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Search of human proteins with 64085377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 1184 0.0
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 1077 0.0
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 777 0.0
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 749 0.0
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 433 e-121
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 95 2e-19
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 86 7e-17
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 79 1e-14
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 79 1e-14
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 79 1e-14
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 78 3e-14
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 77 5e-14
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 77 6e-14
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 77 6e-14
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 74 3e-13
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 74 4e-13
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 74 4e-13
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 74 4e-13
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 73 9e-13
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 73 9e-13
gi|17402900 far upstream element-binding protein [Homo sapiens] 71 2e-12
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 69 9e-12
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 69 2e-11
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 61 3e-09
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 61 3e-09
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 61 3e-09
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 58 2e-08
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 58 2e-08
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 53 7e-07
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 53 7e-07
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 1184 bits (3064), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG
Sbjct: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
Query: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET
Sbjct: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
Query: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG
Sbjct: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
Query: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK
Sbjct: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
Query: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI
Sbjct: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
Query: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQA 360
EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQA
Sbjct: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQA 360
Query: 361 NLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
NLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH
Sbjct: 361 NLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
Query: 421 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 480
HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG
Sbjct: 421 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 480
Query: 481 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 540
PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS
Sbjct: 481 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 540
Query: 541 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK
Sbjct: 541 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 1077 bits (2784), Expect = 0.0
Identities = 556/599 (92%), Positives = 556/599 (92%), Gaps = 43/599 (7%)
Query: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG
Sbjct: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
Query: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET
Sbjct: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
Query: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG
Sbjct: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
Query: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK
Sbjct: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
Query: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI
Sbjct: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
Query: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQA 360
EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN
Sbjct: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN--- 357
Query: 361 NLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
THSGYFSSLYPHHQFGPFPH
Sbjct: 358 ----------------------------------------THSGYFSSLYPHHQFGPFPH 377
Query: 421 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 480
HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG
Sbjct: 378 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 437
Query: 481 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 540
PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS
Sbjct: 438 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 497
Query: 541 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK
Sbjct: 498 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 777 bits (2006), Expect = 0.0
Identities = 396/603 (65%), Positives = 476/603 (78%), Gaps = 31/603 (5%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
VVNVTY+ RE+ + A+ KL+GHQ EN++ K+SYIPDE+++ P+ +RG SR Q
Sbjct: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQG--PENGRRGGFGSRGQPR 178
Query: 182 -----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSG 236
A G ++ +Q+D PLR+LVPTQ+VGAIIGKEG TI+NITKQTQS++D+HRKEN+G
Sbjct: 179 QGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAG 238
Query: 237 AAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRN 296
AAEK +++H+TPEG S AC+MILEIM KEA +TK A+E+PLKILAHN VGRLIGKEGRN
Sbjct: 239 AAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
Query: 297 LKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAV 356
LKK+E +T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A+
Sbjct: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
Query: 357 NQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFG 416
+ Q++LIPGLNL+A+G+F S + PP P AAPY F
Sbjct: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPP--PSSVTGAAPYSSFM---------------- 400
Query: 417 PFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 476
PEQE+V +FIP QAVGAIIGKKG HIKQL+RFA ASIKIAP E PD RMV
Sbjct: 401 ------QAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMV 454
Query: 477 IITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQ 536
IITGPPEAQFKAQGRI+GKLKEENFF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQ
Sbjct: 455 IITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQ 514
Query: 537 NLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQ 596
NLT+AEV+VPRDQTPDEN++VIV+IIGHF+ASQ AQRKIR+I+ QVKQQ QK A
Sbjct: 515 NLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQA 574
Query: 597 RSK 599
R K
Sbjct: 575 RRK 577
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 749 bits (1934), Expect = 0.0
Identities = 386/591 (65%), Positives = 466/591 (78%), Gaps = 29/591 (4%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNLS DL +F D K+P++G L+K+GYAFVD PD++WA++AIE LSGK
Sbjct: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
+ELHGK +EV++SV K+ R RK+QIRNIPPHLQWEVLD LL QYG VE+ EQVNTD+ETA
Sbjct: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQ----RAQRGDHSSR 177
VVNVTY+++++A+ A++KL+G Q EN++ K++YIPDE + +P Q R G S
Sbjct: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
Query: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
QG +PG S+ + D PLR+LVPTQFVGAIIGKEG TI+NITKQTQS++D+HRKEN+GA
Sbjct: 181 RQG-SPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA 239
Query: 238 AEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
AEK +TI +TPEGTS AC+ ILEIM KEA + K EEIPLKILAHN VGRLIGKEGRNL
