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Search of human proteins with 62241033
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
(388 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 801 0.0
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 785 0.0
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 568 e-162
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 181 8e-46
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 179 4e-45
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 177 1e-44
gi|115387114 islet-1 [Homo sapiens] 176 2e-44
gi|50083287 LIM homeobox 8 [Homo sapiens] 174 9e-44
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 162 6e-40
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 161 8e-40
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 152 5e-37
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 144 2e-34
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 130 2e-30
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 130 2e-30
gi|21361802 LIM domain only 3 [Homo sapiens] 127 1e-29
gi|47778935 LIM domain only 3 [Homo sapiens] 127 1e-29
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 124 1e-28
gi|4505005 LIM domain only 1 [Homo sapiens] 124 2e-28
gi|5803072 LIM domain only 4 [Homo sapiens] 122 4e-28
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 97 3e-20
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 94 2e-19
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 94 2e-19
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 94 2e-19
gi|4505001 LIM domain kinase 1 [Homo sapiens] 89 9e-18
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 84 2e-16
gi|194272207 actin binding LIM protein family, member 2 isoform ... 80 3e-15
gi|153792514 actin binding LIM protein family, member 2 isoform ... 80 3e-15
gi|194272204 actin binding LIM protein family, member 2 isoform ... 80 3e-15
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 801 bits (2070), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 1 MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPA 60
MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPA
Sbjct: 1 MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPA 60
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS
Sbjct: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET
Sbjct: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
Query: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 240
LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN
Sbjct: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 240
Query: 241 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 300
EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR
Sbjct: 241 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 300
Query: 301 VLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPT 360
VLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPT
Sbjct: 301 VLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPT 360
Query: 361 ITVVTSVTSNMDSHESGSPSQTTLTNLF 388
ITVVTSVTSNMDSHESGSPSQTTLTNLF
Sbjct: 361 ITVVTSVTSNMDSHESGSPSQTTLTNLF 388
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 785 bits (2026), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 10 AMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKI 69
AMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKI
Sbjct: 19 AMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKI 78
Query: 70 SDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHL 129
SDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHL
Sbjct: 79 SDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHL 138
Query: 130 GISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ 189
GISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ
Sbjct: 139 GISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ 198
Query: 190 LSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQ 249
LSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQ
Sbjct: 199 LSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQ 258
Query: 250 QPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNA 309
QPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNA
Sbjct: 259 QPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNA 318
Query: 310 RAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTS 369
RAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTS
Sbjct: 319 RAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTS 378
Query: 370 NMDSHESGSPSQTTLTNLF 388
NMDSHESGSPSQTTLTNLF
Sbjct: 379 NMDSHESGSPSQTTLTNLF 397
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 568 bits (1463), Expect = e-162
Identities = 286/407 (70%), Positives = 326/407 (80%), Gaps = 30/407 (7%)
Query: 11 MLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAGMPPLSPEKPALCAGCGGKI 69
MLFH +SG + G+++EM+RR+K+EA A G + MP +S ++ ALCAGCGGKI
Sbjct: 1 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI 60
Query: 70 SDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHL 129
SDRYYLLAVDKQWH+RCLKCCECKL LESELTCF+KDGSIYCKEDYYRRFSVQRCARCHL
Sbjct: 61 SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL 120
Query: 130 GISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ 189
GISASEMVMRARD VYHL+CFTC+TCNK LTTGDHFGMKDSLVYCR HFE LLQGEYP
Sbjct: 121 GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH 180
Query: 190 LSYTEL--------AAKSGG--------LALPYFNGTGTVQKGRPRKRKSPALGVDIVNY 233
++ ++ AAKS G L LPY+NG GTVQKGRPRKRKSP G D+ Y
Sbjct: 181 FNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY 240
Query: 234 NS--GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 291
N+ CNEN+A+HLDRD QPYP SQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
Sbjct: 241 NAALSCNENDAEHLDRD-QPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 299
Query: 292 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSL----PAPPSAD--SGALT 345
AQKTGLTKRVLQVWFQNARAKFRRNLLRQEN GVDK+ +L P+ P+++ + +L+
Sbjct: 300 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLS 359
Query: 346 PPGTATTLTDLTNPTI----TVVTSVTSNMDSHESGSPSQTTLTNLF 388
P T TTLTDLT+PT+ +V+TSV N++ HE SPSQTTLTNLF
Sbjct: 360 PSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF 406
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 181 bits (460), Expect = 8e-46
Identities = 104/283 (36%), Positives = 155/283 (54%), Gaps = 37/283 (13%)
Query: 55 SPEKP--ALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC 111
S +KP A+C GCG +I D++ L ++ D +WH CLKC EC L+ TCF +DG YC
Sbjct: 18 SKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYC 77
Query: 112 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL 171
K DY R F + +CA+C +G S+S++VMRARDSVYH+ CF CS C++ L GD F +++
Sbjct: 78 KRDYVRLFGI-KCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHE 136
Query: 172 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV 231
+ CRA LL+ A +G P G + R G+ +
Sbjct: 137 LLCRADHGLLLE------------RAAAGSPRSP-----GPLPGAR---------GLHLP 170
Query: 232 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL 291
+ SG H+ + ++KT R+RT QL T+++ +A N PDA +QL
Sbjct: 171 DAGSGRQPALRPHVHKQ------TEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQL 224
Query: 292 AQKTGLTKRVLQVWFQNARAK-FRRNLLRQENGGVDKADGTSL 333
+ TGL+ RV++VWFQN R K ++++L ++ +D TSL
Sbjct: 225 VEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSL 267
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 179 bits (454), Expect = 4e-45
Identities = 104/316 (32%), Positives = 164/316 (51%), Gaps = 62/316 (19%)
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
+C+ CG +I DRY L + WH+RCL+C C+ +L + +C+ K+ I+CK DY+ RF
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
+CARC I AS+ V RAR + YHL+CF C +C + L+TG+ FG+ + V CR H++T
Sbjct: 158 T-KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
Query: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 240
+++ + AA+ NG G +G
Sbjct: 217 MIEN--------LKRAAE---------NGNGLTLEG------------------------ 235
Query: 241 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 300
A ++D QP P KR RTSF QL+ M++ FA ++NPDA+ L++LA TGL++R
Sbjct: 236 -AVPSEQDSQPKP----AKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
Query: 301 VLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTL--TDLTN 358
V+QVWFQN RA+ +++ + P PPS + P + + T ++
Sbjct: 291 VIQVWFQNCRARHKKHTPQH-------------PVPPSGAPPSRLPSALSDDIHYTPFSS 337
Query: 359 PTITVVTSVTSNMDSH 374
P + ++ ++SH
