSSLSK+AEDIFGELFNEA+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
+F R NSLQ+R+DRL+V VTQLD EE+SLQDI M+KAF+SST+QDQQ+ + ++P P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
+ + Y+ ++PPPLNILTPYRDD K+GLKFYT+PSYFFDLWKEKMLQDTEDKRKEKR+QK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQ--SVYHGASSEGSLSP 236
QK +D K R +RR+EW +A EL D N L + V +G +S P
Sbjct: 181 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 239
Query: 237 DTRSHASDVTDYSYPATPNHSL----------------HPQPVTPSYAAGDVPPHGPASQ 280
T D YS A P + P P P + AGD P
Sbjct: 240 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 281 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA 332
+A E RP S A+ R P PPPPPP P A S A M P P
Sbjct: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 358
Query: 333 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST 388
P+ PPPP P P V+ A PL P PP +A P HP
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 417
Query: 389 GLLVTAPPPPGPPP-PPPG-------------------------PPGPGSSL--SSSPMH 420
G + PPPP PPP PPPG PGP L S P
Sbjct: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
Query: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
P +E KR P ISDARS LL AIR GIQL+KV+EQREQEAK E + NDVATILSR
Sbjct: 478 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 537
Query: 481 RIAVEYSDSDDDSEFDENDW 500
RIAVEYSDS+DDSEFDE DW
Sbjct: 538 RIAVEYSDSEDDSEFDEVDW 557
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 450 bits (1157), Expect = e-126
Identities = 279/560 (49%), Positives = 324/560 (57%), Gaps = 63/560 (11%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLVKRNI+PRHLC ALP GI +ELECVTN +LA IIRQLSSLSK+AEDIFGELFNEA+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
+F R NSLQ+R+DRL+V VTQLD EE+SLQDI M+KAF+SST+QDQQ+ + ++P P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
+ + Y+ ++PPPLNILTPYRDD K+GLKFYT+PSYFFDLWKEKMLQDTEDKRKEKR+QK
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPD--NRLSQ--SVYHGASSEGSLSP 236
QK +D K R +RR+EW +A EL D N L + V +G +S P
Sbjct: 181 -QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRP 239
Query: 237 DTRSHASDVTDYSYPATPNHSL----------------HPQPVTPSYAAGDVPPHGPASQ 280
T D YS A P + P P P + AGD P
Sbjct: 240 QTYVDHMD-GSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 281 AAEH--EYRPPS-ASARHMALNRPQQPPPPPP-PQAPEGSQASAPMA----PADYGMLPA 332
+A E RP S A+ R P PPPPPP P A S A M P P
Sbjct: 299 SATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPP 358
Query: 333 QIIEYYNPSGPPPPPP----PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST 388
P+ PPPP P P V+ A PL P PP +A P HP
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP-SPPVARAAPVCETVPVHPLPQ 417
Query: 389 GLLVTAPPPPGPPP-PPPG-------------------------PPGPGSSL--SSSPMH 420
G + PPPP PPP PPPG PGP L S P
Sbjct: 418 GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQ 477
Query: 421 GPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSR 480
P +E KR P ISDARS LL AIR GIQL+KV+EQREQEAK E + NDVATILSR
Sbjct: 478 VIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSR 537
Query: 481 RIAVEYSDSDDDSEFDENDW 500
RIAVEYSDS+DDSEFDE DW
Sbjct: 538 RIAVEYSDSEDDSEFDEVDW 557
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 446 bits (1148), Expect = e-125
Identities = 260/515 (50%), Positives = 321/515 (62%), Gaps = 30/515 (5%)
Query: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
MPLV RNIEPRHLCR LP + SELECVTN TLA +IRQL SLSK+AEDIFGELF +AN
Sbjct: 1 MPLVTRNIEPRHLCRQTLPS-VRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
Query: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
F R +SL +R+DRL VKVTQLD EEVSLQ IN +KAF+SST+QDQ++ +NS+P P
Sbjct: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
Query: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
V + YN D PPPLN LTPYRDD K+ LKFYTDPSYFFDLWKEKMLQDT+D KEKR+ +
Sbjct: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
Query: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKE-LRPDNRLSQSVYHG--ASSEGSLSPD 237
++K+ D R RK + R++EW M +E + +L S Y GS+
Sbjct: 180 KEKK-DNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCV 238
Query: 238 TRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA--SQAAEHEYRPPSASARH 295
AS SYP P P +PS++ ++PP PA S +++ A +
Sbjct: 239 ENVDAS-----SYPPPPQSDSASSP-SPSFSEDNLPP-PPAEFSYPVDNQRGSGLAGPKR 291
Query: 296 MALNRPQQPPPPPPPQAPEGSQ-------ASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
++ P PPP PP +P G + A P P G+ P + G PPPP
Sbjct: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
PP P F +P P PP PA+ T PP TG APPPP PPPPP PP
Sbjct: 352 PPSFP-PHPDFAAP---PPPPPPPAADYPTLPPPPLSQPTG---GAPPPPPPPPPPGPPP 404
Query: 409 GPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKRE 468
P + P PP+++ + + + P +SDARSDLL+AIR G QL++V+EQREQE KR+
Sbjct: 405 PPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRD 463
Query: 469 PVGNDVATILSRRIAVEYSDSDDD-SEFDENDWSD 502
VGNDVATILSRRIAVEYSDS+DD SEFDE+DWSD
Sbjct: 464 VVGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD 498
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 105 bits (263), Expect = 7e-23
Identities = 80/249 (32%), Positives = 106/249 (42%), Gaps = 41/249 (16%)
Query: 280 QAAEHEYRPPSASARHMALNRPQQPPPPP----PPQAPEGSQASAPMAPADYGMLPAQII 335
+A ++E R + + P PPPPP PP P + + P P+
Sbjct: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPS---------- 315
Query: 336 EYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST--GLLVT 393
PPPPPP PS P +M PP PA SS + PP PP + G+
Sbjct: 316 ---RAPTAAPPPPPPSRPSVAVPPPPPNRM-YPPPPPALPSSAPSGPPPPPPSVLGVGPV 371
Query: 394 APPPPGPPPPPPGPPGPGSSLSSSPMHGPPV---------------AEAKRQEPAQPPIS 438
APPPP PPPPPPGPP P L S H P A+ K+ E P+S
Sbjct: 372 APPPPPPPPPPPGPP-PPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVS 430
Query: 439 -DARSDLLAAIRMGIQLKKVQEQREQ----EAKREPVGNDVATILSRRIAVEYSDSDDDS 493
R LL IR GIQLK V + +E A + + ++ +R +S +D+
Sbjct: 431 CSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDED 490
Query: 494 EFDENDWSD 502
E DE D+ D
Sbjct: 491 EDDEEDFED 499
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 82.4 bits (202), Expect = 9e-16
Identities = 95/389 (24%), Positives = 143/389 (36%), Gaps = 65/389 (16%)
Query: 68 SLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFK---SSTVQDQQVVSKNSIPNPVADI 124
SLQ + +AV V L + + +Q+ K ++ VQD V I + + D+
Sbjct: 198 SLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDL 257
Query: 125 YNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKR 184
Y+Q + P + TP++ L + LQ T + ++ Q Q
Sbjct: 258 YSQGKQQMPHH--TPHQ------------------LQQPPSLQPTPQVPQVQQSQPSQSS 297
Query: 185 IDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTRSHASD 244
++ + A+ ++ + ++ ++V E +
Sbjct: 298 EPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPK 357
Query: 245 VTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGP--ASQAAEHEYRPPSASAR-HMALNRP 301
+ P P H + + A G+ P GP A+ + + PP+ A H P
Sbjct: 358 IETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP 417
Query: 302 QQPPPPPPPQ------------APEGSQASAPMAPAD---YGMLPAQI-----IEYYN-- 339
+PPPPPP + EG Q+ M + YG LP + Y+
Sbjct: 418 HRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHV 477
Query: 340 -PSGPPPPP--------PPPVIPSAQTAFVSP--LQMPMQPPFPASASSTHAAPPH-PPS 387
P PPPPP PPP IP + P P PP P THA PPH PP
Sbjct: 478 YPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
Query: 388 TGLLVTAPPPP-----GPPPPPPGPPGPG 411
GL + PPP G PP PP P PG
Sbjct: 538 LGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
Score = 46.6 bits (109), Expect = 5e-05
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 16/152 (10%)
Query: 295 HMALNRPQQPPP-PPPPQAPE-----GSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
H ++ QQPP P PQ P+ SQ+S P P P Q + P+ P P
Sbjct: 267 HHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKD--PQQPAQQQQPAQQPKKPS 324
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
P PS SP Q+ + A PP P + T PP P PPP P
Sbjct: 325 PQ--PS------SPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKP 376
Query: 409 GPGSSLSSSPMHGPPVAEAKRQEPAQPPISDA 440
++L + GP A + PP A
Sbjct: 377 PLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
Score = 31.6 bits (70), Expect = 1.8
Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 9/73 (12%)
Query: 251 PATPNHSLHPQP--VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPP-P 307
P T N + P P + P++A VPPH P PP A +P PPP P
Sbjct: 510 PPTYNPNFPPPPPRLPPTHA---VPPHPPPGLGLPPASYPPPAVPPG---GQPPVPPPIP 563
Query: 308 PPPQAPEGSQASA 320
PP P G A
Sbjct: 564 PPGMPPVGGLGRA 576
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 80.9 bits (198), Expect = 3e-15
Identities = 67/186 (36%), Positives = 78/186 (41%), Gaps = 29/186 (15%)
Query: 252 ATPNHSLHPQPVTPSYAAGDVPPHGPA-SQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
ATP P P A PP P S A + P+A A H+ L P PPP PP
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPV 673
Query: 311 QAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPP--PPVIPSAQTA-------FVS 361
QAP AS P++P+ A P PP PP PP+ PSA
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 362 PLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPP----PPPPGPPGPGSSLSSS 417
PLQ+P PP A+PP PS PPP PP PP PP P +SL S
Sbjct: 734 PLQVPPSPP---------ASPPMSPS-----ATPPPRVPPLLAAPPLQVPPSPPASLPMS 779
Query: 418 PMHGPP 423
P+ PP
Sbjct: 780 PLAKPP 785
Score = 78.6 bits (192), Expect = 1e-14
Identities = 63/195 (32%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 252 ATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPP--PP 309
A P+ P P TPS A PP P + A+ PS +A PQ PP PP
Sbjct: 571 APPSPLTTPPPETPSSIATP-PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629
Query: 310 PQAPEGSQASAPMAP--ADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPM 367
QAP AS P++P P + + + PPP PPV +P P
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV--------QAPFSPPA 681
Query: 368 QPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEA 427
PP SA+ APP A PP PP PP P S + P PP+A
Sbjct: 682 SPPVSPSATPPSQAPPS--------LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 428 KRQEPAQPPISDARS 442
Q P PP S S
Sbjct: 734 PLQVPPSPPASPPMS 748
Score = 75.1 bits (183), Expect = 1e-13
Identities = 68/213 (31%), Positives = 83/213 (38%), Gaps = 31/213 (14%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPP-- 308
P TP+ P P P A P G S PP + +AL Q PP PP
Sbjct: 581 PETPSSIATPPPQAPP-ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 309 PPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPP----------PPVIPSA--- 355
PP +P + +P AP L +++ P PPP PP PPV PSA
Sbjct: 640 PPLSPLAT--PSPQAP---NALAVHLLQ--APFSPPPSPPVQAPFSPPASPPVSPSATPP 692
Query: 356 ----QTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPG 411
+ PLQ+P PP S + PP P + APP PP PP PP
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP---LAAPPLQVPPSPPASPP-MS 748
Query: 412 SSLSSSPMHGPPVAEAKRQEPAQPPISDARSDL 444
S + P P +A Q P PP S S L
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781
Score = 74.7 bits (182), Expect = 2e-13
Identities = 65/199 (32%), Positives = 80/199 (40%), Gaps = 29/199 (14%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPP-HGPASQAAEHEYRPPSASARHMALNRPQQPPPPPP 309
P+ P + P +P + PP P S AA PPS A + P P PP
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMSPSATPP 723
Query: 310 PQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQP 369
PQAP A P P +PS PPP PP++ + PLQ+P P
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPM-----SPSATPPPRVPPLLAA------PPLQVPPSP 772
