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Search of human proteins with 54607124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54607124 RNA binding motif protein 15B [Homo sapiens]
(890 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 1799 0.0
gi|47933339 RNA binding motif protein 15 [Homo sapiens] 613 e-175
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 113 7e-25
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 62 2e-09
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 58 3e-08
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 58 3e-08
gi|109240550 paraspeckle protein 1 [Homo sapiens] 58 4e-08
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 57 8e-08
gi|49087132 sal-like 2 [Homo sapiens] 57 1e-07
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 56 1e-07
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 56 2e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 55 2e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 55 2e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 55 2e-07
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 54 5e-07
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 54 5e-07
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 54 5e-07
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 54 8e-07
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 54 8e-07
gi|52426743 cisplatin resistance-associated overexpressed protei... 54 8e-07
gi|19923485 cisplatin resistance-associated overexpressed protei... 54 8e-07
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 53 1e-06
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 52 2e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 52 2e-06
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 52 2e-06
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 52 2e-06
gi|148612890 serine-arginine repressor protein [Homo sapiens] 52 3e-06
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 52 3e-06
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 51 5e-06
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 1799 bits (4660), Expect = 0.0
Identities = 890/890 (100%), Positives = 890/890 (100%)
Query: 1 MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGS 60
MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGS
Sbjct: 1 MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGS 60
Query: 61 GSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPP 120
GSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPP
Sbjct: 61 GSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPP 120
Query: 121 PPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELG 180
PPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELG
Sbjct: 121 PPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELG 180
Query: 181 RVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPP 240
RVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPP
Sbjct: 181 RVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPP 240
Query: 241 PGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSR 300
PGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSR
Sbjct: 241 PGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSR 300
Query: 301 ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY 360
ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY
Sbjct: 301 ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY 360
Query: 361 GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRL 420
GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRL
Sbjct: 361 GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRL 420
Query: 421 WVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGG 480
WVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGG
Sbjct: 421 WVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGG 480
Query: 481 PDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSD 540
PDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSD
Sbjct: 481 PDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSD 540
Query: 541 RDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLS 600
RDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLS
Sbjct: 541 RDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLS 600
Query: 601 SDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGA 660
SDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGA
Sbjct: 601 SDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGA 660
Query: 661 EERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQL 720
EERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQL
Sbjct: 661 EERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQL 720
Query: 721 GWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVT 780
GWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVT
Sbjct: 721 GWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVT 780
Query: 781 RRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLP 840
RRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLP
Sbjct: 781 RRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLP 840
Query: 841 VGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA 890
VGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA
Sbjct: 841 VGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA 890
>gi|47933339 RNA binding motif protein 15 [Homo sapiens]
Length = 977
Score = 613 bits (1580), Expect = e-175
Identities = 414/932 (44%), Positives = 515/932 (55%), Gaps = 94/932 (10%)
Query: 14 RGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRD---G 70
RG S R ER + GG ++ +S G R S GG R+ G
Sbjct: 59 RGGEDSTSRG---ERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTG 115
Query: 71 RGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPG 130
G+ + + S S+ + +GGG + G G S S GA + PG
Sbjct: 116 GGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS-------------GAASSAPG 162
Query: 131 SSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELG----RVAYVN 186
A EYKTL IS L L E +ED LFH+FKRFG++S+++SH G RVA+VN
Sbjct: 163 GGDGA-EYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVN 221
Query: 187 FRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAP 246
FR P+DAR A+ HA R L+LYDRPLK+E VY+ SRR S S T PP
Sbjct: 222 FRRPEDARAAK-HARGR-LVLYDRPLKIEAVYV------SRRRSRSPLDKDTYPPSASVV 273
Query: 247 ADPLG---YLPLHGGYQYKQRSLSPV-AAPPLREPRARHAAAAFALDAAAAAAVGLSRER 302
+G + P GG QRSLSP AA R+ R + A L + ER
Sbjct: 274 GASVGGHRHPPGGGG---GQRSLSPGGAALGYRDYRLQQLALG-RLPPPPPPPLPRDLER 329
Query: 303 ALDY---------YGLYDDRGRPYGYPAVCEED-LMPEDDQRATRNLFIGNLDHSVSEVE 352
DY Y L G G E D + PEDDQRA R LF+GNLD +V+E +
Sbjct: 330 ERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESD 389
Query: 353 LRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYG 412
LRRAF+++G+I EV IKRP+RGQ Y FLKF+NLDM+HRAK+AMSG++I RNPIKIGYG
Sbjct: 390 LRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYG 449
Query: 413 KANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAK 472
KA PTTRLWVGGLGP LAALAREFDRFG+IRTID+ KGDS+AYIQYESLDAA AA
Sbjct: 450 KATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTH 509
Query: 473 MRGFPLGGPDRRLRVDFAKAEETRYPQQY-QPSPLPVHYELLTDGYTRHRNLDADLVRDR 531
MRGFPLGGPDRRLRVDFA E RY QQY QP PL HYEL+TD + RDR
Sbjct: 510 MRGFPLGGPDRRLRVDFADTEH-RYQQQYLQPLPL-THYELVTDAFGHRAPDPLRGARDR 567
Query: 532 TPPHLLYSDRDR-TFLEGDWTSPSKSSDRRN------SLEGYS-RSVRSRSGERWGAD-- 581
TPP LLY DRDR + + DW P R+ S+ Y R + W D
Sbjct: 568 TPP-LLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRD 626
Query: 582 -GDRGLPKPWEERRKRRSLSSDRGR-TTHSPYEERSRTKGSGQQSERGSDRTPERSRKEN 639
GDR LP ++ RKRR GR SP +R R + DR+PE S +
Sbjct: 627 RGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKR----HCAPSPDRSPELSSSRD 682
Query: 640 HSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAE--PKP 697
+ SS L + RG + + +R HRTT P
Sbjct: 683 RYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSP 742
Query: 698 LEEPKHE----------TKKLKNLSE-----------YAQTLQLGWNGLLVLKNSCFPTS 736
L++ + KLK+ S+ + L L W G+L+LKNS FP++
Sbjct: 743 LKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSN 802
Query: 737 MHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLA 796
MH+L+GD V SSLL + ++G K+ QLKI QRLRLDQPKLDEVTRRIK PNGYA+LLA
Sbjct: 803 MHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLA 862
Query: 797 TQATPSGLGTEGMPTVEPGLQ-RRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYA 855