Sbjct: 240 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNL 299
Query: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
KKIE +T TKITIS LQ+L++YNPERTITVKG VE CA AE EIMKK+RE++END+ ++N
Sbjct: 300 KKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMN 359
Query: 358 QQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGP 417
QA+LIPGLNL+ALG+F PP G PP SG S++ P P
Sbjct: 360 LQAHLIPGLNLNALGLF--------PPTS--GMPPPT--------SGPPSAMTP-----P 396
Query: 418 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 477
+P E E V+LFIP +VGAIIGK+G HIKQL+RFAGASIKIAPAE PD RMVI
Sbjct: 397 YPQFEQ-SETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVI 455
Query: 478 ITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQN 537
ITGPPEAQFKAQGRI+GK+KEENF +PKEEVKLEAHIRVPS AGRVIGKGGKTVNELQN
Sbjct: 456 ITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQN 515
Query: 538 LTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQK 588
L+SAEV+VPRDQTPDEN++V+V+I GHF+A Q AQRKI+EI+ QVKQ +Q+
Sbjct: 516 LSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 433 bits (1113), Expect = e-121
Identities = 226/357 (63%), Positives = 267/357 (74%), Gaps = 24/357 (6%)
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
T+ + +E+ ++ + ++T+ A+E+PLKILAHN VGRLIGKEGRNLKK+E
Sbjct: 106 TVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQ 165
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANL 362
+T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A++ Q++L
Sbjct: 166 DTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHL 225
Query: 363 IPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHH 422
IPGLNL+A+G+F S + PP P AAPY F
Sbjct: 226 IPGLNLAAVGLFPASSSAVPPP--PSSVTGAAPYSSFM---------------------- 261
Query: 423 SYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPP 482
PEQE+V +FIP QAVGAIIGKKG HIKQL+RFA ASIKIAP E PD RMVIITGPP
Sbjct: 262 QAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPP 321
Query: 483 EAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAE 542
EAQFKAQGRI+GKLKEENFF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AE
Sbjct: 322 EAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381
Query: 543 VIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
V+VPRDQTPDEN++VIV+IIGHF+ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 382 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
Score = 216 bits (550), Expect = 5e-56
Identities = 169/513 (32%), Positives = 245/513 (47%), Gaps = 121/513 (23%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
VVNVTY S+REQ
Sbjct: 121 VVNVTY-----------------------------------------------SNREQ-- 131
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA--AE 239
T QA ++ PL+IL FVG +IGKEG +K + + T++++ I ++ E
Sbjct: 132 ----TRQADEV--PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPE 185
Query: 240 KPVTIHATPEGTSEACRMILEIMQK--EADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
+ +T+ E CR EIM+K EA E +A L LI G NL
Sbjct: 186 RTITVKGAIE---NCCRAEQEIMKKVREAYENDVAA---------MSLQSHLI--PGLNL 231
Query: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
+ + ++ P ++T + +A E +M+ V
Sbjct: 232 --------AAVGLFPASSSAVPPPPSSVTGAAPYSS-----------FMQAPEQEMVQVF 272
Query: 358 QQANLI------PGLNLSALGIFSTGLSVLSPPAGPRG--------APPAAPYHPFTTHS 403
A + G ++ L F++ ++PP P PP A F
Sbjct: 273 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEA---QFKAQG 329
Query: 404 GYFSSLYPHHQFGPFPHHHSYPEQEI---VNLFIPTQAVGAIIGKKGAHIKQLARFAGAS 460
+ L + FG P++E+ ++ +P A G +IGK G + +L A
Sbjct: 330 RIYGKLKEENFFG--------PKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381
Query: 461 IKIAPAEGPDVSERMVI-ITGPPEAQFKAQGRI 492
+ + + PD ++++++ I G A AQ +I
Sbjct: 382 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKI 414
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 94.7 bits (234), Expect = 2e-19
Identities = 98/355 (27%), Positives = 161/355 (45%), Gaps = 35/355 (9%)
Query: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
Query: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 268 ETKLAEE-IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
Query: 327 VKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAG 386
+ GT +A +I + EA+ Q IP +L+ L L++ P
Sbjct: 180 ISGTPDAIIQCVKQICVVMLEAY------TIQGQYAIPHPDLTKLH----QLAMQQTPFP 229
Query: 387 PRGAP-PAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445
P G PA P HS S + G + P L IP +G IIG+
Sbjct: 230 PLGQTNPAFPGEKLPLHS----SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGR 285
Query: 446 KGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
+G I ++ + +GA IKIA A EG SER + ITG P AQ I +L E
Sbjct: 286 QGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISLAQYLINARLTSE 338
Score = 76.3 bits (186), Expect = 8e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 545 VPRDQTPDENEEVI 558
V D P+ E +
Sbjct: 165 VAGDMLPNSTERAV 178
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 86.3 bits (212), Expect = 7e-17
Identities = 98/373 (26%), Positives = 160/373 (42%), Gaps = 45/373 (12%)
Query: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
Query: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
Query: 327 VKGTVEACASAEIEIMKKLREA-------------FENDMLAVNQQANLIPGLNLSALGI 373
+ GT +A +I + E+ ++ QA I G
Sbjct: 180 ISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPD 239
Query: 374 FSTGLSVLS------PPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQ 427
T L L+ PP G PA P H SS + G + P
Sbjct: 240 QLTKLHQLAMQQTPFPPLGQTN--PAFPGEKLPLH----SSEEAQNLMGQSSGLDASPPA 293
Query: 428 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQF 486
L IP +G IIG++G I ++ + +GA IKIA A EG SER + ITG P
Sbjct: 294 STHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANIS 351
Query: 487 KAQGRIFGKLKEE 499
AQ I +L E
Sbjct: 352 LAQYLINARLTSE 364
Score = 76.3 bits (186), Expect = 8e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 545 VPRDQTPDENEEVI 558
V D P+ E +
Sbjct: 165 VAGDMLPNSTERAV 178
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 79.0 bits (193), Expect = 1e-14
Identities = 86/359 (23%), Positives = 155/359 (43%), Gaps = 55/359 (15%)
Query: 184 GGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVT 243
G T + +R+L+ + VG+IIGK+G ++K I +++ +R++I E+ +T
Sbjct: 4 GVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERIIT 60
Query: 244 IHATPEGTSEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNL 297
+ +A MI++ ++++ + + + L+++ G LIGK G +
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEI----MKKLREAFENDM 353
K+I TG ++ ++ D+ + ER IT+ G ++ +I ++ L ++ + +
Sbjct: 121 KEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178
Query: 354 LAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGA------PPAAPYHPFTTHS---- 403
+ + Q + S+ I + G S AG A PP Y H+
Sbjct: 179 MTIPYQP-----MPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPL 233
Query: 404 ------------GYFSSLYPHHQFGPF----PHHHSY------PEQEIVNLFIPTQAVGA 441
+F+ ++ F P Y Q L IP +G
Sbjct: 234 DLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGC 293
Query: 442 IIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
IIG++GA+I ++ + +GA IKIA P EG S R V ITG + AQ I +L E
Sbjct: 294 IIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITGSAASISLAQYLINARLSSE 350
Score = 76.3 bits (186), Expect = 8e-14
Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 12/168 (7%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ +TGP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP++ G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 592
V D P+ E I I G Q+ +++I + + + PQG
Sbjct: 133 VAGDMLPNSTERAIT-IAG---VPQSVTECVKQICLVMLETLSQSPQG 176
Score = 49.7 bits (117), Expect = 8e-06
Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M E+ L + +++L H VG +IGK+G ++K+I E+G +I IS P
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CP 55
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDM 353
ER IT+ G A A I+ KL E + M
Sbjct: 56 ERIITLTGPTNAIFKAFAMIIDKLEEDINSSM 87
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ +
Sbjct: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECV 159
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530
+I + E +P+ V + +P+S+ VI GG+
Sbjct: 160 KQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 79.0 bits (193), Expect = 1e-14
Identities = 79/317 (24%), Positives = 142/317 (44%), Gaps = 26/317 (8%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIP- 364
++ ++ D+ + ER IT+ G ++ IE +K++ ML + IP
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQICVV----MLESPPKGVTIPY 178
Query: 365 -GLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHS 423
S+ IF+ G + P H +F H G +
Sbjct: 179 RPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFP--MTHGNTGFSAGLDA 236
Query: 424 YPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPP 482
+ L IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG
Sbjct: 237 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSA 294
Query: 483 EAQFKAQGRIFGKLKEE 499
+ AQ I +L E
Sbjct: 295 ASISLAQYLINVRLSSE 311
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/190 (27%), Positives = 97/190 (51%), Gaps = 10/190 (5%)
Query: 413 HQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 472
+Q G H + +E +P + VG IIG+ G I ++ +G I+IA +E +
Sbjct: 66 NQLGALVHQRTVITEEFK---VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIP 121
Query: 473 ERMVIITGPPEAQFKAQGRIFGKLKEE-----NFFNPKEEVKLEAHIRVPSSTAGRVIGK 527
ER ++TG PE+ +A+ R+ G++ + F N + I +P+S G VIG+
Sbjct: 122 ERPCVLTGTPESIEQAK-RLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
Query: 528 GGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
GG+T+ +LQ T ++++ +D + +RI G F Q A+ + EI+++ Q +
Sbjct: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
Query: 588 KYPQGVASQR 597
+ +G + R
Sbjct: 241 RGVRGDFNSR 250
Score = 57.4 bits (137), Expect = 4e-08
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 9/168 (5%)
Query: 200 VPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL 259
VP + VG IIG+ G I I ++ ++ I E+SG E+P + TPE +A R++
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
Query: 260 EIMQKEADETKLAEEIP-----LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQ 314
+I+ + + +I +IL VG +IG+ G +K+++ TG K+ + +Q
Sbjct: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
Query: 315 DLSI-YNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQAN 361
D + ++ + + G A +++ +RE + D V N
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFN 248
Score = 56.6 bits (135), Expect = 6e-08
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 13/165 (7%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAAEKPVTIHATPEGTSEACR 256
IL+P VG +IG+ G TIK + ++T + V I A+KP+ I +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 257 MILEIMQK--EADETKLAEEI-------PLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
M+LEI+++ +AD + + +++ VG +IG+ G +KKI+++ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 308 ITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFEND 352
I +S PER V G + C A I + + A E D
Sbjct: 287 IQFKPDDGIS---PERAAQVMGPPDRCQHAAHIISELILTAQERD 328
Score = 54.7 bits (130), Expect = 2e-07
Identities = 75/317 (23%), Positives = 123/317 (38%), Gaps = 52/317 (16%)
Query: 285 LVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI---EI 341
+VG +IG+ G + +I+ E+G KI I+S S PER + GT E+ A+ +I
Sbjct: 88 MVGFIIGRGGEQISRIQAESGCKIQIASE---SSGIPERPCVLTGTPESIEQAKRLLGQI 144
Query: 342 MKKLREA--FENDMLAVNQ-QANLIPGLNLS-ALGIFSTGLSVLSPPAGPR------GAP 391
+ + R F ND+ + + Q LIP + +G + L G + G
Sbjct: 145 VDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL 204
Query: 392 PAAPYHPFTTHSGYFSSLYPHHQF-------------GPFPHHHSYPEQEIVNLFIPTQA 438
P P F G +S + + +P A
Sbjct: 205 PTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFA 264
Query: 439 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKL-- 496
VG +IG+ G IK++ AG I+ P +G ER + GPP+ + + I +L
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGIS-PERAAQVMGPPD-RCQHAAHIISELIL 322
Query: 497 --KEENFFNPKEEVK-----------------LEAHIRVPSSTAGRVIGKGGKTVNELQN 537
+E + F + E VP+ G VIGKGG+ + +
Sbjct: 323 TAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQ 382
Query: 538 LTSAEVIVPRDQTPDEN 554
+ A V + R+ P+ +
Sbjct: 383 QSGAHVELQRNPPPNSD 399
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/195 (23%), Positives = 83/195 (42%), Gaps = 17/195 (8%)
Query: 416 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGAS-IKIAPAEGPDVSER 474
GP H+ I + IP VG +IG+ G IKQL G + I P +++
Sbjct: 151 GPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADK 210
Query: 475 MVIITGPPEAQFKAQGRIFGKLKEEN---FFNPKEEVKLEA-----HIRVPSSTAGRVIG 526
+ ITG +A+ + ++E++ F + + + VP G VIG
Sbjct: 211 PLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIG 270
Query: 527 KGGKTVNELQNLTSAEVIVPRDQTPDE--NEEVIVRIIGHFFASQTAQRKIREIVQQVKQ 584
+ G+ + ++QN + PD+ + E +++G Q A I E++ +
Sbjct: 271 RNGEMIKKIQNDAGVRI----QFKPDDGISPERAAQVMGPPDRCQHAAHIISELI--LTA 324
Query: 585 QEQKYPQGVASQRSK 599
QE+ G+A+ R +
Sbjct: 325 QERDGFGGLAAARGR 339
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/277 (21%), Positives = 98/277 (35%), Gaps = 78/277 (28%)
Query: 168 RAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRV 227
R RGD +SR G + + + VP VG +IG+ G IK I Q + V
Sbjct: 241 RGVRGDFNSRMGGGS-------------IEVSVPRFAVGIVIGRNGEMIKKI--QNDAGV 285
Query: 228 DIHRKENSGAA-EKPVTIHATPEGTSEACRMILEIMQKEADETKLA-------------- 272
I K + G + E+ + P+ A +I E++ +
Sbjct: 286 RIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
Query: 273 ---------EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPER 323
+EI + A G +IGK G N+K I ++G + + + R
Sbjct: 346 WSVGAPGGVQEITYTVPADK--CGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLR 403
Query: 324 TITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSP 383
T++G + +IE+ ++L + + G NL A G F
Sbjct: 404 RFTIRGVPQ-----QIEVARQLID-------------EKVGGTNLGAPGAFG-------- 437
Query: 384 PAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
P PPA P+ + +P G FP+
Sbjct: 438 -QSPFSQPPAPPH----------QNTFPPRSSGCFPN 463
Score = 30.8 bits (68), Expect = 3.7
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 434 IPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEGPDVSERMVIITGPPE 483
+P G +IGK G +IK + + +GA +++ P D + R I G P+
Sbjct: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQ 412
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 77.8 bits (190), Expect = 3e-14
Identities = 78/328 (23%), Positives = 143/328 (43%), Gaps = 31/328 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIP- 364
++ ++ D+ + ER IT+ G ++ IE +K++ + + IP
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQICVVMLETLSQSPPKGVTIPY 182
Query: 365 -GLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPF----P 419
S+ IF+ G + P H +F + + F P
Sbjct: 183 RPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSP 242
Query: 420 HHHSY-------PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDV 471
Y + L IP +G IIG++GA I ++ + +GA IKIA P EG
Sbjct: 243 EVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS-- 300
Query: 472 SERMVIITGPPEAQFKAQGRIFGKLKEE 499
++R V ITG + AQ I +L E
Sbjct: 301 TDRQVTITGSAASISLAQYLINVRLSSE 328
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ +
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530
+I + E +P + V + P ++ VI GG+
Sbjct: 160 KQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 77.0 bits (188), Expect = 5e-14
Identities = 80/328 (24%), Positives = 144/328 (43%), Gaps = 35/328 (10%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIP- 364
++ ++ D+ + ER IT+ G ++ IE +K++ ML + IP
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQICVV----MLESPPKGVTIPY 178
Query: 365 -GLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPF----P 419
S+ IF+ G + P H +F + + F P
Sbjct: 179 RPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSP 238
Query: 420 HHHSY-------PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDV 471
Y + L IP +G IIG++GA I ++ + +GA IKIA P EG