Query: 370 PFPASASSTHAAPPHPPSTGLLVTAP--PPPGPPPPPPG--PPGPGSSLSSSPMHGPP-- 423
PAS + A P P + L T P P PP PG P P +SL SP+ PP
Sbjct: 773 --PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 424 ----VAEAKRQEPAQPPIS 438
+A Q P PP S
Sbjct: 831 APPVLAAPLLQVPPSPPAS 849
Score = 73.9 bits (180), Expect = 3e-13
Identities = 75/223 (33%), Positives = 87/223 (39%), Gaps = 33/223 (14%)
Query: 248 YSYPATPNHS---LHPQPVTPSYAAG--DVPPHGPASQAAEHEYRPPSASARHMALNRPQ 302
+S PA+P S P PS AA VPP PAS PP + +A Q
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 303 QPPPPP--PPQAPEGSQASAPMAPADYGMLPAQIIEY------YNPSGPPPPPPPPVI-- 352
PP PP PP +P S P P P Q+ +P PPP PP +
Sbjct: 737 VPPSPPASPPMSP--SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 353 PSAQTAFVSPLQMPMQPPFPASAS---STHAAPP--HPP--STGLLVTAPPPPGPP---- 401
P Q P P Q PF SAS S A PP PP + LL P PP P
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 402 PPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDL 444
P P PGP +S+S GP + A P PP S L
Sbjct: 855 PRRPPTPGPDTSVS-----GPRLTLALAPGPPPPPSRSPSSTL 892
Score = 67.0 bits (162), Expect = 4e-11
Identities = 61/186 (32%), Positives = 74/186 (39%), Gaps = 39/186 (20%)
Query: 249 SYPATP--NHSLHPQPVTPSYAAG---DVPPHGPASQAAEHEYRPPSASARHMALNRPQQ 303
S PA+P + S P P P A VPP PAS +PP + +A Q
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
Query: 304 PPPPP---PPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFV 360
P PP P QAP AS PM+P PPP PPV+ +
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPL----------------ATPPPQAPPVLAAPL---- 839
Query: 361 SPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPP-----GPPPPPPGPPGPGSSLS 415
LQ+P PP AS T AP PP+ G + P P PPPP P S+LS
Sbjct: 840 --LQVPPSPP----ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893
Query: 416 SSPMHG 421
+ G
Sbjct: 894 GPDLAG 899
Score = 63.5 bits (153), Expect = 4e-10
Identities = 65/225 (28%), Positives = 78/225 (34%), Gaps = 45/225 (20%)
Query: 260 PQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPP--PPQAPEGSQ 317
P P P A P P S +A PPS + +A Q PP PP PP +P S
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSAT----PPSQAPPSLAAPPLQVPPSPPASPPMSP--SA 720
Query: 318 ASAPMAPADYGMLPAQIIEYYNPSGPPPPP------PPPVIPSAQTAFVSPLQMPMQPPF 371
P AP P Q+ PS P PP PPP +P A PLQ+P PP
Sbjct: 721 TPPPQAPPPLAAPPLQV----PPSPPASPPMSPSATPPPRVPPLLAA--PPLQVPPSPPA 774
Query: 372 PASASSTHAAPPHPP---STGLLVTAPPPPG----------------------PPPPPPG 406
S PP P +T L P PP PP PP
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
Query: 407 PPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMG 451
P + SP P + +R P S + L A+ G
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
Score = 57.4 bits (137), Expect = 3e-08
Identities = 58/201 (28%), Positives = 73/201 (36%), Gaps = 32/201 (15%)
Query: 254 PNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHM-----ALNRP------Q 302
P S P+P T P S A+EH PS +AR L RP
Sbjct: 192 PAPSARPRPPTEG-------PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 303 QPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAF--V 360
P P S P APA P+Q P G PP V P + A +
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAH----PSQP----KPKGLQALRPPQVTPPRKDAAPAL 296
Query: 361 SPLQM-PMQPPFPASASSTHAAPPHPPSTGLLVTAPP-PPGPPPPPPGPPGPGSSLSSSP 418
PL P+ P P+ + PP +T L T PP PP P P PP P + S
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Query: 419 MHGPPVAEAKRQEPAQ--PPI 437
+ PP + P+ PP+
Sbjct: 357 LPSPPATPPSQAPPSMTTPPM 377
Score = 52.0 bits (123), Expect = 1e-06
Identities = 68/253 (26%), Positives = 88/253 (34%), Gaps = 65/253 (25%)
Query: 253 TPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQP----PPPP 308
+P+ P P+ S P QA H + S +L P +P P P
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQAT-HSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 309 PPQAPEGSQAS--------------------------------APMAPADYGMLPAQIIE 336
P QAP AS +P AP ++P +E
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP--LE 513
Query: 337 YYNPSGPP----PP-----PP--------PPVIPSAQTAFVSP-LQMPMQP-PFPASASS 377
+ PP PP PP PP + +A +P L+ P P P P A
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 378 THAAPPHPPSTGLLVTAPPPPGPP----PPPPGPPGPG-SSLSSSPMHGPP-VAEAKRQE 431
+ P PP T + PPP PP PP G P P S L++ P PP +A Q
Sbjct: 574 SPLTTP-PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632
Query: 432 PAQPPISDARSDL 444
P PP S S L
Sbjct: 633 PPSPPASPPLSPL 645
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/227 (26%), Positives = 79/227 (34%), Gaps = 35/227 (15%)
Query: 251 PATPNHSLH------PQPVTPSYAAG---DVPPHGPASQAAEHEYRPPS----ASARHMA 297
P +P+ SL P P P A VPP PAS + RPP+ S
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871
Query: 298 LNRPQQPPPPPPPQAPEGSQASAPMAPADYGML---PAQIIEYYN-PSGPPPPPPPPVIP 353
L P PPPPP S S P P ++ Y + P G PPP
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 928
Query: 354 SAQTAFVSPLQMPMQPPFPASASSTHAAP-PHPPSTGL-----LVT---------APPPP 398
A+ A P P P + AP P PP+TG L T A P P
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988
Query: 399 GPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLL 445
G P P P G ++ G K+ + P+ ++ ++
Sbjct: 989 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVV 1035
Score = 48.9 bits (115), Expect = 1e-05
Identities = 58/202 (28%), Positives = 73/202 (36%), Gaps = 15/202 (7%)
Query: 232 GSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSA 291
G P +RS +S T S PA S P P++ + P QA P
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS---QPKPKGLQALRPPQVTPPR 289
Query: 292 SARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPV 351
AL P P +P G++A P+ P D P +P P P P
Sbjct: 290 KDAAPALGPLSSSPLATP--SPSGTKAR-PVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 352 IPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGP----PPPPPGP 407
PSA + + P PP A S T PPS L T PP P P P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS---LQTIPPIQVPHSLTSPSLQAP 403
Query: 408 PGP--GSSLSSSPMHGPPVAEA 427
P P SSL ++ G P +A
Sbjct: 404 PSPLALSSLQATTSLGSPTLQA 425
Score = 35.8 bits (81), Expect = 0.093
Identities = 33/134 (24%), Positives = 44/134 (32%), Gaps = 35/134 (26%)
Query: 287 RPPSASARHMALNRPQQPPPPPPPQAPE--------GSQASAPMAPADYGMLPAQIIEYY 338
R P+A A + RP P PPPP P G+ P+A G+ A I
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI---- 70
Query: 339 NPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPP 398
P P P ++ +S+ PP++G APP
Sbjct: 71 -----------------------PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 399 GPPPPPPGPPGPGS 412
P P PG S
Sbjct: 108 NTSPGPVSSPGRAS 121
Score = 35.0 bits (79), Expect = 0.16
Identities = 59/262 (22%), Positives = 83/262 (31%), Gaps = 53/262 (20%)
Query: 251 PATPNHSLHPQPVTPSY-----AAGDV---------------------PPHGPASQAAEH 284
P P P PVTP+ AAG V P GP A
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 285 EYRPPSASARHMALNRPQQPPP-----PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYN 339
P S R A R ++ PP P P +P +AS P G +I
Sbjct: 87 SRNPAS---RPPASGRGERAPPAKNTSPGPVSSP--GRASGTTRPGPLGQKGLRISAEET 141
Query: 340 PSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPG 399
+ P ++A + + P P + S A T + + P P
Sbjct: 142 VARGKATEAPK-----RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 400 PPPPPPGPPGPGSSLSSSPMHGP----------PVAEAKRQEPAQPPISDARSDLLAAIR 449
P PP GP S+SS+ H P A Q PA +S + + L + R
Sbjct: 197 RPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 450 MGIQLKKVQEQREQEAKREPVG 471
G + ++ +P G
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKG 276
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 80.5 bits (197), Expect = 3e-15
Identities = 54/154 (35%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Query: 262 PVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAP 321
P PS A VPP P + PP A P PPPPPPP +S P
Sbjct: 565 PSVPSRAP--VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 322 MAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAA 381
P + P + PPPP P V + ++ +P PP P SA
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Query: 382 PPHPPSTGLLVTAPPPPG----PPPPPPGPPGPG 411
PP P S G+ PP PG PPPPPP P GPG
Sbjct: 683 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 716
Score = 73.9 bits (180), Expect = 3e-13
Identities = 61/192 (31%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 266 SYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAP--EGSQASAPMA 323
S G+V + A+ E SA+A + + P + P PP P P G+ P A
Sbjct: 533 SQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPA 592
Query: 324 PADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP----MQPPFPASASSTH 379
P D P PPPPPPPP +P SP +P + PP P S +T
Sbjct: 593 PGD---------STTPPPPPPPPPPPPPLPGG-VCISSPPSLPGGTAISPPPPLSGDAT- 641
Query: 380 AAPPHPPSTGLLVTAP---------PPPGPPP-----PPPGPPGPGSSLSSSPMHGPPVA 425
PP P G+ + +P PPP P P PPP PP PGS + P PP+
Sbjct: 642 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS--AGIPPPPPPLP 699
Query: 426 EAKRQEPAQPPI 437
P PP+
Sbjct: 700 GEAGMPPPPPPL 711
Score = 71.6 bits (174), Expect = 2e-12
Identities = 55/182 (30%), Positives = 63/182 (34%), Gaps = 22/182 (12%)
Query: 263 VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPM 322
V PS + P P PP + P PPPPPPP P G S+P
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 323 APADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAP 382
+ P G PPPP+ A PL + P P+S A P
Sbjct: 623 SL---------------PGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 667
Query: 383 PHPPSTGLLVTAPPPPG-------PPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQP 435
P PP G PPPP PPPPPP P G P+ G P P P
Sbjct: 668 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727
Query: 436 PI 437
I
Sbjct: 728 GI 729
Score = 55.5 bits (132), Expect = 1e-07
Identities = 72/277 (25%), Positives = 92/277 (33%), Gaps = 51/277 (18%)
Query: 159 DLWKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDN 218
DL EK +E ++ +Q + + T EV K+ K + KE+ +
Sbjct: 506 DLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAK--------KEMASLS 557
Query: 219 RLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA 278
+ +V S + P T P P S P P P PP P
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP------PPPPPP 611
Query: 279 SQAAEHEYRPPSASARHMALNRPQQPPP-------PPPPQAPEGSQASAPMA-PADYGML 330
PPS PPP PPPP PEG +P + P +
Sbjct: 612 LPGGVCISSPPSLPGGTAI----SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 667
Query: 331 PAQIIEYYNPSGPPPPP-------PPPVIPSAQTAFVSPLQMPMQ--------PPFPASA 375
P + PPPPP PPP P A + P P+ PPFP
Sbjct: 668 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727
Query: 376 SSTHAAPPHPPSTGLLVTAPPPP---GPPPPPPGPPG 409
PP PP G+ PPPP G P P P G
Sbjct: 728 G----IPPPPPGMGM---PPPPPFGFGVPAAPVLPFG 757
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 20/99 (20%)
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
PP +PS +P PP P + + PP P + T PPPP PPPPPP PP
Sbjct: 564 PPSVPSRAP-------VPPAPPLPGDSGTIIPPPPAPGDS----TTPPPP-PPPPPPPPP 611
Query: 409 GPGSSLSSSP--------MHGPPVAEAKRQEPAQPPISD 439
PG SSP + PP P PP+ +
Sbjct: 612 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 650
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 80.5 bits (197), Expect = 3e-15
Identities = 54/154 (35%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Query: 262 PVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAP 321
P PS A VPP P + PP A P PPPPPPP +S P
Sbjct: 574 PSVPSRAP--VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 322 MAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAA 381
