Search of human proteins with 56711320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
         (774 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56711320 hypothetical protein LOC145407 [Homo sapiens]            1516   0.0  
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    63   1e-09
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            63   1e-09
gi|91982772 mucin 17 [Homo sapiens]                                    59   1e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        55   3e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    55   3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    54   6e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        54   6e-07
gi|55956788 nucleolin [Homo sapiens]                                   53   1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens]               52   2e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    52   2e-06
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    52   2e-06
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    52   2e-06
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    52   2e-06
gi|115529449 upstream binding transcription factor, RNA polymera...    52   2e-06
gi|115529451 upstream binding transcription factor, RNA polymera...    52   2e-06
gi|7657671 upstream binding transcription factor, RNA polymerase...    52   2e-06
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    52   3e-06
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    51   4e-06
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    51   5e-06
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              51   5e-06
gi|4504425 high-mobility group box 1 [Homo sapiens]                    50   6e-06

>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
          Length = 774

 Score = 1516 bits (3924), Expect = 0.0
 Identities = 774/774 (100%), Positives = 774/774 (100%)

Query: 1   MRGPIVLHICLAFCSLLLFSVATQCLAFPKIERRREIAHVHAEKGQSDKMNTDDLENSSV 60
           MRGPIVLHICLAFCSLLLFSVATQCLAFPKIERRREIAHVHAEKGQSDKMNTDDLENSSV
Sbjct: 1   MRGPIVLHICLAFCSLLLFSVATQCLAFPKIERRREIAHVHAEKGQSDKMNTDDLENSSV 60

Query: 61  TSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESGVP 120
           TSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESGVP
Sbjct: 61  TSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESGVP 120

Query: 121 SAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETT 180
           SAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETT
Sbjct: 121 SAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETT 180

Query: 181 KGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAE 240
           KGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAE
Sbjct: 181 KGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAE 240

Query: 241 STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSV 300
           STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSV
Sbjct: 241 STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSV 300

Query: 301 STAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWT 360
           STAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWT
Sbjct: 301 STAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWT 360

Query: 361 EAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGD 420
           EAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGD
Sbjct: 361 EAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGD 420

Query: 421 FTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQE 480
           FTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQE
Sbjct: 421 FTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQE 480

Query: 481 QVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVE 540
           QVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVE
Sbjct: 481 QVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVE 540

Query: 541 EQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAA 600
           EQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAA
Sbjct: 541 EQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAA 600

Query: 601 SYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPG 660
           SYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPG
Sbjct: 601 SYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPG 660

Query: 661 ITSQEPGLEEGNMDLLEGATYQVPDALEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGV 720
           ITSQEPGLEEGNMDLLEGATYQVPDALEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGV
Sbjct: 661 ITSQEPGLEEGNMDLLEGATYQVPDALEWEQQNQGLVRSWMEKLKDKAGYMSGMLVPVGV 720

Query: 721 GIAGALFILGALYSIKVMNRRRRNGFKRHKRKQREFNSMQDRVMLLADSSEDEF 774
           GIAGALFILGALYSIKVMNRRRRNGFKRHKRKQREFNSMQDRVMLLADSSEDEF
Sbjct: 721 GIAGALFILGALYSIKVMNRRRRNGFKRHKRKQREFNSMQDRVMLLADSSEDEF 774


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 121/556 (21%), Positives = 186/556 (33%), Gaps = 48/556 (8%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSET- 1203

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTE----EEKEDPSPV 504
                 T     ++  T +    +   +  T  + +T         T      E    S  
Sbjct: 1204 ----TTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1259

Query: 505  SDVPGVTQLSRRWEPL-------ATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVL 557
            S  P  T L+             AT  STTV   +F +T   +  +  +T      T   
Sbjct: 1260 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1319

Query: 558  GSPVTPPGIMVGEPSI 573
            G+ +T    +   P +
Sbjct: 1320 GTRLTASSSVTMAPGM 1335



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 57/264 (21%), Positives = 95/264 (35%), Gaps = 12/264 (4%)

Query: 104  MQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAI-TATPSLTVDEKEE 162
            + T   G +T + +G  +       S+    S E   A  + T +  T T S T  E   
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 163  LLTSTNFQPIVEEI-TETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPK 221
            + T+ +    V  I +E T       +  + +TE  E        ++  +T    TT   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE--------TTTASTAGSETTTAS 1197

Query: 222  TEKFEADTDHRTTSFPGAESTAGSEPGSL--TPDKEKPSQMTADNTQAAATKQPLETSEY 279
            T   E  T     S     ST+GSE  +   T  +          T  A       T   
Sbjct: 1198 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1257

Query: 280  TLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVR 339
            T S+EP   SL G+   TVS++ +   A++ +       L   + +    + +   +  R
Sbjct: 1258 TASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTR 1317

Query: 340  TEMSQTAQVSHEGMEGGQPWTEAA 363
            T  ++    S   M  G  +T +A
Sbjct: 1318 TTGTRLTASSSVTMAPGMDFTASA 1341


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 121/547 (22%), Positives = 182/547 (33%), Gaps = 40/547 (7%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKT--EEEKEDPSPVSD 506
                 T       E  TA      T +  +         I  S  T       +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
                T         AT  STTV   +F +T   +  +  +T      T   G+ +T    
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1318

Query: 567  MVGEPSI 573
            +   P +
Sbjct: 1319 VTMAPGM 1325



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 121/547 (22%), Positives = 183/547 (33%), Gaps = 40/547 (7%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTA--VQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSD 506
                 T       E  TA       +T S    E      +  +S        +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
                T         AT  STTV   +F +T   +  +  +T      T   G+ +T    
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1318

Query: 567  MVGEPSI 573
            +   P +
Sbjct: 1319 VTMAPGM 1325



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 207 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 263

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 264 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 322

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 323 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 382

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 383 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 442

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 443 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 493

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 494 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 549

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 550 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 603

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 604 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 663

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 664 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 707



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 543  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 601

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 602  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 661

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 662  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 721

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 722  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 779

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 780  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 839

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 840  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 899

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 900  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 959

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 960  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 1013

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 1014 TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1053

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1054 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1114 TTTASTAG 1121



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 121/547 (22%), Positives = 182/547 (33%), Gaps = 40/547 (7%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 820  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 879

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 880  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 938

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 939  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 998

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 999  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1058

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1059 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1118

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1119 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1165

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1166 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1223

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKT--EEEKEDPSPVSD 506
                 T       E  TA      T +  +         I  S  T       +P+  S 
Sbjct: 1224 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1279

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
                T         AT  STTV   +F +T   +  +  +T      T   G+ +T    
Sbjct: 1280 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1339

Query: 567  MVGEPSI 573
            +   P +
Sbjct: 1340 VTMAPGM 1346



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 44  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 103

Query: 229 TDHRTTSFPGAEST---AGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+EST   AGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 104 SGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 163

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 164 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 223

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 224 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 270

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 271 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 322

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 323 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 378

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 379 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 434

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 435 TTT-----CTEGSEMTAVSTTVFETTTASTEG 461



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 63  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAG 122

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 123 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 182

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 183 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 242

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 243 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 301

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 302 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 355

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 356 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 414

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 415 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 469

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 470 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 527

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 528 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 583



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 1020 EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1079

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1080 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1139

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1140 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1199

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1200 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1258

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1259 IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1318

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1319 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1352


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 121/547 (22%), Positives = 182/547 (33%), Gaps = 40/547 (7%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKT--EEEKEDPSPVSD 506
                 T       E  TA      T +  +         I  S  T       +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
                T         AT  STTV   +F +T   +  +  +T      T   G+ +T    
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1318

Query: 567  MVGEPSI 573
            +   P +
Sbjct: 1319 VTMAPGM 1325



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 121/536 (22%), Positives = 180/536 (33%), Gaps = 45/536 (8%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKT--EEEKEDPSPVSD 506
                 T       E  TA      T +  +         I  S  T       +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVT 562
                T         AT  STTV   +F +T   +  +  +T      TP+ G+  T
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN-----TPMSGTRTT 1309



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 121/536 (22%), Positives = 180/536 (33%), Gaps = 45/536 (8%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKT--EEEKEDPSPVSD 506
                 T       E  TA      T +  +         I  S  T       +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVT 562
                T         AT  STTV   +F +T   +  +  +T      TP+ G+  T
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN-----TPMSGTRTT 1309



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 121/556 (21%), Positives = 186/556 (33%), Gaps = 48/556 (8%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSET- 1203

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTE----EEKEDPSPV 504
                 T     ++  T +    +   +  T  + +T         T      E    S  
Sbjct: 1204 ----TTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1259

Query: 505  SDVPGVTQLSRRWEPL-------ATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVL 557
            S  P  T L+             AT  STTV   +F +T   +  +  +T      T   
Sbjct: 1260 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1319

Query: 558  GSPVTPPGIMVGEPSI 573
            G+ +T    +   P +
Sbjct: 1320 GTRLTASSSVTMAPGM 1335



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 57/264 (21%), Positives = 95/264 (35%), Gaps = 12/264 (4%)

Query: 104  MQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAI-TATPSLTVDEKEE 162
            + T   G +T + +G  +       S+    S E   A  + T +  T T S T  E   
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 163  LLTSTNFQPIVEEI-TETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPK 221
            + T+ +    V  I +E T       +  + +TE  E        ++  +T    TT   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE--------TTTASTAGSETTTAS 1197

Query: 222  TEKFEADTDHRTTSFPGAESTAGSEPGSL--TPDKEKPSQMTADNTQAAATKQPLETSEY 279
            T   E  T     S     ST+GSE  +   T  +          T  A       T   
Sbjct: 1198 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1257

Query: 280  TLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVR 339
            T S+EP   SL G+   TVS++ +   A++ +       L   + +    + +   +  R
Sbjct: 1258 TASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTR 1317

Query: 340  TEMSQTAQVSHEGMEGGQPWTEAA 363
            T  ++    S   M  G  +T +A
Sbjct: 1318 TTGTRLTASSSVTMAPGMDFTASA 1341


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 121/556 (21%), Positives = 186/556 (33%), Gaps = 48/556 (8%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSET- 1203

Query: 449  QLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTE----EEKEDPSPV 504
                 T     ++  T +    +   +  T  + +T         T      E    S  
Sbjct: 1204 ----TTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1259

Query: 505  SDVPGVTQLSRRWEPL-------ATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVL 557
            S  P  T L+             AT  STTV   +F +T   +  +  +T      T   
Sbjct: 1260 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1319

Query: 558  GSPVTPPGIMVGEPSI 573
            G+ +T    +   P +
Sbjct: 1320 GTRLTASSSVTMAPGM 1335



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 57/264 (21%), Positives = 95/264 (35%), Gaps = 12/264 (4%)

Query: 104  MQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAI-TATPSLTVDEKEE 162
            + T   G +T + +G  +       S+    S E   A  + T +  T T S T  E   
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 163  LLTSTNFQPIVEEI-TETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPK 221
            + T+ +    V  I +E T       +  + +TE  E        ++  +T    TT   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE--------TTTASTAGSETTTAS 1197

Query: 222  TEKFEADTDHRTTSFPGAESTAGSEPGSL--TPDKEKPSQMTADNTQAAATKQPLETSEY 279
            T   E  T     S     ST+GSE  +   T  +          T  A       T   
Sbjct: 1198 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1257

Query: 280  TLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVR 339
            T S+EP   SL G+   TVS++ +   A++ +       L   + +    + +   +  R
Sbjct: 1258 TASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTR 1317

Query: 340  TEMSQTAQVSHEGMEGGQPWTEAA 363
            T  ++    S   M  G  +T +A
Sbjct: 1318 TTGTRLTASSSVTMAPGMDFTASA 1341


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 118/524 (22%), Positives = 187/524 (35%), Gaps = 37/524 (7%)

Query: 65  TPQLVVSEDPMMMSAVPSATSLNKAFS-----INKETQPGQAGLMQTERPGVSTPTESGV 119
           TP    SE   + +A    T+++   S         ++   A  M +E   VST   +G 
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVST---AGS 242

Query: 120 PSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEI--T 177
            +     GS      + +S    A    + T T S T  E     T T  +P +     +
Sbjct: 243 ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST-TGSEPTMASTMGS 301

Query: 178 ETTKGFLKYMDNQSFATESQE--GVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
           ETT       +    +T S E   V    S +   +T    TT   T   E  T     S
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGS 361

Query: 236 FPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQP-LETSEYTLSVEPETDSLLGAP 294
               +ST GSE  + + +  + +  + + ++A        ET+  +++    T +     
Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421

Query: 295 EVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGME 354
           E+T +VST V   +  S E  +  + S S        D+E T   TE S+T  V+  G E
Sbjct: 422 EMT-AVSTTVFETTTASTEGSEITIASTS--------DSETTTASTEGSETTTVTTAGSE 472

Query: 355 GGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
               +T  ++         T   T  +   G++ + A T+ S  T  S       ++   
Sbjct: 473 TKTAYTTGSETTTA---SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST- 528

Query: 415 LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT--QEMTTAVQEPDA 472
            + + + T ST  ++      TTVS +  E+      G+ M  + T   E TT   E   
Sbjct: 529 -EGSENTTVSTTGSET-----TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSG 582

Query: 473 TLSMVTQEQVATLELIRDSGKTEEEKED--PSPVSDVPGVTQLSRRWEPLATTISTTVVP 530
           T +  T     T     DS  T     D   +  S     T  +       TT ST    
Sbjct: 583 TTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 531 LSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSIS 574
            +   T   E  M + TG     T   GS  T       E ++S
Sbjct: 643 TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS 686



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 140/608 (23%), Positives = 210/608 (34%), Gaps = 69/608 (11%)

Query: 36   EIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKE 95
            E+  V  E  ++  ++T   E ++V++        S +   M+ V S T         + 
Sbjct: 522  EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV-STTGAETTTDSTEG 580

Query: 96   TQPGQAGLMQTERPGVSTP----TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITA 151
            +    A    +E   VST     T +    +E    S+     +  S  +    T +   
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEG 640

Query: 152  TPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYMD-NQSFATESQEGVG-----LGHS 205
            + + TV   +   T  +       IT T       +    S  T S EG G     +  S
Sbjct: 641  SETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGS 700

Query: 206  PSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNT 265
             ++ V+T    TT   TE  E  T   T S     ST GSE  + T   E     +A  T
Sbjct: 701  ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE--TTTASTEGSETTSASTT 758