+ + + +R LRNLVSYLKQKQAAGVISLPVGG+K ++ TG+L+A
Sbjct: 863 VPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHA 922
Query: 856 FPPCDFSQQYLQSALRTLGKLEEEHMVIVIVR 887
FPPC+FSQQ+L S + L K EE+++V++IVR
Sbjct: 923 FPPCEFSQQFLDSPAKALAKSEEDYLVMIIVR 954
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 113 bits (283), Expect = 7e-25
Identities = 111/420 (26%), Positives = 181/420 (43%), Gaps = 67/420 (15%)
Query: 325 EDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKF 384
++ + E +ATR LFIGNL+ + + +LR F+++G I ++ IK+ YAFL++
Sbjct: 426 DERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKV--NGVPQYAFLQY 483
Query: 385 QNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSI 444
++ +A M G +G N +K+G+GK+ PT +W+ GL N S L R F R+G +
Sbjct: 484 CDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFCRYGPV 543
Query: 445 RTI--DHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEET---RYPQ 499
+ D +KG A + Y ++ AQAA + +G +GG +++VDFA E +
Sbjct: 544 VKVVFDRLKG--MALVLYNEIEYAQAAVKETKGRKIGG--NKIKVDFANRESQLAFYHCM 599
Query: 500 QYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLL-------------YSDRDRTF- 545
+ + YE+L + R D +DRT + Y R R F
Sbjct: 600 EKSGQDIRDFYEMLAE-RREERRASYDYNQDRTYYESVRTPGTYPEDSRRDYPARGREFY 658
Query: 546 -----LEGD------WTSPSKSSDRRN-----SLEGYSRSVRSRSGERWGADGDRGLPKP 589
+GD + P + D RN + YS R R ER + DR +
Sbjct: 659 SEWETYQGDYYESRYYDDPREYRDYRNDPYEQDIREYSYRQRERERERERFESDR--DRD 716
Query: 590 WEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESS 649
E R RS S R SP S+ ++R P S + +S + S
Sbjct: 717 HERRPIERSQSPVHLRRPQSPGASPSQ-----------AERLPSDSERRLYSRSSDRSGS 765
Query: 650 SNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLK 709
+SLS R +E D S ++ +E+ + +P+ +E + +K K
Sbjct: 766 CSSLSPPR------------YEKLDKSRLERYTKNEKTDKERTFDPERVERERRLIRKEK 813
Score = 73.6 bits (179), Expect = 8e-13
Identities = 56/200 (28%), Positives = 97/200 (48%), Gaps = 20/200 (10%)
Query: 691 TEAEPKPLEE--PKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVIS 748
TE +P P ++ P +++ ++ + + + W GLL LKN +H + G+ +
Sbjct: 3476 TEFQPAPKQDSSPHLTSQRPVDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAH 3535
Query: 749 SLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEG 808
L G L+IAQR+RL+ +L+ V RR+ Y +LL A P G E
Sbjct: 3536 RSLPLSEGG---PPLRIAQRMRLEATQLEGVARRMT--VETDYCLLL---ALPCGRDQED 3587
Query: 809 MPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQ- 867
+ + L+ ++YL+ KQAAG+I++P GS +L FPPC+FS+ +L
Sbjct: 3588 VVSQTESLKAA----FITYLQAKQAAGIINVPNPGS--NQPAYVLQIFPPCEFSESHLSR 3641
Query: 868 ---SALRTLGKLEEEHMVIV 884
L ++ + M+++
Sbjct: 3642 LAPDLLASISNISPHLMIVI 3661
Score = 72.4 bits (176), Expect = 2e-12
Identities = 94/344 (27%), Positives = 139/344 (40%), Gaps = 50/344 (14%)
Query: 334 RATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRA 393
R TR+L++GNL +V E ++ F++YG +E V I +GG AF+ F ++ A +A
Sbjct: 3 RETRHLWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGSEGGVAAFVDFVDIKSAQKA 62
Query: 394 KVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGD 453
+++ +G ++ Y + T GL S+A+ +RE F G
Sbjct: 63 HNSVN--KMGDRDLRTDYNEPG-TIPSAARGLDDTVSIASRSREVSGFRG-------GGG 112
Query: 454 SFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELL 513
AY SL A + G +RRL D A R Y+ S H+E
Sbjct: 113 GPAYGPPPSLHARE-----------GRYERRL--DGASDNRER---AYEHSAYG-HHERG 155
Query: 514 TDGYTRHRNLDADLVRD---RTPPH-LLYSDRDRTFLEGDWTSPSKSSDRRNSL------ 563
T G+ R R+ D D RD RT H L Y+ R R+ D P R
Sbjct: 156 TGGFDRTRHYDQDYYRDPRERTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVV 215
Query: 564 ------EGYSRSVRSRSGERWGADGDRGLPKPWEERRKR-RSLSSDRGRTTHSPYEERSR 616
+ +R VR R ER P + R + + L+S R T SP SR
Sbjct: 216 HRDIYRDDITREVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSR 275
Query: 617 TKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGA 660
++ S SD S + SS+ + SS +S + S A
Sbjct: 276 SRSS------SSDSISSSSSTSSDSSDSSSSSSDDSPARSVQSA 313
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)
Query: 80 ASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYK 139
+ + R + S +G G R +S D +S S + PA SAA P
Sbjct: 260 SQASRPTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSDDSPARSVQSAAVPAPT 319
Query: 140 TLLISSLSPALPAEH----------------LEDRLFHQFKRFGEISLRLSHTPELGRVA 183
+ L+SSL P + L+D LFH+FK+FG+++ H R
Sbjct: 320 SQLLSSLEKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKFGKVTSVQIHGTSEERYG 379
Query: 184 YVNFRHPQDAREA 196
V FR +D +A
Sbjct: 380 LVFFRQQEDQEKA 392
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 62.4 bits (150), Expect = 2e-09
Identities = 44/134 (32%), Positives = 58/134 (43%), Gaps = 15/134 (11%)
Query: 9 SSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSG---GG 65
S+ G S SS E + GG+ + + SGG + + GSG G GG
Sbjct: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
Query: 66 GHRDGRGTGDAN-HRASSGRSSGSGAGGG-GRGGKASGDPGAS----------GMSPRAS 113
GH G G G + H + G++SG G G G G+G G+ G S S +
Sbjct: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQ 626
Query: 114 PLPPPPPPPGAEPA 127
PPPPPPP PA
Sbjct: 627 MPPPPPPPPPPPPA 640
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 9 SSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHR 68
S SG GS + + + +E + G SGG P+ + G+G G GG +
Sbjct: 458 SEVSGSGSGNFGEEGNPQGKEDQEG--------SGGDYMPM----NNWGSGNGRGSGGGQ 505
Query: 69 DGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASG 107
G G ++H SSG + SG G G RGG+ S G+ G
Sbjct: 506 GSNGQGSSSH--SSGGNQCSGEGQGSRGGQGSNGQGSGG 542
Score = 36.2 bits (82), Expect = 0.14
Identities = 32/104 (30%), Positives = 39/104 (37%), Gaps = 9/104 (8%)
Query: 11 PSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDG 70
P GR S + P R R H A AR + GSGSG G +G
Sbjct: 417 PRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNG---ARLSSEVSGSGSGNFGE-EG 472
Query: 71 RGTGDANHRASSG-----RSSGSGAGGGGRGGKASGDPGASGMS 109
G + S G + GSG G G GG+ S G+S S
Sbjct: 473 NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS 516
Score = 30.4 bits (67), Expect = 7.6
Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 26/129 (20%)
Query: 6 ERDSSPSGRGSSSSAKRPRERERE--------AEAGGRRAAHKASG----GAKHPVP-AR 52
ERD SPS + +SA P + A A G AA A+G A+ P A
Sbjct: 1109 ERDLSPSSAPAVASAAEPTLALSQVVAAASALAAAPGIGAAAAAAGFDSASARWFQPVAN 1168
Query: 53 ARDKP--RGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSP 110
A D RG+ GG G H S+ + G GG A+ +P P
Sbjct: 1169 AADAEAVRGAQDVAGGSNPGA------HNPSANLARGDNQAGGAAAAAAAPEP-----PP 1217
Query: 111 RASPLPPPP 119
R+ +P PP
Sbjct: 1218 RSRRVPRPP 1226
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 58.2 bits (139), Expect = 3e-08
Identities = 69/276 (25%), Positives = 111/276 (40%), Gaps = 35/276 (12%)
Query: 416 PTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGD-------SFAYIQYESLDAAQA 468
P T L+V + +T L REF R+G I + +V D FAY+Q+E + A+
Sbjct: 8 PNTSLFVRNVADDTRSEDLRREFGRYGPIVDV-YVPLDFYTRRPRGFAYVQFEDVRDAED 66
Query: 469 ACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLV 528
A + + G R++ + FA+ + Q V+ D Y R+R
Sbjct: 67 ALHNLDRKWICG--RQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYR------- 117
Query: 529 RDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPK 588
R R+ + R R+F D+ S R + G R RS S D DR +
Sbjct: 118 RSRSRSYERRRSRSRSF---DYNYRRSYSPRNSRPTGRPRRSRSHS------DNDRFKHR 168
Query: 589 PWEERRKRRSLSSDRGRTTHSPYEE---RSRTKGSGQQSERGSDRTPERSRKEN---HSS 642
R RS S+ R R+ P +E +SR++ + RG+ +T ++ ++ +
Sbjct: 169 ---NRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK 225
Query: 643 EGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHG 678
E K+ S S SR + R + S G
Sbjct: 226 ESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSG 261
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 58.2 bits (139), Expect = 3e-08
Identities = 81/370 (21%), Positives = 125/370 (33%), Gaps = 88/370 (23%)
Query: 329 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEV-VIKRPARGQGGAYAFLKFQNL 387
P A + LF+ +++ +E +LRR FE YG I+ + ++ G+ YAF+++++
Sbjct: 95 PNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHE 154
Query: 388 DMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLW-----VGGLGPNTSLAALAREFDRFG 442
H A G+ I + + + T + W GGLG
Sbjct: 155 RDMHSAYKHADGKKIDGRRVLVDVERGR-TVKGWRPRRLGGGLG---------------- 197
Query: 443 SIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQ 502
G GG D +R + + +RY ++
Sbjct: 198 --------------------------------GTRRGGADVNIR-HSGRDDTSRYDERPG 224