P + P + PPPP P V + ++ +P PP P SA
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Query: 382 PPHPPSTGLLVTAPPPPG----PPPPPPGPPGPG 411
PP P S G+ PP PG PPPPPP P GPG
Sbjct: 692 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
Score = 73.9 bits (180), Expect = 3e-13
Identities = 61/192 (31%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 266 SYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAP--EGSQASAPMA 323
S G+V + A+ E SA+A + + P + P PP P P G+ P A
Sbjct: 542 SQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPA 601
Query: 324 PADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP----MQPPFPASASSTH 379
P D P PPPPPPPP +P SP +P + PP P S +T
Sbjct: 602 PGD---------STTPPPPPPPPPPPPPLPGG-VCISSPPSLPGGTAISPPPPLSGDAT- 650
Query: 380 AAPPHPPSTGLLVTAP---------PPPGPPP-----PPPGPPGPGSSLSSSPMHGPPVA 425
PP P G+ + +P PPP P P PPP PP PGS + P PP+
Sbjct: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS--AGIPPPPPPLP 708
Query: 426 EAKRQEPAQPPI 437
P PP+
Sbjct: 709 GEAGMPPPPPPL 720
Score = 71.6 bits (174), Expect = 2e-12
Identities = 55/182 (30%), Positives = 63/182 (34%), Gaps = 22/182 (12%)
Query: 263 VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPM 322
V PS + P P PP + P PPPPPPP P G S+P
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 323 APADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAP 382
+ P G PPPP+ A PL + P P+S A P
Sbjct: 632 SL---------------PGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 676
Query: 383 PHPPSTGLLVTAPPPPG-------PPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQP 435
P PP G PPPP PPPPPP P G P+ G P P P
Sbjct: 677 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736
Query: 436 PI 437
I
Sbjct: 737 GI 738
Score = 55.5 bits (132), Expect = 1e-07
Identities = 72/277 (25%), Positives = 92/277 (33%), Gaps = 51/277 (18%)
Query: 159 DLWKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDN 218
DL EK +E ++ +Q + + T EV K+ K + KE+ +
Sbjct: 515 DLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAK--------KEMASLS 566
Query: 219 RLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA 278
+ +V S + P T P P S P P P PP P
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP------PPPPPP 620
Query: 279 SQAAEHEYRPPSASARHMALNRPQQPPP-------PPPPQAPEGSQASAPMA-PADYGML 330
PPS PPP PPPP PEG +P + P +
Sbjct: 621 LPGGVCISSPPSLPGGTAI----SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP 676
Query: 331 PAQIIEYYNPSGPPPPP-------PPPVIPSAQTAFVSPLQMPMQ--------PPFPASA 375
P + PPPPP PPP P A + P P+ PPFP
Sbjct: 677 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736
Query: 376 SSTHAAPPHPPSTGLLVTAPPPP---GPPPPPPGPPG 409
PP PP G+ PPPP G P P P G
Sbjct: 737 G----IPPPPPGMGM---PPPPPFGFGVPAAPVLPFG 766
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 20/99 (20%)
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
PP +PS +P PP P + + PP P + T PPPP PPPPPP PP
Sbjct: 573 PPSVPSRAP-------VPPAPPLPGDSGTIIPPPPAPGDS----TTPPPP-PPPPPPPPP 620
Query: 409 GPGSSLSSSP--------MHGPPVAEAKRQEPAQPPISD 439
PG SSP + PP P PP+ +
Sbjct: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 659
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 80.5 bits (197), Expect = 3e-15
Identities = 72/228 (31%), Positives = 88/228 (38%), Gaps = 58/228 (25%)
Query: 300 RPQQPPPPPPPQAPEGSQA------------SAPMAPADYGMLPAQIIEYYNPSGPPPPP 347
R Q+P PPPPP + G+Q S P+ P G+ P P GPPPP
Sbjct: 308 RRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPP----TPRGPPPPG 363
Query: 348 ---PPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPP 404
PPP PP PA+ S PP P + G PPP PPPPP
Sbjct: 364 RGGPPP------------------PPPPATGRSGPLPPPPPGAGG---PPMPPPPPPPPP 402
Query: 405 PGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQE 464
P G G + P P + A P R LL IR GIQL K E
Sbjct: 403 PPSSGNGPAPPPLP---PALVPAGGLAP-----GGGRGALLDQIRQGIQLNKTPGAPESS 454
Query: 465 AKREP-------VGNDVATILSRRIAVEYSDSDDDSEFDE---NDWSD 502
A + P VG + + R A+ SD +D DE ++W D
Sbjct: 455 ALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDEWDD 502
Score = 30.4 bits (67), Expect = 3.9
Identities = 36/131 (27%), Positives = 43/131 (32%), Gaps = 9/131 (6%)
Query: 251 PATPNHSLHPQPVTPSYA-AGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPP 309
P P P P P+ +G +PP P + PP + N P PPP PP
Sbjct: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA-PPPLPP 417
Query: 310 PQAPEGSQASAPMAPADYGMLPAQI---IEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP 366
P G A G L QI I+ G P P + V L
Sbjct: 418 ALVPAGGLAPG----GGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHV 473
Query: 367 MQPPFPASASS 377
MQ A SS
Sbjct: 474 MQKRSRAIHSS 484
Score = 30.0 bits (66), Expect = 5.1
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 16/68 (23%)
Query: 299 NRPQQPPPPPP------------PQAPEGSQASAPMAPADYGMLPAQI----IEYYNPSG 342
+R Q PPPP P P P G Q P+ P G+ I I G
Sbjct: 155 DRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRG 214
Query: 343 PPPPPPPP 350
P P P P
Sbjct: 215 LPAPGPSP 222
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/178 (32%), Positives = 67/178 (37%), Gaps = 36/178 (20%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYR----PPSASARHMALNRPQQPPP 306
P P H QP PPH P H+ + PP S++ + P P
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG--PA 118
Query: 307 PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGP-PPPPPPPVIPSAQTAFVSPLQM 365
P AP S ++ P P G P SGP P P PPP + SA
Sbjct: 119 PGVGSAPPASSSAPPATPPTSGAPPG--------SGPGPTPTPPPAVTSA---------- 160
Query: 366 PMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPP 423
PP A PP PPS+G+ T P GPPPPP PGPG P G P
Sbjct: 161 ---PP--------GAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGP 207
Score = 58.5 bits (140), Expect = 1e-08
Identities = 53/185 (28%), Positives = 68/185 (36%), Gaps = 41/185 (22%)
Query: 276 GPASQAAEHEYRPPSASARHMALNRPQQP-----------PPPPPPQAPEGSQASAPMAP 324
G + H++R P M LN+ + P PP PPP + Q P P
Sbjct: 21 GGGGRGGLHDFRSPPPG---MGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQP 77
Query: 325 ADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP-MQPPFPASASSTHAAPP 383
P Q + P PPPPP S P P + PAS+S+ A PP
Sbjct: 78 PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP 137
Query: 384 H---PPSTGL--------LVTAPPPPGPPPPPP------------GPPGPGSSL---SSS 417
PP +G VT+ PP PPP PP GPP P +++
Sbjct: 138 TSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG 197
Query: 418 PMHGP 422
P GP
Sbjct: 198 PKQGP 202
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/136 (32%), Positives = 47/136 (34%), Gaps = 32/136 (23%)
Query: 309 PPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQ 368
PP +Q PM P P Q SGP PP PPP P Q P Q P Q
Sbjct: 34 PPPGMGLNQNRGPMGPG-----PGQ-------SGPKPPIPPPP-PHQQQQQPPPQQPPPQ 80
Query: 369 PPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEA- 427
P P H PPHP P PPPP ++ P P V A
Sbjct: 81 QPPP------HQPPPHPQ---------PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125
Query: 428 ---KRQEPAQPPISDA 440
PA PP S A
Sbjct: 126 PASSSAPPATPPTSGA 141
Score = 45.8 bits (107), Expect = 9e-05
Identities = 42/150 (28%), Positives = 50/150 (33%), Gaps = 18/150 (12%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
PATP S P P G P PA +A PP+ + + PQ PPPPP
Sbjct: 133 PATPPTSGAP----PGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
Query: 311 QAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPP 370
A G P G ++ P GP P P +P P +PP
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKM-----PGGPKPGGGP--------GLSTPGGHP-KPP 234
Query: 371 FPASASSTHAAPPHPPSTGLLVTAPPPPGP 400
HPP PPP GP
Sbjct: 235 HRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
Score = 33.5 bits (75), Expect = 0.46
Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 14/85 (16%)
Query: 370 PFPASASSTHAAP--PHPPSTGLLVTAPPPP------GPPPPPPGPPGPGSSLSSSPMHG 421
P P + + P P P +G PPPP PPP P P P P
Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP------PPHQP 87
Query: 422 PPVAEAKRQEPAQPPISDARSDLLA 446
PP + +Q+ PP D+ ++A
Sbjct: 88 PPHPQPHQQQQPPPPPQDSSKPVVA 112
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 77.8 bits (190), Expect = 2e-14
Identities = 54/153 (35%), Positives = 66/153 (43%), Gaps = 24/153 (15%)
Query: 301 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNP-------SGPPPPPPPPVIP 353
PQ P P + A+A P D+ + I++ P S PPPPPPPP++P
Sbjct: 373 PQNTTTPKPSVEGQQPAAAAACEPVDHAQSES-ILKVSQPRALEQQASTPPPPPPPPLLP 431
Query: 354 SAQTAFVSPLQMPMQPPFPA-SASSTHAAPPHPPSTGLLVTAPP-PPGPPP--------P 403
+ P P PP P+ A + APP PP GL APP PP PPP P
Sbjct: 432 GSS---AEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLP 488
Query: 404 PPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PP PP PG P PP+ P PP
Sbjct: 489 PPPPPLPGLGCPPPP---PPLLPGMGWGPPPPP 518
Score = 70.9 bits (172), Expect = 3e-12
Identities = 62/225 (27%), Positives = 88/225 (39%), Gaps = 47/225 (20%)
Query: 235 SPDTRSHAS---DVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSA 291
SP ++H S ++ ++P ++ P+P G P A + +H
Sbjct: 351 SPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVE----GQQPAAAAACEPVDHAQSESIL 406
Query: 292 S-ARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPP 350
++ AL + PPPPPP P+ P + + PPPPPPPP
Sbjct: 407 KVSQPRALEQQASTPPPPPP---------PPLLPG-------------SSAEPPPPPPPP 444
Query: 351 VIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPP----STGLLVTAPPP-PG---PPP 402
+PS + P PP P + APP PP S L PPP PG PPP
Sbjct: 445 PLPSVGAKALP--TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502
Query: 403 PPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAA 447
PPP PG G P PP+ PP++ +++ A
Sbjct: 503 PPPLLPGMGWGPPPPP---PPLLPC----TCSPPVAGGMEEVIVA 540
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 77.8 bits (190), Expect = 2e-14
Identities = 54/153 (35%), Positives = 66/153 (43%), Gaps = 24/153 (15%)
Query: 301 PQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNP-------SGPPPPPPPPVIP 353
PQ P P + A+A P D+ + I++ P S PPPPPPPP++P
Sbjct: 373 PQNTTTPKPSVEGQQPAAAAACEPVDHAQSES-ILKVSQPRALEQQASTPPPPPPPPLLP 431
Query: 354 SAQTAFVSPLQMPMQPPFPA-SASSTHAAPPHPPSTGLLVTAPP-PPGPPP--------P 403
+ P P PP P+ A + APP PP GL APP PP PPP P
Sbjct: 432 GSS---AEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLP 488
Query: 404 PPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PP PP PG P PP+ P PP
Sbjct: 489 PPPPPLPGLGCPPPP---PPLLPGMGWGPPPPP 518
Score = 70.9 bits (172), Expect = 3e-12
Identities = 62/225 (27%), Positives = 88/225 (39%), Gaps = 47/225 (20%)
Query: 235 SPDTRSHAS---DVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSA 291
SP ++H S ++ ++P ++ P+P G P A + +H
Sbjct: 351 SPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVE----GQQPAAAAACEPVDHAQSESIL 406
Query: 292 S-ARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPP 350
++ AL + PPPPPP P+ P + + PPPPPPPP
Sbjct: 407 KVSQPRALEQQASTPPPPPP---------PPLLPG-------------SSAEPPPPPPPP 444
Query: 351 VIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPP----STGLLVTAPPP-PG---PPP 402
+PS + P PP P + APP PP S L PPP PG PPP
Sbjct: 445 PLPSVGAKALP--TAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502
Query: 403 PPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAA 447
PPP PG G P PP+ PP++ +++ A
Sbjct: 503 PPPLLPGMGWGPPPPP---PPLLPC----TCSPPVAGGMEEVIVA 540
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 77.8 bits (190), Expect = 2e-14
Identities = 68/201 (33%), Positives = 81/201 (40%), Gaps = 47/201 (23%)