Sbjct: 338 PERARMVTLHGYIESH 353
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 177 bits (450), Expect = 1e-44
Identities = 95/256 (37%), Positives = 144/256 (56%), Gaps = 47/256 (18%)
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
+C+ CG +I DRY L + WH+RCL+C C+ +L + +C+ K+ I+CK DY+ RF
Sbjct: 98 ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFG 157
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
+CARC I AS+ V RAR + YHL+CF C +C + L+TG+ FG+ + V CR H++T
Sbjct: 158 T-KCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
Query: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNEN 240
+++ + AA+ NG G +G
Sbjct: 217 MIEN--------LKRAAE---------NGNGLTLEG------------------------ 235
Query: 241 EADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKR 300
A ++D QP P KR RTSF QL+ M++ FA ++NPDA+ L++LA TGL++R
Sbjct: 236 -AVPSEQDSQPKP----AKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRR 290
Query: 301 VLQVWFQNARAKFRRN 316
V+QVWFQN RA+ +++
Sbjct: 291 VIQVWFQNCRARHKKH 306
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 176 bits (447), Expect = 2e-44
Identities = 96/270 (35%), Positives = 140/270 (51%), Gaps = 36/270 (13%)
Query: 48 DAGMPPLSPEKPALCAGCGGKISDRYYL-LAVDKQWHLRCLKCCECKLALESELTCFAKD 106
D G PP +LC GCG +I D+Y L ++ D +WH CLKC EC L+ TCF +D
Sbjct: 3 DMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRD 62
Query: 107 GSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG 166
G YCK DY R + + +CA+C +G S ++ VMRAR VYH+ CF C C++ L GD F
Sbjct: 63 GKTYCKRDYIRLYGI-KCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFA 121
Query: 167 MKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQ-KGRPRKRKSPA 225
+++ ++CRA + + E A+ G L + +Q P + PA
Sbjct: 122 LREDGLFCRADHDVV------------ERASLGAGDPLSPLHPARPLQMAAEPISARQPA 169
Query: 226 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA 285
L + +QP +KT R+RT QL T+++ +A N PDA
Sbjct: 170 LRPHV-----------------HKQP----EKTTRVRTVLNEKQLHTLRTCYAANPRPDA 208
Query: 286 KDLKQLAQKTGLTKRVLQVWFQNARAKFRR 315
+QL + TGL+ RV++VWFQN R K ++
Sbjct: 209 LMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 174 bits (442), Expect = 9e-44
Identities = 111/331 (33%), Positives = 169/331 (51%), Gaps = 63/331 (19%)
Query: 56 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDY 115
P +C CG +I D+Y L D WH+RCL C C+ +L +C+ KD I+CK DY
Sbjct: 69 PPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDY 128
Query: 116 YRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCR 175
+RR+ RC+RC I +++ V RA+ +VYHL+CF C +C + L+TG+ F + + V CR
Sbjct: 129 FRRYGT-RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCR 187
Query: 176 AHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 235
H++ +L L NG G +G +
Sbjct: 188 VHYDCMLD-----------------NLKREVENGNGISVEG------------------A 212
Query: 236 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 295
E + +H P P KR RTSF QL+ M++ FA ++NPDA+ L++LA++T
Sbjct: 213 LLTEQDVNH------PKP----AKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERT 262
Query: 296 GLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPA-PPSADSGALTPPGTATTLT 354
GL++RV+QVWFQN RA+ ++++ + + T + A PPS L+PP
Sbjct: 263 GLSRRVIQVWFQNCRARHKKHV------SPNHSSSTPVTAVPPS----RLSPPMLEEMAY 312
Query: 355 DLTNPTI-TVVTSVTSNMDSHESGSPSQTTL 384
P T++T++ S MD+H S TTL
Sbjct: 313 SAYVPQDGTMLTALHSYMDAH-----SPTTL 338
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 162 bits (409), Expect = 6e-40
Identities = 96/256 (37%), Positives = 140/256 (54%), Gaps = 25/256 (9%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGC I DR+ L +D+ WH++C++CCECK L + CF+++G +YCK D++RRF
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEK--CFSREGKLYCKNDFFRRFGT 62
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH-FGMKDSLVYCRAHFET 180
+CA C GIS S++V +AR V+HL+CFTC CNK L+TG+ + + ++ C+ +
Sbjct: 63 -KCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDY-- 119
Query: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNY-NSGCNE 239
LS + L K G L N + AL D NS ++
Sbjct: 120 ---------LSSSSL--KEGSL-----NSVSSCTDRSLSPDLQDALQDDPKETDNSTSSD 163
Query: 240 NEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTK 299
E + + ++Q K + RT+ K QL T+K+ FA P +QLAQ+TGL