Query: 503 PSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNS 562
PSPLP HR+ D D R+R +R R + S+S DRR
Sbjct: 225 PSPLP------------HRDRDRDRERER-------RERSRERDKERERRRSRSRDRRRR 265
Query: 563 LEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQ 622
+ R RS ER D DR +R++R S S +R R EE G
Sbjct: 266 SRSRDKEERRRSRER-SKDKDR-------DRKRRSSRSRERARRERERKEELRGGGGDMA 317
Query: 623 QSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKAR 682
+ D P+ +G R R H D + R
Sbjct: 318 EPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRE--RRRSHRSERERRRDRD---RDR 372
Query: 683 DSERNHRTTE 692
D +R H+ E
Sbjct: 373 DRDREHKRGE 382
Score = 31.6 bits (70), Expect = 3.4
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 8/69 (11%)
Query: 2 KRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSG 61
+R ++D R S S + RERER+ E G GG P+ A D P G
Sbjct: 279 ERSKDKDRDRKRRSSRSRERARRERERKEELRG--------GGGDMAEPSEAGDAPPDDG 330
Query: 62 SGGGGHRDG 70
G DG
Sbjct: 331 PPGELGPDG 339
Score = 31.2 bits (69), Expect = 4.5
Identities = 29/124 (23%), Positives = 40/124 (32%), Gaps = 22/124 (17%)
Query: 3 RQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHP-------------- 48
+ +RD S A+R RER+ E GG A + G P
Sbjct: 282 KDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPD 341
Query: 49 -VPARARDKPRGSGSGGGGHRDGRGTGDANH-------RASSGRSSGSGAGGGGRGGKAS 100
+ RD+ R R+ R D + R G G GG GG+ +
Sbjct: 342 GPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDN 401
Query: 101 GDPG 104
G G
Sbjct: 402 GLEG 405
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 57.8 bits (138), Expect = 4e-08
Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 9/157 (5%)
Query: 290 AAAAAAVGLSRERALDYYGLYDDR-GRPYGYPAVCEEDLMPEDDQRATR-NLFIGNLDHS 347
AAAA A+ L+ E A +D G+ + L P + R LF+GNL
Sbjct: 33 AAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPGEKTYTQRCRLFVGNLPTD 92
Query: 348 VSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPI 407
++E + +R FE+YG EV I R RG + F++ ++ +A AK + G ++ P+
Sbjct: 93 ITEEDFKRLFERYGEPSEVFINRD-RG----FGFIRLESRTLAEIAKAELDGTILKSRPL 147
Query: 408 KIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSI 444
+I + A L V L P S L + F +FG +
Sbjct: 148 RIRF--ATHGAALTVKNLSPVVSNELLEQAFSQFGPV 182
Score = 31.6 bits (70), Expect = 3.4
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 419 RLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPL 478
RL+VG L + + R F+R+G + + F +I+ ES A+ A A++ G L
Sbjct: 83 RLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTIL 142
Query: 479 GGPDRRLRVDFA 490
R LR+ FA
Sbjct: 143 --KSRPLRIRFA 152
Score = 30.0 bits (66), Expect = 10.0
Identities = 17/55 (30%), Positives = 28/55 (50%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRA 393
L + NL VS L +AF ++G +E+ V+ RG+ F++F A +A
Sbjct: 158 LTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKA 212
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 57.0 bits (136), Expect = 8e-08
Identities = 85/296 (28%), Positives = 112/296 (37%), Gaps = 51/296 (17%)
Query: 3 RQSERDSSPSG-------RGSSSSAKRP---RERER-EAEAGGRRAAHKASGGAKHPVPA 51
++ RD S SG R SS KR +E++R E+ GRR+ +SG + P +
Sbjct: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLS 266
Query: 52 RARDKPRGSGSGGGGHRD-GRGTGDANHRASSGRS----SGSGAGGGGRGGKASGDPGAS 106
R HRD GR TG + R+S RS GSG G R G + GA
Sbjct: 267 SHYSDSRSPSRLSPKHRDEGRKTG--SQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAH 324
Query: 107 GMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRF 166
G P ++ PP P + ++AAAP PA E R +
Sbjct: 325 GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPT---------PPARGKESPSPRSAPSSQGR 375
Query: 167 GEISLRLSHTPELGRVAYV---NFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGG 223
G GR A R + R +R A A + RP P RG
Sbjct: 376 G------------GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPP---RGSS 420
Query: 224 GS-SRRSSSSSAAASTPPPGP-PAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREP 277
S SR SSS + + PGP P P G HGG+ + + P A P P
Sbjct: 421 RSLSRARSSSDSGSGRGAPGPGPEPGSERG----HGGHGKRAKERPPRARPASTSP 472
Score = 47.4 bits (111), Expect = 6e-05
Identities = 44/142 (30%), Positives = 57/142 (40%), Gaps = 19/142 (13%)
Query: 9 SSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHR 68
S+PS +G A R R RR+ AS + R R +PR +
Sbjct: 368 SAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRR-----RGRRRPRPAPP------ 416
Query: 69 DGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPAC 128
RG+ + RA S SGSG G G G + + G G RA PP P P+
Sbjct: 417 --RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS- 473
Query: 129 PGSSA--AAPEYKTLLISSLSP 148
PG+ PE K+ SS SP
Sbjct: 474 PGAHGRRGGPEGKS---SSRSP 492
Score = 36.2 bits (82), Expect = 0.14
Identities = 36/130 (27%), Positives = 46/130 (35%), Gaps = 22/130 (16%)
Query: 568 RSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERG 627
RS S G A G G RR+RR R R++ S R R + RG
Sbjct: 367 RSAPSSQGRGGRAAGGAG-------RRRRRRRRRRRSRSSASAPRRRGRRRPR-PAPPRG 418
Query: 628 SDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERN 687
S R+ R+R + S G S ERGH HGK+A++
Sbjct: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGS-----ERGH---------GGHGKRAKERPPR 464
Query: 688 HRTTEAEPKP 697
R P P
Sbjct: 465 ARPASTSPSP 474
Score = 35.8 bits (81), Expect = 0.18
Identities = 43/156 (27%), Positives = 55/156 (35%), Gaps = 30/156 (19%)
Query: 568 RSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDR-------GRTTHSPYEERSRTKGS 620
R RSRS R P+P R RSLS R GR P E +G
Sbjct: 392 RRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGH 451
Query: 621 GQQSERGSDRTPERSRKEN-------HSSEGTKE---------------SSSNSLSNSRH 658
G +R +R P R+R + H G E SSS S S SR
Sbjct: 452 GGHGKRAKER-PPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRS 510
Query: 659 GAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAE 694
+ E+ H + + +D E R +EAE
Sbjct: 511 RSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAE 546
Score = 33.9 bits (76), Expect = 0.69
Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 16/153 (10%)
Query: 568 RSVRSRSGERWGADGDRGLPKPWEER-------RKRRSLSSDRGRTTHSPYEERSRTKGS 620
R R + W + PK +++ RK+R L S+ + SP R + K
Sbjct: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPL--RKKKKSV 206
Query: 621 GQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKK 680
+ SD R R+ S K N H E G H H S G
Sbjct: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPH-TESPGRRSHRH-----SSGSS 260
Query: 681 ARDSERNHRTTEAEPKPLEEPKHETKKLKNLSE 713
S +H + P L PKH + K S+
Sbjct: 261 HSPSLSSHYSDSRSPSRL-SPKHRDEGRKTGSQ 292
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/122 (27%), Positives = 38/122 (31%), Gaps = 28/122 (22%)
Query: 7 RDSSPSGRGSSSSAKRPREREREAEAG-GRRAAHKASGGAKHPVPARARDKPRGSGSGGG 65
R SS SG G + P G G+RA + P RAR G
Sbjct: 427 RSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKER---------PPRARPASTSPSPGAH 477
Query: 66 GHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGM--------SPRASPLPP 117
G R G G+SS G R +S P S SP SP P
Sbjct: 478 GRRGG----------PEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK 527
Query: 118 PP 119
P
Sbjct: 528 KP 529
>gi|49087132 sal-like 2 [Homo sapiens]
Length = 1007
Score = 56.6 bits (135), Expect = 1e-07
Identities = 67/253 (26%), Positives = 95/253 (37%), Gaps = 34/253 (13%)
Query: 43 GGAKHPVPARARDKPRGSG----------------SGGGGHRDGRGTGDANHRASSGR-- 84
GG ++P + A +PR G SG D + S G
Sbjct: 67 GGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEESPGHFL 126
Query: 85 --SSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLL 142
++G+ AGGGG AS GA+ + P ++P PPPPPPP P P L+
Sbjct: 127 VAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIP----LI 182
Query: 143 ISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALA 202
+ L L+ R HQ + +I ++ LG+ P + +
Sbjct: 183 LEEL------RVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAP-ASPSELPGTGTASST 235
Query: 203 RQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAPADPLG-YLPLHGGYQY 261
+ LL P+K PV SS SSSSS+ A TP PLG P G
Sbjct: 236 KPLLPLFSPIK--PVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVG 293
Query: 262 KQRSLSPVAAPPL 274
+ +P +P L
Sbjct: 294 RSHKPTPAPSPAL 306
Score = 33.5 bits (75), Expect = 0.90
Identities = 34/158 (21%), Positives = 57/158 (36%), Gaps = 20/158 (12%)
Query: 2 KRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSG 61
+ S+ SG GS P+++ ++ + + + D G G
Sbjct: 733 QENGSEQSTVSGAGSF-----PQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRG 787
