Guide to the Human Genome
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Search of human proteins with 62739163

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62739163 lethal giant larvae homolog 2 isoform b [Homo
sapiens]
         (356 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62739163 lethal giant larvae homolog 2 isoform b [Homo sapiens]    728   0.0  
gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens]    707   0.0  
gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens]    707   0.0  
gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]              343   2e-94
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom...   190   1e-48
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom...   190   1e-48
gi|149363700 syntaxin binding protein 5-like [Homo sapiens]           170   2e-42
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]      42   0.001
gi|94400919 WD repeat domain 90 [Homo sapiens]                         37   0.027
gi|55743075 angio-associated, migratory cell protein [Homo sapiens]    36   0.060
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ...    35   0.079
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...    35   0.079
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]          35   0.10 
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]            35   0.10 
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]          35   0.13 
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ...    35   0.13 
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ...    35   0.13 
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ...    35   0.13 
gi|188219762 denticleless homolog [Homo sapiens]                       33   0.39 
gi|38605733 nucleoporin 43kDa [Homo sapiens]                           33   0.39 
gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]       33   0.51 
gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]       33   0.51 
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]       33   0.51 
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]      33   0.51 
gi|14150171 THO complex 3 [Homo sapiens]                               33   0.51 
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]               32   0.87 
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]               32   0.87 
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]          32   1.1  
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]          32   1.1  
gi|221219004 WD repeat domain 74 [Homo sapiens]                        31   1.5  

>gi|62739163 lethal giant larvae homolog 2 isoform b [Homo sapiens]
          Length = 356

 Score =  728 bits (1878), Expect = 0.0
 Identities = 356/356 (100%), Positives = 356/356 (100%)

Query: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60
           MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG
Sbjct: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60

Query: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120
           APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR
Sbjct: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120

Query: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180
           GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE
Sbjct: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180

Query: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240
           EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR
Sbjct: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240

Query: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300
           DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF
Sbjct: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300

Query: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAASRRASGVGAQG 356
           QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAASRRASGVGAQG
Sbjct: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAASRRASGVGAQG 356


>gi|73427803 lethal giant larvae homolog 2 isoform c [Homo sapiens]
          Length = 1020

 Score =  707 bits (1826), Expect = 0.0
 Identities = 345/346 (99%), Positives = 346/346 (100%)

Query: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60
           MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG
Sbjct: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60

Query: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120
           APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR
Sbjct: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120

Query: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180
           GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE
Sbjct: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180

Query: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240
           EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR
Sbjct: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240

Query: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300
           DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF
Sbjct: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300

Query: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAAS 346
           QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAA+
Sbjct: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAAT 346


>gi|62739161 lethal giant larvae homolog 2 isoform a [Homo sapiens]
          Length = 1015

 Score =  707 bits (1826), Expect = 0.0
 Identities = 345/346 (99%), Positives = 346/346 (100%)

Query: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60
           MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG
Sbjct: 1   MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYG 60

Query: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120
           APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR
Sbjct: 61  APGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLR 120

Query: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180
           GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE
Sbjct: 121 GPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPE 180

Query: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240
           EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR
Sbjct: 181 EARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQR 240

Query: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300
           DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF
Sbjct: 241 DGRLLVSCHSDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKAITRILWLTTRQGLPFTIF 300

Query: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAAS 346
           QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAA+
Sbjct: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADPAAT 346


>gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]
          Length = 1064

 Score =  343 bits (879), Expect = 2e-94
 Identities = 178/347 (51%), Positives = 232/347 (66%), Gaps = 6/347 (1%)

Query: 3   RFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAP 62
           RF R G DP RE+LK++LF FNKTVEHGFP+QPSAL + P LRI+AIGTRSGA+K+YGAP
Sbjct: 5   RFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAP 64

Query: 63  GVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGP 122
           GVEF GLH++   VTQ+H L GQ +L++LLDD+SLHLW +    G + L+E  SF L   
Sbjct: 65  GVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSR 124

Query: 123 PG----AAP-SATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQR 177
           PG    +AP S T++TVVL  ++ ++  LGTE  +VF + +     LE +T++   VL+ 
Sbjct: 125 PGFDGASAPLSLTRVTVVLLVAAGDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGEVLRS 184

Query: 178 LPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIW 237
           +P++ R  +    VE+LQ H RDP +ILIGYSRGL+VIW+     V + FL +QQLE++ 
Sbjct: 185 VPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQLESLC 244