Query: 266  QAAATKQPLETSEYTLS--VEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVS 323
             +  T     +SE T++  +  ET         T  VSTA    + +  E  +T + S +
Sbjct: 759  GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 324  RIRTPKL-------------GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLP 370
               T  +             G    T   TE S+T   S EG E     TE+++      
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 371  EG-ETHTG------TALLIAHGNERSPAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFT 422
             G ET T       T      G+E + A T+ S  T  S    +   +     ++T   T
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQV 482
            E ++          T++VS   SE       T    +  E TTA      T ++ T    
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 483  ATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQ 542
             T   I        E  + + VS     T          TT+STT    +  +T T   +
Sbjct: 993  TTTASI--------EGSETTTVSSTGSET----------TTVSTTGTETT--ITSTEGSE 1032

Query: 543  MDTVTGPNEEFTPV--LGSPVTPPGIMVGEPSI-----SPALPALEASSERRTVVPSITR 595
              TVT    E T V   GS  T       E +      S    A  A  E  TV  S + 
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 596  VNTAASYG 603
              TA++ G
Sbjct: 1093 TTTASTAG 1100



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 121/547 (22%), Positives = 183/547 (33%), Gaps = 40/547 (7%)

Query: 47   SDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQT 106
            S KM T   ENS  T   T     +      S    A++     +    T+  +     T
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 107  ERPGVSTP-TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLT 165
            E    +T  TES   +     GS +    S E        T     T + T   +   ++
Sbjct: 859  EGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 166  STNFQPIVE--EITETTKGFLKYMDNQSFATESQEGVGLGH--SPSSYVNTKEMLTTNPK 221
            +T  +      E +ETT    +  +  + +T   E + +    S ++ V T    TT   
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977

Query: 222  TEKFEADT------DHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTA------DNTQAAA 269
            T   E  T      +  T S  G+E+T  S  GS T         T         T    
Sbjct: 978  TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVT 1037

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
            T     T+ YT   E  T S  G+   TVS + +    ++ +D    T   S S   T  
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS 1097

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERS 389
               +E T V    S+T   S EG       +EA  V+    E  T + T      G+E +
Sbjct: 1098 TAGSETTTVYITGSKTTTASTEG-------SEATTVSTTSSETTTASTT------GSEMT 1144

Query: 390  PAFTDQSSFTPTSLM-EDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEAD 448
              FT  S  T  S +  +   S     ++T   TE ++   A      T + S   SE  
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE-- 1202

Query: 449  QLLGNTMKDIITQEMTTA--VQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSD 506
                 T       E  TA       +T S    E      +  +S        +P+  S 
Sbjct: 1203 ----TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSL 1258

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
                T         AT  STTV   +F +T   +  +  +T      T   G+ +T    
Sbjct: 1259 TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSS 1318

Query: 567  MVGEPSI 573
            +   P +
Sbjct: 1319 VTMAPGM 1325



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 108/452 (23%), Positives = 166/452 (36%), Gaps = 59/452 (13%)

Query: 177 TETTKGFLKYMDNQSFATESQEGVGLGHSPSSY----VNTKEMLTTNP----KTEKFEAD 228
           +ETT   +K  +  + +T   E      + S      ++  E+ TT+      T    A 
Sbjct: 23  SETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAG 82

Query: 229 TDHRTTSFPGAE---STAGSEPGSLTPDKEKPSQMTA--DNTQAAATKQPLETSEYTLSV 283
           +   T S  G+E   STAGSE  +++    + + ++A    T   +T     T   T   
Sbjct: 83  SGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 142

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMS 343
           E  T S +G+   T   + +   A++ +     T   + S   TP    +E T V T  S
Sbjct: 143 ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGS 202

Query: 344 QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSL 403
           +T  VS  G E     T  A  A        H+ T      G+E +   T  S  T ++ 
Sbjct: 203 ETTTVSTTGSE-----TTTASTA--------HSETTAASTMGSETTKVSTAGSETTVSTA 249

Query: 404 MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGN--TMKDIITQ 461
             +   +     ++   FTE +K         TT S + +E+ A    G+  TM   +  
Sbjct: 250 GSETTAASTEDSETNTAFTEDSK--------TTTASTTGFETTAASTTGSEPTMASTMGS 301

Query: 462 EMTTA-VQEPDATLSMVTQEQVATL-----ELIRDSGKTEEEKEDPSPVSDVPGVTQLSR 515
           E T A    P+ T       +V T+     E IR S    E     + VS     T  + 
Sbjct: 302 ETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE----TTTVSTTGSETTTAS 357

Query: 516 RWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNE--EFTPV--LGSPVTPPGIMVGEP 571
                 +T STT      E T    E  +T T   E  E T V   GS  T   I   E 
Sbjct: 358 IMGSETSTDSTT----GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 572 SISPALPALEASSERRTVVPSITRVNTAASYG 603
           + +         SE   V  ++    TA++ G
Sbjct: 414 TTT-----CTEGSEMTAVSTTVFETTTASTEG 440



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 115/536 (21%), Positives = 187/536 (34%), Gaps = 46/536 (8%)

Query: 110 GVSTPTESGVPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSLTVDEKEELLTSTN 168
           G  T T S   S   +   S  E   +  +G     ++ A + T + ++   E  +++  
Sbjct: 42  GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG 101

Query: 169 FQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEAD 228
            +     IT T    +  M +++    +        S +    T      +  T  + AD
Sbjct: 102 SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 229 TDHRTTSFPGAE--------------STAGSEPGSLTPDKEKPSQM--TADNTQAAATKQ 272
           ++    S  G+E              STAGSE  +++    + + +  T   T  A+T  
Sbjct: 162 SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 273 PLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGD 332
              T+  T+  E    S  G+ E TVS + +   A++  D   +T     S+  T     
Sbjct: 222 SETTAASTMGSETTKVSTAGS-ETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 333 NEETQVRTEMSQTAQVSHEGMEGGQPWT---EAAQVALGLPEGETHTGTALLIAHGNERS 389
            E T   T  S+    S  G E     T   E  +V+    E  T      + A G+E  
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTT------VFAAGSETI 334

Query: 390 PAFTDQSSFTPTSL--MEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEA 447
            A T  S  T  S    E    SI+    ST   T S     +    ETT + S   SEA
Sbjct: 335 RASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT-TASTEGSEA 393

Query: 448 DQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQ---VATLELIRDSGKTEEEKEDPSPV 504
                 T+    ++  T ++ + + T +     +   V+T      +  TE  +   +  
Sbjct: 394 -----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448

Query: 505 SDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPP 564
           SD    T  +   E   TT++T         T   E    + TG        +GS  T  
Sbjct: 449 SDSETTTASTEGSE--TTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 565 GIMVGEPSI-----SPALPALEASSERRTVVPSITRVNTAASYGLD-QLESEEGQE 614
                E +      S         SE  TV  + +   T ++ GL+    S EG E
Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/334 (19%), Positives = 122/334 (36%), Gaps = 14/334 (4%)

Query: 43   EKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKA-FSINKETQPGQA 101
            E  ++  +++   E ++V++  T   + S +    + V +A S   A ++   ET     
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 102  GLMQTERPGV--STPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDE 159
               +T       S  T +     E    S+     +  S       T+ IT + + T   
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 160  KEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTN 219
            +    T+ +          TT   +  +      T +   +G   + SS   ++   T+ 
Sbjct: 1119 EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 220  PKTEKFEADT---DHRTTSFPGAESTAGSEPGSLT-------PDKEKPSQMTADNTQAAA 269
              +E   A T   +  T S  G+E+T  S  GS T        +   PS   ++ T  A 
Sbjct: 1179 EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-TNTAF 1237

Query: 270  TKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPK 329
                  T   T S+EP   SL G+   TVS++ +   A++ +       L   + +    
Sbjct: 1238 IIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQP 1297

Query: 330  LGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAA 363
            + +   +  RT  ++    S   M  G  +T +A
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 117/544 (21%), Positives = 189/544 (34%), Gaps = 60/544 (11%)

Query: 68   LVVSEDPMMMSAVPSATSLNKAFSINKETQPGQA--GLMQTERPGVSTPTESGVPSAEEV 125
            LV S +   +S  P  TS     S    + P  A    M T  P   +   + +P ++ +
Sbjct: 699  LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758

Query: 126  FGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQ--PIVEEITETTKGF 183
              SS+   +S         +T +  A+ S T  E   +  ST  +  P++  I  +    
Sbjct: 759  LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSIT-- 816

Query: 184  LKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTA 243
                        S E   L  +P   V++   +TT+  TE   + T    TS P +  + 
Sbjct: 817  ---------PVTSPEASTLSTTP---VDSNSPVTTS--TEVSSSPTPAEGTSMPTSTYSE 862

Query: 244  GSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTA 303
            G  P +  P     + + A +  +  +  P++TS       P T+S       T S  T+
Sbjct: 863  GRTPLTSMPVS---TTLVATSAISTLSTTPVDTST------PVTNSTEARSSPTTSEGTS 913

Query: 304  VPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWT-EA 362
            +P ++        T L S+    TP +     T   T +  +  V+        P T E 
Sbjct: 914  MPTSTPGEGS---TPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEG 970

Query: 363  AQVALGLPEGETHTGTALLIAH---GNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTG 419
              +    P   T   T+  ++H    N  +   +     + T L    + S         
Sbjct: 971  TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGT 1030

Query: 420  DFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQ 479
                ST    +       VS ++  S     L  T  D  T   T +     +T +  T 
Sbjct: 1031 SMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTS 1090

Query: 480  EQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTV 539
               +T              E  +P++ VP  T+L    E  A+T+STT V  S  VT + 
Sbjct: 1091 MPTSTYS------------EGSTPLTSVPVSTRLVVSSE--ASTLSTTPVDTSIPVTTST 1136

Query: 540  EEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTV----VPSITR 595
            E      T            P +PP       +  P    L  SSE  T+    V S T+
Sbjct: 1137 EASSSPTTAEGTSI------PTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ 1190

Query: 596  VNTA 599
            V T+
Sbjct: 1191 VATS 1194



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 142/654 (21%), Positives = 230/654 (35%), Gaps = 127/654 (19%)

Query: 68   LVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGL--MQTERPGVSTPTESGVPSAEEV 125
            LVVS +   +S  P  +    A S    + P  A +  M T  PG  +   + +P     
Sbjct: 1171 LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTP 1230

Query: 126  FGSSQPERISPE-----------SGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVE 174
              SS+   +S             +  + +  T   T+ P+ T  E   LLTS      + 
Sbjct: 1231 VASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV 1290

Query: 175  EITET---------TKGFLKYMDNQSFATESQEGVGL-------GHSP--SSYVNTK--- 213
               E          TKG +   +  S +    EG  +       G +P  S  VNT    
Sbjct: 1291 TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350

Query: 214  ----EMLTTNP---------KTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQM 260
                 +L+T P          TE   + T    TS P +  + G+ P +  P    P   
Sbjct: 1351 SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410

Query: 261  TADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLE 320
            +  +T +A    P++TS       P T S       T +   ++P ++    +   T L+
Sbjct: 1411 SEASTLSAT---PVDTS------TPGTTSAEATSSPTTAEGISIPTSTPSEGK---TPLK 1458

Query: 321  SVSRIRTPKLGDNEETQVRTEM-SQTAQVSHEGMEGGQPWTEAAQVALGLP-EGET---- 374
            S+    TP       T   T + S +  V+   +       E   +A+  P EG T    
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518

Query: 375  ----HTGTALLIAHGNERSPAFT-------DQSSFTPTSL----------------MEDM 407
                 T  A    +    +PA T        Q+S +PT+                 +  +
Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSL 1578

Query: 408  KVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQE----- 462
             VS + ++ S  + T ST   D+    +T V+ S   S +    G++M      E     
Sbjct: 1579 PVSTMLVVSSEAN-TLSTTPIDS----KTQVTASTEASSSTTAEGSSMTISTPSEGSPLL 1633

Query: 463  -----MTTAVQEPDA----TLSMVTQEQVATLELIRDSGKTEEEKEDPSP--VSDVPGVT 511
                  TT V  P+A    T  + +   V T   +  S    E    P+         +T
Sbjct: 1634 TSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLT 1693

Query: 512  QLSRRWEPLA----TTISTTVVPLSFEVTPTVEEQMDTVTG---------PNEEFTPVLG 558
             ++ R  P+A    +T+STT V  S  VT + E +    T          P+E  TP+  
Sbjct: 1694 SITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTS 1753

Query: 559  SPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEG 612
             PV+   ++  E S   A P ++ S+   T   + +   TA    +      EG
Sbjct: 1754 IPVSTTPVLSSEASTLSATP-IDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 1806



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 133/596 (22%), Positives = 220/596 (36%), Gaps = 45/596 (7%)

Query: 50   MNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERP 109
            ++T  +  S++++  T  +  S      +   S+ + ++  S+   T PG+     T  P
Sbjct: 872  VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST-PGEGSTPLTSMP 930

Query: 110  GVSTP---TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTS 166
              +TP   +E+   SA  V  +S P   S E+    +  T   T+ P+ T  E    LTS
Sbjct: 931  DSTTPVVSSEARTLSATPV-DTSTPVTTSTEA--TSSPTTAEGTSIPTSTPSEGTTPLTS 987

Query: 167  TNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFE 226
            T     +   +E +      +D+ +  T S E      SP        M T+ P      
Sbjct: 988  TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEA----SSPPPTAEGTSMPTSTPSEGSTP 1043

Query: 227  ADTDHRTTSFPGAE--STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLET----SEYT 280
                  +T+   +   ST  + P   +      SQ ++ +T A  T  P  T    S   
Sbjct: 1044 LTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL 1103

Query: 281  LSVEPETDSLLGAPEVTVS---VSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQ 337
             SV   T  ++ +   T+S   V T++P  ++       T  E  S I T    +     
Sbjct: 1104 TSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTS-IPTSPPSEGTTPL 1162

Query: 338  VRTEMSQTAQVSHEGME-GGQPWTEAAQVALGLPEGE---THTGTALLIAHGNERSPAFT 393
                +S T  VS E       P     QVA          T   T++  +   ERS   T
Sbjct: 1163 ASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLT 1222

Query: 394  DQS-SFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLG 452
                  TP +  E   +S   +  ST   T S + + +    E T   +   SE   LL 
Sbjct: 1223 SMPVRHTPVASSEASTLSTSPVDTST-PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLT 1281

Query: 453  NTMKD---IITQEMTTAVQEP-DATLSMVTQEQVATLELIRD--SGKTEEEKEDPSPVSD 506
            +       + + E +T +  P D    +VT  +V++     +  S  T    E  +P++ 
Sbjct: 1282 SIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTS 1341

Query: 507  VPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTG---------PNEEFTPVL 557
            +P  T L        + +STT V  S  VT + E      T          P+E  TP+ 
Sbjct: 1342 IPVNTTLVA--SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLT 1399

Query: 558  GSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEGQ 613
              PV+   ++  E S   A P ++ S+   T   + +   TA    +      EG+
Sbjct: 1400 SIPVSTTPVVSSEASTLSATP-VDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGK 1454



