BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|53759122 adenomatous polyposis coli [Homo sapiens] (2843 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189011568 adenomatous polyposis coli [Homo sapiens] 5614 0.0 gi|189011566 adenomatous polyposis coli [Homo sapiens] 5614 0.0 gi|53759122 adenomatous polyposis coli [Homo sapiens] 5614 0.0 gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 873 0.0 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 95 1e-18 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 94 1e-18 gi|91982772 mucin 17 [Homo sapiens] 90 3e-17 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 73 4e-12 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 71 1e-11 gi|161016767 mucin 21 [Homo sapiens] 71 2e-11 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 70 4e-11 gi|28559039 mediator complex subunit 1 [Homo sapiens] 69 9e-11 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 67 2e-10 gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 67 3e-10 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 66 6e-10 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 66 6e-10 gi|151301154 mucin 6, gastric [Homo sapiens] 65 7e-10 gi|50083281 KIAA1853 protein [Homo sapiens] 65 1e-09 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 62 6e-09 gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 62 8e-09 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 62 1e-08 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 61 2e-08 gi|149944526 additional sex combs like 3 [Homo sapiens] 61 2e-08 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 59 5e-08 gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 58 2e-07 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 3e-07 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 56 6e-07 gi|120953251 neuron navigator 3 [Homo sapiens] 56 6e-07 gi|83367077 mucin 16 [Homo sapiens] 55 8e-07 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 55 8e-07 >gi|189011568 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 5614 bits (14564), Expect = 0.0 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%) Query: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM Sbjct: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 Query: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR Sbjct: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 Query: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL Sbjct: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 Query: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT Sbjct: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 Query: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA Sbjct: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 Query: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL Sbjct: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 Query: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC Sbjct: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 Query: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ Sbjct: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 Query: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL Sbjct: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 Query: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT Sbjct: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 Query: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN Sbjct: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 Query: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM Sbjct: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 Query: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS Sbjct: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 Query: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS Sbjct: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 Query: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS Sbjct: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 Query: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS Sbjct: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 Query: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE Sbjct: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 DSTESSGTQSPKRHSGSYLVTSV Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 >gi|189011566 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 5614 bits (14564), Expect = 0.0 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%) Query: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM Sbjct: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 Query: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR Sbjct: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 Query: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL Sbjct: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 Query: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT Sbjct: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 Query: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA Sbjct: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 Query: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL Sbjct: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 Query: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC Sbjct: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 Query: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ Sbjct: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 Query: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL Sbjct: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 Query: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT Sbjct: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 Query: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN Sbjct: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 Query: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM Sbjct: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 Query: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS Sbjct: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 Query: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS Sbjct: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 Query: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS Sbjct: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 Query: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS Sbjct: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 Query: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE Sbjct: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 DSTESSGTQSPKRHSGSYLVTSV Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 >gi|53759122 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 5614 bits (14564), Expect = 0.0 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%) Query: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM Sbjct: 1 MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60 Query: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR Sbjct: 61 ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120 Query: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL Sbjct: 121 RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180 Query: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT Sbjct: 181 QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240 Query: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA Sbjct: 241 EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300 Query: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL Sbjct: 301 PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360 Query: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC Sbjct: 361 HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420 Query: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ Sbjct: 421 WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480 Query: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL Sbjct: 481 VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540 Query: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT Sbjct: 541 QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600 Query: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN Sbjct: 601 ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660 Query: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM Sbjct: 661 CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720 Query: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS Sbjct: 721 GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780 Query: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS Sbjct: 781 PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840 Query: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS Sbjct: 841 LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900 Query: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS Sbjct: 901 QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960 Query: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE Sbjct: 961 NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020 Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080 Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140 Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200 Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440 Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500 Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560 Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800 Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860 Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920 Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980 Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040 Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100 Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160 Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220 Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280 Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340 Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520 Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580 Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 DSTESSGTQSPKRHSGSYLVTSV Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 >gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] Length = 2303 Score = 873 bits (2255), Expect = 0.0 Identities = 498/1007 (49%), Positives = 661/1007 (65%), Gaps = 93/1007 (9%) Query: 2 AAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEA-- 59 + A Y+QL++QVEALK ENS+LRQEL DNS+HL+KLETE S MKEVLK LQG +E EA Sbjct: 4 SVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARV 63 Query: 60 MASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFP 119 + SSGQ ++LE+LK L +D ++ +K + + ++R+ E SPV Sbjct: 64 LVSSGQTEVLEQLKALQMDITSLYNLKFQPP-------TLGPEPAARTPEGSPVHGSGPS 116 Query: 120 RRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTEN-F 178 + F SR + LEEL++ER LL +++KEEKEK WYY+QLQ L+KR+D LP E F Sbjct: 117 KDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQF 176 Query: 179 SLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQ 238 S+Q D+ R+QLE+EA+ IR MEE+ GT +M +RAQ R +R++QI+K++L Sbjct: 177 SMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLE-------- 228 Query: 239 ATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTH 298 + D +Q E Q + + + +D + + + + Sbjct: 229 ---------------AQDRVQQTEPQALLAVK----------SVPVDEDPETEVPTHPED 263 Query: 299 SAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQ 358 P+ S KVE+V+ LLSML T D++D +RTLLAMSSS +SC++MR+SGCLPLL+Q Sbjct: 264 GTPQPGNS----KVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQ 319 Query: 359 LLHGNDKDS---VLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRA 415 +LHG + + + G+K+AR RA+AALHNI+ SQPD R+E+RVLH+LEQIRA Sbjct: 320 ILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRA 379 Query: 416 YCETCWEWQEAHEPGMDQD-KNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQA 474 YCETCW+W +A + G + P P+E QIC A C +MKLSFDEE+R AMNELGGLQA Sbjct: 380 YCETCWDWLQARDGGPEGGGAGSAPIPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQA 439 Query: 475 IAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK 534 +AELLQVD EM+ +T D ++ LRRYAGM LTNLTFGDVANKATLC+ +GCM A+VAQL Sbjct: 440 VAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLA 499 Query: 535 SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWN 594 S+SE+L QV++S+LRNLSWRAD+NSKK LRE GSV AL++C L KESTLKSVLSALWN Sbjct: 500 SDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWN 559 Query: 595 LSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQ 654 LSAH TENKA IC VDGAL FLV TLTY+ Q+N+LAIIESGGGILRNVSSL+AT ED+RQ Sbjct: 560 LSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLVATREDYRQ 619 Query: 655 ILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSK 714 +LR++NCLQTLLQHL SHSLTIVSNACGTLWNLSAR+ +DQE LWD+GAV ML+NL+HSK Sbjct: 620 VLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSK 679 Query: 715 HKMIAMGSAAALRNLMANRPAKYK-DANIMSPGSSLPSLHVRKQKALEAELDAQHLSETF 773 HKMIAMGSAAALRNL+A+RPAK++ A +SPGS +PSL+VRKQ+ALEAELDA+HL++ Sbjct: 680 HKMIAMGSAAALRNLLAHRPAKHQAAATAVSPGSCVPSLYVRKQRALEAELDARHLAQAL 739 Query: 774 DNIDNLSPKASHRSKQ------RHKQSLYGDYVFDTNRHDDNRSDN-----FNTG----- 817 ++++ P A+ + + RH L DY D+ DD+ + + TG Sbjct: 740 EHLEKQGPPAAEAATKKPLPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASP 799 Query: 818 ---NMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSS 874 ++ + SP+L L + +R +EKD S E ++ Sbjct: 800 AALSLFLGSPFLQGQALARTPPTRRG--GKEAEKDTSGE----------------AAVAA 841 Query: 875 KRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNT 934 K +++ A+I +++E++SA+HTS +D S S+ + + S Sbjct: 842 KAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEG- 900 Query: 935 YNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKP 981 + E +R + K + SNDSLNS S+SDGY R M P Sbjct: 901 ---GRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPREHMLP 944 Score = 210 bits (534), Expect = 2e-53 Identities = 168/463 (36%), Positives = 229/463 (49%), Gaps = 67/463 (14%) Query: 1222 SSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLS 1281 S A++Q L A S P+K A +S + + +Q ++ P+ SRCSSLSSLS Sbjct: 1022 SPGARKQAWL---PADHLSKVPEKLAAAPLS-VASKALQKLAAQEGPLSLSRCSSLSSLS 1077 Query: 1282 SAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAE-DPVSEVPAVSQHPRTKSS--RLQ 1338 SA G ++ D ++ E E+ G AE D P + P + R + Sbjct: 1078 SA----GRPGPSEGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNR 1133 Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFES 1398 G L E A TP S E+YVQETPL+ SRC+SVSSL SFES Sbjct: 1134 GRGLGVEDA--------------------TPSSSSENYVQETPLVLSRCSSVSSLGSFES 1173 Query: 1399 RSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP--PPPQTAQTKREVPKNK 1456 SIASS+ SEPCSG SG ISPS+LPDSPGQTMPPSRSKTPP P PQ P Sbjct: 1174 PSIASSIPSEPCSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQG-------PPEA 1226 Query: 1457 APTAEKRESGPKQAAVNAAVQRVQVLP---DADTLLHFATESTPDGFSCSSSLSALSLDE 1513 + + ES K+ A + LP DA + + F E + FSC+SSLSAL+L E Sbjct: 1227 TQFSLQWESYVKRFLDIADCRERCRLPSELDAGS-VRFTVEKPDENFSCASSLSALALHE 1285 Query: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573 ++Q+DVELR++P G + + +E+ T + + D ++E Sbjct: 1286 HYVQQDVELRLLPSACPERGGGAGGAGLHFAGHRRREEGPAPTGSRPR----GAADQELE 1341 Query: 1574 ILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFT 1633 +L EC+ +A+P + + AS L P R+ +PVY L+P+ Q Sbjct: 1342 LLRECLGAAVPARLRK-------VASALVP--GRRALPVPVYMLVPAPAPAQ-------- 1384 Query: 1634 PGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVR 1676 +D EGTP+NFS+A SLSD T++ PP + G R Sbjct: 1385 --EDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGR 1425 Score = 188 bits (477), Expect = 7e-47 Identities = 273/998 (27%), Positives = 410/998 (41%), Gaps = 208/998 (20%) Query: 1825 DKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKA 1884 DK + R RG A S TP E YCF NDS Sbjct: 1478 DKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDS----------------------- 1514 Query: 1885 KENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRG 1944 E + A +H +T AI + R +P+ +K++ P + Sbjct: 1515 DEEPPAAAPTPTH----------RRTSAIPRA-FTRERPQG--RKEAPAPSKAAPAAPPP 1561 Query: 1945 AATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQA 2004 A T L + TP C+S +SS SSLS E EP +EPP +P Sbjct: 1562 ARTQPSL---IADETPPCYSLSSSASSLS---------EPEP---SEPPAVHPRGREPAV 1606 Query: 2005 SGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKP-SRLKGDNEKH 2063 + +D R+SS S + + +LLQ CISSA+P+++ P S L+ + Sbjct: 1607 T---------KDPGPGGGRDSSPSPRAAE---ELLQRCISSALPRRRPPVSGLR----RR 1650 Query: 2064 SPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAAC 2123 PR L E ++ + + D ++ +W+AIQEGANSIV+ LHQAAAA Sbjct: 1651 KPRATR--LDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAA-- 1706 Query: 2124 LSRQASSDSDSILSLKSGISLGS----PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETK 2179 +R+ASS+SDSILS SG+S+GS P H Q E S + P EK + Sbjct: 1707 -TREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRP------EKRGAASV 1759 Query: 2180 KIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPG---- 2235 K + G +K + Q +P++ RGRT+I++P Sbjct: 1760 KTSGSPRSPAGPEK-----------------PRGTQKTTPGVPAVLRGRTVIYVPSPAPR 1802 Query: 2236 --VRNSSSSTSPVSKKGPP-LKTPA--SKSPSEGQTATTS-PRGAKPSVKSELSPVARQT 2289 + + + K PP L PA +K PS GQ + S R AK S + LS R Sbjct: 1803 AQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSA 1862 Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 + +K PS S S+ S PA QPL R R ++ + P S +P+T Sbjct: 1863 TPPARLAKTPSSSSSQTS----PASQPLPRK-----RPPVTQAAGALPGPG-ASPVPKTP 1912 Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409 + + + + + SP R Q ++ G A ++P E +G G G Sbjct: 1913 ARTLLAKQHK-----TQRSPVRIPFMQRPARR-GPPPLARAVP--EPGPRGRAGTEAGPG 1964 Query: 2410 A-NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPS 2468 A ++ L R++S SSGSES S+R RQ TFIKE SP LRR+ E +S ES + + Sbjct: 1965 ARGGRLGLVRVASALSSGSES--SDRSGFRRQLTFIKE--SPGLRRRRSELSSAESAASA 2020 Query: 2469 SRPASPTRSQAQTPVL---SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR 2525 + ASP R + P + S ++ + R+ PP P+ RPA+ Sbjct: 2021 PQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPA--RQRPPAARPS---PGERPAR- 2074 Query: 2526 HDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585 R+ SESPSRLP+ R+ + E K +SLP +S RR + AS++++ ++ Sbjct: 2075 ----RTTSESPSRLPV-RAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAARRSS 2129 Query: 2586 SEDEKHVNSISGTKQSKENQVSAKG-TWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644 + + + +V+A G TWR+I++ + ++ ++ G+ + Sbjct: 2130 DGEPRPL-----------PRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDA- 2177 Query: 2645 YQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNT--PPVIDSVSEKANPNIKDSKDNQA 2702 P KT D V+ E+ S SP+ T PP + + + + A Sbjct: 2178 -PAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGGQLSLLGSDVDGPSLA 2236 Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF 2762 K + S P GL + F Sbjct: 2237 KAPI---SAPFVHEGLGVAVGGF------------------------------------- 2256 Query: 2763 SSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800 +S+H SPS +ARV PFNY PSP +A + SA Sbjct: 2257 ---PASRHGSPSR--SARVPPFNYVPSPMVVAATTDSA 2289 Score = 36.2 bits (82), Expect = 0.47 Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 48/176 (27%) Query: 1432 PPSRSKTPPPPPQTAQTKREVPK---NKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTL 1488 PP+ + TP T + +P+ + P K P +AA A P A T Sbjct: 1518 PPAAAPTP-----THRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAP-------PPARTQ 1565 Query: 1489 LHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND---NGNETESEQPKES 1545 + TP +S SSS S+LS EP V R P D G S P+ + Sbjct: 1566 PSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAA 1625 Query: 1546 NENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTK----SSRKAKKPAQT 1597 E+L+ CI SA+P + S + +KP T Sbjct: 1626 E--------------------------ELLQRCISSALPRRRPPVSGLRRRKPRAT 1655 Score = 35.4 bits (80), Expect = 0.81 Identities = 55/244 (22%), Positives = 90/244 (36%), Gaps = 44/244 (18%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQ-NQLHPSS 1235 ID ++ + + +S SFS S GQ + E + S P + ++ HP Sbjct: 854 IDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEGGRREAGSRAHPLL 913 Query: 1236 AQSRSGQPQKAATCKVS--SINQETIQT-YCVEDTPICFSRCSSLSSLSSAEDEIGCNQ- 1291 KAA +S S+N + YC + + L++L+S ++ C Q Sbjct: 914 R-------LKAAHASLSNDSLNSGSASDGYCPREHML----PCPLAALASRREDPRCGQP 962 Query: 1292 ----------------TTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSS 1335 +EA SA+ ++ T VP + R + Sbjct: 963 RPSRLDLDLPGCQAEPPAREATSADA--------RVRTIKLSPTYQHVPLLEGASRAGAE 1014 Query: 1336 RLQGSSLSSESARHKAVEFSSGAKSPSKSGAQ----TPKSPPEHYVQETPLMFSRCTSVS 1391 L G +S + + + +K P K A K+ + QE PL SRC+S+S Sbjct: 1015 PLAGPGISPGARKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLS 1074 Query: 1392 SLDS 1395 SL S Sbjct: 1075 SLSS 1078 Score = 34.7 bits (78), Expect = 1.4 Identities = 49/203 (24%), Positives = 87/203 (42%), Gaps = 45/203 (22%) Query: 1871 DVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAK---QPINRGQPKPIL 1927 D+DL +AE A+E ++A+V + +L+ Q + ++ +P+ P Sbjct: 968 DLDLPGCQAE-PPAREATSADARVRT-IKLSPTYQHVPLLEGASRAGAEPLAGPGISPGA 1025 Query: 1928 QKQSTFPQSS-KDIPDRGAAT-----DEKLQNFAIENTPVCFSHNSSLSSLSDI------ 1975 +KQ+ P +P++ AA + LQ A + P+ S SSLSSLS Sbjct: 1026 RKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLSSLSSAGRPGPS 1085 Query: 1976 ---DQENNNKENEPIKETEPPDSQ--------GEPSKP-----------------QASGY 2007 D ++++ E ++E P +++ G S P A+ Sbjct: 1086 EGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVEDATPS 1145 Query: 2008 APKSFHVEDTPVCFSRNSSLSSL 2030 + +V++TP+ SR SS+SSL Sbjct: 1146 SSSENYVQETPLVLSRCSSVSSL 1168 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 94.7 bits (234), Expect = 1e-18 Identities = 162/778 (20%), Positives = 287/778 (36%), Gaps = 37/778 (4%) Query: 2063 HSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAA 2122 +S N G G D D + DS G S DS + D ++S SS ++ + Sbjct: 523 NSDSNGNGNNGND------DNDKSDSGKGKS-DSSDSDSSDSSNSSDSSDSSDSDSSDSN 575 Query: 2123 CLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE 2182 S SSDSDS S S S S + D + +S+ + S E+ + Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635 Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSS-S 2241 S+SK S +S S ++ S + +SS S Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695 Query: 2242 STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSR 2301 S S S S S+ + +S + S S S + +S SS + Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755 Query: 2302 SGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGS 2361 S S DS+ S + S NS + S + S SS S+ S+ SS S Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS---NSSDSSNSSDSSDS 812 Query: 2362 GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSS 2421 S + N + + S ++ S S+S+ + +N + ++ + S S Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872 Query: 2422 TKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT 2481 + +S SD S+ +S+ ++ + + S S S S S S++ Sbjct: 873 SSNSSDSSDSSDS----NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928 Query: 2482 PVLSPSLPDMSLSTHSSVQAGGWRKLPP-NLSPTIEYNDGRPAKRHDIARSHSESPSRLP 2540 + + D S S+ SS + N S + +D + D + S + S S Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988 Query: 2541 INRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQ 2600 + S + S +SS S SS S SS SS+ + S D + + S + Sbjct: 989 SDSSDSSDSSDSSNSSD----------SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038 Query: 2601 SKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVR 2660 S ++ S+ + N ++S+ + SS +++ ++S + S Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS---D 1095 Query: 2661 IEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLEN 2720 D ++ S S + ++ DS + + + DS D+ N + S + + Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155 Query: 2721 RLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS-------IVERTPFSSSSSSKHSSP 2773 +S D+ D + +N S++++SS + + S SS S SS Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215 Query: 2774 SGTVAARVTPFNYNPSPRKS-SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830 S + + + S S S+DS+ + S + ++++ DS +DS + S +QS Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273 Score = 89.7 bits (221), Expect = 4e-17 Identities = 139/664 (20%), Positives = 247/664 (37%), Gaps = 49/664 (7%) Query: 765 DAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNR--SDNFNTGNMTVL 822 D+ S++ D+ D+ S + S S +++ DN SD+ N+ N + Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668 Query: 823 SPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQIST 882 S +++ SSS S S DSS S N ++++ +S S Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDS-----------SNSSESSDSSDSSDSDSSDSSD 717 Query: 883 TAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSEN 942 ++ + + ++ +S SS S+ +D N+ S ++ + +++ + S++ Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDS----SDSSNSSDSSDSSDSSNSSDSSDSSDS 773 Query: 943 SNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPA 1002 S+ + S + +S+DS +S +SSD S S S+ S S + Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 1003 DLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQ 1062 D ++ S++ D +DG N S S +S S S N D Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRS--DSSNSSDSSDSSDSSNS---------SDSSDS 882 Query: 1063 SEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGIN 1122 S+ +S N S + S D S S +N S+++ SN N Sbjct: 883 SDSNESSNSSDSSDSSNSSDSD---------SSDSSNSSDSSDSSNSSDSSE-SSNSSDN 932 Query: 1123 QNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLK 1182 N S S D + +N S+ + + + + S ++ D S Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD-----SSD 987 Query: 1183 YATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQ 1242 + SS S S SS S ++ +SS + S+ SSN+ + SS S S Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047 Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTL 1302 ++ SS + ++ + D+ S S S S + D + ++ +DS+++ Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDS----SDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103 Query: 1303 QIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPS 1362 ++ + + + D + + + SS SS SS+S+ SS + S Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163 Query: 1363 KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSD 1422 S + S + S +S SS S S S SS S+ S S SD Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSD 1221 Query: 1423 LPDS 1426 DS Sbjct: 1222 SSDS 1225 Score = 89.4 bits (220), Expect = 5e-17 Identities = 220/1170 (18%), Positives = 405/1170 (34%), Gaps = 90/1170 (7%) Query: 1662 IESPPNELAAGEGVRGGAQSGEFEKRDTIPT-EGRSTDEAQGGKTSSVTIPELDDNKAEE 1720 I S N E G + + D P+ G DE +G DD E Sbjct: 217 INSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSG---------DDEDEEA 267 Query: 1721 GDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP 1780 G+ NS +G+ H + +S ++ +K D + K+ P Sbjct: 268 GNGKDSSNNSKGQEGQDHGK-------EDDHDSSIGQNSDSKEYYDPEGKED-------P 313 Query: 1781 QNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAF 1840 N + K+ ++ + + +D++K N + + +V N +E G Sbjct: 314 HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGK--- 370 Query: 1841 DSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTEL 1900 S I+G P +RN +++E + + KE+K + + Sbjct: 371 -SQDKGIEIKG-PSSGNRN--------------ITKEVGKGNEGKEDKGQHGMILGKGNV 414 Query: 1901 TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTP 1960 + + N + P + +P + +T S+ D D D+ +Q + P Sbjct: 415 KTQGEVVN-----IEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG----DDP 465 Query: 1961 VCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVC 2020 NSS S + D + + N + +S + SK +G K +D+ Sbjct: 466 -----NSSDESNGNDDANSESDNNSSSRGDASYNS--DESKDNGNGSDSKGAEDDDSDST 518 Query: 2021 FSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDL 2080 N+S S+ + ++ +D + S K D+ S + + Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577 Query: 2081 KDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKS 2140 D DS+ S DS++ D + ++S SS ++ + S+ SS S+S S Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS--- 634 Query: 2141 GISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200 D + K +S+ S+ + S S Sbjct: 635 ------------DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682 Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260 S+S S +++ S S NS+SS S S + S Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742 Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320 S+ ++ S + S S S +S SS + S S DS S + Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSS----DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798 Query: 2321 IQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTK 2380 S NS + S + S SS S+ S+ SS S S +S S + + Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSN----SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854 Query: 2381 QTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQ 2440 + S +++S S+S+ + ++ + + + S SS S+ S+SD S+ Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914 Query: 2441 STFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQ 2500 S + S + S S +S + S S S + S + S S+ S+ Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974 Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPR 2560 + S + + +D + + S+S + S +SS Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034 Query: 2561 VSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEF 2620 S+ S SS S SS+SS + S D + S + S ++ S++ + N Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094 Query: 2621 SPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTP 2680 ++S+ + SS +++ ++S + S D ++ S S + ++ Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154 Query: 2681 PVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP 2740 DS + + DS D+ N + S + + +S D+ D + Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214 Query: 2741 GQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800 ++ S++++SS + SS SS S + + ++ + S++DS Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD------SSDSSDSTSDSNDE 1268 Query: 2801 RPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830 SQ + N N DS +DS S S Sbjct: 1269 SDSQSKSG-NGNNNGSDSDSDSEGSDSNHS 1297 Score = 88.6 bits (218), Expect = 8e-17 Identities = 160/747 (21%), Positives = 283/747 (37%), Gaps = 39/747 (5%) Query: 2095 DSENFDWKAIQ-EGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPD 2153 DS +FD K++Q + NS S + A+S+SD+ S + S S D Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNG--------NDDANSESDNNSSSRGDASYNS------D 496 Query: 2154 QEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQM 2213 + + + ST +T +S G G KS +GK +S+S S Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSS 555 Query: 2214 KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRG 2273 ++ S + +SS S S S + +S S + ++ +S Sbjct: 556 DSSNSSDSSDSSDSDSS----DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611 Query: 2274 AKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333 + + SS + S+S S DS S + S S NS + Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS----SDSSNSSNSSD 667 Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 + S + S SS S+ S+ SS S S +S S + + + S + SS Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSE--SDRSERPVLVRQSTFIKEAPSPT 2451 S ++S + N+ + ++ + S+ SS S SD S+ S + S Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787 Query: 2452 LRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNL 2511 + S S S S SS + + S + S + D S S+ SS + + Sbjct: 788 SSNSSDSSDSSNS-SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS--SDS 844 Query: 2512 SPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSS 2571 S + + +D + R D + S S S N S + S SS+ S SS+ Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD-----SSN 899 Query: 2572 SILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVS 2631 S S SS+SS + S D + + S + S +N S+ + + +NS+ + S Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959 Query: 2632 SGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691 S ++N ++S + S + D D ++ S S + N+ DS + Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDS----SDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015 Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSET 2751 N DS ++ N + S + + +S D+ + + ++ S++ Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075 Query: 2752 NESS-IVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVN 2810 ++SS E + S SS+S SS S + + + S S + ++S + + Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135 Query: 2811 NNTKKRDSKTDSTESSGTQSPKRHSGS 2837 +++ +DS+ESS + S S Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDS 1162 Score = 81.6 bits (200), Expect = 1e-14 Identities = 141/775 (18%), Positives = 286/775 (36%), Gaps = 27/775 (3%) Query: 805 RHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYH 864 + D + SD+ ++ N + S ++ S+SSS DSS S+ S + + + Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSSD 603 Query: 865 PATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQE--DRSSGSTTELHCVTDERNAL 922 + + + S S + + +K + S + + D +S +++ +D N+ Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663 Query: 923 RRSSAAHTHSNTYNFTKSENSNRTCSMPYA---KLEYKRSSNDSLNSVSSSDGYGKRGQM 979 S ++ + ++ + + S++SN + S + S+DS +S SS Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723 Query: 980 KPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSD--EQLN 1037 S S S D S S +D + +S++ D +D + + S SD + N Sbjct: 724 SDSDSSNSSD--SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781 Query: 1038 SGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQE 1097 S + S N + D S+ S + S + + + + Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841 Query: 1098 CVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEE 1157 S S G++ +NR S++ + + S D D +N S S+ Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD----- 896 Query: 1158 RPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSEN 1217 +N S + + + D +++ S + S S S+S SS + S SS++ Sbjct: 897 -SSNSSDSDSSDSSNSSDSSD-----SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950 Query: 1218 TSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL 1277 +++ S+ + S+ S S ++ SS + ++ + D+ S S Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS----SNSSDS 1006 Query: 1278 SSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRL 1337 S S + D + ++ +DS+N+ ++ + + + D + + + SS Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066 Query: 1338 QGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFE 1397 SS SS+S+ SS + S S + S + S +S SS S Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126 Query: 1398 SRSIASSVQSEPCSGMVSGIIS-PSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNK 1456 S S SS S+ + S S SD DS + S + + + + Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186 Query: 1457 APTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFI 1516 + +++ +S + +++ + +++S+ S SS S+ S D Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246 Query: 1517 QKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571 + ++ + + ES+ +S ++ DSE + S DD Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 74.7 bits (182), Expect = 1e-12 Identities = 149/751 (19%), Positives = 271/751 (36%), Gaps = 85/751 (11%) Query: 827 NTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQ 886 N+ +P + S+ D+ + S E I T G S +G++I ++ Sbjct: 328 NSAGIPEDNGSQRIEDTQKLNHRESKRVENRI---TKESETHAVGKSQDKGIEIKGPSSG 384 Query: 887 IAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFT----KSEN 942 + +EV + +ED+ + + T N KSE Sbjct: 385 NRNITKEVGKGNEGKEDKG------------QHGMILGKGNVKTQGEVVNIEGPGQKSEP 432 Query: 943 SNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYP- 1001 N+ + + S S+SDGY +SY DD+S G P Sbjct: 433 GNKV-------------GHSNTGSDSNSDGY----------DSYDFDDKSM---QGDDPN 466 Query: 1002 -ADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEI 1060 +D ++ AN DN+ +Y+ SDE ++G S S+ ED+ Sbjct: 467 SSDESNGNDDANSESDNNSSSRGDASYN---SDESKDNGNGSDSKGA---------EDD- 513 Query: 1061 KQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHG 1120 S+ N S + DD K G+ + S +N S+++ + Sbjct: 514 -DSDSTSDTNNSDSNGNGNNGNDDND-KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571 Query: 1121 INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYS 1180 + N S + D D ++ S+ S + + + ++ S ++ D D S Sbjct: 572 SDSNSSS----DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627 Query: 1181 LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRS 1240 S S S SKS S S+ ++ +S + S+ SSN+ + SS S S Sbjct: 628 -------KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680 Query: 1241 GQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSAN 1300 ++ SS + + ++ D+ S SS SS S++ D N ++ +DS+N Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN-SSDSSDSSN 739 Query: 1301 TLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS 1360 + ++ + + + D + + SS SS SS+S SS + + Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799 Query: 1361 PSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP 1420 S S + S ++ S +S SS S S S SS S+ G S + Sbjct: 800 SSDSSNSSDSSDSSD-SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858 Query: 1421 SDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQ 1480 SD +S + S + + + + + ++ +S ++ ++ Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918 Query: 1481 VLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESE 1540 D+ ++ S+ + S SS S+ S D + +D+ N ++S Sbjct: 919 NSSDSSE----SSNSSDNSNSSDSSNSSDSSDSSDSSNSSD-----SSNSSDSSNSSDSS 969 Query: 1541 QPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571 S+ + + + DS D D SD D Sbjct: 970 DSNSSDSSDSSNSSDSSDS-SDSSDSSDSSD 999 Score = 71.6 bits (174), Expect = 1e-11 Identities = 133/659 (20%), Positives = 244/659 (37%), Gaps = 65/659 (9%) Query: 765 DAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSP 824 D+ + SE+ D+ D+ +S S + S D + + + SD+ N+ + + S Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD-----SSNSSDSSDSSNSSDSSDSSD 748 Query: 825 YLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTA 884 N++ SS S S DSS S N + + SS +++ Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808 Query: 885 AQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSN 944 + + + + ++S SS S+ D N SS + S++ + + S++SN Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSS-------DSSN----SSDSSDSSDSSDGSDSDSSN 857 Query: 945 RTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADL 1004 R+ S +S+DS +S SS+ + S S D S +D Sbjct: 858 RSDSS---------NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908 Query: 1005 AHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSE 1064 ++ S++ + +D S E NS S S + + D S+ Sbjct: 909 SNSSDSSDSSNSSD-------------SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955 Query: 1065 QRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQN 1124 S + S + ++S+D S S +N S+++ S+ + + Sbjct: 956 SSNSSDSSNS----SDSSDSN--------------SSDSSDSSNSSDSS--DSSDSSDSS 995 Query: 1125 VSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYA 1184 S D D ++ S S+ + ++ S + D + Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS----DSSDSSDSSDSSDSSDS 1051 Query: 1185 TDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT-STPSSNAKRQNQLHPSSAQSRSGQP 1243 +D +S S S S S SS + S SSE++ S+ SSN+ + SS S S Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111 Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303 ++ SS + ++ + D+ S S S S + D + ++ +DS+++ Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDS-SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170 Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSK 1363 ++ + + + D + + SS SS SS+S+ SS + S Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1230 Query: 1364 SGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSD 1422 S + S + S +S SS DS + S QS+ +G +G S SD Sbjct: 1231 SNESSDSSDSSDSSDSSNSSDSSDSSDSS-DSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288 Score = 60.5 bits (145), Expect = 2e-08 Identities = 88/511 (17%), Positives = 190/511 (37%), Gaps = 19/511 (3%) Query: 731 ANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQR 790 +N + D++ S S + + ++ D+ + S++ ++ D+ S S Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844 Query: 791 HKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDR 850 S D N SD+ ++ + + S +++ SS+S S DSS S Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904 Query: 851 SLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTT 910 S + + ++++ +S+ S+ ++ + + + ++S SS S+ Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964 Query: 911 ELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSS 970 + + N+ S ++++ ++ + S++S+ + S + S+DS NS SS Sbjct: 965 SSD--SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022 Query: 971 DGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLK 1030 + S S S D S + + ++ D+ D+ + Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082 Query: 1031 YSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQ 1090 S + +S S S + + D S+ S N S + ++S+D Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS----SDSSD------- 1131 Query: 1091 PHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEE 1150 + S ++ S + S+ + + S S D + +N S+ S + Sbjct: 1132 ----SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD--SSD 1185 Query: 1151 EQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEH 1210 + ++ S ++ D ++D S S S S S SS + Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245 Query: 1211 MSSSSENTSTPSSNAKRQNQLHPSSAQSRSG 1241 S+SS+++ + S+ + S +QS+SG Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 94.4 bits (233), Expect = 1e-18 Identities = 311/1595 (19%), Positives = 564/1595 (35%), Gaps = 198/1595 (12%) Query: 1331 RTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSV 1390 R++S +G S S R SS K+ S++ + +S ++++ + R S+ Sbjct: 703 RSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762 Query: 1391 SSLDSFESRSIA---SSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQ 1447 SS S ++ S S PC S +P S G + P ++S+TPP +++ Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQ--TPPRRSRS-GSSQPKAKSRTPPRRSRSSS 819 Query: 1448 TKREVPKNKAPTAEKRESG---PKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSS 1504 + K+K P+ + S PK + Q P A+ TP SC Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN-----EQSVTPQRRSCFE 874 Query: 1505 SLSALSLDEPFIQKDVELRIMPPVQENDNGN---ETESEQPKESNENQEKEAEKTIDSEK 1561 S D EL+ P + + +G+ +S P + ++ + + + Sbjct: 875 S-----------SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAII 923 Query: 1562 DLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQ 1621 S + S + SR + S+L P + S P K+ P Sbjct: 924 SPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPET 983 Query: 1622 NRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLS--------DLTIESPPNELAAGE 1673 Q G P TP S + S S D ++S P L+ Sbjct: 984 PPRQSHS------GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037 Query: 1674 GVRGGAQSGE-FEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAM 1732 GV+ GE + ++ +G+S + S + PE+ + +E + ++ + Sbjct: 1038 GVKSSTPPGESYFGVSSLQLKGQS--QTSPDHRSDTSSPEVRQSHSESPSLQSK--SQTS 1093 Query: 1733 PKG---KSHKPFRVKKIMDQVQQASASSSA-----PNKNQLDGKKKKPTSPVKPIPQNTE 1784 PKG +S P ++Q SA + + + +S + N+ Sbjct: 1094 PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153 Query: 1785 YRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPH 1844 + A+SK + +D+ + K + +DR S F Sbjct: 1154 LGQSRLETAESKEKM----ALPPQEDATASPPRQKDKFSPFPV---QDRPESSLVFKDTL 1206 Query: 1845 HYTPIE-----GTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTE 1899 P E +P +N +L + D++ +++ ++++E ++ SH Sbjct: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV---------VEKSEEPAGQILSHLS 1257 Query: 1900 LTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAA--------TDEKL 1951 + S + ++ + + Q QS + ++P ++ ++L Sbjct: 1258 SELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKEL 1317 Query: 1952 QNFAIE----NTPVCFSHNSSLSSLSDIDQENNNKE--NEPI---KETEPPDSQGEPSKP 2002 N + +P+ F ++ L + + + KE N P ET+P E S Sbjct: 1318 SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-T 1376 Query: 2003 QASGYAPKSFHVEDTPVC-FSRNSSLSSLSIDS--EDDLLQECISSAMPKKK-----KPS 2054 ++SG++ + S N S+SS +D+ + S++ P+ K PS Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436 Query: 2055 RLKGDNEKHSPRNMGGILG----EDLTLDLKDIQR-----------------------PD 2087 R R+ G + +KDI R P Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496 Query: 2088 SEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSP 2147 S SP+ N +E + S S + A L +++ S S L +K S Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556 Query: 2148 FHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKS--LITGKVRS 2205 + K T + + G +++K S + G K + +S Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616 Query: 2206 NSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASK----SP 2261 S+ S + K P +P SR + G SS++ S + PP A + SP Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676 Query: 2262 SEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQP-LSRP 2320 + T PR EL+ AR + + +S +P +R TP R + P +S P Sbjct: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE---TRSRTPPRHRRSPSVSSP 1733 Query: 2321 IQSPGRNSISPGRNGISPPNK-LSQLPRTSSPSTASTKSSGS-GKMSYTSPGRQMSQQNL 2378 + S R+ SP K S+ R+ SP + S S + T R+ + Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793 Query: 2379 TKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLV 2438 ++ T + RS S S+ + G+G + + + SS SS RS P Sbjct: 1794 SQSTSRRRQ-----RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848 Query: 2439 RQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSS 2498 R+ + + +P+P R + S PA+ RS+++TP++S S S S Sbjct: 1849 RKRSRSRTSPAPWKRSRSRAS-----------PATHRRSRSRTPLISRR---RSRSRTSP 1894 Query: 2499 VQAGGWRKLPPNLSPTIEYNDGR--PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSS 2556 V R+ S T + R P R RS S +P P+ R + R + Sbjct: 1895 VSR---RRSRSRTSVTRRRSRSRASPVSRR---RSRSRTP---PVTRRRSRSRTPTTRRR 1945 Query: 2557 SLPRVS--TWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614 S R T RR+ S + ++ S + + + S + + ++ T R+ Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRR 2005 Query: 2615 IKENEFSPTNSTSQTVSSGA-TNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGR 2673 + T S++ + A + S+T + + S++ R G+ Sbjct: 2006 SRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGK 2065 Query: 2674 SPTGNTPPVI--DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP 2731 +PP I S S ++ + + + + G+ + P+ +R++ F P Sbjct: 2066 RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL--NSSRMSCF---SRP 2120 Query: 2732 DQKGTEI----KPGQNNPVPVSETNESSIVE-----------RTPFSSSSSSKHSSPSGT 2776 T + PG P+ S T S + + R P +S + Sbjct: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSR 2180 Query: 2777 VAARVTPFNYNPS--PRKSSADSTSARPSQIPTPV 2809 +A +T + + P SA +AR SQ+P PV Sbjct: 2181 IALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215 Score = 85.1 bits (209), Expect = 9e-16 Identities = 209/977 (21%), Positives = 350/977 (35%), Gaps = 113/977 (11%) Query: 1878 KAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSS 1937 K +K K ESE+K H T + +K + + PK +ST S+ Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269 Query: 1938 KDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENE-PIKETEPPDSQ 1996 + T A T H ++L+ S E + P E +Q Sbjct: 270 SS-----SDTSRSRSRSAAAKT-----HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ 319 Query: 1997 GEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRL 2056 PS P+ + P S + + ++++ S S + SS P+ P+ L Sbjct: 320 -RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER---------SSTGPEPPAPTPL 369 Query: 2057 KGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVS-SL 2115 + SP+ + T ++ P SE SP + K+ ++ S S S Sbjct: 370 LAERHGGSPQPLA------TTPLSQEPVNPPSE--ASPTRDRSPPKSPEKLPQSSSSESS 421 Query: 2116 HQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKST 2175 + +SR ASS +S K + GS ++ K + + R + Sbjct: 422 PPSPQPTKVSRHASSSPESP---KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478 Query: 2176 LETKKIESESKGIKGGKKVYKSLITGKVRSNS---------EISGQMKQPLQANM----- 2221 + S + +G + G RS S + G+ + P + Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538 Query: 2222 -PSISRGRTMIHIPGVRNS----SSSTSPVSKKGPPLKTPASKSPSEGQT-ATTSPRGAK 2275 P SR R R++ S S SP ++ +TPA + S +T A R Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598 Query: 2276 PSVKSELS--PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333 P+ + S P R S+ S+ P+R SR +P R + S +S S +P R Sbjct: 599 PTRRRSRSRTPARRGRSR----SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654 Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 G S S+ P S + T + SG+ +P R+ ++ T + G S++ S + R Sbjct: 655 RGRSR----SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLR 2453 S S+ + ++++ SR S +S + S ++ + + + +P + Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770 Query: 2454 RKLEESASFESLSP-----SSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508 +L S SP S P +RS + P P + SS K P Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830 Query: 2509 -----PNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRS-----------GTWKREHS 2552 + SP + G P ++ I + S P RS HS Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890 Query: 2553 KHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTW 2612 SS PRV + S S SS K K+ S SG+ ++V+++ T Sbjct: 891 CSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947 Query: 2613 RKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672 R+ S++VS + ES+ L+ + + + S + D V+ E P + Sbjct: 948 RR------------SRSVS--PCSNVESR-LLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992 Query: 2673 RSP----TGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728 SP TPP K+ + SKD+ + G+ S+ S+ V Sbjct: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052 Query: 2729 DAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK-HSSPSGTVAARVTPFN-- 2785 + KG Q +P S+T+ + + S S SK +SP G + +P Sbjct: 1053 SSLQLKG----QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108 Query: 2786 YNPSPRKSSADSTSARP 2802 + SP + SA P Sbjct: 1109 ASRSPIRQDRGEFSASP 1125 Score = 83.2 bits (204), Expect = 3e-15 Identities = 377/1715 (21%), Positives = 612/1715 (35%), Gaps = 288/1715 (16%) Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNA-----------------KRQNQL 1231 +SQ++S S +SS + K+ S S + S+P S A K+++Q Sbjct: 736 TSQRRSRS---NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792 Query: 1232 HPSSAQSRSGQPQ-KAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC- 1289 P ++S S QP+ K+ T S + + TP SR S SS + + G Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP---SRQSHSSSSPHPKVKSGTP 849 Query: 1290 -NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQH-------PRTKSSRLQGSS 1341 Q + + AN + + + S+ DP + S+H PR KSS S Sbjct: 850 PRQGSITSPQANEQSVTP-QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908 Query: 1342 LSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401 S S+ V+ + S SG+ +P SP + TP R SVS + ESR + Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSP-SPSRVTSRTTP---RRSRSVSPCSNVESRLL 964 Query: 1402 ---ASSVQSEPCSGMV---------SGIISPSDLPDSPGQTMP-PSRSKTPPPPPQTAQT 1448 + S S P + + SG ISP P QT P PS S + P PQ Sbjct: 965 PRYSHSGSSSPDTKVKPETPPRQSHSGSISP--YPKVKAQTPPGPSLSGSKSPCPQEKSK 1022 Query: 1449 K---REVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLL-HFATESTPDGFSCSS 1504 + P + + A + S P + V +Q+ + T H + S+P+ S Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESY-FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081 Query: 1505 SLSALSLDEPFIQKDVELRIMPPVQE--------NDNGNETESE------QPKESNENQE 1550 +L K R PV E D G + S P++S + Sbjct: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSD 1141 Query: 1551 KEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPS 1610 + T+DS LL S + E E+ A+P + A P Q P PV +P Sbjct: 1142 SSSYPTVDS-NSLLGQSRLETAESKEK---MALPPQEDATASPPRQKDKFSPFPVQDRPE 1197 Query: 1611 QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELA 1670 V+K R P++ + P E N + TS D + + Sbjct: 1198 SSLVFK---DTLRTPPRER---SGAGSSP-----ETKEQNSALPTSSQDEELMEVVEKSE 1246 Query: 1671 AGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINS 1730 G S E ++ T E S+ E + S+T LD ++++ E + Sbjct: 1247 EPAGQILSHLSSELKEMSTSNFE--SSPEVEERPAVSLT---LDQSQSQASLEAVEVPSM 1301 Query: 1731 AMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVR 1790 A G H K++ S+S +N + S NT + + V+ Sbjct: 1302 ASSWGGPHFSPEHKEL---------SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352 Query: 1791 K--NADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTP 1848 + N N L + + D K+Q+ +++ ++ P+ ++ Sbjct: 1353 EDLNGPFLNQLETD----PSLDMKEQSTRSSGHSSSELSPDAVEKAG------------- 1395 Query: 1849 IEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSAN 1908 S N S+SS D SRE++ + E K+ + S Sbjct: 1396 -------MSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS-----------R 1437 Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDI---PDRG-AATDEKLQNFAIENTPVCFS 1964 ++++ + + G P S KDI P RG + D + A+ TP S Sbjct: 1438 RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS 1497 Query: 1965 HNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRN 2024 + S E NNK P +E S E S Q + V TP+ R+ Sbjct: 1498 RSPS-------SPELNNKCLTPQRER----SGSESSVDQKT--------VARTPL-GQRS 1537 Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDN--EKHSPRNMGGILGEDLTLDLKD 2082 S SS +D + SA P+++ S D+ + +P G +D K Sbjct: 1538 RSGSSQELDVK--------PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589 Query: 2083 IQRP-DSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSG 2141 P S G SP+ ++ A + + S S +A A L R++ S S S Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS-KGRGPS 1648 Query: 2142 ISLGSPFHLTPDQEEKPFTSNKGPRIL-KPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200 S +P+ K T+ +G R +P KS ++ S S +T Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS----------SPELT 1698 Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPAS-- 2258 K R + ++ A+ +R RT P R S S +SP P K+ +S Sbjct: 1699 RKARLS-------RRSRSASSSPETRSRTP---PRHRRSPSVSSP----EPAEKSRSSRR 1744 Query: 2259 -KSPSEGQTATTSPRGAKPSVKSELSPVARQTS--QIGGSSKAPSRSGSRDSTP-----S 2310 +S S +T TTS RG PS K +R S + +++ RSGS ST S Sbjct: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804 Query: 2311 RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPG 2370 R + R G +S SP R S + + R+ +P T+ +S S TSP Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS-----RSRTSPA 1859 Query: 2371 RQMSQQNLTKQTGLSKNASSIP-----RSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425 ++ ++ S P RS S + +++ + + + SR ++ S Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919 Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL- 2484 S PV R+S + +PT RR+ S +P P + RS+++TP + Sbjct: 1920 RRRSRSRTPPVTRRRS----RSRTPTTRRR------SRSRTP---PVTRRRSRSRTPPVT 1966 Query: 2485 -----SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESP--- 2536 S + P + S R+ SP RS S +P Sbjct: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI 2026 Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596 R +R+ R+ S+ S L RR S + +A + S +S S S Sbjct: 2027 RRRSRSRTPLLPRKRSRSRSPL----AIRRRSRSRTPRTARGKRS-LTRSPPAIRRRSAS 2081 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656 G+ + + T R + P S +S + L +P + + Sbjct: 2082 GSSSDRSRSATPPAT-RNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLE--- 2137 Query: 2657 VWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV 2716 P+ S R+P S+ + P I D + +N + + Sbjct: 2138 --------PLG---SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALAL- 2185 Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVP-VSETNESSIVERTPFSSSSSSKHSSPSG 2775 T I G P P +S ++ + + P S ++P+ Sbjct: 2186 -------------------TAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAA 2226 Query: 2776 TVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVN 2810 +A+R+ P+ ++ + SAR IPT VN Sbjct: 2227 NLASRI------PAASAAAMNLASARTPAIPTAVN 2255 Score = 66.2 bits (160), Expect = 4e-10 Identities = 106/436 (24%), Positives = 174/436 (39%), Gaps = 50/436 (11%) Query: 2209 ISGQMKQPLQANMPSISR---GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQ 2265 ++G P AN PS SR ++ G R S+ +T+PV+ G +T A+ +P+ Sbjct: 2311 LTGSGTPPTAANYPSSSRTPQAPASANLVGPR-SAHATAPVNIAGS--RTAAALAPASLT 2367 Query: 2266 TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTP----------SRPAQQ 2315 +A +P + ++ S P++ ++ G + P +R TP S A Sbjct: 2368 SARMAPALSGANLTSPRVPLSAY-ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426 Query: 2316 PLSRPIQSPGRNSISPGRNGI-SP-PNKLSQLPRT--------------SSPSTASTKSS 2359 P SR Q+P ++ + P ++ SP P+ S R SS + A+T SS Sbjct: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486 Query: 2360 G---SGKMSYTSPGRQMSQQNLTKQTGLSKNASSI----PRSESASKGLNQMNNGNGANK 2412 +G +S +PG S + ++ S++ P E S + ++ + ++ Sbjct: 2487 AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546 Query: 2413 KVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPA 2472 S SS+ SS S+S+ S PV + +K PSPT K A E P PA Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPV--QPEVALKRVPSPTPAPK---EAVREGRPPEPTPA 2601 Query: 2473 SPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSH 2532 R + + S S S S+ SS + + S + + PAK A Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661 Query: 2533 SESPSRLP----INRSGTWKREHSKHSSSLPRVSTWRRTGS-SSSILSASSESSEKAKSE 2587 SP + P +RS + + S SL RR S S S SSE+ Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721 Query: 2588 DEKHVNSISGTKQSKE 2603 ++ + K+ +E Sbjct: 2722 GQRGDSRSPSHKRRRE 2737 Score = 65.9 bits (159), Expect = 6e-10 Identities = 154/749 (20%), Positives = 262/749 (34%), Gaps = 102/749 (13%) Query: 2151 TPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEIS 2210 TP Q++K ++G R +S+ ++ + SK KK ++S K R + + Sbjct: 184 TPKQKKKKKKKDRGRR-----SESSSPRRERKKSSK-----KKKHRSESESKKRKHRSPT 233 Query: 2211 GQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTS 2270 + K+ ++ R R+ P R + STS S S+S + +T TT+ Sbjct: 234 PKSKR--KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA-AKTHTTA 290 Query: 2271 PRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLS------------ 2318 G PS S R+ S+ + S R S+P +QP S Sbjct: 291 LAGRSPSPAS-----GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345 Query: 2319 ---RPIQSPGRNSISPGRNGISP---------PNKLSQLPRTSSPSTASTKSSGSGKMSY 2366 RP SP R+S P +P P L+ P + P +++S + S Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405 Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSG 2426 ++ Q + ++ + S + + R S+S + G+++++ S S +S G Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465 Query: 2427 -SESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485 ++ D+S PS + R + + S S P S++++P Sbjct: 466 RAKRDKSH-----------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514 Query: 2486 PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI--ARSHSESP------- 2536 S S Q G + P + N R + RSHS SP Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574 Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596 SR P R + R ++ S R T RR+ S + S S A+ S Sbjct: 575 SRTPARRGRSRSRTPARRRSR-SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR----S 629 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656 ++ ++ A+ + R S S+T + + S+T + + S+T Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS--RSRTPARRSGRSRSRTP- 686 Query: 2657 VWVRIEDCPINNPRSGRSPTGNT---------PPVIDSVSEKANPNIKDSKDNQAKQNVG 2707 R PR GRS + + P S ++ S+ +Q + Sbjct: 687 --ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR-S 743 Query: 2708 NGSVPMRTVGLENRLNSFIQVDAPDQK----------GTEIKPGQNNPVPV----SETNE 2753 N S M+ + +R + + K G+ P Q + P S +++ Sbjct: 744 NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803 Query: 2754 SSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT 2813 RTP S SS P + + SP T R I +P N Sbjct: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQ 863 Query: 2814 KKRDSKTDSTESS-----GTQSPKRHSGS 2837 + ESS +++P RHS S Sbjct: 864 SVTPQRRSCFESSPDPELKSRTPSRHSCS 892 Score = 60.8 bits (146), Expect = 2e-08 Identities = 365/1994 (18%), Positives = 672/1994 (33%), Gaps = 337/1994 (16%) Query: 1023 TPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTEST 1082 TP S S + R P ++ + P + ++ RQS + S+ +P T Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP---PKQKSKTPSRQSHSSSSPHPKVKSGT 848 Query: 1083 DDKHLKFQPHFGQQECVSPYRS------------------RGANGSETNRVGSNHGINQN 1124 + ++ V+P R +GS RV S+ Q+ Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908 Query: 1125 VSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYA 1184 S+S +P + + H P+ + R S+ Sbjct: 909 PSRS-------SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR-----SRSVSPC 956 Query: 1185 TDIPSSQKQSFSFSKSSSGQSS-KTEHMSSSSENTS-TPSSNAKRQNQLHPSSAQSRSGQ 1242 +++ S +S S SSS + K E S + S +P K Q PS + S+S Sbjct: 957 SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPC 1016 Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL-SSLSSAEDEIGCNQTTQEADSANT 1301 PQ E + V+ P S C+ + SS E G + + S + Sbjct: 1017 PQ------------EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064 Query: 1302 LQIAEIKEKIGTRSAEDPVSEVPAVSQHPRT--KSSRLQGSSLSSESARHKAVEFSSGAK 1359 + + + SE P++ +T K R + SS +E A + G Sbjct: 1065 ---PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121 Query: 1360 SPS---KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSG 1416 S S KSG SP + Q + SS + +S S+ + E Sbjct: 1122 SASPMLKSGM----SPEQSRFQ---------SDSSSYPTVDSNSLLGQSRLETAESKEKM 1168 Query: 1417 IISPS-DLPDSPGQTMPPSRSKTPPPPPQTA--------QTKREVPKNKAPTAEKRESGP 1467 + P D SP P + K P P Q T R P+ ++ E+ Sbjct: 1169 ALPPQEDATASP----PRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKE 1224 Query: 1468 KQAAVNAAVQRVQVL--------PDADTLLHFATE---STPDGFSCSSSLS-----ALSL 1511 + +A+ + Q +++ P L H ++E + F S + +L+L Sbjct: 1225 QNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTL 1284 Query: 1512 DEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEA---------------EKT 1556 D+ Q +E +P + + G E + SN + + E Sbjct: 1285 DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMN 1344 Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQL---- 1612 ++ +D + + LE M +S+R + ++S+L P K Sbjct: 1345 TGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS---GHSSSELSPDAVEKAGMSSNQS 1401 Query: 1613 ---PVYKLLP-SQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNE 1668 PV +P + +R + S D +PR TP S + S SP Sbjct: 1402 ISSPVLDAVPRTPSRERSSSASSPEMKDGLPR------TPSRRSRSGS-------SPGLR 1448 Query: 1669 LAAGEGVRGGAQSGEFEKRDT--IPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAE 1726 +G R +D P+ GRS ++ + P ++ + Sbjct: 1449 DGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNK 1508 Query: 1727 CINSAMPKGKSHKPFRVKKIM-DQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEY 1785 C+ + S K + + Q S S S+ + + S P +++ Sbjct: 1509 CLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP-DSKA 1567 Query: 1786 RTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHH 1845 +TR S++ + E V S ++ S +++ +S DK P R + S + SP Sbjct: 1568 KTRTPLRQRSRSGSSPE-VDSKSRLSPRRSRSGSSPEVKDK-PRAAPRAQ-SGSDSSPEP 1624 Query: 1846 YTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQ 1905 P P R SR + + + E + S E + Sbjct: 1625 KAP---APRALPRR---------------SRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666 Query: 1906 SANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP----DRGAATDEKLQNFAIENTPV 1961 +A + + +P + + P + + P+ ++ R A++ + ++ TP Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS----RTPP 1722 Query: 1962 CFSHNSSLSSLSDIDQENNNKE----NEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDT 2017 + S+SS ++ +++ + P +T + KP+ + E T Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782 Query: 2018 PVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLT 2077 R+ S SS S ++++ SR + + + R GG Sbjct: 1783 RTTRRRDRSGSSQSTS---------------RRRQRSRSRS---RVTRRRRGG------- 1817 Query: 2078 LDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILS 2137 H SP A QE + + + SR+ S S Sbjct: 1818 ---------SGYHSRSP--------ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP 1860 Query: 2138 LKSGISLGSPFHLTPDQEEKPFTSNKGPR-----ILKPGEKSTLETKKIESESKGIKGGK 2192 K S SP + P S + R + + +S + S S+ + Sbjct: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920 Query: 2193 KVYKSLITGKVRSNSEI-SGQMKQPLQANMPSISRGRTMIHIPGV--RNSSSSTSPVSKK 2249 + +S R S + ++ ++ P ++R R+ P V R S S TSP++++ Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980 Query: 2250 GPPLKT-PASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS--RSGSRD 2306 +T P ++ S +T+ + R ++ S SPV R+ S+ S+ P R SR Sbjct: 1981 RSRSRTSPVTRRRSRSRTSPVTRRRSR----SRTSPVTRRRSR----SRTPPAIRRRSRS 2032 Query: 2307 STPSRPAQQPLSR-------------PIQSPGRNSIS---PGRNGISPPNKLSQLPRTSS 2350 TP P ++ SR P + G+ S++ P S S R+++ Sbjct: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092 Query: 2351 PSTASTKSSG--------SGKMS-YTSPGRQMSQQNLTKQTGLSK--NASSIPRSESASK 2399 P S S +MS ++ P + + + G+ + +S P S Sbjct: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQA 2152 Query: 2400 GLNQMNNG--------------NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445 G + M+ N A ++ L+ + + + L + + + Sbjct: 2153 GGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVP 2212 Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505 AP P + + +A+ S P++ A+ + A+TP + ++ T ++ A Sbjct: 2213 -APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271 Query: 2506 KLPPNLSPT-IEYNDGRPAKRHDIARSHSESPSRLP---INRSGTWKREHSKHSSSLPRV 2561 ++P+ + D R + + + +P+ L + SGT + SSS Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---- 2327 Query: 2562 STWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFS 2621 T + S++ + S+ ++ + +++ + A S Sbjct: 2328 RTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPA-----------LS 2376 Query: 2622 PTNSTSQTVSSGATNGAESKTLIYQMAPAVSKT-----EDVWVRIEDCPINNPRSGRSPT 2676 N TS V A +T + A S+T + E P + R G++P+ Sbjct: 2377 GANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPS 2436 Query: 2677 GNT---------PPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQ 2727 + PV + S+++ I + Q++ +G+V T + N + Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH-NGMLS 2495 Query: 2728 VDAPD------------------------QKGTEIKPGQNNPVPVSETNESSIVERTPFS 2763 V AP Q E + ++ S ++ SS + S Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555 Query: 2764 SSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDST 2823 S SSS S S PSP + A + R + P P K+R S + S+ Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSP--TPAPKEAVREGRPPEPTPAKRKRRSSSSSSS 2613 Query: 2824 ESSGTQSPKRHSGS 2837 SS + S S S Sbjct: 2614 SSSSSSSSSSSSSS 2627 Score = 58.5 bits (140), Expect = 9e-08 Identities = 144/715 (20%), Positives = 244/715 (34%), Gaps = 92/715 (12%) Query: 2169 KPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGR 2228 +P + +L + S S K KK K + S+S + K + S S + Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225 Query: 2229 TMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQ 2288 H S + +K TPA KS ++ + + + +S A + Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285 Query: 2289 --TSQIGGSSKAP----------------SRSGSRDSTPSRPAQQPLS------------ 2318 T+ + G S +P + S R S+P +QP S Sbjct: 286 THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345 Query: 2319 ---RPIQSPGRNSISPGRNGISP---------PNKLSQLPRTSSPSTASTKSSGSGKMSY 2366 RP SP R+S P +P P L+ P + P +++S + S Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405 Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSG 2426 ++ Q + ++ + S + + R S+S + G+++++ S S +S G Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465 Query: 2427 -SESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485 ++ D+S PS + R + + S S P S++++P Sbjct: 466 RAKRDKSH-----------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514 Query: 2486 PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI--ARSHSESP------- 2536 S S Q G + P + N R + RSHS SP Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574 Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596 SR P R + R ++ S R T RR+ S + S S A+ + + S Sbjct: 575 SRTPARRGRSRSRTPARRRSR-SRTPTRRRSRSRTPARRGRSRSRTPAR----RRSRTRS 629 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656 ++ ++ A+ + R S S+T + S+T + + S+T Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT--PARRGRSRSRTPARRSGRSRSRTP- 686 Query: 2657 VWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV 2716 R PR GRS + + S S + ++ K RT Sbjct: 687 --ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK-------SRTS 737 Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGT 2776 +R NS +P+ K + I ++ + + S + S SS S T Sbjct: 738 QRRSRSNS-----SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792 Query: 2777 VAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 R + P KS +R S P P K+ SKT S +S + SP Sbjct: 793 PPRRSRSGSSQPK-AKSRTPPRRSRSSSSPPP------KQKSKTPSRQSHSSSSP 840 Score = 58.5 bits (140), Expect = 9e-08 Identities = 329/1633 (20%), Positives = 558/1633 (34%), Gaps = 230/1633 (14%) Query: 1331 RTKSSRLQGSSLSSESAR--HKAVEFSSGAKSP------SKSGAQTPKSPPEHYVQETPL 1382 R KSS+ + SES + H++ S KS S+S PKS H Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268 Query: 1383 MFSRCTSVSSLDSFESRSIASSVQSEPCSGM----VSGIISPSDLPDS-PG--QTMPPSR 1435 S TS S SRS A+ + +G SG D P S PG T PS Sbjct: 269 ASSSDTSRS-----RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323 Query: 1436 SKTPPPPPQTAQTKREVPKNK------APTAEKRESGPKQAAVNAAVQRVQVLPDADTLL 1489 +T P + ++ K + +P+ E+ +GP+ P LL Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP-------------PAPTPLL 370 Query: 1490 HFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQ 1549 +P + + P Q+ V PP + + + + + P++ ++ Sbjct: 371 AERHGGSPQPLATT----------PLSQEPVN----PPSEASPTRDRSPPKSPEKLPQSS 416 Query: 1550 EKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVA-RK 1608 E+ S PTK SR A ++ P P + R+ Sbjct: 417 SSESSPP------------------------SPQPTKVSRHASSSPESPKPAPAPGSHRE 452 Query: 1609 PSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFS---TATSLSDLTIESP 1665 S P K S R + K S TP M R S T T SP Sbjct: 453 ISSSPTSKNR-SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP 511 Query: 1666 PNELAAGEGVRGGAQSGEFEKRDTIPTE---GRSTDEAQGGKTSSVTIPELDDNKAEEGD 1722 + G ++S + R P RS + + G++ S Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571 Query: 1723 ILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAP-----NKNQLDGKKKKPTSPVK 1777 + + +S P R + + + S P ++++ +++ T Sbjct: 572 RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR--S 629 Query: 1778 PIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGS 1837 P+ + + R+ R++ S++ A R S ++ + + S+ + R R Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR---RGRSRSRTPARRSGRSRSRTP 686 Query: 1838 FAFDSPHHYTPIEG----------------TPYCFSRNDSLSSLDFDDDDVDLSREKAEL 1881 TP G TP R+ S S ++ + Sbjct: 687 ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERK--------NKSRTSQ 738 Query: 1882 RKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP 1941 R+++ N E K + + S S+ +++A ++ + R L S P+ P Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS-----LSGSSPCPKQKSQTP 793 Query: 1942 DRGAATDEKLQNFAIENTPVCFSHNSSL-----SSLSDIDQENNNKENEPIKETEPPDSQ 1996 R + + Q A TP S +SS S + Q +++ P ++ P Q Sbjct: 794 PRRSRSGSS-QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852 Query: 1997 GEPSKPQASGYAP-----KSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKK 2051 G + PQA+ + F P SR S S S S + S+ P ++ Sbjct: 853 GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR-----VKSSTPPRQ 907 Query: 2052 KPSRLKGDNEKH----SPRNMGGILGEDLTLDLKDIQR--PDSEHGLSPDSENFDWKAIQ 2105 PSR K SPR G + R P +SP S N + + + Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHS-GSSSPSPSRVTSRTTPRRSRSVSPCS-NVESRLLP 965 Query: 2106 EGANSIVSSLHQAAAAACLSRQASSDSDSIL-----SLKSGISLGSPFHLTPDQEEKP-- 2158 ++S SS RQ+ S S S G SL P ++ K Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSL 1025 Query: 2159 FTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQ 2218 S G L G KS+ T ES G+ + +S + RS++ S +++Q Sbjct: 1026 VQSCPGSLSLCAGVKSS--TPPGESYF-GVSSLQLKGQSQTSPDHRSDTS-SPEVRQS-H 1080 Query: 2219 ANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSV 2278 + PS+ G SSS + ++ + P + S S + SP ++ Sbjct: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS 1140 Query: 2279 KSELSPVARQTSQIGGSSKAPSRSGSR-------DSTPSRPAQQPLSRP--IQSPGRNSI 2329 S P S +G S + S + D+T S P Q+ P +Q +S+ Sbjct: 1141 DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL 1200 Query: 2330 SPGRNGISPPNKLS---QLPRTSSPSTASTKSSGSGKM------SYTSPGRQMSQQNLTK 2380 +PP + S P T ++A SS ++ S G+ +S + Sbjct: 1201 VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL 1260 Query: 2381 QTGLSKNASSIPRSE---SASKGLNQMNNGNGANKKVELSRMSSTKS----SGSESDRSE 2433 + + N S P E + S L+Q + + + VE+ M+S+ S + S Sbjct: 1261 KEMSTSNFESSPEVEERPAVSLTLDQ-SQSQASLEAVEVPSMASSWGGPHFSPEHKELSN 1319 Query: 2434 RPVLVRQSTF---IKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPD 2490 P+ R+++F ++ S L ++ S E + P +Q +T PSL Sbjct: 1320 SPL--RENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN---GPFLNQLET---DPSLDM 1371 Query: 2491 MSLSTHSS-----------VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRL 2539 ST SS V+ G SP ++ P++ + S E L Sbjct: 1372 KEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431 Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTK 2599 P S S S P + T S S LS SS + + + + Sbjct: 1432 PRTPS------RRSRSGSSPGLRDGSGTPSRHS-LSGSSPGMKDIPRTPSRGRSECDSSP 1484 Query: 2600 QSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKT---ED 2656 + K + + R E + T Q SG+ + + KT+ S++ ++ Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544 Query: 2657 VWVRIEDCPINNPRSGRSPTGNTP---PVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713 + V+ P S SP P+ ++P + DSK + + +GS P Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV-DSKSRLSPRRSRSGSSPE 1603 Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSP 2773 ++++ + + + E K +P + SS R P SSS SSP Sbjct: 1604 ----VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP 1659 Query: 2774 SGTVAARVT--PFNYNPSPRKSSADSTSARPSQIPTPVNNNTK--KRDSKTDSTESSGTQ 2829 +R +P P+ S R S+ + + +R S+ + ++ Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719 Query: 2830 SPKRHSGSYLVTS 2842 +P RH S V+S Sbjct: 1720 TPPRHRRSPSVSS 1732 Score = 54.7 bits (130), Expect = 1e-06 Identities = 73/280 (26%), Positives = 111/280 (39%), Gaps = 43/280 (15%) Query: 1214 SSENTSTPSSN---AKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPIC 1270 +SE +PSS A Q+ L P+ Q RS P S + + + TP+ Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP---------SAFSDQSRCLIAQTTPVA 2470 Query: 1271 FSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAV--SQ 1328 S+ S ++++ G + + A + +++ E + A+ P S + A+ ++ Sbjct: 2471 GSQSLSSGAVATTTSSAG-DHNGMLSVPAPGVPHSDVGEPPASTGAQQP-SALAALQPAK 2528 Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSP-------------PEH 1375 R+ SS SS SS S+ + SSG+ S G+ P P P+ Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588 Query: 1376 YVQE------TPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQ 1429 V+E TP R +S SS S S S +SS S S S S S S Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--- 2645 Query: 1430 TMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQ 1469 S S +P P A K PK K P E+R P++ Sbjct: 2646 ----SSSPSPAKPGPQALPKPASPK-KPPPGERRSRSPRK 2680 Score = 53.5 bits (127), Expect = 3e-06 Identities = 113/557 (20%), Positives = 187/557 (33%), Gaps = 81/557 (14%) Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 S + GSS P R P+ +P S +S S +P + + +S Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203 Query: 2350 SPSTASTKS---------SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400 SP KS S S K + SP + +++ K+ S++ + P+S A + Sbjct: 204 SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263 Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK-EAPSPTLRRKLEES 2459 + S SS + RS +T + +PSP R+ E Sbjct: 264 ----------------TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGD 307 Query: 2460 ASFESLSPSS--RPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY 2517 A F +S RP+SP +T PS P ++ P S T Sbjct: 308 APFSEPGTTSTQRPSSP-----ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSST--- 359 Query: 2518 NDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSAS 2577 PA +A H SP P+ + + + S + P + R S L S Sbjct: 360 GPEPPAPTPLLAERHGGSPQ--PLATTPLSQEPVNPPSEASP--TRDRSPPKSPEKLPQS 415 Query: 2578 SESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG 2637 S S S V+ + + A G+ R+I + S S + + + Sbjct: 416 SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSH 475 Query: 2638 AESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDS 2697 S+ + +PA +K R + + P S +P + S Sbjct: 476 TPSRRMGRSRSPATAK-------------------RGRSRSRTPTKRGHSRSRSPQWRRS 516 Query: 2698 KDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIV 2757 + + Q G P R + + +PG + S Sbjct: 517 R---SAQRWGRSRSPQRR----------------GRSRSPQRPGWSRSRNTQRRGRSRSA 557 Query: 2758 ER-TPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKR 2816 R S S +++ S S T A R + P+ R+S + + + R S+ TP + Sbjct: 558 RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR- 616 Query: 2817 DSKTDSTESSGTQSPKR 2833 S+T + S T+SP R Sbjct: 617 -SRTPARRRSRTRSPVR 632 Score = 48.5 bits (114), Expect = 9e-05 Identities = 78/379 (20%), Positives = 136/379 (35%), Gaps = 42/379 (11%) Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQ 2084 S+ +S + LL S P SR+ + MG + L +D Sbjct: 2388 SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQP 2447 Query: 2085 RPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKS-GI- 2142 R S S + + + S ++ A + ++ D + +LS+ + G+ Sbjct: 2448 RSPVPSAFSDQS-----RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502 