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Search of human proteins with 66912172
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
(186 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66912172 hairy and enhancer of split 3 [Homo sapiens] 382 e-106
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens] 79 2e-15
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens] 79 2e-15
gi|5031763 hairy and enhancer of split 1 [Homo sapiens] 78 5e-15
gi|58219048 hairy and enhancer of split 5 [Homo sapiens] 67 9e-12
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens] 66 2e-11
gi|145207994 hairy and enhancer of split 7 [Homo sapiens] 60 8e-10
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho... 50 1e-06
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens] 48 6e-06
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i... 47 9e-06
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens] 47 9e-06
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i... 45 4e-05
gi|13540521 basic helix-loop-helix domain containing, class B, 3... 43 1e-04
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens] 42 2e-04
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 41 7e-04
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 40 9e-04
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 40 9e-04
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 40 9e-04
gi|33946327 nucleoporin 214kDa [Homo sapiens] 40 9e-04
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ... 40 9e-04
gi|239751469 PREDICTED: hypothetical protein [Homo sapiens] 40 0.001
gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 40 0.001
gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 40 0.001
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 40 0.002
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 39 0.003
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 39 0.003
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 39 0.003
gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapi... 39 0.003
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 39 0.003
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 39 0.003
>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
Length = 186
Score = 382 bits (980), Expect = e-106
Identities = 186/186 (100%), Positives = 186/186 (100%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP
Sbjct: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
Query: 61 RGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPC 120
RGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPC
Sbjct: 61 RGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPC 120
Query: 121 TPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPWGS 180
TPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPWGS
Sbjct: 121 TPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPWGS 180
Query: 181 PGDDLN 186
PGDDLN
Sbjct: 181 PGDDLN 186
>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
Length = 247
Score = 79.3 bits (194), Expect = 2e-15
Identities = 71/189 (37%), Positives = 95/189 (50%), Gaps = 22/189 (11%)
Query: 1 MEKKRRARINVSLEQLKSL-LEKHYSHQIRKRKLEKADILELSVKYMRSLQ----NSLQG 55
MEK+RRARIN SL QLK+L L+ R KLEKADILE++V+++RSL+ +
Sbjct: 68 MEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALS 127
Query: 56 LWPVPRGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPA 115
P G + +GF CL V++ L + V + +R L+ AA + G + PA
Sbjct: 128 ADPAVLG-KYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAA--CLRQLGPSRR-PA 183
Query: 116 LFRPCTPAVWAPAPA--AGGPRSP----PPLLLLPESLPGSSASVPPPQPASSRCAESPG 169
P PA APAP AG P P P LL P LPG + ++P A + P
Sbjct: 184 SLSPAAPAE-APAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGP- 241
Query: 170 LGLRVWRPW 178
WRPW
Sbjct: 242 -----WRPW 245
>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
Length = 221