Query: 238 WQRDGRLLVSCHSDGSYCQWPVSSEA-QQPEPLRSLVPYGPFPCKAITRILWLTTRQGLP 296
           W RD   +VS HSDGSY  W V + +    +P  +  PYGPFPCKAI +ILW     G  
Sbjct: 245 WGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCESGGH 304

Query: 297 FTIFQGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTEADP 343
           F IF GGMPRASYGDRHC+SV+        DFTSR+I F  +    P
Sbjct: 305 FIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRP 351


>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
           sapiens]
          Length = 1151

 Score =  190 bits (483), Expect = 1e-48
 Identities = 111/338 (32%), Positives = 179/338 (52%), Gaps = 31/338 (9%)

Query: 12  VRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQ 71
           ++E L+ + FQ  KTV HGFP+QPSAL + P  +ILA+GT++GA++L+G PGVE    H 
Sbjct: 37  IQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHD 96

Query: 72  ENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQ 131
              AV Q+  L  +  LV+ L D++LHLW+L+ K  A  +     F             +
Sbjct: 97  SGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPA--ILHSLKFCRE----------R 144

Query: 132 ITVV-LPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEM 190
           +T   LP  S + LY+GTE GN+ +V + +F      T+S   ++     E   +     
Sbjct: 145 VTFCHLPFQS-KWLYVGTERGNIHIVNVESF------TLSGYVIMWNKAIELSSKSHPGP 197

Query: 191 VEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHS 250
           V  + ++P D  ++LIG+  G VV+WDL+  +  Y +   + + ++ W  +G+  +  HS
Sbjct: 198 VVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHS 257

Query: 251 DGSYCQWPVSSEAQQPEPLRSLVPYG--------PFPCKAITRILWLTTRQGLPFTIFQG 302
           DG+   W V S A   +P++++ P+G        P PCK I ++ + TTR G PF I  G
Sbjct: 258 DGTLTIWNVRSPA---KPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSG 314

Query: 303 GMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTE 340
           G+   + G R C++V+H       +    ++ F  L E
Sbjct: 315 GLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCE 352


>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
           sapiens]
          Length = 1115

 Score =  190 bits (483), Expect = 1e-48
 Identities = 111/338 (32%), Positives = 179/338 (52%), Gaps = 31/338 (9%)

Query: 12  VRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQ 71
           ++E L+ + FQ  KTV HGFP+QPSAL + P  +ILA+GT++GA++L+G PGVE    H 
Sbjct: 37  IQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHD 96

Query: 72  ENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQ 131
              AV Q+  L  +  LV+ L D++LHLW+L+ K  A  +     F             +
Sbjct: 97  SGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPA--ILHSLKFCRE----------R 144

Query: 132 ITVV-LPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEM 190
           +T   LP  S + LY+GTE GN+ +V + +F      T+S   ++     E   +     
Sbjct: 145 VTFCHLPFQS-KWLYVGTERGNIHIVNVESF------TLSGYVIMWNKAIELSSKSHPGP 197

Query: 191 VEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHS 250
           V  + ++P D  ++LIG+  G VV+WDL+  +  Y +   + + ++ W  +G+  +  HS
Sbjct: 198 VVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHS 257

Query: 251 DGSYCQWPVSSEAQQPEPLRSLVPYG--------PFPCKAITRILWLTTRQGLPFTIFQG 302
           DG+   W V S A   +P++++ P+G        P PCK I ++ + TTR G PF I  G
Sbjct: 258 DGTLTIWNVRSPA---KPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSG 314

Query: 303 GMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTE 340
           G+   + G R C++V+H       +    ++ F  L E
Sbjct: 315 GLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCE 352


>gi|149363700 syntaxin binding protein 5-like [Homo sapiens]
          Length = 1186

 Score =  170 bits (430), Expect = 2e-42
 Identities = 108/340 (31%), Positives = 168/340 (49%), Gaps = 31/340 (9%)

Query: 10  DPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGL 69
           + ++E L  + FQ  KTV HGFPHQP+AL + P  +ILAIGTR+GAI++ G PGV+    
Sbjct: 48  EEIQETLTSEYFQICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQ 107

Query: 70  HQENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSA 129
           H+   AV Q+  L  +  LV+   D++LHLW+L+ K  A  +     F          + 
Sbjct: 108 HESGAAVLQLQFLINEGALVSASSDDTLHLWNLRQKRPA--ILHSLKF----------NR 155