Sbjct: 164 KETANNENEEQ--NSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNM 221
Query: 300 RVLQVWFQNARAKFRR 315
RV+QVWFQN R+K RR
Sbjct: 222 RVIQVWFQNRRSKERR 237
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 161 bits (408), Expect = 8e-40
Identities = 95/258 (36%), Positives = 138/258 (53%), Gaps = 28/258 (10%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGC I DR+ L +D+ WH++C++CCECK L + CF+++G +YCK D++R F
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEK--CFSREGKLYCKNDFFRCFGT 61
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY-CRAHFET 180
+CA C GIS S++V RAR V+HL+CFTC CNK L+TG+ + D + C+ +
Sbjct: 62 -KCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDY-- 118
Query: 181 LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYN---SGC 237
LS + + AK L ++ + A + N + +G
Sbjct: 119 ---------LSNSSV-AKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGS 168
Query: 238 NENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGL 297
NEN+ +L K + RT+ K QL T+K+ FA P +QLAQ+TGL
Sbjct: 169 NENDDQNL---------GAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGL 219
Query: 298 TKRVLQVWFQNARAKFRR 315
RV+QVWFQN R+K RR
Sbjct: 220 NMRVIQVWFQNRRSKERR 237
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 152 bits (384), Expect = 5e-37
Identities = 102/324 (31%), Positives = 148/324 (45%), Gaps = 38/324 (11%)
Query: 60 ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRF 119
++C GC I DR+ L D WH +C++C CK LE+ TCF +D +YCK DY + F
Sbjct: 33 SVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLET--TCFYRDKKLYCKYDYEKLF 90
Query: 120 SVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE 179
+V +C C I+ +E VMRA+ SVYHLSCF C C + L GD F +K+ + C+ +E
Sbjct: 91 AV-KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
Query: 180 TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNE 239
+ LS AA G + +L G E
Sbjct: 150 KERE-----LLSLVSPAASDSG-----------------KSDDEESLCKSAHGAGKGTAE 187
Query: 240 NEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTK 299
DH ++ KR RT Q R K+ F ++ P K + LA +TGL+
Sbjct: 188 EGKDH-----------KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV 236
Query: 300 RVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNP 359
RV+QVWFQN RAK ++ RQ+ D+ + L + + G+ G T L P
Sbjct: 237 RVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTP 296
Query: 360 --TITVVTSVTSNMDSHESGSPSQ 381
+ + SV S+ + +P Q
Sbjct: 297 QQLLAIEQSVYSSDPFRQGLTPPQ 320
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 144 bits (362), Expect = 2e-34
Identities = 85/266 (31%), Positives = 127/266 (47%), Gaps = 39/266 (14%)
Query: 59 PALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRR 118
PA+C GC ISDR+ + + WH CL+C C+ AL + +C+ +D +YCK+DY +
Sbjct: 30 PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTT--SCYFRDRKLYCKQDYQQL 87
Query: 119 FSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHF 178
F+ +C+ C I+ +E VMRA + VYHL CF C C + L GD F +K+ + C+ +
Sbjct: 88 FAA-KCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDY 146
Query: 179 ET---LLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 235
E LL P + + + G + G G+ KG K P
Sbjct: 147 EKEKDLLSSVSPDESDSVKSEDEDGDMKPA--KGQGSQSKGSGDDGKDP----------- 193
Query: 236 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 295
++ KR RT Q R K+ F ++ P K + LA +T
Sbjct: 194 --------------------RRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAET 233
Query: 296 GLTKRVLQVWFQNARAKFRRNLLRQE 321
GL+ RV+QVWFQN RAK ++ R +
Sbjct: 234 GLSVRVVQVWFQNQRAKMKKLARRHQ 259
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 179
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 88 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
Query: 180 TLLQGE 185
T Q E
Sbjct: 147 TAKQRE 152
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 22/199 (11%)
Query: 124 CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE---- 179
CA C I +++A D +H C CS C+ L + + VYC+ F
Sbjct: 31 CAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDDFFKRFG 87
Query: 180 ---TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSG 236
Q PP T++ ++ V K + A G +
Sbjct: 88 TKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEFYLMEDS 137