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 106/551 (19%), Positives = 191/551 (34%), Gaps = 37/551 (6%)

Query: 58   SSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTES 117
            SS  S  +   V +  P+  S+  S++S     +    + P +     T  P  +    S
Sbjct: 525  SSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVS 584

Query: 118  GVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEIT 177
               S      +     ++  S  + +  T   T+ P+ T  E+   +TS +    +   +
Sbjct: 585  SEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASS 644

Query: 178  ETTKGFLKYMDNQSFATESQEGV-------GLGHSPSSYVNTKEMLTTNPKTEKFEADTD 230
            E +      +D+ +  T S E         G     S+Y      LT+ P      A ++
Sbjct: 645  EASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSE 704

Query: 231  HRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSL 290
              T S    +++       +T   E  S  T  +  +  T  P E S    S+ P + +L
Sbjct: 705  ASTLSTTPVDTST-----PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSM-PVSKTL 758

Query: 291  LGAPEV----TVSVSTAVPAASALSDEWDDTKLESVSR-IRTPKLGDNEETQVRTEMS-- 343
            L + E     T  + T+    ++       T  E  S  I TP  G    T +   ++  
Sbjct: 759  LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV 818

Query: 344  ---QTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTP 400
               + + +S   ++   P T + +V+      E  +      + G     +    ++   
Sbjct: 819  TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878

Query: 401  TSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIIT 460
            TS +  +  + V+      + TE+              S     S     + ++   +++
Sbjct: 879  TSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVS 938

Query: 461  QEMTTAVQEPDATLSMVTQEQVATLELIRDSGK---TEEEKEDPSPVSDVPGVTQLSRRW 517
             E  T    P  T + VT    AT       G    T    E  +P++  P    L    
Sbjct: 939  SEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANS 998

Query: 518  EPLATTISTTVVPLSFEVT---------PTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMV 568
            E  A+T+STT V  +  +T         PT E      + P+E  TP+   PV+   +  
Sbjct: 999  E--ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVAS 1056

Query: 569  GEPSISPALPA 579
             E S     PA
Sbjct: 1057 SETSTLSTTPA 1067



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 137/612 (22%), Positives = 228/612 (37%), Gaps = 84/612 (13%)

Query: 58   SSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTES 117
            +S+T + TP    +   +  + V ++T +  +          +   M    P   T   +
Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT 1752

Query: 118  GVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEIT 177
             +P +     SS+   +S         +T +  AT S T  E   + TST    + E +T
Sbjct: 1753 SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST----LSEGMT 1808

Query: 178  ETTKGFLKY--MDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTS 235
              T   + +  + N   +T S   V      +S V T   ++++P      A+     TS
Sbjct: 1809 PLTSTPVSHTLVANSEASTLSTTPV----DSNSPVVTSTAVSSSPT----PAEGTSIATS 1860

Query: 236  FPGAESTA-GSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVE--------PE 286
             P   STA  S P S T      S+    +T  A T  P+ T     S          P 
Sbjct: 1861 TPSEGSTALTSIPVSTT--TVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPT 1918

Query: 287  TDSLLGAPEVT-VSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQT 345
            +    G P +T + VST   A+S +     +T   +++  RTP    ++ +   T    T
Sbjct: 1919 STPREGRPPLTSIPVSTTTVASSEI-----NTLSTTLADTRTPVTTYSQASSSPTTADGT 1973

Query: 346  AQVSHEGMEGGQPWTE--------AAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSS 397
            +  +    EG  P T          +  A  L      T T    +     SP     +S
Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTS 2033

Query: 398  F---TP---TSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESEADQLL 451
                TP   T+ +  M VS   ++ S G+ T ST   D+    +T V+ S   S +    
Sbjct: 2034 IQTSTPSERTTPLAGMPVSTTLVVSSEGN-TLSTTPVDS----KTQVTNSTEASSSATAE 2088

Query: 452  GNTMKDIITQE----------MTTAVQEPDA-TLS---------MVTQEQVATLELIRD- 490
            G++M      E           TT V  P+A TLS         ++T  +V++  +  + 
Sbjct: 2089 GSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEG 2148

Query: 491  -SGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTG- 548
             S +T    +  +P++ +P  T +        +T+STT V  S  VT + E +    T  
Sbjct: 2149 TSMQTSTYSDRRTPLTSMPVSTTVVA--SSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 2206

Query: 549  --------PNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAA 600
                    P+E  TP    PV+   ++  E S   A P ++ S+   T   + +   TA 
Sbjct: 2207 GTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATP-VDTSTPVTTSTEATSSPTTAE 2265

Query: 601  SYGLDQLESEEG 612
               +      EG
Sbjct: 2266 GTSIPTSTLSEG 2277



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 129/595 (21%), Positives = 217/595 (36%), Gaps = 80/595 (13%)

Query: 58   SSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTES 117
            +S+    TP  V S +   +S  P  TS+    S    + P  A    T  P +STP+E 
Sbjct: 2872 TSIPVSTTP--VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE--GTSMP-ISTPSEV 2926

Query: 118  GVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEIT 177
              P    +  S+ P   S  S L+    T   T TP  T  E     T+     +     
Sbjct: 2927 STPLTS-ILVSTVPVAGSEASTLST---TPVDTRTPVTTSAEASSSPTTAEGTSMPISTP 2982

Query: 178  ETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFP 237
               +  L  M   +    S E   L  +P+   +T   +TT+  TE   + T    T  P
Sbjct: 2983 GERRTPLTSMSVSTMPVASSEASTLSRTPA---DTSTPVTTS--TEASSSPTTAEGTGIP 3037

Query: 238  GAESTAGSEPGSLTPDKEKP-----------------------SQMTADNTQAAATKQPL 274
             +  + GS P +  P    P                       +++++  T A  T  P+
Sbjct: 3038 ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPI 3097

Query: 275  ET--------SEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSR-I 325
             T        +   +S  P T S +     T  V T+ P  ++       T  E  S   
Sbjct: 3098 STYSEGSTPLTGVPVSTTPVTSSAISTLSTT-PVDTSTPVTTSTEAHSSPTTSEGTSMPT 3156

Query: 326  RTPKLGDNEETQVRTEM-----SQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTAL 380
             TP  G    T +         S+ + +S   ++   P T + +         T  GT++
Sbjct: 3157 STPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT----SSTTAEGTSI 3212

Query: 381  LIAHGNE-RSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS 439
              +  +E  +P  +   S TP +  E   +S   +  +T   T ST+ + +    E T  
Sbjct: 3213 PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNT-PLTTSTEASSSPPTAEGTSM 3271

Query: 440  VSVYESEADQLLGN---TMKDIITQEMTTAVQEP-DATLSMVTQEQVATLELIRD--SGK 493
             +   SE    L +   +   + + E +T    P D +  + T  Q ++   I D  S  
Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331

Query: 494  TEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVT------ 547
            T    E  +P++++   T      E  A+T+STT V  S  VT + E  +   T      
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSE--ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSI 3389

Query: 548  ---GPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTA 599
                P+E  TP+   PV+   ++  E +     P      +  T+V + T  +++
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPV-----DSNTLVTTSTEASSS 3439



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 136/596 (22%), Positives = 212/596 (35%), Gaps = 91/596 (15%)

Query: 60  VTSKQTPQLVVSEDPMMMSAV-PSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESG 118
           V S   PQ    +D  +  AV      +++   +N++ Q     L Q  R G +  T +G
Sbjct: 15  VLSLLPPQAAAEQDLSVNRAVWDGGGCISQGDVLNRQCQQ----LSQHVRTGSAANTATG 70

Query: 119 VPSAEEVFG------SSQPERISPESGLAKAMLTIAITA-TPSLTVDEKEELLTSTNFQP 171
             S   V        S+ PE  S ES +      ++ T  TP+ +    E    ST   P
Sbjct: 71  TTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFP 130

Query: 172 IVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDH 231
              E  +T+        +   +T S+E +    S  ++V+T  +    P  E + + T  
Sbjct: 131 SSTE--DTSSPTTPEGTDVPMSTPSEESIS---STMAFVSTAPL----PSFEAYTSLTYK 181

Query: 232 RTTSFPGAESTAGSE----PGSLTPDKEKPSQMTADNTQAAATKQPLETSE----YTLSV 283
              S P   ST  S     P S T  K   S+ +   T   A+   + +SE     T  V
Sbjct: 182 VDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPV 241

Query: 284 EPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKL------------ESVSRIRTPKLG 331
           E  T   + A   +   +   P+ S  +     T L               S + T    
Sbjct: 242 EISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAA 301

Query: 332 DNEETQVRTEMSQTAQVSHEGM--------EGGQPWTEAAQVALGLPEGETHT------G 377
            N      TE S +   + EG         EG  P T      + +   E  T       
Sbjct: 302 TNIPVITSTEASSSPTTA-EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVD 360

Query: 378 TALLIAHGNERS--PAFTDQSSFTPTSLME------DMKVSIVNLLQSTGDFTESTKEND 429
           T+ L+    E S  P   + +S   ++L E      +M VS + L+ S+   T ST   D
Sbjct: 361 TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTI-LVASSEASTTSTIPVD 419

Query: 430 ALFFLETTVSVSVYESEADQLL--------GNTMKDIITQEMTTAVQEPDATLSMV---T 478
           +  F+ T    S   + A+           G+T    +    T       + LS     +
Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479

Query: 479 QEQVATLELIRDSGKTEEEKEDPS--PVSDVPGVTQLSRRWEPLAT----TISTTVVPLS 532
           + QV T      S  T E    P+  P      +T +S    P+A+    T+STT V  S
Sbjct: 480 KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS 539

Query: 533 FEVTPTVEEQMDTVTG---------PNEEFTPVLGSPVTPPGIMVGEPSISPALPA 579
             VT + E    + T          P+E  TP+   PV+   ++  E S +   PA
Sbjct: 540 TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA 595



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 124/589 (21%), Positives = 214/589 (36%), Gaps = 85/589 (14%)

Query: 56   ENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPT 115
            +++S+      ++  S   +++S +P A+S     S    T P     + T     ST T
Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLS----TTPVDTRTLVT----TSTGT 2670

Query: 116  ESGVPSAEEVFGSSQP-----ERISPESGLAKAMLTIAITATPSLT---VDEKEELLTST 167
             S   +AE   GSS P     ER +P + +  +   +A +   +L+   VD    + TS 
Sbjct: 2671 SSSPTTAE---GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSA 2727

Query: 168  NFQPIVEEITETTKGFLKYMDNQSFATESQEG-VGLGHSPSSYVNTKEMLTTNPKTEKFE 226
                       T+       D  +  T      + +  S +S V+T  + T+ P T   E
Sbjct: 2728 EASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE 2787

Query: 227  ADTDHRT---TSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSV 283
            A +   T   TS P +  +  S P +  P    P    A +     +  P++TS    + 
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTP---VASSEAGTLSTTPVDTSTPVTTS 2844

Query: 284  EPETDSLLGAPEVTVSVSTA--------------VPAASALSDEWDDTKLESVSRIRTPK 329
               + S   A  + V +STA               P AS+ +     T +++   + T  
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTST 2904

Query: 330  LGDNEET-------------QVRTEM------------SQTAQVSHEGMEGGQPWTEAAQ 364
             G +  T             +V T +            S+ + +S   ++   P T +A+
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964

Query: 365  VALGLPEGETHTGTALLIAHGNERSPAFTDQS-SFTPTSLMEDMKVSIVNLLQSTGDFTE 423
             +       T  GT++ I+   ER    T  S S  P +  E   +S      ST   T 
Sbjct: 2965 AS---SSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTS 3021

Query: 424  STKENDALFFLETTVSVSVYESEADQLLG---NTMKDIITQEMTTAVQEPDATLSMVTQE 480
            +   +       T + +S     +  L     +T    I +  T +    D+   +VT  
Sbjct: 3022 TEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTST 3081

Query: 481  QVATLELIRD--SGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPT 538
            +V++     +  S       E  +P++ VP  T  +       +T+STT V  S  VT +
Sbjct: 3082 EVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST--TPVTSSAISTLSTTPVDTSTPVTTS 3139

Query: 539  VEEQMDTVTG---------PNEEFTPVLGSPVTPPGIMVGEPSISPALP 578
             E      T          P+E  TP+   PV+   ++  E S   A P
Sbjct: 3140 TEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 133/590 (22%), Positives = 215/590 (36%), Gaps = 74/590 (12%)

Query: 44   KGQSDKMNTDDLENSSVTSKQTPQL-VVSEDPMMMSAVPSATSLNKAFSINKETQPGQAG 102
            +G S +++T    ++ +TS     L V S +   +S     TS+    S    + P  A 
Sbjct: 2737 EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAE 2796

Query: 103  LMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEE 162
            +  T  P  STP+E+  P       +S P   +P +      L+     T +      + 
Sbjct: 2797 V--TSMP-TSTPSETSTPL------TSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847

Query: 163  LLTSTNFQPIVEEITETTKG--FLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNP 220
              + T  + IV  I+  ++G   L  +   +    S E   L  +P   V+T   +TT+ 
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP---VDTSIPVTTS- 2903

Query: 221  KTEKFEADTDHRTTSFP----------------GAESTAGSEPGSL--TP-DKEKP---- 257
             TE   + T    TS P                     AGSE  +L  TP D   P    
Sbjct: 2904 -TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTS 2962

Query: 258  SQMTADNTQAAATKQPLET--------SEYTLSVEPETDSLLGAPEVTVSVSTAVPAASA 309
            ++ ++  T A  T  P+ T        +  ++S  P   S       T +  T+ P  ++
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPA-DTSTPVTTS 3021

Query: 310  LSDEWDDTKLESVS-RIRTPKLGDNEETQVRTEMSQTA-----QVSHEGMEGGQPWTEAA 363
                   T  E     I TP  G    T +    +  A      +S   ++   P   + 
Sbjct: 3022 TEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTST 3081

Query: 364  QVALGLPEGETHTGTALLIAHGNERSPAFTDQS-SFTPTSLMEDMKVSIVNLLQSTGDFT 422
            +V+      E   GT++ I+  +E S   T    S TP +      +S   +  ST   T
Sbjct: 3082 EVSSSPTPAE---GTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTST-PVT 3137

Query: 423  ESTKENDALFFLETTVSVSVYESEADQLLG----NTMKDIITQEMTTAVQEPDATLSMVT 478
             ST+ + +    E T   +   SE    L     +TM  +++ E +T    P  T + VT
Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTML-VVSSEDSTLSATPVDTSTPVT 3196

Query: 479  QEQVATLELIRD--SGKTEEEKEDPSPVSDVP--GVTQLSRRWEPLATTISTTVVPLSFE 534
                AT     +  S  T    E  +P++ VP       S     L+TT   +  PL+  
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256