Query: 62 SGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPP 121
S GG + GD+ + + G+ A G + + + + S LPPPPPP
Sbjct: 788 SESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTT----QQSSLPPPPPP 843
Query: 122 PGAEPACP---GSS--------AAAPEYKTLLISSLSP 148
+ P GSS PE + S+L+P
Sbjct: 844 DSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTP 881
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 56.2 bits (134), Expect = 1e-07
Identities = 48/179 (26%), Positives = 85/179 (47%), Gaps = 13/179 (7%)
Query: 329 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGA-YAFLKFQNL 387
P T +L++G+L V+E L F G I + I R G + YA++ FQ+
Sbjct: 3 PSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHT 62
Query: 388 DMAHRAKVAMSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRF 441
A A M+ VI P++I + + +P+ R ++V L + + AL F
Sbjct: 63 KDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAF 122
Query: 442 GSIRTIDHVKGDS----FAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
G+I + + V ++ + ++ +E+ +AA+ A KM G L G R++ V K+ + R
Sbjct: 123 GNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNG--RKVFVGQFKSRKER 179
Score = 40.4 bits (93), Expect = 0.007
Identities = 58/282 (20%), Positives = 103/282 (36%), Gaps = 55/282 (19%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
N++I N + + L+ F K+G V + G+ + F+ F+ + A +A M
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 398 SGRVIGRNPIKIGYG-----------------KANPTTR-----LWVGGLGPNTSLAALA 435
+G+ + I +G K + TR L+V L L
Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLR 311
Query: 436 REFDRFGSIRT----IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAK 491
+ F FG+I + ++ + F ++ + S + A A +M G + + L V A+
Sbjct: 312 KAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVA--TKPLYVALAQ 369
Query: 492 AEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWT 551
+E R Q Y LT+ Y + + R PP G +
Sbjct: 370 RKEER--QAY-----------LTNEYMQRMASVRAVPNQRAPP------------SGYFM 404
Query: 552 SPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEER 593
+ + + S+ R R RW A G R P P++ +
Sbjct: 405 TAVPQTQNHAAYYPPSQIARLRPSPRWTAQGAR--PHPFQNK 444
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 55.8 bits (133), Expect = 2e-07
Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 18/160 (11%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
N+FI NLD S+ L F +G I + +G G YAF+ FQN A RA M
Sbjct: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKG-YAFVHFQNQSAADRAIEEM 157
Query: 398 SGRVIGRNPIKIG------------YGKANPTTRLWVGGLGPNTSLAALAREFDRFG--- 442
+G+++ + +G KA+ T +++ G + L F ++G
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTL 217
Query: 443 --SIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGG 480
+ T K F ++ ++S +AA+ A +M G + G
Sbjct: 218 SVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDING 257
Score = 45.4 bits (106), Expect = 2e-04
Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMS 398
L+I NLD ++ + +LR F +G I V + + GQ + + F + + A +A M+
Sbjct: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE-EGQSKGFGLICFSSPEDATKAMTEMN 353
Query: 399 GRVIGRNPIKI 409
GR++G P+ I
Sbjct: 354 GRILGSKPLSI 364
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 55.5 bits (132), Expect = 2e-07
Identities = 99/436 (22%), Positives = 158/436 (36%), Gaps = 95/436 (21%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMS 398
++IG L + E ++ R F+ YG I EV +K Y F++F +L A A ++
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK-------NGYGFVEFDDLRDADDAVYELN 56
Query: 399 G------RVI---GRNPI--------KIGYG-------KANPTT----RLWVGGLGPNTS 430
G RVI R P + GYG K P T RL V L S
Sbjct: 57 GKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCS 116
Query: 431 LAALAREFDRFGSIRTIDHVKG-DSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDF 489
L + G + D KG + I++ S + A K+ G + G RL D
Sbjct: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDK 176
Query: 490 AKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGD 549
+ R Y+R R+ R R +S + R+
Sbjct: 177 PGSRRRR-------------------SYSRSRSHSRSRSRSR------HSRKSRSRSGSS 211
Query: 550 WTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRT--- 606
+S SKS R S RSRS R + ++ P +E+ + RS S+ + R+
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKS-RSPSKEKSRSRSHSAGKSRSKSK 270
Query: 607 -----------------THSPYEERSRTKGSGQQSER----------GSDRTPERSRKEN 639
+ SP +S++K + ER R+ E+S +++
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQS 330
Query: 640 HS---SEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPK 696
S S+G S S S S S+ + R + S K R +R +
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS 390
Query: 697 PLEEPKHETKKLKNLS 712
++ K +T + ++ S
Sbjct: 391 SKKKKKEDTDRSQSRS 406
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/154 (25%), Positives = 69/154 (44%), Gaps = 9/154 (5%)
Query: 556 SSDRRNSLEGYSRSVRSRSGERWGADG-DRGLPKPWEERR-KRRSLSSDRGRTTHSPYEE 613
S R S E R RSRS + G+ R K ++R+ ++RS R R+ E
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
Query: 614 RSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSR-HGAEERGHHHHHHEA 672
RSR +GS + S+ GS + +K+ + S S S+S R H E E+
Sbjct: 376 RSRKRGSKRDSKAGS----SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGES 431
Query: 673 ADSSHGKKARDSERNHRTTEAEPKPLEEPKHETK 706
++ ++ R R++ ++++P E + +K
Sbjct: 432 ENAGTNQETRSRSRSN--SKSKPNLPSESRSRSK 463
Score = 35.4 bits (80), Expect = 0.24
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 551 TSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSP 610
T S+S S+ +S S +R G E R + RS S + + P
Sbjct: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK---PNLP 455
Query: 611 YEERSRTKGSGQ------QSERGSDRTPERSRKENHS 641
E RSR+K + + R + R+P RSR +HS
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 33.1 bits (74), Expect = 1.2
Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 2/114 (1%)
Query: 555 KSSDRRNSLEGYSRSVRSRSGER-WGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEE 613
K +R+S G S+ + +R R + K E + S RG + ++ +
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
Query: 614 RSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHH 667
+R++ + + + RSR ++ +S+ S S S S SR + R H
Sbjct: 439 ETRSRSRSNSKSKPNLPSESRSRSKS-ASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 32.3 bits (72), Expect = 2.0
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 2 KRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKA-SGGAKHPVPARARDKPRGS 60
KR E S S S S R R +R+++AG + K + ++ P+R+ K R
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
Query: 61 GSGGGGHRDGRGTGD 75
R+GRG +
Sbjct: 418 AKSESSQREGRGESE 432
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/299 (20%), Positives = 116/299 (38%), Gaps = 16/299 (5%)
Query: 420 LWVGGLGPNTSLA-ALAREFDRFGSIRTI----DHVKGDSFAYIQYESLDAAQAACAKMR 474
++VG L T+ A L F + G ++ + D + FA++++ ++ A A
Sbjct: 184 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALA-FN 242
Query: 475 GFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPP 534
G G DR L+++ + + P+ + E++ + A + +
Sbjct: 243 GVMFG--DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 300
Query: 535 HLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRS-----VRSRSGERWGADGDRGLPKP 589
+ R R+ S SKS RR + RS RSR +R +
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 590 WEERRKRRSL--SSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKE 647
ERRK RS S D+ + T +E+ R K ++ ER ++ E+ ++ + + KE
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 648 SSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSER-NHRTTEAEPKPLEEPKHET 705
+ + E H + ++ ++ ER R+ E + K ++ K T
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 479
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 16/177 (9%)
Query: 519 RHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSL-EGYSRSVRSRSGER 577
R ++ + D R+R H DRD+ + + DR + E + +SR+ R
Sbjct: 425 REKDKEKDREREREKEH--EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 482
Query: 578 WGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRK 637
+ R ERR+RRS SS R T + +S ++ +S D+ +R ++
Sbjct: 483 -SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKKDK--KREKE 538
Query: 638 ENHSSEGTKESSSNSL---SNSRHGAEERGHH------HHHHEAADSSHGKKARDSE 685
+H SE + S S+ SN R G E+ + H++ DSS K+ D +
Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 595
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/299 (20%), Positives = 116/299 (38%), Gaps = 16/299 (5%)
