Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 5902068
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
(463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 939 0.0
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 639 0.0
gi|11415052 retinoid X receptor, beta [Homo sapiens] 579 e-165
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 279 3e-75
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 278 7e-75
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 272 5e-73
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa... 261 7e-70
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa... 261 7e-70
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa... 261 7e-70
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa... 259 3e-69
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa... 259 3e-69
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa... 259 3e-69
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 257 1e-68
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 223 4e-58
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 222 5e-58
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 221 1e-57
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho... 221 1e-57
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 218 7e-57
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 218 7e-57
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 218 7e-57
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 218 7e-57
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 217 2e-56
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 217 2e-56
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 217 2e-56
gi|238550159 estrogen-related receptor beta [Homo sapiens] 213 4e-55
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo... 210 2e-54
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 196 3e-50
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho... 184 2e-46
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 181 2e-45
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 181 2e-45
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 939 bits (2426), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG 60
MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
Sbjct: 1 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG 60
Query: 61 TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG 120
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
Sbjct: 61 TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG 120
Query: 121 IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD 180
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
Sbjct: 121 IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD 180
Query: 181 CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL 240
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL
Sbjct: 181 CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL 240
Query: 241 EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI 300
EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
Sbjct: 241 EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI 300
Query: 301 LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD 360
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
Sbjct: 301 LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD 360
Query: 361 MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL 420
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
Sbjct: 361 MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL 420
Query: 421 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT 463
LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
Sbjct: 421 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT 463
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 639 bits (1648), Expect = 0.0
Identities = 327/448 (72%), Positives = 367/448 (81%), Gaps = 15/448 (3%)
Query: 20 GHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGP 79
G + S+ PS G P H +P+S TLS+ P+N +G P+ VI+S MGP
Sbjct: 26 GSMAAPSLHPSLGPGIGSPGQLH-----SPIS---TLSS---PINGMGPPFSVISSPMGP 74
Query: 80 PSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMN-YPSTSPGSLVKHI 138
S ++ P + + +N VSSSEDIKP GL G+ + +PS + S KHI
Sbjct: 75 HSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHI 134
Query: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198
CAICGDRSSGKHYGVYSCEGCKGFFKRT+RKDL YTCRDNKDCLIDKRQRNRCQYCRYQK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 199 CLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNM 258
CL MGMKREAVQEERQR ++R E+E E +S +EDMPVERILEAELAVEPKTE+Y + NM
Sbjct: 195 CLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANM 254
Query: 259 ---ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFS 315
+S NDPVTNIC AADKQLFTLVEWAKRIPHFS+L L+DQVILLRAGWNELLIASFS
Sbjct: 255 GLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFS 314
Query: 316 HRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIV 375
HRS++V+DGILLATGLHVHR+SAHSAGVG+IFDRVLTELVSKM+DMQMDK+ELGCLRAIV
Sbjct: 315 HRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIV 374
Query: 376 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435
LFNPD+KGLSNP+EVE LREKVYA+LEAY K KYPEQPGRFAKLLLRLPALRSIGLKCLE
Sbjct: 375 LFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLE 434
Query: 436 HLFFFKLIGDTPIDTFLMEMLETPLQIT 463
HLFFFKLIGDTPIDTFLMEMLE P Q+T
Sbjct: 435 HLFFFKLIGDTPIDTFLMEMLEAPHQMT 462
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 579 bits (1493), Expect = e-165
Identities = 311/464 (67%), Positives = 352/464 (75%), Gaps = 26/464 (5%)