Query: 130 TQITVV-LPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVF 188
            +IT   LP  S + LY+GTE GN  +V + +F       +S   ++     E   +   
Sbjct: 156 ERITYCHLPFQS-KWLYVGTERGNTHIVNIESF------ILSGYVIMWNKAIELSTKTHP 208

Query: 189 EMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSC 248
             V  L + PRD  ++LIGY  G VV WDL+  R        + + +I W  +G+  +  
Sbjct: 209 GPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAIHSIDWHHEGKQFMCS 268

Query: 249 HSDGSYCQWPVSSEAQQPEPLRSLVPYGPF--------PCKAITRILWLTTRQGLPFTIF 300
           HSDGS   W + S ++   P ++ +P+G           CK I ++ + T +   PF IF
Sbjct: 269 HSDGSLTLWNLKSPSR---PFQTTIPHGKSQREGRKSESCKPILKVEYKTCKNSEPFIIF 325

Query: 301 QGGMPRASYGDRHCISVIHDGQQTAFDFTSRVIGFTVLTE 340
            GG+       R  ++++H    T  +    ++ F  L E
Sbjct: 326 SGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCE 365


>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
          Length = 400

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 47/272 (17%)

Query: 12  VRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQ 71
           VR  LKRD  Q+  +V H  P   S + ++P  R L+IG  +G I        EF+ L +
Sbjct: 48  VRVWLKRDSGQYWPSVYHAMPSPCSCMSFNPETRRLSIGLDNGTIS-------EFI-LSE 99

Query: 72  ENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQE-------DESFTLRG--P 122
           + N +T +         VT++      L+ L+++   S  Q+        ES    G   
Sbjct: 100 DYNKMTPVKNYQAHQSRVTMI------LFVLELEWVLSTGQDKQFAWHCSESGQRLGGYR 153

Query: 123 PGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEA 182
             A  S  Q  V   H     +++G  SG V +++L      E+ T+ +           
Sbjct: 154 TSAVASGLQFDVETRH-----VFIGDHSGQVTILKLEQ----ENCTLVT----------- 193

Query: 183 RHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLS--SQQLENIWWQR 240
             R     V AL   P     +  G S   V++WD+ G +     L   + +++ + + +
Sbjct: 194 TFRGHTGGVTALCWDPVQ-RVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQ 252

Query: 241 DGRLLVSCHSDGSYCQWPVSSEAQQ-PEPLRS 271
             R L+SC  DG    W +  E Q+ PE L S
Sbjct: 253 HTRQLISCGGDGGIVVWNMDVERQETPEWLDS 284


>gi|94400919 WD repeat domain 90 [Homo sapiens]
          Length = 1748

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 31   FPHQPS--ALGYSPSLRILA-IGTRSG-AIKLYGAPGVEFMGLHQENNAVTQIHLLPGQC 86
            FPH  +  AL +SP  R+L  +G   G  + L+G    + +   +    V  +   P   
Sbjct: 1203 FPHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEPVHGVAFNPWDA 1262

Query: 87   QLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYL 146
              +T +   ++  W L+ +G    LQ       R P   A  A ++T  L + +  LLY 
Sbjct: 1263 GELTCVGQGTVTFWLLQQRGADISLQ-----VRREPVPEAVGAGELTS-LCYGAPPLLYC 1316

Query: 147  GTESGNVFV 155
            GT SG V V
Sbjct: 1317 GTSSGQVCV 1325


>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
          Length = 434

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 45/219 (20%), Positives = 80/219 (36%), Gaps = 16/219 (7%)

Query: 40  YSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLLPGQCQLVTLLDDNSLHL 99
           + P   +L  GT  G   ++  P  +       N   T   +LP   + V   +D ++ +
Sbjct: 182 WHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRI 241

Query: 100 WSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHS-SCELLYLGTESGNVFVVQL 158
           W LK       L+  E    +GP     +    +++L  S  C+   +   +G V  V  
Sbjct: 242 WDLKQGSPIHVLKGTEGH--QGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFR 299

Query: 159 PAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDL 218
           P        T++S   L    E   +      VE+L      P    +GY  G + I+DL
Sbjct: 300 P-------ETVASQPSLGEGEESESN-----SVESLGFCSVMP-LAAVGYLDGTLAIYDL 346

Query: 219 QGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQW 257
               + +       +  + W+    ++ +C  DG    W
Sbjct: 347 ATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLW 385