Query: 535  VT-----PTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPA 579
                   PT E      + P+E  TP+   PV+   +   E S     PA
Sbjct: 3257 TEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA 3306



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 126/593 (21%), Positives = 198/593 (33%), Gaps = 88/593 (14%)

Query: 38   AHVHAEKGQSDKMNTDDLENSSVTSKQTP---QLVVSEDPMMMSAVPSATSLNKAFSINK 94
            AH      +   M T      S      P    LVVS +   +SA P  TS     S   
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201

Query: 95   ETQPGQAGL-MQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATP 153
             +     G  + T  P       + VP +     SS+   +S     +   LT +  A+ 
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASS 3261

Query: 154  SLTVDEKEELLTSTNFQ---PIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYV 210
            S    E   + TST  +   P+      TT                     +  S +S +
Sbjct: 3262 SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTT--------------------VASSETSTL 3301

Query: 211  NTKEMLTTNPKTEKFEADTDHRT---TSFPGAESTAGSEPGSLTPDKEKP---SQMTADN 264
            +T    T+ P T   +A +       TS P +  + GS P +       P   S+ +  +
Sbjct: 3302 STTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLS 3361

Query: 265  TQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSR 324
            T    T  P+ TS    S+ P T      P  + S  T   A+  +S          V+ 
Sbjct: 3362 TTPVDTSTPVTTSTEA-SLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT--PVVSSEVNT 3418

Query: 325  IRTPKLGDNEETQVRTEMSQTAQVSHEGM--------EGGQPWT--------EAAQVALG 368
            + T  +  N      TE S +  ++ EG         EG  P +         A+  A  
Sbjct: 3419 LSTTPVDSNTLVTTSTEASSSPTIA-EGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST 3477

Query: 369  LPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKEN 428
            L      T T +  +     SP   + +S  PTS   +    + N+  ST     S    
Sbjct: 3478 LSTTPVDTSTPVTTSSPTNSSPTTAEVTSM-PTSTAGEGSTPLTNMPVSTTPVASS---- 3532

Query: 429  DALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELI 488
            +A     T V  + + + + Q   +     +T    +   E  ++L         T  L+
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSL---------TTMLL 3583

Query: 489  RDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTG 548
              +  T  E   PS     P V     R  P+ T+  +   P   EV   +   M T   
Sbjct: 3584 SSTYVTSSEASTPS----TPSVD----RSTPVTTSTQSNSTPTPPEV---ITLPMST--- 3629

Query: 549  PNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAAS 601
            P+E  TP+   PV+   + + E   +  LP         T  P IT    ++S
Sbjct: 3630 PSEVSTPLTIMPVSTTSVTISEAGTASTLPV-------DTSTPVITSTQVSSS 3675



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 127/603 (21%), Positives = 214/603 (35%), Gaps = 60/603 (9%)

Query: 18   LFSVATQCLAFPKIERRREIAHVHAEKGQSDKMNTDDLENSSVTSKQTPQL----VVSED 73
            L + +T+  + P I     +      +G S  ++   L  + V S +   L    V +  
Sbjct: 3429 LVTTSTEASSSPTIAEGTSLPTSTTSEG-STPLSIMPLSTTPVASSEASTLSTTPVDTST 3487

Query: 74   PMMMSAVPSATSLNKAFSINKETQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPER 133
            P+  S+  +++      +    +  G+     T  P  +TP  S   S            
Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547

Query: 134  ISPESGLAKAMLTIAIT----ATPSLTVDEKEELLTSTNFQPIVEEITETTKGFLKYM-- 187
            ++  S  + +  T+ +T    +TPS        +L S+ +    E  T +T    +    
Sbjct: 3548 VTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPV 3607

Query: 188  --DNQSFATESQ-EGVGLGHSPSSYVNTKEML-----TTNPKTEKFEADTDHRTTSFPGA 239
                QS +T +  E + L  S  S V+T   +     T+   +E   A T    TS P  
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVI 3667

Query: 240  ESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVS 299
             ST  S    +TP+       T        T  P+ T+  T S      S L  P V  S
Sbjct: 3668 TSTQVSS-SPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSS----EGSTLSTPSVVTS 3722

Query: 300  --VSTAVPAASALSDEWDDTKLESVSRIRTPKLGDN--EETQVRTEMSQTAQVSHEGMEG 355
              V+T+  A S+ S   D T +     +    LG      T   T   +++  S   +  
Sbjct: 3723 TPVTTSTEAISS-SATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781

Query: 356  GQPWTEAAQVALGLPEGETHTGTALL-IAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNL 414
                T A++   G     T  GT  + ++  +ERS            +L+  + +S +++
Sbjct: 3782 SMSMTTASE---GSSSPTTLEGTTTMPMSTTSERS------------TLLTTVLISPISV 3826

Query: 415  LQSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATL 474
            +  +   T ST   D    L T+     +   A+     T++  IT E +T    P  TL
Sbjct: 3827 MSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEV---TTIRISITSERST----PLTTL 3879

Query: 475  SMVTQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFE 534
             + T     TL                +  +  P     S    P+ATTIS +V+     
Sbjct: 3880 LVST-----TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGST 3934

Query: 535  VTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGE---PSISPALPALEASSERRTVVP 591
               T+      VT    +  P     V+ P I   E   PS S +      S+ +    P
Sbjct: 3935 PGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTP 3994

Query: 592  SIT 594
            ++T
Sbjct: 3995 AMT 3997



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 90/409 (22%), Positives = 129/409 (31%), Gaps = 61/409 (14%)

Query: 207  SSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQ 266
            SS   T E  TT P +   E  T   T         + SE  +L+      S     +T+
Sbjct: 3792 SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTK 3851

Query: 267  AAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIR 326
            A +   P E +   +S+  E  + L    V+ ++ T+ P AS  S               
Sbjct: 3852 AGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS--------------- 3896

Query: 327  TPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGN 386
            TP L  +      T+ + T  +         P      V++ + EG T  GT + I    
Sbjct: 3897 TPPLDTSTTFTPSTDTASTPTI---------PVATTISVSV-ITEGST-PGTTIFIPS-- 3943

Query: 387  ERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVSVSVYESE 446
                  T  +S T              ++ ST   T ST  +       TT S S     
Sbjct: 3944 ------TPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSS------STTTSFS----- 3986

Query: 447  ADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSD 506
                   T K+  T  MTTA      T+S        T      S  T      P   + 
Sbjct: 3987 -------TTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039

Query: 507  VP--GVTQLSRRWEP---LATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPV 561
            V    VT  S    P    + TI  T  P      PT      TV   N E    + +  
Sbjct: 4040 VTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTV---NPEAVTTMTTRT 4096

Query: 562  TPPGIMVGEPSI-SPALPALEASSERRTVVPSITRVNTAASYGLDQLES 609
             P       P++ + A+P         T  P++ R  T    G     S
Sbjct: 4097 KPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTAS 4145


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 111/466 (23%), Positives = 166/466 (35%), Gaps = 27/466 (5%)

Query: 115  TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVE 174
            T SG+      F  S     S ++GL  A LT A     S T        T T   P   
Sbjct: 1349 TTSGLTEESTAFPGSPA---STQTGLP-ATLTTADLGEESTTFPSSSGS-TGTKLSPA-- 1401

Query: 175  EITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTT 234
                TT G +        +  S E   L  SP++   +++  T        +A     TT
Sbjct: 1402 --RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 1459

Query: 235  SFPGAE---STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETS-EYTLSVEPETDSL 290
            +  G     ST+ S+PGS        S  T+D +Q   T    + S E TLS    T S 
Sbjct: 1460 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1519

Query: 291  LGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSH 350
            LG    T   S      + L D+   + L   S       G    T   T  S T+    
Sbjct: 1520 LGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--TPASSTSAGLQ 1577

Query: 351  EGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVS 410
            E     Q W  ++      P G T     +   + +  S   T   S + T+L    + +
Sbjct: 1578 EESTTFQSWPSSSDTTPS-PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 1636

Query: 411  IVNLLQ-STGDFTESTKENDALFFLETTVS-VSVYESEADQLLGNTMKDIITQEMTT--- 465
             V+    +TG     T+   ++   E T S +S   +E   L G+T    ++++ TT   
Sbjct: 1637 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 1696

Query: 466  AVQEPDATLSMVTQEQVATLELIRDS----GKTEEEKEDPSPVSDVPGVTQLSRRWEPLA 521
            + + PD TLS  +       E    S    G T       S  + +PGV+Q S       
Sbjct: 1697 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS--TTMPGVSQESTASHSSP 1754

Query: 522  TTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIM 567
             +  TT+ P S   +    E     + P    T +L    T  G++
Sbjct: 1755 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLL 1800



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 110/469 (23%), Positives = 171/469 (36%), Gaps = 33/469 (7%)

Query: 115  TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVE 174
            T SG+      F  S     S ++GL  A LT A     S T        T T   P   
Sbjct: 2906 TTSGLTEESTAFPGSPA---STQTGLP-ATLTTADLGEESTTFPSSSGS-TGTTLSPA-- 2958

Query: 175  EITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTT 234
                TT G +        +  S E   L  SP++   +++  T        +A     TT
Sbjct: 2959 --RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 3016

Query: 235  SFPGAE---STAGSEPGSLT----PDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPET 287
            +  G     ST+ S+PGS      PD    S ++ + T + +++    ++E TLS    T
Sbjct: 3017 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG---STEATLSPGSTT 3073

Query: 288  DSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQ 347
             S LG    T   S      + L D+   + L   S       G    T   T  S T+ 
Sbjct: 3074 ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--TPASSTSA 3131

Query: 348  VSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDM 407
               E     Q W  ++      P G T     +   + +  S   T   S + T+L    
Sbjct: 3132 GLQEESTTFQSWPSSSDTTPS-PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 3190

Query: 408  KVSIVNLLQ-STGDFTESTKENDALFFLETTVS-VSVYESEADQLLGNTMKDIITQEMTT 465
            + + V+    +TG     T+   ++   E T S +S   +E   L G+T    ++++ TT
Sbjct: 3191 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 3250

Query: 466  ---AVQEPDATLSMVTQEQVATLELIRDS----GKTEEEKEDPSPVSDVPGVTQLSRRWE 518
               + + PD TLS  +       E    S    G T       S  + +PGV+Q S    
Sbjct: 3251 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS--TTMPGVSQESTASH 3308

Query: 519  PLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIM 567
                +  TT+ P S   +    E     +GP    T +L    T  G++
Sbjct: 3309 SSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLL 3357



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 105/463 (22%), Positives = 158/463 (34%), Gaps = 21/463 (4%)

Query: 115  TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVE 174
            T SG+      F  S     S ++GL  A LT A     S T        T T   P   
Sbjct: 3989 TTSGLTEESTAFPGSPA---STQTGLP-ATLTTADLGEESTTFPSSSGS-TGTKLSPA-- 4041

Query: 175  EITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTT 234
                TT G +        +  S E   L  SP++   +++  T        +A     TT
Sbjct: 4042 --RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 4099

Query: 235  SFPGAE---STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETS-EYTLSVEPETDSL 290
            +  G     ST+ S+PGS        S  T+  +Q   T    + S E TLS    T S 
Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159

Query: 291  LGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSH 350
            LG    T   S      + L D+   + L   S       G    T   T  S T+    
Sbjct: 4160 LGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--TPASSTSTGLQ 4217

Query: 351  EGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVS 410
            E     Q W  ++      P             H    S   T  S+ + T    +   +
Sbjct: 4218 EESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 4277

Query: 411  IVNLLQSTGDFTESTKENDALFFLETTVS-VSVYESEADQLLGNTMKDIITQEMTT---A 466
            + +   +TG     T+   ++   E T S +S   +E   L G+T    ++++ TT   +
Sbjct: 4278 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 4337

Query: 467  VQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSD--VPGVTQLSRRWEPLATTI 524
             + PD TLS  +       E    S          +  S   +PGV+Q S        + 
Sbjct: 4338 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGST 4397

Query: 525  STTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIM 567
             TT+ P S   +    E     + P    T +L    T  G++
Sbjct: 4398 DTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLL 4440



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 112/520 (21%), Positives = 175/520 (33%), Gaps = 72/520 (13%)

Query: 98   PGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTV 157
            P +       RP  STPT     S+  +  S +   +    G     L    +AT  L  
Sbjct: 3160 PVEVSTTYHSRPS-STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 3218

Query: 158  DEKEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLT 217
            +     ++S + +      + TT G             S++      SP S   T    +
Sbjct: 3219 EPTTSPISSGSTETTALPGSTTTAGL------------SEKSTTFYSSPRSPDTTLSPAS 3266

Query: 218  TNPKTEKFEADTDH------RTTSFPGA--------ESTAG-SEPGS----LTPDKEKPS 258
            T       E+ T H       TT+FPG+        ESTA  S PGS    L+P     S
Sbjct: 3267 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 3326

Query: 259  QMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVP-----AASALSDE 313
             +  ++T   +     ET   TL  +  T S L      V  ST  P      A + + +
Sbjct: 3327 SLGPESTTFHSGPGSTET---TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 3383

Query: 314  WDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTE--AAQVALGLPE 371
             + T  +S    +         T    E+S T+     G     P T   A+   LG  E
Sbjct: 3384 GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSH----GSPSSTPTTHFSASSTTLGRSE 3439

Query: 372  GETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQ-STGDFTESTKENDA 430
             E+ T  +  +A     SPA +  S     S            +     D T    E   
Sbjct: 3440 -ESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEEST 3498

Query: 431  LFFLETTVSVSVYESEADQLL----------GNTMKDIITQEMTTAVQEPDATLSMVTQE 480
                 TT ++S   S    L+          G+T         TT+ +  ++T S  +Q+
Sbjct: 3499 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 3558

Query: 481  QVATLEL-IRDSGKTEEEKEDPSPVSD-------------VPGVTQLSRRWEPLATTIST 526
               T+ L  R +      +   SP+S               PG+++ S  +     + +T
Sbjct: 3559 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 3618

Query: 527  TVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
            T+ P S   +   EE   + + P    T       T PG+
Sbjct: 3619 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 3658



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 114/519 (21%), Positives = 178/519 (34%), Gaps = 60/519 (11%)

Query: 96   TQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERIS-PESGLAKAMLTIAITATPS 154
            T PG +    T      +PT +  P++    G  +    S  + G   + ++ A T TP 
Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935

Query: 155  L-----TVDEKEELLTSTNFQP-----IVEEITETTKGFLKYMDNQSFATESQEGVGLGH 204
            L     TV       T T   P      V     TT        + +  TE     GL  
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995

