Guide to the Human Genome
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Search of human proteins with 59710085

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|59710085 hypothetical protein LOC146562 [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|59710085 hypothetical protein LOC146562 [Homo sapiens]            1046   0.0  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    45   1e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    43   6e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    43   6e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    43   6e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    43   6e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    43   6e-04
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    43   6e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              42   0.001
gi|20070205 ladinin 1 [Homo sapiens]                                   42   0.002
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    40   0.005
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    40   0.005
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  39   0.015
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  39   0.015
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    39   0.015
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    37   0.033
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    37   0.033
gi|239747143 PREDICTED: hypothetical protein XP_002343924 [Homo ...    37   0.057
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         37   0.057
gi|157785645 SPEG complex locus [Homo sapiens]                         37   0.057
gi|109637771 calpastatin isoform l [Homo sapiens]                      36   0.075
gi|109637769 calpastatin isoform k [Homo sapiens]                      36   0.075
gi|109637767 calpastatin isoform j [Homo sapiens]                      36   0.075
gi|109637765 calpastatin isoform i [Homo sapiens]                      36   0.075
gi|109637763 calpastatin isoform h [Homo sapiens]                      36   0.075
gi|109637761 calpastatin isoform g [Homo sapiens]                      36   0.075
gi|109637759 calpastatin isoform f [Homo sapiens]                      36   0.075
gi|109637757 calpastatin isoform e [Homo sapiens]                      36   0.075
gi|27765085 calpastatin isoform b [Homo sapiens]                       36   0.075
gi|109637753 calpastatin isoform a [Homo sapiens]                      36   0.075

>gi|59710085 hypothetical protein LOC146562 [Homo sapiens]
          Length = 520

 Score = 1046 bits (2706), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MASNDKGMAPSLGSPWASQMGPWDAILKAVKDQLPSLDSDSPLSDYGEEELFIFQRNQTS 60
           MASNDKGMAPSLGSPWASQMGPWDAILKAVKDQLPSLDSDSPLSDYGEEELFIFQRNQTS
Sbjct: 1   MASNDKGMAPSLGSPWASQMGPWDAILKAVKDQLPSLDSDSPLSDYGEEELFIFQRNQTS 60

Query: 61  LIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEG 120
           LIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEG
Sbjct: 61  LIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEG 120

Query: 121 RDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGD 180
           RDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGD
Sbjct: 121 RDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGD 180

Query: 181 PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAES 240
           PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAES
Sbjct: 181 PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAES 240

Query: 241 APRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVWWAADHRQVQ 300
           APRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVWWAADHRQVQ
Sbjct: 241 APRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVWWAADHRQVQ 300

Query: 301 DRMVPSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGP 360
           DRMVPSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGP
Sbjct: 301 DRMVPSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGP 360

Query: 361 GPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGAS 420
           GPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGAS
Sbjct: 361 GPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGAS 420

Query: 421 PSSLGLRTCTGKSQLLQQLRAFQKGTAQPELPASKGPAGGRAQAPEDTAGSRTGRKQHMK 480
           PSSLGLRTCTGKSQLLQQLRAFQKGTAQPELPASKGPAGGRAQAPEDTAGSRTGRKQHMK
Sbjct: 421 PSSLGLRTCTGKSQLLQQLRAFQKGTAQPELPASKGPAGGRAQAPEDTAGSRTGRKQHMK 480

Query: 481 LCAKGQSAQARLPRGRPRALGDVPEPGAAREALMPPLEQL 520
           LCAKGQSAQARLPRGRPRALGDVPEPGAAREALMPPLEQL
Sbjct: 481 LCAKGQSAQARLPRGRPRALGDVPEPGAAREALMPPLEQL 520


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 77/386 (19%), Positives = 147/386 (38%), Gaps = 66/386 (17%)

