Search of human proteins with 5453746

Search of human proteins with 5453746

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453746 5,10-methenyltetrahydrofolate synthetase
(5-formyltetrahydrofolate cyclo-ligase) [Homo sapiens]
         (203 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453746 5,10-methenyltetrahydrofolate synthetase (5-formyltet...   403   e-113
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]             32   0.48 
gi|110349756 zygin 2 isoform 2 [Homo sapiens]                          32   0.48 
gi|110349754 zygin 2 isoform 1 [Homo sapiens]                          32   0.48 
gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10 iso...    31   0.63 
gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isof...    31   0.63 
gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo sapi...    29   2.4  
gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo sapi...    29   2.4  
gi|116875765 tight junction protein 1 isoform b [Homo sapiens]         29   3.1  
gi|116875767 tight junction protein 1 isoform a [Homo sapiens]         29   3.1  
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    28   5.3  
gi|76496497 artemis protein isoform a [Homo sapiens]                   28   7.0  
gi|44955929 calmodulin regulated spectrin-associated protein 1-l...    28   7.0  
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]     27   9.1  

>gi|5453746 5,10-methenyltetrahydrofolate synthetase
           (5-formyltetrahydrofolate cyclo-ligase) [Homo sapiens]
          Length = 203

 Score =  403 bits (1036), Expect = e-113
 Identities = 203/203 (100%), Positives = 203/203 (100%)

Query: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
           MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD
Sbjct: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60

Query: 61  EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120
           EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR
Sbjct: 61  EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120

Query: 121 EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC 180
           EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC
Sbjct: 121 EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC 180

Query: 181 LQVPVNENDMKVDEVLYEDSSTA 203
           LQVPVNENDMKVDEVLYEDSSTA
Sbjct: 181 LQVPVNENDMKVDEVLYEDSSTA 203


>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
          Length = 1133

 Score = 31.6 bits (70), Expect = 0.48
 Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 4    AAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIE 63
            AA+   ++ LR E K+R+ A +   +LR   V S   +A  +Y++ +R ++  + Q + E
Sbjct: 947  AALEQERQELRLE-KERINATALRVKLRAEEVESMSKVASEKYEEGER-ALREAQQVQAE 1004

Query: 64   TEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIP 112
             +  ++ + Q+ +     R R Q  HM    +   ++   L +   ++P
Sbjct: 1005 QQARLQAVQQQQE-----RLRKQEQHMHQEHLSLAQQRLQLDRARQDLP 1048


>gi|110349756 zygin 2 isoform 2 [Homo sapiens]
          Length = 380

 Score = 31.6 bits (70), Expect = 0.48
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
           M +  + + KRS  G  ++R++ +S  E    + +L +   A  EY  S+ +   L+++D
Sbjct: 193 MLSQEIQTLKRSSTGSYEERVKRLSVSE---LNEILEEIETAIKEY--SEELVQQLALRD 247

Query: 61  EIETEEIIKDIF 72
           E+E E+ +K+ F
Sbjct: 248 ELEFEKEVKNSF 259


>gi|110349754 zygin 2 isoform 1 [Homo sapiens]
          Length = 353

 Score = 31.6 bits (70), Expect = 0.48
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
           M +  + + KRS  G  ++R++ +S  E    + +L +   A  EY  S+ +   L+++D
Sbjct: 193 MLSQEIQTLKRSSTGSYEERVKRLSVSE---LNEILEEIETAIKEY--SEELVQQLALRD 247

Query: 61  EIETEEIIKDIF 72
           E+E E+ +K+ F
Sbjct: 248 ELEFEKEVKNSF 259


>gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10
           isoform a [Homo sapiens]
          Length = 1090

 Score = 31.2 bits (69), Expect = 0.63
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 81  PRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQP--GEGDVREEALSTGGLDLIFMPGLG 138
           PR+R QS  + +V +++P    + P T + +     G G+VR E +     +++  PG G
Sbjct: 880 PRHRQQS--VLLVPMDTPGIKIIRPLTVYGLEDAPGGHGEVRFEHVRVPKENMVLGPGRG 937

Query: 139 FDKHGNRLGRGK 150
           F+    RLG G+
Sbjct: 938 FEIAQGRLGPGR 949


>gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isoform
           b [Homo sapiens]
          Length = 1059

 Score = 31.2 bits (69), Expect = 0.63
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 81  PRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQP--GEGDVREEALSTGGLDLIFMPGLG 138
           PR+R QS  + +V +++P    + P T + +     G G+VR E +     +++  PG G
Sbjct: 849 PRHRQQS--VLLVPMDTPGIKIIRPLTVYGLEDAPGGHGEVRFEHVRVPKENMVLGPGRG 906

Query: 139 FDKHGNRLGRGK 150
           F+    RLG G+
Sbjct: 907 FEIAQGRLGPGR 918


>gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo
           sapiens]
          Length = 497

