Guide to the Human Genome
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Name: MTHFS Sequence: fasta or formatted (203aa) NCBI GI: 5453746
Description:

5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)

Referenced in:

Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.4         13           4
 C cysteine            1.5          3           1
 D aspartate           4.9         10           1
 E glutamate           9.4         19           2
 F phenylalanine       3.4          7           1
 G glycine             5.9         12           2
 H histidine           2.0          4           1
 I isoleucine          6.9         14           2
 K lysine              6.9         14           1
 L leucine             9.4         19           2
 M methionine          3.4          7           1
 N asparagine          2.5          5           1
 P proline             3.9          8           1
 Q glutamine           5.9         12           1
 R arginine            7.9         16           1
 S serine              8.4         17           2
 T threonine           2.5          5           1
 V valine              4.9         10           1
 W tryptophan          0.5          1           1
 Y tyrosine            3.4          7           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   5,10-methenyltetrahydrofolate synthetase (5-formyltet... 
FBF1                  0.019   Fas (TNFRSF6) binding factor 1 
FEZ2                  0.019   zygin 2 isoform 2 
FEZ2                  0.019   zygin 2 isoform 1 
ACAD10                0.016   acyl-Coenzyme A dehydrogenase family, member 10 iso...
ACAD10                0.016   acyl-Coenzyme A dehydrogenase family, member 10 isof...
UGP2                  0.011   UDP-glucose pyrophosphorylase 2 isoform b 
UGP2                  0.011   UDP-glucose pyrophosphorylase 2 isoform a 
TJP1                  0.011   tight junction protein 1 isoform b 
TJP1                  0.011   tight junction protein 1 isoform a 
LOC100292655          0.008   PREDICTED: similar to armadillo repeat containing, ...
DCLRE1C               0.008   artemis protein isoform a 
CAMSAP1L1             0.008   calmodulin regulated spectrin-associated protein 1-l...
DDX5                  0.005   DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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