Query: 2143 --SLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200 +G P T Q+ + L+P ++ + S S S + Sbjct: 2503 HSDVGEPPASTGAQQPSALAA------LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556 Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260 G S+SE S P+Q P ++ R P + + V + PP TPA + Sbjct: 2557 GSSSSDSEGSSL---PVQ---PEVALKRVPSPTPAPKEA------VREGRPPEPTPAKRK 2604 Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320 ++++S + S S S + +S SS + S S S +P++P Q L +P Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662 Query: 2321 IQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMS---QQN 2377 SP + P + S+ PR S ++S + P Q S QQ+ Sbjct: 2663 -ASPKKP---------PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712 Query: 2378 LTKQTGLSKNASSIPRSES 2396 + + G + RS S Sbjct: 2713 SSSERGSRRGQRGDSRSPS 2731 Score = 43.9 bits (102), Expect = 0.002 Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 20/197 (10%) Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQN-QLHPSSAQSRSGQPQKA 1246 P+ +++S S S SSS SS + SSSS ++ + SS+++ + + P A R P A Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585 Query: 1247 ATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAE 1306 + + E TP R SS SS SS+ + ++ + S+++ + Sbjct: 2586 P-------KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638 Query: 1307 IKEKIGTRSAEDPVSEVPAVSQHP-----------RTKSSRLQGSSL-SSESARHKAVEF 1354 + S+ P P P R++S R SL S S + VE Sbjct: 2639 SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698 Query: 1355 SSGAKSPSKSGAQTPKS 1371 + PS Q+ S Sbjct: 2699 RRPSPQPSPRDQQSSSS 2715 Score = 43.5 bits (101), Expect = 0.003 Identities = 57/244 (23%), Positives = 88/244 (36%), Gaps = 24/244 (9%) Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378 PV+ ++S ++ G S V S + P+ +GAQ P + Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA----LAA 2523 Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438 P R +S SS S S S +SS S SG S S LP P + R + Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL--KRVPS 2581 Query: 1439 PPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPD 1498 P P P+ A + P P KR S ++ +++ + + ++ S+ Sbjct: 2582 PTPAPKEA-VREGRPPEPTPAKRKRRSSSSSSSSSSS-------SSSSSSSSSSSSSSSS 2633 Query: 1499 GFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTID 1558 S SSS S+ S P K + P S + E + + K ID Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPA----------SPKKPPPGERRSRSPRKPID 2683 Query: 1559 SEKD 1562 S +D Sbjct: 2684 SLRD 2687 Score = 43.1 bits (100), Expect = 0.004 Identities = 72/340 (21%), Positives = 119/340 (35%), Gaps = 54/340 (15%) Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581 P K + + R S S S P + K++ + S S SS Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSES-------------------SSPRR 207 Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTV-------SSGA 2634 E+ KS +K S S +K+ K + K RK K+ + + ST+ S+ A Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSK-RKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266 Query: 2635 TNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTP---PVIDSVSEKAN 2691 + + S T + A +KT + +P SGR G+ P P S ++ Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSS 323 Query: 2692 PNIK--------DSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP-----DQKGTEI 2738 P + KD K+ P R ++ + AP ++ G Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPS-----PERSSTGPEPPAPTPLLAERHGGSP 378 Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADST 2798 +P P+ N S T S S P + + P +P P K S ++ Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP---SPQPTKVSRHAS 435 Query: 2799 SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838 S+ S P P + ++ S S S ++ + S S+ Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSH 475 Score = 40.4 bits (93), Expect = 0.025 Identities = 61/261 (23%), Positives = 92/261 (35%), Gaps = 24/261 (9%) Query: 2082 DIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSG 2141 D+ P + G S A+Q SS +++++ S +SS S S S Sbjct: 2505 DVGEPPASTGAQQPSA---LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561 Query: 2142 ISLGSPFHLTPDQEEKPFTS-----NKGPRILKPGEKSTLETKKIESESKGIKGGKKVYK 2196 S GS + P+ K S + R +P E + + K+ S S Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621 Query: 2197 SLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTP 2256 S + S+S S ++ S S P + P S K PP Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPS--------PAKPGPQALPKPASPKKPPPGER 2673 Query: 2257 ASKSPSEGQTATTSPRGA--KPSVKSELSPVARQTSQIGGSSKAPSRSG----SRDSTPS 2310 S+SP + + R P + SP Q SS+ SR G SR + Sbjct: 2674 RSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733 Query: 2311 RPAQQPLSRPIQSPGRNSISP 2331 R + P RP++ R+S SP Sbjct: 2734 RRRETPSPRPMRH--RSSRSP 2752 Score = 32.7 bits (73), Expect = 5.2 Identities = 22/71 (30%), Positives = 32/71 (45%) Query: 1175 QPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 +P K + SS S S S SSS SS + SSSS ++S+ SS++ Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656 Query: 1235 SAQSRSGQPQK 1245 A + P+K Sbjct: 2657 QALPKPASPKK 2667 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 90.1 bits (222), Expect = 3e-17 Identities = 337/1722 (19%), Positives = 610/1722 (35%), Gaps = 214/1722 (12%) Query: 1185 TDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTP--SSNAKRQNQLHPSSAQSRSGQ 1242 T I S + + S + S T S++ TST SS+ + P+S + Sbjct: 629 TTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGST 688 Query: 1243 PQKAA---TCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADS 1298 P + T V+S T+ T V+ TP+ S +S SS ++A+ T+ ++ Sbjct: 689 PLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS-SSPTTADG--ASMPTSTPSEG 745 Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358 + L + + + T S +S P + T S+ S ++E S G+ Sbjct: 746 STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGS 805 Query: 1359 KSPSKSGAQ-TPKSPPEHYVQETPLMFSRC-----TSVSSLDS-FESRSIASSVQSEPCS 1411 + TP + PE T + S T VSS + E S+ +S SE + Sbjct: 806 PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865 Query: 1412 GMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA 1471 + S +S + + S T+ + T P + + + +PT + S P Sbjct: 866 PLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR------SSPTTSEGTSMPTSTP 919 Query: 1472 VNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPF-IQKDVELRIMPPVQE 1530 + +PD+ +TP S + +LSA +D + E P E Sbjct: 920 GEGSTPLTS-MPDS---------TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAE 969 Query: 1531 NDNGNETESEQPKESNE---NQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKS 1587 G + P E + +SE L + D L ++ P + Sbjct: 970 ---GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026 Query: 1588 SRKAKKPAQTASKLPPPVARKP--------------SQLPVYKLLPSQNRLQPQKHVSFT 1633 + P T S+ P+ R P S P P Q + Sbjct: 1027 AEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA 1086 Query: 1634 PGDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKR 1687 G MP EG+ P++ S T+ + P + + Sbjct: 1087 DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPV-------------- 1132 Query: 1688 DTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIM 1747 T TE S+ G + + P + + S+ S P K Sbjct: 1133 -TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKT-- 1189 Query: 1748 DQVQQASASSSAPNKNQLD-------GKKKKPTS--PVKPIP-QNTEYRTRVRKNADSKN 1797 QV ++ +SS P ++ G++ P + PV+ P ++E T D+ Sbjct: 1190 -QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTST 1248 Query: 1798 NLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFS 1857 + S + + + LP + GS S P+ T Sbjct: 1249 PVTTSAETSSSPTTAE----------GTSLPTSTTS-EGSTLLTS----IPVSTTLVTSP 1293 Query: 1858 RNDSLSSLDFD-------DDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQ--SAN 1908 +L + D ++V S AE + SE + T T + N +++ Sbjct: 1294 EASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR-TPLTSIPVNTTLVASS 1352 Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDE---KLQNFAIENTPVCFSH 1965 ++ P++ P + + P +S+ + E L + + TPV S Sbjct: 1353 AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSE 1412 Query: 1966 NSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRN 2024 S+LS+ E + P+ + G P KS V +TPV S Sbjct: 1413 ASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEA 1472 Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQ 2084 S+LS+ +DS ++ S+ P + + + + I T+ Sbjct: 1473 STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV------ 1526 Query: 2085 RPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISL 2144 A+S ++SL A S + S + G S+ Sbjct: 1527 -----------------------ASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSM 1563 Query: 2145 GSPFHLTPDQEEKPFTSNK-GPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKV 2203 + T + P TS ++ E +TL T I+S+++ + S T + Sbjct: 1564 QTS---TYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEA--SSSTTAEG 1618 Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPS 2262 S + + PL ++P + T + P S+ ST+PV P + T S SP+ Sbjct: 1619 SSMTISTPSEGSPLLTSIPVST---TPVASPEA--STLSTTPVDSNSPVITSTEVSSSPT 1673 Query: 2263 EGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP-SRSGSRDSTPSRPAQQPLSRPI 2321 + T+ P ++ L+ + +T+ + S+ + S + +STP + + S P Sbjct: 1674 PAE-GTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPT 1732 Query: 2322 QSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381 S G + P L+ +P +++P +S S+ S TS S + + Sbjct: 1733 TSEGTSM--PNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSP 1790 Query: 2382 TGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQS 2441 T + +SIP S + S+G+ + + ++ V S S+ ++ +S+ PV+ S Sbjct: 1791 T--TAEGTSIPTS-TLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS---PVVT--S 1842 Query: 2442 TFIKEAPSPTLRRKLEESASFE-SLSPSSRPASPTR---SQAQTPVLSPSLPDMSLSTHS 2497 T + +P+P + S E S + +S P S T S+ T +P++ ++T++ Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYA 1902 Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSS 2557 V + ++ PT +GRP + +P++ + E + S++ Sbjct: 1903 QVSSSPTTADGSSM-PTSTPREGRPPL------------TSIPVSTTTVASSEINTLSTT 1949 Query: 2558 LPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKE 2617 L T T S +S +++ + + ++ S VS++ + Sbjct: 1950 LADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAS------ 2003 Query: 2618 NEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR--SGRSP 2675 S T + T ++ +T G+ S T + S + + P++ S Sbjct: 2004 -TLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGN 2062 Query: 2676 TGNTPPVIDSVSEKANPNIKDSKDNQAKQNV-----GNGSVPMRTVGLENRLNSFIQVDA 2730 T +T PV DS ++ N S ++ GS + ++ L S V + Sbjct: 2063 TLSTTPV-DSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL-----STTPVAS 2116 Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSP 2790 P+ P +N ++ T SS +P + +S +S +T + + Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSS----SPIPTEGTSMQTSTYSDRRTPLTSMPVSTTV 2172 Query: 2791 RKSSADST-SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 SSA ST S P TPV N+T+ R S T S GT P Sbjct: 2173 VASSAISTLSTTPVDTSTPVTNSTEARSS---PTTSEGTSMP 2211 Score = 85.5 bits (210), Expect = 7e-16 Identities = 365/1792 (20%), Positives = 609/1792 (33%), Gaps = 282/1792 (15%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSS-KTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 I+ S+ T SS + + + S+++S +S T SS+E+TS+P++ + S Sbjct: 94 IESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPS 153 Query: 1236 AQSRSGQPQKAATCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQ 1294 +S S +T + S T TY V+ TP+ S +S SS ++ E T Sbjct: 154 EESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQAS-SSPTTPESTTIPKSTNS 212 Query: 1295 EADS------ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESAR 1348 E + A+T+++A E I + +S +S + + +G SLS+ + Sbjct: 213 EGSTPLTSMPASTMKVAS-SEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPS 271 Query: 1349 HKAVEFSSGAKSPS---KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSV 1405 + + S S A T + P P++ S S SS + E SI +S Sbjct: 272 GGSTPLTRMPLSVMLVVSSEASTLSTTPA--ATNIPVITSTEAS-SSPTTAEGTSIPTST 328 Query: 1406 QSEPCSGMVSGIISPSDLPDSPGQTMPPSRSK-----TPPPPPQTAQTKREVPKNKAPTA 1460 +E + L +P TMP + S+ P T T P + TA Sbjct: 329 YTE----------GSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTA 378 Query: 1461 EKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE----PFI 1516 E + + ++ + +P + L+ + ST S + E P Sbjct: 379 E--ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTT 436 Query: 1517 QKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEK----TIDSEKDLLDDSDDDDI 1572 +D + P G+ + P + EA +DS+ + ++ Sbjct: 437 AEDTSIATSTP----SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSS 492 Query: 1573 EILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSF 1632 E +++MPT + + P + S PVA + +S Sbjct: 493 PPTAE--VNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST-----------------LST 533 Query: 1633 TPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPT 1692 TP D TP+ S+ S S T E + + R + + Sbjct: 534 TPVD--------TSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585 Query: 1693 EGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQ 1752 E +T + VT ++A AE ++MP ++ Sbjct: 586 EASTTSTTPADSNTFVT----TSSEASSSSTTAE--GTSMPTS------------TYSER 627 Query: 1753 ASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSK 1812 + +S L + T P+ NT T + S + S Sbjct: 628 GTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSST---------TAEGTSM 678 Query: 1813 KQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIE-GTPYCFSRNDSLSSLDFDDDD 1871 + +P N V S A S TP++ TP S S S D Sbjct: 679 PTSTYTEGSTPLTSMPVNTTLVASSEA--STLSTTPVDTSTPVTTSTEASSSPTTADGAS 736 Query: 1872 VDL---SREKAELRKAKENK----ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPK 1924 + S L +K SEA S T L ++ T+A G Sbjct: 737 MPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796 Query: 1925 PILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKEN 1984 PI P G+ L + + TPV S+LS+ Sbjct: 797 PI------------STPSEGSPL---LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTST 841 Query: 1985 EPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECI 2043 E P + P+ + G P S V T V S S+LS+ +D+ + Sbjct: 842 EVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901 Query: 2044 SSAMPKKKK----PSRLKGDNE---KHSPRNMGGILGED---LTLDLKDIQRP---DSEH 2090 + + P + P+ G+ P + ++ + L+ D P +E Sbjct: 902 ARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEA 961 Query: 2091 GLSP---DSENFDWKAIQEGANSIVSS--LHQAAAAACLSRQASSDSDSILSLKSGISLG 2145 SP + + EG + S+ H A + S +++ DS L + Sbjct: 962 TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS 1021 Query: 2146 SPFHL---------TPDQEEKPFTSNK-GPRILKPGEKSTLETKKIE-----------SE 2184 SP TP + P T ++ E STL T + S Sbjct: 1022 SPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASS 1081 Query: 2185 SKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTS 2244 S G + S + + + + + + ++S IP ++ +S+S Sbjct: 1082 SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS 1141 Query: 2245 PVSKKGPPLKTPASKSPSEGQTATTS-PRGAKPSVKSE-----LSPVARQTSQIGGSSKA 2298 P + +G + T PSEG T S P V SE +PV +T Q+ S++A Sbjct: 1142 PTTAEGTSIPT---SPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKT-QVATSTEA 1197 Query: 2299 PSRSGSRDSTPSRPAQQPLSR------------PIQSPGRNSISPGRNGISPPNKLSQLP 2346 S + + T S P P R P+ S +++S S P S Sbjct: 1198 SSPPPTAEVT-SMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTS-AE 1255 Query: 2347 RTSSPSTA-------STKSSGSGKMS--------YTSPGRQMSQQNLTKQTGLSKNASSI 2391 +SSP+TA ST S GS ++ TSP G ++ + Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEV 1315 Query: 2392 PRSESASKGLNQMNN--GNGANKKVELSRMSSTKSSGSESDRSERPV----LVRQSTFIK 2445 S + ++G + + G + ++ +S + S S PV V ST Sbjct: 1316 SSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEAC 1375 Query: 2446 EAPSPTLRRKLEESASFESLSP-SSRPASPT---RSQAQTPVLSPSLPDMSLSTHSSVQA 2501 +P+ + + S E +P +S P S T S+A T LS + D S +S +A Sbjct: 1376 SSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST--LSATPVDTSTPGTTSAEA 1433 Query: 2502 GGWRKLPPNLS-PTIEYNDGR------PAKRHDIARSHSESPSRLPINRSGTWKREHSKH 2554 +S PT ++G+ P +A S + + S P++ + + Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVS 1493 Query: 2555 SSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT-----------KQSKE 2603 SS P T + S +A + + +NS+S T Q+ Sbjct: 1494 SSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS 1553 Query: 2604 NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIED 2663 + +A GT + T TS VS+ +E+ TL P SKT+ + Sbjct: 1554 SPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL--STTPIDSKTQ--VTASTE 1609 Query: 2664 CPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLN 2723 + G S T +TP + +P + S+P+ T Sbjct: 1610 ASSSTTAEGSSMTISTP-------SEGSPLLT--------------SIPVSTT------- 1641 Query: 2724 SFIQVDAPDQKGTEIKPGQNNPVPVSETNESSI---VERTPFSSSSSSKHSSPSGTVAAR 2780 V +P+ P +N ++ T SS E T +S+ ++ +P ++ R Sbjct: 1642 ---PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVR 1698 Query: 2781 VTPFNYNPSPRKSSADST-SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 TP SSA ST S P TPV +T+ R S T S GT P Sbjct: 1699 TTPV-------ASSAISTLSTTPVDNSTPVTTSTEARSS---PTTSEGTSMP 1740 Score = 81.6 bits (200), Expect = 1e-14 Identities = 339/1720 (19%), Positives = 594/1720 (34%), Gaps = 207/1720 (12%) Query: 1200 SSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETI 1259 S+ G SS T +S TSTPS + S+ S + +T V S Q T Sbjct: 2019 STEGSSSPTT-AGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTN 2077 Query: 1260 QTYC-----VEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTR 1314 T E + + S S S L ++ I + T + A+TL + Sbjct: 2078 STEASSSATAEGSSMTISAPSEGSPLLTS---IPLSTTPVASPEASTLSTTPV------- 2127 Query: 1315 SAEDPVSEVPAVSQHP-RTKSSRLQGSSLSSESARHKAVEFSSG--AKSPSKSGAQTPKS 1371 + PV VS P T+ + +Q S+ S ++ S+ A S + + TP Sbjct: 2128 DSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVD 2187 Query: 1372 PPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTM 1431 T S TS E S+ +S SE + S +S + S T+ Sbjct: 2188 TSTPVTNSTEARSSPTTS-------EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTL 2240 Query: 1432 PPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHF 1491 S TP T E +PT + S P + ++ + +P + TL+ Sbjct: 2241 ----SATPVDTSTPVTTSTEA--TSSPTTAEGTSIPT-STLSEGTTPLTSIPVSHTLVAN 2293 Query: 1492 ATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEK 1551 + ST S + + + PF E PP E + + S + Sbjct: 2294 SEVST-------LSTTPVDSNTPFTTS-TEASSPPPTAEGTSMPTSTSSEGNTPLTRMPV 2345 Query: 1552 EAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKP-S 1610 E L + D + + ++ P T S+ P+ P S Sbjct: 2346 STTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVS 2405 Query: 1611 QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIE------S 1664 +PV S + S TP D TP+ ST S S T E S Sbjct: 2406 TMPVVSSEASTH--------STTPVDT--------STPVTTSTEASSSPTTAEGTSIPTS 2449 Query: 1665 PPNE----LAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPE---LDDNK 1717 PP+E LA+ S E T P + + +SS T E + + Sbjct: 2450 PPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST 2509 Query: 1718 AEEGDILAECINS-----AMPKGKSHKPFRVKK---IMDQVQQASASSSAPNKNQLDGKK 1769 A EG L I A P+ + V ++ + +S+++SA + Sbjct: 2510 ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569 Query: 1770 KKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPN 1829 + ++P++ +P +T+ + S ++ + + ++ P+ Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS 2629 Query: 1830 NEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFD-------DDDVDLSREKAELR 1882 S + P S +LS+ D S AE Sbjct: 2630 EVSTSLTSIL---------VSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680 Query: 1883 KAKENKESEAKVTSHTELTSNQQSAN-KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP 1941 + E L S AN + ++ P++ P + S+ P +++ Sbjct: 2681 SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS 2740 Query: 1942 DRGAATDE---KLQNFAIENTPVCFSHNSSLSSLS-DIDQENNNKENEPIKETEPPDSQG 1997 R + + L + + PV S S++S+ + D T + Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSM 2800 Query: 1998 EPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLK 2057 S P + S V TPV S +LS+ +D+ ++++ P+ + Sbjct: 2801 PTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTP-----VTTSTKASSSPTTAE 2855 Query: 2058 GDNEKHSPRNMGGILGEDLTLDLKDIQRP----------DSEHGLSPDSENFDWKAIQEG 2107 G S + G L + + + D+ ++ +E EG Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEG 2915 Query: 2108 ANSIVSSLHQAAA---AACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSN-K 2163 + +S+ + + + +S + S++ + + +P + + P T+ Sbjct: 2916 TSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGT 2975 Query: 2164 GPRILKPGEKSTLETKK-------IESESKGIKGGKKVYKSLITGKVRSNS-----EISG 2211 I PGE+ T T SE+ + + +T ++S E +G Sbjct: 2976 SMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTG 3035 Query: 2212 -QMKQPLQANMP--SISRGRTMIHIPGVRNSSSSTSPVSKKGPPL---KTPASKSPSEGQ 2265 + P + + P SI T + IP S+ ST+PV P + + +S +P+EG Sbjct: 3036 IPISTPSEGSTPLTSIPVSTTPVAIPEA--STLSTTPVDSNSPVVTSTEVSSSPTPAEGT 3093 Query: 2266 TA--TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQS 2323 + +T G+ P +S +S I S P + STP + + S P S Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT----STPVTTSTEAHSSPTTS 3149 Query: 2324 PGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTG 2383 G + + + S P L+ +P ++ +S S+ S TS S + + T Sbjct: 3150 EGTSMPTSTPSEGSTP--LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTA 3207 Query: 2384 LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTF 2443 +SIP S + S+G+ + + +N V S S ++ +S+ + ST Sbjct: 3208 ---EGTSIPTS-TPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP-----LTTSTE 3258 Query: 2444 IKEAPSPTLRRKLEESASFESLSP-SSRPASPTR-SQAQTPVLSPSLPDMSLSTHSSVQA 2501 +P + S E +P +S P S T + ++T LS + D S + QA Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318 Query: 2502 GGWRKLPPNLS-PTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPR 2560 + S PT Y++G S + + + + E S S++ Sbjct: 3319 SSSPPIADGTSMPTSTYSEG------------STPLTNMSFSTTPVVSSEASTLSTTPVD 3366 Query: 2561 VSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEF 2620 ST T + +S+ ++E + S + ++ S VS++ N Sbjct: 3367 TSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSE-------VNTL 3419 Query: 2621 SPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNP--RSGRSPTGN 2678 S T S T+ + +T + S T+ + S T + + P++ S + T + Sbjct: 3420 STTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLS 3479 Query: 2679 TPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEI 2738 T PV + + P S N + S+P T G + T + Sbjct: 3480 TTPV-----DTSTPVTTSSPTNSSPTTAEVTSMPTSTAG---------------EGSTPL 3519 Query: 2739 K--PGQNNPVPVSETNESSI--VERTPFSSSSSSKHSSPSG---TVAARVTPFNYNPSPR 2791 P PV SE + S V+ F +SSS SSP+ T TP + S Sbjct: 3520 TNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT 3579 Query: 2792 KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 ST S+ TP + + T ST+S+ T +P Sbjct: 3580 TMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTP 3619 Score = 79.7 bits (195), Expect = 4e-14 Identities = 335/1756 (19%), Positives = 608/1756 (34%), Gaps = 218/1756 (12%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSN-----AKRQNQ 1230 P+ S + ++ +++ S S +S G + T S++ TS +S + Sbjct: 1249 PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308 Query: 1231 LHPSSAQSRSGQPQKAATCKVSSINQ-ETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289 + S+ S S P + + S+ ++ T T +T + S S+ S + ++ Sbjct: 1309 VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPV 1368 Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAED----PVSEVPAVSQHPRTKSSRLQGSSL--- 1342 +T+ S T + + + PVS P VS T S+ +S Sbjct: 1369 TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGT 1428 Query: 1343 -SSESARHKAVEFSSGAKSPSKSGAQTP-KSPPEHYVQETPLMFSRCTSVSS--LDSFES 1398 S+E+ + + S +TP KS P V TP+ S +++S+ +DS Sbjct: 1429 TSAEATSSPTTAEGISIPTSTPSEGKTPLKSIP---VSNTPVANSEASTLSTTPVDSNSP 1485 Query: 1399 RSIASSVQSEP--CSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNK 1456 +++V S P G I +PS+ + ++P S + + T V Sbjct: 1486 VVTSTAVSSSPTPAEGTSIAISTPSE-GSTALTSIPVSTTTVASSEINSLSTTPAVTSTP 1544 Query: 1457 APTAEKRESGPKQA--------AVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSA 1508 T + S P A + + LP + L+ + +T S Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604 Query: 1509 LSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT----IDSEKDLL 1564 + E E M + G+ + P + EA +DS ++ Sbjct: 1605 TASTEASSSTTAEGSSMT-ISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVI 1663 Query: 1565 DDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKP----SQLPVYKLLPS 1620 ++ E ++MPT + + + P + + PVA S PV P Sbjct: 1664 TSTEVSSSPTPAEG--TSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV 1721 Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEG 1674 + + + + G MP EGT P++ + S T+ + P + + Sbjct: 1722 TTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT 1781 Query: 1675 VRGGAQSGEFEKRDT-IPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMP 1733 A S T IPT S E TS+ L N +E + ++S P Sbjct: 1782 TSTEATSSPTTAEGTSIPTSTLS--EGMTPLTSTPVSHTLVAN-SEASTLSTTPVDSNSP 1838 Query: 1734 KGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNA 1793 V ++A SS+P +G ++P + T A Sbjct: 1839 ----------------VVTSTAVSSSPTP--AEGTSIATSTPSEGSTALTSIPVSTTTVA 1880 Query: 1794 DSKNNL--NAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEG 1851 S+ N V S + Q + + +P + R P P+ Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP-----PLTSIPVST 1935 Query: 1852 TPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKES---EAKVTSHTELTSNQQS-- 1906 T S ++LS+ D + +A + S A T LTS S Sbjct: 1936 TTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTT 1995 Query: 1907 ---ANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEK---LQNFAIENTP 1960 +++ ++ P++ P + S+ P ++ + + E+ L + T Sbjct: 1996 LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTL 2055 Query: 1961 VCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVC 2020 V S ++LS+ + E S S P S + TPV Sbjct: 2056 VVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVA 2115 Query: 2021 FSRNSSLSSLSIDSEDDLLQ--ECISSAMPKKKKPSRLKGDNEKHSPRN---MGGILGED 2075 S+LS+ +DS ++ E SS +P + + +++ +P + + Sbjct: 2116 SPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVAS 2175 Query: 2076 LTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSI 2135 + D+ ++ +E EG + S+ + + S + Sbjct: 2176 SAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT--------SMPV 2227 Query: 2136 LSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVY 2195 ++ S S TP P T++ +T E I + + +G + Sbjct: 2228 STMPVVTSEASTLSATPVDTSTPVTTSTEAT----SSPTTAEGTSIPTSTLS-EGTTPLT 2282 Query: 2196 KSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL-K 2254 ++ + +NSE+S P+ +N P + P +S TS S+ PL + Sbjct: 2283 SIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342 Query: 2255 TPASK---SPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR 2311 P S + E T +T+P ++ S SQ G S + ST S Sbjct: 2343 MPVSTTMVASFETSTLSTTP--------ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394 Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR 2371 + S P+ + S + +P + + P T+S +S+ ++ G TSP Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVD--TSTPVTTSTEASSSPTTAEGTSIPTSP-- 2450 Query: 2372 QMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR 2431 + T + + + + SE+ G + V+ S +T + S S Sbjct: 2451 --PSEGTTPLASMPVSTTPVVSSEA----------GTLSTTPVDTSTPMTTSTEASSSPT 2498 Query: 2432 SERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDM 2491 + ++V ST + TL + S +P + P + T S SP + Sbjct: 2499 TAEDIVVPIST---ASEGSTLLTSIPVST-----TPVASPEASTLSTTPVDSNSPVVTST 2550 Query: 2492 SLSTHSSVQAGGWRKLPPNLSPTIEYNDG------RPAKRHDIARSHSESPSRLPI---- 2541 +S+ ++ G PT Y++G P +A S + + S P+ Sbjct: 2551 EISSSATSAEG-------TSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603 Query: 2542 --------NRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS--EDEKH 2591 + S T ++ S S+ VST + S++ ASSE+S + + + Sbjct: 2604 PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL 2663 Query: 2592 VNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651 V + +GT S +A+G+ S ST S+ TN S TL+ + Sbjct: 2664 VTTSTGTSSS---PTTAEGS---------SMPTSTPGERSTPLTNILVSTTLLANSEAST 2711 Query: 2652 SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSV 2711 T +P + PV S ++P + + +GS Sbjct: 2712 LST-------------------TPVDTSTPVTTSAEASSSPTTAEGTSMRI-STPSDGST 2751 Query: 2712 PMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS----IVERTPFSSSSS 2767 P+ ++ L S + V A + T + +PV+ + E+S E T +S+ Sbjct: 2752 PLTSI-----LVSTLPV-ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTP 2805 Query: 2768 SKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSG 2827 S+ S+P ++ P N+ P S A + S P TPV +TK S T + E Sbjct: 2806 SETSTPLTSM-----PVNHTP-VASSEAGTLSTTPVDTSTPVTTSTKASSSPT-TAEGIV 2858 Query: 2828 TQSPKRHSGSYLVTSV 2843 GS L+TS+ Sbjct: 2859 VPISTASEGSTLLTSI 2874 Score = 75.9 bits (185), Expect = 5e-13 Identities = 167/765 (21%), Positives = 282/765 (36%), Gaps = 88/765 (11%) Query: 2125 SRQASSDS---DSILSLKSGISLGS-PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKK 2180 S QASS +S KS S GS P P K +S + P E ST T Sbjct: 191 STQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS 250 Query: 2181 IESESKGIKG-GKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNS 2239 ++ S G + S +G + + + + + ++S +IP + ++ Sbjct: 251 AQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310 Query: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTS-PRGAKPSVKSELSPVARQTSQIGGSSKA 2298 +S+SP + +G + T + +EG T TS P P SE+S + S Sbjct: 311 EASSSPTTAEGTSIPT---STYTEGSTPLTSTPASTMPVATSEMSTL----------SIT 357 Query: 2299 PSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKS 2358 P + + +T + P+ P + S +++S G ++ + L +S ST ST Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417 Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSR 2418 S K T+ S + T ++ + S + S ++ + + + Sbjct: 418 VDS-KTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476 Query: 2419 MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQ 2478 + S + ++ S P ++ PS E S S+S S+ P + S+ Sbjct: 477 VDSKTQVTTSTEASSSPPTAEVNSMPTSTPS-------EGSTPLTSMSVSTMPVA--SSE 527 Query: 2479 AQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLS-PTIEYNDG------RPAKRHDIARS 2531 A T LS + D S +S +A P S PT ++G P + S Sbjct: 528 AST--LSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585 Query: 2532 HSESPSRLPINRSGTWKREHSKHSS--------SLPRVSTWRRTG------SSSSILSAS 2577 + + S P + S T+ S+ SS S+P ST+ G S S+ L AS Sbjct: 586 EASTTSTTPAD-SNTFVTTSSEASSSSTTAEGTSMP-TSTYSERGTTITSMSVSTTLVAS 643 Query: 2578 SESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG 2637 SE+S + + + + ++ + ++ + +A+GT T TS V++ Sbjct: 644 SEASTLSTTPVDSN-TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702 Query: 2638 AESKTL----IYQMAPAVSKTE----DVWVRIEDCPINNPRSGRSP-----------TGN 2678 +E+ TL + P + TE P + P G +P T + Sbjct: 703 SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762 Query: 2679 TPPVIDSVSEKANPNIKDSKDNQAKQNVGNG-SVPMRTVGLENRLNSFIQVDAPDQKGTE 2737 + + + +I S + G S+P+ T + L + I V E Sbjct: 763 EASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE 822 Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKH--SSPSGTVAARVTPFNYNPSP----R 2791 PV + S + T SSS + S P+ T + TP P Sbjct: 823 ASTLSTTPV----DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878 Query: 2792 KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSG 2836 S+ + S P TPV N+T+ R S T S GT P G Sbjct: 879 TSAISTLSTTPVDTSTPVTNSTEARSS---PTTSEGTSMPTSTPG 920 Score = 72.0 bits (175), Expect = 8e-12 Identities = 315/1667 (18%), Positives = 557/1667 (33%), Gaps = 203/1667 (12%) Query: 1211 MSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPIC 1270 +++S+E +S+P++ + S S S +T V+S T+ T V+ + Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLV 2664 Query: 1271 FSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHP 1330 + + SS ++AE T+ + + L + + S +S P + P Sbjct: 2665 TTSTGTSSSPTTAEGS--SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP 2722 Query: 1331 RTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSV 1390 T S+ S ++E + S G+ TP + V P+ S ++V Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGS---------TPLT--SILVSTLPVASSEASTV 2771 Query: 1391 SSLDSFESRSIASSVQ--SEPCSGMVSGIISPSDLPD---SPGQTMPPSRSKTPPPPPQT 1445 S+ S + +S + S P + V+ + P+ P +P +MP + + T Sbjct: 2772 STTAVDTSIPVTTSTEASSSPTTAEVTSM--PTSTPSETSTPLTSMPVNHTPVASSEAGT 2829 Query: 1446 AQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLL-HFATESTPDGFSCSS 1504 T T+ K S P A V + + TLL +TP S +S Sbjct: 2830 LSTTPVDTSTPVTTSTKASSSPTTA--EGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887 Query: 1505 SLSALSLDEPF-IQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTID---SE 1560 +LS +D + E P E G P E + T+ SE Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAE---GTSMPISTPSEVSTPLTSILVSTVPVAGSE 2944 Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620 L + D + P +S +A TA P++ P + P Sbjct: 2945 ASTLSTTPVD----------TRTPVTTSAEASSSPTTAEGTSMPIST-----PGERRTPL 2989 Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 + V+ + + R TP+ ST S S T E G G+ Sbjct: 2990 TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE--------GTGIP---- 3037 Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 + P+EG + + T+ V IPE D S+ P Sbjct: 3038 -------ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD--------------SNSP 3076 Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP-QNTEYRTRVRKNADSKNNL 1799 + + +S P +G PV P ++ T D+ + Sbjct: 3077 VVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV 3136 Query: 1800 NAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAF---DSPHHYTPIEGTPYCF 1856 + + + S P V DS TP++ + Sbjct: 3137 TTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVT 3196 Query: 1857 SRNDSLSSLDFDDDDVDLSREKAELRKAKENK-------ESEAKVTSHTELTSNQQSANK 1909 + ++ SS + + S + SEA + S T + SN Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256 Query: 1910 TQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSL 1969 T+A + P G P P G+ L + + T V S S+L Sbjct: 3257 TEASSSPPTAEGTSMP------------TSTPSEGST---PLTSMPVSTTTVASSETSTL 3301 Query: 1970 SSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRNSSLS 2028 S+ ++ D P+ + G P + TPV S S+LS Sbjct: 3302 STTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLS 3361 Query: 2029 SLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDS 2088 + +D+ ++++ P+ +G + S + G + + + Sbjct: 3362 TTPVDTSTP-----VTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV----- 3411 Query: 2089 EHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPF 2148 SE +N++V++ +A+++ ++ S + + + +S+ P Sbjct: 3412 -----VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI-MPL 3465 Query: 2149 HLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRS-NS 2207 TP + E STL T +++ S + S T +V S + Sbjct: 3466 STTP---------------VASSEASTLSTTPVDT-STPVTTSSPTNSSPTTAEVTSMPT 3509 Query: 2208 EISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPV-SKKGPPLKTPASKSPSEGQT 2266 +G+ PL NMP + + S+ ST+PV S + AS SP+ Q Sbjct: 3510 STAGEGSTPL-TNMPV-----STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ- 3562 Query: 2267 ATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGR 2326 T+ R + PS S + T+ + S+ S S STPS P++ QS Sbjct: 3563 -VTTMRMSTPSEGS-----SSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQS--- 3613 Query: 2327 NSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSK 2386 NS I+ P +S S+P T S+ S +S + T ++ Sbjct: 3614 NSTPTPPEVITLP--MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671 Query: 2387 NASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKE 2446 +SS E + + + G + + +S+T+ + SE P +V + Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEG---STPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTS 3728 Query: 2447 APSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL------SPSLPDMSLSTHSSVQ 2500 + + L+ + S+ T + TPV +PS+P + S + Sbjct: 3729 TEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTA 3788 Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESP-SRLPINRSGTWKREHSKHSSSLP 2559 + G P L T ++R + + SP S + + + T S+ L Sbjct: 3789 SEG-SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPL- 3846 Query: 2560 RVSTWRRTGSSSSILSAS----SESSEKAKSEDEKHVN-----SISGTKQSKENQVSAKG 2610 T + GS S + S +SE++ V+ S G + + Sbjct: 3847 --LTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTST 3904 Query: 2611 TWRKIKENEFSPTNSTSQTVS-SGATNGAESKTLIY-QMAPAVSKTEDVWVRIEDCPINN 2668 T+ + +PT + T+S S T G+ T I+ P S T DV+ Sbjct: 3905 TFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVF---------- 3954 Query: 2669 PRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728 + TG + + +E P+ S + + P T L Sbjct: 3955 ----PATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP--LTYVTMS 4008 Query: 2729 DAPDQKGTEIKPGQNNPVPVSETN----ESSIVERTPFSSSSSSKHSSPSGTVAARVTPF 2784 AP T + + +S T+ +S+ R SS SS+ S+ + P Sbjct: 4009 TAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPP 4068 Query: 2785 NYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 ++ +P +SA ST+ P + T + TK T + T P Sbjct: 4069 AHSSTPPTTSASSTTVNPEAV-TTMTTRTKPSTRTTSFPTVTTTAVP 4114 Score = 65.1 bits (157), Expect = 1e-09 Identities = 205/1025 (20%), Positives = 347/1025 (33%), Gaps = 154/1025 (15%) Query: 1898 TELTSNQQSANKTQAIAKQPINRGQPKPI----LQKQSTFPQSSKDIPDRGAATDEKLQN 1953 T LTS S T +A ++ P+ L ST P S +P AT Sbjct: 334 TPLTSTPAS---TMPVATSEMSTLSITPVDTSTLVTTSTEPSS---LPTTAEATSMLTST 387 Query: 1954 FAIENTPVC---------FSHNSSLSSLSDIDQEN--NNKENEPIKETEPPDSQGEPSKP 2002 + +TP+ S +S +S +D + T D+ S P Sbjct: 388 LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447 Query: 2003 QASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKK--------PS 2054 S V TPV S S+LS+ +DS+ + +S+ P + PS Sbjct: 448 SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507 Query: 2055 RLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPD--------SEHGLSPDSENFDWKAIQE 2106 S M E TL + S +P+ + E Sbjct: 508 EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSE 567 Query: 2107 GA----NSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGS--------PFHLTPDQ 2154 G+ N VS+ ++ A + +DS++ ++ S S S P ++ Sbjct: 568 GSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSER 627 Query: 2155 EEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGK---VRSNSEISG 2211 + + ++ E STL T ++S + + + S T + + +++ G Sbjct: 628 GTTITSMSVSTTLVASSEASTLSTTPVDSNTP-VTTSTEATSSSTTAEGTSMPTSTYTEG 686 Query: 2212 Q---MKQPLQANMPSISRGRTM------IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPS 2262 P+ + + S T+ P ++ +S+SP + G + T +PS Sbjct: 687 STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT---STPS 743 Query: 2263 EGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQ 2322 EG T TS +K + S + T + S S T + P+S P + Sbjct: 744 EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE 803 Query: 2323 -SPGRNSISPGRNGISPP--NKLSQLP-RTSSPSTASTK-SSGSGKMSYTSPGRQMSQQN 2377 SP SI ++ P + LS P ++SP T ST+ SS TS + Sbjct: 804 GSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG 863 Query: 2378 LTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL 2437 T T + + + + S ++ ++ E +R S T S G+ S Sbjct: 864 RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE-ARSSPTTSEGTSMPTSTPGEG 922 Query: 2438 VRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHS 2497 T + ++ +P +S +R S T TPV + + +T S Sbjct: 923 STPLTSMPDSTTPV-------------VSSEARTLSATPVDTSTPVTT-----STEATSS 964 Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPI--NRSGTWKREHSKHS 2555 A G S P +A S + + S P+ N T E S Sbjct: 965 PTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024 Query: 2556 SSLPRVSTWRRTGSS----------SSILSASSESSEKAKSEDEKHVNSISGTKQSKENQ 2605 + S T S S+ + ASSE+S + + + ++ Q+ + Sbjct: 1025 PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS-TPVTTYSQASSSS 1083 Query: 2606 VSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCP 2665 +A GT T TS VS+ +E+ TL Sbjct: 1084 TTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTL---------------------- 1121 Query: 2666 INNPRSGRSPTGNTPPVIDSVSEKANPNIKDS----KDNQAKQNVGNGSVPMRT---VGL 2718 +P + PV S ++P + ++ S+P+ T V Sbjct: 1122 ------STTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSS 1175 Query: 2719 ENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVA 2778 E S VD+ Q T + ++P P +E T +S+ + S+P ++ Sbjct: 1176 EANTLSTTPVDSKTQVATSTE--ASSPPPTAEV--------TSMPTSTPGERSTPLTSMP 1225 Query: 2779 ARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838 R TP S A + S P TPV + + S T + E + + GS Sbjct: 1226 VRHTPV------ASSEASTLSTSPVDTSTPVTTSAETSSSPT-TAEGTSLPTSTTSEGST 1278 Query: 2839 LVTSV 2843 L+TS+ Sbjct: 1279 LLTSI 1283 Score = 61.2 bits (147), Expect = 1e-08 Identities = 286/1599 (17%), Positives = 542/1599 (33%), Gaps = 171/1599 (10%) Query: 1171 RHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKT--EHMSSSSENTSTPSSNAKRQ 1228 + PI + +T + S + + S + S T + + + +T T SS + Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAE 2678 Query: 1229 NQLHPSSAQSRSGQPQK---AATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAED 1285 P+S P +T +++ T+ T V+ + + + SS ++AE Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAE- 2737 Query: 1286 EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQH-PRTKSSRLQGSSLSS 1344 G + +T + + + S+E AV P T S+ S ++ Sbjct: 2738 --GTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795 Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404 E S +PS++ P H TP+ S ++S+ S + +S Sbjct: 2796 EVT-------SMPTSTPSETSTPLTSMPVNH----TPVASSEAGTLSTTPVDTSTPVTTS 2844 Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA-PTAEKR 1463 ++ GI+ P + T P A T P + + P Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTST 2904 Query: 1464 ESGPKQAAVNAAVQRVQVLPDADT-LLHFATESTPDGFSCSSSLSALSLD-EPFIQKDVE 1521 E + + T L + P S +S+LS +D + E Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964 Query: 1522 LRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSD-DDDIEILEECII 1580 P E + + + + + SE L + D + Sbjct: 2965 ASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA 3024 Query: 1581 SAMPTKSSRKA---KKPAQTASKLPP-PVARKPSQLPVYKLL-----PSQNRLQPQKHVS 1631 S+ PT + P++ ++ L PV+ P +P L S + + VS Sbjct: 3025 SSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVS 3084 Query: 1632 FTP----GDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEGVRGGAQS 1681 +P G MP EG+ P++ + TS + T+ + P + + Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV-------- 3136 Query: 1682 GEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPF 1741 T TE S+ G + + P + + S+ S P Sbjct: 3137 -------TTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPV 3189 Query: 1742 RVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNA 1801 + +A++S++A + + +P+ +P + + S +++ Sbjct: 3190 DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDS 3249 Query: 1802 ERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDS 1861 + + ++ P+ GS +P P+ T S + Sbjct: 3250 NTPLTTSTEASSSPPTAEGTSMPTSTPS-----EGS----TPLTSMPVSTTTVASSETST 3300 Query: 1862 LSSLDFDDDDVDLSREKAELRKAKENKESEAKVT---SHTELTSNQQS-----ANKTQAI 1913 LS+ D + +A + S T T LT+ S +++ + Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360 Query: 1914 AKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDE---KLQNFAIENTPVCFSHNSSLS 1970 + P++ P + S P +++ ++ E L + + TPV +S ++ Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVV---SSEVN 3417 Query: 1971 SLSDIDQENNNKENEPIKETEPP---DSQGEPSKPQASGYAPKS-FHVEDTPVCFSRNSS 2026 +LS ++N + + P + P+ + G P S + TPV S S+ Sbjct: 3418 TLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST 3477 Query: 2027 LSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRP 2086 LS+ +D+ ++++ P P+ + + S G ++ + + Sbjct: 3478 LSTTPVDTSTP-----VTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPV--- 3529 Query: 2087 DSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAAC----LSRQASSDSDSILSLKSGI 2142 SE +N+ V+S QA+++ + + S+ S+ SL + Sbjct: 3530 -------ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT-- 3580 Query: 2143 SLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGK 2202 L S ++T + P T + ++ST T +S S +IT Sbjct: 3581 MLLSSTYVTSSEASTPSTPSV--------DRSTPVTTSTQSNS------TPTPPEVITLP 3626 Query: 2203 VRSNSEISGQMK-QPLQANMPSISRGRTMIHI------PGVRNSSSSTSPVSKKGPPLKT 2255 + + SE+S + P+ +IS T + P + ++ S+SPV+ +G T Sbjct: 3627 MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG---TT 3683 Query: 2256 PASKSPSEGQT-ATTSPRGAKPSVKSELS----PVARQTSQIGGSSKAPSRSGSRDSTPS 2310 +PSEG T TT P SE S P ++ + S++A S S + DST Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST-- 3741 Query: 2311 RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS--------TKSSGSG 2362 +S P++ + G + +++ P +S+PS S T S GS Sbjct: 3742 ---TMSVSMPMEIS-----TLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSS 3793 Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSST 2422 + M ++++ L P S + + ++ G ++ST Sbjct: 3794 SPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG---DTSTPLLTST 3850 Query: 2423 KSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPA-------SPT 2475 K +GS S +E + T + P TL SF S +S P +P+ Sbjct: 3851 K-AGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPS 3909 Query: 2476 RSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSES 2535 A TP + P +S+S + G P+ T D PA ++ S Sbjct: 3910 TDTASTPTI-PVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968 Query: 2536 PSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSI 2595 +N T + S+ +T T ++ S + ++ S Sbjct: 3969 TE---LNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSA 4025 Query: 2596 SGTKQSKENQVSAKGTWRKIKENEFS--PTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653 S + S T R + + S P+ TS T+ A S T A + + Sbjct: 4026 STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPP-TFPPAHSSTPPTTSASSTTV 4084 Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANP 2692 + + + R+ PT T V + + K+NP Sbjct: 4085 NPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNP 4123 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 73.2 bits (178), Expect = 4e-12 Identities = 108/511 (21%), Positives = 184/511 (36%), Gaps = 51/511 (9%) Query: 2218 QANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPS 2277 ++ P R R+ + G SSSS+S + PP K P S +T SP + P Sbjct: 340 RSRSPVRRRRRSSASLSG---SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR 396 Query: 2278 VKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN-GI 2336 + SP A P TP + + SR SPGR S ++ G Sbjct: 397 RRHRPSPPA-----------TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445 Query: 2337 SPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSES 2396 S P+ + ++ GKM+ +Q Q Q S + SS + Sbjct: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505 Query: 2397 ASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD--------RSERPVLVRQSTFIKEAP 2448 K + N G ++ SR +S + + RS P R+ AP Sbjct: 506 RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP 565 Query: 2449 SPTLRRKLEESASFESLSPSSRPASPTRSQAQTPV---LSPSLPDMSLSTHSSVQAGGWR 2505 P RR + SP R SP+ + P+ SPS P + +S R Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT--ASPPPPPKR 623 Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT---------WKREHSKHSS 2556 + P+ P + P K+ + SPS +R G+ + +K S Sbjct: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683 Query: 2557 SLPRVSTWRRTGSSSSILSASSESSEK--AKSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614 PR + + S + +S S ++ + S + + +S T + K+ + +A + + Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743 Query: 2615 IKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS 2674 ++ S + S S + A + + +P+ + + V V + +S Sbjct: 744 VR--RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV----------KKAKS 791 Query: 2675 PTGNTPPVIDSVSEKANPNIKDSKDNQAKQN 2705 PT + P +S E K KD + K++ Sbjct: 792 PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822 Score = 62.0 bits (149), Expect = 8e-09 Identities = 148/705 (20%), Positives = 239/705 (33%), Gaps = 57/705 (8%) Query: 2153 DQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQ 2212 D+EEK + K R P + + S + K+ + + +S S Sbjct: 155 DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP 214 Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPR 2272 K+ +P S + P V+ ++S TS + K P P K PS + + Sbjct: 215 EKKEKTPELPEPS---VKVKEPSVQEATS-TSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270 Query: 2273 GAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR-----PAQQPLSRPIQSPGRN 2327 K +S +R S+ S++PS + R SR P ++P R SP R Sbjct: 271 KEKTRPRSR----SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326 Query: 2328 SISPGRNGISPPNKLSQLP----RTSSPSTASTKSSGSGKMSYTSPGR--QMSQQNLTKQ 2381 + P R P ++ S+ P R SS S + + SS S S + P + + + K Sbjct: 327 T-PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385 Query: 2382 TGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQS 2441 LS +AS R S + + +R ++ S S R+ V + Sbjct: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG-RTSGKVTKHKG 444 Query: 2442 TFIKEAPSPTLR-RKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQ 2500 T +E+PSP + RK+E S S E A + + Q + S S+ SS Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504 Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHS-------- 2552 P S GR +RH +RS S SP + S +R S Sbjct: 505 E------RPKRSHVKNGEVGR-RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557 Query: 2553 KHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTW 2612 + S S RRT + S + ++ I + Sbjct: 558 RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617 Query: 2613 RKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672 + SP+ + VS S + + +P++S R P + R Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH----RKGSSPSRSTREA 673 Query: 2673 RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPD 2732 RSP N S P + + G S P R +V Sbjct: 674 RSPQPN-----KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP 728 Query: 2733 QKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK 2792 + K +P V + S V +P ++ K +P V ++ N++P+ Sbjct: 729 EPKKIKKAASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786 Query: 2793 SSADSTSARPSQIPTPVNNNT-----KKRDSKTDSTESSGTQSPK 2832 A S P+ P+P N+ KK+ K D + K Sbjct: 787 KKAKS----PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKK 827 Score = 46.6 bits (109), Expect = 4e-04 Identities = 60/251 (23%), Positives = 91/251 (36%), Gaps = 24/251 (9%) Query: 2234 PGVRNSSSSTSPVSKKG--PPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQ 2291 P + S S S +KG P T ++SP + + SPR P S PV R Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR---- 702 Query: 2292 IGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSP 2351 G+S +P R S PS P+ +P+ R ++P I + SP + + R SS Sbjct: 703 --GASSSPQRRQS----PS-PSTRPIRRVSRTPEPKKI---KKAASPSPQ--SVRRVSSS 750 Query: 2352 STASTKSSGSGKMSYTSPGRQMSQQNLTKQTGL--SKNASSIPRSESASKGLNQMNNGNG 2409 + S + K P SQ T + K A S S S + +Q G Sbjct: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKK 810 Query: 2410 ANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS 2469 KK + K + + E+ V + + A L + E + Sbjct: 811 KKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQ----EEPVAAP 866 Query: 2470 RPASPTRSQAQ 2480 P T S+A+ Sbjct: 867 EPKKETESEAE 877 Score = 38.5 bits (88), Expect = 0.096 Identities = 99/477 (20%), Positives = 157/477 (32%), Gaps = 65/477 (13%) Query: 1207 KTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVED 1266 K + + SS KR+ P +SRS P++ + S + +E +++ Sbjct: 146 KQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR----RSSPVRRERKRSHSRSP 201 Query: 1267 TPICFSRCSS-----------LSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRS 1315 SR S L S E + T +D + I E Sbjct: 202 RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP 261 Query: 1316 AEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPK----- 1370 ++ E PR++S S S S H ++S S S + P Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321 Query: 1371 ------------SPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP--------C 1410 PP H +P+ R +S +SL S S +S +S P Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS-ASLSGSSSSSSSSRSRSPPKKPPKRTSS 380 Query: 1411 SGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ---TAQTKREVPKNKAPTAEKRESGP 1467 + +SPS P P + PS TPPP + T Q K++ + R SG Sbjct: 381 PPRKTRRLSPSASP--PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG- 437 Query: 1468 KQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPP 1527 K +R P +ES D ++ + +Q+ + R Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS-------VQQRRQYRRQNQ 490 Query: 1528 VQENDNG--NETESEQPKESNENQEKEAEKTIDSEKDLLDDS-----DDDDIEILEECII 1580 +D+G + +E E+PK S+ + + S S + Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550 Query: 1581 SAMPTKSSRK---AKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTP 1634 S PT+ R A P + + PPP R PS P + PS R P ++P Sbjct: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP-PPRRRSPSPRRYSPPIQRRYSP 606 Score = 32.3 bits (72), Expect = 6.9 Identities = 42/202 (20%), Positives = 73/202 (36%), Gaps = 17/202 (8%) Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378 P P+ R+ S R + + + + + P +P PP+ V Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636 Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438 +P R + V+ S S+ S+ G SPS ++ P++ + Sbjct: 637 HSPPPKQRSSPVTKRRS-------PSLSSKHRKGS-----SPSR-STREARSPQPNKRHS 683 Query: 1439 PPPPPQTAQTKREVP--KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496 P P P+ QT P + A ++ +R P + ++RV P+ + A+ S Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS--TRPIRRVSRTPEPKKIKKAASPSP 741 Query: 1497 PDGFSCSSSLSALSLDEPFIQK 1518 SSS S EP +K Sbjct: 742 QSVRRVSSSRSVSGSPEPAAKK 763 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 71.2 bits (173), Expect = 1e-11 Identities = 164/762 (21%), Positives = 273/762 (35%), Gaps = 95/762 (12%) Query: 2113 SSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGE 2172 SS + A S ++D SLKS S L P KP TS ++ P Sbjct: 7 SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPT---KPATSRNS--VMSPSS 61 Query: 2173 -KSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI------- 2224 KST T +K + +S + K R+ S +S + + + Sbjct: 62 SKSTKSTS-----TKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRG 116 Query: 2225 --SRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSEL 2282 SRGRT PG R S SS K+ P S++ + G+ T GA+P + S + Sbjct: 117 THSRGRT----PGRRGSRSS-----KRSP------SRASTPGRIRT---HGARPGMASRV 158 Query: 2283 SPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSP------GRNS---ISPGR 2333 Q G S R+ +R+ + S+P LS+ P GR+S ++P Sbjct: 159 RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN--LSKKSYRPPGGSGIGRSSELAVTPST 216 Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGS-GKMSYTSPGRQMSQQNLTKQTGLSKNASSIP 2392 P + ++ +PS +S++ S G+M S + S ++ + AS+ Sbjct: 217 AKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS 276 Query: 2393 RSESASKGLNQMNNGNGANKKVELS-RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPT 2451 R +S S+ + + +G+ K+ R S K + S + R ++ Q Sbjct: 277 RPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMG--------- 327 Query: 2452 LRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNL 2511 + +S S ++ +P R ++ +PS + SS + R Sbjct: 328 ---RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384 Query: 2512 SPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSS 2571 + G P K+ D +RS S + +R +K S S + R S Sbjct: 385 KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA---RDCSRSR 441 Query: 2572 SILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVS 2631 S A S ++ ++ H S S K ++ + KE + S S S+ Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS-----KERDHSQLGSPSKERD 496 Query: 2632 SGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691 + + SK + + + SK D R RSP S S Sbjct: 497 HRRSR-SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS-QSRSPSEE 554 Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSET 2751 + S+ +++ P + +S + D + + G + P S+ Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614 Query: 2752 NESSIVERTPFS------SSSSSKHSSPSGTVA----------ARVTPFNYNPSPRKSSA 2795 S RTP S +SSK S PS + R + + N +P K+S+ Sbjct: 615 KAHSR-SRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673 Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 S S PS + DS+ D+T S T +R S S Sbjct: 674 HSPSTFPSG-----GQTLSQDDSQADATTSKATLPGERSSSS 710 Score = 58.2 bits (139), Expect = 1e-07 Identities = 107/427 (25%), Positives = 164/427 (38%), Gaps = 58/427 (13%) Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT-----PA---------S 2258 M P +++ PS+S + +P ++ +K P ++ PA S Sbjct: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60 Query: 2259 KSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLS 2318 S S T+T +PS +S + AR S++ ++ S + D + Sbjct: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASD------VRCHQR 114 Query: 2319 RPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNL 2378 R S GR +PGR G S +K S R S+P T + G S + + Sbjct: 115 RGTHSRGR---TPGRRG-SRSSKRSP-SRASTPGRIRTHGARPGMASRVRTPTSQQKGSR 169 Query: 2379 TKQTGLSKNASSIPRSESASKGLNQMN----NGNGANKKVELSRMSST------------ 2422 K G + S+ RS+S + L++ + G+G + EL+ ST Sbjct: 170 GKSYGRPR-TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSK 228 Query: 2423 KSSGSESDRSERPVLVRQSTFI---KEAPSPTLRRKLEESASFESLSPSSRPASPTRSQA 2479 + S + S S R V I +++ SPT S+ S SRP S SQ+ Sbjct: 229 EKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT--EMSSRVKSYNQASTRSRPQS--HSQS 284 Query: 2480 QTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSH----SES 2535 ++P S S THS V++ W++ RH +RSH S++ Sbjct: 285 RSPRRSRS--GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN 342 Query: 2536 PSRLP-INRSGTWKREHSK-HSSSLPRVSTWRRT-GSSSSILSASSESSEKAKSEDEKHV 2592 SR P RS W R SK S S R S+ R SSS S S + ++ H Sbjct: 343 QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS 402 Query: 2593 NSISGTK 2599 S S K Sbjct: 403 RSRSPNK 409 Score = 53.9 bits (128), Expect = 2e-06 Identities = 82/333 (24%), Positives = 131/333 (39%), Gaps = 47/333 (14%) Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIP-GVRNSSSSTSP-----VSKKGPPLKT-- 2255 RS S + + ++ P+ +R R+ P R+ S S SP S+ P K Sbjct: 389 RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARD 448 Query: 2256 -PASKSPSEGQ--TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRP 2312 S+SP++ + + + SP A+ +S R SQ+G SK SR + R Sbjct: 449 RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508 Query: 2313 AQQPLSRPIQSPGRNSISPG----RNGISPPNKLSQLPRTSSPS------TASTKSSGSG 2362 +Q S + R S SP R PNK ++ SPS + + S Sbjct: 509 CRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD 568 Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMN-----NGNGANKKVELS 2417 + + SP ++ ++ +SS R S S+ N+ + + K S Sbjct: 569 RRRWRSPSKERERR--------QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS 620 Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAP----SPTLRRKLEES---ASFESLSPSSR 2470 R S + + S+S S + QST + +P SPT L ++ + S SPS+ Sbjct: 621 RTPSKEGNHSQSRTSSKESDPSQST-VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTF 679 Query: 2471 PA-----SPTRSQAQTPVLSPSLPDMSLSTHSS 2498 P+ S SQA +LP S+ SS Sbjct: 680 PSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712 Score = 41.2 bits (95), Expect = 0.015 Identities = 118/684 (17%), Positives = 257/684 (37%), Gaps = 66/684 (9%) Query: 722 SAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKA------LEAELDAQHLSETFDN 775 SA R+L+ +PA +++ +MSP SS + ++A + + ++ + + + Sbjct: 37 SATPNRSLVPTKPATSRNS-VMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVS 95 Query: 776 IDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTV--------LSPYLN 827 D + KAS S R Q T +RS + + P + Sbjct: 96 TDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMA 155 Query: 828 TTVLPSSSSSRGSLDSS-----RSEKDRSLERERGIGLGNYHP-ATENPGTSSKRGLQIS 881 + V +S +GS S S ++RS + R + +Y P G SS+ + S Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215 Query: 882 TTAAQI-----AKVMEEVSAIHTSQEDRSSG-----STTELHCVTDERNALRRSSAAHTH 931 T Q +K + + +S++ +S G S + + T+ + ++ + A T Sbjct: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275 Query: 932 SNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDE 991 S + ++S + R+ S + + S+ + S + ++G + + Sbjct: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG----ILSQMGRHSQ 331 Query: 992 SKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWAR 1051 S+ S G+ +H + + ++S S E+ + G SP + ++ Sbjct: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391 Query: 1052 P--KHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQ--ECVSPYRSRGA 1107 + D + ++R++S + Y D+ P+ + SPY++R Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPY--KARDRSRSRSPNKARDCSRSRSPYKARDR 449 Query: 1108 NGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYN 1167 + S + +H +++ +++ + K ++S+ S ++ + + + Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC 509 Query: 1168 EEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR 1227 + R + D+ + ++QS S +K S++ + +PS R Sbjct: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569 Query: 1228 QNQLHPSS----AQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSA 1283 + PS QSRS ++ + S Q +SR +S+ Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG------------YSR-----PRASS 612 Query: 1284 EDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLS 1343 +++ T + ++ KE ++S V P + P T++S L + Sbjct: 613 KEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST---VPRSPDWKRSP-TRTSSLSQNRTP 668 Query: 1344 SESARHKAVEFSSGAKSPSKSGAQ 1367 S+++ H F SG ++ S+ +Q Sbjct: 669 SKTSSHSPSTFPSGGQTLSQDDSQ 692 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 70.9 bits (172), Expect = 2e-11 Identities = 97/421 (23%), Positives = 165/421 (39%), Gaps = 35/421 (8%) Query: 2224 ISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 IS G + G +SS S + G + + + + TTS G + SE S Sbjct: 38 ISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSS-GISTATNSEFS 96 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343 V+ S S + + SG+ +T S + P S + +S + + N S Sbjct: 97 TVSSGISIATNSESSTTSSGASTATNSE-SSTPSSGASTATNSDSSTTSSGASTATN--S 153 Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ 2403 TSS ++ +T S S S S ++ + + N+ S S AS N Sbjct: 154 DSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS 213 Query: 2404 MNN--GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESAS 2461 + NGA S S+T S S + SE + + S T + + Sbjct: 214 ESRTTSNGAGTATN-SESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATN 272 Query: 2462 FESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGR 2521 ES + SS ++ T S++ TP S + + ++ SS + G + T +D Sbjct: 273 SESSTVSSGISTVTNSESSTP---SSGANTATNSESSTTSSG--------ANTATNSDSS 321 Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581 ++SES + SG +S+ S++ ST +GSS++ S + Sbjct: 322 TTSSGASTATNSESST----TSSGASTATNSESSTTSSGASTATNSGSSTT-----SSGT 372 Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK 2641 A + + V+S + T + E+ ++ G + TNS S TVSSGA+ S+ Sbjct: 373 STATNSESSTVSSGASTATTSESSTTSSGA--------STATNSESSTVSSGASTATNSE 424 Query: 2642 T 2642 + Sbjct: 425 S 425 Score = 64.3 bits (155), Expect = 2e-09 Identities = 90/414 (21%), Positives = 153/414 (36%), Gaps = 34/414 (8%) Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289 ++H+ NS+ +++ + + + AS + + G + T+S G + S S + Sbjct: 15 LLHLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSS--GVSTATISGSSVTSNGV 72 Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 S + S + SG +T S S +GIS S+ TS Sbjct: 73 SIVTNSEFHTTSSGISTATNSE-----------------FSTVSSGISIATN-SESSTTS 114 Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409 S ++ +T S S S S + + N+ S S AS N ++ Sbjct: 115 SGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTS 174 Query: 2410 ANKKVELSRMSSTKSS-GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPS 2468 + + SST SS S + SE ++ + S T + + ES + S Sbjct: 175 SGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTS 234 Query: 2469 SRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI 2528 S ++ T S++ TP S S+ +S AG + T + + + Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAG---------TATNSESSTVSSGISTV 285 Query: 2529 ARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588 S S +PS + E S SS + + +SS +A++ S S Sbjct: 286 TNSESSTPSS---GANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGA 342 Query: 2589 EKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKT 2642 NS S T S + + G+ + TNS S TVSSGA+ S++ Sbjct: 343 STATNSESSTTSSGASTATNSGS-STTSSGTSTATNSESSTVSSGASTATTSES 395 Score = 60.5 bits (145), Expect = 2e-08 Identities = 98/503 (19%), Positives = 181/503 (35%), Gaps = 76/503 (15%) Query: 2348 TSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNG 2407 T+S T+++ ++GS S S G + + + T + ++I S S G++ + N Sbjct: 22 TNSNETSTSANTGS---SVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTN- 77 Query: 2408 NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSP 2467 S +T S S + SE + + + S T + + ES +P Sbjct: 78 ---------SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTP 128 Query: 2468 SSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHD 2527 SS ++ T S + T S S S+ +S +A Sbjct: 129 SSGASTATNSDSSTTSSGASTATNSDSSTTSSEAS------------------------- 163 Query: 2528 IARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSE 2587 ++SES + SG +S+ S+ R ST +++S S +S + A + Sbjct: 164 -TATNSESST----TSSGASTATNSESSTVSSRAST-----ATNSESSTTSSGASTATNS 213 Query: 2588 DEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSP-------TNSTSQTVSSGATNGAES 2640 + + ++ +GT + E+ ++ G +P TNS S T SSGA S Sbjct: 214 ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273 Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700 ++ S + + + P SG + N+ S N S + Sbjct: 274 ES---------STVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTS 324 Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 N + G NS + G + S T+ ++ E + Sbjct: 325 SGASTATNSESSTTSSGASTATNS---ESSTTSSGASTATNSGSSTTSSGTSTATNSESS 381 Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820 SS +S+ +S S T ++ + + S SS ST+ N+ + S Sbjct: 382 TVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTAT---------NSESSTTSSGA 432 Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843 ++ +SG+ SG+ +T + Sbjct: 433 NTATNSGSSVTSAGSGTAALTGM 455 Score = 49.3 bits (116), Expect = 5e-05 Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 11/348 (3%) Query: 1167 NEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK 1226 N E V I + + SS + + S+SS+ S + +S S TS+ +S A Sbjct: 92 NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTAT 151 Query: 1227 RQNQLHPSSAQSRSGQPQKAATCK-VSSINQETIQTYCVEDTPICFSRCSSLSSLSSAED 1285 + SS S + + + T S+ T + S S+ SS +S Sbjct: 152 NSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 211 Query: 1286 EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSE 1345 T+ A +A + + G +A + S P+ T S SS + Sbjct: 212 NSESRTTSNGAGTATNSESSTTSS--GASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269 Query: 1346 SARHKAVEFSSGAKSPSKSGAQTPKSPPEHYV-QETPLMFSRCTSVSSLDSFESRSIAS- 1403 + ++ SSG + + S + TP S E+ S + ++ DS + S AS Sbjct: 270 ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST 329 Query: 1404 ---SVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTA-QTKREVPKNKAPT 1459 S S SG + S S S T S S T TA ++ + A T Sbjct: 330 ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389 Query: 1460 AEKRESGPKQAAVNAAV--QRVQVLPDADTLLHFATESTPDGFSCSSS 1505 A ES + + A + V A T + + +T G + +++ Sbjct: 390 ATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATN 437 Score = 41.6 bits (96), Expect = 0.011 Identities = 82/382 (21%), Positives = 131/382 (34%), Gaps = 52/382 (13%) Query: 2104 IQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNK 2163 I NS S+ A+ A S ++ S + + S S S T + TS+ Sbjct: 102 ISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSS- 160 Query: 2164 GPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRS--NSEISGQMKQPLQANM 2221 E ST + + S G S ++ + + NSE S A+ Sbjct: 161 --------EASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG---AST 209 Query: 2222 PSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTAT-----TSPRGAKP 2276 + S RT + G +S S++ S + +S S TAT T+ GA Sbjct: 210 ATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269 Query: 2277 SVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI 2336 + SE S V+ S + S + SG+ +T S + S + + S +G Sbjct: 270 ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT--SSGANTATNSDSSTTSSGA 327 Query: 2337 SPPNKLSQLPRTSSPSTASTKSSG---SGKMSYTSPGRQMSQQNLTKQTG-----LSKNA 2388 S +S STA+ S SG + T+ G + + T +S A Sbjct: 328 STATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387 Query: 2389 SSIPRSESA-----------------SKGLNQMNNG------NGANKKVELSRMSSTKSS 2425 S+ SES+ S G + N +GAN ++ S Sbjct: 388 STATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGS 447 Query: 2426 GSESDRSERPVLVRQSTFIKEA 2447 G+ + ST + EA Sbjct: 448 GTAALTGMHTTSHSASTAVSEA 469 Score = 40.4 bits (93), Expect = 0.025 Identities = 71/339 (20%), Positives = 121/339 (35%), Gaps = 16/339 (4%) Query: 2109 NSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRIL 2168 NS S+ A+ A S +++ S++ + S S S T E S++ Sbjct: 137 NSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT 196 Query: 2169 KPGEKSTLE--TKKIESESKGIKGGKKVY---KSLITGKVRSNSEISGQMKQPLQANMPS 2223 +T + SES+ G +S T S + S A + Sbjct: 197 NSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTAT 256 Query: 2224 ISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 S T G +S S S VS + S +PS G T+ ++ S S + Sbjct: 257 NSESSTTSSGAGTATNSES-STVSSGISTVTNSESSTPSSGANTATN---SESSTTSSGA 312 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343 A + SS A + + S ST S A + + + + +G S + + Sbjct: 313 NTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGT 372 Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESA--SKGL 2401 S ST S+ +S + ++ S ++ + +S AS+ SES+ S G Sbjct: 373 STATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGA 432 Query: 2402 NQMNNG-----NGANKKVELSRMSSTKSSGSESDRSERP 2435 N N + + L+ M +T S S + +P Sbjct: 433 NTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471 Score = 36.2 bits (82), Expect = 0.47 Identities = 56/274 (20%), Positives = 97/274 (35%), Gaps = 20/274 (7%) Query: 1110 SETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEE 1169 S T G++ N S + + + + S S E N E Sbjct: 170 SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE 229 Query: 1170 KRHVDQPIDYSLKYATDIPSSQKQSFSFSKSS---SGQSSKTEHMSS---------SSEN 1217 + + PSS + + S+SS SG + T SS ++ Sbjct: 230 SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSE 289 Query: 1218 TSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFS 1272 +STPSS A S+ S + + + SS N E+ T T S Sbjct: 290 SSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST-ATNS 348 Query: 1273 RCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRT 1332 S+ SS +S G + T+ +A + + + T + + + S + Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408 Query: 1333 KSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGA 1366 +SS + SS +S + ++ SSGA + + SG+ Sbjct: 409 ESSTV--SSGASTATNSESSTTSSGANTATNSGS 440 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 69.7 bits (169), Expect = 4e-11 Identities = 292/1468 (19%), Positives = 485/1468 (33%), Gaps = 224/1468 (15%) Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183 +ED K T S+ S E EEEE + K N D P K Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125 Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243 + + K S ++G++ S ++ PS+N ++ + G Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185 Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303 K + + EDT SS S + E + +A S +T + Sbjct: 186 AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232 Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360 K D +V + P ++ + + S SSE E +G +S Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292 Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398 P K P +T P S +S S DS E Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352 Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432 A ++ SG S + + S P PG+T P Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412 Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485 S + P A+ + P+ +A +A +ES K AA A +VQV Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532 + + ES D +L+A++ + P ++ + + P PV Sbjct: 473 EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528 Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592 G T S Q + E+ E +E++ DS + + E I+ A PT S AK Sbjct: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586 Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651 P Q A + V A KP S + + + T P + + Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646 Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711 T T+ S A VR G Q+ K T + S+ GG P Sbjct: 647 KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689 Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771 D + +EE D E A+ G++ K + +Q +A S P K L G+ Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740 Query: 1772 PTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNE 1831 P P K P T+ + +++++S SD++++ + + V + N Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESSEE------ESDSEEAAASPAQVKTSVKKTQAKANP 794 Query: 1832 DRVRGSFA---FDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888 R A +P S + + + L+R A + + Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854 Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATD 1948 + A+ + E S + + + +P + +K+ P +GAA Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914 Query: 1949 E--KLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSK-PQAS 2005 K A + S +SS S SD + + IK PP +P++ P Sbjct: 915 PPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK---PPLIFVDPNRSPAGP 971 Query: 2006 GYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLL--QECIS-----------SAMPK- 2049 P TP S +++ SS S ++D++ +C++ +A P+ Sbjct: 972 AATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031 Query: 2050 KKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGAN 2109 K S + K S R G E + DS G P + +G N Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQV------DSAVGTLPATSPQSTSVQAKGTN 1085 Query: 2110 SIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILK 2169 + A + ++S DS+ S S GS Q K + GP Sbjct: 1086 KLRKPKLPEVQQATKAPESSDDSED----SSDSSSGSEEDGEGPQGAKSAHTLVGP---T 1138 Query: 2170 PGEKSTL--ETKKIESESKGIKGGKKVYKSLIT-GKVRSNSEISGQMKQPLQANMPSISR 2226 P TL ET SE + + + +T G +NS+ S P + PS+S Sbjct: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS--KATPKLDSSPSVSS 1196 Query: 2227 GRTMIHIP-------------------GVRNSSSSTSPVS----KKG---PPLKTPASKS 2260 P G + ++S T+P KKG P T A +S Sbjct: 1197 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256 Query: 2261 PSE----GQTATTSPRGAKPSVKSELSPVARQ-TSQIGGSSKAPSRSGSRDSTPSRPAQQ 2315 GQ + + SV L+ + Q ++ ++K SR G Q Sbjct: 1257 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1316 Query: 2316 PLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ 2375 P +R +S + + G G + SP ST S G K R + Sbjct: 1317 PAARTPRSKKKKKLGAGEGG----------EASVSPEKTSTTSKGKAK-------RDKAS 1359 Query: 2376 QNLTKQTG---LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432 ++ ++ G L + E KG+ + G+ +N K + + S K + + Sbjct: 1360 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1419 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 ++ + ST E+PS ++K +++A Sbjct: 1420 KKKKAKKASTKDSESPSQKKKKKKKKTA 1447 Score = 55.8 bits (133), Expect = 6e-07 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%) Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936 E RKA+E+ +AK T ++ S +S+ + + A+ + P+ S Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113 Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996 D+P ++ EK + E + NS + N P K EP + Sbjct: 114 GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167 Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054 S+ + G P +F P V + S S + S D+ E S P + K S Sbjct: 168 TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226 Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110 + + K SP G +G D+T +K P ++ P+ E+ ++ +EG+ S Sbjct: 227 SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279 Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170 + A A S+ +S+ + S + G+P KG P Sbjct: 280 -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320 Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230 G+ + S++K GK +SE S + + P+ + + Sbjct: 321 GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359 Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290 + +S TS V P K K + T P AK + Sbjct: 360 LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415 Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 + +AP+++ P R A P +SP + + P Q+ + Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 S +S++ S S GK P M L K G P Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450 + SA G + ++ + + + + S + ++S +L + T P Sbjct: 533 TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592 Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499 + ++ S S E S S+ PA+ T +QA+ + P T+++ Sbjct: 593 GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652 Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538 A G P SP + RPA + + S ES S Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709 Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598 + + ++ + + ++S+P V G++ + + + + K+E ++ S Sbjct: 710 VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768 Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653 S+E S +K+ + + ++ S+ T A K + Q +P+ K Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828 Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709 P+ NP++ R P + P V +V+ A +D+ + + + Sbjct: 829 P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877 Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769 T+ Q+ A E P P +T S+ S SSS+ Sbjct: 878 EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937 Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821 S G A VT +P+ + +T A+ TP + +++ Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997 Query: 2822 STES 2825 S+ES Sbjct: 998 SSES 1001 Score = 37.4 bits (85), Expect = 0.21 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%) Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591 PI+ S + + E + + +T R ++SS+L A SS EKAK+E EK Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138 Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631 N +SG K + SA T E E S S Q S Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198 Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689 S + S + P+V ++ + V ++ P G+ P + + Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258 Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738 K ++ G+ S G +++ + +QV A P + T Sbjct: 259 PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318 Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783 PG+ V S+T E + SS SS K S + V A P Sbjct: 319 PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377 Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829 SPRK +A + + ++ DS++ S ES + Sbjct: 378 AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421 >gi|28559039 mediator complex subunit 1 [Homo sapiens] Length = 1581 Score = 68.6 bits (166), Expect = 9e-11 Identities = 128/620 (20%), Positives = 218/620 (35%), Gaps = 112/620 (18%) Query: 2227 GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVA 2286 G+ + + + S S P+ G K K EG + S P + S+ + Sbjct: 938 GKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSG-PGLDSKPGKRS 996 Query: 2287 RQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRN--SISPGRNGIS--PPNKL 2342 R S G S P + D+ P+ +RP P S SPG G S PP Sbjct: 997 RTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVA 1056 Query: 2343 SQ-LPRTSSPSTASTKSSG--SGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASK 2399 + +P+ + T G S YTS G S + + + S ++SS S S Sbjct: 1057 TPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA----STSG 1112 Query: 2400 GLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEES 2459 + + ++ K+ S SS SSGS ++ + K SP + L Sbjct: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS------SQSGGKPGSSPITKHGLSSG 1166 Query: 2460 ASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYND 2519 +S + P +P+S +++PSL ++S S GG KL + P Sbjct: 1167 SSSTKMKPQGKPSS---------LMNPSLSKPNISPSHSRPPGGSDKLASPMKPV----P 1213 Query: 2520 GRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSE 2579 G P S ++ PI+ +GS S +S +S Sbjct: 1214 GTPPS----------SKAKSPIS------------------------SGSGGSHMSGTSS 1239 Query: 2580 SSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAE 2639 SS S S+S + +P +S S T SS + + + Sbjct: 1240 SSGMKSSSGLGSSGSLS----------------------QKTPPSSNSCTASSSSFSSSG 1277 Query: 2640 SKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK-------ANP 2692 S Q SK G+SP+ N P + +V +K + P Sbjct: 1278 SSMSSSQNQHGSSK------------------GKSPSRNKKPSLTAVIDKLKHGVVTSGP 1319 Query: 2693 NIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETN 2752 +D D Q + + S PM + + + + D+ +++ ++ +T+ Sbjct: 1320 GGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTS 1379 Query: 2753 ESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNN 2812 ES V T + SKH S ++ A+VT S + ++ + ++ + Sbjct: 1380 ESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGS 1439 Query: 2813 TKKRDSKTDSTESSGTQSPK 2832 T K + + S S +P+ Sbjct: 1440 TPKHERGSPSHSKSPAYTPQ 1459 Score = 56.6 bits (135), Expect = 3e-07 Identities = 141/651 (21%), Positives = 228/651 (35%), Gaps = 116/651 (17%) Query: 2187 GIKGGKKVYKSLITGKVRSNSEISG---QMKQPLQANMPSISRGRTMIHIPGVRNS---- 2239 G G +K K + G SNS +SG K ++ PS + G++ P + + Sbjct: 961 GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPS-NDGKSKDKPPKRKKADTEG 1019 Query: 2240 -----SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIG- 2293 SSS P + PP T SKSP + T P A P + + + T +G Sbjct: 1020 KSPSHSSSNRPFT---PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGK 1076 Query: 2294 -------GSSKAPSRSGSR------DSTPSRPAQQPLSRPIQSPGRNS--------ISPG 2332 SS + S SGS+ S+ S + + +S G +S S G Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136 Query: 2333 RNGISPPNKLSQL--PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQN--LTKQT------ 2382 +G S SQ SSP T SSGS G+ S N L+K Sbjct: 1137 SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196 Query: 2383 ----GLSKNAS---SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERP 2435 G K AS +P + +SK + +++G+G + S S KSS Sbjct: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256 Query: 2436 VLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLST 2495 S+ A S + +S ++ SS+ SP+R+ + P L+ + + Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN--KKPSLTAVIDKLK--- 1311 Query: 2496 HSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHS 2555 H V +G + P + + N + H ++ H+ S G ++ + K Sbjct: 1312 HGVVTSGPGGEDPLDGQMGVSTN----SSSHPMSSKHNMS--------GGEFQGKREKSD 1359 Query: 2556 SSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKI 2615 +VST S S + +S ++SE I + AK T +K Sbjct: 1360 KDKSKVST------SGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKP 1413 Query: 2616 KENE---FSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672 E+ P ++S+ S +G+ K +P Sbjct: 1414 GESSGEGLRPQMASSKNYGSPLISGSTPKH----------------------ERGSPSHS 1451 Query: 2673 RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR----------- 2721 +SP TP +DS SE + + S N + G +P + + Sbjct: 1452 KSP-AYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDK 1510 Query: 2722 -LNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS 2771 + D +K IKP + P+S S+ T S+ S+ S Sbjct: 1511 DRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLS 1561 Score = 47.0 bits (110), Expect = 3e-04 Identities = 61/219 (27%), Positives = 90/219 (41%), Gaps = 14/219 (6%) Query: 1188 PSSQKQ-SFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKA 1246 PSS Q + S S SSSG S H SSSS + ST S + ++ SS+ S + Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST--SGKMKSSKSEGSSSSKLSSSMYSS 1134 Query: 1247 ATCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIA 1305 SS ++ + Q+ +PI SS SS + + + + + S + + Sbjct: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS 1194 Query: 1306 EIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSG 1365 + G+ P+ VP + KS GS S S SSG KS S G Sbjct: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS----GTSSSSGMKSSSGLG 1250 Query: 1366 AQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404 + S Q+TP + CT+ SS S S++SS Sbjct: 1251 SSGSLS------QKTPPSSNSCTASSSSFSSSGSSMSSS 1283 Score = 39.3 bits (90), Expect = 0.056 Identities = 117/590 (19%), Positives = 200/590 (33%), Gaps = 90/590 (15%) Query: 2298 APSRSGSRDSTPSRPAQQP---LSRPIQSPGRNSISPGRNGISPP--NKLSQLPRTSSP- 2351 APS+ + +T +P P + R ++ +SI P I + S+LP TS Sbjct: 741 APSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDC 800 Query: 2352 ---STASTKSSGSGKMSYTSPGRQMSQQN-----LTKQTGLSKNASSIPRSESASKGLNQ 2403 T SS SG T + Q N T L +A+ P S+S + Sbjct: 801 PAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFH 860 Query: 2404 MNNGNGANKKVELSRMSSTKSSGSE--------SDRSERPVLVRQSTFIKEAP------- 2448 +G + +L S G E D + Q+ P Sbjct: 861 ----DGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNG 916 Query: 2449 -SPTLRRKLEESASFESLSPSSRPASPT-----RSQAQTPVLSPSLPDMSLS-THSSVQA 2501 + ++ F +S + + +P S +Q P+L+ D+ T V+ Sbjct: 917 ETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTG--DLGKEKTQKRVKE 974 Query: 2502 GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRV 2561 G P + D +P KR + +S + P + + + HSSS Sbjct: 975 GNGTSNSTLSGPGL---DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPF 1031 Query: 2562 STWRRTGSSSSILSASSESSEKA-------KSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614 + TG S S SA + K + ++ K S +Q ++ G+ Sbjct: 1032 TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSS 1091 Query: 2615 I-------KENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPIN 2667 + S + STS + S + G+ S L M + + + N Sbjct: 1092 SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK------N 1145 Query: 2668 NPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQ 2727 + +SG P G++P +S G+ S M+ G + L + Sbjct: 1146 SSQSGGKP-GSSPITKHGLSS------------------GSSSTKMKPQGKPSSLMN--- 1183 Query: 2728 VDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYN 2787 P I P + P S+ S + SS +K SG+ + ++ + + Sbjct: 1184 ---PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSS 1240 Query: 2788 PSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 + SS +S SQ P +N+ S S+ SS + S +H S Sbjct: 1241 SGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290 Score = 33.1 bits (74), Expect = 4.0 Identities = 92/398 (23%), Positives = 138/398 (34%), Gaps = 75/398 (18%) Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-----QNQLHPSSAQSRSGQ 1242 PS K + S S S S + PSS AK H S S SG Sbjct: 1184 PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGM 1243 Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQ---TTQEADSA 1299 + S++Q+T + T S SS SS+SS++++ G ++ ++ + Sbjct: 1244 KSSSGLGSSGSLSQKTPPS-SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPS 1302 Query: 1300 NTLQIAEIKEKIGTRS--AEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSG 1357 T I ++K + T EDP+ VS + SS S++H S G Sbjct: 1303 LTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN----------SSSHPMSSKHN---MSGG 1349 Query: 1358 AKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGI 1417 + + KS TS SS+DS + S + +V S +G+ I Sbjct: 1350 EFQGKREKSDKDKSKVS-------------TSGSSVDSSKKTSESKNVGS---TGVAKII 1393 Query: 1418 ISPSDLPDSPG-----QTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAV 1472 IS D SP P S PQ A +K + + K E G + Sbjct: 1394 ISKHD-GGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSK 1452 Query: 1473 NAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND 1532 + A TP S S S S+ E Q +D Sbjct: 1453 SPAY-------------------TPQNLD-SESESGSSIAEKSYQNS---------PSSD 1483 Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDD 1570 +G E E ++ +KE +K D ++D D D D Sbjct: 1484 DGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRD 1521 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 67.4 bits (163), Expect = 2e-10 Identities = 178/848 (20%), Positives = 300/848 (35%), Gaps = 135/848 (15%) Query: 1753 ASASSSAPNKNQLDG-KKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDS 1811 AS + SAP + P P+ PI N + R + ++ + N + + K Sbjct: 187 ASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSP 246 Query: 1812 KKQNLKNNSKVF-NDKLPNNEDRVRGSFAFDS-----------PHHYT-PIEGTPYCFSR 1858 K +K + K D L +F S P Y P++G S Sbjct: 247 KDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSE 306 Query: 1859 NDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPI 1918 + L L +D + EK +L+ + K ++ K+ S + + + + I K+ Sbjct: 307 SPELKPLP--EDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMT 364 Query: 1919 NRGQPK------PILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSL 1972 + P P + S FP +KD + T + Q T H++S Sbjct: 365 HSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKT-----HSNSQQGT 419 Query: 1973 SDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSI 2032 S + +++ + ++E DS+ P KP +S P + PV + +SS S S Sbjct: 420 SSMLEDDLQ-----LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESEST 474 Query: 2033 -DSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHG 2091 DS+ E SS+ ++ E P L LT + P+ Sbjct: 475 SDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRS 534 Query: 2092 LSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLT 2151 P + + K + A S Q S+S Sbjct: 535 TEPPRRHPESKGSSDSATS----------------QEHSES------------------- 559 Query: 2152 PDQEEKPFTSNKGPR----ILKPG----EKSTLETKKIESESKGIKGGKKVYKSLITGKV 2203 ++ P +S+K PR PG +KS + + + ++ G K KK K+ + + Sbjct: 560 --KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKA--SARA 615 Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSE 2263 S + + G+ + L +P SR +T P V+ + S + P P+S+ Sbjct: 616 GSRTSLQGEREPGL---LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKH 672 Query: 2264 GQT------ATTSPRGAKPSVK----SELSPVARQTSQIGGSSKAPSR-SGSRDSTPSRP 2312 + A + P AK +V+ + V SQ S + SR SG R + + Sbjct: 673 KSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQE 732 Query: 2313 AQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372 + P+ +SP R+ +PP + + T + + G G RQ Sbjct: 733 DSRKDRLPLPLRDTKLLSPLRD--TPPPQSLMVKITLDLLSRIPQPPGKG-------SRQ 783 Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGA----NKKVELSRMSSTKSSGSE 2428 ++ KQ K SS RS +S L + G NKK+ L + ++SS S Sbjct: 784 RKAED--KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSS 841 Query: 2429 SDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSP------SSRPASPT--RSQAQ 2480 S E K PS R +S+ E L P S +PA P RS+ + Sbjct: 842 SSHKESS---------KTKPS----RPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRRE 888 Query: 2481 TPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLP 2540 P + ST S+ + K +E R + H + + +P +P Sbjct: 889 ADTCGQDPPKSASSTKSNHKDSSIPK-----QRRVEGKGSRSSSEHKGSSGDTANPFPVP 943 Query: 2541 INRSGTWK 2548 +G K Sbjct: 944 SLPNGNSK 951 Score = 51.6 bits (122), Expect = 1e-05 Identities = 112/524 (21%), Positives = 194/524 (37%), Gaps = 80/524 (15%) Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAA 1247 P S + + + SSS +S T SSS++ S SS+ +N+ P + +P Sbjct: 454 PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE--PLETPAPEPEPPTTN 511 Query: 1248 TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEI 1307 ++ + + Q + P S E ++ +DSA + + +E Sbjct: 512 KWQLDNWLTKVSQPAAPPEGP------------RSTEPPRRHPESKGSSDSATSQEHSES 559 Query: 1308 KEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQ 1367 K+ S++ P P + HP +S Q S E + + V + K P K+ A+ Sbjct: 560 KDPPPKSSSKAP--RAPPEAPHPGKRS--CQKSPAQQEPPQRQTVG-TKQPKKPVKASAR 614 Query: 1368 TPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS-----IASSVQSEPCSGMVSGIISPSD 1422 +E L+ +S D + ++ A+S + +P + PS Sbjct: 615 AGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPA-------VPPSS 667 Query: 1423 LPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA--PTAE----------KRESGPKQA 1470 ++P P P + P++ A P E R SG +QA Sbjct: 668 EKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQA 727 Query: 1471 AVNAAVQRVQVLP----DADTLLHFATESTPDGFSCSSSLSALS-LDEP----FIQKDVE 1521 V R LP D L P +L LS + +P Q+ E Sbjct: 728 VVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAE 787 Query: 1522 LRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIIS 1581 + PP + + + S+ + + ++ EAE+ D++K L+ EI + S Sbjct: 788 DK-QPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEK------EIKSQSSSS 840 Query: 1582 AMPTKSSRKAK--KPAQTASK---LPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGD 1636 + K S K K +P+ +SK LPPP SQ P++ L+ + + T G Sbjct: 841 SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQ------KPAKPALKRSRREADTCGQ 894 Query: 1637 DMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680 D P+ ST ++ D +I P G+G R ++ Sbjct: 895 DPPKSAS--------STKSNHKDSSI--PKQRRVEGKGSRSSSE 928 Score = 51.2 bits (121), Expect = 1e-05 Identities = 143/731 (19%), Positives = 253/731 (34%), Gaps = 143/731 (19%) Query: 1922 QPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNN 1981 +P P +Q TF ++ +P + T K+ + ++E T +++ + + +I +E + Sbjct: 311 KPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQT-----YSNEVHCVEEILKEMTH 365 Query: 1982 KENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE 2041 P+ P S EPSK S HV Sbjct: 366 SWPPPLTAIHTP-STAEPSKFPFP--TKDSQHV--------------------------- 395 Query: 2042 CISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDW 2101 S++ + +K +S + +L +DL L D + DSE + Sbjct: 396 ---SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL--QLSDSEDSDSEQTPEKPPSSSAP 450 Query: 2102 KAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTS 2161 + + V+S H ++A + + + S SDS S S + TP E +P T+ Sbjct: 451 PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTT 510 Query: 2162 NKG-----------PRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEIS 2210 NK P G +ST E + ESKG + S+ Sbjct: 511 NKWQLDNWLTKVSQPAAPPEGPRST-EPPRRHPESKGSSDS-------------ATSQEH 556 Query: 2211 GQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTS 2270 + K P + R PG R S SP ++ P +T +K P + A+ Sbjct: 557 SESKDPPPKSSSKAPRAPPEAPHPGKR--SCQKSPAQQEPPQRQTVGTKQPKKPVKASAR 614 Query: 2271 PRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSI 2329 G++ S++ E P GSRD T +P + RP ++ N Sbjct: 615 A-GSRTSLQGEREPGLLPY-------------GSRDQTSKDKPKVKTKGRP-RAAASNEP 659 Query: 2330 SPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNAS 2389 P PP+ + ++S P+ + S G + ++ N+ +T ++ + Sbjct: 660 KPA----VPPSSEKKKHKSSLPAPSKALS-----------GPEPAKDNVEDRT--PEHFA 702 Query: 2390 SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449 +P +ES SGS + + V+V++ + P Sbjct: 703 LVPLTESQGP---------------------PHSGSGSRTSGCRQAVVVQEDSRKDRLPL 741 Query: 2450 PTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP 2509 P KL LSP P Q+ ++ +L +S + RK Sbjct: 742 PLRDTKL--------LSPLRDTPPP-----QSLMVKITLDLLSRIPQPPGKGSRQRKAED 788 Query: 2510 NLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS 2569 P K+H + S+S S+L R G +R+ L + + + S Sbjct: 789 KQPPA--------GKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS 840 Query: 2570 SSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQT 2629 SSS +S + S+ K + S +Q AK ++ + + ++ Sbjct: 841 SSSHKESSKTKPSRPSSQSSKK-EMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKS 899 Query: 2630 VSSGATNGAES 2640 SS +N +S Sbjct: 900 ASSTKSNHKDS 910 Score = 42.0 bits (97), Expect = 0.009 Identities = 63/282 (22%), Positives = 98/282 (34%), Gaps = 25/282 (8%) Query: 1152 QHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIP---SSQKQSFSFSKSSSGQSSKT 1208 Q + E++ K++ EKR D + K + ++K S SS + Sbjct: 783 QRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS 842 Query: 1209 EHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTP 1268 H SS S PSS + ++ L P S S +P K A K S +T C +D P Sbjct: 843 SHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPA-LKRSRREADT----CGQDPP 897 Query: 1269 ICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQ 1328 S S SS + + + + +E K G + PV +P + Sbjct: 898 KSASSTKSNHKDSSIPKQ-------RRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNS 950 Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCT 1388 P G + + K K+ T + E L F C Sbjct: 951 KP--------GKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECG 1002 Query: 1389 SVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQT 1430 + +S S+S A SV SE ++ I+S D+ T Sbjct: 1003 IATESESQSSKS-AYSVYSETVD-LIKFIMSLKSFSDATAPT 1042 Score = 32.3 bits (72), Expect = 6.9 Identities = 87/391 (22%), Positives = 132/391 (33%), Gaps = 52/391 (13%) Query: 1320 VSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQE 1379 VS V + T S S + S ++ S S S+ QTP+ PP Sbjct: 395 VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSE---QTPEKPPSSSAPP 451 Query: 1380 TPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTP 1439 + + SL + + +SS +SE S S S S+ S + P + P Sbjct: 452 S--------APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503 Query: 1440 PPPPQTA---QTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496 P P T Q + K P A GP+ + D+ T + Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAP--PEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561 Query: 1497 PDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT 1556 P S SS + P K + P QE ++QPK+ + + +T Sbjct: 562 PPPKS-SSKAPRAPPEAPHPGKR-SCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRT 619 Query: 1557 I---DSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK---KPAQTASKLPPPVARKPS 1610 + E LL D +K K K +P AS P P S Sbjct: 620 SLQGEREPGLLPYGSRD------------QTSKDKPKVKTKGRPRAAASNEPKPAVPPSS 667 Query: 1611 QLPVYK-LLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNEL 1669 + +K LP+ P K +S G + + + TP +F +L LT P Sbjct: 668 EKKKHKSSLPA-----PSKALS---GPEPAKDNVEDRTPEHF----ALVPLTESQGPPHS 715 Query: 1670 AAGEGVRGGAQS---GEFEKRDTIPTEGRST 1697 +G G Q+ E ++D +P R T Sbjct: 716 GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDT 746 >gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo sapiens] Length = 1450 Score = 67.0 bits (162), Expect = 3e-10 Identities = 292/1468 (19%), Positives = 484/1468 (32%), Gaps = 225/1468 (15%) Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183 +ED K T S+ S E EEEE + K N D P K Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125 Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243 + + K S ++G++ S ++ PS+N ++ + G Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185 Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303 K + + EDT SS S + E + +A S +T + Sbjct: 186 AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232 Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360 K D +V + P ++ + + S SSE E +G +S Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292 Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398 P K P +T P S +S S DS E Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352 Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432 A ++ SG S + + S P PG+T P Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412 Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485 S + P A+ + P+ +A +A +ES K AA A +VQV Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532 + + ES D +L+A++ + P ++ + + P PV Sbjct: 473 EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528 Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592 G T S Q + E+ E +E++ DS + + E I+ A PT S AK Sbjct: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586 Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651 P Q A + V A KP S + + + T P + + Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646 Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711 T T+ S A VR G Q+ K T + S+ GG P Sbjct: 647 KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689 Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771 D + +EE D E A+ G++ K + +Q +A S P K L G+ Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740 Query: 1772 PTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNE 1831 P P K P T+ + +++++S SD++++ + + V + N Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSESSEE------ESDSEEAAASPAQVKTSVKKTQAKANP 794 Query: 1832 DRVRGSFA---FDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888 R A +P S + + + L+R A + + Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854 Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATD 1948 + A+ + E S + + + +P + +K+ P +GAA Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914 Query: 1949 E--KLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSK-PQAS 2005 K A + S +SS S SD + + IK PP +P++ P Sbjct: 915 PPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK---PPLIFVDPNRSPAGP 971 Query: 2006 GYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLL--QECIS-----------SAMPK- 2049 P TP S +++ SS S ++D++ +C++ +A P+ Sbjct: 972 AATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031 Query: 2050 KKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGAN 2109 K S + K S R G E + DS G P + +G N Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQV------DSAVGTLPATSPQSTSVQAKGTN 1085 Query: 2110 SIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILK 2169 + A + ++S DS+ S S GS Q K GP Sbjct: 1086 KLRKPKLPEVQQATKAPESSDDSED----SSDSSSGSEEDGEGPQGAKS-AHTLGP---T 1137 Query: 2170 PGEKSTL--ETKKIESESKGIKGGKKVYKSLIT-GKVRSNSEISGQMKQPLQANMPSISR 2226 P TL ET SE + + + +T G +NS+ S P + PS+S Sbjct: 1138 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS--KATPKLDSSPSVSS 1195 Query: 2227 GRTMIHIP-------------------GVRNSSSSTSPVS----KKG---PPLKTPASKS 2260 P G + ++S T+P KKG P T A +S Sbjct: 1196 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1255 Query: 2261 PSE----GQTATTSPRGAKPSVKSELSPVARQ-TSQIGGSSKAPSRSGSRDSTPSRPAQQ 2315 GQ + + SV L+ + Q ++ ++K SR G Q Sbjct: 1256 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1315 Query: 2316 PLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ 2375 P +R +S + + G G + SP ST S G K R + Sbjct: 1316 PAARTPRSKKKKKLGAGEGG----------EASVSPEKTSTTSKGKAK-------RDKAS 1358 Query: 2376 QNLTKQTG---LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432 ++ ++ G L + E KG+ + G+ +N K + + S K + + Sbjct: 1359 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1418 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 ++ + ST E+PS ++K +++A Sbjct: 1419 KKKKAKKASTKDSESPSQKKKKKKKKTA 1446 Score = 55.8 bits (133), Expect = 6e-07 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%) Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936 E RKA+E+ +AK T ++ S +S+ + + A+ + P+ S Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113 Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996 D+P ++ EK + E + NS + N P K EP + Sbjct: 114 GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167 Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054 S+ + G P +F P V + S S + S D+ E S P + K S Sbjct: 168 TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226 Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110 + + K SP G +G D+T +K P ++ P+ E+ ++ +EG+ S Sbjct: 227 SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279 Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170 + A A S+ +S+ + S + G+P KG P Sbjct: 280 -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320 Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230 G+ + S++K GK +SE S + + P+ + + Sbjct: 321 GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359 Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290 + +S TS V P K K + T P AK + Sbjct: 360 LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415 Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 + +AP+++ P R A P +SP + + P Q+ + Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 S +S++ S S GK P M L K G P Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450 + SA G + ++ + + + + S + ++S +L + T P Sbjct: 533 TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592 Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499 + ++ S S E S S+ PA+ T +QA+ + P T+++ Sbjct: 593 GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652 Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538 A G P SP + RPA + + S ES S Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709 Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598 + + ++ + + ++S+P V G++ + + + + K+E ++ S Sbjct: 710 VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768 Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653 S+E S +K+ + + ++ S+ T A K + Q +P+ K Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828 Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709 P+ NP++ R P + P V +V+ A +D+ + + + Sbjct: 829 P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877 Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769 T+ Q+ A E P P +T S+ S SSS+ Sbjct: 878 EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937 Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821 S G A VT +P+ + +T A+ TP + +++ Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997 Query: 2822 STES 2825 S+ES Sbjct: 998 SSES 1001 Score = 37.4 bits (85), Expect = 0.21 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%) Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591 PI+ S + + E + + +T R ++SS+L A SS EKAK+E EK Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138 Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631 N +SG K + SA T E E S S Q S Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198 Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689 S + S + P+V ++ + V ++ P G+ P + + Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258 Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738 K ++ G+ S G +++ + +QV A P + T Sbjct: 259 PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318 Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783 PG+ V S+T E + SS SS K S + V A P Sbjct: 319 PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377 Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829 SPRK +A + + ++ DS++ S ES + Sbjct: 378 AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 65.9 bits (159), Expect = 6e-10 Identities = 161/764 (21%), Positives = 274/764 (35%), Gaps = 88/764 (11%) Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182 S+++++ S S + +S GS L+ QE F SN G ST + +E Sbjct: 1047 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 1106 Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224 S S G++G +++ + S S ++ Sbjct: 1107 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 1166 Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 S G T H P +SS+TS S+K + S + +A ++ G S S +S Sbjct: 1167 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ-----QPLSRPIQSPGRNSIS----PGRN 2334 P + + + + GS+ P S + + S P P S G S + PG Sbjct: 1223 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 1282 Query: 2335 GISPPNKLSQLPRTSSPSTASTKSS-GSGKMSYTSPGRQMSQQNLTKQTGLSKNAS---S 2390 + + P S ST SS GS + + S T S+ AS + Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342 Query: 2391 IPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEA 2447 + +S + GL + + G+ A+ + L +T G ES ST K + Sbjct: 1343 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTKLS 1399 Query: 2448 PSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTHSS 2498 P+ + L ++ LSPSS P SPT ++ T SP PD +LS ++ Sbjct: 1400 PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 1459 Query: 2499 VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL 2558 +G +S + +P H A S + S L + + + S ++ Sbjct: 1460 TSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511 Query: 2559 PRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKEN 2618 P +T G S+ +S +E D+ SG ++ S+ G+ Sbjct: 1512 PGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH----- 1563 Query: 2619 EFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGN 2678 T+ T +S + G + ++ +Q P+ S T P+ + S + Sbjct: 1564 -------TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616 Query: 2679 TPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE 2737 TP S S ++S + + G P R+ + + V P Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSPIS 1669 Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKSSA 2795 + +P S T + T F SS S + SP+ T ++ V+ + R S Sbjct: 1670 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1729 Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839 +T+ S V+ + S ST++ T SP + S L Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 1771 Score = 65.5 bits (158), Expect = 7e-10 Identities = 153/766 (19%), Positives = 278/766 (36%), Gaps = 92/766 (12%) Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182 S+++++ S S + +S GS L+ QE F S+ G ST + +E Sbjct: 3687 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 3746 Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224 S S G++G +++ + S S ++ Sbjct: 3747 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 3806 Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 S G T H P +SS+TS S+K + S + +A ++ G S S +S Sbjct: 3807 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 3862 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343 P + + + + GS+ P S + + S P + + S+ G + ++ Sbjct: 3863 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSP--TTTLSPASMTSLGVGEESTTSRSQPG 3920 Query: 2344 QLPRTSSPSTASTK--SSGSGKMSYTSPGRQMS-------------QQNLTKQTGLSKNA 2388 T SP++ +T S S + +SPG + ++ T + + Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980 Query: 2389 SSIPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445 +++ +S + GL + + G+ A+ + L +T G ES ST K Sbjct: 3981 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTK 4037 Query: 2446 EAPSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTH 2496 +P+ + L ++ LSPSS P SPT ++ T SP PD +LS Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097 Query: 2497 SSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSS 2556 ++ +G +S + +P H A S + S L + + + S ++ Sbjct: 4098 TTTSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 4149 Query: 2557 SLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIK 2616 P +T G S+ +S +E D+ SG ++ S+ G+ Sbjct: 4150 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH--- 4203 Query: 2617 ENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPT 2676 T+ T +S + G + ++ +Q P+ S T P+ + S Sbjct: 4204 ---------TTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRP 4254 Query: 2677 GNTPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKG 2735 +TP S S ++S + + G P R+ + + V P Sbjct: 4255 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSP 4307 Query: 2736 TEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKS 2793 + +P S T + T F SS S + SP+ T ++ V+ + R Sbjct: 4308 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367 Query: 2794 SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839 S +T+ S V+ + S ST++ T SP + S L Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 4411 Score = 64.3 bits (155), Expect = 2e-09 Identities = 138/656 (21%), Positives = 249/656 (37%), Gaps = 75/656 (11%) Query: 2216 PLQANMPSISRGRTMIH-IPGVRNSSSS--TSPVSKKGPPLKTPASKSPSEGQTATTS-P 2271 P MP +S+ T H IPG +++ S T+ S GP T S S G T TT P Sbjct: 324 PDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHS---SPGYTKTTRLP 380 Query: 2272 RGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP 2331 S E S ++ ++ +PS S + + P+ P S+ SP Sbjct: 381 DNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSK--------DTSP 432 Query: 2332 GRNGISPPN-KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASS 2390 +G + KLS +S ST +T S S T+ G S+++ + A++ Sbjct: 433 APSGTTSAFVKLSTTYHSSPSSTPTTHFSASS----TTLGH--SEESTPVHSSPVATATT 486 Query: 2391 IPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP 2450 P + SA+ G + ++ ++ S + S SE ST ++ +P Sbjct: 487 PPPARSATSG--HVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP 544 Query: 2451 TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510 + L ++ SL + T + + + S + S ++HSS A LP Sbjct: 545 STTAALAHTSYHSSLGSTET----THFRDSSTISGRS--EESKASHSSPDAMATTVLPAG 598 Query: 2511 LSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSS 2570 +P++ D P+ S S + LP + + E S S PR +S Sbjct: 599 STPSVLVGDSTPSP----ISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPAS 654 Query: 2571 SSILSASSESSEKAKSEDEKHVNSISG--TKQSKENQVSAKGTWRKIKENEFSPTNSTSQ 2628 + S ES+ H + G T + +A + + SP ++T+ Sbjct: 655 MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 714 Query: 2629 TVSSGATN-----GAESKTLIYQMAPAVSKTEDVWVRIEDCPIN----NPRSGRSPTGNT 2679 ++ T G+ TL+ A E P++ +P + SP G+T Sbjct: 715 SLGPEYTTFHSRPGSTETTLLPDNTTASGLLE------ASMPVHSSTRSPHTTLSPAGST 768 Query: 2680 PPVIDSVSEKANPNIKDSK-----------DNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728 +S + + P+ KD++ + + S+P + + + ++ Sbjct: 769 TRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVE- 827 Query: 2729 DAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKH---SSPSGTVAARVTPFN 2785 + PG + E++ +S +S SS+ H S+PS T A P + Sbjct: 828 ---ESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 884 Query: 2786 YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGT-QSPKRHSGSYLV 2840 Y+ SP + +T+ P T + +++ + S +++GT P R + S L+ Sbjct: 885 YHSSP---GSTATTHFPDSSTT--SGRSEESTASHSSQDATGTIVLPARSTTSVLL 935 Score = 61.2 bits (147), Expect = 1e-08 Identities = 146/654 (22%), Positives = 246/654 (37%), Gaps = 93/654 (14%) Query: 2234 PGVRNSSSSTSPVSKKGPPLKTPASKSPSE-GQTATT-SPRGAKPS------VKSELSPV 2285 PG S+ + P + L ++ PS G T TT SP + S S LSP Sbjct: 2918 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2977 Query: 2286 ARQTSQIGGSSKAPSRS----------GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNG 2335 + +T+ + GS PS S S D+T S PA S + + PG Sbjct: 2978 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTH 3036 Query: 2336 ISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPG----RQMSQQNLTKQTGLSKNASSI 2391 + + S TAS S GS + + SPG + QQ+ T + +++ Sbjct: 3037 TTAFPDSTTTSGLSQEPTASHSSQGSTEAT-LSPGSTTASSLGQQSTTFHSSPGDTETTL 3095 Query: 2392 PRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP- 2450 ++ + GL + + ++ L + SS S + E + PSP Sbjct: 3096 LPDDTITSGLVEASTPTHSSTG-SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP 3154 Query: 2451 -TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP 2509 T +E S ++ S PSS P T A + L S + S + HSS A G P Sbjct: 3155 GTTAAPVEVSTTYHS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPT 3209 Query: 2510 NLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS 2569 + ++ G P S S + LP + + E S S PR + + Sbjct: 3210 RSATSVLV--GEPTT--SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA 3265 Query: 2570 SSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQT 2629 S++ S ES+ H + G+ + G ++ + SP ST T Sbjct: 3266 STTSSGVSEESTTSHSRPGSTHTTAFPGS-------TTMPGVSQESTASHSSP-GSTDTT 3317 Query: 2630 VSSGATN----GAESKTLIYQMAPAVSKTEDV-------WVRIEDCPIN----NPRSGRS 2674 +S G+T G ES T + P ++T + + P++ +P + S Sbjct: 3318 LSPGSTTASSLGPESTT--FHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 3375 Query: 2675 PTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQK 2734 P G+T +S + ++ PN KD+ T ++F+++ Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDT-----------------TPAPPTTTSAFVELSTTSHG 3418 Query: 2735 GTEIKPGQN---NPVPVSETNESSIVERTPFSSSS--SSKHSSPSGTVAARVTPFNYNPS 2789 P + + + + ES+ V +P ++++ S S+ SG V T Y+ S Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTT---YHSS 3475 Query: 2790 PRKS------SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 P + +D+TS R + T +++T S ST S+ + P + S Sbjct: 3476 PGSTQTMHFPESDTTSGRGEE-STTSHSSTTHTISSAPSTTSALVEEPTSYHSS 3528 Score = 59.3 bits (142), Expect = 5e-08 Identities = 163/829 (19%), Positives = 283/829 (34%), Gaps = 154/829 (18%) Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182 S+++++ S S + +S GS L+ QE F S+ G ST + +E Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2189 Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224 S S G++G +++ + S S ++ Sbjct: 2190 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 2249 Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 S G T H P +SS+TS S+K + S + +A ++ G S S +S Sbjct: 2250 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 2305 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343 P + + + + GS+ P S + + S P + + S+ G + ++ Sbjct: 2306 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSP--TTTLSPASMTSLGVGEESTTSRSQPG 2363 Query: 2344 