>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
           sapiens]
          Length = 621

 Score = 35.4 bits (80), Expect = 0.079
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LG+ P+   LA+G  S  +++      E   LH   + V  
Sbjct: 495 DLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLS 554

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 555 LKFASCGRWFVSTGKDNLLNAW--RTPYGASIFQSKES 590


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score = 35.4 bits (80), Expect = 0.079
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LG+ P+   LA+G  S  +++      E   LH   + V  
Sbjct: 617 DLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLS 676

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 677 LKFASCGRWFVSTGKDNLLNAW--RTPYGASIFQSKES 712


>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
          Length = 770

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  S  +++      +   LH   + V  
Sbjct: 644 DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLS 703

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 704 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKES 739


>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
          Length = 538

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 204 ILIGYSRGLVVIWDLQGSRVLYHFLSSQ--QLENIWWQRDGRLLVSCHSDGSYCQWPVSS 261
           + +G + G +VIWD   +R +   +S+    + ++ W RDG  LVS  +D    QW V S
Sbjct: 39  LAVGCNDGRIVIWDFL-TRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLS 97


>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
          Length = 773

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  +  +++      +   LH   + V  
Sbjct: 647 DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLS 706

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 707 LKFAHCGKWFVSTGKDNLLNAW--RTPYGASIFQSKES 742


>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
           sapiens]
          Length = 769

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  S  +++      +   LH   + V  
Sbjct: 643 DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS 702

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 703 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKES 738


>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
           sapiens]
          Length = 760

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  S  +++      +   LH   + V  
Sbjct: 634 DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS 693

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 694 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKES 729


>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
           sapiens]
          Length = 772

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 19  DLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHQENNAVTQ 78
           DL +  +  +H F  Q  +LGY P+   LA+G  S  +++      +   LH   + V  
Sbjct: 646 DLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHHTKPDKYQLHLHESCVLS 705

Query: 79  IHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDES 116
           +         V+   DN L+ W  +   GAS  Q  ES
Sbjct: 706 LKFAYCGKWFVSTGKDNLLNAW--RTPYGASIFQSKES 741


>gi|188219762 denticleless homolog [Homo sapiens]
          Length = 730

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 28  EHGFPHQPSALGYS--PSLR-ILAIGTRSGAIKLYGAPGVEFMGLHQEN-----NAVTQI 79
           E G P  P    +S  P++  +LA+    G ++LY      F     +      NAV  +
Sbjct: 45  ETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDL 104

Query: 80  HLLPGQCQLVTLLDDNSLHLWSLK 103
             +PG+ +LVT   D +   W +K
Sbjct: 105 AWVPGELKLVTAAGDQTAKFWDVK 128


>gi|38605733 nucleoporin 43kDa [Homo sapiens]
          Length = 380

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 18/84 (21%), Positives = 35/84 (41%), Gaps = 7/84 (8%)

Query: 191 VEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQ-----RDGRLL 245
           +  +  HP   + +  G   G++ IWD++   +    L + + E   W+      +   L
Sbjct: 220 LHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAE--MWEVHFHPSNPEHL 277

Query: 246 VSCHSDGSYCQWPVSSEAQQPEPL 269
            +C  DGS   W  S++  +   L
Sbjct: 278 FTCSEDGSLWHWDASTDVPEKSSL 301


>gi|195972805 myocyte enhancer factor 2A isoform 4 [Homo sapiens]
          Length = 429

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 109 SELQEDESFTL-RGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDR 167
           S+L ED  F   RGPPG  P    ++V +P +S   L       ++    L A   L D 
Sbjct: 48  SKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDS 107

Query: 168 TISSDAVLQRLPEEARHRRV 187
           ++ S       P+   HR V
Sbjct: 108 SMLSP------PQTTLHRNV 121


>gi|195972803 myocyte enhancer factor 2A isoform 3 [Homo sapiens]
          Length = 437

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 109 SELQEDESFTL-RGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDR 167
           S+L ED  F   RGPPG  P    ++V +P +S   L       ++    L A   L D 
Sbjct: 48  SKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDS 107

Query: 168 TISSDAVLQRLPEEARHRRV 187
           ++ S       P+   HR V
Sbjct: 108 SMLSP------PQTTLHRNV 121


>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
          Length = 497

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 109 SELQEDESFTL-RGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDR 167
           S+L ED  F   RGPPG  P    ++V +P +S   L       ++    L A   L D 
Sbjct: 116 SKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDS 175

