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Search of human proteins with 55743149
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
(1298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 2681 0.0
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 2681 0.0
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 124 8e-28
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 124 8e-28
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 124 8e-28
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 124 8e-28
gi|19913367 transducin beta-like 1Y [Homo sapiens] 124 8e-28
gi|19913365 transducin beta-like 1Y [Homo sapiens] 124 8e-28
gi|15150805 transducin beta-like 1Y [Homo sapiens] 124 8e-28
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 120 6e-27
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 107 1e-22
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 107 1e-22
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 107 1e-22
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 100 1e-20
gi|32189425 WD repeat domain 69 [Homo sapiens] 96 2e-19
gi|157739942 gemin 5 [Homo sapiens] 95 4e-19
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 90 2e-17
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 90 2e-17
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 88 6e-17
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 88 6e-17
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 88 6e-17
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 87 8e-17
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 87 1e-16
gi|16554629 WD repeat domain 5 [Homo sapiens] 86 2e-16
gi|16554627 WD repeat domain 5 [Homo sapiens] 86 2e-16
gi|23199987 WD repeat domain 5B [Homo sapiens] 84 9e-16
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 82 3e-15
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 81 6e-15
gi|21071067 TBP-associated factor 5 [Homo sapiens] 80 2e-14
gi|118402582 cell division cycle 20 [Homo sapiens] 79 2e-14
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 2681 bits (6950), Expect = 0.0
Identities = 1298/1298 (100%), Positives = 1298/1298 (100%)
Query: 1 MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK 60
MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK
Sbjct: 1 MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK 60
Query: 61 TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF 120
TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF
Sbjct: 61 TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF 120
Query: 121 VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG 180
VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG
Sbjct: 121 VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG 180
Query: 181 NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL 240
NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL
Sbjct: 181 NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL 240
Query: 241 PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP 300
PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP
Sbjct: 241 PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP 300
Query: 301 PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW 360
PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW
Sbjct: 301 PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW 360
Query: 361 DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW 420
DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW
Sbjct: 361 DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW 420
Query: 421 APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF 480
APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF
Sbjct: 421 APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF 480
Query: 481 CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG 540
CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG
Sbjct: 481 CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG 540
Query: 541 HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL 600
HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL
Sbjct: 541 HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL 600
Query: 601 LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA
Sbjct: 601 LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
Query: 661 LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW 720
LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW
Sbjct: 661 LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW 720
Query: 721 FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS 780
FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS
Sbjct: 721 FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS 780
Query: 781 KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM 840
KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM
Sbjct: 781 KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM 840
Query: 841 QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV 900
QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV
Sbjct: 841 QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV 900
Query: 901 PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN 960
PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN
Sbjct: 901 PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN 960
Query: 961 ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL 1020
ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL
Sbjct: 961 ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL 1020
Query: 1021 MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL 1080
MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL
Sbjct: 1021 MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL 1080
Query: 1081 SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC 1140
SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC
Sbjct: 1081 SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC 1140
Query: 1141 GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL 1200
GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL
Sbjct: 1141 GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL 1200
Query: 1201 EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG 1260
EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG
Sbjct: 1201 EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG 1260
Query: 1261 PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF 1298
PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF
Sbjct: 1261 PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF 1298
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 2681 bits (6950), Expect = 0.0
Identities = 1298/1298 (100%), Positives = 1298/1298 (100%)
Query: 1 MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK 60
MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK
Sbjct: 25 MSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKK 84
Query: 61 TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF 120
TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF
Sbjct: 85 TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAF 144
Query: 121 VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG 180
VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG
Sbjct: 145 VSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPG 204
Query: 181 NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL 240
NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL
Sbjct: 205 NKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNL 264
Query: 241 PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP 300
PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP
Sbjct: 265 PSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSP 324
Query: 301 PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW 360
PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW
Sbjct: 325 PRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKW 384
Query: 361 DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW 420
DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW
Sbjct: 385 DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSW 444
Query: 421 APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF 480
APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF
Sbjct: 445 APGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGF 504
Query: 481 CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG 540
CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG
Sbjct: 505 CIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSG 564
Query: 541 HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL 600
HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL
Sbjct: 565 HTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL 624
Query: 601 LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA
Sbjct: 625 LISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 684
Query: 661 LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW 720
LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW
Sbjct: 685 LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRW 744
Query: 721 FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS 780
FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS
Sbjct: 745 FSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMS 804
Query: 781 KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM 840
KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM
Sbjct: 805 KFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLM 864
Query: 841 QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV 900
QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV
Sbjct: 865 QRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSV 924
Query: 901 PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN 960
PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN
Sbjct: 925 PKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGN 984
Query: 961 ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL 1020
ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL
Sbjct: 985 ELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLL 1044
Query: 1021 MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL 1080
MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL
Sbjct: 1045 MIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLL 1104
Query: 1081 SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC 1140
SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC
Sbjct: 1105 SQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILC 1164
Query: 1141 GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL 1200
GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL
Sbjct: 1165 GYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSL 1224
Query: 1201 EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG 1260
EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG
Sbjct: 1225 EDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQG 1284
Query: 1261 PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF 1298
PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF
Sbjct: 1285 PVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF 1322
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 124 bits (310), Expect = 8e-28
Identities = 104/376 (27%), Positives = 166/376 (44%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P+KN + E +N+A S+ HA +DG V ++ + K LR
Sbjct: 132 SHQNPSKNREATVNGE--------ENRAHSVN-NHAKPMEIDGEV---EIPSSKATVLR- 178
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 179 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 237 NKDVT-SLDWNTNG-TLLATGSYDGFARIWT-EDGNLASTLGQH-KGPIFALKWNRKGNY 292
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW QNN + T++ ++
Sbjct: 293 ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW-QNNTTFASCS---TDMCIHVCRL 348
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D+P+K F GHT +V +KW P +L S SDD T++IW Q+ CI+ L H +
Sbjct: 349 GCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 407
Query: 590 GLMWNTEIP--------YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W+ P +L S S+D T+++WD G C T+ H VY + P
Sbjct: 408 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK 467
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 468 Y-LASGSFDKCVHIWN 482
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +++ H + I+ K+ P P +LA+ASFD T+++WDI
Sbjct: 382 DMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 442 ERGVCTHTLTKHQEPVYSVAFSPDG-KYLASGSFDKCVHIWNTQSGNLVHSY--RGTGGI 498
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 499 FEVCWNARGDKVGASASDGSVCVL 522
Score = 34.7 bits (78), Expect = 0.61
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 55 MSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 114
+++H++ + ++++ P L ASGS D V IWN ++ T GI CWNA
Sbjct: 450 LTKHQEPVYSVAFSPDGKYL-ASGSFDKCVHIWNTQSGNLVHSYRGTGGI---FEVCWNA 505
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 124 bits (310), Expect = 8e-28