Sbjct: 239 EVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS-- 296
Query: 472 SERMVIITGPPEAQFKAQGRIFGKLKEE 499
++R V ITG + AQ I +L E
Sbjct: 297 TDRQVTITGSAASISLAQYLINVRLSSE 324
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 76.6 bits (187), Expect = 6e-14
Identities = 83/309 (26%), Positives = 135/309 (43%), Gaps = 33/309 (10%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
Query: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
Query: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQAN 361
TG ++ ++ DL + ER +TV G +A +I + E+ +
Sbjct: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
Query: 362 LIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHH 421
+ + LSA + G SV G GA A T S P P
Sbjct: 187 SLGTVLLSA----NQGFSV----QGQYGAVTPA---EVTKLQQLSSHAVPFATPSVVPGL 235
Query: 422 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITG 480
+ +P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITG 293
Query: 481 PPEAQFKAQ 489
P + AQ
Sbjct: 294 SPVSIALAQ 302
Score = 61.2 bits (147), Expect = 3e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 439 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 498
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
Query: 499 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 553
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
Query: 554 NEEVI 558
E +
Sbjct: 146 TERAV 150
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
Query: 327 VKGTVEACASAEIEIMKKLRE 347
+ G+ A A I KL E
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE 85
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 543
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
VT+ P+ + C +ILE K
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
Query: 265 EADETKL----AEEIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
Score = 30.8 bits (68), Expect = 3.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 494 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 76.6 bits (187), Expect = 6e-14
Identities = 83/309 (26%), Positives = 135/309 (43%), Gaps = 33/309 (10%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
Query: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
Query: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQAN 361
TG ++ ++ DL + ER +TV G +A +I + E+ +
Sbjct: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
Query: 362 LIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHH 421
+ + LSA + G SV G GA A T S P P
Sbjct: 187 SLGTVLLSA----NQGFSV----QGQYGAVTPA---EVTKLQQLSSHAVPFATPSVVPGL 235
Query: 422 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITG 480
+ +P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG
Sbjct: 236 DPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITG 293
Query: 481 PPEAQFKAQ 489
P + AQ
Sbjct: 294 SPVSIALAQ 302
Score = 61.2 bits (147), Expect = 3e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 439 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 498
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
Query: 499 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 553
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
Query: 554 NEEVI 558
E +
Sbjct: 146 TERAV 150
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
Query: 327 VKGTVEACASAEIEIMKKLRE 347
+ G+ A A I KL E
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE 85
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 543
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
VT+ P+ + C +ILE K
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
Query: 265 EADETKL----AEEIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
Score = 30.8 bits (68), Expect = 3.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 494 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 74.3 bits (181), Expect = 3e-13
Identities = 86/354 (24%), Positives = 151/354 (42%), Gaps = 57/354 (16%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVNQQANLIP 364
++ ++ D+ + ER IT+ G ++ +I + E+ + + + + P
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 365 GLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH---- 412
+ +STG S P P PP Y T G ++ P
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPDLTKL 242
Query: 413 HQF----GPFPHHH----------SYPEQE------------IVNLFIPTQAVGAIIGKK 446
HQ FP H S PE + L IP +G IIG++
Sbjct: 243 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQ 302
Query: 447 GAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 303 GAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 354
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 73.9 bits (180), Expect = 4e-13
Identities = 86/358 (24%), Positives = 149/358 (41%), Gaps = 61/358 (17%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFEND-----MLAVNQQA 360
++ ++ D+ + ER IT+ G ++ +I + E + +
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 361 NLIPGLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH 412
+ P + +STG S P P PP Y T G ++ P
Sbjct: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPD 242
Query: 413 ----HQF----GPFPHHH----------SYPEQE------------IVNLFIPTQAVGAI 442
HQ FP H S PE + L IP +G I
Sbjct: 243 LTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCI 302
Query: 443 IGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
IG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 303 IGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 358
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ +
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530
+I + E +P + V + P ++ VI GG+
Sbjct: 160 KQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 73.9 bits (180), Expect = 4e-13
Identities = 86/355 (24%), Positives = 151/355 (42%), Gaps = 58/355 (16%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVNQQANLIP 364
++ ++ D+ + ER IT+ G ++ +I + E+ + + + + P
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 365 GLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH---- 412
+ +STG S P P PP Y T G ++ P
Sbjct: 187 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPDLTKL 242
Query: 413 HQF----GPFPHHH----------SYPEQE-------------IVNLFIPTQAVGAIIGK 445
HQ FP H S PE + L IP +G IIG+
Sbjct: 243 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGR 302
Query: 446 KGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
+GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 303 QGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 355
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 545 VPRDQTPDENEEVI 558
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 73.6 bits (179), Expect = 5e-13
Identities = 86/359 (23%), Positives = 149/359 (41%), Gaps = 62/359 (17%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFEND-----MLAVNQQA 360
++ ++ D+ + ER IT+ G ++ +I + E + +
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
Query: 361 NLIPGLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH 412
+ P + +STG S P P PP Y T G ++ P
Sbjct: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPD 242
Query: 413 ----HQF----GPFPHHH----------SYPEQE-------------IVNLFIPTQAVGA 441
HQ FP H S PE + L IP +G
Sbjct: 243 LTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGC 302
Query: 442 IIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
IIG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 303 IIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 359
Score = 43.1 bits (100), Expect = 7e-04
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ +
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530
+I + E +P + V + P ++ VI GG+
Sbjct: 160 KQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 72.8 bits (177), Expect = 9e-13
Identities = 64/226 (28%), Positives = 100/226 (44%), Gaps = 36/226 (15%)
Query: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 337 AEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSP--PAGPRGAPPAA 394
I +K+RE +N A P +S+L P P
Sbjct: 112 VHGFIAEKIREMPQN-------VAKTEP-------------VSILQPQTTVNPDRIKQTL 151