QLPRTSSPSTASTK--SSGSGKMSYTSPGRQ-------------MSQQNLTKQTGLSKNA 2388 T SP++ +T S S + +SPG ++ T + + Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTH 2423 Query: 2389 SSIPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESD--------------- 2430 +++ +S + GL + + G+ A+ + L +T G ES Sbjct: 2424 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483 Query: 2431 -RSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS-----RPASPTRSQAQTPVL 2484 RS LV +ST + +PS T L S + SLS S P SP + + Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT 2543 Query: 2485 SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG--RPAKRHDIARSHSESPSR---- 2538 S + + S ++HS P + T + D P SHS S Sbjct: 2544 SSGVSEESSTSHSQ----------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593 Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHV------ 2592 LP + + + + S S S P + + S++ LS ES+ S H Sbjct: 2594 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS 2653 Query: 2593 NSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVS 2652 + SG ++ S+ G+ R SP +STS G + ++ +Q PA + Sbjct: 2654 TTSSGIVEASTRVHSSTGSPR----TTLSPASSTSP--------GLQGESTTFQTHPAST 2701 Query: 2653 KTEDVWVRIEDCPINNPRSGRSPTGNTP-----------------------PVIDSVSEK 2689 T P+ + G+TP P + Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761 Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTV-------GLENRLNSFIQVDAPDQKGTEIKPGQ 2742 + + + + GS + T+ GL +F +P T + P Sbjct: 2762 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF--YSSPRSPTTTLSPAS 2819 Query: 2743 NNPVPVSETNESSIVE-------------RTP-FSSSSSSKHSSPSGTVAARVTPFNYNP 2788 + V E + +S + TP S S++ +SS G+ V P + Sbjct: 2820 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 2879 Query: 2789 SPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 S R + +RP+ T + DST S T+ GS Sbjct: 2880 SVRGEEPTTFHSRPASTHTTLFTE--------DSTTSGLTEESTAFPGS 2920 Score = 57.4 bits (137), Expect = 2e-07 Identities = 135/647 (20%), Positives = 228/647 (35%), Gaps = 80/647 (12%) Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281 IS G T +PG S++T+ +S+K +P S + +TTS ++ S S Sbjct: 1668 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1723 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339 P + T+ GS+ P S ++ S P + S +S+ P SP Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1783 Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395 + + L ++ ++ ++S S SP +S T + G S S P S+ Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1843 Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432 SA L+ ++G+ ++ SST SE RS Sbjct: 1844 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1903 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490 LV +ST +P T ES++ S SR +S T + + P + +L + Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1963 Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKRE 2550 S HSS P + T + D RS + S + +GT Sbjct: 1964 EPTSYHSS----------PGSTATTHFPDSSTTS----GRSEESTASHSSQDATGTIVLP 2009 Query: 2551 HSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKG 2610 +S L ST +S I S S E++ S ++ S T S + Sbjct: 2010 ARSTTSVLLGEST------TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPA--- 2060 Query: 2611 TWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR 2670 SP ++TS VS +T + A S T R ++ Sbjct: 2061 -------TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSR------HSTT 2107 Query: 2671 SGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDA 2730 S SP ++ + + + P+ + + + + + P T L S + Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167 Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSP 2790 P T + P + E + + + T ++ S SS S + T F +P Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEAS-TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP-- 2224 Query: 2791 RKSSADSTSARPSQIPTPVNNNT--KKRDSKTDSTESSGTQSPKRHS 2835 +S +T + PS PV +T + T +T + + HS Sbjct: 2225 --ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 2269 Score = 57.0 bits (136), Expect = 3e-07 Identities = 129/621 (20%), Positives = 226/621 (36%), Gaps = 63/621 (10%) Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300 S+T P S K ++S + G ++P S LSP + +T+ + GS PS Sbjct: 4024 STTFPSSSGSTGTKLSPARSTTSGLVGESTP--------SRLSPSSTETTTLPGSPTTPS 4075 Query: 2301 RSG----------SRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP------PNKLSQ 2344 S S D+T S PA S + + PG + + LSQ Sbjct: 4076 LSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ 4134 Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404 P TS S ST+++ S + S + QQ+ T + +++ ++ + GL + Sbjct: 4135 EPTTSHSSQGSTEATLSPGSTTAS---SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 4191 Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--TLRRKLEESASF 2462 + ++ L + SS S + E + PSP T +E S ++ Sbjct: 4192 STPTHSSTG-SLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTY 4250 Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 S PSS P T A + L S + S + HSS A G P + ++ + Sbjct: 4251 HS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305 Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582 + S S + LP + + E S S PR + +S++ S ES+ Sbjct: 4306 SP----ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 4361 Query: 2583 KAKSEDEKHVNSI--SGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN---- 2636 H + S T + +A + + SP ++T+ ++ +T Sbjct: 4362 SHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 4421 Query: 2637 -GAESKTLIYQMAPAVSKTEDVWVRIEDCPINN----PRSGRSPTGNTPPVIDSVSEKAN 2691 G+ TL+ A E P+++ P + SP G+T +S + ++ Sbjct: 4422 PGSTETTLLPDNTTASGLLE------ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 4475 Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS----FIQVDAPDQKGTEIKPGQNNPVP 2747 PN KD+ A + V + T + ++ F + E ++PV Sbjct: 4476 PNSKDT--TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4533 Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPT 2807 + T + + S++ HSSP T N + S S S+ I + Sbjct: 4534 TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISS 4593 Query: 2808 PVNNNTKKRDSKTDSTESSGT 2828 + + + T S G+ Sbjct: 4594 APSTTSALVEEPTSYHSSPGS 4614 Score = 53.9 bits (128), Expect = 2e-06 Identities = 132/646 (20%), Positives = 224/646 (34%), Gaps = 56/646 (8%) Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281 IS G T +PG S++T+ +S+K +P S + +TTS ++ S S Sbjct: 3225 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 3280 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339 P + T+ GS+ P S ++ S P + S +S+ P P Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340 Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395 + + L ++ ++ ++S S SP +S T + G S S P S+ Sbjct: 3341 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 3400 Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449 SA L+ ++G+ ++ SST SE + V +T PS Sbjct: 3401 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT----TPS 3456 Query: 2450 P---TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRK 2506 P T +EES ++ S S++ S + S S +TH+ A Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA----- 3511 Query: 2507 LPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRR 2566 P S +E + A +H S SG + + HSS + Sbjct: 3512 -PSTTSALVEEPTSYHSSPGSTATTHFPDSS----TTSGRSEESTASHSSQDATGTIVLP 3566 Query: 2567 TGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNST 2626 S++S+L S +S + E S T + + + + SP ++T Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626 Query: 2627 SQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686 S VS +T + A S T R ++P G + T P + Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP--GSTDTTLLPASTTTS 3684 Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLEN--------RLNSFIQVDAPDQKG--- 2735 S + GS + G E+ ++ + D+ G Sbjct: 3685 GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744 Query: 2736 --TEIKPGQNNP----VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPS 2789 T + +P P S T+ E T F + +S H++PS A Sbjct: 3745 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 3804 Query: 2790 PRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835 R + T+ P+ T + +++K S ++SGT HS Sbjct: 3805 HRSPGSTPTTHFPASSTT--SGHSEKSTIFHSSPDASGTTPSSAHS 3848 Score = 48.5 bits (114), Expect = 9e-05 Identities = 132/631 (20%), Positives = 221/631 (35%), Gaps = 81/631 (12%) Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281 S R H+P SS S + P T + P +TT P ++ S S Sbjct: 641 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 696 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341 SP T+ GS+ A S + SRP + P + S P + Sbjct: 697 SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 753 Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392 ++ P T+ ST G ++ P + + + T + SSIP Sbjct: 754 STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 813 Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445 + S + GL ++ G+ + + +T G ES S + I Sbjct: 814 THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 869 Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505 APS T +EE S+ S SP S + + T S + S ++HSS A G Sbjct: 870 SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTI 923 Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR 2565 LP + ++ + + S S + LP + + E S S PR Sbjct: 924 VLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPR----- 974 Query: 2566 RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS 2625 S ++ LS +S +S SG + S G+ + + T Sbjct: 975 ---SPATTLSPASTTS--------------SGVSEESTTSRSRPGSTHTTAFPDSTTTPG 1017 Query: 2626 TSQ-TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVID 2684 S+ + +S ++ G+ TL+ PA + T P + S +G+T + Sbjct: 1018 LSRHSTTSHSSPGSTDTTLL----PASTTTSG--------PSQESTTSHSSSGSTDTALS 1065 Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744 S A S ++ N T+ ++ +S I V+A + + + Sbjct: 1066 PGSTTAL-----SFGQESTTFHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTT 1119 Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ 2804 P S T+ E T F + +S H++PS A R + T+ P+ Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 1179 Query: 2805 IPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835 T + +++K S ++SGT HS Sbjct: 1180 STT--SGHSEKSTIFHSSPDASGTTPSSAHS 1208 Score = 48.5 bits (114), Expect = 9e-05 Identities = 137/654 (20%), Positives = 234/654 (35%), Gaps = 117/654 (17%) Query: 2239 SSSSTSPVSKKGPPLKT-PASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSK 2297 +S+++S VS++ + P S + ++TT P ++ S S SP + T+ GS+ Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 4407 Query: 2298 APSRSGSRDSTPSRP-------------------AQQPLSRPIQSPGRNSISPG----RN 2334 A S + S P A P+ SP ++SP R Sbjct: 4408 ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP-HTTLSPAGSTTRQ 4466 Query: 2335 GIS---------------PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLT 2379 G S PP S S+ S S S+ + S +S S+++ T Sbjct: 4467 GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 4526 Query: 2380 KQTGLSKNASSIPRSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERP 2435 + A++ + S + GL ++ G+ + + ++T G ES S Sbjct: 4527 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSS 4586 Query: 2436 VLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLST 2495 + I APS T +EE S+ S SP S + + T S + S ++ Sbjct: 4587 T----THTISSAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTAS 4636 Query: 2496 HSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHS 2555 HSS A G LP + ++ + + S S + LP + + E S Sbjct: 4637 HSSQDATGTIVLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSEKSTTF 4692 Query: 2556 SSLPRVSTWRRTGSSSSILSASSESSEKAKS-------------------EDEKHVNSIS 2596 S P + +SS+ L S ES+ S E+ +S Sbjct: 4693 HSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 4752 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSS--GATNGAESKTLIYQMAPAVSKT 2654 G+ Q+ S+ + R E + +ST+ T+SS T+ + Y +P T Sbjct: 4753 GSTQTMHFPESSTASGR--SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT 4810 Query: 2655 EDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMR 2714 P ++ SGRS +S + ++P+ A +G + Sbjct: 4811 THF-------PESSTTSGRSE--------ESTASHSSPDTNGITPLPAHFTT-SGRIAES 4854 Query: 2715 TV------GLENRLNSFIQVDAPDQKGTEIKPGQNNP----VPVSETNESSIVERTPFSS 2764 T +E L S K T + +P P S T+ S E T S Sbjct: 4855 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 4914 Query: 2765 SSSSKHSS--PSGTVAARV----TPFNYNPSPRKSSAD----STSARPSQIPTP 2808 + S H++ P+ T + + T F+ P +++ +TS+ + TP Sbjct: 4915 QAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP 4968 Score = 47.4 bits (111), Expect = 2e-04 Identities = 156/729 (21%), Positives = 256/729 (35%), Gaps = 128/729 (17%) Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253 S++ G+ ++ SG M+ P P +S T H SS SP + Sbjct: 932 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH-------SSPRSPATTL---- 980 Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313 +PAS + S +T+ R S + P + T + S S T PA Sbjct: 981 -SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 1039 Query: 2314 QQPLSRPIQ-------SPGR--NSISPG---------------RNGISPPNKLSQLPRTS 2349 S P Q S G ++SPG N S L TS Sbjct: 1040 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 1099 Query: 2350 S----PSTASTKSSGSGK-----MSYTSPGRQ------MSQQNLTKQTGLSKNASSIPRS 2394 S ST S+GS + S TSPG Q + T T + ++ P Sbjct: 1100 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 1159 Query: 2395 ESA----------SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444 ES + + +G ++K + S S + S +ST Sbjct: 1160 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 1219 Query: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSL------ 2493 + +P T L S + LS + S P SPT + + + S + + S Sbjct: 1220 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 1279 Query: 2494 -STHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR-----HDIARS-HSESPSRL---PINR 2543 STHS+V + T Y+ R + H S H E P+ P + Sbjct: 1280 GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339 Query: 2544 SGTWKREHS------KHSSSLPRVSTWRRTGSSSSILSAS-SESSEKAKSEDEKHVNSIS 2596 T E S + S++ P +TG +++ +A E S S + + Sbjct: 1340 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS-----SGST 1394 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG--AESKTLIY--------Q 2646 GTK S ++ G + + SP+++ + T+ T +E T Y Sbjct: 1395 GTKLSPARSTTS-GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 1453 Query: 2647 MAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNV 2706 ++PA + + V E+ ++ + G + T P + P S + + Sbjct: 1454 LSPATTTSSGV---SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 1510 Query: 2707 GNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVE-RTPFSSS 2765 GS ++G + S +P T + P +T S +VE TP SS Sbjct: 1511 SPGSTTASSLGQQ----STTFHSSPGDTETTLLP--------DDTITSGLVEASTPTHSS 1558 Query: 2766 SSSKHS--SPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT--KKRDSKTD 2821 + S H+ +P+ + +A + + SS+D+T + P PV +T R S T Sbjct: 1559 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1618 Query: 2822 STESSGTQS 2830 +T S + + Sbjct: 1619 TTHFSASST 1627 Score = 43.1 bits (100), Expect = 0.004 Identities = 137/660 (20%), Positives = 232/660 (35%), Gaps = 117/660 (17%) Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253 S++ G+ ++ SG M+ P P +S T H SS SP + P Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH-------SSPRSPATTLSPAS 2067 Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313 T S SE T + S G S + P + T + S S T PA Sbjct: 2068 TT--SSGVSEESTTSHSRPG---STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2122 Query: 2314 QQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSY-TSPGRQ 2372 S P Q + SPG + SP + + S G ++ +SPG Sbjct: 2123 STTTSGPSQESTTSHSSPGSTDTA-----------LSPGSTTALSFGQESTTFHSSPG-- 2169 Query: 2373 MSQQNLTKQTGLSKNASSIPRSESAS---KGLNQMNNGNGANKKVELSRMSSTKS--SGS 2427 S + + P S ++S + ++++ G + + LS SST G Sbjct: 2170 ------------STHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGE 2216 Query: 2428 ESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP------ASPTRSQAQT 2481 + P ST +P T +EES ++ SP S P +S T ++ Sbjct: 2217 STAFQTHPA----STHTTPSPPSTATAPVEESTTYHR-SPGSTPTTHFPASSTTSGHSEK 2271 Query: 2482 PVLSPSLPDMSLSTHSSVQ---AGGWRKLPPNLSP------TIEYNDGRP----AKRHDI 2528 + S PD S +T SS +G +SP T+ + P A Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 2331 Query: 2529 ARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588 + S + + P + + E S S S P GS+ S +S +S ++ E Sbjct: 2332 SSPRSPTTTLSPASMTSLGVGEESTTSRSQP--------GSTHSTVSPASTTTPGLSEES 2383 Query: 2589 EKHVNSISGTKQS----KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644 +S G+ ++ + S +G + + T++T T S T+G ++ Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDS-TTSGLTEESTA 2442 Query: 2645 YQMAPAVSK--------TEDVWVRIEDCPINNPRSGR--SPTGNTPPVIDSVSEKANPNI 2694 + +PA ++ T D+ P ++ +G SP +T + ++ P+ Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST---TSGLVGESTPSR 2499 Query: 2695 KDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNES 2754 + G+ + P L + +F +P + P VSE + + Sbjct: 2500 LSPSSTETTTLPGSPTTP----SLSEKSTTF--YTSPRSPDATLSPATTTSSGVSEESST 2553 Query: 2755 SIVE-------------RTP-FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800 S + TP S S++ HSSP T + P + S S S+ Sbjct: 2554 SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2613 Score = 41.6 bits (96), Expect = 0.011 Identities = 74/358 (20%), Positives = 126/358 (35%), Gaps = 26/358 (7%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 P++ S Y S+ F S ++SG S K+ SS + + T S+A S Sbjct: 3797 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 3856 Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285 SR T S +++ + Y +P +S++SL E+ Sbjct: 3857 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 3916 Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 + G +T S T ++E E S+ +E + T R + ++ S Sbjct: 3917 SQPGSTHSTVSPASTTTPGLSE--ESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHS 3974 Query: 1345 ESARHKAVEFSSGAKSPSKSGAQT--PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIA 1402 A F+ + + + T P SP P + +F S S + Sbjct: 3975 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT-GLPATLTTADLGEESTTFPSSSGS 4033 Query: 1403 SSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPT 1459 + + P SG++ +PS L S +T S T P + + T P++ T Sbjct: 4034 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093 Query: 1460 ---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510 A SG + + + Q PD+ T + E T S S+ + LS Sbjct: 4094 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLS 4151 Score = 40.8 bits (94), Expect = 0.019 Identities = 74/360 (20%), Positives = 134/360 (37%), Gaps = 30/360 (8%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 P++ S Y S+ F S ++SG S K+ SS + + T S+A S Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2773 Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285 SR T S +++ + Y +P +S++SL E+ Sbjct: 2774 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2833 Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 + G +T S T ++E + + S + V PR+ ++ ++G ++ Sbjct: 2834 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV-----FPRSTTTSVRGEEPTT 2888 Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400 +R + + + + SG ++ P +T L + T+ +S F S S Sbjct: 2889 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2948 Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457 ++ P SG++ +PS L S +T S T P + + T P++ Sbjct: 2949 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 3008 Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510 T A SG + + + Q PD+ T + E T S S+ + LS Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLS 3068 Score = 40.4 bits (93), Expect = 0.025 Identities = 71/350 (20%), Positives = 129/350 (36%), Gaps = 25/350 (7%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 P++ S Y S+ F S ++SG S K+ SS + + T S+A S Sbjct: 2240 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2299 Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285 SR T S +++ + Y +P +S++SL E+ Sbjct: 2300 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2359 Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 + G +T S T ++E + + S + V PRT ++ ++G ++ Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV-----FPRTPTTSVRGEEPTT 2414 Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400 +R + + + + SG ++ P +T L + T+ +S F S S Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2474 Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457 ++ P SG++ +PS L S +T S T P + + T P ++ Sbjct: 2475 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP--RS 2532 Query: 1458 PTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLS 1507 P A + + V+ P + F +T G S S+ S Sbjct: 2533 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS 2582 Score = 39.7 bits (91), Expect = 0.043 Identities = 73/360 (20%), Positives = 133/360 (36%), Gaps = 30/360 (8%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 P++ S Y S+ F S ++SG S K+ SS + + T S+A S Sbjct: 1157 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 1216 Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285 SR T S +++ + Y +P +S++SL E+ Sbjct: 1217 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 1276 Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 + G +T S T ++E + + S + V P + ++ + G ++ Sbjct: 1277 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTT 1331 Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400 +R + + + + SG ++ P +T L + T+ +S F S S Sbjct: 1332 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 1391 Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457 ++ + P SG++ +PS L S +T S T P + + T P++ Sbjct: 1392 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 1451 Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510 T A SG + + + Q PD+ T + E T S S+ + LS Sbjct: 1452 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511 Score = 39.7 bits (91), Expect = 0.043 Identities = 78/355 (21%), Positives = 131/355 (36%), Gaps = 56/355 (15%) Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQ------------------ 1230 S+ FS S ++ G+S ++ + SS T+T S A+ Sbjct: 4505 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQT 4564 Query: 1231 LHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCN 1290 +H + + SG+ +++ T S+ T+ + P S + + +S G Sbjct: 4565 MHFPESNTTSGRGEESTTSHSST-------THTISSAPSTTS--ALVEEPTSYHSSPGST 4615 Query: 1291 QTTQEADSANTLQIAEIKEKIGTRSAEDPVSEV--PAVSQHPRTKSSRLQGSS----LSS 1344 TT DS+ T +E E + S++D + PA R+ +S L G S +SS Sbjct: 4616 ATTHFPDSSTTSGRSE--ESTASHSSQDATGTIVLPA-----RSTTSVLLGESTTSPISS 4668 Query: 1345 ESARHKAVEFSS---GAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401 S A+ S+ G S + +P S P + + R +++ S + Sbjct: 4669 GSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTV---HSSPV 4725 Query: 1402 ASSVQSEPCSGMVSGIISPSD-LPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTA 1460 A++ P SG++ S SPG T P TA + E + + Sbjct: 4726 ATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHF-----PESSTASGRSEESRTSHSST 4780 Query: 1461 EKRESGPKQAAVNAAVQR---VQVLPDADTLLHFATESTPDGFSCSSSLSALSLD 1512 S P + +A V+ P + HF ST G S S+ S S D Sbjct: 4781 THTISSP-PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 4834 Score = 36.6 bits (83), Expect = 0.36 Identities = 78/382 (20%), Positives = 134/382 (35%), Gaps = 56/382 (14%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++SG+S S+T H S++ +S PS+ + + P+ Sbjct: 1909 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 1966 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+ ++ +D P + L ++ Sbjct: 1967 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 2023 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336 + G +TT S T ++E + + PA VS+ T SR Sbjct: 2024 SPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 2083 Query: 1337 --------LQGSSLSSESARHKAVEFSSGAKS-------------PSKSGAQTPKSPPEH 1375 S+ + +RH SS + PS+ + SP Sbjct: 2084 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143 Query: 1376 YVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431 +P + + +F S ++ P S SGI+ S SP T+ Sbjct: 2144 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203 Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490 P+ S +P TA + P+ + P + + P + H Sbjct: 2204 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 2258 Query: 1491 FATESTPDGFSCSSSLSALSLD 1512 F ST G S S++ S D Sbjct: 2259 FPASSTTSGHSEKSTIFHSSPD 2280 Score = 35.4 bits (80), Expect = 0.81 Identities = 61/272 (22%), Positives = 99/272 (36%), Gaps = 27/272 (9%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++S G+ S T H S++ +S PS+ + + P+ Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 3523 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+ ++ +D P + L ++ Sbjct: 3524 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 3580 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSL 1342 + G +TT S T ++E T P S +S T S + S+ Sbjct: 3581 SPISSGSMETTALPGSTTTPGLSE----KSTTFHSSPRSPATTLSPASTTSSGVSEESTT 3636 Query: 1343 S-SESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401 S S F +P S T T L S TS SS +S S S Sbjct: 3637 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSS 3696 Query: 1402 ASSVQSEPCSGMVSGII---SPSDLPDSPGQT 1430 + S + G + + + SPG T Sbjct: 3697 SGSTDTALSPGSTTALSFGQESTTFHSSPGST 3728 Score = 35.0 bits (79), Expect = 1.1 Identities = 57/268 (21%), Positives = 104/268 (38%), Gaps = 26/268 (9%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++S G+ S T H S++ +S PS+ + + P+ Sbjct: 4549 VEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 4606 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+ ++ +D P + L ++ Sbjct: 4607 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 4663 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQ--HPRTKSSRLQGS 1340 + G +TT S T ++E + + P + A S +S+ + S Sbjct: 4664 SPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSS 4723 Query: 1341 SLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS 1400 +++ + A +SG S + +P S + E S S S +S S S Sbjct: 4724 PVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE-----SSTASGRSEESRTSHS 4778 Query: 1401 IASSVQSEPCSGMVSGIISPSDLPDSPG 1428 + S P S + + P+ SPG Sbjct: 4779 STTHTISSPPSTTSALVEEPTSYHSSPG 4806 Score = 34.3 bits (77), Expect = 1.8 Identities = 59/282 (20%), Positives = 108/282 (38%), Gaps = 45/282 (15%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232 P++ S Y + S+ FS S ++ G+S ++ + SS T T P+ +A Sbjct: 3160 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 3219 Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289 P+++ SG + A + + +++++ Y +P ++LS S+ + Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 3274 Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349 TT + +T A G+ + E A P + + L S ++ S Sbjct: 3275 ESTTSHSRPGSTHTTA----FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 3330 Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409 ++ F SG S ET L+ T+ L++ S + SS Sbjct: 3331 ESTTFHSGPGS-----------------TETTLLPDNTTASGLLEA--STPVHSS----- 3366 Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446 +G +SP+ G Q+ P S+ TP PP T+ Sbjct: 3367 -TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407 Score = 33.9 bits (76), Expect = 2.4 Identities = 81/382 (21%), Positives = 135/382 (35%), Gaps = 56/382 (14%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++S G+ S T H S++ +S PS+ + + P+ Sbjct: 826 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 883 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+ ++ +D P + L ++ Sbjct: 884 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336 + G +TT S T ++E + + PA VS+ T SR Sbjct: 941 SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSR 1000 Query: 1337 --------LQGSSLSSESARHKAVEFSS-GAKSPSKSGAQTPKSPPEHY---------VQ 1378 S+ + +RH SS G+ + A T S P Sbjct: 1001 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST 1060 Query: 1379 ETPLMFSRCTSVS---SLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431 +T L T++S +F S ++ P S SGI+ S SP T+ Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 1120 Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490 P+ S +P TA + P+ + P + + P + H Sbjct: 1121 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 1175 Query: 1491 FATESTPDGFSCSSSLSALSLD 1512 F ST G S S++ S D Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPD 1197 Score = 33.5 bits (75), Expect = 3.1 Identities = 79/347 (22%), Positives = 126/347 (36%), Gaps = 56/347 (16%) Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK--------RQNQLHPSSAQSRS 1240 S+ FS S ++ G+S ++ + SS T+T S A+ H S +++ Sbjct: 1865 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQT 1924 Query: 1241 GQPQKAATCKVSSINQETIQ---TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEAD 1297 +++T S T T+ + P S + + +S G TT D Sbjct: 1925 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS--ALVEEPTSYHSSPGSTATTHFPD 1982 Query: 1298 SANTLQIAEIKEKIGTRSAEDPVSEV--PAVSQHPRTKSSRLQGSSLSSESARHKAVEFS 1355 S+ T +E E + S++D + PA R+ +S L G S + Sbjct: 1983 SSTTSGRSE--ESTASHSSQDATGTIVLPA-----RSTTSVLLGESTT------------ 2023 Query: 1356 SGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVS 1415 SP SG+ + P TP + + T +F S + + P S S Sbjct: 2024 ----SPISSGSMETTALPGS--TTTPGLSEKST------TFHSSPRSPATTLSPASTTSS 2071 Query: 1416 GIISPSDLPDS-PGQTMPPS--RSKTPPPPPQTAQTKREVPKNKAPT---AEKRESGPKQ 1469 G+ S S PG T + S T P + + T P + T A SGP Q Sbjct: 2072 GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQ 2131 Query: 1470 AAVNA----AVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLD 1512 + + + P + T L F EST S S+ + L D Sbjct: 2132 ESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2178 Score = 33.5 bits (75), Expect = 3.1 Identities = 64/340 (18%), Positives = 122/340 (35%), Gaps = 23/340 (6%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQL---HP 1233 ++ Y + S+ F S ++SG+S ++ SS + T T A+ + Sbjct: 3519 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 3578 Query: 1234 SSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI--- 1287 +++ SG + A + +++++ + +P +S +S +E+ Sbjct: 3579 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 3638 Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 G TT DS T ++ + T S P S + T S Q S+ S Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSH 3694 Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404 S+ S G+ + G ++ T L TS +++ S + SS Sbjct: 3695 SSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA--STRVHSS 3752 Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462 S + + SP +S P+ + T P PP TA + +++P + Sbjct: 3753 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 3812 Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499 P + + ++ + PDA + ST G Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 3852 Score = 33.5 bits (75), Expect = 3.1 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++SG+S S+T H S++ +S PS+ + + P+ Sbjct: 4742 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 4799 Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278 S S G P+ + T + S+ + + T + P F+ ++ Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 4859 Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338 S S E + TT + +T+ + +RS + +S S + + L Sbjct: 4860 SPGSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 4913 Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396 + S+ + A +SG S + P S ET L T+ S F Sbjct: 4914 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 4967 Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430 S+ ++ P S V G+ S SPG T Sbjct: 4968 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 5003 Score = 33.1 bits (74), Expect = 4.0 Identities = 68/340 (20%), Positives = 115/340 (33%), Gaps = 23/340 (6%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-------QN 1229 ++ Y + S+ F S ++SG+S ++ SS + T T A+ ++ Sbjct: 879 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 938 Query: 1230 QLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI-- 1287 P S+ S +T + T S S+ SS S E Sbjct: 939 TTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 998 Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 G TT DS T ++ + T S P S + T S Q S+ S Sbjct: 999 SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 1054 Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404 S+ S G+ + G ++ T L TS +++ S + SS Sbjct: 1055 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA--STRVHSS 1112 Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462 S + + SP +S P+ + T P PP TA + +++P + Sbjct: 1113 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 1172 Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499 P + + ++ + PDA + ST G Sbjct: 1173 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 1212 Score = 32.7 bits (73), Expect = 5.2 Identities = 60/305 (19%), Positives = 114/305 (37%), Gaps = 30/305 (9%) Query: 1216 ENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCS 1275 E+T+ PSS+ +L P+ + + SG ++ ++S + ET TP + + Sbjct: 4023 ESTTFPSSSGSTGTKLSPARSTT-SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 4081 Query: 1276 SLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSS 1335 + + + D TT + + + + +A + +SQ P T S Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141 Query: 1336 RLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDS 1395 QGS+ ++ S G+ + S G Q+ ET L+ D+ Sbjct: 4142 S-QGSTEAT---------LSPGSTTASSLGQQSTTFHSSPGDTETTLLPD--------DT 4183 Query: 1396 FESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMP------PSRSKTPPPPPQTAQTK 1449 S + +S + +G + ++P+ + Q PS S T P PP T Sbjct: 4184 ITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT--- 4240 Query: 1450 REVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSAL 1509 VP + T R S +A+ + + T +H + +T + S +++ Sbjct: 4241 -AVPVEVSTTYHSRPSSTPTTHFSASSTTLG-RSEESTTVHSSPGATGTALFPTRSATSV 4298 Query: 1510 SLDEP 1514 + EP Sbjct: 4299 LVGEP 4303 Score = 32.3 bits (72), Expect = 6.9 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232 P++ S Y + S+ FS S ++ G+S ++ + SS T T P+ +A Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662 Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289 P+++ SG + A + + +++++ Y +P ++LS S+ + Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 1717 Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349 TT + +T +A + +P VSQ S+ S S Sbjct: 1718 ESTTSHSRPGST-----------HTTAFPGSTTMPGVSQE----------STASHSSPGS 1756 Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409 S G+ + S G ++ ET L+ T+ L++ S + SS Sbjct: 1757 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 1809 Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446 +G +SP+ G Q+ P S+ P PP T+ Sbjct: 1810 -TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1850 Score = 32.3 bits (72), Expect = 6.9 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232 P++ S Y + S+ FS S ++ G+S ++ + SS T T P+ +A Sbjct: 4243 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 4302 Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289 P+++ SG + A + + +++++ Y +P ++LS S+ + Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 4357 Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349 TT + + +A + +P VSQ S+ S S Sbjct: 4358 ESTTSHSRPGSM-----------HTTAFPSSTTMPGVSQE----------STASHSSPGS 4396 Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409 S G+ + S G ++ ET L+ T+ L++ S + SS Sbjct: 4397 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 4449 Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446 +G +SP+ G Q+ P S+ TP PP T+ Sbjct: 4450 -TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 4490 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 65.9 bits (159), Expect = 6e-10 Identities = 161/764 (21%), Positives = 274/764 (35%), Gaps = 88/764 (11%) Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182 S+++++ S S + +S GS L+ QE F SN G ST + +E Sbjct: 534 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 593 Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224 S S G++G +++ + S S ++ Sbjct: 594 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 653 Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283 S G T H P +SS+TS S+K + S + +A ++ G S S +S Sbjct: 654 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 709 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ-----QPLSRPIQSPGRNSIS----PGRN 2334 P + + + + GS+ P S + + S P P S G S + PG Sbjct: 710 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 769 Query: 2335 GISPPNKLSQLPRTSSPSTASTKSS-GSGKMSYTSPGRQMSQQNLTKQTGLSKNAS---S 2390 + + P S ST SS GS + + S T S+ AS + Sbjct: 770 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 829 Query: 2391 IPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEA 2447 + +S + GL + + G+ A+ + L +T G ES ST K + Sbjct: 830 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTKLS 886 Query: 2448 PSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTHSS 2498 P+ + L ++ LSPSS P SPT ++ T SP PD +LS ++ Sbjct: 887 PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 946 Query: 2499 VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL 2558 +G +S + +P H A S + S L + + + S ++ Sbjct: 947 TSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998 Query: 2559 PRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKEN 2618 P +T G S+ +S +E D+ SG ++ S+ G+ Sbjct: 999 PGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH----- 1050 Query: 2619 EFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGN 2678 T+ T +S + G + ++ +Q P+ S T P+ + S + Sbjct: 1051 -------TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1103 Query: 2679 TPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE 2737 TP S S ++S + + G P R+ + + V P Sbjct: 1104 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSPIS 1156 Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKSSA 2795 + +P S T + T F SS S + SP+ T ++ V+ + R S Sbjct: 1157 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1216 Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839 +T+ S V+ + S ST++ T SP + S L Sbjct: 1217 HTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 1258 Score = 57.8 bits (138), Expect = 2e-07 Identities = 132/625 (21%), Positives = 232/625 (37%), Gaps = 71/625 (11%) Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300 S+T P S K ++S + G ++P S LSP + +T+ + GS PS Sbjct: 871 STTFPSSSGSTGTKLSPARSTTSGLVGESTP--------SRLSPSSTETTTLPGSPTTPS 922 Query: 2301 RSG----------SRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP------PNKLSQ 2344 S S D+T S PA S + + PG + + LSQ Sbjct: 923 LSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQ 981 Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404 P TS S ST+++ S + S + QQ+ T + +++ ++ + GL + Sbjct: 982 EPTTSHSSQGSTEATLSPGSTTAS---SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 1038 Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--TLRRKLEESASF 2462 + ++ L + SS S + E + PSP T +E S ++ Sbjct: 1039 STPTHSSTG-SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY 1097 Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 