Query: 308 PPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPM 367
P P P GS S +APA E + PPPPPP P +PS Q A P P
Sbjct: 517 PTPGVPTGSP-SPDLAPA---------AEPAPGAAPPPPPPLPGLPSPQEA--PPSAPPQ 564
Query: 368 QPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPP------PPPGPPGPGSSLSSSPMHG 421
PP P S PP PP G L PPPP PPP PPP PP P P G
Sbjct: 565 APPLPGSPEP----PPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPP------PPPGG 614
Query: 422 PPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSRR 481
PP A +R P G++ KK Q R P+ N VA S+
Sbjct: 615 PPDALGRRDSELGP---------------GVKAKK----PIQTKFRMPLLNWVALKPSQI 655
Query: 482 IAVEYSDSDDDSEFDENDWSD 502
+++ +D+ E D SD
Sbjct: 656 TGTVFTELNDEKVLQELDMSD 676
Score = 45.8 bits (107), Expect = 9e-05
Identities = 38/119 (31%), Positives = 44/119 (36%), Gaps = 31/119 (26%)
Query: 232 GSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSA 291
GS SPD A + P P P P PS + PP P QA P
Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPP-----PLPGLPS--PQEAPPSAPP-QAPPLPGSPEPP 575
Query: 292 SARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPP 350
A + + P PPPPPPP +G P+ P PPPPPPPP
Sbjct: 576 PAPPLPGDLPPPPPPPPPPPGTDG-----PVPP------------------PPPPPPPP 611
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/126 (30%), Positives = 44/126 (34%), Gaps = 22/126 (17%)
Query: 340 PSGPPPPPPPPVIPSAQTAFVSPLQ-------------------MPMQPPFPASASS-TH 379
P PP P PSA V L+ +P+ P+ + T
Sbjct: 460 PEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTP 519
Query: 380 AAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPG-SSLSSSPMHGPPVAEAKRQEPAQPPIS 438
P PS L A P PG PPPP PP PG S +P PP A P PP
Sbjct: 520 GVPTGSPSPDLAPAAEPAPGAAPPPP-PPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578
Query: 439 DARSDL 444
DL
Sbjct: 579 PLPGDL 584
Score = 31.6 bits (70), Expect = 1.8
Identities = 21/70 (30%), Positives = 23/70 (32%), Gaps = 14/70 (20%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
P P P+P GD+PP P PP PPPPPPP
Sbjct: 563 PQAPPLPGSPEPPPAPPLPGDLPPPPPPPPP------PPGTDG--------PVPPPPPPP 608
Query: 311 QAPEGSQASA 320
P G A
Sbjct: 609 PPPPGGPPDA 618
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 77.0 bits (188), Expect = 4e-14
Identities = 63/205 (30%), Positives = 74/205 (36%), Gaps = 50/205 (24%)
Query: 252 ATPNHSLHPQPVTPS-----YAAGDVPPH---------GPASQAAEHEYRPPSASARHMA 297
A P P P P + AG PP GP + PP +
Sbjct: 210 AVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP-- 267
Query: 298 LNRPQQPPPPPP-PQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP---PPPPVIP 353
NR +PPPP P P G P+ P P + Y P GPPPP PPPP
Sbjct: 268 -NRGDRPPPPVLFPGQPFGQPPLGPLPPGP----PPPVPGYGPPPGPPPPQQGPPPP--- 319
Query: 354 SAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPG------P 407
P P +PP P T A PPH P PPPG PPP P P
Sbjct: 320 --------PGPFPPRPPGPLGPPLTLAPPPHLPG--------PPPGAPPPAPHVNPAFFP 363
Query: 408 PGPGSSLSSSPMHGPPVAEAKRQEP 432
P S + +S GPP + + P
Sbjct: 364 PPTNSGMPTSDSRGPPPTDPYGRPP 388
Score = 49.7 bits (117), Expect = 6e-06
Identities = 52/179 (29%), Positives = 61/179 (34%), Gaps = 36/179 (20%)
Query: 270 GDVPPHGPASQAA-----EHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAP 324
G P G +S+AA R P A P P PPPP + P+ P
Sbjct: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP 243
Query: 325 ADYGMLPAQIIEYYNPSGPPPPPPP-PVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPP 383
P GPP PPPP V+P P +PP P P
Sbjct: 244 P-------------GPPGPPGPPPPGQVLPPP---LAGPPNRGDRPPPPV------LFPG 281
Query: 384 HPPSTGLLVTAPPPPGPPPP----PPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPIS 438
P L PP P PP P PPGPP P P PP + P PP++
Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPP----RPPGPLGPPLT 336
Score = 33.1 bits (74), Expect = 0.60
Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 10/98 (10%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
P P P P P G PP GP PP A L P PPP
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP-- 353
Query: 311 QAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
AP + A P P + GM + + GPPP P
Sbjct: 354 -APHVNPAFFP-PPTNSGMPTS------DSRGPPPTDP 383
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 76.3 bits (186), Expect = 6e-14
Identities = 64/215 (29%), Positives = 75/215 (34%), Gaps = 53/215 (24%)
Query: 274 PHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPPPPPQAP--EGSQASAPMAPAD 326
P GP Q PP + NRPQ PPPP PQ P +G ++ +P +P
Sbjct: 97 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPG 156
Query: 327 YGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVS----PLQMPMQPPFPASASSTHAAP 382
P P GPPPPP P P Q P P PP S + +P
Sbjct: 157 KPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215
Query: 383 PH-----PPSTGLLVTAPPPP----------------GPPPP------------------ 403
P PP G PPPP GPPPP
Sbjct: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275
Query: 404 -PPGPP-GPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PPG P GP ++P PP A Q+P PP
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
Score = 74.7 bits (182), Expect = 2e-13
Identities = 66/216 (30%), Positives = 79/216 (36%), Gaps = 43/216 (19%)
Query: 261 QPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPPPPPQAP-- 313
Q +PS AG+ P GP+ Q PP + N+PQ PPPP PQ P
Sbjct: 25 QEESPSLIAGN--PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
Query: 314 EGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAF----VSPLQMPMQP 369
+G ++ +P +P P P GPPPPP P P Q P P P
Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
Query: 370 PFPASASSTHAAPPH-----PPSTGLLVTAPPPP-----GPPP----------PPPGPPG 409
P S + +PP PP G PPPP GPPP PP P G
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
Query: 410 P---------GSSLSSSPMHGPPVAEAKRQEPAQPP 436
P S P PP + Q P PP
Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Score = 64.3 bits (155), Expect = 2e-10
Identities = 51/175 (29%), Positives = 65/175 (37%), Gaps = 14/175 (8%)
Query: 274 PHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPPPPPQAP--EGSQASAPMAPAD 326
P GP Q PP + +PQ PPPP PQ P +G ++ + +P
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 327 YGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVS----PLQMPMQPPFPASASSTHA-A 381
P P GPPPPP P P Q P P PP + S A +
Sbjct: 218 KPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS 276
Query: 382 PPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PP P P GPPPP G P + + GPP + P++PP
Sbjct: 277 PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RPPQGGRPSRPP 330
Score = 39.7 bits (91), Expect = 0.006
Identities = 33/129 (25%), Positives = 37/129 (28%), Gaps = 32/129 (24%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPP---HGPASQAAEHEYRPPSASARHMAL-----NRPQ 302
P P P P + PP GP Q PP + N+PQ
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Query: 303 QPPPPPPPQAP------------------------EGSQASAPMAPADYGMLPAQIIEYY 338
PPPP PQ P EG+ P PA Q
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312
Query: 339 NPSGPPPPP 347
P GPP PP
Sbjct: 313 QPQGPPRPP 321
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 75.5 bits (184), Expect = 1e-13
Identities = 76/279 (27%), Positives = 94/279 (33%), Gaps = 88/279 (31%)
Query: 225 YHGASSEGSLSPDTRSHASDVTDYSYPA---TPNHSLHP-------------QPVTPSYA 268
YHG G P H+ + +P T H HP QP P
Sbjct: 379 YHGMHGGGPGGPGGGPHS-----FPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMN 433
Query: 269 AGDVPP--HGPASQAAEHEYRPPSASARHMALNRPQQPPPP----PPPQAPEGSQASAPM 322
G PP HGP P + + + PPPP PPP P Q P
Sbjct: 434 QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP- 492
Query: 323 APADYGMLPAQIIEYYNPSGPPPP-------PPPPVIPSAQTAFVSPLQMPMQ------- 368
PSGP PP PPPP PS+ A +PL
Sbjct: 493 -----------------PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTS 535
Query: 369 ------PPFPASASSTHAAPPHPPSTGLLVTAPPPPG---------PPPPPPGPPGPGSS 413
PP+ ++ A+P P G P PPG PPPPPP PPG
Sbjct: 536 AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG---- 591
Query: 414 LSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGI 452
S+ M+ PP P PP D S+ + + MG+
Sbjct: 592 -SAGMMYAPP--------PPPPPPMDP-SNFVTMMGMGV 620
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 16/65 (24%)
Query: 368 QPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPP--PPPPG--------PPGPGSSLSSS 417
+ P PAS ST P+T L +AP P P PPPP PP S S S
Sbjct: 322 EAPVPASVGSTSG-----PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSES 376
Query: 418 -PMHG 421
P HG
Sbjct: 377 RPYHG 381
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 75.5 bits (184), Expect = 1e-13
Identities = 70/230 (30%), Positives = 87/230 (37%), Gaps = 27/230 (11%)
Query: 229 SSEGSLSPDTRSHASDVTDYSYP--ATPNHSLHPQ--PVTPSYAAGDVP-----PHGPAS 279
SS +L+ D S P A P PQ P P G P P GP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73
Query: 280 QAAEHEYRPPSASARHMALNRPQQPPPPPPPQAP--EGSQASAPMAPADYGMLPAQIIEY 337
+ + PP N+PQ PPPP PQ P +G ++ +P +P P
Sbjct: 74 PPGKPQGPPPQGG------NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ-GG 126
Query: 338 YNPSGPPPPP-----PPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLV 392
P GPPPPP PPP + P + PP + S + +PP P
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Query: 393 TAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARS 442
P GPPPPP P GP + P PP K Q P PP D +S
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQGP--PPQGDNKS 232
Score = 74.3 bits (181), Expect = 2e-13
Identities = 64/220 (29%), Positives = 74/220 (33%), Gaps = 61/220 (27%)
Query: 274 PHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPP-----PPPQAPEGSQASAPMA 323
P GP Q PP + N+PQ PPPP PPPQ SQ++
Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP 239
Query: 324 PADYGMLPAQIIEYYNPSGPPPPP-------------------------PPPVIPSAQTA 358
G P + P GPPPPP PPP S +
Sbjct: 240 GKPQGPPPQGGNQ---PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 359 FVSPLQMPMQPPFPASASSTHAAPPHP-------PSTGLLVTAPPPPGPP--PPPPG--- 406
SP P PP P + PP P P G PPPPG P PPP G
Sbjct: 297 SRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 407 ----------PPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
P GP ++P PP A Q+P PP
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Score = 70.5 bits (171), Expect = 3e-12
Identities = 61/193 (31%), Positives = 69/193 (35%), Gaps = 40/193 (20%)
Query: 274 PHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPP-----PPPQAPEGSQASAPMA 323
P GP Q PP + N+PQ PPPP PPPQ S++S
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177
Query: 324 PADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPA---------- 373
G P + P GPPPPP P P Q P PP P
Sbjct: 178 GKPQGPPPQGGNQ---PQGPPPPPGKPQGPPPQGG-----NKPQGPPPPGKPQGPPPQGD 229
Query: 374 ----SASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKR 429
SA S P PP G P GPPPPP P GP + P PP K
Sbjct: 230 NKSQSARSPPGKPQGPPPQG----GNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKP 283
Query: 430 QEPAQPPISDARS 442
Q P PP ++S
Sbjct: 284 QGP--PPQGGSKS 294
Score = 68.2 bits (165), Expect = 2e-11
Identities = 57/192 (29%), Positives = 73/192 (38%), Gaps = 17/192 (8%)
Query: 260 PQPVTPSYAAGDVP--PHGPASQAAEHEYRPPSASARHMAL-----NRPQQPPPPPPPQA 312
PQ S +A P P GP Q PP + N+PQ PPPP PQ
Sbjct: 226 PQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285
Query: 313 PE---GSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP-----PPPVIPSAQTAFVSPLQ 364
P GS++ + +P P P GPPPPP PPP + P +
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 344
Query: 365 MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPV 424