Query: 395 PYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLA 454
P P TT S P S Q V + +P G IIGK GA +K +
Sbjct: 152 PSSPTTTKSSPSD-----------PMTTSRANQ--VKIIVPNSTAGLIIGKGGATVKAVM 198
Query: 455 RFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
+GA ++++ +G ++ ER+V ++G PE KA I K++E+
Sbjct: 199 EQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244
Score = 60.1 bits (144), Expect = 6e-09
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 485 QFKAQGRIFGKLKE----------------ENFFNPKEEVKL------------------ 510
G I K++E + NP + +K
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP-DRIKQTLPSSPTTTKSSPSDPMT 167
Query: 511 -----EAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHF 565
+ I VP+STAG +IGKGG TV + + A V + + +E +V + G
Sbjct: 168 TSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE- 226
Query: 566 FASQTAQRKIREIVQQVKQQEQ 587
+ ++ + I+Q++++ Q
Sbjct: 227 --PEQNRKAVELIIQKIQEDPQ 246
Score = 59.3 bits (142), Expect = 1e-08
Identities = 90/358 (25%), Positives = 136/358 (37%), Gaps = 68/358 (18%)
Query: 183 PGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKP 241
P TS+A Q+ +I+VP G IIGK G T+K + +Q+ + V + +K + E+
Sbjct: 165 PMTTSRANQV----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 220
Query: 242 VTIHATPEGTSEACRMILEIMQKEADE-------------------------TKLAEEIP 276
VT+ PE +A +I++ +Q++ AE +P
Sbjct: 221 VTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP 280
Query: 277 LK-----ILAHNGLVG------RLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTI 325
+L H L G L G G +L I S+L L+ Y
Sbjct: 281 TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAI---------TSALNTLASYGYNLNT 331
Query: 326 TVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFST-GLSVLSPP 384
G +A A+ + A N A ANL+ A ST G + +
Sbjct: 332 LGLGLSQAAATGAL----AAAAASANPAAAA---ANLLATYASEASASGSTAGGTAGTFA 384
Query: 385 AGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYP-EQEIVNLFIPTQAVGAII 443
G A AA +GYF + P S +++V + +P VGAI+
Sbjct: 385 LGSLAAATAAT-------NGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAIL 437
Query: 444 GKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
GK G + + GA I+I+ P R V ITG P A AQ I ++ E
Sbjct: 438 GKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 495
Score = 55.1 bits (131), Expect = 2e-07
Identities = 105/500 (21%), Positives = 173/500 (34%), Gaps = 86/500 (17%)
Query: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
Query: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIM------------------QK 264
+ + + + ++ G E+ I T E + I E + Q
Sbjct: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
Query: 265 EADETKLAEEIP---------------------LKILAHNGLVGRLIGKEGRNLKKIEHE 303
+ ++ + +P +KI+ N G +IGK G +K + +
Sbjct: 141 TVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ 200
Query: 304 TGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI 363
+G + +S D I ER +TV G E A I++K++E ++ AN+
Sbjct: 201 SGAWVQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVT 259
Query: 364 -PGLNLSALGI-FSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHH 421
P N + G ++ VL A G A S +
Sbjct: 260 GPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVA----- 314
Query: 422 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGP 481
I + + G + G + Q A GA A + P + ++ T
Sbjct: 315 -------ITSALNTLASYGYNLNTLGLGLSQAAA-TGALAAAAASANPAAAAANLLATYA 366
Query: 482 PEAQFK-----------AQGRIFGKLKEEN-FFNPKEEVKLEAHIRVPSSTAG------- 522
EA A G + N +F + A + ST G
Sbjct: 367 SEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEI 426
Query: 523 --------RVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQR 573
++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 427 AVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQY 486
Query: 574 KIREIVQQVKQQEQKYPQGV 593
I + + + PQ V
Sbjct: 487 LITQRITYEQGVRAANPQKV 506
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
Query: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
Query: 566 FASQTAQ----RKIREIVQQVKQQE 586
A KIRE+ Q V + E
Sbjct: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 72.8 bits (177), Expect = 9e-13
Identities = 86/351 (24%), Positives = 145/351 (41%), Gaps = 77/351 (21%)
Query: 155 IPDEEVSSPSPPQRAQRG-----DHSSREQGHAPG---GTSQARQIDFPLRILVPTQFVG 206
+P+ VS P+ Q+ D SR +G PG + Q I++P G
Sbjct: 187 LPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAG 246
Query: 207 AIIGKEGLTIKNITKQTQSRVDIHRKENSGA-AEKPVTIHATPEGTSEACRMILEIMQKE 265
+IGK G TIK + ++ ++ + + + +KP+ I P +AC M+++I+ +E
Sbjct: 247 LVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDIL-RE 305
Query: 266 ADE----------TKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315
D+ +++ I + + H+ VG +IG+ G +KKI+++ G +I QD
Sbjct: 306 RDQGGFGDRNEYGSRIGGGIDVPVPRHS--VGVVIGRSGEMIKKIQNDAGVRIQFK--QD 361
Query: 316 LSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFS 375
PE+ + G + C A I ND+L
Sbjct: 362 DGT-GPEKIAHIMGPPDRCEHAARII---------NDLLQ-------------------- 391
Query: 376 TGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIP 435
S+ S P GP G P P G +GP P E + IP
Sbjct: 392 ---SLRSGPPGPPGGPGMPP--------GGRGRGRGQGNWGP-------PGGE-MTFSIP 432
Query: 436 TQAVGAIIGKKGAHIKQLARFAGASIKIA---PAEGPDVSERMVIITGPPE 483
T G +IG+ G ++K + + GA ++I+ P G D + ++ II G P+
Sbjct: 433 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNG-DPNFKLFIIRGSPQ 482
Score = 71.2 bits (173), Expect = 2e-12
Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%)
Query: 414 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 472
Q GP H P + + +P VG IIG+ G I ++ + +G ++I+P G +
Sbjct: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188
Query: 473 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 523
ER V +TG PE+ KA+ + + P + A+ I +P+ AG
Sbjct: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247
Query: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 583
VIGKGG+T+ +LQ ++I+ +D + + N + +RIIG + Q A + +I+++
Sbjct: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307
Query: 584 Q 584
Q
Sbjct: 308 Q 308
Score = 52.8 bits (125), Expect = 9e-07
Identities = 78/318 (24%), Positives = 126/318 (39%), Gaps = 75/318 (23%)
Query: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342
+G+VG +IG+ G + KI+ ++G K+ IS S PER++++ G E+ A++ +
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMMLD 209
Query: 343 KKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTH 402
I S G RG PP
Sbjct: 210 -----------------------------DIVSRG----------RGGPP---------- 220
Query: 403 SGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIK 462
G F Q G QEI+ IP G +IGK G IKQL AG +
Sbjct: 221 -GQFHDNANGGQNGTV--------QEIM---IPAGKAGLVIGKGGETIKQLQERAGVKMI 268
Query: 463 IAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--ENFFNPKEE----VKLEAHI 514
+ ++ +V + + II P + Q +A + L+E + F + E + +
Sbjct: 269 LIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQGGFGDRNEYGSRIGGGIDV 327
Query: 515 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRK 574
VP + G VIG+ G+ + ++QN A V + Q E I I+G + A R
Sbjct: 328 PVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 575 IREIVQQVKQQEQKYPQG 592
I +++Q ++ P G
Sbjct: 386 INDLLQSLRSGPPGPPGG 403
Score = 50.1 bits (118), Expect = 6e-06
Identities = 68/285 (23%), Positives = 102/285 (35%), Gaps = 68/285 (23%)
Query: 167 QRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR 226
+R Q G E G GG ID P VP VG +IG+ G IK I R
Sbjct: 305 ERDQGGFGDRNEYGSRIGGG-----IDVP----VPRHSVGVVIGRSGEMIKKIQNDAGVR 355
Query: 227 VDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQK---------------------- 264
+ + + +G EK I P+ A R+I +++Q
Sbjct: 356 IQFKQDDGTGP-EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG 414
Query: 265 --EADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322
+ + E+ I H G +IG+ G N+K I +TG + IS +
Sbjct: 415 RGQGNWGPPGGEMTFSIPTHK--CGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNF 472
Query: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLS 382
+ ++G+ + A+ + + E E + V PG