Identities = 104/376 (27%), Positives = 166/376 (44%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P+KN + E +N+A S+ HA +DG V ++ + K LR
Sbjct: 132 SHQNPSKNREATVNGE--------ENRAHSVN-NHAKPMEIDGEV---EIPSSKATVLR- 178
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 179 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 237 NKDVT-SLDWNTNG-TLLATGSYDGFARIWT-EDGNLASTLGQH-KGPIFALKWNRKGNY 292
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW QNN + T++ ++
Sbjct: 293 ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW-QNNTTFASCS---TDMCIHVCRL 348
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D+P+K F GHT +V +KW P +L S SDD T++IW Q+ CI+ L H +
Sbjct: 349 GCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 407
Query: 590 GLMWNTEIP--------YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W+ P +L S S+D T+++WD G C T+ H VY + P
Sbjct: 408 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK 467
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 468 Y-LASGSFDKCVHIWN 482
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +++ H + I+ K+ P P +LA+ASFD T+++WDI
Sbjct: 382 DMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 442 ERGVCTHTLTKHQEPVYSVAFSPDG-KYLASGSFDKCVHIWNTQSGNLVHSY--RGTGGI 498
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 499 FEVCWNARGDKVGASASDGSVCVL 522
Score = 34.7 bits (78), Expect = 0.61
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 55 MSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 114
+++H++ + ++++ P L ASGS D V IWN ++ T GI CWNA
Sbjct: 450 LTKHQEPVYSVAFSPDGKYL-ASGSFDKCVHIWNTQSGNLVHSYRGTGGI---FEVCWNA 505
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 124 bits (310), Expect = 8e-28
Identities = 104/376 (27%), Positives = 166/376 (44%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P+KN + E +N+A S+ HA +DG V ++ + K LR
Sbjct: 183 SHQNPSKNREATVNGE--------ENRAHSVN-NHAKPMEIDGEV---EIPSSKATVLR- 229
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 230 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 288 NKDVT-SLDWNTNG-TLLATGSYDGFARIWT-EDGNLASTLGQH-KGPIFALKWNRKGNY 343
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW QNN + T++ ++
Sbjct: 344 ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW-QNNTTFASCS---TDMCIHVCRL 399
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D+P+K F GHT +V +KW P +L S SDD T++IW Q+ CI+ L H +
Sbjct: 400 GCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 458
Query: 590 GLMWNTEIP--------YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W+ P +L S S+D T+++WD G C T+ H VY + P
Sbjct: 459 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK 518
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 519 Y-LASGSFDKCVHIWN 533
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +++ H + I+ K+ P P +LA+ASFD T+++WDI
Sbjct: 433 DMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 493 ERGVCTHTLTKHQEPVYSVAFSPDG-KYLASGSFDKCVHIWNTQSGNLVHSY--RGTGGI 549
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 550 FEVCWNARGDKVGASASDGSVCVL 573
Score = 34.7 bits (78), Expect = 0.61
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 55 MSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 114
+++H++ + ++++ P L ASGS D V IWN ++ T GI CWNA
Sbjct: 501 LTKHQEPVYSVAFSPDGKYL-ASGSFDKCVHIWNTQSGNLVHSYRGTGGI---FEVCWNA 556
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 124 bits (310), Expect = 8e-28
Identities = 104/376 (27%), Positives = 166/376 (44%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P+KN + E +N+A S+ HA +DG V ++ + K LR
Sbjct: 183 SHQNPSKNREATVNGE--------ENRAHSVN-NHAKPMEIDGEV---EIPSSKATVLR- 229
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 230 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 288 NKDVT-SLDWNTNG-TLLATGSYDGFARIWT-EDGNLASTLGQH-KGPIFALKWNRKGNY 343
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW QNN + T++ ++
Sbjct: 344 ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW-QNNTTFASCS---TDMCIHVCRL 399
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D+P+K F GHT +V +KW P +L S SDD T++IW Q+ CI+ L H +
Sbjct: 400 GCDRPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 458
Query: 590 GLMWNTEIP--------YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W+ P +L S S+D T+++WD G C T+ H VY + P
Sbjct: 459 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK 518
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 519 Y-LASGSFDKCVHIWN 533
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +++ H + I+ K+ P P +LA+ASFD T+++WDI
Sbjct: 433 DMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 493 ERGVCTHTLTKHQEPVYSVAFSPDG-KYLASGSFDKCVHIWNTQSGNLVHSY--RGTGGI 549
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 550 FEVCWNARGDKVGASASDGSVCVL 573
Score = 34.7 bits (78), Expect = 0.61
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 55 MSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNA 114
+++H++ + ++++ P L ASGS D V IWN ++ T GI CWNA
Sbjct: 501 LTKHQEPVYSVAFSPDGKYL-ASGSFDKCVHIWNTQSGNLVHSYRGTGGI---FEVCWNA 556
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 124 bits (310), Expect = 8e-28
Identities = 103/376 (27%), Positives = 162/376 (43%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P KN + E +N A + H+ +DG V ++ K LR
Sbjct: 130 SQQNPPKNREATVNGE--------ENGAHEIN-NHSKPMEIDGDV---EIPPNKATVLR- 176
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 177 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 235 NKDVT-SLDWNSDG-TLLAMGSYDGFARIWT-ENGNLASTLGQH-KGPIFALKWNKKGNY 290
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW N M C T++ ++
Sbjct: 291 VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN---MTFASCS-TDMCIHVCRL 346
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D P+K F GHT +V +KW P +L S SDD T++IW QDAC++ L H+ +
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 590 GLMW--------NTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W N +L S S+D T+++WD +G C T+ H VY + P
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGK 465
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 466 Y-LASGSFDKYVHIWN 480
Score = 90.9 bits (224), Expect = 7e-18
Identities = 69/266 (25%), Positives = 121/266 (45%), Gaps = 35/266 (13%)
Query: 381 DPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIW 440
D LLA S+DG ++W N A T ++G I++L W G ++ G + IW
Sbjct: 246 DGTLLAMGSYDGFARIWTENGNLAS-TLGQHKGPIFALKWNKKGNYVLSAGVDKT-TIIW 303
Query: 441 NVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----------IRTIDGKV 490
+ G+ Q+F H + + W +++ A+CS+D CI ++T G
Sbjct: 304 DAHTGEAKQQFPFHSAPALD-VDW--QNNMTFASCSTD-MCIHVCRLGCDHPVKTFQG-- 357
Query: 491 LHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKW 550
H V W + ++A+ +D ++++ + D + H+ +++ +KW
Sbjct: 358 -----HTNEVNAIKWDPSGM-LLASCSDDMTLKIW--SMKQDACVHDLQAHSKEIYTIKW 409
Query: 551 SPLREG--------ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLI 602
SP +L S S D TVR+WD Q C + L H PV + ++ + YL
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA- 468
Query: 603 SGSWDYTIKVWDTREGTCVDTVYDHG 628
SGS+D + +W+T+ G+ V + G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTG 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 68/271 (25%), Positives = 114/271 (42%), Gaps = 30/271 (11%)
Query: 410 GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQK---GKIIQRFNEH----------GT 456
G+E ++ +W P + +A G+ + A IWN+ + G Q H
Sbjct: 177 GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKY-KHPAAVFGCDWSQNNKDMIAT 515
+ + W+ D +A S DGF I T +G + +H +F W++ +++
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSA 294
Query: 516 GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQD 575
G + T + ++ T + + F H+A V W S S D + + D
Sbjct: 295 GVDKTTI-IWDAHTGEAK--QQFPFHSAPALDVDWQ--NNMTFASCSTDMCIHVCRLGCD 349
Query: 576 ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLT 635
+ GHT V + W+ LL S S D T+K+W ++ CV + H ++Y +
Sbjct: 350 HPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 636 CHPSRPFT--------MASCSRDSTVRLWSL 658
P+ P T +AS S DSTVRLW +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Score = 72.4 bits (176), Expect = 3e-12
Identities = 41/144 (28%), Positives = 70/144 (48%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +D H + I+ K+ P P +LA+ASFD T+++WD+
Sbjct: 380 DMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 440 EQGVCTHTLMKHQEPVYSVAFSPDG-KYLASGSFDKYVHIWNTQSGSLVHSY--QGTGGI 496
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 497 FEVCWNARGDKVGASASDGSVCVL 520
Score = 52.4 bits (124), Expect = 3e-06
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 93/398 (23%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE-------QKVIAKLDSTKG--I 104
++ H+ + +W P + DL ASGS D+ IWN+ E Q V+ G +
Sbjct: 174 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 105 PAS---LSWCWNAE-DVVAFVSHRGPLFIWTISGPDSGVI-VHKDAHSFLSDICMFRWHT 159
P++ S WN++ ++A S+ G IWT +G + + HK I +W
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHK------GPIFALKW-- 284
Query: 160 HQKGK-VVFGHIDGSLSIF--HPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLL 216
++KG V+ +D + I+ H G Q+ D ++ +T + STD +
Sbjct: 285 NKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT---FASCSTDMCI 341
Query: 217 VVNLHYGIRLVDSESLSC---ITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIW 273
V L C + TF V + W PS GM + S L+IW
Sbjct: 342 HVC-----------RLGCDHPVKTFQ--GHTNEVNAIKWDPS--GMLLASCSDDMTLKIW 386
Query: 274 NVSRTTPIDNLKLKKTGFHCLHVLNSPPRKKFSVQ-SPTKNHYTSSTSEAVPPPTLTQNQ 332
++ + C+H L + ++ ++++ SPT P T N
Sbjct: 387 SMKQDA-------------CVHDLQAHSKEIYTIKWSPT------------GPATSNPNS 421
Query: 333 AFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD------LGHVETIFDCKFKPDDPNLLA 386
+ L +D + WD + + H E ++ F PD LA
Sbjct: 422 SIMLASAS------------FDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDG-KYLA 468
Query: 387 TASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGG 424
+ SFD + +W+ + + V++ G G I+ + W G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTGG-IFEVCWNARG 505
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 124 bits (310), Expect = 8e-28
Identities = 103/376 (27%), Positives = 162/376 (43%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P KN + E +N A + H+ +DG V ++ K LR
Sbjct: 130 SQQNPPKNREATVNGE--------ENGAHEIN-NHSKPMEIDGDV---EIPPNKATVLR- 176
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 177 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 235 NKDVT-SLDWNSDG-TLLAMGSYDGFARIWT-ENGNLASTLGQH-KGPIFALKWNKKGNY 290
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW N M C T++ ++
Sbjct: 291 VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN---MTFASCS-TDMCIHVCRL 346
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D P+K F GHT +V +KW P +L S SDD T++IW QDAC++ L H+ +
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 590 GLMW--------NTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W N +L S S+D T+++WD +G C T+ H VY + P
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGK 465
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 466 Y-LASGSFDKYVHIWN 480
Score = 90.9 bits (224), Expect = 7e-18
Identities = 69/266 (25%), Positives = 121/266 (45%), Gaps = 35/266 (13%)
Query: 381 DPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIW 440
D LLA S+DG ++W N A T ++G I++L W G ++ G + IW
Sbjct: 246 DGTLLAMGSYDGFARIWTENGNLAS-TLGQHKGPIFALKWNKKGNYVLSAGVDKT-TIIW 303
Query: 441 NVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----------IRTIDGKV 490
+ G+ Q+F H + + W +++ A+CS+D CI ++T G
Sbjct: 304 DAHTGEAKQQFPFHSAPALD-VDW--QNNMTFASCSTD-MCIHVCRLGCDHPVKTFQG-- 357
Query: 491 LHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKW 550
H V W + ++A+ +D ++++ + D + H+ +++ +KW
Sbjct: 358 -----HTNEVNAIKWDPSGM-LLASCSDDMTLKIW--SMKQDACVHDLQAHSKEIYTIKW 409
Query: 551 SPLREG--------ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLI 602
SP +L S S D TVR+WD Q C + L H PV + ++ + YL
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA- 468
Query: 603 SGSWDYTIKVWDTREGTCVDTVYDHG 628
SGS+D + +W+T+ G+ V + G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTG 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 68/271 (25%), Positives = 114/271 (42%), Gaps = 30/271 (11%)
Query: 410 GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQK---GKIIQRFNEH----------GT 456
G+E ++ +W P + +A G+ + A IWN+ + G Q H
Sbjct: 177 GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKY-KHPAAVFGCDWSQNNKDMIAT 515
+ + W+ D +A S DGF I T +G + +H +F W++ +++
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSA 294
Query: 516 GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQD 575
G + T + ++ T + + F H+A V W S S D + + D
Sbjct: 295 GVDKTTI-IWDAHTGEAK--QQFPFHSAPALDVDWQ--NNMTFASCSTDMCIHVCRLGCD 349
Query: 576 ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLT 635
+ GHT V + W+ LL S S D T+K+W ++ CV + H ++Y +
Sbjct: 350 HPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 636 CHPSRPFT--------MASCSRDSTVRLWSL 658
P+ P T +AS S DSTVRLW +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Score = 72.4 bits (176), Expect = 3e-12