Query: 420 LWVGGLGPNTSLA-ALAREFDRFGSIRTI----DHVKGDSFAYIQYESLDAAQAACAKMR 474
++VG L T+ A L F + G ++ + D + FA++++ ++ A A
Sbjct: 68 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALA-FN 126
Query: 475 GFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPP 534
G G DR L+++ + + P+ + E++ + A + +
Sbjct: 127 GVMFG--DRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 184
Query: 535 HLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRS-----VRSRSGERWGADGDRGLPKP 589
+ R R+ S SKS RR + RS RSR +R +
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 590 WEERRKRRSL--SSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKE 647
ERRK RS S D+ + T +E+ R K ++ ER ++ E+ ++ + + KE
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 648 SSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSER-NHRTTEAEPKPLEEPKHET 705
+ + E H + ++ ++ ER R+ E + K ++ K T
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 363
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 16/177 (9%)
Query: 519 RHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSL-EGYSRSVRSRSGER 577
R ++ + D R+R H DRD+ + + DR + E + +SR+ R
Sbjct: 309 REKDKEKDREREREKEH--EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPR 366
Query: 578 WGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRK 637
+ R ERR+RRS SS R T + +S ++ +S D+ +R ++
Sbjct: 367 -SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKKDK--KREKE 422
Query: 638 ENHSSEGTKESSSNSL---SNSRHGAEERGHH------HHHHEAADSSHGKKARDSE 685
+H SE + S S+ SN R G E+ + H++ DSS K+ D +
Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 21/197 (10%)
Query: 301 ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY 360
ERALD +G+P + P + N+FI NLD S+ L F +
Sbjct: 66 ERALDTMNFDVIKGKPI---RIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAF 122
Query: 361 GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGY--------- 411
G I + G G YAF+ F+ + A +A M+G ++ + +G
Sbjct: 123 GNILSCKVVCDENGSKG-YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA 181
Query: 412 ---GKANPTTRLWVGGLGPNTSLAALAREFDRFG---SIRTIDHVKGDS--FAYIQYESL 463
KA T +++ G +L F +FG S++ + G S F ++ YE
Sbjct: 182 ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKH 241
Query: 464 DAAQAACAKMRGFPLGG 480
+ A A +M G + G
Sbjct: 242 EDANKAVEEMNGKEISG 258
Score = 53.5 bits (127), Expect = 8e-07
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGG-AYAFLKFQNLDMAHRAKVA 396
+L++G+L V+E L F G + + + R + YA++ FQ A RA
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 397 MSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRFGSIRT---- 446
M+ VI PI+I + + +P+ R +++ L + AL F FG+I +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 447 IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
D +A++ +E+ +AA A KM G L DR++ V K+ + R
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLN--DRKVFVGRFKSRKER 179
Score = 44.3 bits (103), Expect = 5e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEV-VIKRPARGQGGAYAFLKFQNLDMAHRAKVA 396
NL+I NLD ++ + +LR+ F +G I V+ R +G + F+ F + + A +A
Sbjct: 295 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKG--FGFVCFSSPEEATKAVTE 352
Query: 397 MSGRVIGRNPIKI 409
M+GR++G P+ +
Sbjct: 353 MNGRIVGSKPLYV 365
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 21/197 (10%)
Query: 301 ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY 360
ERALD +G+P + P + N+FI NLD S+ L F +
Sbjct: 66 ERALDTMNFDVIKGKPI---RIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAF 122
Query: 361 GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGY--------- 411
G I + G G YAF+ F+ + A +A M+G ++ + +G
Sbjct: 123 GNILSCKVVCDENGSKG-YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA 181
Query: 412 ---GKANPTTRLWVGGLGPNTSLAALAREFDRFG---SIRTIDHVKGDS--FAYIQYESL 463
KA T +++ G +L F +FG S++ + G S F ++ YE
Sbjct: 182 ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKH 241
Query: 464 DAAQAACAKMRGFPLGG 480
+ A A +M G + G
Sbjct: 242 EDANKAVEEMNGKEISG 258
Score = 53.5 bits (127), Expect = 8e-07
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGG-AYAFLKFQNLDMAHRAKVA 396
+L++G+L V+E L F G + + + R + YA++ FQ A RA
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 397 MSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRFGSIRT---- 446
M+ VI PI+I + + +P+ R +++ L + AL F FG+I +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 447 IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
D +A++ +E+ +AA A KM G L DR++ V K+ + R
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLN--DRKVFVGRFKSRKER 179
Score = 44.3 bits (103), Expect = 5e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEV-VIKRPARGQGGAYAFLKFQNLDMAHRAKVA 396
NL+I NLD ++ + +LR+ F +G I V+ R +G + F+ F + + A +A
Sbjct: 295 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKG--FGFVCFSSPEEATKAVTE 352
Query: 397 MSGRVIGRNPIKI 409
M+GR++G P+ +
Sbjct: 353 MNGRIVGSKPLYV 365
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 21/197 (10%)
Query: 301 ERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKY 360
ERALD +G+P + P + N+FI NLD S+ L F +
Sbjct: 66 ERALDTMNFDVIKGKPI---RIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAF 122
Query: 361 GIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGY--------- 411
G I + G G YAF+ F+ + A +A M+G ++ + +G
Sbjct: 123 GNILSCKVVCDENGSKG-YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA 181
Query: 412 ---GKANPTTRLWVGGLGPNTSLAALAREFDRFG---SIRTIDHVKGDS--FAYIQYESL 463
KA T +++ G +L F +FG S++ + G S F ++ YE
Sbjct: 182 ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKH 241
Query: 464 DAAQAACAKMRGFPLGG 480
+ A A +M G + G
Sbjct: 242 EDANKAVEEMNGKEISG 258
Score = 53.5 bits (127), Expect = 8e-07
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGG-AYAFLKFQNLDMAHRAKVA 396
+L++G+L V+E L F G + + + R + YA++ FQ A RA
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 397 MSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRFGSIRT---- 446
M+ VI PI+I + + +P+ R +++ L + AL F FG+I +
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 447 IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
D +A++ +E+ +AA A KM G L DR++ V K+ + R
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLN--DRKVFVGRFKSRKER 179
Score = 44.3 bits (103), Expect = 5e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEV-VIKRPARGQGGAYAFLKFQNLDMAHRAKVA 396
NL+I NLD ++ + +LR+ F +G I V+ R +G + F+ F + + A +A
Sbjct: 295 NLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKG--FGFVCFSSPEEATKAVTE 352
Query: 397 MSGRVIGRNPIKI 409
M+GR++G P+ +
Sbjct: 353 MNGRIVGSKPLYV 365
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 53.5 bits (127), Expect = 8e-07
Identities = 80/317 (25%), Positives = 116/317 (36%), Gaps = 89/317 (28%)
Query: 22 RPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRAS 81
RPR++ + A + +S A P DK GSGGGGH G G G +N
Sbjct: 129 RPRKKVKSGNA------NSSSSAAASSKPGEKGDKV--GGSGGGGHGGGGGGGSSNAGGG 180
Query: 82 SGRSSGSGA-------------------------------GGGGRGGKASGDPGASGMSP 110
G +SG GA GGG GGKA+ AS +
Sbjct: 181 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE 240
Query: 111 RASPLPPPPPPPGAE------PACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFK 164
+A P A+ P +SA+A + +S + A P +HL ++ +
Sbjct: 241 QAGAAALLPLGAAADHHSLYKARTPSASASA---SSAASASAALAAPGKHLAEKKVKRVY 297
Query: 165 RFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGG 224
FG + S +G A P D L LY+ G G
Sbjct: 298 LFGGLGTSSSPVGGVGAGA-----DPSD-----------PLGLYEE---------EGAGC 332
Query: 225 SSRRSSSS--SAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHA 282
S S S S+AAS+P G +PAD GY L AA P HA
Sbjct: 333 SPDAPSLSGRSSAASSPAAG-RSPADHRGYASLR-------------AASPAPSSAPSHA 378
Query: 283 AAAFALDAAAAAAVGLS 299
+++ + ++++++ G S
Sbjct: 379 SSSASSHSSSSSSSGSS 395
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 53.5 bits (127), Expect = 8e-07
Identities = 65/254 (25%), Positives = 93/254 (36%), Gaps = 28/254 (11%)
Query: 411 YGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKG-DSFAYIQYESLDAAQAA 469
YG+ T+++VG LG L R F +G +RT+ + FA++++E A+ A
Sbjct: 4 YGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDA 63
Query: 470 CAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVR 529
+ G + G R+ + +R+ + P + G H D
Sbjct: 64 VRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCH--- 120
Query: 530 DRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKP 589
YS R R+ S S+S RR YSRS RSRS RG