Query: 20 GHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG---------TPLNALGSPY 70
G +G S SP ++ P P P P T ++G P LGSP+
Sbjct: 74 GDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPF 133
Query: 71 RVITSAMGPPSGALAAPPGINLVAPPSS-QLNVVNSVSSS-----EDIKP-LPGLPGIGN 123
VI+S+MG P APPG + P SS Q+N S+ ED+KP + G+ G+ +
Sbjct: 134 PVISSSMGSPGLPPPAPPGFS--GPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGL-H 190
Query: 124 MNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLI 183
P PG+ K +CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDL Y+CRDNKDC +
Sbjct: 191 CPPPPGGPGA-GKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTV 249
Query: 184 DKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAE 243
DKRQRNRCQYCRYQKCL GMKREAVQEERQR +++ + + E A E+MPV+RILEAE
Sbjct: 250 DKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAE 308
Query: 244 LAVEPKTESY-----GDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQ 298
LAVE K++ G +S NDPVTNIC AADKQLFTLVEWAKRIPHFS L L+DQ
Sbjct: 309 LAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQ 368
Query: 299 VILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKM 358
VILLRAGWNELLIASFSHRS+ V+DGILLATGLHVHR+SAHSAGVG+IFDRVLTELVSKM
Sbjct: 369 VILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKM 428
Query: 359 KDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAK 418
+DM+MDK+ELGCLRAI+LFNPDAKGLSNPSEVE LREKVYA+LE Y KQKYPEQ GRFAK
Sbjct: 429 RDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAK 488
Query: 419 LLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQI 462
LLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE P Q+
Sbjct: 489 LLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQL 532
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 279 bits (714), Expect = 3e-75
Identities = 150/354 (42%), Positives = 208/354 (58%), Gaps = 20/354 (5%)
Query: 116 PGLPGI-GNMNYPSTSPGSLVKHI-CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIY 173
P PG G+ G +HI C +CGD+SSGKHYG ++CEGCK FFKR++R++L Y
Sbjct: 61 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY 120
Query: 174 TCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESE---------- 223
TCR N++C ID+ RN+CQYCR +KCL +GM+REAVQ R + +
Sbjct: 121 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLN 180
Query: 224 AECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEW 283
C SG+ + +L AE T YG M+ + + NIC A + LF+ VEW
Sbjct: 181 GHCYLSGY----ISLLLRAE---PYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEW 233
Query: 284 AKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG-ILLATGLHVHRSSAHSAG 342
A+ IP F DL + DQV LLR W+EL + + + S+ + +L A GLH SA
Sbjct: 234 ARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVV 293
Query: 343 VGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLE 402
R+ E V K+K + +D +E CL+AIVLF DA GLS+ + +E+L+EK LE
Sbjct: 294 AFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALE 353
Query: 403 AYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
Y + +YP QP RF KLLLRLP+LR++ +E LFF +L+G TPI+T + +ML
Sbjct: 354 EYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 407
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 278 bits (711), Expect = 7e-75
Identities = 155/386 (40%), Positives = 217/386 (56%), Gaps = 23/386 (5%)
Query: 78 GPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKH 137
GPP GA P P S+ G G P + +H
Sbjct: 31 GPPPGAPHTPQTPGQGGPASTPAQTAAG--------------GQGGPGGPGSDKQQQQQH 76
Query: 138 I-CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRY 196
I C +CGD+SSGKHYG ++CEGCK FFKR++R++L YTCR N++C ID+ RN+CQYCR
Sbjct: 77 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRL 136
Query: 197 QKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAV----EP-KTE 251
+KCL +GM+REAVQ R R + + A + + + L +++ EP T
Sbjct: 137 KKCLKVGMRREAVQ--RGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTS 194
Query: 252 SYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLI 311
+G M+ + + NIC A + LF+ VEWA+ IP F DL + DQV LLR W+EL +
Sbjct: 195 RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFV 254
Query: 312 ASFSHRSVSVQDG-ILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGC 370
+ + S+ + +L A GLH SA R+ E V K+K + +D +E C
Sbjct: 255 LNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSC 314
Query: 371 LRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIG 430
L+AIVLF DA GLS+ + VE+L+EK LE Y + +YP QP RF KLLLRLP+LR++
Sbjct: 315 LKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVS 374
Query: 431 LKCLEHLFFFKLIGDTPIDTFLMEML 456
+E LFF +L+G TPI+T + +ML
Sbjct: 375 SSVIEQLFFVRLVGKTPIETLIRDML 400
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 272 bits (695), Expect = 5e-73
Identities = 148/366 (40%), Positives = 207/366 (56%), Gaps = 19/366 (5%)
Query: 108 SSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTI 167
++ED P PG + P ++ C +CGD+SSGKHYGV++CEGCK FFKR+I
Sbjct: 27 AAEDDSASP--PGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSI 84
Query: 168 RKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER---------QRSRE 218
R++L YTCR N+DC ID+ RN+CQYCR +KC +GM++EAVQ R S
Sbjct: 85 RRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSG 144
Query: 219 RAESEAECATSGHEDM----PVERILEAELAVEPKTESYGDMNMENSTNDPV---TNICH 271
A A + D+ PV ++ L EP + G V N+C
Sbjct: 145 SPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCE 204
Query: 272 AADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG-ILLATG 330
A + LF+ VEWA+ P F +L + DQV LLR W+EL + + + ++ + +L A G
Sbjct: 205 LAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAG 264
Query: 331 LHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEV 390
LH +A A R E V K+ +Q+D +E GCL+AI LF PDA GLS+P+ V