Identities = 41/144 (28%), Positives = 70/144 (48%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +D H + I+ K+ P P +LA+ASFD T+++WD+
Sbjct: 380 DMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 440 EQGVCTHTLMKHQEPVYSVAFSPDG-KYLASGSFDKYVHIWNTQSGSLVHSY--QGTGGI 496
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 497 FEVCWNARGDKVGASASDGSVCVL 520
Score = 52.4 bits (124), Expect = 3e-06
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 93/398 (23%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE-------QKVIAKLDSTKG--I 104
++ H+ + +W P + DL ASGS D+ IWN+ E Q V+ G +
Sbjct: 174 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 105 PAS---LSWCWNAE-DVVAFVSHRGPLFIWTISGPDSGVI-VHKDAHSFLSDICMFRWHT 159
P++ S WN++ ++A S+ G IWT +G + + HK I +W
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHK------GPIFALKW-- 284
Query: 160 HQKGK-VVFGHIDGSLSIF--HPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLL 216
++KG V+ +D + I+ H G Q+ D ++ +T + STD +
Sbjct: 285 NKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT---FASCSTDMCI 341
Query: 217 VVNLHYGIRLVDSESLSC---ITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIW 273
V L C + TF V + W PS GM + S L+IW
Sbjct: 342 HVC-----------RLGCDHPVKTFQ--GHTNEVNAIKWDPS--GMLLASCSDDMTLKIW 386
Query: 274 NVSRTTPIDNLKLKKTGFHCLHVLNSPPRKKFSVQ-SPTKNHYTSSTSEAVPPPTLTQNQ 332
++ + C+H L + ++ ++++ SPT P T N
Sbjct: 387 SMKQDA-------------CVHDLQAHSKEIYTIKWSPT------------GPATSNPNS 421
Query: 333 AFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD------LGHVETIFDCKFKPDDPNLLA 386
+ L +D + WD + + H E ++ F PD LA
Sbjct: 422 SIMLASAS------------FDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDG-KYLA 468
Query: 387 TASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGG 424
+ SFD + +W+ + + V++ G G I+ + W G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTGG-IFEVCWNARG 505
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 124 bits (310), Expect = 8e-28
Identities = 103/376 (27%), Positives = 162/376 (43%), Gaps = 49/376 (13%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q+P KN + E +N A + H+ +DG V ++ K LR
Sbjct: 130 SQQNPPKNREATVNGE--------ENGAHEIN-NHSKPMEIDGDV---EIPPNKATVLR- 176
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLT---------------AVYTSPG 410
GH +F C + P +LLA+ S D T ++W++N + + P
Sbjct: 177 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 235 NKDVT-SLDWNSDG-TLLAMGSYDGFARIWT-ENGNLASTLGQH-KGPIFALKWNKKGNY 290
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW N M C T++ ++
Sbjct: 291 VLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN---MTFASCS-TDMCIHVCRL 346
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D P+K F GHT +V +KW P +L S SDD T++IW QDAC++ L H+ +
Sbjct: 347 GCDHPVKTFQGHTNEVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 590 GLMW--------NTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W N +L S S+D T+++WD +G C T+ H VY + P
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGK 465
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 466 Y-LASGSFDKYVHIWN 480
Score = 90.9 bits (224), Expect = 7e-18
Identities = 69/266 (25%), Positives = 121/266 (45%), Gaps = 35/266 (13%)
Query: 381 DPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIW 440
D LLA S+DG ++W N A T ++G I++L W G ++ G + IW
Sbjct: 246 DGTLLAMGSYDGFARIWTENGNLAS-TLGQHKGPIFALKWNKKGNYVLSAGVDKT-TIIW 303
Query: 441 NVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----------IRTIDGKV 490
+ G+ Q+F H + + W +++ A+CS+D CI ++T G
Sbjct: 304 DAHTGEAKQQFPFHSAPALD-VDW--QNNMTFASCSTD-MCIHVCRLGCDHPVKTFQG-- 357
Query: 491 LHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKW 550
H V W + ++A+ +D ++++ + D + H+ +++ +KW
Sbjct: 358 -----HTNEVNAIKWDPSGM-LLASCSDDMTLKIW--SMKQDACVHDLQAHSKEIYTIKW 409
Query: 551 SPLREG--------ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLI 602
SP +L S S D TVR+WD Q C + L H PV + ++ + YL
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA- 468
Query: 603 SGSWDYTIKVWDTREGTCVDTVYDHG 628
SGS+D + +W+T+ G+ V + G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTG 494
Score = 82.8 bits (203), Expect = 2e-15
Identities = 68/271 (25%), Positives = 114/271 (42%), Gaps = 30/271 (11%)
Query: 410 GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQK---GKIIQRFNEH----------GT 456
G+E ++ +W P + +A G+ + A IWN+ + G Q H
Sbjct: 177 GHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 235
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKY-KHPAAVFGCDWSQNNKDMIAT 515
+ + W+ D +A S DGF I T +G + +H +F W++ +++
Sbjct: 236 KDVTSLDWN-SDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSA 294
Query: 516 GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQD 575
G + T + ++ T + + F H+A V W S S D + + D
Sbjct: 295 GVDKTTI-IWDAHTGEAK--QQFPFHSAPALDVDWQ--NNMTFASCSTDMCIHVCRLGCD 349
Query: 576 ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLT 635
+ GHT V + W+ LL S S D T+K+W ++ CV + H ++Y +
Sbjct: 350 HPVKTFQGHTNEVNAIKWDPS-GMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 636 CHPSRPFT--------MASCSRDSTVRLWSL 658
P+ P T +AS S DSTVRLW +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Score = 72.4 bits (176), Expect = 3e-12
Identities = 41/144 (28%), Positives = 70/144 (48%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRDL------GHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +D H + I+ K+ P P +LA+ASFD T+++WD+
Sbjct: 380 DMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDV 439
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 440 EQGVCTHTLMKHQEPVYSVAFSPDG-KYLASGSFDKYVHIWNTQSGSLVHSY--QGTGGI 496
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ + K A+ S C++
Sbjct: 497 FEVCWNARGDKVGASASDGSVCVL 520
Score = 52.4 bits (124), Expect = 3e-06
Identities = 90/398 (22%), Positives = 155/398 (38%), Gaps = 93/398 (23%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAE-------QKVIAKLDSTKG--I 104
++ H+ + +W P + DL ASGS D+ IWN+ E Q V+ G +
Sbjct: 174 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 105 PAS---LSWCWNAE-DVVAFVSHRGPLFIWTISGPDSGVI-VHKDAHSFLSDICMFRWHT 159
P++ S WN++ ++A S+ G IWT +G + + HK I +W
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHK------GPIFALKW-- 284
Query: 160 HQKGK-VVFGHIDGSLSIF--HPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLL 216
++KG V+ +D + I+ H G Q+ D ++ +T + STD +
Sbjct: 285 NKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT---FASCSTDMCI 341
Query: 217 VVNLHYGIRLVDSESLSC---ITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIW 273
V L C + TF V + W PS GM + S L+IW
Sbjct: 342 HVC-----------RLGCDHPVKTFQ--GHTNEVNAIKWDPS--GMLLASCSDDMTLKIW 386
Query: 274 NVSRTTPIDNLKLKKTGFHCLHVLNSPPRKKFSVQ-SPTKNHYTSSTSEAVPPPTLTQNQ 332
++ + C+H L + ++ ++++ SPT P T N
Sbjct: 387 SMKQDA-------------CVHDLQAHSKEIYTIKWSPT------------GPATSNPNS 421
Query: 333 AFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD------LGHVETIFDCKFKPDDPNLLA 386
+ L +D + WD + + H E ++ F PD LA
Sbjct: 422 SIMLASAS------------FDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDG-KYLA 468
Query: 387 TASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGG 424
+ SFD + +W+ + + V++ G G I+ + W G
Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQGTGG-IFEVCWNARG 505
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 120 bits (302), Expect = 6e-27
Identities = 100/376 (26%), Positives = 162/376 (43%), Gaps = 48/376 (12%)
Query: 306 SVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRD 365
S Q KN ++ E +N A ++ H +DG V ++ K LR
Sbjct: 119 SQQGSAKNGENTANGE--------ENGAHTIANNHTDMMEVDGDV---EIPPNKAVVLR- 166
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTS---------------PG 410
GH +F C + P +LLA+ S D T ++W+++ + ++ P
Sbjct: 167 -GHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 411 NEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSK 470
N+ V SL W G +A G+ A IW + G + +H IF + W+ K +
Sbjct: 225 NKDVT-SLDWNSEG-TLLATGSYDGFARIWT-KDGNLASTLGQH-KGPIFALKWNKKGNF 280
Query: 471 RIATCSSDGFCIIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVAT 529
++ I G+ ++ H A DW NN C T++ ++
Sbjct: 281 ILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT---FASCS-TDMCIHVCKL 336
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
D+P+K F GHT +V +KW P +L S SDD T++IW QD C++ L H +
Sbjct: 337 GQDRPIKTFQGHTNEVNAIKWDPTGN-LLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIY 395
Query: 590 GLMWNTEIP--------YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP 641
+ W+ P +L S S+D T+++WD G C+ T+ H VY + P
Sbjct: 396 TIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGR 455
Query: 642 FTMASCSRDSTVRLWS 657
+ +AS S D V +W+
Sbjct: 456 Y-LASGSFDKCVHIWN 470
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/256 (26%), Positives = 118/256 (46%), Gaps = 35/256 (13%)
Query: 384 LLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQ 443
LLAT S+DG ++W + A T ++G I++L W G ++ G + IW+
Sbjct: 239 LLATGSYDGFARIWTKDGNLAS-TLGQHKGPIFALKWNKKGNFILSAGVDKT-TIIWDAH 296
Query: 444 KGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI----------IRTIDGKVLHK 493
G+ Q+F H + + W ++ A+CS+D CI I+T G
Sbjct: 297 TGEAKQQFPFHSAPALD-VDWQSNNT--FASCSTD-MCIHVCKLGQDRPIKTFQG----- 347
Query: 494 YKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPL 553
H V W +++A+ +D ++++ + D + H +++ +KWSP
Sbjct: 348 --HTNEVNAIKWDPTG-NLLASCSDDMTLKIW--SMKQDNCVHDLQAHNKEIYTIKWSPT 402
Query: 554 REG--------ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGS 605
G +L S S D TVR+WD + CI+ L H PV + ++ + YL SGS
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLA-SGS 461
Query: 606 WDYTIKVWDTREGTCV 621
+D + +W+T+ G V
Sbjct: 462 FDKCVHIWNTQTGALV 477
Score = 72.0 bits (175), Expect = 3e-12
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 17/144 (11%)
Query: 354 DMGAKKWDFLRD------LGHVETIFDCKFKPDDPN--------LLATASFDGTIKVWDI 399
DM K W +D H + I+ K+ P P +LA+ASFD T+++WD+
Sbjct: 370 DMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV 429
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+ ++T ++ +YS++++P G +A G+ IWN Q G ++ + GT GI
Sbjct: 430 DRGICIHTLTKHQEPVYSVAFSPDG-RYLASGSFDKCVHIWNTQTGALVHSY--RGTGGI 486
Query: 460 FCIAWSHKDSKRIATCSSDGFCII 483
F + W+ K A+ S C++
Sbjct: 487 FEVCWNAAGDKVGASASDGSVCVL 510
Score = 51.2 bits (121), Expect = 6e-06
Identities = 73/283 (25%), Positives = 116/283 (40%), Gaps = 27/283 (9%)
Query: 351 GLYDMGAKKW----DFLRDLG-HVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAV 405
G YD A+ W + LG H IF K+ N + +A D T +WD +T A
Sbjct: 243 GSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKG-NFILSAGVDKTTIIWDAHTGEAK 301
Query: 406 YTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWS 465
P + + W N A ++ + + + + I+ F H TN + I W
Sbjct: 302 QQFPFHSAPALDVDWQSN--NTFASCSTDMCIHVCKLGQDRPIKTFQGH-TNEVNAIKWD 358
Query: 466 HKDSKRIATCSSDGFCIIRTI--DGKVLHKYKHPAAVFGCDWSQ-----NNKD---MIAT 515
+A+CS D I ++ D V H ++ WS NN + M+A+
Sbjct: 359 -PTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLAS 417
Query: 516 GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQ 574
D+ VR++ V + + H V+ V +SP +G L SGS D V IW+
Sbjct: 418 ASFDSTVRLWDVDRGIC--IHTLTKHQEPVYSVAFSP--DGRYLASGSFDKCVHIWNTQT 473
Query: 575 DACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE 617
A ++ G T + + WN + S S D ++ V D R+
Sbjct: 474 GALVHSYRG-TGGIFEVCWNAAGDKVGASAS-DGSVCVLDLRK 514
Score = 49.7 bits (117), Expect = 2e-05
Identities = 89/394 (22%), Positives = 146/394 (37%), Gaps = 85/394 (21%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKL---------DSTKGI 104
++ H+ + +W P + DL ASGS D+ IWN++E + + +
Sbjct: 164 VLRGHESEVFICAWNPVS-DLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDV 222
Query: 105 PAS---LSWCWNAE-DVVAFVSHRGPLFIWTISGPDSGVI-VHKDAHSFLSDICMFRWHT 159
P++ S WN+E ++A S+ G IWT G + + HK I +W
Sbjct: 223 PSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHK------GPIFALKW-- 274
Query: 160 HQKGK-VVFGHIDGSLSIF--HPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLL 216
++KG ++ +D + I+ H G Q+ AL+ D S +
Sbjct: 275 NKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFH-----------SAPALDVDWQSNNTFA 323
Query: 217 VVNLHYGIRLVDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVS 276
+ I + I TF V + W P+ G + S L+IW++
Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQ--GHTNEVNAIKWDPT--GNLLASCSDDMTLKIWSMK 379
Query: 277 RTTPIDNLKLKKTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSL 336
+ DN C+H +Q+ K YT S P T N +L
Sbjct: 380 Q----DN---------CVH----------DLQAHNKEIYTIKWSPTGPG---TNNPNANL 413
Query: 337 PPGHAVCCFLDGGVGLYDMGAKKWDFLRDL------GHVETIFDCKFKPDDPNLLATASF 390
A +D + WD R + H E ++ F PD LA+ SF
Sbjct: 414 MLASA----------SFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDG-RYLASGSF 462
Query: 391 DGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGG 424
D + +W+ T V++ G G I+ + W G
Sbjct: 463 DKCVHIWNTQTGALVHSYRGTGG-IFEVCWNAAG 495
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 107 bits (266), Expect = 1e-22
Identities = 78/277 (28%), Positives = 128/277 (46%), Gaps = 18/277 (6%)