Sbjct: 473 KLFIIRGSPQQIDHAK----QLIEEKIEGPLCPVG------PG----------------- 505
Query: 383 PPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQ 427
P GP A P P++P + G + P H GP P H YP Q
Sbjct: 506 -PGGPGPAGPMGPFNPGPFNQGPPGA--PPHAGGPPP--HQYPPQ 545
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 32/149 (21%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+++ +P +VG +IG+ G IK++ AG I+ +G E++ I GPP+ + +
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCEHA 382
Query: 490 GRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTAGR 523
RI L + N+ P E+ +P+ G
Sbjct: 383 ARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGL 438
Query: 524 VIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
VIG+GG+ V + T A V + R P+
Sbjct: 439 VIGRGGENVKAINQQTGAFVEISRQLPPN 467
Score = 33.1 bits (74), Expect = 0.75
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%)
Query: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220
P P G R QG+ PGG + +PT G +IG+ G +K I
Sbjct: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451
Query: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
+QT + V+I R+ N K I +P+ A ++I E
Sbjct: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 71.2 bits (173), Expect = 2e-12
Identities = 45/152 (29%), Positives = 81/152 (53%), Gaps = 7/152 (4%)
Query: 434 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIF 493
+P VG IIG+ G I ++ + +G I+IAP G + ER ++TG PE+ A+ R+
Sbjct: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG-GLPERSCMLTGTPESVQSAK-RLL 164
Query: 494 GKLKEEN-----FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 548
++ E+ F + I +P+S AG VIGKGG+T+ +LQ ++++ +D
Sbjct: 165 DQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
Query: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQ 580
+ + +RI G + Q A+ + E+++
Sbjct: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELIR 256
Score = 67.4 bits (163), Expect = 4e-11
Identities = 77/315 (24%), Positives = 123/315 (39%), Gaps = 71/315 (22%)
Query: 180 GHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAA 238
G PG Q I++P G +IGK G TIK + ++ + V I + A
Sbjct: 180 GDGPGNAVQ--------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA 231
Query: 239 EKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGL--------VGRLI 290
+KP+ I P +A M+LE+++ + ++ E +I + G+ VG +I
Sbjct: 232 DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVI 291
Query: 291 GKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE 350
G+ G +KKI+++ G +I + PER + G + C A EI+
Sbjct: 292 GRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHA-AEII-------- 339
Query: 351 NDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLY 410
D+L Q N PG P G RG
Sbjct: 340 TDLLRSVQAGN--PG----------------GPGPGGRGRGRG----------------Q 365
Query: 411 PHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEG 468
+ GP + N +PT G IIGK G IK +++ +GA I++ P
Sbjct: 366 GNWNMGPPGGLQEF------NFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
Query: 469 PDVSERMVIITGPPE 483
D + ++ I G P+
Sbjct: 420 ADPNMKLFTIRGTPQ 434
Score = 67.0 bits (162), Expect = 5e-11
Identities = 81/336 (24%), Positives = 138/336 (41%), Gaps = 53/336 (15%)
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M ++ + + EE + +G+VG +IG+ G + +I+ E+G KI I+ S P
Sbjct: 92 MHQQQSRSVMTEEYKVP----DGMVGFIIGRGGEQISRIQQESGCKIQIAPD---SGGLP 144
Query: 322 ERTITVKGTVEACASAEI---EIMKKLREA-----------FENDMLAVNQQANLIPGLN 367
ER+ + GT E+ SA+ +I++K R A +++ +A L+ G
Sbjct: 145 ERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKG 204
Query: 368 LSALGIFS--TGLSVLSPPAGPRGAPPAAPYH----PFTTHSGYFSSLYPHHQFGPFPH- 420
+ G+ ++ GP+ P P+ L G F
Sbjct: 205 GETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREV 264
Query: 421 HHSYPEQ----EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 476
+ Y + E +++ IP AVG +IG+ G IK++ AG I+ P +G ER+
Sbjct: 265 RNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDG-TTPERIA 323
Query: 477 IITGPPEAQFKAQGRIFGKLKEENFFNP--------------------KEEVKLEAHIRV 516
ITGPP+ A I L+ NP E + V
Sbjct: 324 QITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIV 383
Query: 517 PSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 552
P+ G +IGKGG+T+ + + A + + R+ P+
Sbjct: 384 PTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/177 (25%), Positives = 78/177 (44%), Gaps = 20/177 (11%)
Query: 420 HHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD--VSERMVI 477
HH P + + IP G +IGK G IKQL AG + + +GP +++ +
Sbjct: 178 HHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM-VMIQDGPQNTGADKPLR 236
Query: 478 ITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLE----------AHIRVPSSTAGRVIGK 527
ITG P +A+ + ++++ F EV+ E + +P G VIG+
Sbjct: 237 ITGDPYKVQQAKEMVLELIRDQGGF---REVRNEYGSRIGGNEGIDVPIPRFAVGIVIGR 293
Query: 528 GGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 583
G+ + ++QN + P D T E I +I G Q A I ++++ V+
Sbjct: 294 NGEMIKKIQNDAGVRIQFKPDDGTTPER---IAQITGPPDRCQHAAEIITDLLRSVQ 347
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 15/108 (13%)
Query: 159 EVSSPSPPQRAQRGDHSSREQGH----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGL 214
+ +P P RG R QG+ PGG + +VPT G IIGK G
Sbjct: 347 QAGNPGGPGPGGRG--RGRGQGNWNMGPPGGLQE-------FNFIVPTGKTGLIIGKGGE 397
Query: 215 TIKNITKQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
TIK+I++Q+ +R+++ R N+ K TI TP+ A ++I E
Sbjct: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEE 445
Score = 38.1 bits (87), Expect = 0.023
Identities = 58/265 (21%), Positives = 92/265 (34%), Gaps = 54/265 (20%)
Query: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
E G GG ID P +P VG +IG+ G IK I Q + V I K + G
Sbjct: 267 EYGSRIGGNEG---IDVP----IPRFAVGIVIGRNGEMIKKI--QNDAGVRIQFKPDDGT 317
Query: 238 A-EKPVTIHATPEGTSEACRMILEIMQ------------------KEADETKLAEEIPLK 278
E+ I P+ A +I ++++ + + L+
Sbjct: 318 TPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQ 377
Query: 279 ---ILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACA 335
+ G G +IGK G +K I ++G +I + + + T++GT +
Sbjct: 378 EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQID 437
Query: 336 SAEIEIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAP 395
A I +K+ V + +PG + PP P P P
Sbjct: 438 YARQLIEEKIGGPVNPLGPPVPHGPHGVPGPH--------------GPPGPPGPGTPMGP 483
Query: 396 YHPFTTHSGYFSSLYPHHQFGPFPH 420
Y+P + G GP PH
Sbjct: 484 YNPAPYNPG---------PPGPAPH 499
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 69.3 bits (168), Expect = 9e-12
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)
Query: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 485 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 530
G I K++E + P+ V + I VP+STAG +IGKGG
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
Query: 531 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
TV + + A V + + +E +V + G + ++ + I+Q++++ Q
Sbjct: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
Score = 63.9 bits (154), Expect = 4e-10
Identities = 104/476 (21%), Positives = 170/476 (35%), Gaps = 62/476 (13%)
Query: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
Query: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277
+ + + + ++ G E+ I T E + I E +++ E + +
Sbjct: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
Query: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
KI+ N G +IGK G +K + ++G + +S D I ER +TV
Sbjct: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
Query: 328 KGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI-PGLNLSALGI-FSTGLSVLSPPA 385
G E A I++K++E ++ AN+ P N + G ++ VL A
Sbjct: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA 259
Query: 386 GPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445
G A S + I + + G +
Sbjct: 260 AAAGLLGHANLAGVAAFPAVLSGFTGNDLVA------------ITSALNTLASYGYNLNT 307
Query: 446 KGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK-----------AQGRIFG 494
G + Q A GA A + P + ++ T EA A G +
Sbjct: 308 LGLGLSQAAA-TGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAA 366