Query: 66  SEELAEDPADGDKSRAWVAAAEESLPEPVLV---PAELATEPGCRQNTRTKDASSQEGRD 122
           S   +   +D  +     A  ++++P+  +V   P + AT P  R+++ ++D+SS E  +
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTP-TRKSSSSEDSSSDEEEE 277

Query: 123 PGRPFESS-GEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGDP 181
             +P ++  G  S++   +  PP+            + G+Q P    + +  +   E   
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPK-----------KSLGTQPPKKAVEKQQPVESSEDSS 326

Query: 182 KAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAESA 241
                S+  ++    +A+    +   +    +K    +   + SD     EAP   A + 
Sbjct: 327 DESDSSSEEEKKPPTKAVVS--KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTT 384

Query: 242 PRS--------KMPLVEPPEGP--PVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVW 291
             S        K P V+P   P  PV   Q+L     D    S + +E++  +    T  
Sbjct: 385 KNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKAD----SSSSEEESSSSEEEKT-- 438

Query: 292 WAADHRQVQDRMVPSAHNRLMEQLAL-LCTTQSKASACARKVPADTPQDTKEADSGSRCA 350
                     +MV +   +   + AL L   Q+   +      +D+    +E +  S+ A
Sbjct: 439 ---------KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSA 489

Query: 351 SRKQGSQAGPGP---QLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEE 407
            +K+  +   G    + A   +  AES                   S+S SS DS EEEE
Sbjct: 490 VKKKPQKVAGGAAPSKPASAKKGKAES-------------------SNSSSSDDSSEEEE 530

Query: 408 EEMAALGDAEGASPSSLGLRTCTGKS 433
           E++   G     +P + G    T ++
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQN 556


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 228 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 287

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 288 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 388

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 389 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 448

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 566

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 614

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 615 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 660

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 661 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 719

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 720 ARAPSAKGTISAPG 733



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 314

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 315 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 374

Query: 509 A 509
           A
Sbjct: 375 A 375


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 365 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 465

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 466 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 643

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 691

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 692 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 737

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 738 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 796

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 797 ARAPSAKGTISAPG 810



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 340 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 391

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 392 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451

Query: 509 A 509
           A
Sbjct: 452 A 452



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 17/122 (13%)

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGT----A 447
           PE  S SS +  E EEE  A       AS   L +R  +  +          KGT    A
Sbjct: 266 PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA----------KGTPGKGA 315

Query: 448 QPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPG 507
            P  P   G    + +A +    S +  ++      +  +A+A L   + +A G   + G
Sbjct: 316 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL---QAKASGKTSQVG 372

Query: 508 AA 509
           AA
Sbjct: 373 AA 374


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 365 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 465

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 466 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 643

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 691

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 692 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 737

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 738 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 796

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 797 ARAPSAKGTISAPG 810



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 340 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 391

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 392 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451

Query: 509 A 509
           A
Sbjct: 452 A 452



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 17/122 (13%)

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGT----A 447
           PE  S SS +  E EEE  A       AS   L +R  +  +          KGT    A
Sbjct: 266 PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA----------KGTPGKGA 315

Query: 448 QPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPG 507
            P  P   G    + +A +    S +  ++      +  +A+A L   + +A G   + G
Sbjct: 316 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL---QAKASGKTSQVG 372

Query: 508 AA 509
           AA
Sbjct: 373 AA 374


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 228 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 287

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 288 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 388

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 389 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 448

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 566

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 614

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 615 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 660

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 661 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 719

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 720 ARAPSAKGTISAPG 733



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 263 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 314

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 315 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 374

Query: 509 A 509
           A
Sbjct: 375 A 375


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 365 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 465

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 466 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 643

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 691

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 692 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 737

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 738 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 796

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 797 ARAPSAKGTISAPG 810



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 340 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 391

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 392 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451

Query: 509 A 509
           A
Sbjct: 452 A 452



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 17/122 (13%)