Query: 237 CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTG 296
+AD+ Q+ + KR RT+ QL T+KS + + P +QL+ +TG
Sbjct: 138 RLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETG 195
Query: 297 LTKRVLQVWFQNARAKFRR 315
L RV+QVWFQN RAK +R
Sbjct: 196 LDMRVVQVWFQNRRAKEKR 214
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 179
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 93 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 151
Query: 180 TLLQGE 185
T Q E
Sbjct: 152 TAKQRE 157
Score = 55.8 bits (133), Expect = 6e-08
Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 22/205 (10%)
Query: 118 RFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAH 177
R + CA C I +++A D +H C CS C+ L + + VYC+
Sbjct: 30 RREIPLCAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDD 86
Query: 178 FE-------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDI 230
F Q PP T++ ++ V K + A G +
Sbjct: 87 FFKRFGTKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEF 136
Query: 231 VNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 290
+AD+ Q+ + KR RT+ QL T+KS + + P +Q
Sbjct: 137 YLMEDSRLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQ 194
Query: 291 LAQKTGLTKRVLQVWFQNARAKFRR 315
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 195 LSSETGLDMRVVQVWFQNRRAKEKR 219
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 127 bits (320), Expect = 1e-29
Identities = 65/137 (47%), Positives = 83/137 (60%), Gaps = 5/137 (3%)
Query: 58 KPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKEDY 115
KP CAGC KI DRY L A+DK WH CLKC C+C+L E T + K I C+ DY
Sbjct: 9 KPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLG-EVGSTLYTKANLILCRRDY 67
Query: 116 YRRFSVQ-RCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYC 174
R F V CA C I A EMVMRA+D+VYHL CF C CN+ GD F +K++++ C
Sbjct: 68 LRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILC 127
Query: 175 RAHFET-LLQGEYPPQL 190
+ +E L++ Y PQ+
Sbjct: 128 QTDYEEGLMKEGYAPQV 144
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 127 bits (320), Expect = 1e-29
Identities = 65/137 (47%), Positives = 83/137 (60%), Gaps = 5/137 (3%)
Query: 58 KPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKEDY 115
KP CAGC KI DRY L A+DK WH CLKC C+C+L E T + K I C+ DY
Sbjct: 9 KPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLG-EVGSTLYTKANLILCRRDY 67
Query: 116 YRRFSVQ-RCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYC 174
R F V CA C I A EMVMRA+D+VYHL CF C CN+ GD F +K++++ C
Sbjct: 68 LRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILC 127
Query: 175 RAHFET-LLQGEYPPQL 190
+ +E L++ Y PQ+
Sbjct: 128 QTDYEEGLMKEGYAPQV 144
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 124 bits (312), Expect = 1e-28
Identities = 54/125 (43%), Positives = 79/125 (63%), Gaps = 4/125 (3%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGC I D++ L +D+ WH CLKC +C++ L CF++ GS+YCKED+++RF
Sbjct: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFET 180
+C C GI +++V +A+D VYHL CF C CN+ L TGD F M+D + C+ +ET
Sbjct: 88 -KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYET 146
Query: 181 LLQGE 185
Q +
Sbjct: 147 AKQND 151
Score = 57.8 bits (138), Expect = 2e-08
Identities = 54/205 (26%), Positives = 82/205 (40%), Gaps = 27/205 (13%)
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE- 179
+ +CA C+ I + +++ D +H SC C+ C L D + VYC+ F
Sbjct: 27 IPQCAGCNQHI-LDKFILKVLDRHWHSSCLKCADCQMQLA--DRCFSRAGSVYCKEDFFK 83
Query: 180 ------TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNY 233
T Q PP T++ K+ + + A G +
Sbjct: 84 RFGTKCTACQQGIPP----TQVVRKAQDFVYHLHCFACIICN------RQLATGDEFYLM 133
Query: 234 NSG---CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQ 290
G C E+ D KR RT+ QL T+K+ + + P +Q
Sbjct: 134 EDGRLVCKEDYETAKQNDDS----EAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQ 189
Query: 291 LAQKTGLTKRVLQVWFQNARAKFRR 315
L+ +TGL RV+QVWFQN RAK +R
Sbjct: 190 LSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 124 bits (310), Expect = 2e-28
Identities = 67/151 (44%), Positives = 87/151 (57%), Gaps = 8/151 (5%)
Query: 47 RDAGMPPLSPE---KPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELT 101
++ G+P LS + K CAGC KI DRY L A+DK WH CLKC C+C+L E T