Sbjct: 265 LHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHV 324
Query: 391 ETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 450
E+L+EK L Y + +YP QP RF +LLLRLPALR++ + LFF +L+G TPI+T
Sbjct: 325 ESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIET 384
Query: 451 FLMEML 456
+ +ML
Sbjct: 385 LIRDML 390
>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
sapiens]
Length = 395
Score = 261 bits (668), Expect = 7e-70
Identities = 142/351 (40%), Positives = 210/351 (59%), Gaps = 10/351 (2%)
Query: 106 VSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKR 165
V SS D P G N+N P++ V +CAICGDR++GKHYG SC+GCKGFF+R
Sbjct: 12 VESSYDTSPSEGT----NLNAPNSLG---VSALCAICGDRATGKHYGASSCDGCKGFFRR 64
Query: 166 TIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAE 225
++RK+ +Y+CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S +
Sbjct: 65 SVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYED 124
Query: 226 CATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAK 285
+ + +L ++ P + GD+ + + + ++C + +QL LVEWAK
Sbjct: 125 SSLPSINALLQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAK 181
Query: 286 RIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGS 345
IP F +L L+DQV LLRA E L+ + RS+ +D +LL V R A +
Sbjct: 182 YIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSR 241
Query: 346 IFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT 405
+ R+L ELV +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y
Sbjct: 242 VSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYI 301
Query: 406 KQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
+ + GRF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 302 NDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352
>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
sapiens]
Length = 442
Score = 261 bits (668), Expect = 7e-70
Identities = 142/351 (40%), Positives = 210/351 (59%), Gaps = 10/351 (2%)
Query: 106 VSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKR 165
V SS D P G N+N P++ V +CAICGDR++GKHYG SC+GCKGFF+R
Sbjct: 12 VESSYDTSPSEGT----NLNAPNSLG---VSALCAICGDRATGKHYGASSCDGCKGFFRR 64
Query: 166 TIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAE 225
++RK+ +Y+CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S +
Sbjct: 65 SVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYED 124
Query: 226 CATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAK 285
+ + +L ++ P + GD+ + + + ++C + +QL LVEWAK
Sbjct: 125 SSLPSINALLQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAK 181
Query: 286 RIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGS 345
IP F +L L+DQV LLRA E L+ + RS+ +D +LL V R A +
Sbjct: 182 YIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSR 241
Query: 346 IFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT 405
+ R+L ELV +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y
Sbjct: 242 VSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYI 301
Query: 406 KQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
+ + GRF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 302 NDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352
>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
sapiens]
Length = 452
Score = 261 bits (668), Expect = 7e-70
Identities = 142/351 (40%), Positives = 210/351 (59%), Gaps = 10/351 (2%)
Query: 106 VSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKR 165
V SS D P G N+N P++ V +CAICGDR++GKHYG SC+GCKGFF+R
Sbjct: 12 VESSYDTSPSEGT----NLNAPNSLG---VSALCAICGDRATGKHYGASSCDGCKGFFRR 64
Query: 166 TIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAE 225
++RK+ +Y+CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S +
Sbjct: 65 SVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYED 124
Query: 226 CATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAK 285
+ + +L ++ P + GD+ + + + ++C + +QL LVEWAK
Sbjct: 125 SSLPSINALLQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAK 181
Query: 286 RIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGS 345
IP F +L L+DQV LLRA E L+ + RS+ +D +LL V R A +
Sbjct: 182 YIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSR 241
Query: 346 IFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYT 405
+ R+L ELV +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y
Sbjct: 242 VSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYI 301
Query: 406 KQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
+ + GRF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 302 NDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 352
>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
sapiens]
Length = 417
Score = 259 bits (663), Expect = 3e-69
Identities = 140/342 (40%), Positives = 207/342 (60%), Gaps = 9/342 (2%)
Query: 121 IGNMNYPS-----TSPGSL-VKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYT 174
+GN PS +P SL V +CAICGDR++GKHYG SC+GCKGFF+R++RK+ +Y+
Sbjct: 36 MGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 95
Query: 175 CRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDM 234
CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S + + +
Sbjct: 96 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 155
Query: 235 PVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLT 294
+L ++ P + GD+ + + + ++C + +QL LVEWAK IP F +L
Sbjct: 156 LQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAKYIPAFCELP 212
Query: 295 LEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTEL 354
L+DQV LLRA E L+ + RS+ +D +LL V R A + + R+L EL
Sbjct: 213 LDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDEL 272
Query: 355 VSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPG 414