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGT----A 447
           PE  S SS +  E EEE  A       AS   L +R  +  +          KGT    A
Sbjct: 266 PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA----------KGTPGKGA 315

Query: 448 QPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPG 507
            P  P   G    + +A +    S +  ++      +  +A+A L   + +A G   + G
Sbjct: 316 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL---QAKASGKTSQVG 372

Query: 508 AA 509
           AA
Sbjct: 373 AA 374


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 117/554 (21%), Positives = 184/554 (33%), Gaps = 103/554 (18%)

Query: 9   APSLGSPWASQM----GPWDAILKAVKDQLPSLDSDSPLSDYGEEE---------LFIFQ 55
           AP+ G+P         G   A+    K   P  DS+S   +  + E         L    
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364

Query: 56  RNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDA 115
             +TS +   S    E P  G       A A      P +  A+        Q++  +  
Sbjct: 365 SGKTSQVGAASAPAKESPRKG------AAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 418

Query: 116 SSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLS 175
           S +E     +P   + +V A    A+E PR             KG+   P      A   
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPAKESPR-------------KGAAPAPPRKTGPAAAQ 465

Query: 176 CHEGDPKAEPLSTASQESVNRRALRQERRKMIE----TDILQKVTRDACGPTSSDKGGVK 231
              G  + +  S++ +   +R AL       ++    +  ++  +    GP     G V 
Sbjct: 466 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525

Query: 232 EAPCHAA----------ESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDN 281
                 A          E +  S     +  +G    ++   +   L +ILQ+       
Sbjct: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585

Query: 282 QG---NRAPGTVWWAA----DHRQVQDRMVPSAHNRLMEQLALLCTTQSKAS-------A 327
           +G      P  V   A    D+ +  +    SA +   E  A +   Q+K +       A
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSE--EAPAAMTAAQAKPALKIPQTKA 643

Query: 328 CARKVPADTPQDTKEADSGSRCASRKQG---SQAGPGPQLAQGMRLNAESPTIFIDLRQM 384
           C +K              G++ A RK G   S AG  P +A G +  AE           
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQ-APRKAGTATSPAGSSPAVAGGTQRPAE----------- 691

Query: 385 ELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQK 444
                   +SSS   SDSEEE+      +G A+       GL+    K+  +    +  +
Sbjct: 692 --------DSSSSEESDSEEEKTGLAVTVGQAKSVGK---GLQV---KAASVPVKGSLGQ 737

Query: 445 GTAQPELPASKGP--AGGRAQAPEDTAGSR--------TGRKQHMKLCAKGQSAQARLPR 494
           GTA P LP   GP     +A+  ED+  S               +K   K   A+A    
Sbjct: 738 GTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 796

Query: 495 GR-PRALGDVPEPG 507
            R P A G +  PG
Sbjct: 797 ARAPSAKGTISAPG 810



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 38/121 (31%), Positives = 49/121 (40%), Gaps = 12/121 (9%)

Query: 393 ESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELP 452
           ESSS  SSDSEEE     A L        S +G  +   K        + +KG A P  P
Sbjct: 340 ESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-------ESPRKGAA-PAPP 391

Query: 453 ASKGPAGGRAQA---PEDTAGSRTGRKQHMKLCAKGQ-SAQARLPRGRPRALGDVPEPGA 508
              GPA  +AQA    ED+  S        +  A+ + S +A   R       + P  GA
Sbjct: 392 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451

Query: 509 A 509
           A
Sbjct: 452 A 452



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 17/122 (13%)

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGT----A 447
           PE  S SS +  E EEE  A       AS   L +R  +  +          KGT    A
Sbjct: 266 PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPA----------KGTPGKGA 315

Query: 448 QPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPG 507
            P  P   G    + +A +    S +  ++      +  +A+A L   + +A G   + G
Sbjct: 316 TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL---QAKASGKTSQVG 372