Query: 205  SPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSE-----------PGSLTPD 253
              +++  +     T        AD    +T+FP +  + G++            G  TP 
Sbjct: 3996 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 4055

Query: 254  KEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDE 313
            +  PS         + T   L     T    P       +P+ T+S +T    +S +S+E
Sbjct: 4056 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR------SPDATLSPATT--TSSGVSEE 4107

Query: 314  WDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGE 373
               T         T    D+  T   + +SQ    SH      Q  TEA      L  G 
Sbjct: 4108 -SSTSHSQPGSTHTTAFPDSTTT---SGLSQEPTTSH----SSQGSTEAT-----LSPGS 4154

Query: 374  THTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFF 433
            T T ++L      ++S  F      T T+L+ D  ++   +  ST   + +   +  L  
Sbjct: 4155 T-TASSL-----GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 4208

Query: 434  LETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGK 493
              +T +    ES   Q   ++     +   TTAV    +T          T      S  
Sbjct: 4209 ASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTH-FSASST 4267

Query: 494  TEEEKEDPSPVSDVPGVTQLSRRWEPLATTI---STTVVPLSFEVTPTVEEQMDTVT-GP 549
            T    E+ + V   PG T  +      AT++     T  P+S   T T      T T G 
Sbjct: 4268 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL 4327

Query: 550  NEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRT 588
            +E+ T    SP +P      + ++SPA       SE  T
Sbjct: 4328 SEKSTTFYSSPRSP------DTTLSPASTTSSGVSEEST 4360



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 118/529 (22%), Positives = 184/529 (34%), Gaps = 80/529 (15%)

Query: 96   TQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERIS-PESGLAKAMLTIAITATPS 154
            T PG +    T      +PT +  P++    G  +    S  + G   + ++ A T TP 
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 1295

Query: 155  L-----TVDEKEELLTSTNFQP-----IVEEITETTKGFLKYMDNQSFATESQEGVGLGH 204
            L     TV       T T   P      V     TT        + +  TE     GL  
Sbjct: 1296 LSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 1355

Query: 205  SPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSE-----------PGSLTPD 253
              +++  +     T        AD    +T+FP +  + G++            G  TP 
Sbjct: 1356 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 1415

Query: 254  KEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDE 313
            +  PS         + T   L     T    P       +P+ T+S +T    +S +S+E
Sbjct: 1416 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR------SPDATLSPATT--TSSGVSEE 1467

Query: 314  WDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGE 373
               T         T    D+  T   +++SQ    SH      Q  TEA      L  G 
Sbjct: 1468 -SSTSHSQPGSTHTTAFPDSTTT---SDLSQEPTTSH----SSQGSTEAT-----LSPGS 1514

Query: 374  THTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFF 433
            T T ++L      ++S  F      T T+L+ D  +       ++G    ST  + +   
Sbjct: 1515 T-TASSL-----GQQSTTFHSSPGDTETTLLPDDTI-------TSGLVEASTPTHSSTGS 1561

Query: 434  LETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRD--- 490
            L TT++ +   S   Q    T +   +   TT    P  T + V   +V+T    R    
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP-SPPGTTAAPV---EVSTTYHSRPSST 1617

Query: 491  -------SGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTI---STTVVPLSFEVTPTVE 540
                   S  T    E+ + V   PG T  +      AT++     T  P+S   T T  
Sbjct: 1618 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 1677

Query: 541  EQMDTVT-GPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRT 588
                T T G +E+ T    SP +P      + ++SPA       SE  T
Sbjct: 1678 LPGSTTTAGLSEKSTTFYSSPRSP------DTTLSPASTTSSGVSEEST 1720



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 112/520 (21%), Positives = 177/520 (34%), Gaps = 72/520 (13%)

Query: 98   PGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTV 157
            P +       RP  STPT     S+  +  S +   +    G     L    +AT  L  
Sbjct: 1603 PVEVSTTYHSRPS-STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 1661

Query: 158  DEKEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLT 217
            +     ++S + +      + TT G             S++      SP S   T    +
Sbjct: 1662 EPTTSPISSGSTETTALPGSTTTAGL------------SEKSTTFYSSPRSPDTTLSPAS 1709

Query: 218  TNPKTEKFEADTDH------RTTSFPGA--------ESTAG-SEPGS----LTPDKEKPS 258
            T       E+ T H       TT+FPG+        ESTA  S PGS    L+P     S
Sbjct: 1710 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769

Query: 259  QMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVP-----AASALSDE 313
             +  ++T   ++    ET   TL  +  T S L      V  ST  P      A + + +
Sbjct: 1770 SLGPESTTFHSSPGSTET---TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 1826

Query: 314  WDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTE--AAQVALGLPE 371
             + T  +S    +         T    E+S T+     G     P T   A+   LG  E
Sbjct: 1827 GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH----GSPSSTPTTHFSASSTTLGRSE 1882

Query: 372  GETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTK-ENDA 430
             E+ T  +  +A     SPA +  S     S            +      T S + E   
Sbjct: 1883 -ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1941

Query: 431  LFFLETTVSVSVYESEADQLL----------GNTMKDIITQEMTTAVQEPDATLSMVTQE 480
                 TT ++S   S    L+          G+T         TT+ +  ++T S  +Q+
Sbjct: 1942 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 2001

Query: 481  QVATLEL-IRDSGKTEEEKEDPSPVSD-------------VPGVTQLSRRWEPLATTIST 526
               T+ L  R +      +   SP+S               PG+++ S  +     + +T
Sbjct: 2002 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 2061

Query: 527  TVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
            T+ P S   +   EE   + + P    T       T PG+
Sbjct: 2062 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 2101



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 120/533 (22%), Positives = 183/533 (34%), Gaps = 88/533 (16%)

Query: 96   TQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERIS-PESGLAKAMLTIAITATPS 154
            T PG +    T      +PT +  P++    G  +    S  + G   + ++ A T TP 
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2852

Query: 155  LTVDEKEELLTSTNFQPIVEEIT--------------ETTKGFLKYMDNQSFATESQEGV 200
            L+    EE  T  +  P   E T               TT        + +  TE     
Sbjct: 2853 LS----EESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2908

Query: 201  GLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPG-----------AESTAGSEPGS 249
            GL    +++  +     T        AD    +T+FP            A ST     G 
Sbjct: 2909 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2968

Query: 250  LTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASA 309
             TP +  PS         + T   L     T    P       +P+ T+S +T    +S 
Sbjct: 2969 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR------SPDATLSPATT--TSSG 3020

Query: 310  LSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGL 369
            +S+E   T         T    D+  T   + +SQ    SH      Q  TEA      L
Sbjct: 3021 VSEE-SSTSHSQPGSTHTTAFPDSTTT---SGLSQEPTASH----SSQGSTEAT-----L 3067

Query: 370  PEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKEND 429
              G T T ++L      ++S  F      T T+L+ D  +       ++G    ST  + 
Sbjct: 3068 SPGST-TASSL-----GQQSTTFHSSPGDTETTLLPDDTI-------TSGLVEASTPTHS 3114

Query: 430  ALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIR 489
            +   L TT++ +   S   Q    T +   +   TT    P  T + V   +V+T    R
Sbjct: 3115 STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP-SPPGTTAAPV---EVSTTYHSR 3170

Query: 490  D----------SGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTI---STTVVPLSFEVT 536
                       S  T    E+ + V   PG T  +      AT++     T  P+S   T
Sbjct: 3171 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 3230

Query: 537  PTVEEQMDTVT-GPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRT 588
             T      T T G +E+ T    SP +P      + ++SPA       SE  T
Sbjct: 3231 ETTALPGSTTTAGLSEKSTTFYSSPRSP------DTTLSPASTTSSGVSEEST 3277



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 118/564 (20%), Positives = 199/564 (35%), Gaps = 56/564 (9%)

Query: 41   HAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQ 100
            H+  G +  M+  + + +S   +++     S    + SA PS TS       +  + PG 
Sbjct: 3473 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSYHSSPG- 3530

Query: 101  AGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEK 160
                       ST T +  P +    G S+    S  S  A   + +   +T S+     
Sbjct: 3531 -----------STAT-THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV----- 3573

Query: 161  EELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNP 220
              LL  +   PI     ETT        + +    S++      SP S   T    +T  
Sbjct: 3574 --LLGESTTSPISSGSMETTA----LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 3627

Query: 221  KTEKFEADTDH------RTTSFPGAESTAG---------SEPGSLTPDKEKPSQMTADNT 265
                 E+ T H       TT+FP + +T G         S PGS        S  T+ ++
Sbjct: 3628 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSS 3687

Query: 266  QAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRI 325
            Q + T      S  T      T +L    E T   S+  P ++  +   D T    +   
Sbjct: 3688 QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSS--PGSTHTTLFPDSTTSSGIVEA 3745

Query: 326  RTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHG 385
             T     +     RT +S  +  S  G++G     +    +         T TA +    
Sbjct: 3746 STRV--HSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 3802

Query: 386  N-ERSPAFTDQSSF--TPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS-VS 441
               RSP  T  + F  + T+     K +I +        T S+  +      E+T S +S
Sbjct: 3803 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 3862

Query: 442  VYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEE---- 497
               +E   L G+T    +++  TT    P +  + ++   + +L +  +S  +  +    
Sbjct: 3863 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 3922

Query: 498  KEDPSPVS-DVPGVTQLSRR-WEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTP 555
                SP S   PG+++ S   +     +  TTV P S   +   EE     + P    T 
Sbjct: 3923 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTT 3982

Query: 556  VLGSPVTPPGIMVGEPSISPALPA 579
            +     T  G +  E +  P  PA
Sbjct: 3983 LFTEDSTTSG-LTEESTAFPGSPA 4005



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 131/611 (21%), Positives = 203/611 (33%), Gaps = 71/611 (11%)

Query: 48   DKMNTDDLENSSVTSKQTP-----QLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAG 102
            D   T  L   S TS  +P      L+ +      S+  S TS + + S +    PG   
Sbjct: 3651 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTT 3710

Query: 103  LMQTERPGVSTPTESG------VPSAEEVFGSSQPE-RISPESGLAKAMLTIAITATPSL 155
             +   +   +  +  G       P +    G  +   R+   +G  +  L+ A + +P L
Sbjct: 3711 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 3770

Query: 156  ----TVDEKEELLTSTNFQPIVEEITETTKGFLKYMDNQSFATES--QEGVGLGHSPSSY 209
                T  +     T T   P         +    +    S  T          GHS  S 
Sbjct: 3771 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 3830

Query: 210  VNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGS-----LTPDKEKPSQMTADN 264
            +       ++P        + H TTS  G  +T+   PGS     L      P    A  
Sbjct: 3831 I-----FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 3885

Query: 265  TQAAATKQPLET----SEYTLSVEPETDSLLGAPEVTVS-VSTAVPAASALSDEWDDTKL 319
            T  ++ + P  T    S  +L V  E+ +    P  T S VS A      LS+E      
Sbjct: 3886 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 3945

Query: 320  ESVSRIRTPKLGDNEETQVRTE----------MSQTAQVSHEGMEGGQPWTEAAQVALGL 369
             S     T     +  T VR E           + T   + +    G   TE +    G 
Sbjct: 3946 SSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGS 4003

Query: 370  PEGETHTG--TALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQST-GDFTESTK 426
            P   T TG    L  A   E S  F   S  T T L      +   + +ST    + S+ 
Sbjct: 4004 P-ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSST 4062

Query: 427  ENDALFFLETTVSVS-----VYES----EADQLLGNTMKDIITQEMTTAVQEPDATLSMV 477
            E   L    TT S+S      Y S    +A      T    +++E +T+  +P +T +  
Sbjct: 4063 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 4122

Query: 478  TQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTIS------TTVVPL 531
              +   T  L ++   T    +  +  +  PG T  S   +   T  S      TT++P 
Sbjct: 4123 FPDSTTTSGLSQEP-TTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP- 4180

Query: 532  SFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTP-PGIMVGEPSISPALPALEASSERRTVV 590
                  T+   +   + P    T  L + +TP      G    S    +  +SS+     
Sbjct: 4181 ----DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSP 4236

Query: 591  PSITRVNTAAS 601
            PS T V    S
Sbjct: 4237 PSTTAVPVEVS 4247



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 95/474 (20%), Positives = 163/474 (34%), Gaps = 60/474 (12%)

Query: 125  VFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETTKGFL 184
            + G S+  + S  S  A A   +   +TPS+ V +      S+           TTK  L
Sbjct: 573  ISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGL 632

Query: 185  KYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAG 244
                   ++  S       H P+S   T   ++    T      + H TT+FPG+ +  G
Sbjct: 633  SEKSTTFYS--SPRSPDTTHLPASM--TSSGVSEESTTSHSRPGSTH-TTAFPGSTTMPG 687

Query: 245  SEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAV 304
                           ++ ++T + ++  P +T   TLS    T S LG PE T   S   
Sbjct: 688  ---------------LSQESTASHSSPGPTDT---TLSPGSTTASSLG-PEYTTFHSR-- 726

Query: 305  PAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGG-QPWTEAA 363
            P ++  +   D+T    +     P           T +S     + +G       W  + 
Sbjct: 727  PGSTETTLLPDNTTASGLLEASMPVHSSTRSPH--TTLSPAGSTTRQGESTTFHSWPSSK 784

Query: 364  QVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQST----- 418
                  P   +        +HG+  S   T  S+ + TS + +   +  +   ST     
Sbjct: 785  DTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHF 844

Query: 419  --GDFTESTKENDALFFLETTVSVSVYESEADQLL----------GNTMKDIITQEMTTA 466
               D T    E        TT ++S   S    L+          G+T         TT+
Sbjct: 845  PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 904

Query: 467  VQEPDATLSMVTQEQVATLEL-IRDSGKTEEEKEDPSPVSD-------------VPGVTQ 512
             +  ++T S  +Q+   T+ L  R +      +   SP+S               PG+++
Sbjct: 905  GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 964

Query: 513  LSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
             S  +     + +TT+ P S   +   EE   + + P    T       T PG+
Sbjct: 965  RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 1018



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 117/558 (20%), Positives = 198/558 (35%), Gaps = 72/558 (12%)

Query: 41   HAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQ 100
            H+  G +  M+  +   +S  S+++ +   S     +S+ PS TS       +  + PG 
Sbjct: 1916 HSSPGSTQTMHFPESSTASGRSEES-RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG- 1973

Query: 101  AGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEK 160
                       ST T +  P +    G S+    S  S  A   + +   +T S+     
Sbjct: 1974 -----------STAT-THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV----- 2016

Query: 161  EELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNP 220
              LL  +   PI     ETT        + +    S++      SP S   T    +T  
Sbjct: 2017 --LLGESTTSPISSGSMETTA----LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 2070