V +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y + + G
Sbjct: 273 VLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRG 332
Query: 415 RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
RF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 333 RFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374
>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
sapiens]
Length = 464
Score = 259 bits (663), Expect = 3e-69
Identities = 140/342 (40%), Positives = 207/342 (60%), Gaps = 9/342 (2%)
Query: 121 IGNMNYPS-----TSPGSL-VKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYT 174
+GN PS +P SL V +CAICGDR++GKHYG SC+GCKGFF+R++RK+ +Y+
Sbjct: 36 MGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 95
Query: 175 CRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDM 234
CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S + + +
Sbjct: 96 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 155
Query: 235 PVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLT 294
+L ++ P + GD+ + + + ++C + +QL LVEWAK IP F +L
Sbjct: 156 LQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAKYIPAFCELP 212
Query: 295 LEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTEL 354
L+DQV LLRA E L+ + RS+ +D +LL V R A + + R+L EL
Sbjct: 213 LDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDEL 272
Query: 355 VSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPG 414
V +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y + + G
Sbjct: 273 VLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRG 332
Query: 415 RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
RF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 333 RFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374
>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
sapiens]
Length = 474
Score = 259 bits (663), Expect = 3e-69
Identities = 140/342 (40%), Positives = 207/342 (60%), Gaps = 9/342 (2%)
Query: 121 IGNMNYPS-----TSPGSL-VKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYT 174
+GN PS +P SL V +CAICGDR++GKHYG SC+GCKGFF+R++RK+ +Y+
Sbjct: 36 MGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYS 95
Query: 175 CRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDM 234
CR ++ C++DK +RN+C+YCR +KC GMK+EAVQ ER R R S + + +
Sbjct: 96 CRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL 155
Query: 235 PVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLT 294
+L ++ P + GD+ + + + ++C + +QL LVEWAK IP F +L
Sbjct: 156 LQAEVLSRQIT-SPVSGINGDIRAKKIAS--IADVCESMKEQLLVLVEWAKYIPAFCELP 212
Query: 295 LEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTEL 354
L+DQV LLRA E L+ + RS+ +D +LL V R A + + R+L EL
Sbjct: 213 LDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDEL 272
Query: 355 VSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPG 414
V +++Q+D +E L+AI+ F+PDAKGLS+P +++ LR +V +LE Y + + G
Sbjct: 273 VLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRG 332
Query: 415 RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
RF +LLL LP L+SI + +E + F KL G ID L EML
Sbjct: 333 RFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEML 374
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 257 bits (657), Expect = 1e-68
Identities = 135/322 (41%), Positives = 199/322 (61%), Gaps = 4/322 (1%)
Query: 135 VKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYC 194
V +CAICGDR++GKHYG SC+GCKGFF+R+IRK +Y+CR ++ C++DK +RN+C+YC
Sbjct: 45 VNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYC 104
Query: 195 RYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYG 254
R +KC GMK+EAVQ ER R R + + + +++V S
Sbjct: 105 RLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSS-T 163
Query: 255 DMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASF 314
D+N++ + + ++C + +QL LVEWAK IP F +L L+DQV LLRA E L+
Sbjct: 164 DINVKKIAS--IGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGA 221
Query: 315 SHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAI 374
+ RS+ +D +LL +HR+S + + +RVL ELV +++Q+D +E CL+AI
Sbjct: 222 TKRSMMYKDILLLGNNYVIHRNSC-EVEISRVANRVLDELVRPFQEIQIDDNEYACLKAI 280
Query: 375 VLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCL 434
V F+PDAKGLS+P +++ +R +V LE Y + + GRF +LLL LP L+SI + +
Sbjct: 281 VFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMI 340
Query: 435 EHLFFFKLIGDTPIDTFLMEML 456
E + F KL G ID L EML
Sbjct: 341 EQIQFVKLFGMVKIDNLLQEML 362
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 223 bits (567), Expect = 4e-58
Identities = 134/409 (32%), Positives = 210/409 (51%), Gaps = 33/409 (8%)
Query: 71 RVITSAMGPPSGALAAPPGINLVA--------PPSSQLNVVNSVSSSEDIKPLPGLPGIG 122
R + A GP +G L G + A P+S +V +SSE++ P
Sbjct: 13 RRLYGAAGPGAGLLRRATGGSCFAGLESFAWPQPASLQSVETQSTSSEEMVP-------- 64
Query: 123 NMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCL 182
+ PS P V C +C D+SSG HYGV SCEGCKGFF+R+I+K+++YTC +K+C+
Sbjct: 65 --SSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCI 122
Query: 183 IDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMP-----VE 237
I+K RNRCQYCR QKC +GM +EAV+ +R + ++ + E + +E P +
Sbjct: 123 INKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEG--SPDSYELSPQLEELIT 180
Query: 238 RILEAELAVEPKTESYGDMNMENSTNDPV-------TNICHAADKQLFTLVEWAKRIPHF 290
++ +A P G +S + V A K + +VE+AKR+P F
Sbjct: 181 KVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGF 240
Query: 291 SDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRV 350
+ L++ DQ+ LL+A ++L+ R QD + + GL ++R+ H+AG G + D V
Sbjct: 241 TGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV 300
Query: 351 LTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYP 410