Score = 79.3 bits (194), Expect = 2e-15
Identities = 71/189 (37%), Positives = 95/189 (50%), Gaps = 22/189 (11%)
Query: 1 MEKKRRARINVSLEQLKSL-LEKHYSHQIRKRKLEKADILELSVKYMRSLQ----NSLQG 55
MEK+RRARIN SL QLK+L L+ R KLEKADILE++V+++RSL+ +
Sbjct: 42 MEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALS 101
Query: 56 LWPVPRGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPA 115
P G + +GF CL V++ L + V + +R L+ AA + G + PA
Sbjct: 102 ADPAVLG-KYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAA--CLRQLGPSRR-PA 157
Query: 116 LFRPCTPAVWAPAPA--AGGPRSP----PPLLLLPESLPGSSASVPPPQPASSRCAESPG 169
P PA APAP AG P P P LL P LPG + ++P A + P
Sbjct: 158 SLSPAAPAE-APAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGP- 215
Query: 170 LGLRVWRPW 178
WRPW
Sbjct: 216 -----WRPW 219
>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
Length = 280
Score = 77.8 bits (190), Expect = 5e-15
Identities = 68/185 (36%), Positives = 95/185 (51%), Gaps = 20/185 (10%)
Query: 1 MEKKRRARINVSLEQLKSL-LEKHYSHQIRKRKLEKADILELSVKYMRSLQNS--LQGLW 57
MEK+RRARIN SL QLK+L L+ R KLEKADILE++VK++R+LQ + L
Sbjct: 42 MEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALS 101
Query: 58 PVPRG-AEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGL--GQEAP 114
P + +GF C+ V++ L + V + +R L+ A T +A GQ P
Sbjct: 102 TDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHP 161
Query: 115 ALFRPCTPAVWAPAPAAGGPR----SPPPLLLLPESLPGSSASVPPPQPASSRCAESPGL 170
AL P P P GGP+ +PPP L+ +PG +A PPP A + G
Sbjct: 162 ALQAPP-----PPPPGPGGPQHAPFAPPPPLV---PIPGGAA--PPPGGAPCKLGSQAGE 211
Query: 171 GLRVW 175
+V+
Sbjct: 212 AAKVF 216
>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
Length = 166
Score = 67.0 bits (162), Expect = 9e-12
Identities = 56/178 (31%), Positives = 77/178 (43%), Gaps = 35/178 (19%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
+EK RR RIN S+EQLK LLE+ ++ KLEKADILE++V Y++ + + P
Sbjct: 24 VEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFVAAAGPKS 83
Query: 61 RGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPC 120
+ G+ CL Q L +A+ + M Q PA P
Sbjct: 84 LHQDYSEGYSWCLQEAVQF--------------LTLHAASDTQMKLLYHFQRPPA--APA 127
Query: 121 TPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPW 178
PA AP A +PPP L S ++A+ QPA +WRPW
Sbjct: 128 APAKEPKAPGA----APPPAL----SAKATAAAAAAHQPACG-----------LWRPW 166
>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
Length = 173
Score = 66.2 bits (160), Expect = 2e-11
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 39/185 (21%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRK-RKLEKADILELSVKYMRSLQNSLQGLWPV 59
+EK+RRARIN SL QLK L+ + KLEKAD+LE++V++++ L S WP
Sbjct: 21 LEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS---SWPT 77
Query: 60 PRGAEQPS---GFRSCLPGVSQLLRRGDEVGSGLRCPLVP---ESAAGSTMDSAGLGQEA 113
S G+ +C+ ++++L + + L+ AA +T+D G +
Sbjct: 78 AAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSS 137
Query: 114 PALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLR 173
P+ APAPA+ +P P AS P P P S C PGL
Sbjct: 138 -------GPSAPAPAPAS----APEP------------ASAPVPSPPSPPC--GPGL--- 169
Query: 174 VWRPW 178
WRPW
Sbjct: 170 -WRPW 173
>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
Length = 225
Score = 60.5 bits (145), Expect = 8e-10
Identities = 69/220 (31%), Positives = 90/220 (40%), Gaps = 57/220 (25%)
Query: 1 MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPV 59
+EK+RR RIN SLE+L+ LL E+ +R KLEKA+ILE +V Y+R + S V
Sbjct: 20 VEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLR--ERSRVEPPGV 77
Query: 60 PRGAEQP---------SGFRSCLPGVSQLLRRGD-----EVGSGLRCPLVPESAAGSTMD 105
PR Q SGFR CL ++ ++ S L L P+ +D
Sbjct: 78 PRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAARAQLFSALHGYLRPKPPRPKPVD 137
Query: 106 ------SAGLGQEAPAL------------FRPCTPAVWAP---APAAGGPRSPPPLL-LL 143
L APAL P W+P +P AG +P PL LL
Sbjct: 138 PRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPRAGDSGAPAPLTGLL 197
Query: 144 PESLP-----GSSASVPPPQPASSRCAESPGLGLRVWRPW 178
P P G+ + PP PA WRPW
Sbjct: 198 PPPPPPHRQDGAPKAPLPPPPA-------------FWRPW 224
>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
sapiens]
Length = 337
Score = 49.7 bits (117), Expect = 1e-06
Identities = 54/169 (31%), Positives = 79/169 (46%), Gaps = 17/169 (10%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQ-NSLQGLWPV 59
+EK+RR RIN SL +L+ L+ + Q KLEKA+IL+++V +++ LQ +G +
Sbjct: 56 IEKRRRDRINNSLSELRRLVPTAFEKQ-GSAKLEKAEILQMTVDHLKMLQATGGKGYFDA 114
Query: 60 PRGAE--QPSGFRSCLPGVSQLLR--RGDEVGSGLRCPLVPE-SAAGSTMDSAGLGQEAP 114
A GFR CL V++ L G + LR LV S + ++A +
Sbjct: 115 HALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREAAAMTSSMA 174
Query: 115 ALFRPCTPAVWAPA----PAAGGPRSPPPLLLLPESLP---GSSASVPP 156
P P WA A PAA P L ES P +++ VPP
Sbjct: 175 HHHHPLHPHHWAAAFHHLPAA---LLQPNGLHASESTPCRLSTTSEVPP 220
>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
Length = 222
Score = 47.8 bits (112), Expect = 6e-06
Identities = 57/202 (28%), Positives = 83/202 (41%), Gaps = 36/202 (17%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
+EKKRRARIN SL++L+ LL + KLE A++LEL+V R +Q L+G
Sbjct: 33 VEKKRRARINESLQELRLLLAG------AEAKLENAEVLELTV---RRVQGVLRGR---A 80
Query: 61 RGAEQ---------PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQ 111
R EQ +G+ C+ V + + + + L+ + Q
Sbjct: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
Query: 112 E--APALFRPCTPAVWAPAPAAGGPRSPPP------------LLLLPES-LPGSSASVPP 156
+ AL P + PA G P SP P L PE+ L + A P
Sbjct: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
Query: 157 PQPASSRCAESPGLGLRVWRPW 178
PA+ + + VWRPW
Sbjct: 201 LVPAALGSLTTAQIARSVWRPW 222
>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
isoform b [Homo sapiens]
Length = 308
Score = 47.0 bits (110), Expect = 9e-06
Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKR---KLEKADILELSVKYMRSLQNS-LQGL 56
+EK+RR RIN SL +L+ L+ + Q+ ++ KLEKA+IL+++V +++ L + +G
Sbjct: 57 IEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLHTAGGKGY 116
Query: 57 WPVPRGA--EQPSGFRSCLPGVSQLLR--RGDEVGSGLRCPLVPESAAGSTMDSAGLGQE 112
+ A + GFR CL V++ L G + LR LV ++ A G
Sbjct: 117 FDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAH 176
Query: 113 APALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPP 157
A P V+ P P LLLP++ G++ + P
Sbjct: 177 AGLGHIP-WGTVFGHHPHIAHP------LLLPQNGHGNAGTTASP 214
>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
Length = 224
Score = 47.0 bits (110), Expect = 9e-06
Identities = 57/202 (28%), Positives = 84/202 (41%), Gaps = 34/202 (16%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
+EKKRRARIN SL++L+ LL + + KLE A++LEL+V R +Q L+G
Sbjct: 33 VEKKRRARINESLQELRLLL----AGAEVQAKLENAEVLELTV---RRVQGVLRGR---A 82
Query: 61 RGAEQ---------PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQ 111
R EQ +G+ C+ V + + + + L+ + Q
Sbjct: 83 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 142
Query: 112 E--APALFRPCTPAVWAPAPAAGGPRSPPP------------LLLLPES-LPGSSASVPP 156
+ AL P + PA G P SP P L PE+ L + A P
Sbjct: 143 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 202
Query: 157 PQPASSRCAESPGLGLRVWRPW 178
PA+ + + VWRPW
Sbjct: 203 LVPAALGSLTTAQIARSVWRPW 224
>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
isoform a [Homo sapiens]
Length = 304
Score = 45.1 bits (105), Expect = 4e-05
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 13/162 (8%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNS-LQGLWPV 59
+EK+RR RIN SL +L+ L+ + Q KLEKA+IL+++V +++ L + +G +
Sbjct: 57 IEKRRRDRINNSLSELRRLVPSAFEKQ-GSAKLEKAEILQMTVDHLKMLHTAGGKGYFDA 115
Query: 60 PRGA--EQPSGFRSCLPGVSQLLR--RGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPA 115
A + GFR CL V++ L G + LR LV ++ A G A
Sbjct: 116 HALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGL 175
Query: 116 LFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPP 157