Sbjct: 6 KEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLG-EVGST 64
Query: 102 CFAKDGSIYCKEDYYRRFSVQ-RCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLT 160
+ K I C+ DY R F CA C I A EMVMRARD+VYHL CF C CN+
Sbjct: 65 LYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFC 124
Query: 161 TGDHFGMKDSLVYCRAHFET-LLQGEYPPQL 190
GD F +K++++ C+ +E L G + Q+
Sbjct: 125 VGDKFFLKNNMILCQMDYEEGQLNGTFESQV 155
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 122 bits (307), Expect = 4e-28
Identities = 59/123 (47%), Positives = 74/123 (60%), Gaps = 2/123 (1%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLAL-ESELTCFAKDGSIYCKEDYYRRFS 120
CAGCGGKI+DR+ L A+D WH RCLKC C+ L + +C+ K G I C+ DY R F
Sbjct: 23 CAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFG 82
Query: 121 VQ-RCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE 179
C+ C I ASE+VMRA+ +VYHL CFTCSTC L GD F + ++C
Sbjct: 83 NSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHDRP 142
Query: 180 TLL 182
T L
Sbjct: 143 TAL 145
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 50/122 (40%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
P C GC I DRY+L A+D+ WH CL C C C+L E + K G C+
Sbjct: 24 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLG-EVGRRLYYKLGRKLCRR 82
Query: 114 DYYRRFSVQR-CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R F CA C I A EM MR +D VYHL CF C+ C K GD + + +S +
Sbjct: 83 DYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDI 142
Query: 173 YC 174
C
Sbjct: 143 VC 144
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 50/122 (40%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
P C GC I DRY+L A+D+ WH CL C C C+L E + K G C+
Sbjct: 24 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLG-EVGRRLYYKLGRKLCRR 82
Query: 114 DYYRRFSVQR-CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R F CA C I A EM MR +D VYHL CF C+ C K GD + + +S +
Sbjct: 83 DYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDI 142
Query: 173 YC 174
C
Sbjct: 143 VC 144
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 96.7 bits (239), Expect = 3e-20
Identities = 50/122 (40%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 56 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
P C GC I DRY+L A+D+ WH CL C C C+L E + K G C+
Sbjct: 93 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLG-EVGRRLYYKLGRKLCRR 151
Query: 114 DYYRRFSVQR-CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R F CA C I A EM MR +D VYHL CF C+ C K GD + + +S +
Sbjct: 152 DYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDI 211
Query: 173 YC 174
C
Sbjct: 212 VC 213
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 94.4 bits (233), Expect = 2e-19
Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGCG I + LLA+DKQWHL C KC C L E +KDG+ YC++DY F V
Sbjct: 166 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY--ISKDGAPYCEKDYQGLFGV 223
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
+C CH I+ V+ A D YH SC CS CN+ T G+ ++ S V+
Sbjct: 224 -KCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVW 272
Score = 53.1 bits (126), Expect = 4e-07
Identities = 39/121 (32%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 57 EKPAL-CAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
EKP + C CG L K +H++C C C C LA F K+G C
Sbjct: 33 EKPVIHCHKCGEPCKGEV-LRVQTKHFHIKCFTCKVCGCDLAQGG---FFIKNGEYLCTL 88
Query: 114 DYYRRFSVQRCARCH-LGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH--FGMKDS 170
DY R + RCH G V+ A YH +CF C+ C + GD F +D
Sbjct: 89 DYQRMYGT----RCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 144
Query: 171 L 171
L
Sbjct: 145 L 145
Score = 33.1 bits (74), Expect = 0.44
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
V C +C G V+R + +H+ CFTC C L G F +K+ C ++
Sbjct: 36 VIHCHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF-IKNGEYLCTLDYQR 92
Query: 181 L 181
+
Sbjct: 93 M 93
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 94.4 bits (233), Expect = 2e-19
Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGCG I + LLA+DKQWHL C KC C L E +KDG+ YC++DY F V
Sbjct: 166 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY--ISKDGAPYCEKDYQGLFGV 223