Sbjct: 121 -------RYSRRRRS--RSRSRSHSRSRGRR-----YSRS-RSRS---------RGRRSR 156
Query: 590 WEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESS 649
R+ RS+S R R+ KGS R+ RS SS S
Sbjct: 157 SASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSP 216
Query: 650 SNSLSNSRHGAEER 663
S S S G+ R
Sbjct: 217 SPKRSRSPSGSPRR 230
Score = 37.0 bits (84), Expect = 0.082
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMS 398
+++GNL + EL RAF YG + V I R G +AF++F++ A A +
Sbjct: 13 VYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPG----FAFVEFEDPRDAEDAVRGLD 68
Query: 399 GRVIGRNPIKIGYGKANP 416
G+VI + +++ P
Sbjct: 69 GKVICGSRVRVELSTGMP 86
Score = 31.2 bits (69), Expect = 4.5
Identities = 32/115 (27%), Positives = 46/115 (40%), Gaps = 8/115 (6%)
Query: 28 REAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSG 87
R + R +H S G ++ +R+R + RG S R R R++S R S
Sbjct: 124 RRRRSRSRSRSHSRSRGRRY---SRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSR 180
Query: 88 SGAGGGGR---GGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGS--SAAAPE 137
SG+ G R S S PR+S P P + GS +A+PE
Sbjct: 181 SGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPE 235
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 53.5 bits (127), Expect = 8e-07
Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 4/151 (2%)
Query: 558 DRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRT 617
D R E R R + ER + +R + EER K R+ +R + + S SRT
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 618 KGSGQQSERGSDRTPERSRKENHS-SEGTKESSSNSLSNSRHGAEERGHHHHHHEAADS- 675
S ++ R D RSR+ S S + S S+ S +H + R S
Sbjct: 304 --SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 676 SHGKKARDSERNHRTTEAEPKPLEEPKHETK 706
H K+RD E++ ++ E E + ++ K K
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/151 (23%), Positives = 60/151 (39%), Gaps = 9/151 (5%)
Query: 562 SLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSG 621
++E +R R+ E D D L K +ER +R +R R E + R +
Sbjct: 226 TVEELKEKLRKRTEE---PDRDERLKKEKQEREEREK-EREREREER---ERKRRREEEE 278
Query: 622 QQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKA 681
++ ER DR ER ++ S + +S S SR R + D +
Sbjct: 279 REKERARDR--ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 682 RDSERNHRTTEAEPKPLEEPKHETKKLKNLS 712
SER HR+ + + + ++ K ++ S
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKS 367
Score = 38.9 bits (89), Expect = 0.021
Identities = 39/125 (31%), Positives = 57/125 (45%), Gaps = 18/125 (14%)
Query: 554 SKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTH-SPYE 612
S++SDRR S + RSRS ER + R +RRS S DR H S
Sbjct: 301 SRTSDRRCSRSRDHK--RSRSRER----------RRSRSRDRRRSRSHDRSERKHRSRSR 348
Query: 613 ERSRTKGSGQQS--ERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHH 670
+R R+K ++S R R E+ RK S E K S + S+ + G+ E+ +
Sbjct: 349 DRRRSKSRDRKSYKHRSKSRDREQDRK---SKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 671 EAADS 675
E+ +S
Sbjct: 406 ESKES 410
Score = 32.0 bits (71), Expect = 2.6
Identities = 34/172 (19%), Positives = 57/172 (33%), Gaps = 20/172 (11%)
Query: 540 DRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSL 599
DRD + + +R E R R ER ++ + E R++ RS
Sbjct: 242 DRDERLKKEKQEREEREKEREREREERERKRRREEEER-----EKERARDRERRKRSRSR 296
Query: 600 SSDRGRTT-----------HSPYEERSRTKGSGQQSERGSDRTPE----RSRKENHSSEG 644
S RT+ S ER R++ ++ R DR+ RSR S
Sbjct: 297 SRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSR 356
Query: 645 TKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPK 696
++S + + + + + D K+ E+ T E K
Sbjct: 357 DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK 408
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 53.5 bits (127), Expect = 8e-07
Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 4/151 (2%)
Query: 558 DRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRT 617
D R E R R + ER + +R + EER K R+ +R + + S SRT
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 618 KGSGQQSERGSDRTPERSRKENHS-SEGTKESSSNSLSNSRHGAEERGHHHHHHEAADS- 675
S ++ R D RSR+ S S + S S+ S +H + R S
Sbjct: 304 --SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 676 SHGKKARDSERNHRTTEAEPKPLEEPKHETK 706
H K+RD E++ ++ E E + ++ K K
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Score = 39.7 bits (91), Expect = 0.013
Identities = 35/151 (23%), Positives = 60/151 (39%), Gaps = 9/151 (5%)
Query: 562 SLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSG 621
++E +R R+ E D D L K +ER +R +R R E + R +
Sbjct: 226 TVEELKEKLRKRTEE---PDRDERLKKEKQEREEREK-EREREREER---ERKRRREEEE 278
Query: 622 QQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKA 681
++ ER DR ER ++ S + +S S SR R + D +
Sbjct: 279 REKERARDR--ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 682 RDSERNHRTTEAEPKPLEEPKHETKKLKNLS 712
SER HR+ + + + ++ K ++ S
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKS 367
Score = 38.9 bits (89), Expect = 0.021
Identities = 39/125 (31%), Positives = 57/125 (45%), Gaps = 18/125 (14%)
Query: 554 SKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTH-SPYE 612
S++SDRR S + RSRS ER + R +RRS S DR H S
Sbjct: 301 SRTSDRRCSRSRDHK--RSRSRER----------RRSRSRDRRRSRSHDRSERKHRSRSR 348
Query: 613 ERSRTKGSGQQS--ERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHH 670
+R R+K ++S R R E+ RK S E K S + S+ + G+ E+ +
Sbjct: 349 DRRRSKSRDRKSYKHRSKSRDREQDRK---SKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 671 EAADS 675
E+ +S
Sbjct: 406 ESKES 410
Score = 32.0 bits (71), Expect = 2.6
Identities = 34/172 (19%), Positives = 57/172 (33%), Gaps = 20/172 (11%)
Query: 540 DRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSL 599
DRD + + +R E R R ER ++ + E R++ RS
Sbjct: 242 DRDERLKKEKQEREEREKEREREREERERKRRREEEER-----EKERARDRERRKRSRSR 296
Query: 600 SSDRGRTT-----------HSPYEERSRTKGSGQQSERGSDRTPE----RSRKENHSSEG 644
S RT+ S ER R++ ++ R DR+ RSR S
Sbjct: 297 SRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSR 356
Query: 645 TKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPK 696
++S + + + + + D K+ E+ T E K
Sbjct: 357 DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESK 408
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 13/170 (7%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGG-AYAFLKFQNLDMAHRAKVA 396
+L++G+L V+E L F G I + + R + YA++ FQ A RA
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 397 MSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRFGSIRT---- 446
M+ VI P++I + + +P+ R +++ L + AL F FG+I +
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 447 IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
D + ++ +E+ +AA+ A KM G L DR++ V K+ + R
Sbjct: 132 CDENGSKGYGFVHFETQEAAERAIEKMNGMLLN--DRKVFVGRFKSRKER 179
Score = 42.0 bits (97), Expect = 0.003
Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
NL++ NLD + + LR+ F +G I + G+ + F+ F + + A +A M
Sbjct: 295 NLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 398 SGRVIGRNPIKI 409
+GR++ P+ +
Sbjct: 354 NGRIVATKPLYV 365
Score = 40.0 bits (92), Expect = 0.010
Identities = 35/164 (21%), Positives = 65/164 (39%), Gaps = 26/164 (15%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
N++I N + + L+ F K+G V + G+ + F+ F+ + A +A M
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 398 SGRVIGRNPIKIGYG-----------------KANPTTR-----LWVGGLGPNTSLAALA 435
+G+ + I +G K + TR L+V L L
Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
Query: 436 REFDRFGSIRT----IDHVKGDSFAYIQYESLDAAQAACAKMRG 475
+EF FG+I + ++ + F ++ + S + A A +M G
Sbjct: 312 KEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 13/170 (7%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRP-ARGQGGAYAFLKFQNLDMAHRAKVA 396
+L++G+L V+E L F G I + + R A + YA++ FQ A RA
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 397 MSGRVIGRNPIKIGYGKANPTTR------LWVGGLGPNTSLAALAREFDRFGSIRT---- 446
M+ ++ PI+I + + +P R +++ L + AL F FG+I +
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
Query: 447 IDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETR 496
D F ++ +E+ +AAQ A M G L DR++ V K+ R
Sbjct: 132 CDEHGSRGFGFVHFETHEAAQQAINTMNGMLLN--DRKVFVGHFKSRRER 179
Score = 48.5 bits (114), Expect = 3e-05
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
NL++ NLD S+ + +LR+ F YG+I + G + F+ F + + A +A M
Sbjct: 295 NLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG-GHSKGFGFVCFSSPEEATKAVTEM 353
Query: 398 SGRVIGRNPIKI 409
+GR++G P+ +
Sbjct: 354 NGRIVGTKPLYV 365