P V+ P P LLLP++ G++ + P
Sbjct: 176 GHIP-WGTVFGHHPHIAHP------LLLPQNGHGNAGTTASP 210
>gi|13540521 basic helix-loop-helix domain containing, class B, 3
[Homo sapiens]
Length = 482
Score = 43.1 bits (100), Expect = 1e-04
Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 17/98 (17%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSL-------QNSL 53
+EKKRR RIN + QLK LL +H LEKA +LEL++K++++L +
Sbjct: 52 IEKKRRDRINECIAQLKDLLPEHLK-LTTLGHLEKAVVLELTLKHLKALTALTEQQHQKI 110
Query: 54 QGLWPVPRGAEQP---------SGFRSCLPGVSQLLRR 82
L R + P SGF++C V Q L R
Sbjct: 111 IALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSR 148
>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
Length = 412
Score = 42.4 bits (98), Expect = 2e-04
Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQN 51
+EKKRR RIN + QLK LL +H LEKA +LEL++K++++L N
Sbjct: 60 IEKKRRDRINECIAQLKDLLPEHLK-LTTLGHLEKAVVLELTLKHVKALTN 109
>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
Length = 2608
Score = 40.8 bits (94), Expect = 7e-04
Identities = 28/67 (41%), Positives = 34/67 (50%), Gaps = 10/67 (14%)
Query: 114 PALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRC------AES 167
P P P AP+PAAG P PP P+ P +S+ PPP+P S+ C A S
Sbjct: 970 PVALTPTAPG--APSPAAG-PTKLPPCCHPPDPKPPASSPTPPPRP-SAPCTLNVCPASS 1025
Query: 168 PGLGLRV 174
PG G RV
Sbjct: 1026 PGPGSRV 1032
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 40.4 bits (93), Expect = 9e-04
Identities = 33/100 (33%), Positives = 40/100 (40%), Gaps = 22/100 (22%)
Query: 83 GDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPPLLL 142
G G+G R L P T+D++ L P P AG SPPPL L
Sbjct: 255 GVGAGAGARGKLSPRKGKSKTLDNSDL----------------HPGPPAG---SPPPLTL 295
Query: 143 LPESLPG---SSASVPPPQPASSRCAESPGLGLRVWRPWG 179
P P ++AS PP PA E P GL+ R G
Sbjct: 296 PPTPSPATAVTAASAQPPGPAPPITLEPPAPGLKRGREGG 335
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 40.4 bits (93), Expect = 9e-04
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 11/129 (8%)
Query: 38 ILELSVKYMRSLQNSLQGLWPVPRGAEQPSGFRSCLPGV--SQLLRRGDEVG---SGLRC 92
++ LS +++ L + + P P G+E P+ L + LLRRG E+G R
Sbjct: 17 LILLSCPWIQGLPLKEEEILPEP-GSETPTVASEALAELLHGALLRRGPEMGYLPGSDRD 75
Query: 93 PLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSA 152
P + AG T+ L + P T AV GP +P LL P PG++A
Sbjct: 76 PTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPE--LLTPP--PGTTA 131
Query: 153 SVPPPQPAS 161
PPP PAS
Sbjct: 132 P-PPPSPAS 139
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 40.4 bits (93), Expect = 9e-04
Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 11/129 (8%)
Query: 38 ILELSVKYMRSLQNSLQGLWPVPRGAEQPSGFRSCLPGV--SQLLRRGDEVG---SGLRC 92
++ LS +++ L + + P P G+E P+ L + LLRRG E+G R
Sbjct: 17 LILLSCPWIQGLPLKEEEILPEP-GSETPTVASEALAELLHGALLRRGPEMGYLPGSDRD 75
Query: 93 PLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSA 152
P + AG T+ L + P T AV GP +P LL P PG++A
Sbjct: 76 PTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPE--LLTPP--PGTTA 131
Query: 153 SVPPPQPAS 161
PPP PAS
Sbjct: 132 P-PPPSPAS 139
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 40.4 bits (93), Expect = 9e-04
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 10/101 (9%)
Query: 88 SGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRS-PPPLLLLPES 146
S ++ L + A +T Q AP P +P A PAA GP S P PL P S
Sbjct: 581 SAVKVNLSEKFTAAATSTPVSSSQSAP----PMSPFSSASKPAASGPLSHPTPLSAPPSS 636
Query: 147 LPGSSASVPPPQPASSRCAESPGLGL-----RVWRPWGSPG 182
+P S+ +P P S++ + SP + R+ P PG
Sbjct: 637 VPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPG 677
>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
Length = 328
Score = 40.4 bits (93), Expect = 9e-04
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 4/83 (4%)
Query: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQ-NSLQGLWPV 59
+EK+RR RIN SL +L+ L+ + Q KLEKA++L+++V +++ L G +