++ ++MD +E G L AI L D L P +V+ L+E + L Y +++ P
Sbjct: 301 FA-FAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRP 359
Query: 411 EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETP 459
QP F ++L+++ LR I K E K+ P+ + EMLE P
Sbjct: 360 SQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENP 408
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 222 bits (566), Expect = 5e-58
Identities = 129/362 (35%), Positives = 200/362 (55%), Gaps = 23/362 (6%)
Query: 107 SSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRT 166
+SSE++ P P PS P V C +C D+SSG HYGV +CEGCKGFF+R+
Sbjct: 59 TSSEELVPSP----------PSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRS 108
Query: 167 IRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAEC 226
I+K++IYTC +K+C+I+K RNRCQYCR QKC +GM +E+V+ +R + +++ S+ EC
Sbjct: 109 IQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK-KKKETSKQEC 167
Query: 227 ATS----GHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPV-------TNICHAADK 275
S D E+I +A P G +S + V A K
Sbjct: 168 TESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATK 227
Query: 276 QLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHR 335
+ +VE+AKR+P F+ LT+ DQ+ LL+A ++LI R QD + + GL ++R
Sbjct: 228 CIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNR 287
Query: 336 SSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLRE 395
+ H+AG G + D V T +++ ++MD +E G L AI L D + L P++V+ L+E
Sbjct: 288 TQMHNAGFGPLTDLVFT-FANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQE 346
Query: 396 KVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEM 455
+ L+ Y +++ P +P F K+L+++ LRSI K E + K+ + + EM
Sbjct: 347 PLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEM 406
Query: 456 LE 457
LE
Sbjct: 407 LE 408
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 221 bits (563), Expect = 1e-57
Identities = 133/416 (31%), Positives = 211/416 (50%), Gaps = 29/416 (6%)
Query: 60 GTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPP----SSQLNVVNSVSSSEDIKPL 115
G+ G P+ + G P + +P L P + L+V +SSE++ P
Sbjct: 17 GSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVP- 75
Query: 116 PGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTC 175
+ PS P V C +C D+SSG HYGV SCEGCKGFF+R+I+K+++YTC
Sbjct: 76 ---------SSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTC 126
Query: 176 RDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMP 235
+K+C+I+K RNRCQYCR QKC +GM +EAV+ +R + ++ + E + +E P
Sbjct: 127 HRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEG--SPDSYELSP 184
Query: 236 -----VERILEAELAVEPKTESYGDMNMENSTNDPV-------TNICHAADKQLFTLVEW 283
+ ++ +A P G +S + V A K + +VE+
Sbjct: 185 QLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEF 244
Query: 284 AKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGV 343
AKR+P F+ L++ DQ+ LL+A ++L+ R QD + + GL ++R+ H+AG
Sbjct: 245 AKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGF 304
Query: 344 GSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEA 403
G + D V ++ ++MD +E G L AI L D L P +V+ L+E + L
Sbjct: 305 GPLTDLVFA-FAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRL 363
Query: 404 YTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETP 459
Y +++ P QP F ++L+++ LR I K E K+ P+ + EMLE P
Sbjct: 364 YARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENP 419
>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
sapiens]
Length = 410
Score = 221 bits (562), Expect = 1e-57
Identities = 142/413 (34%), Positives = 209/413 (50%), Gaps = 65/413 (15%)
Query: 97 SSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSC 156
SS + + + K PG G+G P+ SL C +CGD SSGKHYG+Y+C
Sbjct: 10 SSTVAAAAPAAGAASRKESPGRWGLGED--PTGVSPSLQ---CRVCGDSSSGKHYGIYAC 64
Query: 157 EGCKGFFKRTIRKDLIYTCRDNKD-CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQR 215
GC GFFKR++R+ LIY C+ C +DK RN+CQ CR +KCL GM ++AVQ ERQ
Sbjct: 65 NGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQ- 123
Query: 216 SRERAESEAECATSGHEDMP------------------------------VERILEAELA 245
R A+ + S E P + ++ AE
Sbjct: 124 PRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETC 183
Query: 246 VEPKTESYGDMNMENSTNDP--------------VTNICHAADKQLFTLVEWAKRIPHFS 291
+ + E D N++ ++NDP + +I + + LF V+WAK +P FS
Sbjct: 184 AKLEPED-ADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFS 242
Query: 292 DLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAG-------VG 344
L DQVILL W+EL + S+ + LLA A +AG +
Sbjct: 243 SLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAP------PEASAAGGAQGRLTLA 296
Query: 345 SIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAY 404
S+ RVL E +S+ + + +D +E C++A+VLF P+ +GL +P VE L+++ L +
Sbjct: 297 SMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQH 356
Query: 405 TKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
+K +P QP RF KLLL LP+LR I + +E LFF K IG+TP++ L +M +
Sbjct: 357 SKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFK 409
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 218 bits (556), Expect = 7e-57
Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 99 SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 158
Query: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243
CR+ KCL +GM +E V+ +R R R++ + + S + P +I+
Sbjct: 159 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 218
Query: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
L EP K + D + +S +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 219 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 278
Query: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
++ W E+LI +RS+S +D ++ A + + AG+ + + +L +LV K K M+