Query: 508 AA 509
           AA
Sbjct: 373 AA 374


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 87/413 (21%), Positives = 141/413 (34%), Gaps = 48/413 (11%)

Query: 66   SEELAEDPADGDKSRAWVAAAEESLPEPVLVP-AELATEPGCRQNTRTKDASSQEGRDPG 124
            SE +    A+GD   A   A  ES  E V  P AE   +P       ++D  + E     
Sbjct: 1848 SEGVEAPEAEGDAQEAEGEAQPES--EDVEAPEAEGEAQP------ESEDVETPEAEWEV 1899

Query: 125  RPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWD----PQAEATLSCHEGD 180
            +P     E       A+     +E      +  T+G   P  +     +AE      EG 
Sbjct: 1900 QPESEGAEAPEAEKEAQPETESVE------ALETEGEDEPESEGAEAQEAEEAAQEAEGQ 1953

Query: 181  PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAE- 239
             + E     SQE+        E  + +E ++  +       P S D     EAP    E 
Sbjct: 1954 TQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV----EAPEAEGEM 2009

Query: 240  -SAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAG--QEDNQGNRAPGTVWWAADH 296
              A     P  +  E  P    +  EA +++   Q   G  Q ++ G  AP     A + 
Sbjct: 2010 QEAEEEAQPESDGVEAQP--KSEGEEAQEVEGETQKTEGDAQPESDGVEAPE----AEEE 2063

Query: 297  RQVQDRMVPSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGS 356
             Q  +  V  A      +   +   +++  A       + P+   EA       + +   
Sbjct: 2064 AQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEG 2123

Query: 357  QAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALG-- 414
            +A P  +  +      E+      +   +      PES    + ++EEE + E+  +   
Sbjct: 2124 EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAP 2183

Query: 415  DAEG-ASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELPASKGPAGGRAQAPE 466
            +AEG A P S G+     +            G AQPEL   + P       PE
Sbjct: 2184 EAEGEAQPESEGIEAPEAE------------GEAQPELEGVEAPEAEEEAQPE 2224



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 89/420 (21%), Positives = 152/420 (36%), Gaps = 62/420 (14%)

Query: 120  GRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWD----PQAEATLS 175
            G+  G      GE +A     ++ P   +G  G  +   +G   P  +    P+AE    
Sbjct: 1805 GQGSGHEDNLQGEAAA---GGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQ 1861

Query: 176  CHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPC 235
              EG+        A  ES +  A   E     E++ ++  T +A      +  G  EAP 
Sbjct: 1862 EAEGE--------AQPESEDVEAPEAEGEAQPESEDVE--TPEAEWEVQPESEGA-EAPE 1910

Query: 236  HAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVWWAAD 295
               E+ P ++       EG      +  EA + ++  Q   GQ   +            +
Sbjct: 1911 AEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESE--------VIE 1962

Query: 296  HRQVQDRMVPSAHNRLMEQLALLCTTQ-SKASACARKVPADTPQDTKEADSGSRCAS-RK 353
             ++ ++   P + +  +E L +   TQ ++  A       + P+   E       A    
Sbjct: 1963 SQEAEEEAQPESED--VEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES 2020

Query: 354  QGSQAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAAL 413
             G +A P  +  +   +  E+     D +         PES    + ++EEE +E    +
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQKTEGDAQ---------PESDGVEAPEAEEEAQEAEGEV 2071

Query: 414  GDAEG-----------------ASPSSLGLRT--CTGKSQLLQQLRAFQ-KGTAQPELPA 453
             +AEG                 A P S G+      G++Q  + + A + +G AQPE   
Sbjct: 2072 QEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG 2131

Query: 454  SKGP-AGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPGAAREA 512
             + P A G AQ PE         +   +  ++G  AQ      +P   G V  P A  EA
Sbjct: 2132 IEAPEAEGEAQ-PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEG-VEAPEAEGEA 2189