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/156 (33%), Positives = 62/156 (39%), Gaps = 21/156 (13%)
Query: 7 RDSSPSGRGSSSSAKRPREREREA--EAGGRRAAHKASGGAKHPVPA----RARDKPRGS 60
R P+ GS SSA +E EA + RRA + GG V R KPR
Sbjct: 662 RWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLG 721
Query: 61 GSGGGGHRDGRGTGDANHRASSGRSSGSGA--------GGGG----RGGKA---SGDPGA 105
S GGG RG+G A R S G S SG GGGG RGG A SG+
Sbjct: 722 KSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAV 781
Query: 106 SGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTL 141
+ +A+ PP G AAA K L
Sbjct: 782 TAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGKKPL 817
Score = 39.7 bits (91), Expect = 0.013
Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 22/122 (18%)
Query: 12 SGRGSSSSAKRPREREREAEAGGRRAAHKASG----------------GAKHPVPARARD 55
S RG ++ R R ++A GG+ K+ G GAK A A +
Sbjct: 237 SRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGE 296
Query: 56 KPRGSGSGG------GGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMS 109
KP G GG GG G G R +++ + A G RGG G+
Sbjct: 297 KPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVK 356
Query: 110 PR 111
R
Sbjct: 357 SR 358
Score = 36.6 bits (83), Expect = 0.11
Identities = 40/139 (28%), Positives = 57/139 (41%), Gaps = 28/139 (20%)
Query: 2 KRQSERDSSPSGRGS------SSSAKRPREREREAEAGGRR--AAHKASGGAKHP---VP 50
K+Q + +S +G S S S K R ++AEA G + AA S G K P P
Sbjct: 472 KKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKP 531
Query: 51 ARARDKPRGSGS----------------GGGGHRDGRGTGDANHRASSGRSSGSGAGGGG 94
A A K R GS GGGG++ RG G N G+++ + GG
Sbjct: 532 AVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRG-GGGNKPRQWGQTAAAAKTRGG 590
Query: 95 RGGKASGDPGASGMSPRAS 113
+ A+G++ S
Sbjct: 591 GDKQPGWQKAAAGVTKSRS 609
Score = 35.8 bits (81), Expect = 0.18
Identities = 39/148 (26%), Positives = 55/148 (37%), Gaps = 44/148 (29%)
Query: 6 ERDSSPSGRGSSS-SAKRPRE-------------REREAEA------GGRRAAHK----- 40
E+ + G+ S S K+PR R+REA++ GGRR H+
Sbjct: 172 EKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPA 231
Query: 41 ------ASGGAKHPVPARARDKPRGSG-------SGGGG----HRDGRGTGDANHRASSG 83
GG K P R R + +G S GGG R G+ A +
Sbjct: 232 AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGA 291
Query: 84 RSSGSGAGGGGRGGKASGDPGASGMSPR 111
++G GRGG+ G G +PR
Sbjct: 292 ATAGEKPAAKGRGGR--GPKSLGGQNPR 317
Score = 35.4 bits (80), Expect = 0.24
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 2 KRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSG 61
+R + S G+ S K+PR R ++A A ++ G K R + G+
Sbjct: 429 RRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQ---GRQKASAAGTK 485
Query: 62 SGGGGHRD--GRGTGDANHRASSGRSSGSGAGGGGRGGK 98
S GGG + G+ +A + + AG RG K
Sbjct: 486 SRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRK 524
Score = 35.4 bits (80), Expect = 0.24
Identities = 38/134 (28%), Positives = 53/134 (39%), Gaps = 29/134 (21%)
Query: 2 KRQSERDSSPSGRGSSSSA-------KRPREREREAEAGGRRAAHKASGGAKHP----VP 50
K+ R + G G ++A +R ++ GG A + SGGAK
Sbjct: 687 KKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAK 746
Query: 51 ARARDKPRGSGSGGGGHRDGRGTGDANHRA-----SSGRSSGSGAGG---------GGRG 96
+R+ K S S GGG R G A R+ ++G + AGG GGRG
Sbjct: 747 SRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRG 806
Query: 97 GKASGDPGASGMSP 110
KA+ A G P
Sbjct: 807 QKAA----AGGKKP 816
Score = 33.1 bits (74), Expect = 1.2
Identities = 37/151 (24%), Positives = 49/151 (32%), Gaps = 24/151 (15%)
Query: 3 RQSERDSSPSGRGSSSSAKRPR------EREREAEAGGRRAAHKASGGAKHP-------- 48
R+ R +P R + A +PR R R +A R SGG K P
Sbjct: 399 RKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKAR 458
Query: 49 -----VPARAR-DKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGD 102
A +R DK +G RG G +H + G A G A+G
Sbjct: 459 QKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGA 518
Query: 103 PGASGMSPRASPLPPPPPPPGAEPACPGSSA 133
PR P GA+ GS +
Sbjct: 519 KSRGRKQPRRQ----KPAVAGAKSRVGGSKS 545
Score = 32.3 bits (72), Expect = 2.0
Identities = 32/120 (26%), Positives = 41/120 (34%), Gaps = 15/120 (12%)
Query: 7 RDSSPSGRGSSSSA---KRPREREREAEAGGRR------------AAHKASGGAKHPVPA 51
R P RG ++A K+PR R +++ A G + A K+ GG K A
Sbjct: 119 RGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAA 178
Query: 52 RARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPR 111
A K R RG D R +S GG R P A G R
Sbjct: 179 AAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSR 238
Score = 30.8 bits (68), Expect = 5.8
Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 23/111 (20%)
Query: 10 SPSGRGSSSSAKRPREREREAEAGGR-----RAAHKASGGAKHPVPARARDKPRGSGSGG 64
S GRG ++PR R ++A A G RA A+ G+K+ RG+G+
Sbjct: 115 SLGGRG-----RKPRRRGQKAAATGSKKPRWRAQKSAAAGSKN----------RGAGAQK 159
Query: 65 GGHRDG---RGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRA 112
G +G A++G S SG RG K+ GD G A
Sbjct: 160 AAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREA 210
Score = 30.8 bits (68), Expect = 5.8
Identities = 35/131 (26%), Positives = 52/131 (39%), Gaps = 16/131 (12%)
Query: 568 RSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERG 627
R R++S G + G+ PW+ R K+ L RG ++++GSG RG
Sbjct: 690 RRRRAKSRGDGGQNAAVGI-NPWQRRGKKPRLGKSRGGGG-------AKSRGSGGAKSRG 741
Query: 628 SDRTPERSRK-----ENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKAR 682
S RS K ++H G K + SR G E+ +AA + K R
Sbjct: 742 SGGAKSRSGKKAAASKSHGGGGAKRRRGGG-AKSRSG--EKAVTAGGQKAAAAGGKKPPR 798
Query: 683 DSERNHRTTEA 693
R R +A
Sbjct: 799 VKSRGGRGQKA 809
Score = 30.4 bits (67), Expect = 7.6
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 26 REREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRS 85
R ++A AGG++A + GA AR + + +G+GG + RG G+ A+ +S
Sbjct: 60 RRQKAAAGGKKARLRGQKGAVAGKEARQHWQ-KAAGAGGA---ENRGGGEQKAAAAGTKS 115
Query: 86 SGSGAGGGGRGGKASGDPGAS 106
GG GR + G A+
Sbjct: 116 ----LGGRGRKPRRRGQKAAA 132
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEV--VIKRPARGQGGAYAFLKFQNLDMAHRAKV 395
N+FIGNLD + E L F +G+I + +++ P G YAF+ F + D + A
Sbjct: 101 NIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIE 160
Query: 396 AMSGRVIGRNPIKIGY 411
AM+G+ + PI + Y
Sbjct: 161 AMNGQYLCNRPITVSY 176
Score = 47.8 bits (112), Expect = 5e-05
Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 13/160 (8%)
Query: 329 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYG-IIEEVVIKRPARGQGGAYAFLKFQNL 387
P ++ +++G LD VSE L F + G ++ + K GQ Y F++F +
Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
Query: 388 DMAHRAKVAMSGRVIGRNPIKIGYGKANPTT-----RLWVGGLGPNTSLAALAREFDRFG 442
+ A A M+ + PI++ A+ +++G L P L F FG
Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFG 124
Query: 443 SI-------RTIDHVKGDSFAYIQYESLDAAQAACAKMRG 475
I R D +A+I + S DA+ AA M G
Sbjct: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNG 164
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/94 (31%), Positives = 36/94 (38%), Gaps = 19/94 (20%)
Query: 50 PARARDKPRGSGSGGGGHRDGRG--------TGDANHRASSGRSSGSGAGGGGRGGKASG 101
P A P +G+ G GH G G G H S + + G G G +G
Sbjct: 268 PGAAGHGPPSAGTPGAGH-PGHGHSHPHPFPPGGMPHPGMS-QMQLAHHGPHGLGHPHAG 325
Query: 102 DPGASGMSPRASPLPPP------PPPPGAEPACP 129
PG+ G P P PPP PPP G P P
Sbjct: 326 PPGSGGQPP---PRPPPGMPHPGPPPMGMPPRGP 356
Score = 30.4 bits (67), Expect = 7.6
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 6/35 (17%)
Query: 106 SGMSPRASP----LPPPPPPPGAEPACPGSSAAAP 136
SG+ P P PPP PPPGA P PG A P
Sbjct: 230 SGLPPPGMPPPGSFPPPVPPPGALP--PGIPPAMP 262
>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
[Homo sapiens]
Length = 285
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 12/172 (6%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKR-PARGQGGAYAFLKFQNLDMAHRAKVAM 397
+F+G L S+ +L+ F K+G + + IK P G+ + F+ F++ +
Sbjct: 72 MFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQK 131
Query: 398 SGRVIGR--NPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHV----- 450
R+ GR +P K K +P +++VGGL P + + F FG I I+
Sbjct: 132 EHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKL 191
Query: 451 -KGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQY 501
K F +I ++ + + K G + + A+ +E QQY
Sbjct: 192 NKRRGFVFITFKEEEPVKKVLEKKFHTVSGS---KCEIKVAQPKEVYQQQQY 240
Score = 30.4 bits (67), Expect = 7.6
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 72 GTGDANHRASSGRSSGSGAGGGGRGGKASG 101
G+G +R R SG G GGGG+G G
Sbjct: 241 GSGGRGNRNRGNRGSGGGGGGGGQGSTNYG 270