Sbjct: 51 IEKRRRDRINSSLSELRRLVPTAFEKQ-GSSKLEKAEVLQMTVDHLKMLHATGGTGFFDA 109
Query: 60 PRGAE--QPSGFRSCLPGVSQLL 80
A + GFR CL V + L
Sbjct: 110 RALAVDFRSIGFRECLTEVIRYL 132
Score = 32.0 bits (71), Expect = 0.32
Identities = 35/110 (31%), Positives = 43/110 (39%), Gaps = 20/110 (18%)
Query: 80 LRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPP 139
LRR + R ++P A ST + A L RP TP AP+ A P
Sbjct: 222 LRRATGIILPARRNVLPSRGASST-------RRARPLERPATPVPVAPSSRAARSSHIAP 274
Query: 140 LLLLPESLP----GSSASVPPPQPASSRCAESPG-----LGLRVWRPWGS 180
LL P GS+A V P P SS SPG G ++ W S
Sbjct: 275 LLQSSSPTPPGPTGSAAYVAVPTPNSS----SPGPAGRPAGAMLYHSWVS 320
>gi|239751469 PREDICTED: hypothetical protein [Homo sapiens]
Length = 278
Score = 40.0 bits (92), Expect = 0.001
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 122 PAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPWGSP 181
P+ WA + PR+P P + S+PGSS + P A C P GL+ PW SP
Sbjct: 19 PSGWAMGHPSCSPRTPVPPM---SSIPGSSGCLGVPFSAPEGCVPRPHAGLQATCPWISP 75
>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
Length = 976
Score = 40.0 bits (92), Expect = 0.001
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 19/166 (11%)
Query: 10 NVSLEQLKSLLEKHYSHQIRKR-KLEKADILELSVKYMRSLQNSLQGLWPVPRGAEQPSG 68
NV+LE+++ L E+H SH K LE +++ ++ + LQ + L + E S
Sbjct: 341 NVALEKVEEL-EEHVSHLTEKLLDLENENMMRVAELEKQLLQREKE-LESIKETYENTSH 398
Query: 69 FRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPA----V 124
L +L++ +E RC L P ++DS L + PA P +
Sbjct: 399 QVHTL---RRLIKEKEEAFQR-RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDL 454
Query: 125 WAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGL 170
APAP PP +LP P + PPP P +C +P L
Sbjct: 455 LAPAP--------PPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPL 492
>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
Length = 1027
Score = 40.0 bits (92), Expect = 0.001
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 19/166 (11%)
Query: 10 NVSLEQLKSLLEKHYSHQIRKR-KLEKADILELSVKYMRSLQNSLQGLWPVPRGAEQPSG 68
NV+LE+++ L E+H SH K LE +++ ++ + LQ + L + E S
Sbjct: 392 NVALEKVEEL-EEHVSHLTEKLLDLENENMMRVAELEKQLLQREKE-LESIKETYENTSH 449
Query: 69 FRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPA----V 124
L +L++ +E RC L P ++DS L + PA P +
Sbjct: 450 QVHTL---RRLIKEKEEAFQR-RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDL 505
Query: 125 WAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGL 170
APAP PP +LP P + PPP P +C +P L
Sbjct: 506 LAPAP--------PPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPL 543
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 39.7 bits (91), Expect = 0.002
Identities = 41/139 (29%), Positives = 48/139 (34%), Gaps = 25/139 (17%)
Query: 58 PVPRGAEQPSGFRSCLPGVSQLLRRGDEVGS-----GLRCPLVPESAAGSTMDSAGLGQ- 111
P+P G SCLP L RGD V L CP PE + + L
Sbjct: 695 PLPCPLCSREGACSCLP-----LERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADL 749
Query: 112 -------EAPALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRC 164
P P A P G P +PPP P + +AS PP +
Sbjct: 750 PMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVA--- 806
Query: 165 AESPGLGLRVWRPWGSPGD 183
SPG GL P PGD
Sbjct: 807 --SPGSGLS--SPGPKPGD 821
Score = 29.6 bits (65), Expect = 1.6
Identities = 21/68 (30%), Positives = 26/68 (38%), Gaps = 8/68 (11%)
Query: 121 TPAVWAPAPAAGGP-------RSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLR 173
TP W PAP G P R+P P ++ S G + P PA PG R
Sbjct: 1062 TPESWGPAPTIGEPAPETSLERAPAPSAVV-SSRNGGETAPGPLGPAPKNGTLEPGTERR 1120
Query: 174 VWRPWGSP 181
G+P
Sbjct: 1121 APETGGAP 1128
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 38.9 bits (89), Expect = 0.003
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 87 GSGLRCPLV-------PESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPP 139
GSG P V P S A T S GQ P L P P+ P P +PPP
Sbjct: 729 GSGFPAPTVESTPDVCPSSPALQT-PSLSSGQLPPLLI-PTDPSSPPPCPPVLTVATPPP 786