Query: 383 NLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNV 442
N + + S D T+KVW T + T G+ G ++S N I G++ +WN
Sbjct: 274 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRD---NIIISGSTDRTLKVWNA 330
Query: 443 QKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKYKHPAAVF 501
+ G+ I H T+ + C+ H KR+ + S D + I+ G+ LH A
Sbjct: 331 ETGECIHTLYGH-TSTVRCM---HLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAV 386
Query: 502 GCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSG 561
C Q + + +G D V+V+ T + L GHT +V+ +++ + + SG
Sbjct: 387 RC--VQYDGRRVVSGAYDFMVKVWDPETETC--LHTLQGHTNRVYSLQFDGIH---VVSG 439
Query: 562 SDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCV 621
S D ++R+WD CI+ L GH + G+ I L+SG+ D T+K+WD + G C+
Sbjct: 440 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI---LVSGNADSTVKIWDIKTGQCL 496
Query: 622 DTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
T+ +TC + + S D TV+LW L
Sbjct: 497 QTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 533
Score = 49.3 bits (116), Expect = 2e-05
Identities = 47/229 (20%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGL 425
+GHV + ++ D + + ++D +KVWD T T ++T G+ +YSL + G+
Sbjct: 380 MGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 434
Query: 426 NCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRT 485
+ ++G +W+V+ G I T
Sbjct: 435 HVVSGSLD-TSIRVWDVETGN-----------------------------------CIHT 458
Query: 486 IDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKV 545
+ G H + G + N ++ +G D+ V+++ + T Q L+ G
Sbjct: 459 LTG-------HQSLTSGMELKDN---ILVSGNADSTVKIWDIKTG--QCLQTLQGPNKHQ 506
Query: 546 FHVKWSPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMW 593
V + + + SDDGTV++WD T + N++ + G++W
Sbjct: 507 SAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVW 555
Score = 40.4 bits (93), Expect = 0.011
Identities = 87/403 (21%), Positives = 152/403 (37%), Gaps = 88/403 (21%)
Query: 45 RYNEFKLHAIMSEHKK-TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKL-DSTK 102
R E K ++ H IT + +C + SGS DN + +W+ K + L T
Sbjct: 248 RRGELKSPKVLKGHDDHVITCLQFCGNR---IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 304
Query: 103 GIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQK 162
G+ +S ++++ S L +W ++G +H + CM H H+K
Sbjct: 305 GVWSSQM----RDNIIISGSTDRTLKVW---NAETGECIHTLYGHTSTVRCM---HLHEK 354
Query: 163 GKVVFGHIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHY 222
+VV G D +L ++ HVL V A+ ++ +
Sbjct: 355 -RVVSGSRDATLRVWDIETGQCLHVLMGH----------VAAVRCVQYDGRRVVSGAYDF 403
Query: 223 GIRLVDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPID 282
+++ D E+ +C+ T L V L + G+ + S +R+W+V
Sbjct: 404 MVKVWDPETETCLHT--LQGHTNRVYSLQF----DGIHVVSGSLDTSIRVWDV------- 450
Query: 283 NLKLKKTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAV 342
+TG +C+H L H + ++ + L A
Sbjct: 451 -----ETG-NCIHTLT--------------GHQSLTSGMELKDNILVSGNA--------- 481
Query: 343 CCFLDGGVGLYDMGAKKWDFLRDL----GHVETIFDCKFKPDDPNLLATASFDGTIKVWD 398
D V ++D+ K L+ L H + +F + N + T+S DGT+K+WD
Sbjct: 482 ----DSTVKIWDI--KTGQCLQTLQGPNKHQSAVTCLQF---NKNFVITSSDDGTVKLWD 532
Query: 399 INT-----LTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNG 436
+ T S G+ GV++ + + L C G SRNG
Sbjct: 533 LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVG--SRNG 573
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 107 bits (266), Expect = 1e-22
Identities = 78/277 (28%), Positives = 128/277 (46%), Gaps = 18/277 (6%)
Query: 383 NLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNV 442
N + + S D T+KVW T + T G+ G ++S N I G++ +WN
Sbjct: 392 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRD---NIIISGSTDRTLKVWNA 448
Query: 443 QKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKYKHPAAVF 501
+ G+ I H T+ + C+ H KR+ + S D + I+ G+ LH A
Sbjct: 449 ETGECIHTLYGH-TSTVRCM---HLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAV 504
Query: 502 GCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSG 561
C Q + + +G D V+V+ T + L GHT +V+ +++ + + SG
Sbjct: 505 RC--VQYDGRRVVSGAYDFMVKVWDPETETC--LHTLQGHTNRVYSLQFDGIH---VVSG 557
Query: 562 SDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCV 621
S D ++R+WD CI+ L GH + G+ I L+SG+ D T+K+WD + G C+
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI---LVSGNADSTVKIWDIKTGQCL 614
Query: 622 DTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
T+ +TC + + S D TV+LW L
Sbjct: 615 QTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 651
Score = 49.3 bits (116), Expect = 2e-05
Identities = 47/229 (20%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGL 425
+GHV + ++ D + + ++D +KVWD T T ++T G+ +YSL + G+
Sbjct: 498 MGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 552
Query: 426 NCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRT 485
+ ++G +W+V+ G I T
Sbjct: 553 HVVSGSLD-TSIRVWDVETGN-----------------------------------CIHT 576
Query: 486 IDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKV 545
+ G H + G + N ++ +G D+ V+++ + T Q L+ G
Sbjct: 577 LTG-------HQSLTSGMELKDN---ILVSGNADSTVKIWDIKTG--QCLQTLQGPNKHQ 624
Query: 546 FHVKWSPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMW 593
V + + + SDDGTV++WD T + N++ + G++W
Sbjct: 625 SAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVW 673
Score = 40.4 bits (93), Expect = 0.011
Identities = 87/403 (21%), Positives = 152/403 (37%), Gaps = 88/403 (21%)
Query: 45 RYNEFKLHAIMSEHKK-TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKL-DSTK 102
R E K ++ H IT + +C + SGS DN + +W+ K + L T
Sbjct: 366 RRGELKSPKVLKGHDDHVITCLQFCGNR---IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 422
Query: 103 GIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQK 162
G+ +S ++++ S L +W ++G +H + CM H H+K
Sbjct: 423 GVWSSQM----RDNIIISGSTDRTLKVW---NAETGECIHTLYGHTSTVRCM---HLHEK 472
Query: 163 GKVVFGHIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHY 222
+VV G D +L ++ HVL V A+ ++ +
Sbjct: 473 -RVVSGSRDATLRVWDIETGQCLHVLMGH----------VAAVRCVQYDGRRVVSGAYDF 521
Query: 223 GIRLVDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPID 282
+++ D E+ +C+ T L V L + G+ + S +R+W+V
Sbjct: 522 MVKVWDPETETCLHT--LQGHTNRVYSLQF----DGIHVVSGSLDTSIRVWDV------- 568
Query: 283 NLKLKKTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAV 342
+TG +C+H L H + ++ + L A
Sbjct: 569 -----ETG-NCIHTLT--------------GHQSLTSGMELKDNILVSGNA--------- 599
Query: 343 CCFLDGGVGLYDMGAKKWDFLRDL----GHVETIFDCKFKPDDPNLLATASFDGTIKVWD 398
D V ++D+ K L+ L H + +F + N + T+S DGT+K+WD
Sbjct: 600 ----DSTVKIWDI--KTGQCLQTLQGPNKHQSAVTCLQF---NKNFVITSSDDGTVKLWD 650
Query: 399 INT-----LTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNG 436
+ T S G+ GV++ + + L C G SRNG
Sbjct: 651 LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVG--SRNG 691
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 107 bits (266), Expect = 1e-22
Identities = 78/277 (28%), Positives = 128/277 (46%), Gaps = 18/277 (6%)
Query: 383 NLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNV 442
N + + S D T+KVW T + T G+ G ++S N I G++ +WN
Sbjct: 312 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRD---NIIISGSTDRTLKVWNA 368
Query: 443 QKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKYKHPAAVF 501
+ G+ I H T+ + C+ H KR+ + S D + I+ G+ LH A
Sbjct: 369 ETGECIHTLYGH-TSTVRCM---HLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAV 424
Query: 502 GCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSG 561
C Q + + +G D V+V+ T + L GHT +V+ +++ + + SG
Sbjct: 425 RC--VQYDGRRVVSGAYDFMVKVWDPETETC--LHTLQGHTNRVYSLQFDGIH---VVSG 477
Query: 562 SDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCV 621
S D ++R+WD CI+ L GH + G+ I L+SG+ D T+K+WD + G C+
Sbjct: 478 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNI---LVSGNADSTVKIWDIKTGQCL 534
Query: 622 DTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
T+ +TC + + S D TV+LW L
Sbjct: 535 QTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 571
Score = 49.3 bits (116), Expect = 2e-05
Identities = 47/229 (20%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGL 425
+GHV + ++ D + + ++D +KVWD T T ++T G+ +YSL + G+
Sbjct: 418 MGHVAAVRCVQY---DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 472
Query: 426 NCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRT 485
+ ++G +W+V+ G I T
Sbjct: 473 HVVSGSLD-TSIRVWDVETGN-----------------------------------CIHT 496
Query: 486 IDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKV 545
+ G H + G + N ++ +G D+ V+++ + T Q L+ G
Sbjct: 497 LTG-------HQSLTSGMELKDN---ILVSGNADSTVKIWDIKTG--QCLQTLQGPNKHQ 544
Query: 546 FHVKWSPLREGILCSGSDDGTVRIWDY-TQDACINILNGHTAPVRGLMW 593
V + + + SDDGTV++WD T + N++ + G++W
Sbjct: 545 SAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVW 593
Score = 40.4 bits (93), Expect = 0.011
Identities = 87/403 (21%), Positives = 152/403 (37%), Gaps = 88/403 (21%)
Query: 45 RYNEFKLHAIMSEHKK-TITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKL-DSTK 102
R E K ++ H IT + +C + SGS DN + +W+ K + L T
Sbjct: 286 RRGELKSPKVLKGHDDHVITCLQFCGNR---IVSGSDDNTLKVWSAVTGKCLRTLVGHTG 342
Query: 103 GIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQK 162
G+ +S ++++ S L +W ++G +H + CM H H+K
Sbjct: 343 GVWSSQM----RDNIIISGSTDRTLKVW---NAETGECIHTLYGHTSTVRCM---HLHEK 392
Query: 163 GKVVFGHIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHY 222
+VV G D +L ++ HVL V A+ ++ +
Sbjct: 393 -RVVSGSRDATLRVWDIETGQCLHVLMGH----------VAAVRCVQYDGRRVVSGAYDF 441
Query: 223 GIRLVDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPID 282
+++ D E+ +C+ T L V L + G+ + S +R+W+V
Sbjct: 442 MVKVWDPETETCLHT--LQGHTNRVYSLQF----DGIHVVSGSLDTSIRVWDV------- 488
Query: 283 NLKLKKTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAV 342
+TG +C+H L H + ++ + L A
Sbjct: 489 -----ETG-NCIHTLT--------------GHQSLTSGMELKDNILVSGNA--------- 519
Query: 343 CCFLDGGVGLYDMGAKKWDFLRDL----GHVETIFDCKFKPDDPNLLATASFDGTIKVWD 398
D V ++D+ K L+ L H + +F + N + T+S DGT+K+WD
Sbjct: 520 ----DSTVKIWDI--KTGQCLQTLQGPNKHQSAVTCLQF---NKNFVITSSDDGTVKLWD 570
Query: 399 INT-----LTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNG 436
+ T S G+ GV++ + + L C G SRNG
Sbjct: 571 LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVG--SRNG 611
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 100 bits (248), Expect = 1e-20
Identities = 70/250 (28%), Positives = 120/250 (48%), Gaps = 11/250 (4%)
Query: 372 IFDCKFKPDDPNLLATASFDGTIKVWDINTLTA---VYTSPGNEGVIYSLSWAPG-GLNC 427
+FD + ++ ++L T S DG++++WD VY E +YS+ W+ G
Sbjct: 70 LFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQE--VYSVDWSQTRGEQL 127
Query: 428 IAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTID 487
+ G+ +W+ GK + F H + I+ WS A+ S D I +
Sbjct: 128 VVSGSWDQTVKLWDPTVGKSLCTFRGHESI-IYSTIWSPHIPGCFASASGDQTLRIWDVK 186
Query: 488 --GKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKV 545
G + H A + CDW + N++++ TG D ++R + + QP+ GHT +
Sbjct: 187 AAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVR-QPVFELLGHTYAI 245
Query: 546 FHVKWSPLREGILCSGSDDGTVRIWDYTQ-DACINILNGHTAPVRGLMWNTEIPYLLISG 604
VK+SP +L S S D TVR W++++ D+ + + HT GL ++ + P +
Sbjct: 246 RRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADC 305
Query: 605 SWDYTIKVWD 614
SWD TIK++D
Sbjct: 306 SWDETIKIYD 315
Score = 91.7 bits (226), Expect = 4e-18
Identities = 80/303 (26%), Positives = 122/303 (40%), Gaps = 36/303 (11%)
Query: 408 SPGNEGVIYSLS-WAPGGLNCIAG---GTSRNGAFIWNVQKGKIIQRFNEHGTN-GIFCI 462
+PG G S + PG L C G + G + ++ F N G+F +
Sbjct: 14 TPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDV 73
Query: 463 AWSHKDSKRIATCSSDGFCIIRTIDGKV--LHKYK-HPAAVFGCDWSQNN-KDMIATGCE 518
WS + + TCS DG + L YK H V+ DWSQ + ++ +G
Sbjct: 74 TWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSW 133
Query: 519 DTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACI 578
D V+++ L F GH + ++ WSP G S S D T+RIWD
Sbjct: 134 DQTVKLWDPTVGKS--LCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVR 191
Query: 579 NILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE-GTCVDTVYDHGADVYGLTCH 637
++ H A + W LL++G+ D +++ WD R V + H + +
Sbjct: 192 IVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFS 251
Query: 638 PSRPFTMASCSRDSTVRLWSLT---------------------ALVTPVQINILADRSWE 676
P +ASCS D TVR W+ + +L +P Q+ AD SW+
Sbjct: 252 PFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQV---ADCSWD 308
Query: 677 EII 679
E I
Sbjct: 309 ETI 311
Score = 76.3 bits (186), Expect = 2e-13
Identities = 50/175 (28%), Positives = 83/175 (47%), Gaps = 8/175 (4%)
Query: 545 VFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC-INILNGHTAPVRGLMWN-TEIPYLLI 602
+F V WS E +L + S DG++++WD + A + + H V + W+ T L++
Sbjct: 70 LFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVV 129
Query: 603 SGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA-- 660
SGSWD T+K+WD G + T H + +Y P P AS S D T+R+W + A
Sbjct: 130 SGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAG 189
Query: 661 --LVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANS 713