PP S S + +PP P P GPPPP G P + + GPP
Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP- 403
Query: 425 AEAKRQEPAQPP 436
+ P++PP
Sbjct: 404 RPPQGGRPSRPP 415
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 74.7 bits (182), Expect = 2e-13
Identities = 57/218 (26%), Positives = 80/218 (36%), Gaps = 36/218 (16%)
Query: 235 SPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASAR 294
+P + + V + P TP + P P++ A +PP
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP-------------------- 826
Query: 295 HMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPS 354
+ P P P PPP P+ A P+ +P+ + + S PPPP PP + S
Sbjct: 827 ----SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMES 880
Query: 355 AQTAFVSPLQMPMQPPF--------PASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPG 406
V P PP P+S P PP LV PPPP P P PP
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 407 PPGPGSSLSSSPMHGPPVAEAKRQEPA--QPPISDARS 442
PP P +S + P +K P +PP + R+
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978
Score = 71.2 bits (173), Expect = 2e-12
Identities = 73/275 (26%), Positives = 100/275 (36%), Gaps = 78/275 (28%)
Query: 234 LSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPAS-------------Q 280
++P T S S P P P P P + P G A+
Sbjct: 616 VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675
Query: 281 AAEHE---YRPPSASARHMALNRPQ----------QPPPPPPPQAPEGSQAS---APMAP 324
A++H ++PP+ +PQ PPPPPPP P + A AP AP
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735
Query: 325 A--DYGMLPAQI----IEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQP----PFPAS 374
+ + P + +++ PP PPPPP IP+ P Q P +P P P S
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL-----PPQAPPKPLVTIPAPTS 790
Query: 375 ASS-----THAAPPHP-------------PSTGLLVTAPPPPGPPPPP----------PG 406
+ T AAPP P P++ + + P PP P PPP
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850
Query: 407 PPGPGSSLSS------SPMHGPPVAEAKRQEPAQP 435
PP P S + S S PP A +P +P
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885
Score = 64.3 bits (155), Expect = 2e-10
Identities = 67/231 (29%), Positives = 85/231 (36%), Gaps = 72/231 (31%)
Query: 258 LHPQP--VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEG 315
L PQP VTP A+ PP P PP P PPPPPPP P
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPPPPP-----PP-----------PPPPPPPPPPPLPSQ 652
Query: 316 SQASAPMA-------------------------PADYGMLPAQIIE---YYNPSGP-PPP 346
S SA A P ++ +Q ++ P+G PPP
Sbjct: 653 SAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP 712
Query: 347 PPPPVIPSAQTAFVSPLQMPMQPPFPASASS------------THAAPPHPPSTGLLVTA 394
PPPP P+ +A P P P ++ T APP PP
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP-------- 764
Query: 395 PPPPGPPP-PPPGPPGPGSSL---SSSPMHGPPVAEAKRQEPAQPPISDAR 441
PPPP P P PP PP P ++ +S+ P V +A P PP+ A+
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT-PPVPPAK 814
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 24/85 (28%)
Query: 338 YNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP 397
Y PP P P ++ P+ AS S PP PP PPP
Sbjct: 602 YTSLVPPLSPQPKIV----------------TPYTASQPSPPLPPPPPP--------PPP 637
Query: 398 PGPPPPPPGPPGPGSSLSSSPMHGP 422
P PPPPPP PP P S S+ P
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAP 662
Score = 33.9 bits (76), Expect = 0.35
Identities = 47/198 (23%), Positives = 70/198 (35%), Gaps = 36/198 (18%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
P TP + + S A P P+ + ++ PP+ S + ++ PPP PP
Sbjct: 972 PPTPQRN---SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG---SPSKETLPPPAAPP 1025
Query: 311 QAPEGSQASAPM------------APADYGMLPAQIIEYYNPSGPPPPPPPP-------- 350
+ + + + + AP G ++E+ +P PPPP
Sbjct: 1026 KPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP 1085
Query: 351 --VIPSAQTAFVSPLQMPMQP-PFPASASSTHAAPP-----HPPSTGLLVT--APPPPGP 400
IP+ + SP + P P S S APP ST L + P
Sbjct: 1086 PIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMA 1145
Query: 401 PPPPPGPPGPGSSLSSSP 418
P P P SSLS P
Sbjct: 1146 TVVPQVPTSPKSSLSVQP 1163
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.9 bits (180), Expect = 3e-13
Identities = 61/195 (31%), Positives = 70/195 (35%), Gaps = 22/195 (11%)
Query: 252 ATPNHSLHPQP-VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
ATP+ S P P PS PP P SQA P + + P P PPP
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 311 QAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP---PPPVIPSA------QTAFVS 361
QAP AP P+ PP P P P P+A Q F
Sbjct: 356 QAPPALALPPLQAPPS------------PPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 362 PLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHG 421
P P+Q PF AS + PPS A PP PP PP P S + P
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 422 PPVAEAKRQEPAQPP 436
PP+A Q PP
Sbjct: 464 PPLAAPPLQLAKPPP 478
Score = 72.0 bits (175), Expect = 1e-12
Identities = 77/240 (32%), Positives = 89/240 (37%), Gaps = 53/240 (22%)
Query: 252 ATPNHSLHPQPVTPSYAAGDVPPHGPA-SQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
ATP P P A PP P S A + P+A A H+ L P PPP PP
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPV 409
Query: 311 QAPEGSQASAPM---------APADYGMLPAQIIEY------YNPSGPPPPPPPPVI--- 352
QAP AS P+ AP P Q+ +PS PPP PP +
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469
Query: 353 --------PSAQTAFVSP---------LQMPMQPPFPASAS---STHAAPP--HPP--ST 388
P A A +P P Q PF SAS S A PP PP +
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 389 GLLVTAPPPPGPP----PPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDL 444
LL P PP P P P PGP +S+S GP + A P PP S L
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-----GPRLTLALAPGPPPPPSRSPSSTL 584
Score = 66.6 bits (161), Expect = 5e-11
Identities = 69/247 (27%), Positives = 86/247 (34%), Gaps = 48/247 (19%)
Query: 232 GSLSPDTRSHASDVTDYSYPA--------TPNHSLHPQPVTPSYAAGDVPPH-------- 275
G P +RS +S T S PA TP HP P PP
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 283
Query: 276 ----GPASQ---AAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYG 328
GP S A PPS SA P PP PP QA + +P A +
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS-PPATPPSQAT--TSLGSPTLQATHS 340
Query: 329 MLPAQIIEYYNPSGPPPP--PPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPH-- 384
LP+ + +P PPP PP +P Q P P+ P S + +A H
Sbjct: 341 FLPSPPL---SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 385 ------PPSTGLLVTAPPPPGPP------PPPPGPP---GPGSSLSSSPMHGPPVAEAKR 429
PPS + PP PP PP PP P + SP PP++ +
Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 430 QEPAQPP 436
P PP
Sbjct: 458 PPPQAPP 464
Score = 65.9 bits (159), Expect = 8e-11
Identities = 61/189 (32%), Positives = 76/189 (40%), Gaps = 25/189 (13%)
Query: 248 YSYPATPNHS---LHPQPVTPSYAAG--DVPPHGPASQAAEHEYRPPSASARHMALNRPQ 302
+S PA+P S P PS AA VPP PAS PP + +A Q
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472
Query: 303 --QPPPPPPPQAPEGSQASAPMAPADY-GMLPAQIIEYY--NPSGPPPPPPPPVIPSAQT 357
+PPP PP + P PA + G P +P PPP PPV+ +
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL- 531
Query: 358 AFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPP-----GPPPPPPGPPGPGS 412
LQ+P PP AS T AP PP+ G + P P PPPP P S
Sbjct: 532 -----LQVPPSPP----ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582
Query: 413 SLSSSPMHG 421
+LS + G
Sbjct: 583 TLSGPDLAG 591
Score = 62.4 bits (150), Expect = 9e-10
Identities = 62/191 (32%), Positives = 81/191 (42%), Gaps = 39/191 (20%)
Query: 265 PSYAAGDVPPHG-----PASQAAEHEYRPPSASARH--MALNRPQQPPPPPPPQAPEGSQ 317
PS AA P G PAS++ P S+ AR A P+ P P P+ P+G Q
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQ 269
Query: 318 ASAP---------MAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQ 368
A P APA G L + + +PS PP P PP S QT +P
Sbjct: 270 ALRPPQVTPPRKDAAPA-LGPLSSSPLATPSPSAPPSPSAPP---SLQT-------LPSP 318
Query: 369 PPFPASASSTHAAPPHPPSTGLLVTAPP-PPGPPPPPPGPPGPGSSLSSSPMHGPPVAEA 427
P P S ++T P +T + +PP P PPP PP +L+ P+ PP
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP----ALALPPLQAPP---- 370
Query: 428 KRQEPAQPPIS 438
PA PP+S
Sbjct: 371 --SPPASPPLS 379
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/227 (26%), Positives = 79/227 (34%), Gaps = 35/227 (15%)
Query: 251 PATPNHSLH------PQPVTPSYAAG---DVPPHGPASQAAEHEYRPPS----ASARHMA 297
P +P+ SL P P P A VPP PAS + RPP+ S
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563
Query: 298 LNRPQQPPPPPPPQAPEGSQASAPMAPADYGML---PAQIIEYYN-PSGPPPPPPPPVIP 353
L P PPPPP S S P P ++ Y + P G PPP
Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 620
Query: 354 SAQTAFVSPLQMPMQPPFPASASSTHAAP-PHPPSTGL-----LVT---------APPPP 398
A+ A P P P + AP P PP+TG L T A P P
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 680
Query: 399 GPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLL 445
G P P P G ++ G K+ + P+ ++ ++
Sbjct: 681 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVV 727
Score = 39.7 bits (91), Expect = 0.006
Identities = 57/253 (22%), Positives = 78/253 (30%), Gaps = 68/253 (26%)
Query: 287 RPPSASARHMALNRPQQPPPPPPPQAP--------EGSQASAPMAPADYGMLPAQIIEYY 338
R P+A A + RP P PPPP P G+ P+A G+ A I E
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 339 NPSGPPPPPPPPV------IPSAQTAFVSPLQMPMQP-----PFPASASSTHAAPPHPPS 387
+GP PP P A+ P+ P + P P + +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 388 TGLLVTAP---------------PPPGPPPPP----------------------PGPP-- 408
G AP P PG P P P PP
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 409 GPGSSLSSSPMHGP----------PVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQ 458
GP S+SS+ H P A Q PA +S + + L + R G +
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254
Query: 459 EQREQEAKREPVG 471
++ +P G
Sbjct: 255 RAPAHPSQPKPKG 267
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 72.8 bits (177), Expect = 7e-13
Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 36/217 (16%)
Query: 254 PNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASA------RHMALNRPQQPPP- 306
P+ P P P+ AA V P GP S PP+ +++ Q PPP
Sbjct: 674 PSKPRSPNPAAPALAAPAVVP-GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732
Query: 307 -------PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAF 359
PPPP AP A ++ P Q +P+ PPPPPP P A
Sbjct: 733 PPPSYHPPPPPTKKPEVVVEAPSA-SETAEEPLQ-----DPNWPPPPPPAPEEQDLSMAD 786
Query: 360 VSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPP--PPGPPPPPPGPPGPGSSL 414
P + + P PA S + P ++ TA PPG P PPP PP P +
Sbjct: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPA- 845
Query: 415 SSSPMHGPPVAEAKRQEP------AQPPISDARSDLL 445
SS+P H VA+ ++EP PP D + L+
Sbjct: 846 SSAPGH---VAKLPQKEPVGCSKGGGPPREDVGAPLV 879
Score = 53.1 bits (126), Expect = 6e-07
Identities = 57/219 (26%), Positives = 75/219 (34%), Gaps = 46/219 (21%)
Query: 229 SSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRP 288
S S+S S S +D PA P+ PQ +TP +PPH
Sbjct: 621 SPGASVSSSLTSLCSSSSD---PA-PSDRSGPQILTPLGDRFVIPPH------------- 663
Query: 289 PSASARHMALNRPQQPPP-PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP 347
P+ P P PPP P +AP A ++P + PP P
Sbjct: 664 ------------PKVPAPFSPPPSKPRSPNPAAPALAAP-AVVPGPVSTTDASPQSPPTP 710
Query: 348 PPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAP-----------P 396
+ P ++ +S Q P P P S H PP ++V AP
Sbjct: 711 QTTLTPLQESPVISKDQSPPPSPPP----SYHPPPPPTKKPEVVVEAPSASETAEEPLQD 766
Query: 397 PPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQP 435
P PPPPPP P S++ P EPA P