Query: 140 LLLLPESLPGSSASVPP---PQPASSRCAESPGLGLRVWRPWGSP 181
LL LP S+S P P P S+ A+SP L + P SP
Sbjct: 787 PLLPTVPLPAPSSSASPHPCPSPLSNATAQSP---LPILSPTVSP 828
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 38.9 bits (89), Expect = 0.003
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 87 GSGLRCPLV-------PESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPP 139
GSG P V P S A T S GQ P L P P+ P P +PPP
Sbjct: 930 GSGFPAPTVESTPDVCPSSPALQT-PSLSSGQLPPLLI-PTDPSSPPPCPPVLTVATPPP 987
Query: 140 LLLLPESLPGSSASVPP---PQPASSRCAESPGLGLRVWRPWGSP 181
LL LP S+S P P P S+ A+SP L + P SP
Sbjct: 988 PLLPTVPLPAPSSSASPHPCPSPLSNATAQSP---LPILSPTVSP 1029
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 38.9 bits (89), Expect = 0.003
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 87 GSGLRCPLV-------PESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPP 139
GSG P V P S A T S GQ P L P P+ P P +PPP
Sbjct: 930 GSGFPAPTVESTPDVCPSSPALQT-PSLSSGQLPPLLI-PTDPSSPPPCPPVLTVATPPP 987
Query: 140 LLLLPESLPGSSASVPP---PQPASSRCAESPGLGLRVWRPWGSP 181
LL LP S+S P P P S+ A+SP L + P SP
Sbjct: 988 PLLPTVPLPAPSSSASPHPCPSPLSNATAQSP---LPILSPTVSP 1029
>gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo
sapiens]
Length = 520
Score = 38.5 bits (88), Expect = 0.003
Identities = 37/110 (33%), Positives = 43/110 (39%), Gaps = 18/110 (16%)
Query: 77 SQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPCTPAVWAPAPAAGGPRS 136
S L G G + P+VP A + S G Q AP L P AP + P
Sbjct: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQL--PLN-----AAPPSSVPPV 336
Query: 137 PPPLLLLPESLPGSSA------SVPPPQPASSRCAESPGLGLR-VWRPWG 179
PP L P + P + A S PPP R A LG R W PWG
Sbjct: 337 PPSEALPPPACPSAPAPRRSIISRPPPWGWRLRGA----LGRRGQWPPWG 382
>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
Length = 1062
Score = 38.5 bits (88), Expect = 0.003
Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 18/169 (10%)
Query: 6 RARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVPRGAEQ 65
R RI + + ++ EKH + Q + E + KY+ Q +G PRG +
Sbjct: 310 RLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREG----PRGGVR 365
Query: 66 PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLG----QEAPALFRPCT 121
S R PG+S L RG + S+ G ++ G+ + +P RP
Sbjct: 366 CSSSRGGRPGLSSLPPRGPHH--------LDNSSPGPGSEARGINGGPSRMSPKAQRPLR 417
Query: 122 PA--VWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESP 168
A + +P+ G S PP + P S P P S+ C E P
Sbjct: 418 GAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPP 466
>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
Length = 1044
Score = 38.5 bits (88), Expect = 0.003
Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 18/169 (10%)
Query: 6 RARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVPRGAEQ 65
R RI + + ++ EKH + Q + E + KY+ Q +G PRG +
Sbjct: 310 RLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREG----PRGGVR 365
Query: 66 PSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLG----QEAPALFRPCT 121
S R PG+S L RG + S+ G ++ G+ + +P RP
Sbjct: 366 CSSSRGGRPGLSSLPPRGPHH--------LDNSSPGPGSEARGINGGPSRMSPKAQRPLR 417
Query: 122 PA--VWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESP 168
A + +P+ G S PP + P S P P S+ C E P
Sbjct: 418 GAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPP 466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,754,971
Number of Sequences: 37866
Number of extensions: 652048
Number of successful extensions: 6118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 635
Number of HSP's that attempted gapping in prelim test: 4432
Number of HSP's gapped (non-prelim): 2037
length of query: 186
length of database: 18,247,518
effective HSP length: 96
effective length of query: 90
effective length of database: 14,612,382
effective search space: 1315114380
effective search space used: 1315114380
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.