Query: 221  KTEKFEADTDH------RTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPL 274
                 E+ T H       TT+FP + +T G    S T      S  T     +  T  P 
Sbjct: 2071 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2130

Query: 275  ETSEYTLSVEPETDSLLGAPEVTVSVS--------TAVPAASALSDEWDDTKLESVSRIR 326
            + S  + S    TD+ L +P  T ++S         + P ++  +   D T    +    
Sbjct: 2131 QESTTSHSSPGSTDTAL-SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2189

Query: 327  TPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGN 386
            T     +     RT +S  +  S  G++G     +    +         T TA +     
Sbjct: 2190 TRV--HSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT 2246

Query: 387  -ERSPAFTDQSSF--TPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS-VSV 442
              RSP  T  + F  + T+     K +I +        T S+  +      E+T S +S 
Sbjct: 2247 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2306

Query: 443  YESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPS 502
              +E   L G+T    +++  TT    P +  + ++   + +L +  +S  +  +     
Sbjct: 2307 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ----- 2361

Query: 503  PVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVT 562
                 PG T              +TV P S   TP + E+  TV   +   T     P T
Sbjct: 2362 -----PGSTH-------------STVSPAS-TTTPGLSEESTTVYSSSPGSTETTVFPRT 2402

Query: 563  PPGIMVG-EPSISPALPA 579
            P   + G EP+   + PA
Sbjct: 2403 PTTSVRGEEPTTFHSRPA 2420



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 106/443 (23%), Positives = 152/443 (34%), Gaps = 82/443 (18%)

Query: 203  GHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPGS-----LTPDKEKP 257
            GHS  S +       ++P        + H TTS  G  +T+   PGS     L      P
Sbjct: 2741 GHSEKSTI-----FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2795

Query: 258  SQMTADNTQAAATKQPLET----SEYTLSVEPETDSLLGAPEVTVS-VSTAVPAASALSD 312
                A  T  ++ + P  T    S  +L V  E+ +    P  T S VS A      LS+
Sbjct: 2796 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 2855

Query: 313  EWDDTKLESVSRIRTPKLGDNEETQVRTE----------MSQTAQVSHEGMEGGQPWTEA 362
            E       S     T     +  T VR E           + T   + +    G   TE 
Sbjct: 2856 ESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEE 2913

Query: 363  AQVALGLPEGETHTG--TALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGD 420
            +    G P   T TG    L  A   E S  F   S  T T+L             ++G 
Sbjct: 2914 STAFPGSP-ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST-------TSGL 2965

Query: 421  FTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMT---TAVQEPDATLSMV 477
              EST              +S   +E   L G+     ++++ T   T+ + PDATLS  
Sbjct: 2966 VGESTPSR-----------LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 3014

Query: 478  TQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVT- 536
            T            SG +EE     S     PG T  +      A   STT   LS E T 
Sbjct: 3015 T---------TTSSGVSEESSTSHSQ----PGSTHTT------AFPDSTTTSGLSQEPTA 3055

Query: 537  ---------PTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERR 587
                      T+     T +   ++ T    SP      ++ + +I+  L  +EAS+   
Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL--VEASTPTH 3113

Query: 588  TVVPSITRVNTAASYGLDQLESE 610
            +   S+    T AS     L+ E
Sbjct: 3114 SSTGSLHTTLTPASSTSAGLQEE 3136



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 116/563 (20%), Positives = 197/563 (34%), Gaps = 54/563 (9%)

Query: 41   HAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQ 100
            H+  G +  M+  + + +S   +++     S    + SA PS TS       +  + PG 
Sbjct: 833  HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSYHSSPG- 890

Query: 101  AGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEK 160
                       ST T +  P +    G S+    S  S  A   + +   +T S+     
Sbjct: 891  -----------STAT-THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV----- 933

Query: 161  EELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNP 220
              LL  +   PI     ETT        + +    S+       SP S   T    +T  
Sbjct: 934  --LLGESTTSPISSGSMETTA----LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 987

Query: 221  KTEKFEADTDH------RTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPL 274
                 E+ T         TT+FP + +T G    S T      S  T     +  T  P 
Sbjct: 988  SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 1047

Query: 275  ETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEW--------DDTKLESVSRIR 326
            + S  + S    TD+ L +P  T ++S    + +  S+          D T    +    
Sbjct: 1048 QESTTSHSSSGSTDTAL-SPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 1106

Query: 327  TPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGN 386
            T     +     RT +S  +  S  G++G     +    +         T TA +     
Sbjct: 1107 TRV--HSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT 1163

Query: 387  -ERSPAFTDQSSF--TPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS-VSV 442
              RSP  T  + F  + T+     K +I +        T S+  +      E+T S +S 
Sbjct: 1164 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 1223

Query: 443  YESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEE----K 498
              +E   L G+T    +++  TT    P +  + ++   + +L +  +S  +  +     
Sbjct: 1224 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 1283

Query: 499  EDPSPVS-DVPGVTQLSRR-WEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPV 556
               SP S   PG+++ S   +     +  TTV P S   +   EE     + P    T +
Sbjct: 1284 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 1343

Query: 557  LGSPVTPPGIMVGEPSISPALPA 579
                 T  G +  E +  P  PA
Sbjct: 1344 FTEDSTTSG-LTEESTAFPGSPA 1365



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 97/502 (19%), Positives = 159/502 (31%), Gaps = 59/502 (11%)

Query: 96   TQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERIS-PESGLAKAMLTIAITATPS 154
            T PG +    T      +PT +  P++    G  +    S  + G   + ++ A T TP 
Sbjct: 2319 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2378

Query: 155  LTVDEKEELLTSTNFQPIVEEIT--------------ETTKGFLKYMDNQSFATESQEGV 200
            L+    EE  T  +  P   E T               TT        + +  TE     
Sbjct: 2379 LS----EESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2434

Query: 201  GLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPG-----------AESTAGSEPGS 249
            GL    +++  +     T        AD    +T+FP            A ST     G 
Sbjct: 2435 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2494

Query: 250  LTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASA 309
             TP +  PS         + T   L     T    P +     +P  T S   +  ++++
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 2554

Query: 310  LSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEA--AQVAL 367
             S               TP L  +  T   +  S    +         P  E+  +  + 
Sbjct: 2555 HSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP 2614

Query: 368  GLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKE 427
            G  +     G+   ++ G E S  F      T T+L  D          S+G    ST+ 
Sbjct: 2615 GSTDTALSPGSTTALSFGQE-STTFHSSPGSTHTTLFPDSTT-------SSGIVEASTRV 2666

Query: 428  NDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLEL 487
            + +     TT+S +   S +  L G         E TT    P +T +  +    AT  +
Sbjct: 2667 HSSTGSPRTTLSPA--SSTSPGLQG---------ESTTFQTHPASTHTTPSPPSTATAPV 2715

Query: 488  IRDSGKTEEEKEDPSPVSDVP------GVTQLSRRWEPLATTISTTVVPLSFEVTPTVEE 541
              +   T       +P +  P      G ++ S  +        TT        +   E 
Sbjct: 2716 --EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2773

Query: 542  QMDTVTGPNEEFTPVLGSPVTP 563
                ++  + E T + GS  TP
Sbjct: 2774 TTSRISPGSTEITTLPGSTTTP 2795



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 87/394 (22%), Positives = 140/394 (35%), Gaps = 40/394 (10%)

Query: 192 FATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAE---------ST 242
           FA+   +G G     S  +   E        EK   +T    ++F G           S 
Sbjct: 114 FASPGDDGDGRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSI 173

Query: 243 AGSEPGSLTPDKEKPSQMTADN-------TQAAATKQPLETSEYTLSVEPETDSLLGAPE 295
            G+   + TP    P    +D        T + ATK  L++S  +   E  T S  G   
Sbjct: 174 GGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGA 233

Query: 296 VTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEG 355
              ++  +  A S    E   + + S S + T  L  +  T   +E S T   S    + 
Sbjct: 234 TGTTLFPSHSATSVFVGEPKTSPITSAS-METTALPGSTTTAGLSEKSTTFYSSPRSPD- 291

Query: 356 GQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLL 415
            +  + A   + G+ E  T + +      G   + AF D ++    S       SI    
Sbjct: 292 -RTLSPARTTSSGVSEKSTTSHSR----PGPTHTIAFPDSTTMPGVSQESTASHSIPGST 346

Query: 416 QSTGDFTESTKENDALFFLETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLS 475
            +T   +  T    +L    TT   S   ++  +L  NT    + +  T       +  +
Sbjct: 347 DTT--LSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHT 404

Query: 476 MVTQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEV 535
            ++     T E     G+    +  PS     P  +  +  +  L+TT  ++  P S   
Sbjct: 405 TLSPSSSTTHE-----GEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS--PSS--- 454

Query: 536 TPTVEEQMDTVT-GPNEEFTPVLGSPV----TPP 564
           TPT      + T G +EE TPV  SPV    TPP
Sbjct: 455 TPTTHFSASSTTLGHSEESTPVHSSPVATATTPP 488


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 111/466 (23%), Positives = 166/466 (35%), Gaps = 27/466 (5%)

Query: 115  TESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVE 174
            T SG+      F  S     S ++GL  A LT A     S T        T T   P   
Sbjct: 836  TTSGLTEESTAFPGSPA---STQTGLP-ATLTTADLGEESTTFPSSSGS-TGTKLSPA-- 888

Query: 175  EITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTT 234
                TT G +        +  S E   L  SP++   +++  T        +A     TT
Sbjct: 889  --RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 946

Query: 235  SFPGAE---STAGSEPGSLTPDKEKPSQMTADNTQAAATKQPLETS-EYTLSVEPETDSL 290
            +  G     ST+ S+PGS        S  T+D +Q   T    + S E TLS    T S 
Sbjct: 947  TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1006

Query: 291  LGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSH 350
            LG    T   S      + L D+   + L   S       G    T   T  S T+    
Sbjct: 1007 LGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--TPASSTSAGLQ 1064

Query: 351  EGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVS 410
            E     Q W  ++      P G T     +   + +  S   T   S + T+L    + +
Sbjct: 1065 EESTTFQSWPSSSDTTPS-PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 1123

Query: 411  IVNLLQ-STGDFTESTKENDALFFLETTVS-VSVYESEADQLLGNTMKDIITQEMTT--- 465
             V+    +TG     T+   ++   E T S +S   +E   L G+T    ++++ TT   
Sbjct: 1124 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 1183

Query: 466  AVQEPDATLSMVTQEQVATLELIRDS----GKTEEEKEDPSPVSDVPGVTQLSRRWEPLA 521
            + + PD TLS  +       E    S    G T       S  + +PGV+Q S       
Sbjct: 1184 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS--TTMPGVSQESTASHSSP 1241

Query: 522  TTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIM 567
             +  TT+ P S   +    E     + P    T +L    T  G++
Sbjct: 1242 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLL 1287



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 118/529 (22%), Positives = 184/529 (34%), Gaps = 80/529 (15%)

Query: 96   TQPGQAGLMQTERPGVSTPTESGVPSAEEVFGSSQPERIS-PESGLAKAMLTIAITATPS 154
            T PG +    T      +PT +  P++    G  +    S  + G   + ++ A T TP 
Sbjct: 723  TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 782

Query: 155  L-----TVDEKEELLTSTNFQP-----IVEEITETTKGFLKYMDNQSFATESQEGVGLGH 204
            L     TV       T T   P      V     TT        + +  TE     GL  
Sbjct: 783  LSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 842

Query: 205  SPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSE-----------PGSLTPD 253
              +++  +     T        AD    +T+FP +  + G++            G  TP 
Sbjct: 843  ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 902

Query: 254  KEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDE 313
            +  PS         + T   L     T    P       +P+ T+S +T    +S +S+E
Sbjct: 903  RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR------SPDATLSPATT--TSSGVSEE 954

Query: 314  WDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGE 373
               T         T    D+  T   +++SQ    SH      Q  TEA      L  G 
Sbjct: 955  -SSTSHSQPGSTHTTAFPDSTTT---SDLSQEPTTSH----SSQGSTEAT-----LSPGS 1001

Query: 374  THTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFF 433
            T T ++L      ++S  F      T T+L+ D  +       ++G    ST  + +   
Sbjct: 1002 T-TASSL-----GQQSTTFHSSPGDTETTLLPDDTI-------TSGLVEASTPTHSSTGS 1048

Query: 434  LETTVSVSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRD--- 490
            L TT++ +   S   Q    T +   +   TT    P  T + V   +V+T    R    
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP-SPPGTTAAPV---EVSTTYHSRPSST 1104

Query: 491  -------SGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTI---STTVVPLSFEVTPTVE 540
                   S  T    E+ + V   PG T  +      AT++     T  P+S   T T  
Sbjct: 1105 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 1164

Query: 541  EQMDTVT-GPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRT 588
                T T G +E+ T    SP +P      + ++SPA       SE  T
Sbjct: 1165 LPGSTTTAGLSEKSTTFYSSPRSP------DTTLSPASTTSSGVSEEST 1207



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 95/474 (20%), Positives = 163/474 (34%), Gaps = 60/474 (12%)

Query: 125 VFGSSQPERISPESGLAKAMLTIAITATPSLTVDEKEELLTSTNFQPIVEEITETTKGFL 184
           + G S+  + S  S  A A   +   +TPS+ V +      S+           TTK  L
Sbjct: 60  ISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGL 119

Query: 185 KYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAG 244
                  ++  S       H P+S   T   ++    T      + H TT+FPG+ +  G
Sbjct: 120 SEKSTTFYS--SPRSPDTTHLPASM--TSSGVSEESTTSHSRPGSTH-TTAFPGSTTMPG 174

Query: 245 SEPGSLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVEPETDSLLGAPEVTVSVSTAV 304
                          ++ ++T + ++  P +T   TLS    T S LG PE T   S   
Sbjct: 175 ---------------LSQESTASHSSPGPTDT---TLSPGSTTASSLG-PEYTTFHSR-- 213

Query: 305 PAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQTAQVSHEGMEGG-QPWTEAA 363
           P ++  +   D+T    +     P           T +S     + +G       W  + 
Sbjct: 214 PGSTETTLLPDNTTASGLLEASMPVHSSTRSPH--TTLSPAGSTTRQGESTTFHSWPSSK 271

Query: 364 QVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQST----- 418
                 P   +        +HG+  S   T  S+ + TS + +   +  +   ST     
Sbjct: 272 DTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHF 331

Query: 419 --GDFTESTKENDALFFLETTVSVSVYESEADQLL----------GNTMKDIITQEMTTA 466
              D T    E        TT ++S   S    L+          G+T         TT+
Sbjct: 332 PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 391