Sbjct: 767 PNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP 805
Score = 50.8 bits (120), Expect = 3e-06
Identities = 68/269 (25%), Positives = 82/269 (30%), Gaps = 84/269 (31%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPS--------ASARHMALNRPQ 302
P TP +L P +P + PP P+ + H PP+ A + P
Sbjct: 707 PPTPQTTLTPLQESPVISKDQSPP--PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL 764
Query: 303 QPP--PPPPPQAPEGSQAS-APMAPADYGMLPAQIIEYYNPSGPPP-------------- 345
Q P PPPPP APE S A P + E PSG P
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA 824
Query: 346 --------PPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVT---- 393
P PPP P+ A +P + P S PP LVT
Sbjct: 825 LQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL 884
Query: 394 -------APPPPGPPPPPPGP------------------PGPGS---------------- 412
P G P P GP P P S
Sbjct: 885 QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944
Query: 413 -SLSSSPMHGPPVAEAKRQEPAQPPISDA 440
LSS+ +GPP AE + P Q P S A
Sbjct: 945 EGLSSAQPNGPPEAEPR---PPQSPASTA 970
Score = 43.9 bits (102), Expect = 3e-04
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 29/185 (15%)
Query: 285 EYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPP 344
E +P S++A + + PQ P ++AS ++ G L + + PP
Sbjct: 439 EGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP 498
Query: 345 PPP---------------PPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTG 389
PPP P +P P Q+P +PP + AAP P
Sbjct: 499 PPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP-QLP-RPPTTGGSEGAGAAPCPPNPAN 556
Query: 390 LLVTAPPPPGPPPPPPGP-----PGPG-SSLSSSP------MHGPPVAEAKRQEPAQPPI 437
V P G PP P P G SS S +P + GPP + K Q P +
Sbjct: 557 SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERV 616
Query: 438 SDARS 442
+ RS
Sbjct: 617 TSLRS 621
Score = 39.3 bits (90), Expect = 0.008
Identities = 52/208 (25%), Positives = 68/208 (32%), Gaps = 33/208 (15%)
Query: 229 SSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRP 288
S E +LSP + + T P P L P +P A P R
Sbjct: 573 SPERTLSPSSGYSSQSGT----PTLPPKGLAGPPASPGKAQ-------PPKPERVTSLRS 621
Query: 289 PSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
P AS +L P P G Q P+ D ++P +P P P P
Sbjct: 622 PGASVSS-SLTSLCSSSSDPAPSDRSGPQILTPLG--DRFVIPP------HPKVPAPFSP 672
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
PP P + L P P P S +T A+P PP+ +T P
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVS--TTDASPQSPPTPQTTLT-----------PLQE 719
Query: 409 GPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
P S SP PP + P + P
Sbjct: 720 SPVISKDQSPPPSPPPSYHPPPPPTKKP 747
Score = 35.8 bits (81), Expect = 0.093
Identities = 42/160 (26%), Positives = 58/160 (36%), Gaps = 33/160 (20%)
Query: 289 PSASARHM--ALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP 346
PSA + + AL+ P P P + A A G+ AQ P+GPP
Sbjct: 905 PSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQ------PNGPPEA 958
Query: 347 PP-PPVIPSAQTAFVSP-------LQMPMQPPFPASA---------SSTHAAPPHPPSTG 389
P PP P++ +F+ L+ P+ P A S + PP P
Sbjct: 959 EPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKS 1018
Query: 390 LLVTAPPPP------GPPPPPPGPPGPGSSLSSSPMHGPP 423
APPP G PPP L++ P +G P
Sbjct: 1019 --PKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056
Score = 33.1 bits (74), Expect = 0.60
Identities = 51/209 (24%), Positives = 69/209 (33%), Gaps = 25/209 (11%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPP-- 308
P HSLH + + +PP Q + RPP+ A P P P
Sbjct: 500 PPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLP-RPPTTGGSEGAGAAPCPPNPANSW 558
Query: 309 -----------PPQAPEG--SQASAPMAPADYGMLPAQIIEYYNPSGPPPPP--PPPVIP 353
PP++PE S +S + + LP + + +GPP P P P
Sbjct: 559 VPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGL-----AGPPASPGKAQPPKP 613
Query: 354 SAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPP--PGPPGPG 411
T+ SP +SS+ AP +L PP P P P P
Sbjct: 614 ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP 673
Query: 412 SSLSSSPMHGPPVAEAKRQEPAQPPISDA 440
S SP P A P +DA
Sbjct: 674 PSKPRSPNPAAPALAAPAVVPGPVSTTDA 702
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 72.4 bits (176), Expect = 9e-13
Identities = 67/223 (30%), Positives = 78/223 (34%), Gaps = 44/223 (19%)
Query: 251 PATPNHSLHPQPVTPSYAAGD------VPPHGPASQAAEHEYRPPSASARHMALNRPQQP 304
P P P P+ P + V P GP ++ PP A P P
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA-------PPPP 226
Query: 305 PPPPPPQAPEGSQAS-----------APM------------APADYGMLPAQIIEYYNPS 341
PPPPPP P AS AP+ P Y L A+ +
Sbjct: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286
Query: 342 GPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPP 401
PP PPPP+ P A SP PP P SS+ PP PP + P G
Sbjct: 287 QEPPAPPPPLPPYASC---SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
Query: 402 --PPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARS 442
P PP PPG L HG P A + P PP ARS
Sbjct: 344 ALPAPPAPPGSQPFLQKK-RHGRPGAGGGKLNP--PPAPPARS 383
Score = 59.3 bits (142), Expect = 8e-09
Identities = 60/223 (26%), Positives = 82/223 (36%), Gaps = 65/223 (29%)
Query: 227 GASSEGSLSPDTRSHAS-----DVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQA 281
G + EG S +TR ++ D+ +P +P AG GP S+A
Sbjct: 78 GTNKEGGGSANTRGASTPPTLGDLFAGGFPVL-------RPAGQRDVAGGKTGQGPGSRA 130
Query: 282 AEHEYRPPSASARHMALNRPQQPPPPPP---PQAPEGSQASAPMAPADYGMLPAQIIEYY 338
PS + ++ P PP P G+ +AP P
Sbjct: 131 -------PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRP-------------- 169
Query: 339 NPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASA--SSTHAAPPHPPSTGLLVTAPP 396
N PPPP PPP P P+ PP P+S+ + +PP P + G L P
Sbjct: 170 NVPAPPPPTPPPPPP------------PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
Query: 397 PPGPPPPPPGPP--------GPGSSLSS-------SPMHGPPV 424
P PPPP PP P S LS +P+H PP+
Sbjct: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
Score = 53.9 bits (128), Expect = 3e-07
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 2/95 (2%)
Query: 342 GPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPP 401
GP P P +P+ + PL P P ++ + AA PP + PP P PP
Sbjct: 125 GPGSRAPSPRLPNKTIS--GPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP 182
Query: 402 PPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PPP PP P SS +P+ PP K P P
Sbjct: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 395 PPPPGPPPPPPGPPGPGSSLSSSPMHGPPV----AEAKRQEPAQPPISDARSDLLAAIRM 450
P PP PPPP P PP P + P PPV + +R +P RS LLA I+
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADP------KGRSALLADIQQ 55
Query: 451 GIQLKKVQEQREQEA 465
G +L+KV + ++ A
Sbjct: 56 GTRLRKVTQINDRSA 70
Score = 31.6 bits (70), Expect = 1.8
Identities = 17/50 (34%), Positives = 17/50 (34%), Gaps = 23/50 (46%)
Query: 304 PPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIP 353
PPPPPPP P P G PPPPPP P
Sbjct: 4 PPPPPPPLPPPPP-----------------------PLGAPPPPPPSAPP 30
Score = 29.6 bits (65), Expect = 6.7
Identities = 14/30 (46%), Positives = 14/30 (46%)
Query: 301 PQQPPPPPPPQAPEGSQASAPMAPADYGML 330
P PPPPPP AP SAP D L
Sbjct: 9 PPLPPPPPPLGAPPPPPPSAPPVSTDTSSL 38
Score = 29.6 bits (65), Expect = 6.7
Identities = 25/91 (27%), Positives = 33/91 (36%), Gaps = 13/91 (14%)
Query: 236 PDTRSHASDVTDYSYPATP-----NHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPS 290
P +AS S PA P + S P P+ P + PP +QA PP
Sbjct: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
Query: 291 AS--------ARHMALNRPQQPPPPPPPQAP 313
+ R A PPP PP ++P
Sbjct: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 72.0 bits (175), Expect = 1e-12
Identities = 77/240 (32%), Positives = 89/240 (37%), Gaps = 53/240 (22%)
Query: 252 ATPNHSLHPQPVTPSYAAGDVPPHGPA-SQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
ATP P P A PP P S A + P+A A H+ L P PPP PP
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPV 448
Query: 311 QAPEGSQASAPM---------APADYGMLPAQIIEY------YNPSGPPPPPPPPVI--- 352
QAP AS P+ AP P Q+ +PS PPP PP +
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508
Query: 353 --------PSAQTAFVSP---------LQMPMQPPFPASAS---STHAAPP--HPP--ST 388
P A A +P P Q PF SAS S A PP PP +
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 389 GLLVTAPPPPGPP----PPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDL 444
LL P PP P P P PGP +S+S GP + A P PP S L
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-----GPRLTLALAPGPPPPPSRSPSSTL 623
Score = 70.5 bits (171), Expect = 3e-12
Identities = 63/206 (30%), Positives = 73/206 (35%), Gaps = 24/206 (11%)
Query: 241 HASDVTDYSYPATPNHSLHPQP-VTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALN 299
H+S +T ATP P P PS PP P SQA P + +
Sbjct: 326 HSSSLT--CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
Query: 300 RPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP---PPPVIPSA- 355
P P PPPQAP AP P+ PP P P P P+A
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPS------------PPASPPLSPLATPSPQAPNAL 431
Query: 356 -----QTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGP 410
Q F P P+Q PF AS + PPS A PP PP PP P
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 411 GSSLSSSPMHGPPVAEAKRQEPAQPP 436
S + P PP+A Q PP
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPP 517
Score = 65.9 bits (159), Expect = 8e-11
Identities = 61/189 (32%), Positives = 76/189 (40%), Gaps = 25/189 (13%)
Query: 248 YSYPATPNHS---LHPQPVTPSYAAG--DVPPHGPASQAAEHEYRPPSASARHMALNRPQ 302
+S PA+P S P PS AA VPP PAS PP + +A Q
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511
Query: 303 --QPPPPPPPQAPEGSQASAPMAPADY-GMLPAQIIEYY--NPSGPPPPPPPPVIPSAQT 357
+PPP PP + P PA + G P +P PPP PPV+ +
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL- 570
Query: 358 AFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPP-----GPPPPPPGPPGPGS 412
LQ+P PP AS T AP PP+ G + P P PPPP P S
Sbjct: 571 -----LQVPPSPP----ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 413 SLSSSPMHG 421
+LS + G
Sbjct: 622 TLSGPDLAG 630
Score = 63.2 bits (152), Expect = 5e-10
Identities = 75/269 (27%), Positives = 96/269 (35%), Gaps = 67/269 (24%)
Query: 232 GSLSPDTRSHASDVTDYSYPA-----------TPNHSLHPQP----------VTP----- 265
G P +RS +S T S PA P H P+P VTP
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 266 SYAAGDV---PPHGPASQAAEHEYRPPSASAR--------HMALNRPQQPPPP------- 307
+ A G + P P+ AA PP+ A +A P PP P
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352
Query: 308 --PPPQAPEGSQAS----APMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVS 361
P P A SQA+ +P A + LP+ + +P PPP PP + +
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL---SPLATPPPQAPPALA------LP 403
Query: 362 PLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPP-----GPPG--PGSSL 414
PLQ P PP S P P+ + P PPP PP PP P S
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 415 SSSPMHGPP-VAEAKRQEPAQPPISDARS 442
++ P PP +A Q P PP S S
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/227 (26%), Positives = 79/227 (34%), Gaps = 35/227 (15%)
Query: 251 PATPNHSLH------PQPVTPSYAAG---DVPPHGPASQAAEHEYRPPS----ASARHMA 297
P +P+ SL P P P A VPP PAS + RPP+ S
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602
Query: 298 LNRPQQPPPPPPPQAPEGSQASAPMAPADYGML---PAQIIEYYN-PSGPPPPPPPPVIP 353
L P PPPPP S S P P ++ Y + P G PPP
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 659
Query: 354 SAQTAFVSPLQMPMQPPFPASASSTHAAP-PHPPSTGL-----LVT---------APPPP 398
A+ A P P P + AP P PP+TG L T A P P
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719
Query: 399 GPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLL 445