+V P + W + N + + L G R++RQ + +L ++
Sbjct: 190 VRIVIPAHQAEILSCDWCKY--NENLLVTGAVDCSLRGWDLRNVRQPVFELLGHT 242
Score = 37.4 bits (85), Expect = 0.094
Identities = 19/61 (31%), Positives = 29/61 (47%)
Query: 58 HKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDV 117
H+ I + W PH P FAS S D + IW+V V + + + S WC E++
Sbjct: 154 HESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENL 213
Query: 118 V 118
+
Sbjct: 214 L 214
Score = 37.0 bits (84), Expect = 0.12
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 5/122 (4%)
Query: 54 IMSEHKKTITAISWCP-HNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCW 112
+ EH + + ++ W L SGS D V +W+ K + + I S W
Sbjct: 106 VYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSP 165
Query: 113 NAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDG 172
+ A S L IW + +GV + AH ++I W + + +V G +D
Sbjct: 166 HIPGCFASASGDQTLRIWDVKA--AGVRIVIPAHQ--AEILSCDWCKYNENLLVTGAVDC 221
Query: 173 SL 174
SL
Sbjct: 222 SL 223
Score = 32.7 bits (73), Expect = 2.3
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNV--AEQKVIAKLDSTKGIPASLSWC 111
++ H+ I + WC +N +L +G+ D + W++ Q V L T I
Sbjct: 193 VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSP 252
Query: 112 WNAEDVVAFVSHRGPLFIWTISGPDS 137
++A V+A S+ + W S PDS
Sbjct: 253 FHA-SVLASCSYDFTVRFWNFSKPDS 277
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 95.9 bits (237), Expect = 2e-19
Identities = 81/325 (24%), Positives = 145/325 (44%), Gaps = 28/325 (8%)
Query: 344 CFLDGGVGLYDMGAKKWDF-----LRDL-GHVETIFDCKFKPDDPNLLATASFDGTIKVW 397
CF+ G YD K WD L L GH ++ F + +AT SFD T K+W
Sbjct: 106 CFITGS---YDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLW 162
Query: 398 DINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTN 457
+ T +T G+ I LS+ P +A G+ A +W++Q G+ + H
Sbjct: 163 SVETGKCYHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAE 221
Query: 458 GIFCIAWSHKDSKRIATCSSDGFCII------RTIDGKVLHKYKHPAAVFGCDWSQNNKD 511
I +++ + RI T S D ++ R ++ + H + +A F D S
Sbjct: 222 -IISLSF-NTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCS----- 274
Query: 512 MIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWD 571
+I TG D +++ ++ + + +GH ++ + + ++ + S DGT RI+
Sbjct: 275 LILTGSMDKTCKLW--DATNGKCVATLTGHDDEILDSCFDYTGK-LIATASADGTARIFS 331
Query: 572 YTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADV 631
CI L GH + + +N + +LL +GS D T ++WD + G C+ + H ++
Sbjct: 332 AATRKCIAKLEGHEGEISKISFNPQGNHLL-TGSSDKTARIWDAQTGQCLQVLEGHTDEI 390
Query: 632 YGLTCHPSRPFTMASCSRDSTVRLW 656
+ + + S+D+T R+W
Sbjct: 391 FSCAFNYKGNIVITG-SKDNTCRIW 414
Score = 88.2 bits (217), Expect = 5e-17
Identities = 80/289 (27%), Positives = 119/289 (41%), Gaps = 23/289 (7%)
Query: 333 AFSLPPGHAVCCFLDGGVGLYDMGAKKWD------FLRDLGHVETIFDCKFKPDDPNLLA 386
AF+ P G + G +D K W + GH I F P L+A
Sbjct: 141 AFNNPYGDKIA------TGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS-TLVA 193
Query: 387 TASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGK 446
T S D T K+WDI VYT G+ I SLS+ G I G +W+ G+
Sbjct: 194 TGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHT-VVVWDADTGR 252
Query: 447 IIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFC-IIRTIDGK-VLHKYKHPAAVFGCD 504
+ H A + D I T S D C + +GK V H +
Sbjct: 253 KVNILIGHCAE--ISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSC 310
Query: 505 WSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDD 564
+ K +IAT D R++ AT + + GH ++ + ++P +L +GS D
Sbjct: 311 FDYTGK-LIATASADGTARIFSAATR--KCIAKLEGHEGEISKISFNPQGNHLL-TGSSD 366
Query: 565 GTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 613
T RIWD C+ +L GHT + +N + ++I+GS D T ++W
Sbjct: 367 KTARIWDAQTGQCLQVLEGHTDEIFSCAFNYK-GNIVITGSKDNTCRIW 414
Score = 60.5 bits (145), Expect = 1e-08
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Query: 560 SGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGT 619
+GS D T ++WD +N L GH V + +N + +GS+D T K+W G
Sbjct: 109 TGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGK 168
Query: 620 CVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
C T H A++ L+ +P +A+ S D+T +LW +
Sbjct: 169 CYHTFRGHTAEIVCLSFNPQSTL-VATGSMDTTAKLWDI 206
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 580 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPS 639
+L H P+ + N I+GS+D T K+WDT G ++T+ H VY + +
Sbjct: 87 VLKAHILPLTNVALNKS-GSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNP 145
Query: 640 RPFTMASCSRDSTVRLWSL 658
+A+ S D T +LWS+
Sbjct: 146 YGDKIATGSFDKTCKLWSV 164
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 95.1 bits (235), Expect = 4e-19
Identities = 212/1058 (20%), Positives = 376/1058 (35%), Gaps = 259/1058 (24%)
Query: 23 AASGDRFAYCATLAIYIYQLDHRYNE------FKLHAIMSEHKKTITAISWCPH--NPDL 74
A G F + A ++++ ++ E F++ + H + ++ ++ H +L
Sbjct: 22 AVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNL 81
Query: 75 FASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAFVSHRGPLFIWTISG 134
A+ S D V IW+V + V+ + + ++L W +D++ +G +F + +
Sbjct: 82 CATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNR 141
Query: 135 PDSGVIVHKDAHSFLSDICMF--RWHTHQKGKVVFGHIDGSLSIFHPGNKNQK-HVLRPE 191
DS H F+ +F H + V G+ DG + I K + H LR
Sbjct: 142 NDS-------QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLR-- 192
Query: 192 SLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNLPSAAASVQCLA 251
+D + ++ W PL + L +N ++ + IT N +A
Sbjct: 193 -----GHDDEIHSIAWCPLPGEDCLSINQE------ETSEEAEITNGN---------AVA 232
Query: 252 WVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKL--------------KKTGFHCLHVL 297
P G ++ S+ +RIW+ SR + LKL K+ + LH
Sbjct: 233 QAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWP 292
Query: 298 NSPPRK-----------KFSVQSPTKNHYT--SSTSEAVPPPTLTQNQA---FSLPPGHA 341
++ P + ++ + + YT S++SE QN + F+L P
Sbjct: 293 SNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEG-------QNHSRIVFNLCPLQT 345
Query: 342 -------VCCFLDGGVGLYDMGAKKWDF-LRDLGHVETIFDCKFKPDDPNLLATASFDGT 393
+ +D V +D+ + + L LG + F D LA DG
Sbjct: 346 EDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFA--YSLAFSSVDIGSLAIGVGDGM 403
Query: 394 IKVWDINTLTAVYTSP----GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQ 449
I+VW+ ++ Y G + + +L W P C+A GT +++ K Q
Sbjct: 404 IRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQ 463
Query: 450 RFNEHGTNGIFCIAWS------------HKDSKRIATCSSDG--------------FCII 483
+ + ++ +AW + S + +C +G F I
Sbjct: 464 ISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDIN 523
Query: 484 RTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV------------------- 524
+ I KYK P W + K M A G ED ++ +
Sbjct: 524 KLIRDTNSIKYKLPVHT-EISWKADGKIM-ALGNEDGSIEIFQIPNLKLICTIQQHHKLV 581
Query: 525 ----------------YYVATSSD------------------------QPLKVFSGHTAK 544
Y +A+ S+ +P + SGHTAK
Sbjct: 582 NTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAK 641
Query: 545 VFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISG 604
+ V WSP +G L S S DGT ++WD ++ + GH + + W+ P + SG
Sbjct: 642 ITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSG 701
Query: 605 SWDYTIKVWDTREGTCVDTVYDHGADVYGLTC------HPSRPFTMASCSRDSTVRLWSL 658
+ D+ + W T ++ DH G S+P + T+R
Sbjct: 702 ADDFCVHKWLT-------SMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKPTLR---- 750
Query: 659 TALVTPVQINILADRSWEEIIGNT-------------DYAIEPGTP----------PLLC 695
TPV++ + E + N+ + A EP P P++C
Sbjct: 751 ----TPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVIC 806
Query: 696 GKVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLP----- 750
VS E K+T N++V L+ PP + K + SLLP
Sbjct: 807 TPVSSGF--EKSKVTINNKVILLK-----KEPPKEKPE----TLIKKRKARSLLPLSTSL 855
Query: 751 QNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGG--GIGVPAKEERLKEAAEI----HLR 804
+ K +H L+ ++EL + +G+ L +I HL
Sbjct: 856 DHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLE 915
Query: 805 LGQIQRYCELMVELGE--------------WDKALSIAPGVSVKYWKKLMQRRADQL-IQ 849
G + + +LM+ G+ D +++AP W ++ A QL Q
Sbjct: 916 NGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQ 975
Query: 850 EDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQA 887
+ + ++I V + V S +EA+ +A+A
Sbjct: 976 DQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKA 1013
Score = 75.9 bits (185), Expect = 2e-13
Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 46/327 (14%)
Query: 310 PTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRDL-GH 368
P+ N Y + S+AVP F +V G G + + +L GH
Sbjct: 10 PSPNWYCARCSDAVP------GGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGH 63
Query: 369 VETI--FDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
E + F P NL AT+S DGT+K+WD+ T T V ++ I +L W+P +
Sbjct: 64 TERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKD 123
Query: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 486
I G + F + + F E T IFC+ S +A DG +I I
Sbjct: 124 LIVSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
Query: 487 D--GKVLHKYK-HPAAVFGCDWSQ-NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHT 542
G+V+H+ + H + W +D ++ E+T+ + ++ +G+
Sbjct: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETS-----------EEAEITNGNA 230
Query: 543 AKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRG----------- 590
V +P+ +G L +GS D T+RIW ++ + IL RG
Sbjct: 231 -----VAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERL 285
Query: 591 ---LMWNTEIPYLLISGSWDYTIKVWD 614
L W + P L+S + + WD
Sbjct: 286 WLTLHWPSNQPTQLVSSCFGGELLQWD 312
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 89.7 bits (221), Expect = 2e-17
Identities = 76/292 (26%), Positives = 131/292 (44%), Gaps = 39/292 (13%)
Query: 381 DPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIW 440
D + + D TIK+WD NTL G+ G + L + I G+S + +W
Sbjct: 276 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDE---RVIITGSSDSTVRVW 332
Query: 441 NVQKGKIIQRFNEHGTNGIFCIAWSHK--DSKRIATCSSDGFCIIRTIDGKVLHKYK--- 495
+V G+++ H C A H ++ + TCS D + + +
Sbjct: 333 DVNTGEMLNTLIHH------CEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 386
Query: 496 --HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPL 553
H AAV D+ I + D ++V+ TS+ + ++ +GH + +++
Sbjct: 387 VGHRAAVNVVDFDDK---YIVSASGDRTIKVWN--TSTCEFVRTLNGHKRGIACLQY--- 438
Query: 554 REGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 613
R+ ++ SGS D T+R+WD AC+ +L GH VR + ++ + ++SG++D IKVW
Sbjct: 439 RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK---RIVSGAYDGKIKVW 495
Query: 614 D--------TREGT-CVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
D GT C+ T+ +H V+ L F + S S D T+ +W
Sbjct: 496 DLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFD---EFQIVSSSHDDTILIW 544
Score = 64.7 bits (156), Expect = 6e-10
Identities = 47/155 (30%), Positives = 77/155 (49%), Gaps = 14/155 (9%)
Query: 507 QNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGT 566
Q ++ +I TG D+ VRV+ V T + L H V H++++ G++ + S D +
Sbjct: 314 QYDERVIITGSSDSTVRVWDVNTG--EMLNTLIHHCEAVLHLRFN---NGMMVTCSKDRS 368
Query: 567 VRIWDYTQDACIN---ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDT 623
+ +WD I +L GH A V + ++ + ++S S D TIKVW+T V T
Sbjct: 369 IAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEFVRT 425
Query: 624 VYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
+ H G+ C R + S S D+T+RLW +
Sbjct: 426 LNGHKR---GIACLQYRDRLVVSGSSDNTIRLWDI 457
Score = 63.5 bits (153), Expect = 1e-09
Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 541 HTAKVFHVKWSPLREGILC---------SGSDDGTVRIWDYTQDACINILNGHTAPVRGL 591
H+ + H + S +G+ C SG D T++IWD C IL GHT V L
Sbjct: 255 HSLQRIHCR-SETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCL 313
Query: 592 MWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDS 651
++ + +I+GS D T++VWD G ++T+ H V L + M +CS+D
Sbjct: 314 QYDERV---IITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGM---MVTCSKDR 367
Query: 652 TVRLWSLTA 660
++ +W + +
Sbjct: 368 SIAVWDMAS 376
>gi|16117783 beta-transducin repeat containing protein isoform 1
[Homo sapiens]
Length = 605
Score = 89.7 bits (221), Expect = 2e-17
Identities = 76/292 (26%), Positives = 131/292 (44%), Gaps = 39/292 (13%)
Query: 381 DPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIW 440
D + + D TIK+WD NTL G+ G + L + I G+S + +W
Sbjct: 312 DDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDE---RVIITGSSDSTVRVW 368
Query: 441 NVQKGKIIQRFNEHGTNGIFCIAWSHK--DSKRIATCSSDGFCIIRTIDGKVLHKYK--- 495
+V G+++ H C A H ++ + TCS D + + +
Sbjct: 369 DVNTGEMLNTLIHH------CEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVL 422
Query: 496 --HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPL 553
H AAV D+ I + D ++V+ TS+ + ++ +GH + +++
Sbjct: 423 VGHRAAVNVVDFDDK---YIVSASGDRTIKVWN--TSTCEFVRTLNGHKRGIACLQY--- 474
Query: 554 REGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVW 613
R+ ++ SGS D T+R+WD AC+ +L GH VR + ++ + ++SG++D IKVW
Sbjct: 475 RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK---RIVSGAYDGKIKVW 531
Query: 614 D--------TREGT-CVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
D GT C+ T+ +H V+ L F + S S D T+ +W