>gi|20070205 ladinin 1 [Homo sapiens]
          Length = 517

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 69/320 (21%), Positives = 127/320 (39%), Gaps = 40/320 (12%)

Query: 157 NTKGSQGPPWDPQAEATLSCHEGDPKAE------PLSTASQES-------VNRRALRQER 203
           +T   + P      +   S  E  P  E      PL  AS++        +  R  R++R
Sbjct: 39  STTDDEAPRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQR 98

Query: 204 RKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQL 263
           R+++E        R       +++G    +P  A +    SK  L  PP     LS +Q 
Sbjct: 99  RQVVEAAQAPIQER-----LEAEEGRNSLSPVQATQKPLVSKKELEIPPRRR--LSREQR 151

Query: 264 EAWDLDDILQSLAGQEDNQGNR-----APGTVWWAADHRQVQDRMVPSAHNRLMEQLALL 318
             W L++  +SL G+E  +  +     +P     +   +   ++ + S    + E++   
Sbjct: 152 GPWALEE--ESLVGREPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLA- 208

Query: 319 CTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGPGPQLAQGMRLNAESPTIF 378
               S+ ++ + K+     +++ E  S     S  + S A PG  L  G RL +E  +IF
Sbjct: 209 ----SEKTSLSEKIAVSEKRNSSEKKSVLEKTSVSEKSLA-PGMALGSGRRLVSEKASIF 263

Query: 379 IDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQ 438
               +  L    SP + +  +       E+ +A    A G SP++   +   G++   + 
Sbjct: 264 ----EKALASEKSPTADAKPAPKRATASEQPLAQEPPASGGSPAT--TKEQRGRALPGKN 317

Query: 439 LRAFQK-GTAQPELPASKGP 457
           L +  K G + P   AS+ P
Sbjct: 318 LPSLAKQGASDPPTVASRLP 337


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 35/203 (17%)

Query: 63  PDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEGRD 122
           P++    AE PA         A+AEE++P P    +E             + ASS EG  
Sbjct: 578 PEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSE-------------RSASSVEG-- 622

Query: 123 PGRPFESSGEVSALLGMAEEPPRWLEGDLG--SLSFNTKGSQGPPWDPQAEATLSCHEGD 180
           PG      G + A +   E  P    G++G  SLS + +  + PP DP  +  +S   G 
Sbjct: 623 PG------GALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGK 676

Query: 181 ---------PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVK 231
                    P   P  + +  S ++R      +     +     TRD   PT    G  +
Sbjct: 677 HSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRD---PTPRPPGLPE 733

Query: 232 EAPCHAAESAPRSKMPLVEPPEG 254
           EA   AA S PR++      P G
Sbjct: 734 EATALAAPSPPRARARAAPRPLG 756


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 35/203 (17%)

Query: 63  PDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEGRD 122
           P++    AE PA         A+AEE++P P    +E             + ASS EG  
Sbjct: 573 PEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSE-------------RSASSVEG-- 617

Query: 123 PGRPFESSGEVSALLGMAEEPPRWLEGDLG--SLSFNTKGSQGPPWDPQAEATLSCHEGD 180
           PG      G + A +   E  P    G++G  SLS + +  + PP DP  +  +S   G 
Sbjct: 618 PG------GALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGK 671

Query: 181 ---------PKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVK 231
                    P   P  + +  S ++R      +     +     TRD   PT    G  +
Sbjct: 672 HSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRD---PTPRPPGLPE 728

Query: 232 EAPCHAAESAPRSKMPLVEPPEG 254
           EA   AA S PR++      P G
Sbjct: 729 EATALAAPSPPRARARAAPRPLG 751


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 64/252 (25%), Positives = 95/252 (37%), Gaps = 33/252 (13%)

Query: 39   SDSPLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWV---------AAAEES 89
            +D P+ D   E+  +  R Q     DL+  +    A   KS A +           A   
Sbjct: 963  ADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARR 1022