S PSS P T A + L S + S + HSS A G P + ++ + Sbjct: 1098 HS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPTRSATSVLVGEPTT 1152 Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582 + S S + LP + + E S S PR + +S++ S ES+ Sbjct: 1153 SP----ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 1208 Query: 2583 KAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN----GA 2638 H + G+ + G ++ + SP ST T+S G+T G Sbjct: 1209 SHSRPGSTHTTAFPGS-------TTMPGVSQESTASHSSP-GSTDTTLSPGSTTASSLGP 1260 Query: 2639 ESKTLIYQMAPAVSKTEDV-------WVRIEDCPINN----PRSGRSPTGNTPPVIDSVS 2687 ES T + +P ++T + + P+++ P + SP G+T +S + Sbjct: 1261 ESTT--FHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318 Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS----FIQVDAPDQKGTEIKPGQN 2743 ++ P+ KD+ A + V + T + ++ F + E + Sbjct: 1319 FQSWPSSKDTMP--APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 1376 Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPS 2803 +PV + T + + S++ HSSP T + + S S S+ Sbjct: 1377 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1436 Query: 2804 QIPTPVNNNTKKRDSKTDSTESSGT 2828 I +P + + + T S G+ Sbjct: 1437 TISSPPSTTSALVEEPTSYHSSPGS 1461 Score = 52.4 bits (124), Expect = 6e-06 Identities = 134/632 (21%), Positives = 224/632 (35%), Gaps = 93/632 (14%) Query: 2254 KTPASKSPSEGQTATTSPRGAKPSV------KSELSPVARQTSQIGGSSKAP---SRSGS 2304 ++ AS S + T P G+ PSV S +S + +T+ + GS+ P +S + Sbjct: 66 ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 125 Query: 2305 RDSTPSRPAQQPLSRPIQSPGRNSIS------PGRNGISPPNKLSQLPRTSSPSTASTKS 2358 S+P P L + S G + S PG + + +P S STAS S Sbjct: 126 FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 185 Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGL-----SKNASSIPRSESASKGLNQMN---NGNGA 2410 G + SPG + + T S + +P + +AS GL + + + + Sbjct: 186 PGPTDTT-LSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS-GLLEASMPVHSSTR 243 Query: 2411 NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSR 2470 + LS ST G + P S + AP PT E ++ SPSS Sbjct: 244 SPHTTLSPAGSTTRQGESTTFHSWP----SSKDTRPAP-PTTTSAFVEPSTTSHGSPSSI 298 Query: 2471 PASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY--NDGRPAKRHDI 2528 P + +++ T L + S + HSS P + T+ + +D + + Sbjct: 299 PTTHISARSTT----SGLVEESTTYHSS----------PGSTQTMHFPESDTTSGRGEES 344 Query: 2529 ARSHSESP---SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585 SHS + S P S + S HSS P + SS+ S ES+ Sbjct: 345 TTSHSSTTHTISSAPSTTSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESTASHS 402 Query: 2586 SEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG-----ATNGAES 2640 S+D +I +S + + + T I T T + G T + Sbjct: 403 SQDA--TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 460 Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS-----PTGNTPPVID--SVSEKANPN 2693 ++ ++PA + + V E+ + R G + P T P + S + ++P Sbjct: 461 RSPATTLSPASTTSSGV---SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 517 Query: 2694 IKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNE 2753 D+ +P T S + T + PG + + Sbjct: 518 STDTT-----------LLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQ--- 563 Query: 2754 SSIVERTPFSSSSSSKH-------SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIP 2806 E T F S+ S H ++ SG V A + SPR + + ++S P Sbjct: 564 ----ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 619 Query: 2807 TPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838 T + T + S +P S +Y Sbjct: 620 ESTAFQTHPASTHTTPSPPSTATAPVEESTTY 651 Score = 48.5 bits (114), Expect = 9e-05 Identities = 132/631 (20%), Positives = 221/631 (35%), Gaps = 81/631 (12%) Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281 S R H+P SS S + P T + P +TT P ++ S S Sbjct: 128 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 183 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341 SP T+ GS+ A S + SRP + P + S P + Sbjct: 184 SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 240 Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392 ++ P T+ ST G ++ P + + + T + SSIP Sbjct: 241 STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 300 Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445 + S + GL ++ G+ + + +T G ES S + I Sbjct: 301 THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 356 Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505 APS T +EE S+ S SP S + + T S + S ++HSS A G Sbjct: 357 SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTI 410 Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR 2565 LP + ++ + + S S + LP + + E S S PR Sbjct: 411 VLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPR----- 461 Query: 2566 RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS 2625 S ++ LS +S +S SG + S G+ + + T Sbjct: 462 ---SPATTLSPASTTS--------------SGVSEESTTSRSRPGSTHTTAFPDSTTTPG 504 Query: 2626 TSQ-TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVID 2684 S+ + +S ++ G+ TL+ PA + T P + S +G+T + Sbjct: 505 LSRHSTTSHSSPGSTDTTLL----PASTTTSG--------PSQESTTSHSSSGSTDTALS 552 Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744 S A S ++ N T+ ++ +S I V+A + + + Sbjct: 553 PGSTTAL-----SFGQESTTFHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTT 606 Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ 2804 P S T+ E T F + +S H++PS A R + T+ P+ Sbjct: 607 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 666 Query: 2805 IPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835 T + +++K S ++SGT HS Sbjct: 667 STT--SGHSEKSTIFHSSPDASGTTPSSAHS 695 Score = 47.4 bits (111), Expect = 2e-04 Identities = 156/729 (21%), Positives = 256/729 (35%), Gaps = 128/729 (17%) Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253 S++ G+ ++ SG M+ P P +S T H SS SP + Sbjct: 419 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH-------SSPRSPATTL---- 467 Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313 +PAS + S +T+ R S + P + T + S S T PA Sbjct: 468 -SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 526 Query: 2314 QQPLSRPIQ-------SPGR--NSISPG---------------RNGISPPNKLSQLPRTS 2349 S P Q S G ++SPG N S L TS Sbjct: 527 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 586 Query: 2350 S----PSTASTKSSGSGK-----MSYTSPGRQ------MSQQNLTKQTGLSKNASSIPRS 2394 S ST S+GS + S TSPG Q + T T + ++ P Sbjct: 587 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 646 Query: 2395 ESA----------SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444 ES + + +G ++K + S S + S +ST Sbjct: 647 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 706 Query: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSL------ 2493 + +P T L S + LS + S P SPT + + + S + + S Sbjct: 707 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 766 Query: 2494 -STHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR-----HDIARS-HSESPSRL---PINR 2543 STHS+V + T Y+ R + H S H E P+ P + Sbjct: 767 GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 826 Query: 2544 SGTWKREHS------KHSSSLPRVSTWRRTGSSSSILSAS-SESSEKAKSEDEKHVNSIS 2596 T E S + S++ P +TG +++ +A E S S + + Sbjct: 827 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS-----SGST 881 Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG--AESKTLIY--------Q 2646 GTK S ++ G + + SP+++ + T+ T +E T Y Sbjct: 882 GTKLSPARSTTS-GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 940 Query: 2647 MAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNV 2706 ++PA + + V E+ ++ + G + T P + P S + + Sbjct: 941 LSPATTTSSGV---SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 997 Query: 2707 GNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVE-RTPFSSS 2765 GS ++G + S +P T + P +T S +VE TP SS Sbjct: 998 SPGSTTASSLGQQ----STTFHSSPGDTETTLLP--------DDTITSGLVEASTPTHSS 1045 Query: 2766 SSSKHS--SPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT--KKRDSKTD 2821 + S H+ +P+ + +A + + SS+D+T + P PV +T R S T Sbjct: 1046 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1105 Query: 2822 STESSGTQS 2830 +T S + + Sbjct: 1106 TTHFSASST 1114 Score = 45.4 bits (106), Expect = 8e-04 Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 37/308 (12%) Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281 IS G T +PG S++T+ +S+K +P S + +TTS ++ S S Sbjct: 1155 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1210 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339 P + T+ GS+ P S ++ S P + S +S+ P SP Sbjct: 1211 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1270 Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395 + + L ++ ++ ++S S SP +S T + G S S P S+ Sbjct: 1271 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1330 Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432 SA L+ ++G+ ++ SST SE RS Sbjct: 1331 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1390 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490 LV +ST +P T ES++ S SR +S T + + P + +L + Sbjct: 1391 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1450 Query: 2491 MSLSTHSS 2498 S HSS Sbjct: 1451 EPTSYHSS 1458 Score = 43.5 bits (101), Expect = 0.003 Identities = 87/442 (19%), Positives = 165/442 (37%), Gaps = 51/442 (11%) Query: 2425 SGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL 2484 S + S SE ST ++ +P+ L ++ SL + T + + + Sbjct: 6 SSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET----THFRDSSTIS 61 Query: 2485 SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRS 2544 S + S ++HSS A LP +P++ D P+ S S + LP + + Sbjct: 62 GRS--EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSP----ISSGSMETTALPGSTT 115 Query: 2545 GTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISG--TKQSK 2602 E S S PR +S + S ES+ H + G T Sbjct: 116 KPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL 175 Query: 2603 ENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN-----GAESKTLIYQMAPAVSKTEDV 2657 + +A + + SP ++T+ ++ T G+ TL+ A E Sbjct: 176 SQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE-- 233 Query: 2658 WVRIEDCPIN----NPRSGRSPTGNTPPVIDSVSEKANPNIKDSK-----------DNQA 2702 P++ +P + SP G+T +S + + P+ KD++ + Sbjct: 234 ----ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 289 Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF 2762 + S+P + + + ++ + PG + E++ +S Sbjct: 290 TSHGSPSSIPTTHISARSTTSGLVE----ESTTYHSSPGSTQTMHFPESDTTSGRGEEST 345 Query: 2763 SSSSSSKH---SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSK 2819 +S SS+ H S+PS T A P +Y+ SP + +T+ P T + +++ + Sbjct: 346 TSHSSTTHTISSAPSTTSALVEEPTSYHSSP---GSTATTHFPDSSTT--SGRSEESTAS 400 Query: 2820 TDSTESSGT-QSPKRHSGSYLV 2840 S +++GT P R + S L+ Sbjct: 401 HSSQDATGTIVLPARSTTSVLL 422 Score = 39.7 bits (91), Expect = 0.043 Identities = 73/360 (20%), Positives = 133/360 (36%), Gaps = 30/360 (8%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235 P++ S Y S+ F S ++SG S K+ SS + + T S+A S Sbjct: 644 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 703 Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285 SR T S +++ + Y +P +S++SL E+ Sbjct: 704 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 763 Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 + G +T S T ++E + + S + V P + ++ + G ++ Sbjct: 764 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTT 818 Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400 +R + + + + SG ++ P +T L + T+ +S F S S Sbjct: 819 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 878 Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457 ++ + P SG++ +PS L S +T S T P + + T P++ Sbjct: 879 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 938 Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510 T A SG + + + Q PD+ T + E T S S+ + LS Sbjct: 939 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998 Score = 33.9 bits (76), Expect = 2.4 Identities = 81/382 (21%), Positives = 135/382 (35%), Gaps = 56/382 (14%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++S G+ S T H S++ +S PS+ + + P+ Sbjct: 313 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 370 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+ ++ +D P + L ++ Sbjct: 371 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 427 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336 + G +TT S T ++E + + PA VS+ T SR Sbjct: 428 SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSR 487 Query: 1337 --------LQGSSLSSESARHKAVEFSS-GAKSPSKSGAQTPKSPPEHY---------VQ 1378 S+ + +RH SS G+ + A T S P Sbjct: 488 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST 547 Query: 1379 ETPLMFSRCTSVS---SLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431 +T L T++S +F S ++ P S SGI+ S SP T+ Sbjct: 548 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 607 Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490 P+ S +P TA + P+ + P + + P + H Sbjct: 608 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 662 Query: 1491 FATESTPDGFSCSSSLSALSLD 1512 F ST G S S++ S D Sbjct: 663 FPASSTTSGHSEKSTIFHSSPD 684 Score = 33.9 bits (76), Expect = 2.4 Identities = 123/643 (19%), Positives = 218/643 (33%), Gaps = 45/643 (6%) Query: 1895 TSHTELTSNQQSANKTQAIAKQPINRGQPKPI-LQKQSTFPQSSKDIPDRGAATDEKLQN 1953 T+ ++L+ +++ +Q + ++ G L +QST SS + D+ + + Sbjct: 974 TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1033 Query: 1954 FAIE-NTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSF 2012 +E +TP S S ++L+ + + E P S P + AP Sbjct: 1034 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP--- 1090 Query: 2013 HVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSA-------------MPKKKKPSRLKGD 2059 VE + SR SS + + L S P + S L G+ Sbjct: 1091 -VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1149 Query: 2060 NEKHSPRNMGG-----ILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSS 2114 SP + G + G T L + SPD+ G + ++ Sbjct: 1150 PTT-SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 1208 Query: 2115 LHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT-SNKGPRIL----K 2169 H + + S + +S +S S SP T S+ GP Sbjct: 1209 SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 1268 Query: 2170 PGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQM-KQPLQANMPSISRGR 2228 PG T + S ++ V+ S TG + +G +Q S + Sbjct: 1269 PGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGESTTFQSWPSSK 1326 Query: 2229 TMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTA-----TTSPRGAKPSVKSELS 2283 + P S+ + G P TP + + T +T+ + + + S Sbjct: 1327 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1386 Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343 P TS + S A S T P S + + S SPP+ S Sbjct: 1387 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1446 Query: 2344 QLPR--TSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNA-SSIPRSESASKG 2400 L TS S+ + ++ S T+ GR S+++ + N + +P + S Sbjct: 1447 ALVEEPTSYHSSPGSIATTHFPESSTTSGR--SEESTASHSSPDTNGITPLPAHFTTSGR 1504 Query: 2401 LNQMNNG--NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEE 2458 + + + + + L+ ++T ++S LV + T +PSPT Sbjct: 1505 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPA 1564 Query: 2459 SASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQA 2501 S+S L+ S + S T V + SL ++ T + A Sbjct: 1565 SSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPETPEKLNA 1607 Score = 33.1 bits (74), Expect = 4.0 Identities = 68/340 (20%), Positives = 115/340 (33%), Gaps = 23/340 (6%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-------QN 1229 ++ Y + S+ F S ++SG+S ++ SS + T T A+ ++ Sbjct: 366 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 425 Query: 1230 QLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI-- 1287 P S+ S +T + T S S+ SS S E Sbjct: 426 TTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 485 Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344 G TT DS T ++ + T S P S + T S Q S+ S Sbjct: 486 SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 541 Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404 S+ S G+ + G ++ T L TS +++ S + SS Sbjct: 542 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA--STRVHSS 599 Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462 S + + SP +S P+ + T P PP TA + +++P + Sbjct: 600 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 659 Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499 P + + ++ + PDA + ST G Sbjct: 660 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 699 Score = 32.3 bits (72), Expect = 6.9 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%) Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232 P++ S Y + S+ FS S ++ G+S ++ + SS T T P+ +A Sbjct: 1090 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1149 Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289 P+++ SG + A + + +++++ Y +P ++LS S+ + Sbjct: 1150 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 1204 Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349 TT + +T +A + +P VSQ S+ S S Sbjct: 1205 ESTTSHSRPGST-----------HTTAFPGSTTMPGVSQE----------STASHSSPGS 1243 Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409 S G+ + S G ++ ET L+ T+ L++ S + SS Sbjct: 1244 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 1296 Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446 +G +SP+ G Q+ P S+ P PP T+ Sbjct: 1297 -TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1337 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 65.5 bits (158), Expect = 7e-10 Identities = 130/636 (20%), Positives = 209/636 (32%), Gaps = 106/636 (16%) Query: 2252 PLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR 2311 P TP + P+ Q TT R + + S S G S + S TP Sbjct: 1198 PPTTP--QPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLL 1255 Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK-----SSGSGKMSY 2366 PA S+P S G P P S LP T++ + +TK ++ S Sbjct: 1256 PATLTSSKPTASSGE---PPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAST 1312 Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKV--ELSRMSSTKS 2424 SP + Q+ T+ T ++ S + K NQ G A + + S+T Sbjct: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372 Query: 2425 SGSESDRSERPVLVR--QSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTP 2482 + + + RP Q+ E +P + S PS+ P + T A T Sbjct: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432 Query: 2483 VLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPIN 2542 +PS P+ +L TH +PP + + P+ I +H++ Sbjct: 1433 YPTPSHPETTLPTH----------VPPFSTSLV-----TPSTHTVITPTHAQ-------- 1469 Query: 2543 RSGTWKREHSKHSSSLPRVSTWRRTGS-----------SSSILSASSESSEKAKSEDEKH 2591 T HS + ++P +T + TGS S + + SS S+ K + H Sbjct: 1470 -MATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSH 1528 Query: 2592 VNSI-------SGTKQSKENQVSAKGTWRKIKENE------------FSPTNSTSQTVSS 2632 +S + T N S + N SP +S S+ Sbjct: 1529 TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSST 1588 Query: 2633 GATNGAESKTLIYQMAPA------------------VSKTEDVWVRIEDCPINNPRSGRS 2674 G KT P+ T V + Sbjct: 1589 GPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM 1648 Query: 2675 PTGNTPP-----VIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVD 2729 PTG PP S + S +QA ++ + L + +S + Sbjct: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKT---STSLHSHTSSTHHAE 1705 Query: 2730 APDQKGTEIKPG--QNNPVPVSETNESSIVERTPFSS----------SSSSKHSSPSGTV 2777 A T I P P++ T + R+ FS+ +SS+ H + T Sbjct: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765 Query: 2778 AARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT 2813 +TP + + R A +TSA S++PTP ++ Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHS 1801 Score = 53.1 bits (126), Expect = 4e-06 Identities = 135/690 (19%), Positives = 243/690 (35%), Gaps = 133/690 (19%) Query: 2225 SRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSP 2284 S RT + +P ++S TSP K + P + + T TT PR S +P Sbjct: 1323 STTRTTMTLP--TPATSGTSPTLPKSTNQELPGTTA-----TQTTGPRPTPASTTGPTTP 1375 Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRP----------AQQPLSRPIQSPGRNSISPGRN 2334 Q ++ + +R+ + +TP P + P + P+ + ++ + Sbjct: 1376 QPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPT 1435 Query: 2335 GISPPNKLSQ----------LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGL 2384 P L P T + T + + ++++P + K TG Sbjct: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGS 1495 Query: 2385 SKNA----------SSIPRSESASKGLNQMNNGNGANKKVELSRMSSTK-SSGSESDRSE 2433 + A S S S +K +++ + E++ S+T + S R+ Sbjct: 1496 THTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR 1555 Query: 2434 RPVLVRQSTFIKEAPSP-TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMS 2492 PV S P P T S+ F S+ P + T + T +PS P + Sbjct: 1556 TPVAHTNSATSSRPPPPFTTHSPPTGSSPFS----STGPMTATSFKTTTTYPTPSHPQTT 1611 Query: 2493 LSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHS 2552 L TH +PP + + P+ I +H++ + I HS Sbjct: 1612 LPTH----------VPPFSTSLV-----TPSTHTVITPTHAQMATSASI---------HS 1647 Query: 2553 KHSSSLPRVSTWRRTGSS----SSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSA 2608 + ++P +T + TGS+ + L+ S S + K S+ S + + Sbjct: 1648 MPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEAT 1707 Query: 2609 KGTWRKIKENEFS--------PTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVR 2660 + I N S T+ TSQ+ SS +T A++ T ++ + E Sbjct: 1708 STSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFST--AKTSTSLHSHTSSTHHPEVTSTS 1765 Query: 2661 IEDCPINNPRSG-RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLE 2719 N+ +G R+P +T + S P S G+ P+ + G Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSA--TSSRLPTPFTTHSPP--------TGTTPISSTG-- 1813 Query: 2720 NRLNSFIQVDAPDQKGTEIKPGQNNP-------VP------VSETNESSIVERTPFSSSS 2766 V A + T P ++P VP V+ + + I+ ++S Sbjct: 1814 -------PVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866 Query: 2767 SSKHSSPSGTV----AARVTPFNYNPSPRKSSADSTSARPSQIPT-------PVNNNTKK 2815 +S HS P+GT+ + T + P + TS PS T P + ++ Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH 1926 Query: 2816 RDSKTDST--------ESSGTQSPKRHSGS 2837 T ++ S+GT++P H+ S Sbjct: 1927 HPEVTPTSTTNITPKHTSTGTRTPVAHTTS 1956 Score = 52.8 bits (125), Expect = 5e-06 Identities = 126/608 (20%), Positives = 216/608 (35%), Gaps = 104/608 (17%) Query: 2232 HIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQ 2291 H P V +S+ST+ ++ P + +++P T+ TS R P S Sbjct: 1757 HHPEV--TSTSTTSIT---PNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISS 1811 Query: 2292 IGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN--------KLS 2343 G + ++ + TPS P L + S + ++P + + P + Sbjct: 1812 TGPVTATSFQTTTTYPTPSHP-HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIH 1870 Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ 2403 +P + P + K++GS ++T+P T + S P S S +K Sbjct: 1871 SMPTGTIPPPTTIKATGS---THTAP----------PMTPTTSGTSQSPSSFSTAKTSTS 1917 Query: 2404 MNNGNGANKKVELSRMSSTKSSGSESDRSER-PVLVRQSTFIKEAPSPTLRRKLEESASF 2462 + + E++ S+T + + R PV S P+P +S Sbjct: 1918 LPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP 1977 Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 S S+ P + T Q T +PS P +L TH +PP + + P Sbjct: 1978 FS---STGPMTATSFQTTTTYPTPSHPQTTLPTH----------VPPFSTSLV-----TP 2019 Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582 + I +H++ + I HS + ++P +T + TGS+ + + Sbjct: 2020 STHTVIITTHTQMATSASI---------HSTPTGTVPPPTTLKATGSTHTAPPMTV---- 2066 Query: 2583 KAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKT 2642 + SGT Q+ + +A + I + + P NS+S+ SS T Sbjct: 2067 -----------TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT------ 2109 Query: 2643 LIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV--SEKANPNIKDSKDN 2700 Q+ S T V N S SP+ + P + S S ++P Sbjct: 2110 ---QLPHLSSATTPV------STTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG 2160 Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760 + V S P+ + L + +S + P P P S ++I Sbjct: 2161 TSSSFV---SAPVHSTTLSSGSHSSLSTH-PTTASVSASP----LFPSSPAASTTIRATL 2212 Query: 2761 PFSSSSSSKHSS--PSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDS 2818 P + SS S+ P TV +P+P A ST A PS T + +T S Sbjct: 2213 PHTISSPFTLSALLPISTVTV-------SPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265 Query: 2819 KTDSTESS 2826 +T S Sbjct: 2266 SQSTTSRS 2273 Score = 48.1 bits (113), Expect = 1e-04 Identities = 148/779 (18%), Positives = 270/779 (34%), Gaps = 105/779 (13%) Query: 2099 FDWKAIQEGANSIVSSLHQAAAAACLSRQASSDS-DSILSLKSGISLGSPFHLTP----- 2152 F + +++++ H A + + A + + +LK+ S + +TP Sbjct: 1450 FSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGT 1509 Query: 2153 DQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQ 2212 Q F++NK P L ST + + + I ++ T +NS S + Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR-TPVAHTNSATSSR 1568 Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT-PASKSPSEGQTATTSP 2271 P + P P S +T+ P T P P T S Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628 Query: 2272 RGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP 2331 ++++ A S G+ P+ + ST + P L+ S +S++ Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMT-LTTSGTSQALSSLNT 1687 Query: 2332 GRNGISPPNKLSQLPRTSSPSTASTK------SSGSGKMSYTSPGRQMSQQNLTK---QT 2382 + S + S + ST++T S+G+ M+ T+ G S+ + + T Sbjct: 1688 AKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747 Query: 2383 GLSKNASSIPRSESASKGLNQMN-NGNGANKKVELSRMSSTKSS-------------GSE 2428 L + SS E S + N + ++ +S SS G+ Sbjct: 1748 SLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTT 1807 Query: 2429 SDRSERPVLVRQSTFIKEAPSP----TLRRKLEESASFESLSPSSRPAS-PTRSQAQTPV 2483 S PV P+P T S S ++PS+ PT +Q T Sbjct: 1808 PISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSA 1867 Query: 2484 LSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINR 2543 S+P ++ ++++A G P ++PT P+ + S +++ + LP + Sbjct: 1868 SIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS-----SFSTAKTSTSLPYHT 1922 Query: 2544 SGTWKREHSKHSSS--LPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601 S T E + S++ P+ ++ TG+ + + +S SS + + H Sbjct: 1923 SSTHHPEVTPTSTTNITPKHTS---TGTRTPVAHTTSASSSRLPTPFTTH---------- 1969 Query: 2602 KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRI 2661 SP +S S+G +T P+ +T Sbjct: 1970 -------------------SPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTT------ 2004 Query: 2662 EDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR 2721 PT + PP S+ + + + Q + S P TV Sbjct: 2005 ------------LPT-HVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTT 2051 Query: 2722 LNSFIQVD-APDQKGTEIKPGQNNPVPVSETNESSIVERTPF--SSSSSSKHSSPSGT-- 2776 L + AP T Q + + T SS + + + +SSS SSP T Sbjct: 2052 LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQL 2111 Query: 2777 --VAARVTPFNYNPSPRKSSADSTSARPSQIPT--PVNNNTKKRDSKTDSTESSGTQSP 2831 +++ TP + S + S SA PS + + P ++++ + S + T SS +P Sbjct: 2112 PHLSSATTPVSTTNQLSSSFSPSPSA-PSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169 Score = 33.9 bits (76), Expect = 2.4 Identities = 75/344 (21%), Positives = 118/344 (34%), Gaps = 37/344 (10%) Query: 2135 ILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKV 2194 I++ + ++ + H TP P T+ K T+ T Sbjct: 2025 IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATAS 2084 Query: 2195 YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLK 2254 + + + S P+ +P +S T + +SS S SP + Sbjct: 2085 SSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144 Query: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314 P+S S SP+ + PSV + S V+ SS + S + +T S A Sbjct: 2145 VPSSHS---------SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA- 2194 Query: 2315 QPL--SRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372 PL S P S + P + IS P LS L S+ + + T SS + P Sbjct: 2195 SPLFPSSPAASTTIRATLP--HTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPS-- 2250 Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432 T +T S + + S+S + + +V S S S + S Sbjct: 2251 ------TPRTTASTHTAPAFSSQSTT------SRSTSLTTRVPTSGFVSLTSGVTGIPTS 2298 Query: 2433 ERPVLVRQSTFIKEAPSPTL---RRKLEESASFESLSPSSRPAS 2473 PV + P PTL R L S + +P+S P S Sbjct: 2299 --PV----TNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVS 2336 >gi|50083281 KIAA1853 protein [Homo sapiens] Length = 611 Score = 65.1 bits (157), Expect = 1e-09 Identities = 122/516 (23%), Positives = 195/516 (37%), Gaps = 78/516 (15%) Query: 2189 KGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSK 2248 +G KK KS + RS+S +K+ + + R R+ + SS+SP SK Sbjct: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSF----SKKRRHSSSSPKSK 162 Query: 2249 KGPPLK-TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDS 2307 + + S+S R S SE P + ++ G S + +S R S Sbjct: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHS 222 Query: 2308 ----------TPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQL-PRTSSPSTAST 2356 +P + +P S+P+Q G S R I+ + L +T+SP T S Sbjct: 223 RRCSKTLCKDSPEAQSSRPPSQPLQMLGYLS---ARGVITGSGSAADLFTKTASPLTTSR 279 Query: 2357 KSS---------GSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNG 2407 S S + TS R Q+ + GLSK+ S + S N Sbjct: 280 GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSREL--NSGNTSDSGNSFTTS 337 Query: 2408 NGANKKVELSRMSSTKSSGSESDRSERPVL----VRQSTFIKEAPSPTLRRKLEESASFE 2463 + NK L +S T S G ES + P L V++S+ + + + S+S+ Sbjct: 338 SPQNKGAMLENLSPT-SRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYA 396 Query: 2464 SL---SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSP----TIE 2516 S S SSR +P S T S S S S S + ++ PP+ S + Sbjct: 397 STRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS 456 Query: 2517 YNDGRPAKRHDIA------------------RSHS-------ESPSRLPINRSGT----- 2546 Y+ P++ D RS+S +SPS L R + Sbjct: 457 YSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRP 516 Query: 2547 --WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKEN 2604 + R S SL S+W SSSS ++S S +++S S + T S + Sbjct: 517 IPYYRPSPSSSGSLSSTSSWY--SSSSS--RSASRSYSRSRSRSRSRRRSRTRTSSSSSS 572 Query: 2605 QVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640 + + G+ + + S + S SQ+ S + + S Sbjct: 573 RSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608 Score = 48.1 bits (113), Expect = 1e-04 Identities = 72/323 (22%), Positives = 121/323 (37%), Gaps = 28/323 (8%) Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSS 2242 S S G+ +++ + S + S Q K + N+ SRGR G ++ Sbjct: 311 SPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRES---RGFQSPCLE 367 Query: 2243 TSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRS 2302 + V KK + + A SP +G + ++S + S S SP R + + S S Sbjct: 368 CAEV-KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK 426 Query: 2303 GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSG 2362 S +PS ++ P R+ SP + SP + + + Sbjct: 427 RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRR 486 Query: 2363 KMSYT--SPGRQMSQQNLTKQTGLSKNASSIP---RSESASKGLNQMNNGNGANKKVELS 2417 + SY+ R+ S +L + S IP S S+S L+ ++ ++ S Sbjct: 487 RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS 546 Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRS 2477 R S S S S R R + S+S S SP SR S +RS Sbjct: 547 RSYSRSRSRSRSRRRS-------------------RTRTSSSSSSRSPSPGSRSRSRSRS 587 Query: 2478 QAQTPVLSPSLPDMSLSTHSSVQ 2500 ++++ S S S ++SS + Sbjct: 588 RSRSRSRSQSRSYSSADSYSSTR 610 Score = 40.4 bits (93), Expect = 0.025 Identities = 120/600 (20%), Positives = 224/600 (37%), Gaps = 79/600 (13%) Query: 2256 PASKSPSE--GQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTP--SR 2311 PA PSE GQ T P G + + T + G+++ S S +D TP S Sbjct: 54 PAQDGPSEKLGQHLATEPLGTNSWERDK-------TCRELGATRGHSASHDKDLTPPPSS 106 Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPR-------------TSSPSTASTKS 2358 ++ + + R S S + + K S +SSP + Sbjct: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE 166 Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRS-ESASKGLNQMNNGNGANKKVELS 2417 K S + P R+ + + S+++ S P S ES +G + +++ Sbjct: 167 KRHKKQSRSRP-RKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQK--SRRRHSR 223 Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL-SPSSRPASPTR 2476 R S T S +S RP S ++ + R + S S L + ++ P + +R Sbjct: 224 RCSKTLCKDSPEAQSSRP----PSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279 Query: 2477 SQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN--LSPTIEYNDGRPAKR-HDIARSHS 2533 ++Q + SS ++ G K P+ LS + E N G + + S Sbjct: 280 GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSP 339 Query: 2534 ESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVN 2593 ++ + N S T + S+ S P + SS + S + S K S + + Sbjct: 340 QNKGAMLENLSPTSRGRESRGFQS-PCLEC-AEVKKSSLVPSTARSSPMKGCSRSSSYAS 397 Query: 2594 SISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653 + S + S+ SP S + + +E ++ Y +P+ S Sbjct: 398 TRSSSHSSR------------------SPNPRASPRYTQSRSTSSEKRS--YSRSPSYSS 437 Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713 P + RS RSP+ + K + ++ + + PM Sbjct: 438 KSGK----RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPM 493 Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPV---SETNESSIVERTPFSSSSSSKH 2770 R + R +S ++A I + P+P S ++ S+ + + SSSSS+ Sbjct: 494 R----KRRRDSPSHLEA-----RRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRS 544 Query: 2771 SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830 +S S + + + + S R+S ++S+ S+ P+P + + + S++ S S ++S Sbjct: 545 ASRSYSRSR-----SRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599 Score = 35.8 bits (81), Expect = 0.62 Identities = 137/618 (22%), Positives = 208/618 (33%), Gaps = 127/618 (20%) Query: 1767 GKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDK 1826 GKKKK S K +++ Y K K++ +R S +K + + SK ++K Sbjct: 108 GKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEK 167 Query: 1827 LPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKE 1886 + R R + HH P SR+ S S + R E +K++ Sbjct: 168 RHKKQSRSRPRKSHRHRHHRCP--------SRSQSSESRPSSCESRHRGRSPEEGQKSRR 219 Query: 1887 NKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAA 1946 H+ S + +A + +P + QP +L S + I G+A Sbjct: 220 R---------HSRRCSKTLCKDSPEAQSSRPPS--QPLQMLGYLS----ARGVITGSGSA 264 Query: 1947 TDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASG 2006 D F +P+ S S S N+ + P +T S+G+ K SG Sbjct: 265 ADL----FTKTASPLTTSRGRSQEYDS-----GNDTSSPPSTQTSSARSRGQ-EKGSPSG 314 Query: 2007 YAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPR 2066 KS + S NS +S SP+ Sbjct: 315 GLSKSRELNSGNTSDSGNSFTTS----------------------------------SPQ 340 Query: 2067 NMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQ----EGANSIVSSLHQAAAAA 2122 N G +L LSP S + + Q E A SSL + A + Sbjct: 341 NKGAML-----------------ENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383 Query: 2123 CLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE 2182 + S S + S S SP PR + S+ + Sbjct: 384 SPMKGCSRSSSYASTRSSSHSSRSP------------NPRASPRYTQSRSTSSEKRSYSR 431 Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEIS---GQMKQPLQANMPSISRGRTMIHIPGVRNS 2239 S S K GK+ S + RS S + + P + S R R R Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER-----ARRR 486 Query: 2240 SSSTSPVSKKGPPLKTPASKSPS--EGQTATTSPRGA----KPSVKSELSPVARQTSQIG 2293 S SP+ K+ SPS E + T++ + +PS S S + + Sbjct: 487 RRSYSPMRKR-------RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSS 539 Query: 2294 GSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPST 2353 SS++ SRS SR + SR ++ +R S S SPG S S R+ S S Sbjct: 540 SSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRS---RSRSRSQ 596 Query: 2354 ASTKSSGSGKMSYTSPGR 2371 + + SS SY+S R Sbjct: 597 SRSYSSAD---SYSSTRR 611 Score = 35.0 bits (79), Expect = 1.1 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 32/193 (16%) Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPS------------------------SN 1224 SS+K+S+S S S S +S K S SS + +PS Sbjct: 423 SSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER 482 Query: 1225 AKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAE 1284 A+R+ + + + R P +++S + I Y +P SS SS S+ Sbjct: 483 ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYY--RPSPSSSGSLSSTSSWYSSS 540 Query: 1285 DEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKS-SRLQGSSLS 1343 +++ + S + + + TR++ S P+ R++S SR + S S Sbjct: 541 SSRSASRSYSRSRSR-----SRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595 Query: 1344 SESARHKAVEFSS 1356 + A +SS Sbjct: 596 QSRSYSSADSYSS 608 Score = 34.7 bits (78), Expect = 1.4 Identities = 54/216 (25%), Positives = 82/216 (37%), Gaps = 51/216 (23%) Query: 810 RSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATE- 868 RS +++GN T P T SS+ SRG +E+G G + E Sbjct: 281 RSQEYDSGNDTSSPPSTQT----SSARSRG--------------QEKGSPSGGLSKSREL 322 Query: 869 NPGTSSKRGLQISTTAAQIAKVM-EEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSA 927 N G +S G +T++ Q M E +S +E R S L C ++++L S+A Sbjct: 323 NSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC-LECAEVKKSSLVPSTA 381 Query: 928 AHT------HSNTYNFTKSENSNRTCSMPYAKLEY--KRSSNDSLNSVSSSDGYG-KRGQ 978 + S++Y T+S + + P A Y RS++ S S S Y K G+ Sbjct: 382 RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGK 441 Query: 979 MKPSIES---------------------YSEDDESK 993 P S YSE D + Sbjct: 442 RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ 477 Score = 32.7 bits (73), Expect = 5.2 Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 9/110 (8%) Query: 1146 RYSEEE-QHEEEERPTNYSIKYNE-EKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSG 1203 +YSE++ Q E ER Y+ KR D P + T + S SSSG Sbjct: 469 KYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528 Query: 1204 QSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSS 1253 S T SSS + S S ++ S ++SRS + + T SS Sbjct: 529 SLSSTSSWYSSSSSRSASRSYSR-------SRSRSRSRRRSRTRTSSSSS 571 Score = 32.3 bits (72), Expect = 6.9 Identities = 116/588 (19%), Positives = 198/588 (33%), Gaps = 107/588 (18%) Query: 2313 AQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372 A++PL R P N + P ++G P KL Q T T S + Sbjct: 38 ARKPLPRT--EPQNNPVVPAQDG--PSEKLGQHLATEPLGTNSWE--------------- 78 Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432 + ++ G ++ S+ S K L + G KK + +R +SS S Sbjct: 79 --RDKTCRELGATRGHSA-----SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSY----S 127 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT---PVLS---- 2485 PV ++ K + RR + S SP S+ R + Q+ P S Sbjct: 128 PSPVKKKKK---KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHR 184 Query: 2486 ----PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR--HDIARSHSESPSRL 2539 PS S S SS ++ + P + + R +K D + S P Sbjct: 185 HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244 Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTK 2599 P+ G + + S + +T S + S+ + S + Sbjct: 245 PLQMLG-YLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSAR 303 Query: 2600 QSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK-TLIYQMAPA-------- 2650 + + S G K +E + +TS + +S T+ ++K ++ ++P Sbjct: 304 SRGQEKGSPSGGLSKSRELN---SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG 360 Query: 2651 ----------VSKTEDVWVRIEDCPI-------------NNPRSGRSPTGNTPPVIDSVS 