Query: 495 KLKEEN-FFNPKEEVKLEAHIRVPSSTAG---------------RVIGKGGKTVNELQNL 538
N +F + A + ST G ++GKGGKT+ E Q L
Sbjct: 367 ATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQEL 426
Query: 539 TSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593
T A + I + + V I G A+Q AQ I + + + PQ V
Sbjct: 427 TGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKV 482
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
Query: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
Query: 566 FASQTAQ----RKIREIVQQVKQQE 586
A KIRE+ Q V + E
Sbjct: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 68.6 bits (166), Expect = 2e-11
Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 19/174 (10%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFK 487
+ + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ ++ G EA
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 488 AQGRIFGKLKE----------ENFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGKTVN 533
I K++E N P+ + +A + VP+STAG +IGKGG TV
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 534 ELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
+ + A V + + +E +V + G + + + IVQ+V++ Q
Sbjct: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
Score = 60.8 bits (146), Expect = 3e-09
Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 28/220 (12%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEG 250
++ L++L+P+ G+IIGK G TI + K+T + + + + ++ G E+ + T E
Sbjct: 32 EYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA 91
Query: 251 -------TSEACRMILEIMQKEADETKLAEEIPL--------KILAHNGLVGRLIGKEGR 295
+E R I + M K L + + K++ N G +IGK G
Sbjct: 92 LNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGA 151
Query: 296 NLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLA 355
+K + ++G + +S + I ER +TV G E A I++K++E ++
Sbjct: 152 TVKAVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCL 210
Query: 356 VNQQANLI-PGLNLSALGIFSTGLSVLSPPAGPRGAPPAA 394
AN+ P N + G SP A P PAA
Sbjct: 211 NISYANVAGPVANSNPTG---------SPYASPADVLPAA 241
Score = 56.6 bits (135), Expect = 6e-08
Identities = 94/405 (23%), Positives = 148/405 (36%), Gaps = 55/405 (13%)
Query: 197 RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKPVTIHATPEGTSEAC 255
+++VP G IIGK G T+K + +Q+ + V + +K E E+ VT+ PE +A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315
I++ +Q++ + +++ + G + + TG+ S
Sbjct: 194 SAIVQKVQEDPQSSSCLN------ISYANVAGPVANS---------NPTGSPYA-SPADV 237
Query: 316 LSIYNPERTITVKGTVEACASAEIEIMKKLREAFEN-DMLAVNQQANLIP--GLNLSALG 372
L G + A + AF D+LA++ N + G N ++LG
Sbjct: 238 LPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLG 297
Query: 373 I---FSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 429
+ + VL+ A AA + +++G + P P P P
Sbjct: 298 LGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGE-AGAGPAGGAAPPPP----PPPGA 352
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ F A +G AGA GP V A A
Sbjct: 353 LGSFALAAAANGYLG------------AGAGGGAGGGGGPLV------------AAAAAA 388
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRD 548
G G L E E K I VP + G ++GKGGKT+ E Q LT A + I +
Sbjct: 389 GAAGGFLTAEKL--AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKG 446
Query: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593
+ V I G A+Q AQ I + V + PQ V
Sbjct: 447 EFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV 491
Score = 46.6 bits (109), Expect = 7e-05
Identities = 28/88 (31%), Positives = 45/88 (51%)
Query: 260 EIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIY 319
E++ + T E LK+L + G +IGK G+ + +++ ETG I +S +D
Sbjct: 18 EVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 77
Query: 320 NPERTITVKGTVEACASAEIEIMKKLRE 347
ER V+GT EA + I +K+RE
Sbjct: 78 TTERVCLVQGTAEALNAVHSFIAEKVRE 105
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
Query: 503 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVR 560
N EE + + +PS AG +IGKGG+T+ +LQ T A + + +D P E V +
Sbjct: 26 NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL- 84
Query: 561 IIGHFFASQTAQRKIREIVQQVKQQEQK 588
+ G A I E V+++ Q K
Sbjct: 85 VQGTAEALNAVHSFIAEKVREIPQAMTK 112
Score = 38.1 bits (87), Expect = 0.023
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI +P T
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 254 ACRMI 258
A +I
Sbjct: 469 AQYLI 473
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 32.0 bits (71), Expect = 1.7
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
D ER + + G A+ I + L E
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 507 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 566
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 567 ASQTAQRKIREIVQQ 581
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 32.0 bits (71), Expect = 1.7
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
D ER + + G A+ I + L E
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 507 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 566
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 567 ASQTAQRKIREIVQQ 581
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 32.0 bits (71), Expect = 1.7
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
D ER + + G A+ I + L E
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKAKAAIHQILTE 121
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 507 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 566
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 567 ASQTAQRKIREIVQQ 581
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 58.2 bits (139), Expect = 2e-08
Identities = 90/400 (22%), Positives = 163/400 (40%), Gaps = 53/400 (13%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
Query: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
Query: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVN---QQANLIPGLNLSA 370
S+ E T G E A A I K E + +AV Q + G ++
Sbjct: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 371 LG--IFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQE 428
L + TG+SV PP+ P + F
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF------------T 365
Query: 429 IVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKA 488
+ ++ P+ IIGKKG ++ ++ + + I EG D + + GP E A
Sbjct: 366 VSSVAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVA 420
Query: 489 QGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 548
Q +I G +K+ N + V+ I + +IGK G +N +++ V +P
Sbjct: 421 QEQIEGMVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP-- 472
Query: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQK 588
PD + ++RI G Q A+R++ E+ +++ + K
Sbjct: 473 --PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 11/153 (7%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
V + IP + ++IG KG I+ + G P EG V+I GP KA+
Sbjct: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSDVEKAK 713
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
++ +E K+ IR +IGKGG + ++++ T A VI P +
Sbjct: 714 KQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAE 767
Query: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 582
D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 768 DKDQD---LITIIGKEDAVREAQKELEALIQNL 797
Score = 44.3 bits (103), Expect = 3e-04
Identities = 90/449 (20%), Positives = 167/449 (37%), Gaps = 47/449 (10%)
Query: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
Query: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPG-LNLSALGIFSTGLSV 380
TI + G C +A I+ + + D+ + + IP L+ S +G +
Sbjct: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRS 678
Query: 381 LSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVG 440
+ G G P + + + H E++ + + +A
Sbjct: 679 IMEECG--GVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKP 736
Query: 441 A----IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKL 496
+IGK G I+++ GA + AE D + ++ I G +A +AQ +
Sbjct: 737 EYHKFLIGKGGGKIRKVRDSTGARVIFPAAE--DKDQDLITIIGKEDAVREAQKEL---- 790