Query: 90   LPEPVLVPAELATEPG----CRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPR 145
             PE    P   + EPG       + + K+A    G    R    SG V+ LL  A   P 
Sbjct: 1023 PPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPG 1082

Query: 146  WLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTAS-QESVNRRALRQERR 204
                D G    +  G Q P    + EA +   EG P A+  ++A+ +  +  +  +QE  
Sbjct: 1083 E-SADPGPFVEDGTGRQRPRGPSKGEAGV---EGPPLAKVEASATLKRRIRAKQNQQENV 1138

Query: 205  KMI--ETDILQ---KVTRDACGPTS--------SDKGGVKEAPCHAAESAPRSKMPLVEP 251
            K I  E+D ++   K      GP          +  G V+  P  A+E A   ++P   P
Sbjct: 1139 KFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRP--ASEQAGPPELPPPPP 1196

Query: 252  PEGPPVLSLQQL 263
            P  PP   L  L
Sbjct: 1197 PAEPPPTDLAHL 1208


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 72/353 (20%), Positives = 121/353 (34%), Gaps = 35/353 (9%)

Query: 171 EATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETD---ILQKVTRDACGPTSSDK 227
           E T S   G P    LST +   V RR L    R  +E +    L+++  +       D+
Sbjct: 9   EFTRSFFRGRPD---LSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDE 65

Query: 228 GGVKEAPCHAAESAPRSKMPLVEPPE-----------GPPVLSLQQLEAWDLDDILQSLA 276
              +E      +   R   P  +P             G    S         + +   ++
Sbjct: 66  AASREDKLDLTKKGKRPPTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVS 125

Query: 277 GQEDNQGNRAPGTVWWAADHRQVQDRMVPSAHNRLMEQLALLCTTQSKASACARKVPADT 336
             ++    RA   V  ++D  + +D           E+       +       RK P   
Sbjct: 126 PAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEE-------EKGYKGKTRKKPVVK 178

Query: 337 PQDTKEADSGSRCASRKQGSQAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSS 396
            Q   +A S SR  +R++  ++   P      ++     T  +   + E  + +  +   
Sbjct: 179 KQAPGKA-SVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKE 237

Query: 397 HSSSDSEEEEEEEMAALGD------AEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPE 450
               + EEEE+EE    GD      + G   S+   R+C  KSQ  + L        Q E
Sbjct: 238 QREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKE 297

Query: 451 LPASKGPAGGRAQAP--EDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALG 501
             AS G   GR + P  +  +  RT  K   +L    +  +    +G P A G
Sbjct: 298 -AASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDS-GKGEPTAKG 348


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 52/176 (29%), Positives = 65/176 (36%), Gaps = 42/176 (23%)

Query: 104 PGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLG----MAEEPPRWLEGDLGSLSFNTK 159
           P C Q  RT   S   G  PGR    +GE  A LG    + EEPP         L     
Sbjct: 146 PRCTQEGRT---SKDSGEGPGRRRADNGEEGASLGSGWKLTEEPP---------LPPPPP 193

Query: 160 GSQGP-PWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRD 218
             +GP P  P  E       G PK +     ++    R+ ++  R +      L+KV  D
Sbjct: 194 RRKGPLPAGPPPEDV----PGPPKRKEREAGNEPPTPRKKVKGGRERH-----LKKVGGD 244

Query: 219 ACGPTSSDKGGVKEAP------------CHAA---ESAPRSKMPLVEPPEGPPVLS 259
           AC    SD GG    P            CH     E+  + K PL    EGP V S
Sbjct: 245 ACLLRGSDPGGPGLLPPRVLNPSQAFSSCHPGLPPENWEKPKPPLAS-AEGPAVPS 299


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 18/160 (11%)