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 12/172 (6%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEEVVIKR-PARGQGGAYAFLKFQNLDMAHRAKVAM 397
+F+G L S+ +L+ F K+G + + IK P G+ + F+ F++ +
Sbjct: 72 MFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQK 131
Query: 398 SGRVIGR--NPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHV----- 450
R+ GR +P K K +P +++VGGL P + + F FG I I+
Sbjct: 132 EHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKL 191
Query: 451 -KGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQY 501
K F +I ++ + + K G + + A+ +E QQY
Sbjct: 192 NKRRGFVFITFKEEEPVKKVLEKKFHTVSGS---KCEIKVAQPKEVYQQQQY 240
>gi|148612890 serine-arginine repressor protein [Homo sapiens]
Length = 261
Score = 51.6 bits (122), Expect = 3e-06
Identities = 67/265 (25%), Positives = 109/265 (41%), Gaps = 28/265 (10%)
Query: 416 PTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGD-------SFAYIQYESLDAAQA 468
P T L++ + T L REF R+G I + ++ D FAY+Q+E + A+
Sbjct: 8 PNTSLFIRNVADATRPEDLRREFGRYGPIVDV-YIPLDFYTRRPRGFAYVQFEDVRDAED 66
Query: 469 ACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV----HYELLTDGYTRHRNLD 524
A + + G R++ + FA+ + Q P H + R R+
Sbjct: 67 ALYNLNRKWVCG--RQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSPSQRRTRSRS 124
Query: 525 ADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDR 584
+ R+R L R R F S SKS RR++ SR+ R G R R
Sbjct: 125 SSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRNFGSR-----GR 179
Query: 585 GLPKPWEERRKR--RSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSS 642
K ++R K +S SS + T S + RS + S + R+P +S K +S
Sbjct: 180 SRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIA-----RSPCKSPKGYTNS 234
Query: 643 EGTKESSSNSLSNSRHGAEERGHHH 667
E +++ + S+ R + R + H
Sbjct: 235 ETKVQTAKH--SHFRSHSRSRSYRH 257
Score = 30.0 bits (66), Expect = 10.0
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 9/86 (10%)
Query: 338 NLFIGNLDHSVSEVELRRAFEKYGIIEEVVI-----KRPARGQGGAYAFLKFQNLDMAHR 392
+LFI N+ + +LRR F +YG I +V I R RG +A+++F+++ A
Sbjct: 11 SLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRG----FAYVQFEDVRDAED 66
Query: 393 AKVAMSGRVIGRNPIKIGYGKANPTT 418
A ++ + + I+I + + + T
Sbjct: 67 ALYNLNRKWVCGRQIEIQFAQGDRKT 92
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 51.6 bits (122), Expect = 3e-06
Identities = 47/176 (26%), Positives = 82/176 (46%), Gaps = 21/176 (11%)
Query: 339 LFIGNLDHSVSEVELRRAFEKYGIIEE-VVIKRPARGQGGAYAFLKFQNLDMAHRAKVAM 397
LFIG L+ SE LR FE +G + + VV+ P + + F+ + N++ A A +A
Sbjct: 9 LFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAA-MAA 67
Query: 398 SGRVIGRNPIKIGYG-----KANP-----TTRLWVGGLGPNTSLAALAREFDRFGSIRTI 447
S + N +++ A P +L+VGGL + + L F +FG++
Sbjct: 68 SPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKA 127
Query: 448 DHV------KGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRY 497
+ + K F ++ +++ DAA A A ++ P+ G R+ V A +E Y
Sbjct: 128 EIIADKQSGKKRGFGFVYFQNHDAADKA-AVVKFHPIQG--HRVEVKKAVPKEDIY 180
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 321 AVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEV-VIKRPARGQGGAY 379
AV ED + LF+G L V+E +L F ++G +E+ +I G+ +
Sbjct: 82 AVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGF 141
Query: 380 AFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLG 426
F+ FQN D A +A V + G ++ KA P ++ GG G
Sbjct: 142 GFVYFQNHDAADKAAVVKFHPIQGH---RVEVKKAVPKEDIYSGGGG 185
Score = 36.6 bits (83), Expect = 0.11
Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 19/92 (20%)
Query: 37 AAHKASGGAKHPVPARARDKPRG-------SGSGGGGHRDGRG----TGDANHRASSGRS 85
AA KA+ HP+ + + SG GGGG R RG G R +G S
Sbjct: 151 AADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLS 210
Query: 86 SGSGAG--------GGGRGGKASGDPGASGMS 109
G G G GGG GG + G G S
Sbjct: 211 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSS 242
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 7/88 (7%)
Query: 14 RGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGT 73
+G K+ +E GG + + GG RD+ S GGGG+ G
Sbjct: 164 QGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGY 223
Query: 74 GDANHRASSGRSSGSGAGGGGRGGKASG 101
G G G A GGG GG + G
Sbjct: 224 G-------GGGGGGYNAYGGGGGGSSYG 244
Score = 32.0 bits (71), Expect = 2.6
Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 57 PRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKA 99
P SG GGGG G R++SG G GGGG GG +
Sbjct: 267 PMKSGGGGGG-----GGSSWGGRSNSGPYRGGYGGGGGYGGSS 304
Score = 31.2 bits (69), Expect = 4.5
Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 17/124 (13%)
Query: 1 MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGR--RAAHKASGGAKHPVPARARD--- 55
+K+ ++ SG G S R GGR K GG +
Sbjct: 170 VKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGG 229
Query: 56 --KPRGSGSGG---GGHRDGRGTGD----ANHRASSG---RSSGSGAGGGGRGGKASGDP 103
G G GG GG G G G + H++S G G G GG GG+++ P
Sbjct: 230 GYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGP 289
Query: 104 GASG 107
G
Sbjct: 290 YRGG 293
Score = 30.4 bits (67), Expect = 7.6
Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 6/59 (10%)
Query: 419 RLWVGGLGPNTSLAALAREFDRFGSIRTIDHV------KGDSFAYIQYESLDAAQAACA 471
+L++GGL TS + L F+ FG++ V + F ++ Y +++ A AA A
Sbjct: 8 KLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMA 66
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 50.8 bits (120), Expect = 5e-06
Identities = 37/111 (33%), Positives = 44/111 (39%), Gaps = 23/111 (20%)
Query: 11 PSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDG 70
P G +SS RP E GG + H+ G P GS GGGGHR
Sbjct: 757 PGGGMGNSSGHRPHE----GPGGGMGSGHRPHEG------------PGGSMGGGGGHRPH 800
Query: 71 RG-----TGDANHRASSGRSSGSGAGGGGRGGKASGDP--GASGMSPRASP 114
G +G + HR G G GAGGG R + G G+ G P P
Sbjct: 801 EGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGP 851
Score = 43.9 bits (102), Expect = 7e-04
Identities = 38/127 (29%), Positives = 40/127 (31%), Gaps = 26/127 (20%)
Query: 14 RGSSSSAKRPREREREAEAGGRRAA-----HKASGGAKHPVPARARDKPRGSGSGGGGHR 68
RG P R R G A GG P R P G GGGGHR
Sbjct: 693 RGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHR 752
Query: 69 DGRGTG-----DANHRASSGRSSGSGAG-----------GGGRG-----GKASGDPGASG 107
G G + HR G G G+G GGG G G G G SG
Sbjct: 753 PHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSG 812
Query: 108 MSPRASP 114
P P
Sbjct: 813 HRPHEGP 819
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/107 (32%), Positives = 38/107 (35%), Gaps = 7/107 (6%)
Query: 15 GSSSSAKRPREREREAEAGG--RRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRG 72
G S RP E + GG R GG R + P G GGGHR G
Sbjct: 775 GGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEG 834
Query: 73 TGDANHRASSGRSSGSGAGGGGRGGKASGD-PGASGMSPRASPLPPP 118
G + S G G G GG G D PG G R PPP
Sbjct: 835 PG-GSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRG---PPP 877
Score = 35.8 bits (81), Expect = 0.18
Identities = 35/111 (31%), Positives = 38/111 (34%), Gaps = 14/111 (12%)
Query: 11 PSGRGSSSSAKRPREREREAE-AGGRRAAHKASGGAKHPVPARARDKPRGSGSGGG---- 65
P G S S RP E AGG H+ GG+ + G G G
Sbjct: 803 PGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPH 862
Query: 66 ---GHR--DGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPR 111
GHR D RG HR G G GGGG G G MS R
Sbjct: 863 DVPGHRGHDHRGPPPHEHRG----HDGPGHGGGGHRGHDGGHSHGGDMSNR 909
Score = 32.0 bits (71), Expect = 2.6
Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 15/94 (15%)
Query: 43 GGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGD 102
GG PV R P GG DG G G G G GRGG+ +
Sbjct: 656 GGPGGPVGPRLLGPPPPP-RGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNE 714
Query: 103 PGASGMSPRASPLPPPPPPPGAEPACPGSSAAAP 136
P PPPPP A G S P
Sbjct: 715 P--------------PPPPPPFRGARGGRSGGGP 734
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,144,912
Number of Sequences: 37866
Number of extensions: 2448831
Number of successful extensions: 46755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 874
Number of HSP's successfully gapped in prelim test: 1429
Number of HSP's that attempted gapping in prelim test: 21782
Number of HSP's gapped (non-prelim): 17418
length of query: 890
length of database: 18,247,518
effective HSP length: 111
effective length of query: 779
effective length of database: 14,044,392
effective search space: 10940581368
effective search space used: 10940581368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.