Query: 168 TISSDAVLQRLPEEARHRRV 187
           ++ S       P+   HR V
Sbjct: 176 SMLSP------PQTTLHRNV 189


>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
          Length = 410

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 5/77 (6%)

Query: 200 DPNQILI--GYSRGLVVIWDLQG--SRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYC 255
           DP Q L+  G S   +++WD+ G   R L       +++++ + +  R LVSC SDG   
Sbjct: 208 DPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIA 267

Query: 256 QWPVS-SEAQQPEPLRS 271
            W +  S  + P+ L S
Sbjct: 268 VWNMDVSREEAPQWLES 284


>gi|14150171 THO complex 3 [Homo sapiens]
          Length = 351

 Score = 32.7 bits (73), Expect = 0.51
 Identities = 18/75 (24%), Positives = 36/75 (48%)

Query: 177 RLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENI 236
           RL +E  +R   + V+ L  HP +P+  +       + IWD++ ++ +    +  +  NI
Sbjct: 88  RLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINI 147

Query: 237 WWQRDGRLLVSCHSD 251
            W  DG+ +   + D
Sbjct: 148 CWSPDGQTIAVGNKD 162


>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
          Length = 1170

 Score = 32.0 bits (71), Expect = 0.87
 Identities = 15/53 (28%), Positives = 28/53 (52%)

Query: 200 DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDG 252
           D  +I I Y  G V++  + G+R+    L   QL ++ W  D ++L+   ++G
Sbjct: 126 DGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSHVTWSADSKVLLFGMANG 178


>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
          Length = 1181

 Score = 32.0 bits (71), Expect = 0.87
 Identities = 15/53 (28%), Positives = 28/53 (52%)

Query: 200 DPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDG 252
           D  +I I Y  G V++  + G+R+    L   QL ++ W  D ++L+   ++G
Sbjct: 126 DGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSHVTWSADSKVLLFGMANG 178


>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
          Length = 489

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 13/119 (10%)

Query: 137 PHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQE 196
           PH+  E++  G+E   V V Q+P      +  ++S      +  E   +RV      +  
Sbjct: 92  PHND-EVIASGSEDCTVMVWQIP------ENGLTSPLTEPVVVLEGHTKRV----GIIAW 140

Query: 197 HPRDPNQILIGYSRGLVVIWDLQGSRVLYHF--LSSQQLENIWWQRDGRLLVSCHSDGS 253
           HP   N +L      +V+IW++  +  LY    L    + N+ W  +G L  S   D S
Sbjct: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKS 199


>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
          Length = 489

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 13/119 (10%)

Query: 137 PHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQE 196
           PH+  E++  G+E   V V Q+P      +  ++S      +  E   +RV      +  
Sbjct: 92  PHND-EVIASGSEDCTVMVWQIP------ENGLTSPLTEPVVVLEGHTKRV----GIIAW 140

Query: 197 HPRDPNQILIGYSRGLVVIWDLQGSRVLYHF--LSSQQLENIWWQRDGRLLVSCHSDGS 253
           HP   N +L      +V+IW++  +  LY    L    + N+ W  +G L  S   D S
Sbjct: 141 HPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKS 199


>gi|221219004 WD repeat domain 74 [Homo sapiens]
          Length = 385

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 34/133 (25%), Positives = 52/133 (39%), Gaps = 26/133 (19%)

Query: 165 EDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVL 224
           +D+  SSD +L+         RV   V  +++ P  P+ +  G     + IWDLQGS   
Sbjct: 115 KDKDTSSDPLLEL--------RVGPGVCRMRQDPAHPHVVATGGKENALKIWDLQGSE-- 164

Query: 225 YHFLSSQQLENIW-------WQRD------GRLLVSCHSDGSYCQWPVSSEAQQPEPLRS 271
                ++ + N W       W +D       + LV+C     Y Q  V   A        
Sbjct: 165 EPVFRAKNVRNDWLDLRVPIWDQDIQFLPGSQKLVTC---TGYHQVRVYDPASPQRRPVL 221

Query: 272 LVPYGPFPCKAIT 284
              YG +P  A+T
Sbjct: 222 ETTYGEYPLTAMT 234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,197,720
Number of Sequences: 37866
Number of extensions: 729917
Number of successful extensions: 1828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 1769
Number of HSP's gapped (non-prelim): 119
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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