Sbjct: 279 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 337
Query: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
++K E L+AI L N D+ + + V+ L++ ++ L+ Y ++ E P R K+L+
Sbjct: 338 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 397
Query: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
LP LR K ++H + KL G P+ +EMLE
Sbjct: 398 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 218 bits (556), Expect = 7e-57
Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 99 SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 158
Query: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243
CR+ KCL +GM +E V+ +R R R++ + + S + P +I+
Sbjct: 159 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 218
Query: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
L EP K + D + +S +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 219 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 278
Query: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
++ W E+LI +RS+S +D ++ A + + AG+ + + +L +LV K K M+
Sbjct: 279 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 337
Query: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
++K E L+AI L N D+ + + V+ L++ ++ L+ Y ++ E P R K+L+
Sbjct: 338 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 397
Query: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
LP LR K ++H + KL G P+ +EMLE
Sbjct: 398 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 218 bits (556), Expect = 7e-57
Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 122 SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 181
Query: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243
CR+ KCL +GM +E V+ +R R R++ + + S + P +I+
Sbjct: 182 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 241
Query: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
L EP K + D + +S +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 242 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 301
Query: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
++ W E+LI +RS+S +D ++ A + + AG+ + + +L +LV K K M+
Sbjct: 302 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 360
Query: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
++K E L+AI L N D+ + + V+ L++ ++ L+ Y ++ E P R K+L+
Sbjct: 361 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 420
Query: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
LP LR K ++H + KL G P+ +EMLE
Sbjct: 421 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 455
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 218 bits (556), Expect = 7e-57
Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 99 SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 158
Query: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243
CR+ KCL +GM +E V+ +R R R++ + + S + P +I+
Sbjct: 159 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 218
Query: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
L EP K + D + +S +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 219 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 278
Query: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
++ W E+LI +RS+S +D ++ A + + AG+ + + +L +LV K K M+
Sbjct: 279 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 337
Query: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
++K E L+AI L N D+ + + V+ L++ ++ L+ Y ++ E P R K+L+
Sbjct: 338 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 397
Query: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
LP LR K ++H + KL G P+ +EMLE
Sbjct: 398 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 217 bits (553), Expect = 2e-56
Identities = 125/371 (33%), Positives = 198/371 (53%), Gaps = 23/371 (6%)
Query: 98 SQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCE 157
S + SSSE+I P P PS P + C +C D+SSG HYGV +CE
Sbjct: 57 SPATIETQSSSSEEIVPSP----------PSPPPLPRIYKPCFVCQDKSSGYHYGVSACE 106
Query: 158 GCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSR 217
GCKGFF+R+I+K+++YTC +K+C+I+K RNRCQYCR QKC +GM +E+V+ +R + +
Sbjct: 107 GCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKK 166
Query: 218 ERAESEAECATS----GHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVT------ 267
+ + EC+ S +E++ +A P G NS+ V+
Sbjct: 167 KEV-PKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLW 225
Query: 268 -NICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGIL 326
+ K + VE+AK++P F+ LT+ DQ+ LL+A ++LI R QD +
Sbjct: 226 DKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMT 285
Query: 327 LATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSN 386
+ GL ++R+ H+AG G + D V +++ ++MD +E G L AI L D + L
Sbjct: 286 FSDGLTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQ 344
Query: 387 PSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT 446
P V+ L+E + L+ Y +++ P +P F K+L+++ LRSI K E + K+
Sbjct: 345 PDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG 404
Query: 447 PIDTFLMEMLE 457
+ + EMLE
Sbjct: 405 SMPPLIQEMLE 415
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 217 bits (553), Expect = 2e-56
Identities = 125/371 (33%), Positives = 199/371 (53%), Gaps = 23/371 (6%)
Query: 98 SQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCE 157
S ++ SSSE+I P P PS P + C +C D+SSG HYGV +CE
Sbjct: 52 SNHSIETQSSSSEEIVPSP----------PSPPPLPRIYKPCFVCQDKSSGYHYGVSACE 101
Query: 158 GCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSR 217
GCKGFF+R+I+K+++YTC +K+C+I+K RNRCQYCR QKC +GM +E+V+ +R + +
Sbjct: 102 GCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKK 161
Query: 218 ERAESEAECATS----GHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVT------ 267
+ + EC+ S +E++ +A P G NS+ V+