Sbjct: 532 DLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFD---EFQIVSSSHDDTILIW 580
Score = 64.7 bits (156), Expect = 6e-10
Identities = 47/155 (30%), Positives = 77/155 (49%), Gaps = 14/155 (9%)
Query: 507 QNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGT 566
Q ++ +I TG D+ VRV+ V T + L H V H++++ G++ + S D +
Sbjct: 350 QYDERVIITGSSDSTVRVWDVNTG--EMLNTLIHHCEAVLHLRFN---NGMMVTCSKDRS 404
Query: 567 VRIWDYTQDACIN---ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDT 623
+ +WD I +L GH A V + ++ + ++S S D TIKVW+T V T
Sbjct: 405 IAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWNTSTCEFVRT 461
Query: 624 VYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
+ H G+ C R + S S D+T+RLW +
Sbjct: 462 LNGHKR---GIACLQYRDRLVVSGSSDNTIRLWDI 493
Score = 63.5 bits (153), Expect = 1e-09
Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 541 HTAKVFHVKWSPLREGILC---------SGSDDGTVRIWDYTQDACINILNGHTAPVRGL 591
H+ + H + S +G+ C SG D T++IWD C IL GHT V L
Sbjct: 291 HSLQRIHCR-SETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCL 349
Query: 592 MWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDS 651
++ + +I+GS D T++VWD G ++T+ H V L + M +CS+D
Sbjct: 350 QYDERV---IITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGM---MVTCSKDR 403
Query: 652 TVRLWSLTA 660
++ +W + +
Sbjct: 404 SIAVWDMAS 412
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 87.8 bits (216), Expect = 6e-17
Identities = 68/283 (24%), Positives = 126/283 (44%), Gaps = 41/283 (14%)
Query: 391 DGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQR 450
D +IK+WD +L + G+ G + L + I G+S + +W+V G+++
Sbjct: 259 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE---RVIVTGSSDSTVRVWDVNTGEVLNT 315
Query: 451 FNEHG--------TNGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFG 502
H +NG+ + S+ + R + G H AAV
Sbjct: 316 LIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVG-------HRAAVNV 368
Query: 503 CDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGS 562
D+ I + D ++V+ +TS+ + ++ +GH + +++ R+ ++ SGS
Sbjct: 369 VDFDDK---YIVSASGDRTIKVW--STSTCEFVRTLNGHKRGIACLQY---RDRLVVSGS 420
Query: 563 DDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREG---- 618
D T+R+WD AC+ +L GH VR + ++ + ++SG++D IKVWD +
Sbjct: 421 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK---RIVSGAYDGKIKVWDLQAALDPR 477
Query: 619 -----TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
C+ T+ +H V+ L F + S S D T+ +W
Sbjct: 478 APASTLCLRTLVEHSGRVFRLQFD---EFQIISSSHDDTILIW 517
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 14/155 (9%)
Query: 507 QNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGT 566
Q ++ +I TG D+ VRV+ V T + L H V H+++S G++ + S D +
Sbjct: 287 QYDERVIVTGSSDSTVRVWDVNTG--EVLNTLIHHNEAVLHLRFS---NGLMVTCSKDRS 341
Query: 567 VRIWDYTQDACIN---ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDT 623
+ +WD I +L GH A V + ++ + ++S S D TIKVW T V T
Sbjct: 342 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEFVRT 398
Query: 624 VYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
+ H G+ C R + S S D+T+RLW +
Sbjct: 399 LNGHKR---GIACLQYRDRLVVSGSSDNTIRLWDI 430
Score = 65.5 bits (158), Expect = 3e-10
Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 6/103 (5%)
Query: 558 LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE 617
+ SG D +++IWD T C+ +L GHT V L ++ + +++GS D T++VWD
Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERV---IVTGSSDSTVRVWDVNT 309
Query: 618 GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
G ++T+ H V L M +CS+D ++ +W + +
Sbjct: 310 GEVLNTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMAS 349
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/236 (24%), Positives = 96/236 (40%), Gaps = 49/236 (20%)
Query: 339 GHAVCCFLDGGVGLYDMGAKKWDFLRDL--GHVETIFDCKFKPDDPNLLATASFDGTIKV 396
G V C D + ++DM + LR + GH + F D + +AS D TIKV
Sbjct: 331 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKV 387
Query: 397 WDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGT 456
W +T V T G++ I L + + G+S N +W+++ G ++ H
Sbjct: 388 WSTSTCEFVRTLNGHKRGIACLQYRD---RLVVSGSSDNTIRLWDIECGACLRVLEGH-E 443
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATG 516
+ CI + D+KRI + + DG I+ D + + PA +T
Sbjct: 444 ELVRCIRF---DNKRIVSGAYDG--KIKVWDLQAALDPRAPA---------------STL 483
Query: 517 CEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDY 572
C L+ H+ +VF +++ + + S S D T+ IWD+
Sbjct: 484 C-----------------LRTLVEHSGRVFRLQFDEFQ---IISSSHDDTILIWDF 519
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 87.8 bits (216), Expect = 6e-17
Identities = 68/283 (24%), Positives = 126/283 (44%), Gaps = 41/283 (14%)
Query: 391 DGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQR 450
D +IK+WD +L + G+ G + L + I G+S + +W+V G+++
Sbjct: 225 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE---RVIVTGSSDSTVRVWDVNTGEVLNT 281
Query: 451 FNEHG--------TNGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFG 502
H +NG+ + S+ + R + G H AAV
Sbjct: 282 LIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVG-------HRAAVNV 334
Query: 503 CDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGS 562
D+ I + D ++V+ +TS+ + ++ +GH + +++ R+ ++ SGS
Sbjct: 335 VDFDDK---YIVSASGDRTIKVW--STSTCEFVRTLNGHKRGIACLQY---RDRLVVSGS 386
Query: 563 DDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREG---- 618
D T+R+WD AC+ +L GH VR + ++ + ++SG++D IKVWD +
Sbjct: 387 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK---RIVSGAYDGKIKVWDLQAALDPR 443
Query: 619 -----TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
C+ T+ +H V+ L F + S S D T+ +W
Sbjct: 444 APASTLCLRTLVEHSGRVFRLQFD---EFQIISSSHDDTILIW 483
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 14/155 (9%)
Query: 507 QNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGT 566
Q ++ +I TG D+ VRV+ V T + L H V H+++S G++ + S D +
Sbjct: 253 QYDERVIVTGSSDSTVRVWDVNTG--EVLNTLIHHNEAVLHLRFS---NGLMVTCSKDRS 307
Query: 567 VRIWDYTQDACIN---ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDT 623
+ +WD I +L GH A V + ++ + ++S S D TIKVW T V T
Sbjct: 308 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEFVRT 364
Query: 624 VYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
+ H G+ C R + S S D+T+RLW +
Sbjct: 365 LNGHKR---GIACLQYRDRLVVSGSSDNTIRLWDI 396
Score = 65.5 bits (158), Expect = 3e-10
Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 6/103 (5%)
Query: 558 LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE 617
+ SG D +++IWD T C+ +L GHT V L ++ + +++GS D T++VWD
Sbjct: 219 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERV---IVTGSSDSTVRVWDVNT 275
Query: 618 GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
G ++T+ H V L M +CS+D ++ +W + +
Sbjct: 276 GEVLNTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMAS 315
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/236 (24%), Positives = 96/236 (40%), Gaps = 49/236 (20%)
Query: 339 GHAVCCFLDGGVGLYDMGAKKWDFLRDL--GHVETIFDCKFKPDDPNLLATASFDGTIKV 396
G V C D + ++DM + LR + GH + F D + +AS D TIKV
Sbjct: 297 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKV 353
Query: 397 WDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGT 456
W +T V T G++ I L + + G+S N +W+++ G ++ H
Sbjct: 354 WSTSTCEFVRTLNGHKRGIACLQYRD---RLVVSGSSDNTIRLWDIECGACLRVLEGH-E 409
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATG 516
+ CI + D+KRI + + DG I+ D + + PA +T
Sbjct: 410 ELVRCIRF---DNKRIVSGAYDG--KIKVWDLQAALDPRAPA---------------STL 449
Query: 517 CEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDY 572
C L+ H+ +VF +++ + + S S D T+ IWD+
Sbjct: 450 C-----------------LRTLVEHSGRVFRLQFDEFQ---IISSSHDDTILIWDF 485
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 87.8 bits (216), Expect = 6e-17
Identities = 68/283 (24%), Positives = 126/283 (44%), Gaps = 41/283 (14%)
Query: 391 DGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQR 450
D +IK+WD +L + G+ G + L + I G+S + +W+V G+++
Sbjct: 246 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE---RVIVTGSSDSTVRVWDVNTGEVLNT 302
Query: 451 FNEHG--------TNGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFG 502
H +NG+ + S+ + R + G H AAV
Sbjct: 303 LIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVG-------HRAAVNV 355
Query: 503 CDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGS 562
D+ I + D ++V+ +TS+ + ++ +GH + +++ R+ ++ SGS
Sbjct: 356 VDFDDK---YIVSASGDRTIKVW--STSTCEFVRTLNGHKRGIACLQY---RDRLVVSGS 407
Query: 563 DDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREG---- 618
D T+R+WD AC+ +L GH VR + ++ + ++SG++D IKVWD +
Sbjct: 408 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK---RIVSGAYDGKIKVWDLQAALDPR 464
Query: 619 -----TCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
C+ T+ +H V+ L F + S S D T+ +W
Sbjct: 465 APASTLCLRTLVEHSGRVFRLQFD---EFQIISSSHDDTILIW 504
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 14/155 (9%)
Query: 507 QNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGT 566
Q ++ +I TG D+ VRV+ V T + L H V H+++S G++ + S D +
Sbjct: 274 QYDERVIVTGSSDSTVRVWDVNTG--EVLNTLIHHNEAVLHLRFS---NGLMVTCSKDRS 328
Query: 567 VRIWDYTQDACIN---ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDT 623
+ +WD I +L GH A V + ++ + ++S S D TIKVW T V T
Sbjct: 329 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY---IVSASGDRTIKVWSTSTCEFVRT 385
Query: 624 VYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
+ H G+ C R + S S D+T+RLW +
Sbjct: 386 LNGHKR---GIACLQYRDRLVVSGSSDNTIRLWDI 417
Score = 65.5 bits (158), Expect = 3e-10
Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 6/103 (5%)
Query: 558 LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRE 617
+ SG D +++IWD T C+ +L GHT V L ++ + +++GS D T++VWD
Sbjct: 240 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERV---IVTGSSDSTVRVWDVNT 296
Query: 618 GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
G ++T+ H V L M +CS+D ++ +W + +
Sbjct: 297 GEVLNTLIHHNEAVLHLRFSNG---LMVTCSKDRSIAVWDMAS 336
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/236 (24%), Positives = 96/236 (40%), Gaps = 49/236 (20%)
Query: 339 GHAVCCFLDGGVGLYDMGAKKWDFLRDL--GHVETIFDCKFKPDDPNLLATASFDGTIKV 396
G V C D + ++DM + LR + GH + F D + +AS D TIKV
Sbjct: 318 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKV 374
Query: 397 WDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGT 456
W +T V T G++ I L + + G+S N +W+++ G ++ H
Sbjct: 375 WSTSTCEFVRTLNGHKRGIACLQYRD---RLVVSGSSDNTIRLWDIECGACLRVLEGH-E 430
Query: 457 NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATG 516
+ CI + D+KRI + + DG I+ D + + PA +T
Sbjct: 431 ELVRCIRF---DNKRIVSGAYDG--KIKVWDLQAALDPRAPA---------------STL 470
Query: 517 CEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDY 572
C L+ H+ +VF +++ + + S S D T+ IWD+
Sbjct: 471 C-----------------LRTLVEHSGRVFRLQFDEFQ---IISSSHDDTILIWDF 506
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 87.4 bits (215), Expect = 8e-17
Identities = 77/278 (27%), Positives = 131/278 (47%), Gaps = 30/278 (10%)
Query: 361 DFLRDL-GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLS 419
DF R L GH +++ D F LLA+ S D TIK+WD + T G++ + S++
Sbjct: 141 DFERTLKGHTDSVQDISFDHSG-KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Query: 420 WAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDG 479
P G + ++ + +W VQ G ++ F H + ++D IA+CS+D
Sbjct: 200 IMPNGDHIVSASRDKT-IKMWEVQTGYCVKTFTGH--REWVRMVRPNQDGTLIASCSNDQ 256
Query: 480 FC---IIRTIDGKV-LHKYKH--------PAAVF-------GCDWSQNNKD--MIATGCE 518
++ T + K L +++H P + + G + ++ K + +G
Sbjct: 257 TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSR 316
Query: 519 DTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACI 578
D ++++ V+T L GH V V + + IL S +DD T+R+WDY C+
Sbjct: 317 DKTIKMWDVSTG--MCLMTLVGHDNWVRGVLFHSGGKFIL-SCADDKTLRVWDYKNKRCM 373
Query: 579 NILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTR 616
LN H V L ++ PY +++GS D T+KVW+ R
Sbjct: 374 KTLNAHEHFVTSLDFHKTAPY-VVTGSVDQTVKVWECR 410
Score = 81.6 bits (200), Expect = 4e-15
Identities = 70/247 (28%), Positives = 108/247 (43%), Gaps = 44/247 (17%)
Query: 439 IWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSD---------GFCIIRTIDGK 489
+W+ + G + H T+ + I++ H K +A+CS+D GF IRT+ G
Sbjct: 134 VWDYETGDFERTLKGH-TDSVQDISFDHS-GKLLASCSADMTIKLWDFQGFECIRTMHG- 190
Query: 490 VLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVK 549
H + + N D I + D ++++ V T +K F+GH V V+
Sbjct: 191 --HDHNVSSVAI-----MPNGDHIVSASRDKTIKMWEVQTG--YCVKTFTGHREWVRMVR 241
Query: 550 WSPLREG-ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPY--------- 599
P ++G ++ S S+D TVR+W C L H V + W E Y
Sbjct: 242 --PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGS 299
Query: 600 ----------LLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSR 649
L+SGS D TIK+WD G C+ T+ H V G+ H F + SC+
Sbjct: 300 ETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFIL-SCAD 358
Query: 650 DSTVRLW 656
D T+R+W
Sbjct: 359 DKTLRVW 365
Score = 78.6 bits (192), Expect = 4e-14
Identities = 82/311 (26%), Positives = 136/311 (43%), Gaps = 61/311 (19%)