Query: 333 PADTPQDTKE-ADSGSRCASRKQGSQAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLS 391
           PA  P  ++E A +     S  QG +  PG + AQG    A    +  DL          
Sbjct: 409 PAQAPTSSQELAGAPEPQGSCAQGGRVAPGQRPAQG----ATGTDLDFDL---------- 454

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPEL 451
             S S SSS+SE  +    A+ G++EG            G   L Q         A P L
Sbjct: 455 -SSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSL 513

Query: 452 PASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQAR 491
           P    P         +  G   G +    LC  G     R
Sbjct: 514 PGEAEPGAHAPDKEPELGGQEEGERD--GLCGLGNGCADR 551


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 18/160 (11%)

Query: 333 PADTPQDTKE-ADSGSRCASRKQGSQAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLS 391
           PA  P  ++E A +     S  QG +  PG + AQG    A    +  DL          
Sbjct: 409 PAQAPTSSQELAGAPEPQGSCAQGGRVAPGQRPAQG----ATGTDLDFDL---------- 454

Query: 392 PESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPEL 451
             S S SSS+SE  +    A+ G++EG            G   L Q         A P L
Sbjct: 455 -SSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSL 513

Query: 452 PASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQAR 491
           P    P         +  G   G +    LC  G     R
Sbjct: 514 PGEAEPGAHAPDKEPELGGQEEGERD--GLCGLGNGCADR 551


>gi|239747143 PREDICTED: hypothetical protein XP_002343924 [Homo
           sapiens]
          Length = 319

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 20/124 (16%)

Query: 386 LPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKG 445
           L +  S ES +       EE E E    G   G  P+ LG R C            +++ 
Sbjct: 182 LEEDNSDESDAEGDLGDGEEAEAEAPPAGPRPGPEPAGLGRRPC-----------PYEQA 230

Query: 446 TAQPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPE 505
                  +S+GP G R Q P   A        H+     G+    R+PR   R L  +P 
Sbjct: 231 QGAMGRRSSEGPPGPRTQPPSSPAS-----VYHV----LGRGDPLRVPRCLQRPLSPLPH 281

Query: 506 PGAA 509
            G A
Sbjct: 282 VGDA 285


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 84/417 (20%), Positives = 155/417 (37%), Gaps = 61/417 (14%)

Query: 40   DSPLSDYGEEELFIFQRNQTSLIPDLSEELAE-----DPADGDKSRAWVAAAE------- 87
            D     Y +E    FQ  Q S    LSE++ E     DP   + S   +A +E       
Sbjct: 3118 DMTKRSYADESFHFFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDD 3177

Query: 88   --ESLPEPVL-----VP---AELATEPGCRQNTR--TKDASSQEGRDPGRPFESSGEVSA 135
              + LP+ V      +P   A+L ++ G   +T   TK+A S   +D   P   +G++  
Sbjct: 3178 EADLLPDDVSEEVEEIPASDAQLNSQMGISASTETPTKEAVSVGTKD--LPTVQTGDIPP 3235

Query: 136  LLGM-------AEEPPRWLEGDLGSLS---FNTKGSQGPPWDPQAEATLSCHEGDPKAEP 185
            L G+       + EP   ++ D  +L+   ++ +G   P   P+ + ++      P    
Sbjct: 3236 LSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPTAPMENV 3295

Query: 186  LSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAESAPRSK 245
              T S+  +  R +          +    V+ D       +          A E+ P+SK
Sbjct: 3296 PFTESKSKIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEEN--------KADEAKPKSK 3347

Query: 246  MPLVEPPEGPPVLSLQQLEAWDLDDILQ-SLAGQEDNQGNRAPGTVWWAADHRQVQDRMV 304
            +P+  P      L   + +  DLD  +Q ++A Q  +  + AP       D+R   +   
Sbjct: 3348 LPVKVP------LQRVEQQLSDLDTSVQKTVAPQGQDMASIAP-------DNRSKSESDA 3394