Sbjct: 162 KEV-PKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLW 220
Query: 268 -NICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGIL 326
+ K + VE+AK++P F+ LT+ DQ+ LL+A ++LI R QD +
Sbjct: 221 DKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMT 280
Query: 327 LATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSN 386
+ GL ++R+ H+AG G + D V +++ ++MD +E G L AI L D + L
Sbjct: 281 FSDGLTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQ 339
Query: 387 PSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT 446
P V+ L+E + L+ Y +++ P +P F K+L+++ LRSI K E + K+
Sbjct: 340 PDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG 399
Query: 447 PIDTFLMEMLE 457
+ + EMLE
Sbjct: 400 SMPPLIQEMLE 410
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 217 bits (553), Expect = 2e-56
Identities = 125/371 (33%), Positives = 198/371 (53%), Gaps = 23/371 (6%)
Query: 98 SQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCE 157
S + SSSE+I P P PS P + C +C D+SSG HYGV +CE
Sbjct: 57 SPATIETQSSSSEEIVPSP----------PSPPPLPRIYKPCFVCQDKSSGYHYGVSACE 106
Query: 158 GCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSR 217
GCKGFF+R+I+K+++YTC +K+C+I+K RNRCQYCR QKC +GM +E+V+ +R + +
Sbjct: 107 GCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKK 166
Query: 218 ERAESEAECATS----GHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVT------ 267
+ + EC+ S +E++ +A P G NS+ V+
Sbjct: 167 KEV-PKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLW 225
Query: 268 -NICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGIL 326
+ K + VE+AK++P F+ LT+ DQ+ LL+A ++LI R QD +
Sbjct: 226 DKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMT 285
Query: 327 LATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSN 386
+ GL ++R+ H+AG G + D V +++ ++MD +E G L AI L D + L
Sbjct: 286 FSDGLTLNRTQMHNAGFGPLTDLVFA-FANQLLPLEMDDAETGLLSAICLICGDRQDLEQ 344
Query: 387 PSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT 446
P V+ L+E + L+ Y +++ P +P F K+L+++ LRSI K E + K+
Sbjct: 345 PDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG 404
Query: 447 PIDTFLMEMLE 457
+ + EMLE
Sbjct: 405 SMPPLIQEMLE 415
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 213 bits (541), Expect = 4e-55
Identities = 117/335 (34%), Positives = 186/335 (55%), Gaps = 11/335 (3%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
++ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 97 AIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 156
Query: 193 YCRYQKCLVMGMKREAVQEE-----RQRSRERAESEA----ECATSGHEDMPVERILEAE 243
CR+ KCL +GM +E V+ + RQ+ + R +SE+ S P+ +I+
Sbjct: 157 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYL 216
Query: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
L EP K + M +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 217 LVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLL 276
Query: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
++ W E+LI +RS+ D ++ A + + AG+ ++ R + +LV + K ++
Sbjct: 277 QSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELY-RAILQLVRRYKKLK 335
Query: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
++K E L+A+ L N D+ + + V+ L++ ++ L+ Y + E+P R KLLL
Sbjct: 336 VEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLT 395
Query: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
LP LR K ++H + KL G P+ +EMLE
Sbjct: 396 LPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLE 430
>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
sapiens]
Length = 385
Score = 210 bits (534), Expect = 2e-54
Identities = 120/383 (31%), Positives = 190/383 (49%), Gaps = 49/383 (12%)
Query: 124 MNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD--C 181
M+ P+ S ++ C +CGDRSSGKHYGVY+C+GC GFFKR+IR++ Y C+ C
Sbjct: 1 MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGC 60
Query: 182 LIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHED-------- 233
+DK RN+C+ CR +KCL + M ++AVQ ER + GH++
Sbjct: 61 PVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHF 120
Query: 234 ----MPVERILEAELAVEPKTESYGDMNMENSTNDPVT---------------------- 267
+P A +EP ++ V+
Sbjct: 121 PSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEV 180
Query: 268 ---NICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG 324
++C +A + LF ++WAK +P FS L+L+DQ++LL W EL + + ++ V
Sbjct: 181 ATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDAN 240
Query: 325 ILLATGLHVHRSSAHSAGVGSIFDRV--LTELVSKMKDMQMDKSELGCLRAIVLFNP--- 379
LLA ++ + S + I + L E+V++ + +++D +E CL+ IV F
Sbjct: 241 TLLAVS-GMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPT 299
Query: 380 ----DAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435
+ + N + + L+++ TL +Y +YP QP RF KLLL LPALRSI +E
Sbjct: 300 HSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIE 359
Query: 436 HLFFFKLIGDTPIDTFLMEMLET 458
+FF K IG+ PI L +M ++
Sbjct: 360 EVFFKKTIGNVPITRLLSDMYKS 382
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 196 bits (499), Expect = 3e-50
Identities = 120/348 (34%), Positives = 183/348 (52%), Gaps = 24/348 (6%)
Query: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
SL K +C +CGD +SG HYGV SCE CK FFKRTI+ + Y+C + +C I KR+R CQ
Sbjct: 73 SLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQ 132
Query: 193 YCRYQKCLVMGMKREAVQEE-----RQRSRERAESE----------AECATSG---HEDM 234
CR+ KCL +GM +E V+ + RQ+ + R E + A +G
Sbjct: 133 ACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAA 192
Query: 235 PVERILEAELAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDL 293
PV ++ L VEP K + D + V +C D+++ + WAK IP FS L
Sbjct: 193 PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSL 252
Query: 294 TLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTE 353