Query: 383 NLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGG---LNCIAGGTSRNGAFI 439
+++ +AS D TIKVWD T T G+ + +S+ G +C A T + +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIK----L 176
Query: 440 WNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSD----------GFCIIRTIDGK 489
W+ Q + I+ + H N + D I + S D G+C ++T G
Sbjct: 177 WDFQGFECIRTMHGHDHNVSSVAIMPNGD--HIVSASRDKTIKMWEVQTGYC-VKTFTG- 232
Query: 490 VLHKYKHPAAVFGCDW---SQNNKD--MIATGCEDTNVRVYYVATSSDQPLKVFSGHTAK 544
H+ +W + N+D +IA+ D VRV+ VAT + H
Sbjct: 233 --HR----------EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK--AELREHEHV 278
Query: 545 VFHVKWSP------LREG-------------ILCSGSDDGTVRIWDYTQDACINILNGHT 585
V + W+P + E L SGS D T+++WD + C+ L GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 586 APVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMA 645
VRG+++++ ++L S + D T++VWD + C+ T+ H V L H + P+ +
Sbjct: 339 NWVRGVLFHSGGKFIL-SCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVT 397
Query: 646 SCSRDSTVRLW 656
S D TV++W
Sbjct: 398 G-SVDQTVKVW 407
Score = 68.6 bits (166), Expect = 4e-11
Identities = 39/120 (32%), Positives = 65/120 (54%), Gaps = 3/120 (2%)
Query: 539 SGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIP 598
SGH + V V + P+ ++ S S+D T+++WDY L GHT V+ + ++
Sbjct: 105 SGHRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFD-HSG 162
Query: 599 YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSL 658
LL S S D TIK+WD + C+ T++ H +V + P+ + S SRD T+++W +
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH-IVSASRDKTIKMWEV 221
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 87.0 bits (214), Expect = 1e-16
Identities = 77/309 (24%), Positives = 137/309 (44%), Gaps = 25/309 (8%)
Query: 361 DFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPG---NEGVIY- 416
+F +G I C F P+ +LATA + G K+W + ++T G N G I
Sbjct: 223 NFCSQIGDDRPISYCHFSPNS-KMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVF 281
Query: 417 ----SLSWAPGGLN---CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDS 469
++S P +N C A G+ + +W++ + + H T + + W H
Sbjct: 282 HPKSTVSLDPKDVNLASCAADGSVK----LWSLDSDEPVADIEGH-TVRVARVMW-HPSG 335
Query: 470 KRIATCSSDGFCIIRTIDGK--VLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYV 527
+ + T D + ++ + +LH+ H V+ + Q+ + TG D RV+ +
Sbjct: 336 RFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS-LAGTGGLDAFGRVWDL 394
Query: 528 ATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAP 587
T + + GH +++ + +SP I +GS D T ++WD Q C+ + H
Sbjct: 395 RTG--RCIMFLEGHLKEIYGINFSPNGYHI-ATGSGDNTCKVWDLRQRRCVYTIPAHQNL 451
Query: 588 VRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASC 647
V G+ + L++G++D T K+W + + T+ H V GL S +A+C
Sbjct: 452 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDI-SSDGQLIATC 510
Query: 648 SRDSTVRLW 656
S D T +LW
Sbjct: 511 SYDRTFKLW 519
Score = 38.9 bits (89), Expect = 0.032
Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 7/66 (10%)
Query: 600 LLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPS-------RPFTMASCSRDST 652
+L + W K+W + + T+ H +V + HP + +ASC+ D +
Sbjct: 245 MLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGS 304
Query: 653 VRLWSL 658
V+LWSL
Sbjct: 305 VKLWSL 310
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 86.3 bits (212), Expect = 2e-16
Identities = 70/293 (23%), Positives = 123/293 (41%), Gaps = 50/293 (17%)
Query: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
GH I D + D NLL +AS D T+K+WD+++ + T G+ ++ ++ P N
Sbjct: 85 GHKLGISDVAWSSDS-NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS-N 142
Query: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 486
I G+ IW+V+ GK ++ H ++ + + ++ +D I + S DG C I
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAH-SDPVSAVHFN-RDGSLIVSSSYDGLCRI--- 197
Query: 487 DGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVF 546
W + + T +D N V +V
Sbjct: 198 ------------------WDTASGQCLKTLIDDDNPPVSFV------------------- 220
Query: 547 HVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIP--YLLISG 604
K+SP + IL + D+ T+++WDY++ C+ GH + N + ++SG
Sbjct: 221 --KFSPNGKYILAATLDN-TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277
Query: 605 SWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP-FTMASCSRDSTVRLW 656
S D + +W+ + V + H V CHP+ A+ D T++LW
Sbjct: 278 SEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 80.9 bits (198), Expect = 7e-15
Identities = 73/259 (28%), Positives = 126/259 (48%), Gaps = 15/259 (5%)
Query: 406 YTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWS 465
+T G+ + S+ ++P G +A ++ IW GK + + H GI +AWS
Sbjct: 39 FTLAGHTKAVSSVKFSPNG-EWLASSSADKLIKIWGAYDGKFEKTISGHKL-GISDVAWS 96
Query: 466 HKDSKRIATCSSDGFCIIRTID-GKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVR 523
DS + + S D I + GK L K H VF C+++ + ++I +G D +VR
Sbjct: 97 -SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVR 154
Query: 524 VYYVATSSDQPLKVFSGHTAKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQDACIN-IL 581
++ V T + LK H+ V V ++ R+G ++ S S DG RIWD C+ ++
Sbjct: 155 IWDVKTG--KCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASGQCLKTLI 210
Query: 582 NGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPS-- 639
+ PV + ++ Y+L + + D T+K+WD +G C+ T H + Y + + S
Sbjct: 211 DDDNPPVSFVKFSPNGKYIL-AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVT 269
Query: 640 RPFTMASCSRDSTVRLWSL 658
+ S S D+ V +W+L
Sbjct: 270 GGKWIVSGSEDNLVYIWNL 288
Score = 42.4 bits (98), Expect = 0.003
Identities = 59/267 (22%), Positives = 106/267 (39%), Gaps = 22/267 (8%)
Query: 49 FKLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASL 108
+ L ++ H K ++++ + P N + AS S D L+ IW + K + K + +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 109 SWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFG 168
+W ++ +V+ S L IW +S + HS C F Q +V G
Sbjct: 94 AWSSDSNLLVS-ASDDKTLKIWDVS--SGKCLKTLKGHSNYVFCCNF---NPQSNLIVSG 147
Query: 169 HIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYG--IRL 226
D S+ I+ L S DPV+A+ + + D L+V+ Y R+
Sbjct: 148 SFDESVRIWDVKTGKCLKTLPAHS-------DPVSAVHF---NRDGSLIVSSSYDGLCRI 197
Query: 227 VDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKL 286
D+ S C+ T + V + + P+ G +I + L++W+ S+ +
Sbjct: 198 WDTASGQCLKTL-IDDDNPPVSFVKFSPN--GKYILAATLDNTLKLWDYSKGKCLKTYTG 254
Query: 287 KKTGFHCLHVLNSPPRKKFSVQSPTKN 313
K +C+ S K+ V N
Sbjct: 255 HKNEKYCIFANFSVTGGKWIVSGSEDN 281
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/43 (37%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 77 SGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVA 119
SGS DNLV IWN+ ++++ KL + S + C E+++A
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA-CHPTENIIA 317
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 86.3 bits (212), Expect = 2e-16
Identities = 70/293 (23%), Positives = 123/293 (41%), Gaps = 50/293 (17%)
Query: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
GH I D + D NLL +AS D T+K+WD+++ + T G+ ++ ++ P N
Sbjct: 85 GHKLGISDVAWSSDS-NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS-N 142
Query: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 486
I G+ IW+V+ GK ++ H ++ + + ++ +D I + S DG C I
Sbjct: 143 LIVSGSFDESVRIWDVKTGKCLKTLPAH-SDPVSAVHFN-RDGSLIVSSSYDGLCRI--- 197
Query: 487 DGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVF 546
W + + T +D N V +V
Sbjct: 198 ------------------WDTASGQCLKTLIDDDNPPVSFV------------------- 220
Query: 547 HVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIP--YLLISG 604
K+SP + IL + D+ T+++WDY++ C+ GH + N + ++SG
Sbjct: 221 --KFSPNGKYILAATLDN-TLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277
Query: 605 SWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP-FTMASCSRDSTVRLW 656
S D + +W+ + V + H V CHP+ A+ D T++LW
Sbjct: 278 SEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
Score = 80.9 bits (198), Expect = 7e-15
Identities = 73/259 (28%), Positives = 126/259 (48%), Gaps = 15/259 (5%)
Query: 406 YTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWS 465
+T G+ + S+ ++P G +A ++ IW GK + + H GI +AWS
Sbjct: 39 FTLAGHTKAVSSVKFSPNG-EWLASSSADKLIKIWGAYDGKFEKTISGHKL-GISDVAWS 96
Query: 466 HKDSKRIATCSSDGFCIIRTID-GKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVR 523
DS + + S D I + GK L K H VF C+++ + ++I +G D +VR
Sbjct: 97 -SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVR 154
Query: 524 VYYVATSSDQPLKVFSGHTAKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQDACIN-IL 581
++ V T + LK H+ V V ++ R+G ++ S S DG RIWD C+ ++
Sbjct: 155 IWDVKTG--KCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASGQCLKTLI 210
Query: 582 NGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPS-- 639
+ PV + ++ Y+L + + D T+K+WD +G C+ T H + Y + + S
Sbjct: 211 DDDNPPVSFVKFSPNGKYIL-AATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVT 269
Query: 640 RPFTMASCSRDSTVRLWSL 658
+ S S D+ V +W+L
Sbjct: 270 GGKWIVSGSEDNLVYIWNL 288
Score = 42.4 bits (98), Expect = 0.003
Identities = 59/267 (22%), Positives = 106/267 (39%), Gaps = 22/267 (8%)
Query: 49 FKLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASL 108
+ L ++ H K ++++ + P N + AS S D L+ IW + K + K + +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 109 SWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFG 168
+W ++ +V+ S L IW +S + HS C F Q +V G
Sbjct: 94 AWSSDSNLLVS-ASDDKTLKIWDVS--SGKCLKTLKGHSNYVFCCNF---NPQSNLIVSG 147
Query: 169 HIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYG--IRL 226
D S+ I+ L S DPV+A+ + + D L+V+ Y R+
Sbjct: 148 SFDESVRIWDVKTGKCLKTLPAHS-------DPVSAVHF---NRDGSLIVSSSYDGLCRI 197
Query: 227 VDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKL 286
D+ S C+ T + V + + P+ G +I + L++W+ S+ +
Sbjct: 198 WDTASGQCLKTL-IDDDNPPVSFVKFSPN--GKYILAATLDNTLKLWDYSKGKCLKTYTG 254
Query: 287 KKTGFHCLHVLNSPPRKKFSVQSPTKN 313
K +C+ S K+ V N
Sbjct: 255 HKNEKYCIFANFSVTGGKWIVSGSEDN 281
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/43 (37%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Query: 77 SGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVA 119
SGS DNLV IWN+ ++++ KL + S + C E+++A
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA-CHPTENIIA 317
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 84.0 bits (206), Expect = 9e-16
Identities = 75/300 (25%), Positives = 127/300 (42%), Gaps = 20/300 (6%)
Query: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGL 425
+GH E + KF P+ LA++S D I +W T G+ I ++W+
Sbjct: 38 VGHTEAVSSVKFSPNG-EWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 426 NCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRT 485
++ + +W+V+ GK ++ H +N +FC ++ + I+ + I
Sbjct: 97 RLVSASDDKT-LKLWDVRSGKCLKTLKGH-SNYVFCCNFNPPSNLIISGSFDETVKIWEV 154
Query: 486 IDGKVL-----HKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVF-S 539
GK L H A F C S +I +G D R++ A S Q LK
Sbjct: 155 KTGKCLKTLSAHSDPVSAVHFNCSGS-----LIVSGSYDGLCRIWDAA--SGQCLKTLVD 207
Query: 540 GHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIP- 598
V VK+SP + IL + + D T+++WDY++ C+ GH + N +
Sbjct: 208 DDNPPVSFVKFSPNGKYIL-TATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTG 266
Query: 599 -YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRP-FTMASCSRDSTVRLW 656
++SGS D + +W+ + V + H V CHP+ A+ D T++LW
Sbjct: 267 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 79.0 bits (193), Expect = 3e-14
Identities = 72/257 (28%), Positives = 120/257 (46%), Gaps = 13/257 (5%)
Query: 407 TSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSH 466
T G+ + S+ ++P G +A ++ IW GK + H I +AWS
Sbjct: 36 TLVGHTEAVSSVKFSPNG-EWLASSSADRLIIIWGAYDGKYEKTLYGHNLE-ISDVAWS- 92
Query: 467 KDSKRIATCSSDGFCIIRTI-DGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRV 524
DS R+ + S D + + GK L K H VF C+++ + ++I +G D V++
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPS-NLIISGSFDETVKI 151
Query: 525 YYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINIL-NG 583
+ V T + LK S H+ V V ++ ++ SGS DG RIWD C+ L +
Sbjct: 152 WEVKTG--KCLKTLSAHSDPVSAVHFN-CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD 208
Query: 584 HTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPS--RP 641
PV + ++ Y+L + + D T+K+WD G C+ T H + Y + + S
Sbjct: 209 DNPPVSFVKFSPNGKYIL-TATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGG 267
Query: 642 FTMASCSRDSTVRLWSL 658
+ S S D+ V +W+L
Sbjct: 268 KWIVSGSEDNLVYIWNL 284
Score = 37.0 bits (84), Expect = 0.12
Identities = 73/356 (20%), Positives = 138/356 (38%), Gaps = 61/356 (17%)
Query: 49 FKLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASL 108
+ L + H + ++++ + P N + AS S D L+IIW + K L + +
Sbjct: 31 YALKCTLVGHTEAVSSVKFSP-NGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDV 89
Query: 109 SWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFG 168
+W ++ +V+ S L +W + + HS C F ++ G
Sbjct: 90 AWSSDSSRLVS-ASDDKTLKLWDVR--SGKCLKTLKGHSNYVFCCNF---NPPSNLIISG 143
Query: 169 HIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGI-RLV 227
D ++ I+ L S DPV+A+ ++ + L+V + G+ R+