Query: 305  PSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGPGPQL 364
             S  ++    +     T+++  +  R    +  +  + A       SR            
Sbjct: 3395 SSLDSKTKCPVKTRSYTETETESRERAEELEL-ESEEGATRPKILTSRLPVKSRSTTSSC 3453

Query: 365  AQGMRLNAESPTIFIDL--RQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGA 419
              G     ES   F DL    +E  + +S E+S      ++ E E+E+ +  ++  A
Sbjct: 3454 RGGTSPTKESKEHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEIVSDDESSSA 3510


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 44/152 (28%), Positives = 62/152 (40%), Gaps = 30/152 (19%)

Query: 386  LPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLR-TCTGKSQLLQQLRAFQK 444
            +P    P     SSSDSEEEE EE+ ++       P   G R + T      + L   + 
Sbjct: 1908 MPRRPPPSGGLSSSSDSEEEELEELPSV--PRPLQPEFSGSRVSLTDIPTEDEALGTPET 1965

Query: 445  GTAQPELPASKGPAGGRAQ-AP---------EDTAGSRTGRKQHMKLCAKGQSAQARLPR 494
            G A P     +G A  + Q AP         ++ A   + R+  ++   +G SA++ LPR
Sbjct: 1966 GAATPMDWQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPRRGELR---RGSSAESALPR 2022

Query: 495  GRPRALG--------------DVPEPGAAREA 512
              PR LG                P PGA R A
Sbjct: 2023 AGPRELGRGLHKAASVELPQRRSPSPGATRLA 2054


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 289 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 346

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 347 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 403

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 404 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 459

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 460 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 518

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 519 KLS---DSLGQRQP 529


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 308 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 365

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 366 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 422

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 423 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 478

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 479 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 537

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 538 KLS---DSLGQRQP 548


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 302 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 359

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 360 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 416

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 417 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 472

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 473 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 531

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 532 KLS---DSLGQRQP 542


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 343 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 400

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 401 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 457

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 458 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 513

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 514 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 572

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 573 KLS---DSLGQRQP 583


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 404 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 461

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 462 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 518

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 519 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 574

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 575 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 633

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 634 KLS---DSLGQRQP 644


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 407 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 464

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 465 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 521

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 522 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 577

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 578 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 636

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 637 KLS---DSLGQRQP 647


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 385 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 442

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 443 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 499

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 500 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 555

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 556 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 614

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 615 KLS---DSLGQRQP 625


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 391 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 448

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 449 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 505

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 506 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 561

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 562 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 620

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 621 KLS---DSLGQRQP 631


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 321 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 378

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 379 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 435

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 436 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 491

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 492 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 550

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 551 KLS---DSLGQRQP 561


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 54/254 (21%), Positives = 93/254 (36%), Gaps = 14/254 (5%)

Query: 35  PSLDSDS-PLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEP 93
           P+ D D  PL    EE+     R+++ LI +LSE+          S+      E     P
Sbjct: 426 PATDKDGKPLLPEPEEKPK--PRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 483

Query: 94  VLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGS 153
             V   +     C   +   + ++ +G  P    E+  +    LG  E  P   +  +  
Sbjct: 484 APVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---LGKKEADPEDGKPVMDK 540

Query: 154 LSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQ 213
           +    K         + E        D + E +     + +  +  +++   M E  +L 
Sbjct: 541 VKEKAKEEDREKLGEKEETI----PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 596

Query: 214 KVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQ 273
            ++ D  GP ++     ++A   AA S   S+ P      G P     Q +  DLDD L 
Sbjct: 597 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDK-DLDDALD 655

Query: 274 SLAGQEDNQGNRAP 287
            L+   D+ G R P
Sbjct: 656 KLS---DSLGQRQP 666


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,210,490
Number of Sequences: 37866
Number of extensions: 1293490
Number of successful extensions: 7394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 6728
Number of HSP's gapped (non-prelim): 701
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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