Query: 467 VQEPDATLSMVTQEQVATLEL-IRDSGKTEEEKEDPSPVSD-------------VPGVTQ 512
            +  ++T S  +Q+   T+ L  R +      +   SP+S               PG+++
Sbjct: 392 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 451

Query: 513 LSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGI 566
            S  +     + +TT+ P S   +   EE   + + P    T       T PG+
Sbjct: 452 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 505



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 116/563 (20%), Positives = 197/563 (34%), Gaps = 54/563 (9%)

Query: 41  HAEKGQSDKMNTDDLENSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQPGQ 100
           H+  G +  M+  + + +S   +++     S    + SA PS TS       +  + PG 
Sbjct: 320 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSYHSSPG- 377

Query: 101 AGLMQTERPGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAITATPSLTVDEK 160
                      ST T +  P +    G S+    S  S  A   + +   +T S+     
Sbjct: 378 -----------STAT-THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV----- 420

Query: 161 EELLTSTNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNP 220
             LL  +   PI     ETT        + +    S+       SP S   T    +T  
Sbjct: 421 --LLGESTTSPISSGSMETTA----LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 474

Query: 221 KTEKFEADTDH------RTTSFPGAESTAGSEPGSLTPDKEKPSQMTADNTQAAATKQPL 274
                E+ T         TT+FP + +T G    S T      S  T     +  T  P 
Sbjct: 475 SGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 534

Query: 275 ETSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEW--------DDTKLESVSRIR 326
           + S  + S    TD+ L +P  T ++S    + +  S+          D T    +    
Sbjct: 535 QESTTSHSSSGSTDTAL-SPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 593

Query: 327 TPKLGDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGN 386
           T     +     RT +S  +  S  G++G     +    +         T TA +     
Sbjct: 594 TRV--HSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT 650

Query: 387 -ERSPAFTDQSSF--TPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS-VSV 442
             RSP  T  + F  + T+     K +I +        T S+  +      E+T S +S 
Sbjct: 651 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 710

Query: 443 YESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEE----K 498
             +E   L G+T    +++  TT    P +  + ++   + +L +  +S  +  +     
Sbjct: 711 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 770

Query: 499 EDPSPVS-DVPGVTQLSRR-WEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPV 556
              SP S   PG+++ S   +     +  TTV P S   +   EE     + P    T +
Sbjct: 771 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 830

Query: 557 LGSPVTPPGIMVGEPSISPALPA 579
                T  G +  E +  P  PA
Sbjct: 831 FTEDSTTSG-LTEESTAFPGSPA 852


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 25/208 (12%)

Query: 479 QEQVATLELIRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVVPLSFEVTPT 538
           +E+ + +E+  +S   +     P  +  +P          P+A T   T  P      P 
Sbjct: 770 KEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASP----PVPA 825

Query: 539 VEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISP-------ALPALEASSERRTVVP 591
            EE  +    P     P    P  P  + +  P + P         PALE          
Sbjct: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED-------- 877

Query: 592 SITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEED--KDADSLDEGLDG 649
            +T +N  +S   D+ E EE +E+E+EE+EE+E+E+ E+EEEDEE+  ++ +  +E  + 
Sbjct: 878 -LTVININSS---DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933

Query: 650 DTELPGFTLPGITSQEPGLEEGNMDLLE 677
           + E     L     +E   EE  ++ +E
Sbjct: 934 EFEEEEGELEEEEEEEDEEEEEELEEVE 961



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 1/51 (1%)

Query: 605 DQLESEEGQ-EDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELP 654
           ++ E EEG+ E+E+EE++E+E+EE E+ E+ E       ++EG      LP
Sbjct: 933 EEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP 983


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 6/114 (5%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQEPG 667
           E EE +E+++EE+EEDE+EEEE+EEE+EE+++ +  +E       L     P   S   G
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEG 792

Query: 668 LEEGNMDLLEGATYQVPDALEWEQQNQGLVRSWME--KLKDKAGYMSGMLVPVG 719
            E       EGA    P  L  + Q +   R+ M    L+ + G  + +LV  G
Sbjct: 793 SERSTDRSQEGA----PSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPG 842



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 13/105 (12%)

Query: 561 VTPPGIMVGEPSISP-ALPA------LEASSERRTVVPSITRVN------TAASYGLDQL 607
           V PP  + G P   P +LP       L    ER  ++  + RV       T     L  +
Sbjct: 666 VAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPV 725

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           + +   ++E+EE+EEDE+EEEEDEEE+EE+++ +  +E  + + E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/185 (23%), Positives = 77/185 (41%), Gaps = 21/185 (11%)

Query: 488 IRDSGKTEEEKEDPSPVSDVPGVTQLSRRWEPLATTISTTVV--PLSFEVTPTVEEQMDT 545
           + +  + EE  ED    S    V    ++ +  A T +  VV  P       T  ++   
Sbjct: 24  VEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAV 83

Query: 546 VTGPNEEFTPVLGSPVTPPGIMV--GEPSISPALPALEASSERRTVVPSITRVNTAASYG 603
             G     TP   + VTP   +   G+   +P    +    ++   +P+    N   +  
Sbjct: 84  TPGKKAAATPAKKT-VTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKK 142

Query: 604 LDQLESEEGQEDEDEEDEEDEDEEEED----------------EEEDEEDKDADSLDEGL 647
            D  E E+   +EDEED+EDEDE+E++                +E+DE+D+D +  D+  
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202

Query: 648 DGDTE 652
           + D+E
Sbjct: 203 EDDSE 207



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 22/76 (28%), Positives = 46/76 (60%), Gaps = 4/76 (5%)

Query: 570 EPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEE 629
           + S   A+    A  ++   V  +   N A     D+ E E+ ++++D++DE+DED+++E
Sbjct: 204 DDSEEEAMETTPAKGKKAAKVVPVKAKNVAE----DEDEEEDDEDEDDDDDEDDEDDDDE 259

Query: 630 DEEEDEEDKDADSLDE 645
           D+EE+EE+++ + + E
Sbjct: 260 DDEEEEEEEEEEPVKE 275



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 19/50 (38%), Positives = 34/50 (68%)

Query: 616 EDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQE 665
           EDE++EED+++E++D++ED+ED D +  +E  + + E P    PG   +E
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 15/45 (33%), Positives = 34/45 (75%)

Query: 611 EGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
           E +++E+++++ED+D++E+DE++D+ED + +  +E  +   E PG
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPG 278



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 26/90 (28%)

Query: 589 VVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEE-------------------- 628
           + P+  +   AA    D+ + ++  +++D++DEED+ EEE                    
Sbjct: 170 IEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKA 229

Query: 629 ------EDEEEDEEDKDADSLDEGLDGDTE 652
                 EDEEED+ED+D D  ++  D D E
Sbjct: 230 KNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259



 Score = 37.0 bits (84), Expect = 0.070
 Identities = 14/34 (41%), Positives = 25/34 (73%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDK 638
           D  + E+ ++D+DE+DEE+E+EEEE+  ++   K
Sbjct: 246 DDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGK 279



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 12/35 (34%), Positives = 22/35 (62%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD 639
           D  + E+  +++DEE+EE+E+EE   E   +  K+
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 22/45 (48%), Positives = 36/45 (80%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           E EE +E+E+EEDEE+E+EEEE+EEE+EE+++ +  +E  + + E
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 21/41 (51%), Positives = 35/41 (85%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
           ++ E EE +E+EDEE+EE+E+EEEE+EEE+EE+++ +  +E
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 21/41 (51%), Positives = 35/41 (85%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
           ++ E EE +EDE+EE+EE+E+EEEE+EEE+EE+++ +  +E
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 22/49 (44%), Positives = 37/49 (75%)

Query: 604 LDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           L   E +E +E+E+EE+EEDE+EEEE+EEE+EE+++ +  +E  + + E
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 23/63 (36%), Positives = 42/63 (66%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGIT 662
           G+   E E+ +E+E+EE+EE+++EEEE+EEE+EE+++ +  +E  + + E      P + 
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312

Query: 663 SQE 665
            QE
Sbjct: 313 FQE 315



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 21/47 (44%), Positives = 36/47 (76%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           ++ + EE +E+E+EE+EE+E+EEEE+EEE+EE+++  + D     DT
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 17/48 (35%), Positives = 34/48 (70%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           ++   ++G    +EEDEE+E+EEEE+EE++EE+++ +  +E  + + E
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 18/49 (36%), Positives = 30/49 (61%)

Query: 604 LDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           L+   SEE  + +     E+EDEEEE+EEE+EE+ + +  +E  + + E
Sbjct: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 288



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 593 ITRVNTAASYGLDQLESEEGQEDEDEED------EEDEDEEEEDEEEDEEDKDADSLDEG 646
           +  V T  S  L     E+   +E  +       EE+++EEEE+EEE+EED++ +  +E 
Sbjct: 224 VVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEE 283

Query: 647 LDGDTE 652
            + + E
Sbjct: 284 EEEEEE 289



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 23/98 (23%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSL--------------------- 643
           ++ E EE +E+E+EE+EE+E   +   +ED     A                        
Sbjct: 287 EEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEV 346

Query: 644 --DEGLDGDTELPGFTLPGITSQEPGLEEGNMDLLEGA 679
             D+  D DT     T+   +  +  +  GN+ LLE A
Sbjct: 347 RSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQA 384


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 22/38 (57%), Positives = 33/38 (86%)

Query: 604  LDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDAD 641
            L +  SEE +E+EDEE+EE+E+EEEEDEEE+EE+++ +
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 22/54 (40%), Positives = 38/54 (70%)

Query: 606  QLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLP 659
            +L  E  +E+E+EEDEE+E+EEEE+EE++EE+++ +  +E  +  +  P  T P
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 24/57 (42%), Positives = 39/57 (68%)

Query: 583  SSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD 639
            S E R V     ++   +    ++ E EE +E+E+EE+EE+EDEEEE+EEE+EE+++
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 23/124 (18%)

Query: 530  PLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEPSISPALPALEASSERRTV 589
            P+  +   TVEEQ +T  G             T P  +  E  +     AL    E R  
Sbjct: 1280 PMEPDEQVTVEEQKETSEGK------------TSPSPIRIEEEVKETGEALLPQEENR-- 1325

Query: 590  VPSITRVNTAASYGLDQLESEEGQED----EDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
                 R  T A    +    E+ ++D    E+EE+EE+E+EEEE+EEE EE++   ++++
Sbjct: 1326 -----REETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK 1380

Query: 646  GLDG 649
              DG
Sbjct: 1381 DPDG 1384



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/40 (45%), Positives = 30/40 (75%)

Query: 606  QLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
            QL     +  E+EE+EEDE+EEEE+EEE+E++++ +  +E
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 16/39 (41%), Positives = 31/39 (79%)

Query: 607  LESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
            LE  +   +E+EE+E++E+EEEE+EEE++E+++ +  +E
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEE 1100



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 20/55 (36%), Positives = 35/55 (63%)

Query: 611  EGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQE 665
            E  ++  EE+EE+EDEEEE+EEE+EE+ + +  +E  + + E    + P +T  +
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 17/43 (39%), Positives = 29/43 (67%)

Query: 610  EEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
            E GQ  E  ++  +E+EEEEDEEE+EE+++ +  +E  + + E
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 120/572 (20%), Positives = 190/572 (33%), Gaps = 82/572 (14%)

Query: 52  TDDLENSSVTSKQTPQ---LVVSEDPMMMSAVPSATSLNKAFSINKETQPGQAGLMQTER 108
           T  +  +  TS  TP    L+   +    S     TS+    + +  T      +  TE 
Sbjct: 49  TSSISTTETTSHSTPSFTSLITITETTSHSTPSYTTSITTTETPSHSTPSYTTSITTTET 108

Query: 109 PGVSTPTESGVPSAEEVFGSSQPERISPESGLAKAMLTIAIT--ATPSLTVDEKEELLTS 166
           P  STP+ +   +  E    S P           ++ T   T  +TPS T       +T 
Sbjct: 109 PSHSTPSFTSSITTTETTSHSTP-------SFTSSIRTTETTSYSTPSFT---SSNTITE 158

Query: 167 TNFQPIVEEITETTKGFLKYMDNQSFATESQEGVGLGHSPSSYVNTKEMLTTNPKTEKFE 226
           T        IT  T          SF++         HS   + ++   +TT   TE   
Sbjct: 159 TTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSHSTPGFTSS---ITT---TETTS 212

Query: 227 ADTDHRTTSFPGAESTAGSEPG--SLTPDKEKPSQMTADNTQAAATKQPLETSEYTLSVE 284
             T   T+S    E+T+   P   S     E PS  T  +T        + T++ T    
Sbjct: 213 HSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSSTSL------ITTTKTTSHST 266

Query: 285 PETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLESVSRIRTPKLGDNEETQVRTEMSQ 344
           P   S +   E T   + +  ++   ++          S I T +   +  T   + ++ 
Sbjct: 267 PSFTSSITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITT 326

Query: 345 TAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTALLIAHGNERSPAFTDQSSFTPTSLM 404
           T   SH         T +   ++        T T          S      +  TP+SL 
Sbjct: 327 TETTSHS--------TPSFSSSI--------TTTETXXXXXXXTSETAVTPTPVTPSSLS 370

Query: 405 EDMKVSIVNLL--QSTGDFTESTKEND------ALFFLET-----TVSVSVYESEADQLL 451
            D+  + +  L   S G  T  T   D       +  L T     + S S+  +E   L+
Sbjct: 371 TDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLV 430

Query: 452 GNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKEDPSPVSDVPGVT 511
           G T   + T  MT  + E     S  T   V            E   + P  ++   G T
Sbjct: 431 GTTSPTMSTVRMTLRITENTPISSFSTSIVVI----------PETPTQTPPVLTSATG-T 479

Query: 512 QLSRRWEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEEFTPVLGSPVTPPGIMVGEP 571
           Q S    P  TT+       +F  T +    + T+T      T V  S V  P       
Sbjct: 480 QTS----PAPTTV-------TFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTL 528

Query: 572 SISPALPALEAS--SERRTVVPSITRVNTAAS 601
             +P+ P+L+ S  S       S TR +T+ +
Sbjct: 529 QTTPSTPSLQTSLTSTSEFTTESFTRGSTSTN 560



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 85/406 (20%), Positives = 134/406 (33%), Gaps = 44/406 (10%)

Query: 205 SPSSYVNTKEMLTTNPKTEKFEADTDHRTTSFPGAESTAGSEPG--SLTPDKEKPSQMTA 262
           +PSS  +T    ++   TE     T   T+S    E+T+ S P   SL    E  S  T 
Sbjct: 23  TPSS--STPSFTSSITTTETTSHSTPSFTSSISTTETTSHSTPSFTSLITITETTSHSTP 80