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
+C CH I+ V+ A D YH SC CS CN+ T G+ ++ S V+
Sbjct: 224 -KCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVW 272
Score = 53.1 bits (126), Expect = 4e-07
Identities = 39/121 (32%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 57 EKPAL-CAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
EKP + C CG L K +H++C C C C LA F K+G C
Sbjct: 33 EKPVIHCHKCGEPCKGEV-LRVQTKHFHIKCFTCKVCGCDLAQGG---FFIKNGEYLCTL 88
Query: 114 DYYRRFSVQRCARCH-LGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH--FGMKDS 170
DY R + RCH G V+ A YH +CF C+ C + GD F +D
Sbjct: 89 DYQRMYGT----RCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 144
Query: 171 L 171
L
Sbjct: 145 L 145
Score = 33.1 bits (74), Expect = 0.44
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
V C +C G V+R + +H+ CFTC C L G F +K+ C ++
Sbjct: 36 VIHCHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF-IKNGEYLCTLDYQR 92
Query: 181 L 181
+
Sbjct: 93 M 93
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 94.4 bits (233), Expect = 2e-19
Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
CAGCG I + LLA+DKQWHL C KC C L E +KDG+ YC++DY F V
Sbjct: 226 CAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY--ISKDGAPYCEKDYQGLFGV 283
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
+C CH I+ V+ A D YH SC CS CN+ T G+ ++ S V+
Sbjct: 284 -KCEACHQFITGK--VLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVW 332
Score = 53.1 bits (126), Expect = 4e-07
Identities = 39/121 (32%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 57 EKPAL-CAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKE 113
EKP + C CG L K +H++C C C C LA F K+G C
Sbjct: 93 EKPVIHCHKCGEPCKGEV-LRVQTKHFHIKCFTCKVCGCDLAQGG---FFIKNGEYLCTL 148
Query: 114 DYYRRFSVQRCARCH-LGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDH--FGMKDS 170
DY R + RCH G V+ A YH +CF C+ C + GD F +D
Sbjct: 149 DYQRMYGT----RCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDC 204
Query: 171 L 171
L
Sbjct: 205 L 205
Score = 33.1 bits (74), Expect = 0.44
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFET 180
V C +C G V+R + +H+ CFTC C L G F +K+ C ++
Sbjct: 96 VIHCHKC--GEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF-IKNGEYLCTLDYQR 152
Query: 181 L 181
+
Sbjct: 153 M 153
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 88.6 bits (218), Expect = 9e-18
Identities = 43/124 (34%), Positives = 71/124 (57%), Gaps = 6/124 (4%)
Query: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
+CA CG +I D YL A++ WH C +CC+C +L + + KDG ++CK+DY+ R+
Sbjct: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQY--YEKDGQLFCKKDYWARYG 81
Query: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGM-KDSLVYC-RAHF 178
+ C C I+ +VM A + YH CF C TC + GD + + + S +YC ++
Sbjct: 82 -ESCHGCSEQITKG-LVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYY 139
Query: 179 ETLL 182
+T++
Sbjct: 140 QTVV 143
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/125 (36%), Positives = 64/125 (51%), Gaps = 5/125 (4%)
Query: 49 AGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGS 108
A P+ P+ CAGC +I LLA+DKQWH+ C KC C + L E +KDG
Sbjct: 138 ASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEY--ISKDGV 195
Query: 109 IYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMK 168
YC+ DY+ +F + +C C IS V+ A YH +C C C++ T G+ +
Sbjct: 196 PYCESDYHAQFGI-KCETCDRYISG--RVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLT 252
Query: 169 DSLVY 173
S V+
Sbjct: 253 GSEVW 257
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
Query: 79 DKQWHLRCLKC--CECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEM 136
+ +H+RC C C C LA F K+ C +DY + + RC C I+
Sbjct: 39 NNHFHIRCFTCQVCGCGLAQSG---FFFKNQEYICTQDYQQLYGT-RCDSCRDFITGE-- 92
Query: 137 VMRARDSVYHLSCFTCSTCNKTLTTGD 163
V+ A YH CF CS C K GD
Sbjct: 93 VISALGRTYHPKCFVCSLCRKPFPIGD 119
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 120 SVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE 179
+V +C RC G + V+R ++ +H+ CFTC C L F K+ C ++
Sbjct: 19 NVIQCYRC--GDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFF-FKNQEYICTQDYQ 75
Query: 180 TL 181
L
Sbjct: 76 QL 77
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 80.1 bits (196), Expect = 3e-15
Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
C GCG +I + L+A+DK WHL C KC C L +E +KDG YC+ DY+ +F +
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEY--ISKDGLPYCEADYHAKFGI 210
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
RC C I+ V+ A + YH SC C C + G+ ++ S ++
Sbjct: 211 -RCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
Score = 56.6 bits (135), Expect = 4e-08
Identities = 38/123 (30%), Positives = 47/123 (38%), Gaps = 9/123 (7%)
Query: 55 SPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCK 112
SP LC CG + L DK +H++C C C C LA E F + G C
Sbjct: 17 SPSTAILCNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLA---EGGFFVRQGEYICT 72
Query: 113 EDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R + RC C I V+ A YH CF C+ C GD
Sbjct: 73 LDYQRLYGT-RCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKEC 129
Query: 173 YCR 175
C+
Sbjct: 130 MCQ 132
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 15/59 (25%)
Query: 137 VMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTEL 195
V+R +D +H+ CF C C L G F + QGEY L Y L
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGGFF---------------VRQGEYICTLDYQRL 78
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 80.1 bits (196), Expect = 3e-15
Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
C GCG +I + L+A+DK WHL C KC C L +E +KDG YC+ DY+ +F +
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEY--ISKDGLPYCEADYHAKFGI 210
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
RC C I+ V+ A + YH SC C C + G+ ++ S ++
Sbjct: 211 -RCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
Score = 56.6 bits (135), Expect = 4e-08
Identities = 38/123 (30%), Positives = 47/123 (38%), Gaps = 9/123 (7%)
Query: 55 SPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCK 112
SP LC CG + L DK +H++C C C C LA E F + G C
Sbjct: 17 SPSTAILCNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLA---EGGFFVRQGEYICT 72
Query: 113 EDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R + RC C I V+ A YH CF C+ C GD
Sbjct: 73 LDYQRLYGT-RCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKEC 129
Query: 173 YCR 175
C+
Sbjct: 130 MCQ 132
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 15/59 (25%)
Query: 137 VMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTEL 195
V+R +D +H+ CF C C L G F + QGEY L Y L
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGGFF---------------VRQGEYICTLDYQRL 78
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 80.1 bits (196), Expect = 3e-15
Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 5/112 (4%)
Query: 62 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSV 121
C GCG +I + L+A+DK WHL C KC C L +E +KDG YC+ DY+ +F +
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEY--ISKDGLPYCEADYHAKFGI 210
Query: 122 QRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVY 173
RC C I+ V+ A + YH SC C C + G+ ++ S ++
Sbjct: 211 -RCDSCEKYITG--RVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
Score = 56.6 bits (135), Expect = 4e-08
Identities = 38/123 (30%), Positives = 47/123 (38%), Gaps = 9/123 (7%)
Query: 55 SPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKC--CECKLALESELTCFAKDGSIYCK 112
SP LC CG + L DK +H++C C C C LA E F + G C
Sbjct: 17 SPSTAILCNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLA---EGGFFVRQGEYICT 72
Query: 113 EDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLV 172
DY R + RC C I V+ A YH CF C+ C GD
Sbjct: 73 LDYQRLYGT-RCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKEC 129
Query: 173 YCR 175
C+
Sbjct: 130 MCQ 132
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 15/59 (25%)
Query: 137 VMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTEL 195
V+R +D +H+ CF C C L G F + QGEY L Y L
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGGFF---------------VRQGEYICTLDYQRL 78
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,295,859
Number of Sequences: 37866
Number of extensions: 794111
Number of successful extensions: 5110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 3880
Number of HSP's gapped (non-prelim): 1044
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.