G P P P G ++ G K+ + P+ ++ ++
Sbjct: 720 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVV 766
Score = 38.5 bits (88), Expect = 0.014
Identities = 53/188 (28%), Positives = 68/188 (36%), Gaps = 20/188 (10%)
Query: 273 PPHGPASQAAEHEYRPPSASARHMALNRPQQPPPP-PPPQAPEGSQASAPMAPADYGMLP 331
P G S A R A+ + L RP P PP + P S +SA +++
Sbjct: 167 PTPGTPSPAMARRSR---AAGTEVGLPRPAPSARPRPPTEGPRKSVSSA----SEHSTTE 219
Query: 332 AQIIEYYNPS--GPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHP--PS 387
PS G P + S+ T SP + SA T AP HP P
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG------PSARGTPRAPAHPSQPK 273
Query: 388 TGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGP-PVAEAKRQEPAQPPISDARSDLLA 446
L PP PP P G LSSSP+ P P A + Q P P + S L
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 447 AIRMGIQL 454
+ + L
Sbjct: 333 QLATPLPL 340
Score = 35.8 bits (81), Expect = 0.093
Identities = 33/134 (24%), Positives = 44/134 (32%), Gaps = 35/134 (26%)
Query: 287 RPPSASARHMALNRPQQPPPPPPPQAPE--------GSQASAPMAPADYGMLPAQIIEYY 338
R P+A A + RP P PPPP P G+ P+A G+ A I
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI---- 70
Query: 339 NPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPP 398
P P P ++ +S+ PP++G APP
Sbjct: 71 -----------------------PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 399 GPPPPPPGPPGPGS 412
P P PG S
Sbjct: 108 NTSPGPVSSPGRAS 121
Score = 29.6 bits (65), Expect = 6.7
Identities = 59/257 (22%), Positives = 76/257 (29%), Gaps = 86/257 (33%)
Query: 251 PATPNHSLHPQPVTPSY-----AAGDV---------------------PPHGPASQAAEH 284
P P P PVTP+ AAG V P GP A
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 285 EYRPPSASARHMALNRPQQPPP-----PPPPQAPEGSQASAPMAPADYGMLPAQIIEYY- 338
P S R A R ++ PP P P +P +AS P G +I
Sbjct: 87 SRNPAS---RPPASGRGERAPPAKNTSPGPVSSP--GRASGTTRPGPLGQKGLRISAEET 141
Query: 339 ---------------------NPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASS 377
+ SGP P P P + A + + +P P
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP------- 194
Query: 378 THAAPPHPPSTG----------LLVTAPPPPGPPPPPPG-----PPGPGSSLSSSPMHGP 422
+A P PP+ G T P P P G P S S++P+ P
Sbjct: 195 --SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 423 ----PVAEAKRQEPAQP 435
P A + PA P
Sbjct: 253 ARSGPSARGTPRAPAHP 269
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 72.0 bits (175), Expect = 1e-12
Identities = 62/176 (35%), Positives = 71/176 (40%), Gaps = 33/176 (18%)
Query: 288 PPSASARHMALNRPQQP-----PPPPP-----PQAPEGSQASAPMAPADYGMLPAQIIEY 337
PPS A + RP P PP PP P P G PM P G P+
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPT--GPAPS----- 272
Query: 338 YNPSGPP--PPPPPPVIPSAQTAFVSPLQMPMQPPFPA---SASSTHAAPP--HPPSTGL 390
P GPP PPP P V P A V P + PP P A H P HPP++G+
Sbjct: 273 -GPPGPPQLPPPAPGVHPPAPV--VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGV 329
Query: 391 LVTAP----PPPGPPPPPP--GPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDA 440
AP P PG PP P PP PG + +H PP A Q P P + A
Sbjct: 330 HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPA 385
Score = 50.4 bits (119), Expect = 4e-06
Identities = 60/214 (28%), Positives = 73/214 (34%), Gaps = 27/214 (12%)
Query: 249 SYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPP 308
S P P L P+ P+ A PP P PP A H + P P
Sbjct: 250 SLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPP-APVVHPPASGVHPPAPGV 308
Query: 309 PPQAPEGSQASAPMAPADYGMLP-AQIIEYYNPSGPPP-----PPPPPVIPSAQTAFVSP 362
P AP + + P G+ P A + P PP PP P V P A P
Sbjct: 309 HPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368
Query: 363 LQ--MPMQPPFPASASSTHAAPP--HPPSTGLLVTAP-----PP----------PGPPPP 403
P P +A + H P HPP+ G+ AP PP P PP
Sbjct: 369 SAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGV 428
Query: 404 PPGPPGPGSSLSSSPMHGPPV-AEAKRQEPAQPP 436
P PG PM PP+ +E P PP
Sbjct: 429 HPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 46.6 bits (109), Expect = 5e-05
Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 14/107 (13%)
Query: 337 YYNPSGPPPPPPPPVIPSAQTAFVSPLQ--MPMQPPFPASASSTHAAPPHPPSTGLLV-- 392
++ PP PP P P PL +P +PP P S P PP GL +
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESL-------PPPPPGGLPLPP 263
Query: 393 ---TAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
T P P GPP PP PP +P+ PP + P P
Sbjct: 264 MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHP 310
Score = 45.8 bits (107), Expect = 9e-05
Identities = 44/151 (29%), Positives = 53/151 (35%), Gaps = 38/151 (25%)
Query: 295 HMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPS 354
H + +P P PP P P G + P P G+ P + P PPPPP +
Sbjct: 211 HFKMEKP--PAPPSLPAGPPGVKRPPP--PLMNGLPPRPPL----PESLPPPPPGGL--- 259
Query: 355 AQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPP--------- 405
PL PM P PA + PP PP PP PG PP P
Sbjct: 260 -------PLP-PMPPTGPAPSG-----PPGPPQL-----PPPAPGVHPPAPVVHPPASGV 301
Query: 406 GPPGPGSSLSSSPMHGPPVAEAKRQEPAQPP 436
PP PG + +H P PP
Sbjct: 302 HPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP 332
Score = 37.4 bits (85), Expect = 0.032
Identities = 43/142 (30%), Positives = 52/142 (36%), Gaps = 38/142 (26%)
Query: 260 PQPVTPSYAAGDVPP----HGPASQAAEHEYRP---PSASARHMALNRPQQPPPPPPPQA 312
P P A G PP H P S A H P P+A A H P P PQA
Sbjct: 346 PAPGVHPPAPGVHPPAPGVHPPPS-AGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQA 404
Query: 313 ------PEGSQASAP-MAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQM 365
P G SAP + P G+ P+ NP PP P PP+
Sbjct: 405 PGVHPQPPGVHPSAPGVHPQPPGVHPS------NPGVHPPTPMPPM-------------- 444
Query: 366 PMQPPFPASASSTHAAPPHPPS 387
++PP P+ PP PP+
Sbjct: 445 -LRPPLPSEGPGN--IPPPPPT 463
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 71.6 bits (174), Expect = 2e-12
Identities = 53/178 (29%), Positives = 75/178 (42%), Gaps = 38/178 (21%)
Query: 315 GSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPAS 374
G+ M A G LP PPPPP PP + +T P+ PM PP
Sbjct: 511 GNSVGPTMGAASSGPLP-----------PPPPPLPPSSDTPETVQNGPVTPPMPPP---- 555
Query: 375 ASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQ 434
PP PP PPPP PPPPPP PGP + +P PP+ P+
Sbjct: 556 -------PPPPP-------PPPPPPPPPPPPPLPGPAAETVPAPPLAPPL-------PSA 594
Query: 435 PPISDARSDLLAAIRMGIQLKKVQEQREQEAKREPVGNDVATILSRRIAVEYSDSDDD 492
PP+ S + G+ K+++ + + R PV N VA ++ +++ DD+
Sbjct: 595 PPLPGTSSPTV-VFNSGLAAVKIKKPIKTKF-RMPVFNWVALKPNQINGTVFNEIDDE 650
Score = 52.4 bits (124), Expect = 1e-06
Identities = 59/238 (24%), Positives = 91/238 (38%), Gaps = 67/238 (28%)
Query: 166 LQDTEDKRK------EKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKE--LRPD 217
LQDTE++ EK+ + K +D RE+ K A + M +KE ++
Sbjct: 409 LQDTENEAMSKIVELEKQLMQRNKELD-VVREIYK--DANTQVHTLRKMVKEKEEAIQRQ 465
Query: 218 NRLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQ--------PVTPSYAA 269
+ L + + H +G++ + D+ A+ S+ + P + ++
Sbjct: 466 STLEKKI-HELEKQGTIKIQKKGDG-DIAILPVVASGTLSMGSEVVAGNSVGPTMGAASS 523
Query: 270 GDVPPHGPASQAAEHEYRPPSASARHMALN------RPQQPPPPPPPQAPEGSQASAPMA 323
G +PP P PPS+ N P PPPPPPP P
Sbjct: 524 GPLPPPPPPL--------PPSSDTPETVQNGPVTPPMPPPPPPPPPPPPP---------- 565
Query: 324 PADYGMLPAQIIEYYNPSGPPPPPPPPVI-PSAQTAFVSPL--QMPMQPPFPASASST 378
PPPPPPPP+ P+A+T PL +P PP P ++S T
Sbjct: 566 -------------------PPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPT 604
Score = 31.2 bits (69), Expect = 2.3
Identities = 53/272 (19%), Positives = 99/272 (36%), Gaps = 48/272 (17%)
Query: 67 NSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNPVADIYN 126
N+ +R++ L ++ L +++ +A ++Q++ +N + V +IY
Sbjct: 389 NAALERVEELEENISHLSEKLQDTE------NEAMSKIVELEKQLMQRNKELDVVREIYK 442
Query: 127 QSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQKEQKRID 186
D ++ L +K++ ++ ++ L+ + +++ K QK+ D
Sbjct: 443 --DANTQVHTLRKMVKEKEEAIQ------------RQSTLEKKIHELEKQGTIKIQKKGD 488
Query: 187 GTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGASSEGSLSPDTR----SHA 242
G + V ++ E+ N + ++ GA+S G L P S
Sbjct: 489 GDIAILPVVASGT--------LSMGSEVVAGNSVGPTM--GAASSGPLPPPPPPLPPSSD 538
Query: 243 SDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQ 302
+ T + P TP P P P PP P PP A P
Sbjct: 539 TPETVQNGPVTP-----PMPPPPPPPPPPPPPPPPP---------PPPPLPGPAAETVPA 584
Query: 303 QPPPPPPPQAPEGSQASAPMAPADYGMLPAQI 334
P PP P AP S+P + G+ +I
Sbjct: 585 PPLAPPLPSAPPLPGTSSPTVVFNSGLAAVKI 616
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 71.6 bits (174), Expect = 2e-12
Identities = 71/235 (30%), Positives = 91/235 (38%), Gaps = 35/235 (14%)
Query: 226 HGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAA----GDVPPHGPASQA 281
H S+E S + ++ + P+ P P P T S ++ G VPP P
Sbjct: 831 HSISTEFQTSHEHSVSSAFKNSCNIPSPP-----PLPCTESSSSMPGLGMVPPPPPPLPG 885
Query: 282 AEHEYRPPSASARHMALNRPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPS 341
P +A + L + PPPPPP G P+ A G+LP +
Sbjct: 886 MTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA--GILPLPPLP--GAG 941
Query: 342 GPPPPP-------PPPVIPSAQTAFVSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLL 391
PPPPP PPP +P A PL +P PP P + PP PP G
Sbjct: 942 IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG-----IPPPPPLPGAG 996
Query: 392 VTAPPP-PGPP-PPPPGPPGPGSSLSSSPMHG----PPVAEAKRQEPAQPPISDA 440
+ PPP PG PPPP PG G P+ G PP P PP+ A
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050
Score = 68.6 bits (166), Expect = 1e-11
Identities = 69/224 (30%), Positives = 84/224 (37%), Gaps = 46/224 (20%)
Query: 254 PNHSLHPQPVTPSYA-------AGDVPPHGPASQ-AAEHEYRPPSASARHMALNRPQQPP 305
P S+ P PS G PPH +++ HE+ SA + N P PP
Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKN--SCNIPSPPP 860
Query: 306 ----------------PPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP--- 346
PPPPP P + + P P Q E P PP P
Sbjct: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPP-PLQGTEMLPPPPPPLPGAG 919
Query: 347 -PPPPVIPSAQTAFVSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PGPP 401
PPPP +P A + PL +P PP P +A PP PP G + PPP PG
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAA-----IPPPPPLPGAGIPLPPPLPGAG 974
Query: 402 -PPPPGPPGPGSSLSSSPMHG----PPVAEAKRQEPAQPPISDA 440
PPPP PG G P+ G PP P PP+ A
Sbjct: 975 IPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Score = 67.0 bits (162), Expect = 4e-11
Identities = 69/234 (29%), Positives = 89/234 (38%), Gaps = 47/234 (20%)
Query: 249 SYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPP 308
S+ T + S P P + ++AG P + E++ + A P PP
Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
Query: 309 PPQAPEGSQAS------APMAPADYGM----LPAQIIEYYNP-------SGPPPP----- 346
P E S + P P GM LP+ I P PPPP
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919
Query: 347 -PPPPVIPSAQTAFVSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PG-- 399
PPPP +P A + PL +P PP P + A PP PP G + PPP PG
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA-----AIPPPPPLPGAGIPLPPPLPGAG 974
Query: 400 -PPPP-------PPGPPGPGSSL-SSSPMHG----PPVAEAKRQEPAQPPISDA 440
PPPP PP PP PG+ + P+ G PP P PP+ A
Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1028
Score = 65.5 bits (158), Expect = 1e-10
Identities = 65/207 (31%), Positives = 80/207 (38%), Gaps = 40/207 (19%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPP----- 305
P P + P P P AG PP P A PP A P PP
Sbjct: 1056 PPLPGAGIPPPPPLPG--AGIPPP--PPLPGAGIPPPPPLPGA-----GIPPPPPLPGVG 1106
Query: 306 -PPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQ 364
PPPPP G P+ A G+ P + +G PPPPP P + +
Sbjct: 1107 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLP---GAGIPPPPPLPRVGIPPPPPLPGAG 1161