Query: 497 KEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEE 556
E + V ++ + P VI +G + V PR T +
Sbjct: 791 --EALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDK-- 846
Query: 557 VIVRIIGHFFASQTAQRKIREIVQQVKQQ 585
V + G + A+++I+EI++ ++ Q
Sbjct: 847 --VTLKGAKDCVEAAKKRIQEIIEDLEAQ 873
Score = 43.9 bits (102), Expect = 4e-04
Identities = 82/364 (22%), Positives = 135/364 (37%), Gaps = 59/364 (16%)
Query: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
Query: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
Query: 340 EIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPR-GAPPAAPYHP 398
E+ L + E D AV ++ + + G ++ + + G R PP +
Sbjct: 211 EV---LLISAEQDKRAV-ERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRT 266
Query: 399 FTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAG 458
+G L + + + + + +IG KG ++++ G
Sbjct: 267 EIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTG 326
Query: 459 ASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPS 518
S++I P++ +SE VI+ G PE +A ++ K N F + + PS
Sbjct: 327 VSVEIPPSD--SISE-TVILRGEPEKLGQALTEVYAK---ANSFT-------VSSVAAPS 373
Query: 519 STAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREI 578
+IGK G QNL +P+ E + + G AQ +I +
Sbjct: 374 WLHRFIIGKKG------QNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGM 427
Query: 579 VQQV 582
V+ +
Sbjct: 428 VKDL 431
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
Query: 303 E 303
E
Sbjct: 1156 E 1156
Score = 37.7 bits (86), Expect = 0.030
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 442 IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKE 498
IIG+KGA I Q+ +I+ + + + + ITG EA A RI G+L++
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Query: 499 ENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 554
E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 1127 M----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 58.2 bits (139), Expect = 2e-08
Identities = 90/400 (22%), Positives = 163/400 (40%), Gaps = 53/400 (13%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
Query: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
Query: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDM-LAVN---QQANLIPGLNLSA 370
S+ E T G E A A I K E + +AV Q + G ++
Sbjct: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 371 LG--IFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQE 428
L + TG+SV PP+ P + F
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSF------------T 365
Query: 429 IVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKA 488
+ ++ P+ IIGKKG ++ ++ + + I EG D + + GP E A
Sbjct: 366 VSSVAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVA 420
Query: 489 QGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 548
Q +I G +K+ N + V+ I + +IGK G +N +++ V +P
Sbjct: 421 QEQIEGMVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP-- 472
Query: 549 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQK 588
PD + ++RI G Q A+R++ E+ +++ + K
Sbjct: 473 --PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 11/153 (7%)
Query: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
V + IP + ++IG KG I+ + G P EG V+I GP KA+
Sbjct: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSDVEKAK 713
Query: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 549
++ +E K+ IR +IGKGG + ++++ T A VI P +
Sbjct: 714 KQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAE 767
Query: 550 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 582
D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 768 DKDQD---LITIIGKEDAVREAQKELEALIQNL 797
Score = 44.3 bits (103), Expect = 3e-04
Identities = 90/449 (20%), Positives = 167/449 (37%), Gaps = 47/449 (10%)
Query: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
Query: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANLIPG-LNLSALGIFSTGLSV 380
TI + G C +A I+ + + D+ + + IP L+ S +G +
Sbjct: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRS 678
Query: 381 LSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVG 440
+ G G P + + + H E++ + + +A
Sbjct: 679 IMEECG--GVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKP 736
Query: 441 A----IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKL 496
+IGK G I+++ GA + AE D + ++ I G +A +AQ +
Sbjct: 737 EYHKFLIGKGGGKIRKVRDSTGARVIFPAAE--DKDQDLITIIGKEDAVREAQKEL---- 790
Query: 497 KEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEE 556
E + V ++ + P VI +G + V PR T +
Sbjct: 791 --EALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDK-- 846
Query: 557 VIVRIIGHFFASQTAQRKIREIVQQVKQQ 585
V + G + A+++I+EI++ ++ Q
Sbjct: 847 --VTLKGAKDCVEAAKKRIQEIIEDLEAQ 873
Score = 43.9 bits (102), Expect = 4e-04
Identities = 82/364 (22%), Positives = 135/364 (37%), Gaps = 59/364 (16%)
Query: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
Query: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
Query: 340 EIMKKLREAFENDMLAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPR-GAPPAAPYHP 398
E+ L + E D AV ++ + + G ++ + + G R PP +
Sbjct: 211 EV---LLISAEQDKRAV-ERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRT 266
Query: 399 FTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAG 458
+G L + + + + + +IG KG ++++ G
Sbjct: 267 EIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTG 326
Query: 459 ASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPS 518
S++I P++ +SE VI+ G PE +A ++ K N F + + PS
Sbjct: 327 VSVEIPPSD--SISE-TVILRGEPEKLGQALTEVYAK---ANSFT-------VSSVAAPS 373
Query: 519 STAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREI 578
+IGK G QNL +P+ E + + G AQ +I +
Sbjct: 374 WLHRFIIGKKG------QNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGM 427
Query: 579 VQQV 582
V+ +
Sbjct: 428 VKDL 431
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
Query: 303 E 303
E
Sbjct: 1156 E 1156
Score = 37.7 bits (86), Expect = 0.030
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 442 IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKE 498
IIG+KGA I Q+ +I+ + + + + ITG EA A RI G+L++
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Query: 499 ENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 554
E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 1127 M----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 53.1 bits (126), Expect = 7e-07
Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 20/155 (12%)
Query: 5 LYIGNLSPAVTADDLRQLFGDR---------KLPLAGQVLLKSGYAFVDYPDQNWAIRAI 55
L + L +T D+ + LFG + + GQ L GY FV+Y D N A +AI
Sbjct: 41 LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSL---GYGFVNYSDPNDADKAI 97
Query: 56 ETLSGKVELHGKIMEVDYS--VSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVEN--- 110
TL+G ++L K ++V Y+ S +R + + +P + + ++ L +QYG +
Sbjct: 98 NTLNG-LKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRI 156
Query: 111 -VEQVNTDTETAVVNVTYATREEAKIAMEKLSGHQ 144
V+QV T V + + R EA+ A++ L+G +
Sbjct: 157 LVDQV-TGVSRGVGFIRFDKRIEAEEAIKGLNGQK 190
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 53.1 bits (126), Expect = 7e-07
Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 20/155 (12%)
Query: 5 LYIGNLSPAVTADDLRQLFGDR---------KLPLAGQVLLKSGYAFVDYPDQNWAIRAI 55
L + L +T D+ + LFG + + GQ L GY FV+Y D N A +AI
Sbjct: 41 LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSL---GYGFVNYSDPNDADKAI 97
Query: 56 ETLSGKVELHGKIMEVDYS--VSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVEN--- 110
TL+G ++L K ++V Y+ S +R + + +P + + ++ L +QYG +
Sbjct: 98 NTLNG-LKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRI 156
Query: 111 -VEQVNTDTETAVVNVTYATREEAKIAMEKLSGHQ 144
V+QV T V + + R EA+ A++ L+G +
Sbjct: 157 LVDQV-TGVSRGVGFIRFDKRIEAEEAIKGLNGQK 190
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,964,272
Number of Sequences: 37866
Number of extensions: 1074597
Number of successful extensions: 4083
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 3400
Number of HSP's gapped (non-prelim): 629
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.