Sbjct: 144 SFDETVKIWEVKTGKCLKTLSAHS-------DPVSAVHFN--CSGSLIVSGSYDGLCRIW 194
Query: 228 DSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLK 287
D+ S C+ T + V + + P+ G +I + L++W+ SR +
Sbjct: 195 DAASGQCLKTL-VDDDNPPVSFVKFSPN--GKYILTATLDNTLKLWDYSRGRCLKTYTGH 251
Query: 288 KTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLD 347
K +C+ F+ S T + S SE D
Sbjct: 252 KNEKYCI----------FANFSVTGGKWIVSGSE-------------------------D 276
Query: 348 GGVGLYDMGAKKWDFLRDL-GHVETIFDCKFKPDDPNLLATASF--DGTIKVWDIN 400
V ++++ K + ++ L GH + + P + NL+A+A+ D TIK+W N
Sbjct: 277 NLVYIWNLQTK--EIVQKLQGHTDVVISAACHPTE-NLIASAALENDKTIKLWMSN 329
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 82.0 bits (201), Expect = 3e-15
Identities = 63/216 (29%), Positives = 101/216 (46%), Gaps = 14/216 (6%)
Query: 468 DSKRIATCSSD---GFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV 524
DS + +CS D + + + VL++ H V+ D S + A+G D R+
Sbjct: 353 DSSGLLSCSEDMSIRYWDLGSFTNTVLYQ-GHAYPVWDLDISPYSL-YFASGSHDRTARL 410
Query: 525 YYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGH 584
+ + PL++++GH A V VK+ P L +GS D TVR+W Q + + GH
Sbjct: 411 W--SFDRTYPLRIYAGHLADVDCVKFHP-NSNYLATGSTDKTVRLWSAQQGNSVRLFTGH 467
Query: 585 TAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTM 644
PV L ++ YL +G D +K+WD GT + H ++ LT P +
Sbjct: 468 RGPVLSLAFSPNGKYLASAGE-DQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGL-I 525
Query: 645 ASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIG 680
AS S D++VR+W + + AD S E++G
Sbjct: 526 ASASMDNSVRVWD----IRNTYCSAPADGSSSELVG 557
Score = 65.1 bits (157), Expect = 4e-10
Identities = 61/254 (24%), Positives = 115/254 (45%), Gaps = 12/254 (4%)
Query: 340 HAVCCFLDGGVGLYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDI 399
H C L+ D + LR GH ++ +F D LL+ S D +I+ WD+
Sbjct: 315 HLACDILEEEDDEDDNAGTEMKILR--GHCGPVYSTRFLADSSGLLS-CSEDMSIRYWDL 371
Query: 400 NTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGI 459
+ T G+ ++ L +P L +G R A +W+ + ++ + H + +
Sbjct: 372 GSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRT-ARLWSFDRTYPLRIYAGHLAD-V 429
Query: 460 FCIAWSHKDSKRIATCSSDGFCIIRTID-GKVLHKYK-HPAAVFGCDWSQNNKDMIATGC 517
C+ + H +S +AT S+D + + G + + H V +S N K + + G
Sbjct: 430 DCVKF-HPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAG- 487
Query: 518 EDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC 577
ED ++++ +A+ + K GHT + + +SP G++ S S D +VR+WD C
Sbjct: 488 EDQRLKLWDLASGT--LYKELRGHTDNITSLTFSP-DSGLIASASMDNSVRVWDIRNTYC 544
Query: 578 INILNGHTAPVRGL 591
+G ++ + G+
Sbjct: 545 SAPADGSSSELVGV 558
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 81.3 bits (199), Expect = 6e-15
Identities = 80/340 (23%), Positives = 145/340 (42%), Gaps = 52/340 (15%)
Query: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
GH E + F P LA+ S D T++ WD++T T +T G+ + S+SW+P G
Sbjct: 112 GHSEAVISVAFSPTG-KYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRK 170
Query: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAW----SHKDSKRIATCSSDGFC- 481
+A G +W+ GK + R + I ++W ++ + + +A+ S DG
Sbjct: 171 -LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 482 IIRTIDGKVLHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVY--------------- 525
I T G+ H +V W + ++ + +D ++V+
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG--LLYSASQDRTIKVWRAHDGVLCRTLQGHG 287
Query: 526 ----YVATSSDQPLKVFSGHTAKV------FHVKWSPLREGI--------------LCSG 561
+A S+D L+ + A+ L+E L SG
Sbjct: 288 HWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSG 347
Query: 562 SDDGTVRIWDYTQD-ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTC 620
SDD T+ +W +D + + GH A + ++++ + ++ S S+D +IK+WD R G
Sbjct: 348 SDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD-SRIVASASFDKSIKLWDGRTGKY 406
Query: 621 VDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTA 660
+ ++ H A VY + + S S DST+++W + A
Sbjct: 407 LASLRGHVAAVYQIAWSADSRL-LVSGSSDSTLKVWDVKA 445
Score = 78.2 bits (191), Expect = 5e-14
Identities = 87/367 (23%), Positives = 141/367 (38%), Gaps = 66/367 (17%)
Query: 345 FLDGGVGLYDMGAKKWDFLRDL------GHVETIFDCKFKPDDPNLLATASFDGTIKVWD 398
+L G G D + WD + GH + + PD L A+ +G I +WD
Sbjct: 128 YLASGSG--DTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKL-ASGCKNGQILLWD 184
Query: 399 INTLTAV-YTSPGNEGVIYSLSWAPGGLN----CIAGGTSRNGAFIWNVQKGKIIQRFNE 453
+T V T G+ I LSW P N +A + IW+ G+ +
Sbjct: 185 PSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTG 244
Query: 454 HGTNGIFCIAW-------SHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDW- 505
H T + C+ W S + I + + RT+ G H + D+
Sbjct: 245 H-TQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQG---HGHWVNTMALSTDYA 300
Query: 506 -----------SQNNKDM-------------------------IATGCEDTNVRVYYVAT 529
S N +D+ + +G +D + ++ A
Sbjct: 301 LRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAE 360
Query: 530 SSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVR 589
+PL +GH A + V +SP I+ S S D ++++WD + L GH A V
Sbjct: 361 DK-KPLTRMTGHQALINQVLFSP-DSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVY 418
Query: 590 GLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSR 649
+ W+ + LL+SGS D T+KVWD + + H +VY + P +AS +
Sbjct: 419 QIAWSAD-SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ-RVASGGK 476
Query: 650 DSTVRLW 656
D +R+W
Sbjct: 477 DKCLRIW 483
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 79.7 bits (195), Expect = 2e-14
Identities = 61/248 (24%), Positives = 106/248 (42%), Gaps = 49/248 (19%)
Query: 367 GHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
GH ++ F PD N L ++S DGT+++W + T T + G+ ++ ++P G
Sbjct: 541 GHSGPVYGASFSPDR-NYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYY 599
Query: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 486
++GG R A +W ++D + +R
Sbjct: 600 FVSGGHDRV-ARLW-----------------------------------ATDHYQPLRIF 623
Query: 487 DGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVF 546
G + A C N + +ATG D VR++ V + +++F+GH +
Sbjct: 624 AGHL--------ADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNC--VRIFTGHKGPIH 673
Query: 547 HVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSW 606
+ +SP L +G+ DG V +WD + L GHT V L ++ + +L SGS
Sbjct: 674 SLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRD-GEILASGSM 731
Query: 607 DYTIKVWD 614
D T+++WD
Sbjct: 732 DNTVRLWD 739
Score = 75.5 bits (184), Expect = 3e-13
Identities = 73/289 (25%), Positives = 119/289 (41%), Gaps = 42/289 (14%)
Query: 380 DDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFI 439
DD +L+A D T++VW + P L + + + +
Sbjct: 480 DDSSLIAGGFADSTVRVWSVT---------------------PKKLRSVKQASDLS---L 515
Query: 440 WNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSD-GFCIIRTIDGKV-------- 490
+ + +++R + T I + H A+ S D + + + DG V
Sbjct: 516 IDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTF 575
Query: 491 --LHKYK-HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFH 547
L YK H V+ +S ++ G D R++ AT QPL++F+GH A V
Sbjct: 576 TCLVGYKGHNYPVWDTQFSPYGYYFVSGG-HDRVARLW--ATDHYQPLRIFAGHLADVNC 632
Query: 548 VKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD 607
++ P + +GS D TVR+WD C+ I GH P+ L ++ + L +G+ D
Sbjct: 633 TRFHP-NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRF-LATGATD 690
Query: 608 YTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
+ +WD G V + H V L +AS S D+TVRLW
Sbjct: 691 GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEI-LASGSMDNTVRLW 738
Score = 70.1 bits (170), Expect = 1e-11
Identities = 48/144 (33%), Positives = 71/144 (49%), Gaps = 11/144 (7%)
Query: 518 EDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDAC 577
+D R+ T+S+ LK+ GH+ V+ +SP R +L S S+DGTVR+W C
Sbjct: 521 DDVLERIMDEKTASE--LKILYGHSGPVYGASFSPDRNYLL-SSSEDGTVRLWSLQTFTC 577
Query: 578 INILNGHTAPVRGLMWNTEIP---YLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGL 634
+ GH PV W+T+ Y +SG D ++W T + H ADV
Sbjct: 578 LVGYKGHNYPV----WDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCT 633
Query: 635 TCHPSRPFTMASCSRDSTVRLWSL 658
HP+ + +A+ S D TVRLW +
Sbjct: 634 RFHPNSNY-VATGSADRTVRLWDV 656
Score = 52.8 bits (125), Expect = 2e-06
Identities = 39/140 (27%), Positives = 73/140 (52%), Gaps = 13/140 (9%)
Query: 345 FLDGGVGLYDMGAKKW--DFLRDL----GHVETIFDCKFKPDDPNLLATASFDGTIKVWD 398
F+ GG +D A+ W D + L GH+ + +F P+ N +AT S D T+++WD
Sbjct: 600 FVSGG---HDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNS-NYVATGSADRTVRLWD 655
Query: 399 INTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNG 458
+ V G++G I+SL+++P G +A G + +W++ G ++ H T+
Sbjct: 656 VLNGNCVRIFTGHKGPIHSLTFSPNG-RFLATGATDGRVLLWDIGHGLMVGELKGH-TDT 713
Query: 459 IFCIAWSHKDSKRIATCSSD 478
+ + +S +D + +A+ S D
Sbjct: 714 VCSLRFS-RDGEILASGSMD 732
Score = 50.4 bits (119), Expect = 1e-05
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 19/179 (10%)
Query: 508 NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTV 567
++ +IA G D+ VRV+ V + +K S + ++ SDD
Sbjct: 480 DDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLS--------------LIDKESDDVLE 525
Query: 568 RIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDH 627
RI D + + IL GH+ PV G ++ + YLL S S D T+++W + TC+ H
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLL-SSSEDGTVRLWSLQTFTCLVGYKGH 584
Query: 628 GADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQI--NILADRSWEEIIGNTDY 684
V+ P + S D RLW+ T P++I LAD + N++Y
Sbjct: 585 NYPVWDTQFSP-YGYYFVSGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRFHPNSNY 641
Score = 30.8 bits (68), Expect = 8.8
Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 54 IMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWN 113
I + HK I ++++ P N A+G+TD V++W++ ++ +L SL + +
Sbjct: 664 IFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRD 722
Query: 114 AEDVVAFVSHRGPLFIW 130
E ++A S + +W
Sbjct: 723 GE-ILASGSMDNTVRLW 738
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 79.3 bits (194), Expect = 2e-14
Identities = 77/287 (26%), Positives = 129/287 (44%), Gaps = 25/287 (8%)
Query: 383 NLLATASFDGTIKVW-----DINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGA 437
N+LA A D ++ +W DI L + PG I S++W G N +A GTS
Sbjct: 196 NVLAVA-LDNSVYLWSASSGDILQLLQM-EQPGE--YISSVAWIKEG-NYLAVGTSSAEV 250
Query: 438 FIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCI---IRTIDGKVLHKY 494
+W+VQ+ K ++ H + ++W+ S +++ S G +R + V
Sbjct: 251 QLWDVQQQKRLRNMTSHSAR-VGSLSWN---SYILSSGSRSGHIHHHDVRVAEHHVATLS 306
Query: 495 KHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQ--PLKVFSGHTAKVFHVKWSP 552
H V G W+ + + + A+G D V V+ A PL+ F+ H V V W P
Sbjct: 307 GHSQEVCGLRWAPDGRHL-ASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCP 365
Query: 553 LREGILCSG--SDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLIS-GSWDYT 609
+ +L +G + D +RIW+ AC++ ++ H + V ++W+ L+ G
Sbjct: 366 WQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAH-SQVCSILWSPHYKELISGHGFAQNQ 424
Query: 610 IKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
+ +W V + H + V LT P T+AS + D T+RLW
Sbjct: 425 LVIWKYPTMAKVAELKGHTSRVLSLTMSPDGA-TVASAAADETLRLW 470
Score = 48.1 bits (113), Expect = 5e-05
Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 11/155 (7%)
Query: 504 DWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREG-ILCSGS 562
DWS N ++A +++ VY + SS L++ + + ++EG L G+
Sbjct: 191 DWSSGN--VLAVALDNS---VYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGT 245
Query: 563 DDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGT-CV 621
V++WD Q + + H+A V L WN+ Y+L SGS I D R V
Sbjct: 246 SSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS---YILSSGSRSGHIHHHDVRVAEHHV 302
Query: 622 DTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
T+ H +V GL P +AS D+ V +W
Sbjct: 303 ATLSGHSQEVCGLRWAPDGRH-LASGGNDNLVNVW 336
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/164 (26%), Positives = 69/164 (42%), Gaps = 24/164 (14%)
Query: 13 GCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNP 72
G WN + + SG R + I+ D R E + A +S H + + + W P
Sbjct: 272 GSLSWNSYILS-SGSRSGH-------IHHHDVRVAEHHV-ATLSGHSQEVCGLRWAPDGR 322
Query: 73 DLFASGSTDNLVIIWNVAEQK----VIAKLDSTKGIPASLSWCWNAEDVVAF---VSHRG 125
L ASG DNLV +W A + + +G +++WC +V+A S R
Sbjct: 323 HL-ASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDR- 380
Query: 126 PLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGH 169
+ IW + + DAH S +C W H K +++ GH
Sbjct: 381 HIRIWNVC--SGACLSAVDAH---SQVCSILWSPHYK-ELISGH 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,634,848
Number of Sequences: 37866
Number of extensions: 2492141
Number of successful extensions: 8817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 153
Number of HSP's that attempted gapping in prelim test: 5442
Number of HSP's gapped (non-prelim): 1941
length of query: 1298
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1184
effective length of database: 13,930,794
effective search space: 16494060096
effective search space used: 16494060096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.