Query: 365 MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PG----PPPP------PPGPPGPGSS 413
+P PP P + PP PP G+ + PPP PG PPPP PP PP PG
Sbjct: 1162 IPPPPPLPGAG-----IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216
Query: 414 LSSSPMHGPPVAEAKRQEPAQP--PIS 438
+ +P PP+ P P P+S
Sbjct: 1217 IPPAP--APPLPPPGTGIPPPPLLPVS 1241
Score = 65.1 bits (157), Expect = 1e-10
Identities = 59/193 (30%), Positives = 73/193 (37%), Gaps = 33/193 (17%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPP----P 306
P P + P P P +PP P A PP + + P P P
Sbjct: 1067 PPLPGAGIPPPPPLPG---AGIPPPPPLPGAGI----PPPPPLPGVGIPPPPPLPGAGIP 1119
Query: 307 PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP-----PPPVIPSAQTAFVS 361
PPPP G P+ A G+ P + PPP P PPP +P A
Sbjct: 1120 PPPPLPGAGIPPPPPLPGA--GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
Query: 362 PLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PG---PPPPPPGPPGPGSSL 414
PL +P PP P PP PP G + PPP PG PP P P P PG+ +
Sbjct: 1178 PLPGVGIPPPPPLPGV-----GIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGI 1232
Query: 415 SSSPM---HGPPV 424
P+ GPP+
Sbjct: 1233 PPPPLLPVSGPPL 1245
Score = 63.9 bits (154), Expect = 3e-10
Identities = 64/203 (31%), Positives = 77/203 (37%), Gaps = 21/203 (10%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPP 310
P P+ ++ PQP P +PP P A PP A + L PPPP
Sbjct: 889 PTLPSTAI-PQP-PPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPP 946
Query: 311 QAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP----PPPPVIPSAQTAFVSPLQ-- 364
P + P P LP + P PP P PPPP +P A PL
Sbjct: 947 PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1006
Query: 365 -MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PGPP-PPPPGPPGPGSSLSSSPMHG 421
+P PP P + PP PP G + PPP PG PPPP PG G P+ G
Sbjct: 1007 GIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPG 1060
Query: 422 ----PPVAEAKRQEPAQPPISDA 440
PP P PP+ A
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGA 1083
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/182 (31%), Positives = 66/182 (36%), Gaps = 42/182 (23%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQ----PPP 306
P P + P P P +PP P AA PP + L P PPP
Sbjct: 924 PPLPGAGILPLPPLPG---AGIPPPPPLPGAAIPP--PPPLPGAGIPLPPPLPGAGIPPP 978
Query: 307 PP------PPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP------PPPPVIPS 354
PP PP P P P +P PPPP PPPP +P
Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-----------PPPPLPGAGIPPPPPLPG 1027
Query: 355 AQTAFVSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PGPP-PPPPGPPG 409
A PL +P PP P + PP PP G + PPP PG PPPP PG
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082
Query: 410 PG 411
G
Sbjct: 1083 AG 1084
Score = 61.6 bits (148), Expect = 2e-09
Identities = 67/212 (31%), Positives = 78/212 (36%), Gaps = 41/212 (19%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPP----- 305
P P + P P P A +PP P A PP A P PP
Sbjct: 935 PPLPGAGIPPPPPLPGAA---IPPPPPLPGAGI-PLPPPLPGA-----GIPPPPPLPGAG 985
Query: 306 -PPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPP-------PPPVIPSAQT 357
PPPPP G P+ A G+ P + PPPPP PPP +P A
Sbjct: 986 IPPPPPLPGAGIPPPPPLPGA--GIPPPPPLP--GAGIPPPPPLPGAGIPPPPPLPGAGI 1041
Query: 358 AFVSPLQ---MPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP-PGPP-PPPPGPPGPGS 412
PL +P PP P + PP PP G + PPP PG PPPP PG G
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
Query: 413 SLSSSPMHG----PPVAEAKRQEPAQPPISDA 440
P+ G PP P PP+ A
Sbjct: 1097 P-PPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127
Score = 40.0 bits (92), Expect = 0.005
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 40/191 (20%)
Query: 251 PATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPP----P 306
P P + P P P +PP P A PP + P P P
Sbjct: 1133 PPLPGAGIPPPPPLPRVG---IPPPPPLPGAGI----PPPPPLPGAGIPPPPPLPGVGIP 1185
Query: 307 PPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP 366
PPPP G P+ A G+ P + G PP P PP +P T P +P
Sbjct: 1186 PPPPLPGVGIPPPPPLPGA--GIPPPPPLP---GMGIPPAPAPP-LPPPGTGIPPPPLLP 1239
Query: 367 MQPP--FPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPV 424
+ P P SST P P G L PPP P G G G +
Sbjct: 1240 VSGPPLLPQVGSST---LPTPQVCGFL--------PPPLPSGLFGLGMNQD--------- 1279
Query: 425 AEAKRQEPAQP 435
+ R++P +P
Sbjct: 1280 -KGSRKQPIEP 1289
Score = 29.3 bits (64), Expect = 8.7
Identities = 16/51 (31%), Positives = 20/51 (39%)
Query: 372 PASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPPGPGSSLSSSPMHGP 422
P S ++ P PPS G L + P P P P S+ P GP
Sbjct: 280 PESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGP 330
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 71.6 bits (174), Expect = 2e-12
Identities = 70/247 (28%), Positives = 84/247 (34%), Gaps = 74/247 (29%)
Query: 225 YHGASSEGSLSPDTRSHASDVTDYSYPA---TPNHSLHP-------------QPVTPSYA 268
YHG G P H+ + +P T H HP QP P
Sbjct: 379 YHGMHGGGPGGPGGGPHS-----FPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMN 433
Query: 269 AGDVPP--HGPASQAAEHEYRPPSASARHMALNRPQQPPPP----PPPQAPEGSQASAPM 322
G PP HGP P + + + PPPP PPP P Q P
Sbjct: 434 QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP- 492
Query: 323 APADYGMLPAQIIEYYNPSGPPPP-------PPPPVIPSAQTAFVSPLQMPMQ------- 368
PSGP PP PPPP PS+ A +PL
Sbjct: 493 -----------------PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTS 535
Query: 369 ------PPFPASASSTHAAPPHPPSTG--LLVTAPP------PPGPPPPPPGPPGPGSSL 414
PP+ ++ A+P P G +V PP PPG PPPPP PP PGS+
Sbjct: 536 AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP-PPPPGSAG 594
Query: 415 SSSPMHG 421
P G
Sbjct: 595 MMIPPRG 601
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/212 (28%), Positives = 76/212 (35%), Gaps = 33/212 (15%)
Query: 243 SDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPP---SASARHMALN 299
+ V S PAT + P+P P+ + PP P S + + RPP S + +
Sbjct: 327 ASVGSTSGPATTPLASAPRPAAPA----NNPP--PPSLMSTTQSRPPWMNSGPSESRPYH 380
Query: 300 RPQQPPPPPPPQAPEGSQASAPMAPADYGMLPAQIIEYYNPSGPPPP---PPPPVIPSAQ 356
P P P P +G P Q +NP+GPPPP PPPP P Q
Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ----HNPNGPPPPWMQPPPP--PMNQ 434
Query: 357 TAFVSPLQMPMQPPFPASASSTHAAPP-----------HPPSTGLLVTAPPPPG--PPPP 403
P PP ST PP G++ PPPP PPPP
Sbjct: 435 GPHPPGHHGP--PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492
Query: 404 PPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQP 435
P GP P P PP + + P
Sbjct: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 16/65 (24%)
Query: 368 QPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPP--PPPPG--------PPGPGSSLSSS 417
+ P PAS ST P+T L +AP P P PPPP PP S S S
Sbjct: 322 EAPVPASVGSTSG-----PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSES 376
Query: 418 -PMHG 421
P HG
Sbjct: 377 RPYHG 381
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 71.2 bits (173), Expect = 2e-12
Identities = 69/246 (28%), Positives = 96/246 (39%), Gaps = 25/246 (10%)
Query: 235 SPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDV--PP--HGPASQAAEHEYRPPS 290
+P H ++ S P + N +L P P ++ PP H P Q PS
Sbjct: 387 APQAHKHPPHLSGPS-PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS 445
Query: 291 ASARHMALNRPQQPPPPPPPQAPEGSQASAPMAP-ADYGMLPAQIIEYYNPSGPPPPPPP 349
+ A+ L + Q PPPP P G AP P A + +P G PPP P
Sbjct: 446 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP----------GGPPPITP 495
Query: 350 PVIPSAQTAFVSPLQMPMQPPFPASASS-------THAAPPHPPSTGLLVTAPPPPGPPP 402
P PS T P QPP +A+S + P + P PP
Sbjct: 496 PTCPSTSTPPAGP-GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 554
Query: 403 PPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQRE 462
PPP P P ++ +P H A + + S AR+DL G +L K +E+
Sbjct: 555 PPPRSPSPEPTVVDTPSHASQSARFYKHLD-RGYNSCARTDLYFMPLAGSKLAKKREEAI 613
Query: 463 QEAKRE 468
++AKRE
Sbjct: 614 EKAKRE 619
Score = 57.4 bits (137), Expect = 3e-08
Identities = 100/446 (22%), Positives = 148/446 (33%), Gaps = 132/446 (29%)
Query: 109 QQVVSKNSIPNPVADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQD 168
+Q S + +P+ + S + P T D K + +K +K+ ++
Sbjct: 36 KQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSA----------KKVKEE 85
Query: 169 TEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVY-HG 227
K +RQ+E+ D T E + + + QE + E ++ S+SV G
Sbjct: 86 ASSPLKSNKRQREKVASD--TEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEG 143
Query: 228 ASSEGSLSPDTRSHA--------------------------------SDVTDYSYPATPN 255
+S + D RS + + VT A P
Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
Query: 256 HSLHPQPVTPSYAAGDVPPHG-PASQAAEHEYRPPSASARHMALNR-----PQQPPPPPP 309
P P P+ +A VPP G P + A ++ + P+A H + + PQ+PP P P
Sbjct: 204 TPQLPTP-GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 262
Query: 310 PQAPE-----------GSQASAPM---------------------------APADYGMLP 331
P P Q SAP P +G LP
Sbjct: 263 PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG-LP 321
Query: 332 AQIIEYYNPSGPPPPPPPP----VIPSAQTAFVS------------PLQMPMQPPFPAS- 374
Q + P G P P +P++Q+A S PL MP P P +
Sbjct: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381
Query: 375 -----ASSTHAAPPH---PPSTGLLVTAPPPPGPPP--------PPPGPPGP------GS 412
A H PPH P + PPPP P PP P P
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441
Query: 413 SLSSSPMHGPPVAEAKRQEPAQPPIS 438
L SSP P + +++ P PP S
Sbjct: 442 PLPSSPAQPPGLTQSQNLPP--PPAS 465
Score = 40.0 bits (92), Expect = 0.005
Identities = 53/267 (19%), Positives = 88/267 (32%), Gaps = 38/267 (14%)
Query: 170 EDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDNRLSQSVYHGAS 229
ED + +R G+ ++ RK + + ++++R R S S +S
Sbjct: 8 EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSS 67
Query: 230 SEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPASQAAEHEYRPP 289
++ +S + S P N + + + E R
Sbjct: 68 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDT----------------EEADRTS 111
Query: 290 SASARHMALNRPQQPPPPPPPQAPEGS-QASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
S + ++RP P EG ++S + D G + I+ N S P P
Sbjct: 112 SKKTKTQEISRPNSPS--------EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS 163
Query: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
P S + + QPP + + AP + PPG P P P
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP-----------SSAPPGTPQLPT--P 210
Query: 409 GPGSSLSSSPMHGPPVAEAKRQEPAQP 435
GP S ++ P G P A +P P
Sbjct: 211 GPTPSATAVPPQGSPTASQAPNQPQAP 237
Score = 35.8 bits (81), Expect = 0.093
Identities = 38/154 (24%), Positives = 58/154 (37%), Gaps = 22/154 (14%)
Query: 156 YFFDLWKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELR 215
YF L K+ + E+ ++ +R+ EQK + RE K+ K R R +E ++E
Sbjct: 596 YFMPLAGSKLAKKREEAIEKAKREAEQKAREERERE-KEKEKERERERE-----REREAE 649
Query: 216 PDNRLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPH 275
+ S S + G S+ LS P S P P T + + P
Sbjct: 650 RAAKASSSAHEGRLSDPQLSG--------------PGHMRPSFEPPPTTIAAVPPYIGPD 695
Query: 276 GPASQAAEHEYRP--PSASARHMALNRPQQPPPP 307
PA + RP S + R+ P P P
Sbjct: 696 TPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP 729
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,954,628
Number of Sequences: 37866
Number of extensions: 2284231
Number of successful extensions: 76551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1211
Number of HSP's successfully gapped in prelim test: 1991
Number of HSP's that attempted gapping in prelim test: 17452
Number of HSP's gapped (non-prelim): 22406
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.