Query: 263 DNTQAAATKQPLE--TSEYTLSVEPETDSLLGAPEVTVSVSTAVPAASALSDEWDDTKLE 320
             T +  T +     T  YT S+          P  T S++T    + +        +  
Sbjct: 81  SYTTSITTTETPSHSTPSYTTSITTTETPSHSTPSFTSSITTTETTSHSTPSFTSSIRTT 140

Query: 321 SVSRIRTPKL-GDNEETQVRTEMSQTAQVSHEGMEGGQPWTEAAQVALGLPEGETHTGTA 379
             +   TP     N  T+  +  + +   S    E     T +   ++   E  +H+   
Sbjct: 141 ETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETTSHS--- 197

Query: 380 LLIAHGNERSPAFTDQSSFTPTSLMEDMKVSIVNLLQSTGDFTESTKENDALFFLETTVS 439
                    +P FT   + T T+              ST  FT S    +       + +
Sbjct: 198 ---------TPGFTSSITTTETTS------------HSTPSFTSSITTTETTSHDTPSFT 236

Query: 440 VSVYESEADQLLGNTMKDIITQEMTTAVQEPDATLSMVTQEQVATLELIRDSGKTEEEKE 499
            S+  SE       +   +IT   TT+   P  T S+ T E  +       S  T  E  
Sbjct: 237 SSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETT 296

Query: 500 DPSPVSDVPGVTQLSRR-------WEPLATTISTTVVPLSFEVTPTVEEQMDTVTGPNEE 552
             +  S    +T               + TT +T+    SF  + T  E          E
Sbjct: 297 SHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSE 356

Query: 553 FTPVLGSPVTPPGIMVGEP-----SISPALPALEASSERRTVVPSI 593
            T V  +PVTP  +    P     +++P+      S    T  PSI
Sbjct: 357 -TAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSI 401


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 22/120 (18%)

Query: 608  ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQEPG 667
            E EE +++E+E +EEDE+E+EEDEEE  ++K+ +  +E    + E           +E G
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGE-----------KEEG 1921

Query: 668  LEEG--NMDLLEGATYQVPDALEW--EQQNQGLVRS-------WMEKLKDKAGYMSGMLV 716
            LEEG   M L E    Q+   LE+  +Q+ Q  V S       +++KL+       G+L+
Sbjct: 1922 LEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLI 1981


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 22/120 (18%)

Query: 608  ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQEPG 667
            E EE +++E+E +EEDE+E+EEDEEE  ++K+ +  +E    + E           +E G
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGE-----------KEEG 1921

Query: 668  LEEG--NMDLLEGATYQVPDALEW--EQQNQGLVRS-------WMEKLKDKAGYMSGMLV 716
            LEEG   M L E    Q+   LE+  +Q+ Q  V S       +++KL+       G+L+
Sbjct: 1922 LEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYGLLI 1981


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/76 (38%), Positives = 43/76 (56%), Gaps = 6/76 (7%)

Query: 581 EASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD- 639
           E  S +R  +  +   N  +S    Q +SE  ++DE++ED+EDEDEEEED+E  +  +D 
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669

Query: 640 -----ADSLDEGLDGD 650
                + S DE  DGD
Sbjct: 670 GDSSESSSEDESEDGD 685



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 19/44 (43%), Positives = 32/44 (72%), Gaps = 2/44 (4%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           ESE+G  DE+EED+EDED++E+D+E+++ + +  S      GD+
Sbjct: 680 ESEDG--DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 18/40 (45%), Positives = 29/40 (72%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADS 642
           G D  ES    E ED ++ E++DE+E+D+E+D+ED+D +S
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 15/47 (31%), Positives = 32/47 (68%)

Query: 609 SEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
           SE   EDE E+ +E+E+++E++++++++D+D D+  EG    +   G
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 13/44 (29%), Positives = 29/44 (65%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           + +E +ED+++ED++++D+E+ED E +     + S  +  D D+
Sbjct: 683 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/76 (38%), Positives = 43/76 (56%), Gaps = 6/76 (7%)

Query: 581 EASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD- 639
           E  S +R  +  +   N  +S    Q +SE  ++DE++ED+EDEDEEEED+E  +  +D 
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669

Query: 640 -----ADSLDEGLDGD 650
                + S DE  DGD
Sbjct: 670 GDSSESSSEDESEDGD 685



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 19/44 (43%), Positives = 32/44 (72%), Gaps = 2/44 (4%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           ESE+G  DE+EED+EDED++E+D+E+++ + +  S      GD+
Sbjct: 680 ESEDG--DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 721



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 18/40 (45%), Positives = 29/40 (72%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADS 642
           G D  ES    E ED ++ E++DE+E+D+E+D+ED+D +S
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 15/47 (31%), Positives = 32/47 (68%)

Query: 609 SEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
           SE   EDE E+ +E+E+++E++++++++D+D D+  EG    +   G
Sbjct: 673 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 13/44 (29%), Positives = 29/44 (65%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           + +E +ED+++ED++++D+E+ED E +     + S  +  D D+
Sbjct: 683 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/76 (38%), Positives = 43/76 (56%), Gaps = 6/76 (7%)

Query: 581 EASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD- 639
           E  S +R  +  +   N  +S    Q +SE  ++DE++ED+EDEDEEEED+E  +  +D 
Sbjct: 647 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 706

Query: 640 -----ADSLDEGLDGD 650
                + S DE  DGD
Sbjct: 707 GDSSESSSEDESEDGD 722



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 19/44 (43%), Positives = 32/44 (72%), Gaps = 2/44 (4%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           ESE+G  DE+EED+EDED++E+D+E+++ + +  S      GD+
Sbjct: 717 ESEDG--DENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDS 758



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 18/40 (45%), Positives = 29/40 (72%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADS 642
           G D  ES    E ED ++ E++DE+E+D+E+D+ED+D +S
Sbjct: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 15/47 (31%), Positives = 32/47 (68%)

Query: 609 SEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
           SE   EDE E+ +E+E+++E++++++++D+D D+  EG    +   G
Sbjct: 710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 13/44 (29%), Positives = 29/44 (65%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDT 651
           + +E +ED+++ED++++D+E+ED E +     + S  +  D D+
Sbjct: 720 DGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 21/50 (42%), Positives = 35/50 (70%)

Query: 606  QLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
            +L  EE ++DEDE+D+ED+D+E++DE++D+ED   DS +   +   E  G
Sbjct: 1683 ELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAG 1732



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 23/54 (42%), Positives = 36/54 (66%)

Query: 599  AASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
            AA+ G    E EE + +  EE+ ED+++E++DE++D+ED D D  DE L  D+E
Sbjct: 1667 AAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSE 1720



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 16/42 (38%), Positives = 32/42 (76%)

Query: 604  LDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDE 645
            L + E+E+ ++++D+ED++DED++E+D++ED      +SL E
Sbjct: 1684 LPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPE 1725



 Score = 33.9 bits (76), Expect = 0.59
 Identities = 14/44 (31%), Positives = 28/44 (63%), Gaps = 2/44 (4%)

Query: 605  DQLESEEGQEDEDEEDEEDEDEEE--EDEEEDEEDKDADSLDEG 646
            D  + ++ ++D+DE+D+ED+D+E+   D EE   +  A++   G
Sbjct: 1691 DDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAG 1734



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 18/75 (24%), Positives = 31/75 (41%)

Query: 558  GSPVTPPGIMVGEPSISPALPALEASSERRTVVPSITRVNTAASYGLDQLESEEGQEDED 617
            G P  P     G    + A  A    S +      +      A    D+ + E+  +++D
Sbjct: 1647 GDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDD 1706

Query: 618  EEDEEDEDEEEEDEE 632
            +ED++DED   + EE
Sbjct: 1707 DEDDDDEDLRTDSEE 1721


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 29/58 (50%), Positives = 37/58 (63%), Gaps = 8/58 (13%)

Query: 603 GLDQLESEEGQEDEDE-----EDEEDEDEEEEDEEED---EEDKDADSLDEGLDGDTE 652
           GLD  E +E +E+ DE     EDEEDEDEEEE EEED   EE++D +  ++G   D E
Sbjct: 166 GLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEE 223



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 9/79 (11%)

Query: 604 LDQLESEEGQEDEDEEDEEDE--------DEEEEDEEEDEEDKDADSLDEGLDGDTELPG 655
           L QL   +G + +D+E  + +        D+EEEDE+E+E D+DA  +++  D D E  G
Sbjct: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG 198

Query: 656 FTLPGITSQEPGLEEGNMD 674
                ++ +E   EEG  D
Sbjct: 199 -EEEDVSGEEEEDEEGYND 216



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 14/71 (19%)

Query: 604 LDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITS 663
           ++ L+ EE  EDE+E DE+ +  E+E++E++EE+ +    +E + G+ E           
Sbjct: 164 VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE----EEDVSGEEE----------E 209

Query: 664 QEPGLEEGNMD 674
            E G  +G +D
Sbjct: 210 DEEGYNDGEVD 220



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 17/38 (44%), Positives = 26/38 (68%)

Query: 611 EGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLD 648
           E +EDEDEE+E +E++   +EEEDEE  +   +D+  D
Sbjct: 187 EDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEED 224



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 26/60 (43%), Positives = 33/60 (55%), Gaps = 15/60 (25%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEE-----EEDEEEDEED---------KDADSLDEGLDGD 650
           D+ E EEG+E ED   EE+EDEE     E D+EEDEE+         +  +  DEG D D
Sbjct: 191 DEDEEEEGEE-EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249



 Score = 33.9 bits (76), Expect = 0.59
 Identities = 19/48 (39%), Positives = 30/48 (62%), Gaps = 10/48 (20%)

Query: 602 YGLDQLESEEGQEDEDEEDEEDED---EEEEDEE-------EDEEDKD 639
           Y  D    E+ +++++EE+ E+ED   EEEEDEE       +DEED++
Sbjct: 179 YDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 32/68 (47%), Positives = 42/68 (61%), Gaps = 11/68 (16%)

Query: 608 ESEEGQEDEDEEDEEDED-EEEEDEEEDEEDKDADSLDEGLDGDTELPGFTLPGITSQEP 666
           E EE +E EDEEDE+DED EEEE +EED+ED+D     EG + D E+          +E 
Sbjct: 167 EEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV----EGDEDDDEV------SEEEEEF 216

Query: 667 GLEEGNMD 674
           GL+E + D
Sbjct: 217 GLDEEDED 224



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 27/60 (45%), Positives = 39/60 (65%), Gaps = 10/60 (16%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEE-----DKDADSLDE-----GLDGDTE 652
           G+D+ E +E  EDE++ED+ED +EEE DEE+DE+     D+D D + E     GLD + E
Sbjct: 164 GVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDE 223



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 22/47 (46%), Positives = 34/47 (72%), Gaps = 2/47 (4%)

Query: 608 ESEEGQEDEDEEDEEDEDEEEEDEEEDEEDK--DADSLDEGLDGDTE 652
           ++E    DE+EEDEE EDEE+ED+E+ EE++  + D  DE ++GD +
Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 24/50 (48%), Positives = 32/50 (64%), Gaps = 3/50 (6%)

Query: 603 GLDQLESEEGQEDEDEEDEEDEDEEEEDEEE---DEEDKDADSLDEGLDG 649
           G ++   EE  EDED E +ED+DE  E+EEE   DEED+D D  +E  +G
Sbjct: 185 GEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEG 234



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 25/59 (42%), Positives = 37/59 (62%), Gaps = 17/59 (28%)

Query: 608 ESEEGQEDE-DEEDEEDED------------EEEE---DEEEDEEDKDADSLDEGLDGD 650
           + E+G+E+E DEED+EDED            EEEE   DEE+++ED+D +  +EG  G+
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE-EEGGKGE 238



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 19/50 (38%), Positives = 32/50 (64%), Gaps = 2/50 (4%)

Query: 605 DQLESEEGQEDEDEEDEEDEDEEEEDEE--EDEEDKDADSLDEGLDGDTE 652
           D  + EE + DE+++++ED + +E+D+E  E+EE+   D  DE  D D E
Sbjct: 181 DDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 12/56 (21%)

Query: 605 DQLESEEGQEDEDE-----------EDEEDEDEEEEDEEEDE-EDKDADSLDEGLD 648
           D+ E  EG ED+DE           E++EDEDE+EE+EE  + E +  ++ DEG D
Sbjct: 195 DEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGED 250



 Score = 33.9 bits (76), Expect = 0.59
 Identities = 12/36 (33%), Positives = 25/36 (69%)

Query: 602 YGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEED 637
           +GLD+ + +E +++E+EE  + E  + E ++E E+D
Sbjct: 216 FGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 15/39 (38%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 608 ESEEGQEDEDE-EDEEDEDEEEEDEEEDEEDKDADSLDE 645
           E E G ++EDE EDE++E+EE    E+ + + D +  D+
Sbjct: 213 EEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 21/48 (43%), Positives = 38/48 (79%)

Query: 592 SITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKD 639
           ++ +V  + S   D+ E EEG+E+E+E +EE+E++EEE+EEE+EE+++
Sbjct: 349 NMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 22/70 (31%), Positives = 41/70 (58%)

Query: 581 EASSERRTVVPSITRVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDA 640
           E   + + V+         AS   D+ E EE + +E+EE+ E+E+EE+E+EEE+EE+++ 
Sbjct: 336 EGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE 395

Query: 641 DSLDEGLDGD 650
           +   +   G+
Sbjct: 396 EEPQQRGQGE 405


>gi|4504425 high-mobility group box 1 [Homo sapiens]
          Length = 215

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 24/45 (53%), Positives = 35/45 (77%), Gaps = 2/45 (4%)

Query: 599 AASYGLDQLES--EEGQEDEDEEDEEDEDEEEEDEEEDEEDKDAD 641
           AA  G+ + E   ++ +E+EDEEDEEDE+EEE++E+EDEE+ D D
Sbjct: 170 AAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDD 214



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 16/37 (43%), Positives = 27/37 (72%)

Query: 616 EDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTE 652
           E  + +++E+E+EEDEE++EE++D +  DE  D D E
Sbjct: 179 EKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE 215



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 13/38 (34%), Positives = 30/38 (78%)

Query: 611 EGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLD 648
           + ++ + +++EE+++E+EEDEEE+E+++D D  ++  D
Sbjct: 177 KAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDD 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.125    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,921,945
Number of Sequences: 37866
Number of extensions: 1598357
Number of successful extensions: 43257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 724
Number of HSP's successfully gapped in prelim test: 416
Number of HSP's that attempted gapping in prelim test: 15622
Number of HSP's gapped (non-prelim): 11565
length of query: 774
length of database: 18,247,518
effective HSP length: 110
effective length of query: 664
effective length of database: 14,082,258
effective search space: 9350619312
effective search space used: 9350619312
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.