+L DQ+ +L++ W E+L+ + RS+ +QD + A L + A +AG+G + L +
Sbjct: 253 SLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGEL-GAALLQ 311
Query: 354 LVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQP 413
LV +++ +++++ E L+A+ L N D+ + + VE LRE ++ L Y +
Sbjct: 312 LVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGG 371
Query: 414 G----RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
G R +LLL LP LR K L H + KL G P+ +EMLE
Sbjct: 372 GAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLE 419
>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
sapiens]
Length = 367
Score = 184 bits (466), Expect = 2e-46
Identities = 121/371 (32%), Positives = 180/371 (48%), Gaps = 65/371 (17%)
Query: 97 SSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSC 156
SS + + + K PG G+G P+ SL C +CGD SSGKHYG+Y+C
Sbjct: 10 SSTVAAAAPAAGAASRKESPGRWGLGED--PTGVSPSLQ---CRVCGDSSSGKHYGIYAC 64
Query: 157 EGCKGFFKRTIRKDLIYTCRDNKD-CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQR 215
GC GFFKR++R+ LIY C+ C +DK RN+CQ CR +KCL GM ++AVQ ERQ
Sbjct: 65 NGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQ- 123
Query: 216 SRERAESEAECATSGHEDMP------------------------------VERILEAELA 245
R A+ + S E P + ++ AE
Sbjct: 124 PRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETC 183
Query: 246 VEPKTESYGDMNMENSTNDP--------------VTNICHAADKQLFTLVEWAKRIPHFS 291
+ + E D N++ ++NDP + +I + + LF V+WAK +P FS
Sbjct: 184 AKLEPED-ADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFS 242
Query: 292 DLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAG-------VG 344
L DQVILL W+EL + S+ + LLA A +AG +
Sbjct: 243 SLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAP------PEASAAGGAQGRLTLA 296
Query: 345 SIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAY 404
S+ RVL E +S+ + + +D +E C++A+VLF P+ +GL +P VE L+++ L +
Sbjct: 297 SMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQH 356
Query: 405 TKQKYPEQPGR 415
+K +P QP R
Sbjct: 357 SKAHHPSQPVR 367
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 181 bits (458), Expect = 2e-45
Identities = 131/421 (31%), Positives = 207/421 (49%), Gaps = 33/421 (7%)
Query: 65 ALGSPYRVITSAMGPPSG---ALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPL----PG 117
A G P + PP+G +LA P + + QL S S L P
Sbjct: 180 ASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPH 239
Query: 118 LPGIGNMNYPSTS-------PGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKD 170
L G G ++ P TS PG CA+CGD +S +HYGV +CEGCKGFFKRT++K+
Sbjct: 240 LEGSGILDTPVTSTKARSGAPGGSEGR-CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKN 298
Query: 171 LIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRE-RAESEAECATS 229
Y C NKDC +DKR+RNRCQ+CR+QKCL +GM +E V+ + + R R S+ +
Sbjct: 299 AKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPD 358
Query: 230 GHEDMPVERILEAELAVEPKT-----ESYGDMNMENSTNDPVTNICHAAD---KQLFTLV 281
+ ++ A L P T + ++ + + + ++ D L +
Sbjct: 359 ASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIR 418
Query: 282 EWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA 341
+WA++IP F++L+ DQ +LL + + EL I ++RS + ++ +GL +HR +
Sbjct: 419 KWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-AR 477
Query: 342 GVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATL 401
G G D +L + + +D CL A+VL D GL P VE L+ ++ + L
Sbjct: 478 GFGDWIDSILA-FSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCL 535
Query: 402 EAYTK--QKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEM 455
+ + P+ ++LL +LP LR++ + L+ +F+ KL P ID M+
Sbjct: 536 KEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDT 595
Query: 456 L 456
L
Sbjct: 596 L 596
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 181 bits (458), Expect = 2e-45
Identities = 131/421 (31%), Positives = 207/421 (49%), Gaps = 33/421 (7%)
Query: 65 ALGSPYRVITSAMGPPSG---ALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPL----PG 117
A G P + PP+G +LA P + + QL S S L P
Sbjct: 180 ASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPH 239
Query: 118 LPGIGNMNYPSTS-------PGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKD 170
L G G ++ P TS PG CA+CGD +S +HYGV +CEGCKGFFKRT++K+
Sbjct: 240 LEGSGILDTPVTSTKARSGAPGGSEGR-CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKN 298
Query: 171 LIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRE-RAESEAECATS 229
Y C NKDC +DKR+RNRCQ+CR+QKCL +GM +E V+ + + R R S+ +
Sbjct: 299 AKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPD 358
Query: 230 GHEDMPVERILEAELAVEPKT-----ESYGDMNMENSTNDPVTNICHAAD---KQLFTLV 281
+ ++ A L P T + ++ + + + ++ D L +
Sbjct: 359 ASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIR 418
Query: 282 EWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA 341
+WA++IP F++L+ DQ +LL + + EL I ++RS + ++ +GL +HR +
Sbjct: 419 KWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQC-AR 477
Query: 342 GVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATL 401
G G D +L + + +D CL A+VL D GL P VE L+ ++ + L
Sbjct: 478 GFGDWIDSILA-FSRSLHSLLVDVPAFACLSALVLIT-DRHGLQEPRRVEELQNRIASCL 535
Query: 402 EAYTK--QKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP----IDTFLMEM 455
+ + P+ ++LL +LP LR++ + L+ +F+ KL P ID M+
Sbjct: 536 KEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDT 595
Query: 456 L 456
L
Sbjct: 596 L 596
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,162,083
Number of Sequences: 37866
Number of extensions: 966675
Number of successful extensions: 5205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 4525
Number of HSP's gapped (non-prelim): 650
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.