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 4/93 (4%)

Query: 48  KSKRISIFLSMQDEIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIES----PEEISL 103
           K+    + L + +   T+E  K I Q+   C +  Y F  +    +  ES     +++S 
Sbjct: 140 KTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSY 199

Query: 104 LPKTSWNIPQPGEGDVREEALSTGGLDLIFMPG 136
             + +     PG GD+     ++G LD     G
Sbjct: 200 SGENTEAWYPPGHGDIYASFYNSGLLDTFIGEG 232


>gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo
           sapiens]
          Length = 508

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 4/93 (4%)

Query: 48  KSKRISIFLSMQDEIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIES----PEEISL 103
           K+    + L + +   T+E  K I Q+   C +  Y F  +    +  ES     +++S 
Sbjct: 151 KTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSY 210

Query: 104 LPKTSWNIPQPGEGDVREEALSTGGLDLIFMPG 136
             + +     PG GD+     ++G LD     G
Sbjct: 211 SGENTEAWYPPGHGDIYASFYNSGLLDTFIGEG 243


>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
          Length = 1668

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 27  EERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIFQRGKICFIPRYRFQ 86
           EE +RQ+ VL Q  ++H  ++  K  ++    Q     ++  +D+ Q       P YR++
Sbjct: 930 EEMMRQNHVLKQPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQ-------PTYRYE 982

Query: 87  SN 88
           S+
Sbjct: 983 SS 984


>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
          Length = 1748

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 27   EERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIFQRGKICFIPRYRFQ 86
            EE +RQ+ VL Q  ++H  ++  K  ++    Q     ++  +D+ Q       P YR++
Sbjct: 1010 EEMMRQNHVLKQPAVSHPGHRPDKEPNLTYEPQLPYVEKQASRDLEQ-------PTYRYE 1062

Query: 87   SN 88
            S+
Sbjct: 1063 SS 1064


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
           X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 28.1 bits (61), Expect = 5.3
 Identities = 30/155 (19%), Positives = 63/155 (40%), Gaps = 7/155 (4%)

Query: 16  ELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIFQRG 75
           E+K + R ++ +E + Q+   + K++      ++K  +  L  + E + E + +    + 
Sbjct: 226 EVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQT---KA 282

Query: 76  KICFIPRYRFQSNHMDMVRIES---PEEISLLPKTS-WNIPQPGEGDVREEALSTGGLDL 131
           +   +     + N + + + E+   P E++ +  T+   I    +    EE +S      
Sbjct: 283 ETHILAEKETEINRVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQS 342

Query: 132 IFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEV 166
              PG   D  GN  G  +      +K C Q Q V
Sbjct: 343 EARPGATVDARGNPNGMSREVAGVDMKSCAQSQAV 377


>gi|76496497 artemis protein isoform a [Homo sapiens]
          Length = 692

 Score = 27.7 bits (60), Expect = 7.0
 Identities = 11/28 (39%), Positives = 18/28 (64%)

Query: 81  PRYRFQSNHMDMVRIESPEEISLLPKTS 108
           P+YRF    +  + IE+P +ISL+ + S
Sbjct: 73  PKYRFWKKRIISIEIETPTQISLVDEAS 100


>gi|44955929 calmodulin regulated spectrin-associated protein 1-like 1
            [Homo sapiens]
          Length = 1478

 Score = 27.7 bits (60), Expect = 7.0
 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 17/114 (14%)

Query: 10   KRSLRGEL---KQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETE- 65
            K+ L  E+   K+  R  + EER ++    +++     EY + K++ +   M   I+   
Sbjct: 1186 KQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRP 1245

Query: 66   EIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPE-EISLLPKTSWNIPQPGEGD 118
            +++K   QR K          S H D   IESP+  I   P +S ++     GD
Sbjct: 1246 QVVKQKKQRPK----------SIHRD--HIESPKTPIKGPPVSSLSLASLNTGD 1287


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 27.3 bits (59), Expect = 9.1
 Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 5/96 (5%)

Query: 61  EIETEEIIKDIFQRGKICFIP-----RYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPG 115
           E+ET    K+I  RG  C  P        F +N MD++  ++  E + +    W +   G
Sbjct: 72  EVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSG 131

Query: 116 EGDVREEALSTGGLDLIFMPGLGFDKHGNRLGRGKG 151
              V      +G      +P +    H   L RG G
Sbjct: 132 LDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDG 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,482,065
Number of Sequences: 37866
Number of extensions: 349082
Number of successful extensions: 809
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 807
Number of HSP's gapped (non-prelim): 14
length of query: 203
length of database: 18,247,518
effective HSP length: 97
effective length of query: 106
effective length of database: 14,574,516
effective search space: 1544898696
effective search space used: 1544898696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.