2687 V K+ V P+ ++ S RSP P Sbjct: 361 FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR 420 Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVP 2747 ++ S+ G S P R+ +R + +P + E P + Sbjct: 421 STSSEKRSYSRSPSYSSKSGKRSPPSRSS--RSRRSPSYSRYSPSR---ERDPKYSEKDS 475 Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPSGTVAARVT-------PFNYNPSPRK-------- 2792 E + R +S + SPS A R+T P+ Y PSP Sbjct: 476 QQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY-YRPSPSSSGSLSSTS 534 Query: 2793 ---SSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 SS+ S SA S + + +++R S+T ++ SS ++SP S S Sbjct: 535 SWYSSSSSRSASRSYSRSRSRSRSRRR-SRTRTSSSSSSRSPSPGSRS 581 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 62.4 bits (150), Expect = 6e-09 Identities = 131/615 (21%), Positives = 219/615 (35%), Gaps = 86/615 (13%) Query: 2253 LKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDST-PSR 2311 ++ P S +G T S + K E Q Q+ A + S+ S P R Sbjct: 1669 IEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPR 1728 Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR 2371 A++ + Q+ S+ P + PP+ + +P ++S +T + S P Sbjct: 1729 FAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAS 1788 Query: 2372 QMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR 2431 ++ L+ ++ +P S A + + A+ S + T SS S Sbjct: 1789 TLAPV-------LASTSAPVPASPLAPVSASASVS---ASVPASTSAAAITSSSAPASAP 1838 Query: 2432 SERPVLVRQST-----FIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSP 2486 + P+L ST + A P L L +++ +S PA+P + P +P Sbjct: 1839 APTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAP 1898 Query: 2487 SLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT 2546 + +S A P +P N PA A++H P + P+ + Sbjct: 1899 TASVPLAPASASAPA-------PAPTPVSAPNPAPPAPAQTQAQTHK--PVQNPLQTTSQ 1949 Query: 2547 WKREHSKHSSSLPRVSTWRRT---GSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKE 2603 ++ S LP T T S SI + S + A+ D K SK+ Sbjct: 1950 SSKQPPP-SIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKK 2008 Query: 2604 ------NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDV 2657 Q + W K T+ S S GA NG ES + Sbjct: 2009 LGPISPPQPPSVSAWNK------PLTSFGSAPSSEGAKNGQES---------------GL 2047 Query: 2658 WVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQ------------- 2704 + + P S GN V+ +SEK+ I + K+ + KQ Sbjct: 2048 EIGTDTIQFGAPASN----GNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPD 2103 Query: 2705 --NVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP-GQNNPVPVSETNESSIVERTP 2761 V N +G E L + DA +++P GQ P P + + + T Sbjct: 2104 LSPVENKEHKPGPIGKERSLKNRKVKDA-----QQVEPEGQEKPSPATVRSTDPV---TT 2155 Query: 2762 FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821 + + S+ S+ GT+ + V+ Y + ++S D T+ S T NNTK D+ + Sbjct: 2156 KETKAVSEMSTEIGTMIS-VSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVN 2214 Query: 2822 STESSGT-QSPKRHS 2835 + T PKR + Sbjct: 2215 NVPLPNTLPLPKRET 2229 Score = 46.6 bits (109), Expect = 4e-04 Identities = 198/993 (19%), Positives = 344/993 (34%), Gaps = 171/993 (17%) Query: 1103 RSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNY 1162 R + +E V +N +N + + D +K + S + S ++ +EE E + Sbjct: 1443 REAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASES 1502 Query: 1163 SIKYNE-----EKRHVDQPIDYSLKYATDI--PSSQ--KQSFSFSKSSSGQSSKTEHMSS 1213 S +NE EK++ D +K ++ P + K+SFS + Q+ + + Sbjct: 1503 S-DFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPP 1561 Query: 1214 SSENTSTPSSNAKRQNQLHPSSAQSRSG--QPQKAATCKVSSINQETIQTYCVEDTPICF 1271 S + N +R P S + G Q A T V IN + + E P Sbjct: 1562 KSGRNFSGPRNERRSG---PPSKSGKRGPFDDQPAGTTGVDLINGSS--AHHQEGVPNGT 1616 Query: 1272 SRCSSLSSLSSAEDEI--GCNQTTQEADSA------NTLQIAEIKEKIGTRSAEDPVSEV 1323 + +S S ++ G + ++ D+ N + I + EDP S + Sbjct: 1617 GQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNL 1676 Query: 1324 PAVSQHPRTKSSRLQGSSLSSESARHK---AVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380 S+ Q L E R K ++ + + K +QT K PP + ++ Sbjct: 1677 N--DDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPR-FAKKQ 1733 Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQ-------SEPCSGMVSGIISPSDLPDSPGQTMPP 1433 + S +S+ S + S S P ++ + + + P P T+ P Sbjct: 1734 ATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP-VPASTLAP 1792 Query: 1434 SRSKTPPPPPQT--------AQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDA 1485 + T P P + A VP + + A S P A + P + Sbjct: 1793 VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPAS 1852 Query: 1486 DTLL----------HFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGN 1535 T+L A+ S P +SS +A + P I +P + + Sbjct: 1853 VTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAP 1912 Query: 1536 ETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPA 1595 N A+ + K + + P Sbjct: 1913 APAPTPVSAPNPAPPAPAQTQAQTHKPV----------------------------QNPL 1944 Query: 1596 QT---ASKLPPPVARKPS-QLP--VYKLLPSQNRLQPQKHVSFTP--GDDMPRVYCVEGT 1647 QT +SK PPP R PS Q P + ++ PQ H + T D+ V Sbjct: 1945 QTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNK-----VAPP 1999 Query: 1648 PINFSTATSLSDLTIESPPNELA------------AGEGVRGGAQSGEFEKRDTI----P 1691 + + L ++ PP+ A + EG + G +SG DTI P Sbjct: 2000 AVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAP 2059 Query: 1692 TEGRSTDEAQG--GKTSSVTIPELDDNKAEE---GDILAECINSAMP-KGKSHKPFRVKK 1745 + +E + S+ IPE + + ++ G I A+ + P + K HKP + K Sbjct: 2060 ASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGK 2119 Query: 1746 IMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP---QNTEYRTRVRKNADSKNNLNAE 1802 S N+ D ++ +P KP P ++T+ T A S+ + Sbjct: 2120 ----------ERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIG 2169 Query: 1803 RVFSDNKDSKKQNLKNNSKVF---NDKLPN----NEDRVRGSFAFDSPHHYTPIEGTPYC 1855 + S + N K + + + LPN N ++ + + P T Sbjct: 2170 TMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRET 2229 Query: 1856 FSRNDSLSSLDFDDDDVDLSREKAELRKAKEN----KESEAKVTSH--------TELTSN 1903 ++ SL+S+ + E A RKA EN +E + VTS + S Sbjct: 2230 IQQSSSLTSVPPTTFSLTFKMESA--RKAWENSPNVREKGSPVTSTAPPIATGVSSSASG 2287 Query: 1904 QQSAN----KTQAIAKQPINRGQPKPILQKQSTFPQSS--------KDIPDRGAATDEKL 1951 +AN + ++ + P+ P L T+ SS D P+ ++L Sbjct: 2288 PSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQL 2347 Query: 1952 QNFAIENTPVCFSHNSSLSSL-SDIDQENNNKE 1983 Q ++ + SH S LS + S I Q+ N + Sbjct: 2348 QTSSLPSA----SHFSQLSCMPSLIAQQQQNPQ 2376 Score = 42.0 bits (97), Expect = 0.009 Identities = 55/275 (20%), Positives = 104/275 (37%), Gaps = 39/275 (14%) Query: 1397 ESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSR---SKTPPPPPQTAQT----- 1448 E++ V + S + S + +P G + R S PPPP AQ Sbjct: 362 ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPD 421 Query: 1449 KREVPKNKAPTAEKRESGPK----------QAAVNAAVQRVQVLPDADTLLHFATESTPD 1498 ++ VP P K++ + Q+ ++AAV+R + + + Sbjct: 422 RQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA-- 479 Query: 1499 GFSCSSSLSALSLDEPFIQKDV---ELRIMPPVQENDNGNETESEQPKESNENQEKEAEK 1555 +C+ L L ++K E+R +E + E E EQ +E + +EK+ E+ Sbjct: 480 --ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRER 537 Query: 1556 TIDSEKDLLDDSD-------------DDDIEILEECIISAMPTKSSRKAKKPAQTASKLP 1602 + EK+L + + + ++E +E K K + + KL Sbjct: 538 QQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLE 597 Query: 1603 PPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGD 1636 + R+P+ P+ + S+N ++ FT D Sbjct: 598 EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQD 632 Score = 35.0 bits (79), Expect = 1.1 Identities = 90/448 (20%), Positives = 170/448 (37%), Gaps = 81/448 (18%) Query: 2244 SPVSKKGPPLKTPASKSPSEGQ-TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRS 2302 S ++ P PA+ SP+ TA T P A P+ L+P + + AP+ Sbjct: 1866 SALASTSAPTPAPAASSPAAPVITAPTIPASA-PTASVPLAPASASAP-----APAPTPV 1919 Query: 2303 GSRDSTPSRPAQ------QPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAST 2356 + + P PAQ +P+ P+Q+ ++S P PP+ +LP +P+ Sbjct: 1920 SAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQP------PPS--IRLPSAQTPNGTDY 1971 Query: 2357 KSSGSGKMSYTSPGRQMSQ------------QNLTKQTGLSK---------------NAS 2389 +SG + S G ++ +++K+ G + Sbjct: 1972 VASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFG 2031 Query: 2390 SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449 S P SE A G +G + + + S+G+E++ PVL +S + P Sbjct: 2032 SAPSSEGAKNG-----QESGLEIGTDTIQFGAPASNGNENE--VVPVLSEKSA--DKIPE 2082 Query: 2450 PTLRRKLEESASFESLSPSSRP-ASPTRSQAQTP---VLSPSLPDMSLSTHSSVQAGGWR 2505 P +R+ + A + P SP ++ P SL + + V+ G Sbjct: 2083 PKEQRQKQPRAG--PIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQE 2140 Query: 2506 KLPPNLSPTIEYNDGRPAKR-HDIARSHSESPSRLPINRS--GTWKRE----HSKHSSSL 2558 K P T+ D K ++ +E + + ++ + GT +E ++ SSSL Sbjct: 2141 KPSP---ATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSL 2197 Query: 2559 PRVSTWRRTGSSSSILS--ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIK 2616 P T ++++ + K E + +S++ + + + RK Sbjct: 2198 PNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAW 2257 Query: 2617 EN------EFSPTNSTSQTVSSGATNGA 2638 EN + SP ST+ +++G ++ A Sbjct: 2258 ENSPNVREKGSPVTSTAPPIATGVSSSA 2285 Score = 32.0 bits (71), Expect = 8.9 Identities = 61/339 (17%), Positives = 118/339 (34%), Gaps = 22/339 (6%) Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740 S + E+ P E S D QG K S E ++NK E ++ +S +P S Sbjct: 335 SDDDEQGSNSPKENNSED--QGSKAS-----ENNENKKETDEVSNTKSSSQIPAQPSVAK 387 Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTS----PVKPIPQNTEYRT-------RV 1789 K Q+ SS P +L ++ P P +P P ++ + + Sbjct: 388 VPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQ 447 Query: 1790 RKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPI 1849 R+ S+ + ER ++ +++ + +KL ++++ SP Sbjct: 448 RRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER 507 Query: 1850 EGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQ-QSAN 1908 E R + + + REK R+ ++ KE E + E+ + Q Sbjct: 508 EREK---EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564 Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSS 1968 K K+ Q +K+ + + + ++ + L+ + + Sbjct: 565 KELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEE 624 Query: 1969 LSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGY 2007 + D + KE P+ P+S +P SGY Sbjct: 625 EPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGY 663 >gi|89026265 PREDICTED: mucin 12 [Homo sapiens] Length = 978 Score = 62.0 bits (149), Expect = 8e-09 Identities = 140/659 (21%), Positives = 234/659 (35%), Gaps = 76/659 (11%) Query: 2221 MPSISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSV 2278 M IS G T +PG S++T+ +S+K +P S + +TTS ++ S Sbjct: 1 MSPISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 56 Query: 2279 KSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI-- 2336 S P + T+ GS+ P S ++ S P + S +S+ P Sbjct: 57 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 116 Query: 2337 SPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE- 2395 P + + L ++ ++ ++S S SP +S T + G S S P S+ Sbjct: 117 GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 176 Query: 2396 ---------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD---------------- 2430 SA L+ ++G+ ++ SST SE Sbjct: 177 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 236 Query: 2431 -RSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPS 2487 RS LV +ST +P T ES++ S SR +S T + + P + + Sbjct: 237 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 296 Query: 2488 LPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSG-- 2545 L + S HSS + P S T H ++ +P SG Sbjct: 297 LVEEPTSYHSSPGSIATTHFPE--SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 354 Query: 2546 ----TWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601 T+ ++L +T + S+IL +SS S ++ S +SISG S Sbjct: 355 AESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTS 414 Query: 2602 KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRI 2661 +Q + T F + +TS T ++ + ++P S T + + Sbjct: 415 LYSQAESTHT------TAFPASTTTSGLSQESTTFHSKPGSTETTLSPG-SITTSSFAQE 467 Query: 2662 EDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR 2721 P + P S S + +SE++ GS N Sbjct: 468 FTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSP-----------GSTETTAFSHSNT 516 Query: 2722 LNSFIQVDAPDQKGTEIKPGQNNPV-PVSETNESSIVERTPFSSSSSSKHSSP------S 2774 ++ Q P PG + V P + T E T F SSS + ++P + Sbjct: 517 MSIHSQQSTPFPD----SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTA 572 Query: 2775 GTVAARVTPFNYNPSPRKSSADSTSARPSQI--PTPVNNNTKKRDSKTDSTESSGTQSP 2831 + T F +PSP ++ S+ S + + + + S STES T +P Sbjct: 573 SDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 631 Score = 33.5 bits (75), Expect = 3.1 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++SG+S S+T H S++ +S PS+ + + P+ Sbjct: 245 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 302 Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278 S S G P+ + T + S+ + + T + P F+ ++ Sbjct: 303 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 362 Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338 S S E + TT + +T+ + +RS + +S S + + L Sbjct: 363 SPGSMETTLASTTTTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 416 Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396 + S+ + A +SG S + P S ET L T+ S F Sbjct: 417 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 470 Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430 S+ ++ P S V G+ S SPG T Sbjct: 471 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 506 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 61.6 bits (148), Expect = 1e-08 Identities = 248/1342 (18%), Positives = 463/1342 (34%), Gaps = 227/1342 (16%) Query: 1202 SGQSSKTEHMSSSSENTSTPSSNAKRQNQ-LHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260 +G S +H SS+ + + P+S NQ P RS P + T S ++ I Sbjct: 100 TGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHI- 158 Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320 TP + + +I C ++T + + +K G R E + Sbjct: 159 ------TP-------------APKSKINCRKSTTGKST-----VTRKSDKTG-RPLEKSM 193 Query: 1321 S--EVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378 S + + S H T S G+S + K+ F + SK+ +T +P E Sbjct: 194 STLDKTSTSSHKTTTSFHNSGNS----QTKQKSTSFPEKITAASKTTYKTTGTPEESEKT 249 Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438 E SR T S D +++ + ++ + + + P+ + G+T + + T Sbjct: 250 ED----SRTTVAS--DKLLTKTTKNIQETISANELTQSLAEPT---EHGGRT--ANENNT 298 Query: 1439 PPPPPQTAQTKREVPKNKA-PTAEKRESGPKQAAVNAA------VQRVQVLPDADTLLHF 1491 P P T +R +N AE E+ + A N A + ++ + +T L F Sbjct: 299 PSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTL-F 357 Query: 1492 ATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETES-EQPKESNENQE 1550 E T G ++ + S EP + N N T S +P E E Sbjct: 358 PAEPTEHGERTANENTTPSPAEP----------TEHGERTANENTTPSPAEPTEHGERTP 407 Query: 1551 KEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPS 1610 +KT S + + + + A PT++ + T S P R+ + Sbjct: 408 FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467 Query: 1611 ---QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPN 1667 + + + P++NR + + TP P N T +S ++ T Sbjct: 468 ANEKTTLSPVEPTENR-ETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 526 Query: 1668 ELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAEC 1727 LA A+ PTE R + S E D + Sbjct: 527 PLANENTTPSPAE----------PTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS 576 Query: 1728 INSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRT 1787 + G+ PF +K ++SS+ P +++ ++ P + P E Sbjct: 577 LAEPTENGQ-RTPFANEK-------TTSSSAEPTEHE----ERTPLANENTTPSPAE--- 621 Query: 1788 RVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYT 1847 +N + N N + ++++ + +F + N +R SP T Sbjct: 622 -PTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPT 680 Query: 1848 PI-EGTPYCFSRNDSLSSLDFDDDD-VDLSREKAELRKAKENKESEAKVTSHTELTSNQQ 1905 + TP+ + S S+ + + L+ E L S A+ T + E T+N+ Sbjct: 681 ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTL--------SPAEPTENRERTANE- 731 Query: 1906 SANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSH 1965 KT +P + + + + P + DR +EK TP Sbjct: 732 ---KTTPFPAEP-TENRERTANENTTPSPAQPTENGDRTPLANEK-------TTP----- 775 Query: 1966 NSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNS 2025 + + N + P + S EP++ H E TP+ + Sbjct: 776 --------SLAEPTENGKRTPFANEKTTSSSAEPTE-----------HAERTPLANENTT 816 Query: 2026 SLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQR 2085 S + ++ + E ++ P + +R NEK +P Sbjct: 817 SSPAEPTENRERTANE-KTTQFPAEPTENRESTANEKTTPFP------------------ 857 Query: 2086 PDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLG 2145 + +EN +W A + LS ++ + + L + + Sbjct: 858 -------AEPTENREWTANEN---------------TTLSPAEPTEHEEMTPLANEKTTL 895 Query: 2146 SPFHLTPDQEEKPFTSNK-GPRILKP---GEKSTLETK-KIESESKGIKGGKKVYKSLIT 2200 SP T + E PFT+ K P +P GE++ L + S ++ + G+++ T Sbjct: 896 SPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKAT 955 Query: 2201 ---GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPV------SKKGP 2251 K + E + + P+ + RT + N +++TSP + Sbjct: 956 PSPAKPTEHGETTVNEDTTPSSAEPTENGERTPL-----ANENTTTSPTESTEHGERTAN 1010 Query: 2252 PLKTPASKSPSEGQTAT------TSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSR 2305 TP+ P+E T T P AKP+ E++P A + + S P+ G + Sbjct: 1011 EKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTT--PSPVKPTEHGEK 1068 Query: 2306 DSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMS 2365 + + P + + + + + S RT+SP+ T S+ S Sbjct: 1069 TTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAE---S 1125 Query: 2366 YTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425 R S +T ++ R+ A + + Q+ + + + +T ++ Sbjct: 1126 TEHRDRATSANVITPAP--AEPIKHAKRTTLAHEKMTQVTEKSTEHPE------KTTSTT 1177 Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL------SPSSRPASPTRSQA 2479 + E+P L + T + + + K E+ +L +P +P ++ A Sbjct: 1178 EKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAA 1237 Query: 2480 QTPVLSPSLP---DMSLSTHSS 2498 T + PS+ D SL+T SS Sbjct: 1238 VTKTIKPSVKVTGDKSLTTTSS 1259 Score = 51.6 bits (122), Expect = 1e-05 Identities = 111/598 (18%), Positives = 201/598 (33%), Gaps = 84/598 (14%) Query: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314 TP+ P+E + T + + V+ + + S P+ +G R + Sbjct: 454 TPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTT 513 Query: 2315 QPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMS 2374 + P + R ++ SP RT++ T + + + T + + Sbjct: 514 SSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKT 573 Query: 2375 QQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSER 2434 +L + T +N P AN+K +T SS ++ ER Sbjct: 574 TPSLAEPT---ENGQRTP----------------FANEK-------TTSSSAEPTEHEER 607 Query: 2435 PVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT----PVLSPSLPD 2490 L ++T PSP + E + E+ +PS PA PT ++ T L P+ P Sbjct: 608 TPLANENT----TPSPAEPTENRERTANENTTPS--PAGPTENREMTANEKTTLFPAEP- 660 Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKRE 2550 T + + + PT +R A + S S P Sbjct: 661 ----TENRERTANEKTTSSPAEPT------ENGQRTPFANEKTTSSSAEP---------- 700 Query: 2551 HSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKG 2610 ++H P + ++ LS + + + ++ +EK + +++E + Sbjct: 701 -TEHGERTP-------LANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENT 752 Query: 2611 TWRKIK--ENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINN 2668 T + EN + +T S A K + S + + E P+ N Sbjct: 753 TPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLAN 812 Query: 2669 PRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR-----LN 2723 + SP T + +EK + +N+ + + P ENR N Sbjct: 813 ENTTSSPAEPTENRERTANEKTTQFPAEPTENR-ESTANEKTTPFPAEPTENREWTANEN 871 Query: 2724 SFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF-------SSSSSSKHSSPSGT 2776 + + P + E+ P N +S + ERTPF SS+ ++H + Sbjct: 872 TTLSPAEPTEH-EEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPL 930 Query: 2777 VAARVTPFNYNPSPRKSSADSTSARPSQI-PTPVNNNTKKRDSKTDSTE--SSGTQSP 2831 TP P+ + A PS PT T D+ S E +G ++P Sbjct: 931 ANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTP 988 Score = 43.1 bits (100), Expect = 0.004 Identities = 192/1081 (17%), Positives = 371/1081 (34%), Gaps = 133/1081 (12%) Query: 977 GQMKPSIESYSEDDESK-FCSYGQY------PADLAHKIHSANHMDDNDGELDTPINYSL 1029 GQ P + +E E K C+ ++ P + I + D+++ + N S Sbjct: 68 GQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSN 127 Query: 1030 KYSDEQLNSGRQ-----SPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDD 1084 + D + + R S + ++ A KHI + R+S +T ++ T Sbjct: 128 QGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGR 187 Query: 1085 KHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYS 1144 ++ +S + +T N G +Q +S + T Y Sbjct: 188 P---------LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK 238 Query: 1145 ERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQ 1204 + EE + E+ T + S K T + +++ S ++ + Sbjct: 239 TTGTPEESEKTEDSRTTVA----------------SDKLLTKTTKNIQETISANELTQSL 282 Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCV 1264 + TEH ++ +TPS +N+ ++ ++ + P + + + N+ T + Sbjct: 283 AEPTEHGGRTANENNTPSPAEPTENR-ERTANENTTLSPAEPIENRERTANENT-APFPA 340 Query: 1265 EDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVP 1324 T + ++L AE +T E NT + G R+A + + P Sbjct: 341 GPTENREMTANENTTLFPAEPTEHGERTANE----NTTPSPAEPTEHGERTANENTTPSP 396 Query: 1325 A--VSQHPRTKSSRLQGSSLSSESARH--------------KAVEFSSGAKSPSKSGAQT 1368 A RT + + +S S+ES H A + ++ +++ + Sbjct: 397 AEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPS 456 Query: 1369 PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPG 1428 P P E+ +ET + T++S ++ E+R ++ ++ P SP++ P G Sbjct: 457 PAGPTEN--RETTA--NEKTTLSPVEPTENRETTANEKTTP---------SPAE-PTENG 502 Query: 1429 QTMPPSRSKTPPPPPQTAQTKREVP---KNKAPT-AEKRESGPKQAAVNAAVQRVQVLPD 1484 Q P + KT + + P +N P+ AE E+ + A + + Sbjct: 503 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 562 Query: 1485 ADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDN---GNETESEQ 1541 D ++TP + + PF + P + + NE + Sbjct: 563 GDRTPLANEKTTPS----LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPS 618 Query: 1542 PKESNENQEKEA-EKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASK 1600 P E EN+E+ A E T S ++ + E + + A PT++ + T+S Sbjct: 619 PAEPTENRERTANENTTPSPAGPTENREMTANE--KTTLFPAEPTENRERTANEKTTSSP 676 Query: 1601 LPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDL 1660 P + P + + +P +H TP E T ++ + T + Sbjct: 677 AEP--TENGQRTPFANEKTTSSSAEPTEHGERTP-------LANENTTLSPAEPTENRER 727 Query: 1661 TIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKT---SSVTIPELDDNK 1717 T A + E +T P+ + T+ G +T + T P L + Sbjct: 728 TANEKTTPFPAEPTENRERTANE----NTTPSPAQPTE--NGDRTPLANEKTTPSLAE-- 779 Query: 1718 AEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTS-PV 1776 E N + ++ + ++S + P +N+ +K T P Sbjct: 780 PTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPA 839 Query: 1777 KPI--------PQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLP 1828 +P + T + +N + N N ++ + ++ N K Sbjct: 840 EPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAE 899 Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888 E+ R F + TP P L++ + E E ++ Sbjct: 900 PTENGERTPFTNEKT---TPSSAEPTEHGERTPLAN-EITTPSRAEPTEHGERIANEKAT 955 Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPIL-QKQSTFPQSSKDIPDRGAAT 1947 S AK T H E T N+ T + +P G+ P+ + +T P S + +R A Sbjct: 956 PSPAKPTEHGETTVNED----TTPSSAEPTENGERTPLANENTTTSPTESTEHGERTA-- 1009 Query: 1948 DEKLQNFAIENTPVCFSHNSSLSSLSD--IDQENNNKENEPIKETEPPDSQGEPSKPQAS 2005 +EK E T H S ++ I E+E + + ++ P KP Sbjct: 1010 NEKTTPSPAEPT----EHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH 1065 Query: 2006 G 2006 G Sbjct: 1066 G 1066 Score = 37.7 bits (86), Expect = 0.16 Identities = 65/329 (19%), Positives = 122/329 (37%), Gaps = 37/329 (11%) Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581 PA + I S + +S R K S+L + ST ++S S +S++ Sbjct: 160 PAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTK 219 Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK 2641 +K+ S EK + T ++ GT + ++ E S T S + + T + Sbjct: 220 QKSTSFPEKITAASKTTYKTT-------GTPEESEKTEDSRTTVASDKLLTKTTKNIQET 272 Query: 2642 TLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQ 2701 ++ ++++ + R + NN S PT N + + + ++++ Sbjct: 273 ISANELTQSLAEPTEHGGRTAN--ENNTPSPAEPTENRERTANENTTLSPAEPIENRERT 330 Query: 2702 AKQNVGNGSVPMRTVGLENRL-----NSFIQVDAPDQKGTEIKPGQNNPVPVSET----- 2751 A +N + P ENR N+ + P + G P P T Sbjct: 331 ANEN----TAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGER 386 Query: 2752 --NESSIV---------ERTPFSSSSSSKHSSPSGTVAARVTPFNYN--PSPRKSSAD-S 2797 NE++ ERTPF++ ++ S+ S R N N PSP + + + Sbjct: 387 TANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRE 446 Query: 2798 TSARPSQIPTPVNNNTKKRDSKTDSTESS 2826 +A + P+P + + + T S Sbjct: 447 RTANENTTPSPAGPTENRETTANEKTTLS 475 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 60.8 bits (146), Expect = 2e-08 Identities = 139/656 (21%), Positives = 234/656 (35%), Gaps = 76/656 (11%) Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281 IS G T +PG S++T+ +S+K +P S + +TTS ++ S S Sbjct: 975 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1030 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339 P + T+ GS+ P S ++ S P + +S +S+ P P Sbjct: 1031 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPG 1090 Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395 + + L ++ ++ ++S S SP +S T + G S S P S+ Sbjct: 1091 STETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1150 Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432 SA L+ ++G+ ++ SST SE RS Sbjct: 1151 APPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARS 1210 Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490 LV +ST +P T ES++ S SR +S T + + P + +L + Sbjct: 1211 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1270 Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSG----- 2545 S HSS + P S T H ++ +P SG Sbjct: 1271 EPTSYHSSPGSIATTHFPE--SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES 1328 Query: 2546 -TWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKEN 2604 T+ ++L +T + S+IL +SS S ++ S +SISG S + Sbjct: 1329 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 1388 Query: 2605 QVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDC 2664 Q + T F + +TS T ++ + ++P S T + + Sbjct: 1389 QAESTHT------TAFPASTTTSGLSQESTTFHSKPGSTETTLSPG-SITTSSFAQEFTT 1441 Query: 2665 PINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS 2724 P + P S S + +SE++ GS N ++ Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSP-----------GSTETTAFSHSNTMSI 1490 Query: 2725 FIQVDAPDQKGTEIKPGQNNPV-PVSETNESSIVERTPFSSSSSSKHSSP------SGTV 2777 Q P PG + V P + T E T F SSS + ++P + + Sbjct: 1491 HSQQSTPFPD----SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 1546 Query: 2778 AARVTPFNYNPSPRKSSADSTSARPSQI--PTPVNNNTKKRDSKTDSTESSGTQSP 2831 T F +PSP ++ S+ S + + + + S STES T +P Sbjct: 1547 VGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 1602 Score = 50.1 bits (118), Expect = 3e-05 Identities = 126/620 (20%), Positives = 211/620 (34%), Gaps = 65/620 (10%) Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281 S R H+P SS S + P T + P +TT P ++ S S Sbjct: 562 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 617 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341 SP T+ GS+ A S + SRP + P + S P + Sbjct: 618 SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 674 Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392 ++ P T+ ST G ++ P + + T + SSIP Sbjct: 675 STRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 734 Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445 + S + GL ++ G+ + + +T G ES S + I Sbjct: 735 THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 790 Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505 APS T +EE S+ S SP S + + T S + S+++HSS A G Sbjct: 791 SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESIASHSSQDATGTI 844 Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLP--INRSGTWKREHSKHSSSLPRVST 2563 LP + ++ + + S S + LP G +R + HSS +T Sbjct: 845 VLPARSTNSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 900 Query: 2564 WRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPT 2623 ++SS +S S +S S T + + + P Sbjct: 901 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 960 Query: 2624 NSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVI 2683 ++T+ V T+ S + P + T + + ++PRS + Sbjct: 961 STTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEK-STTFYSSPRSPDTTLSPASTTS 1019 Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQN 2743 VSE++ + S+ GS M V E+ + +P T + P Sbjct: 1020 SGVSEESTTS--HSRPGSTHTTAFPGSTTMPGVSQESTASH----SSPGSTDTTLSP--- 1070 Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPS---PRKSSADSTSA 2800 T SS+ S++ HS P G+ + P N S + S++ Sbjct: 1071 -----RSTTASSL------GPESTTFHSGP-GSTETTLLPDNTTASGLLEASTPVHSSTG 1118 Query: 2801 RPSQIPTPVNNNTKKRDSKT 2820 P +P + T++ +S T Sbjct: 1119 SPRTTLSPAGSTTRQGESTT 1138 Score = 49.7 bits (117), Expect = 4e-05 Identities = 132/603 (21%), Positives = 216/603 (35%), Gaps = 93/603 (15%) Query: 2254 KTPASKSPSEGQTATTSPRGAKPSV------KSELSPVARQTSQIGGSSKAPS---RSGS 2304 ++ AS S + T P G+ PSV S +S + +T+ + GS+ P +S + Sbjct: 500 ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 559 Query: 2305 RDSTPSRPAQQPLSRPIQSPGRNSIS------PGRNGISPPNKLSQLPRTSSPSTASTKS 2358 S+P P L + S G + S PG + + +P S STAS S Sbjct: 560 FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619 Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASS-----IPRSESASKGLNQMN---NGNGA 2410 G + SPG + + T S +P + +AS GL + + + + Sbjct: 620 PGPTDTTL-SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS-GLLEASMPVHSSTR 677 Query: 2411 NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSR 2470 + LS ST G + P S + AP T +E S + SPSS Sbjct: 678 SPHTTLSPAGSTTRQGESTTFHSWP----SSNDTRPAPPTTTSAFVEPSTTSHG-SPSSI 732 Query: 2471 PASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY--NDGRPAKRHDI 2528 P + +++ T L + S + HSS P + T+ + +D + + Sbjct: 733 PTTHISARSTTS----GLVEESTTYHSS----------PGSTQTMHFPESDTTSGRGEES 778 Query: 2529 ARSHSESP---SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585 SHS + S P S + S HSS P + SS+ S ES Sbjct: 779 TTSHSSTTHTISSAPSTTSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESIASHS 836 Query: 2586 SEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIY 2645 S+D +I +S + + + T I S + T+ S T G ++ + Sbjct: 837 SQDA--TGTIVLPARSTNSVLLGESTTSPIS----SGSMETTALPGSTTTPGLSERSTTF 890 Query: 2646 QMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQN 2705 +P +P + SP T VSE++ + Sbjct: 891 HSSP-----------------RSPATTLSPASTTS---SGVSEESTTSHSRPGSTHTTAF 930 Query: 2706 VGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSS 2765 + + P GL +S +P T + P V E S P SS Sbjct: 931 PDSTTTP----GLSR--HSTTSHSSPGSTDTTLLPASTTTXLVGEPTTS------PISSG 978 Query: 2766 SSSKHSSPSGTVAARVT--PFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDST 2823 S+ + P T A ++ + SPR S D+T + S + V+ + S+ ST Sbjct: 979 STETTALPGSTTTAGLSEKSTTFYSSPR--SPDTTLSPASTTSSGVSEESTTSHSRPGST 1036 Query: 2824 ESS 2826 ++ Sbjct: 1037 HTT 1039 Score = 34.7 bits (78), Expect = 1.4 Identities = 85/384 (22%), Positives = 136/384 (35%), Gaps = 55/384 (14%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++S G+ S T H S++ +S PS+ + + P+ Sbjct: 747 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 804 Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282 S S G P + T S ++E+I ++ +D P + L ++ Sbjct: 805 SYHSSPGSTATTHFPDSSTT---SGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTT 861 Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336 + G +TT S T ++E + + PA VS+ T SR Sbjct: 862 SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 921 Query: 1337 --------LQGSSLSSESARHKAVEFSSGAKS-----PSKS-----GAQTPKSPPEHYVQ 1378 S+ + +RH SS + P+ + G T + Sbjct: 922 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTE 981 Query: 1379 ETPLMFSRCTSVSSLDS--FESRSIASSVQSEPCSGMVSGIISPSDLPDS-PGQTMPPS- 1434 T L S T+ S S F S + P S SG+ S S PG T + Sbjct: 982 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 1041 Query: 1435 -RSKTPPPPPQTAQTKREVPKNKAPTAEKRES-----GPKQAAVNAAVQRVQ--VLPDAD 1486 S T P Q + P + T R + GP+ ++ + +LPD Sbjct: 1042 PGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNT 1101 Query: 1487 TLLHFATESTPDGFSCSSSLSALS 1510 T STP S S + LS Sbjct: 1102 TASGLLEASTPVHSSTGSPRTTLS 1125 Score = 33.5 bits (75), Expect = 3.1 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234 ++ S Y + S+Q F S ++SG+S S+T H S++ +S PS+ + + P+ Sbjct: 1216 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 1273 Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278 S S G P+ + T + S+ + + T + P F+ ++ Sbjct: 1274 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 1333 Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338 S S E + TT + +T+ + +RS + +S S + + L Sbjct: 1334 SPGSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 1387 Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396 + S+ + A +SG S + P S ET L T+ S F Sbjct: 1388 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 1441 Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430 S+ ++ P S V G+ S SPG T Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 1477 >gi|149944526 additional sex combs like 3 [Homo sapiens] Length = 2248 Score = 60.8 bits (146), Expect = 2e-08 Identities = 236/1082 (21%), Positives = 369/1082 (34%), Gaps = 177/1082 (16%) Query: 1777 KPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRG 1836 K IP+ +E A+S N + E + +D+ + + N + + LP+ E ++ G Sbjct: 471 KTIPEFSE-------EAESLTNSHEEPQIAPPEDNLESCVMMNDVL--ETLPHIEVKIEG 521 Query: 1837 SFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTS 1896 I+ C S S SS+ D E+KESE V + Sbjct: 522 KSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDT--------------EHKESETAVET 567 Query: 1897 HTELTSNQQSANKTQ----AIAKQPINRGQPKPILQKQSTFPQSS----------KDIPD 1942 T S+ + Q IA + P+ L + + ++S +P Sbjct: 568 STPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPS 627 Query: 1943 RGA---ATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKEN---------EPIKET 1990 G +T E+ A T C S SS + +Q N+ EN PI T Sbjct: 628 PGGETQSTSEESCTPASLETTFC-SEVSSTENTDKYNQRNSTDENFHASLMSEISPIS-T 685 Query: 1991 EPPDSQGE-----PSKPQASGYAPKSFHVEDTPVC----FSRNSSLSSLSIDSEDDLLQE 2041 P S+ P +AS + E +P+ S SS+SS+ + SE + Sbjct: 686 SPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVS- 744 Query: 2042 CISSAMPKKKKPSRLKGDNEK--HSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENF 2099 S +P + P NE+ H R + E L+ Q+ +S P EN Sbjct: 745 --SLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSP-----QKDESSATAKPLGENL 797 Query: 2100 --DWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLT-PDQEE 2156 K + I+ S A A S + + S + KS + P+ + P+ Sbjct: 798 TSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELAS 857 Query: 2157 KPFTSNKGPRILKPGEKSTLETK---KIESESKGIKGGKKVYKSLITGKVRSNSEISGQM 2213 K +L+ EK L + + SE KG + L + K++ IS Sbjct: 858 TEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNE-----LPSAKLQDKQYISSVD 912 Query: 2214 KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRG 2273 K P SR +T H G S TS SK P K+P +E + + S R Sbjct: 913 KAPFSEG----SRNKT--HKQGSTQSRLETSHTSKSSEPSKSPDGIR-NESRDSEISKR- 964 Query: 2274 AKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333 K + + + ++I + S S +P Q P P P + +S Sbjct: 965 -KTAEQHSFGICKEKRARIEDDQSTRNISSS---SPPEKEQPPREEPRVPPLKIQLSK-- 1018 Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 I PP + P + S AST +S SG GR + L ++ A + Sbjct: 1019 --IGPPFIIKSQPVSKPESRASTSTSVSG-------GRNTGARTLADIKARAQQARA--- 1066 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLR 2453 Q A S +S S E ++ R IKE L Sbjct: 1067 ---------QREAAAAAAVAAAASIVSGAMGSPGEGGKT------RTLAHIKEQTKAKLF 1111 Query: 2454 RKLEESASFESLSPSSRPASPTRSQAQTPVLS-PSLPDMSLSTHSSVQAGGWRKLPPNLS 2512 K + A S +R P S+ P L S P+ + + V + PN Sbjct: 1112 AKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVII-----VNPN-- 1164 Query: 2513 PTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSS 2572 RS S + L R T + S + S LP +T SS Sbjct: 1165 ----------------CRSPSNKSAHL---RETTTVLQQSLNPSKLPETATDLSVHSSDE 1205 Query: 2573 ILSASSESSEKAKSEDEKHVNSIS--GTKQSKENQVSAKGTWRKIKENEF-SPTNSTSQT 2629 + S SEK S +S+ K S V + IKE+ F S + +S Sbjct: 1206 NIPV-SHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264 Query: 2630 VSSGATNGAESKTLIYQMAPAVSKTEDVWVR-----IEDCPINNPRSGRSPTGNTPPVID 2684 +S + N S I M + T+ + IE PI+ G S + + Sbjct: 1265 MSVDSANTTISACNI-SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQL 1323 Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744 +S + N+ ++ SVP ++G S V P P + Sbjct: 1324 LISSSSASNLVSTQYT---------SVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKI 1374 Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVT---------PFNYNPSPRKSSA 2795 +P SE + + T ++ S S + + ++ A T N SP K SA Sbjct: 1375 AIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSA 1434 Query: 2796 DS 2797 +S Sbjct: 1435 ES 1436 Score = 33.1 bits (74), Expect = 4.0 Identities = 52/268 (19%), Positives = 104/268 (38%), Gaps = 47/268 (17%) Query: 2569 SSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQ 2628 S+SSI + K+ S E+ ++ Q E+ +AK + + + +N+ Sbjct: 756 SNSSINERMAHQQRKSPSVSEEPLSP-----QKDESSATAKPLGENLTSQQKNLSNTPEP 810 Query: 2629 TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSE 2688 + S ++ +AP +ED+ + + ++ +S P S+ E Sbjct: 811 IIMSSSS-----------IAPEAFPSEDLHNKTL-----SQQTCKSHVDTEKPYPASIPE 854 Query: 2689 KANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPV 2748 A+ + K++ Q +P + L + + D KG E+ + + Sbjct: 855 LASTEMIKVKNHSVLQRTEKKVLP-------SPLELSVFSEGTDNKGNELPSAK-----L 902 Query: 2749 SETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTP 2808 + S V++ PFS S +K + G+ +R+ ++S S S+ PS+ P Sbjct: 903 QDKQYISSVDKAPFSEGSRNK-THKQGSTQSRL----------ETSHTSKSSEPSKSPDG 951 Query: 2809 VNNNTKKRD---SKTDSTESSGTQSPKR 2833 + N ++ + KT S G KR Sbjct: 952 IRNESRDSEISKRKTAEQHSFGICKEKR 979 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 59.3 bits (142), Expect = 5e-08 Identities = 275/1438 (19%), Positives = 488/1438 (33%), Gaps = 203/1438 (14%) Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183 +ED K T S+ S E EEEE + K N D P K Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125 Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243 + + K S ++G++ S ++ PS+N ++ + G Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185 Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303 K + + EDT SS+ DE E Sbjct: 186 AKPGMVSAGQADSSS------EDT-------------SSSSDETDVEVKASEKILQVRAA 226 Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPR-------TKSSRLQGSSLSSESARHKAVEFSS 1356 A K G + P + AV+ + ++SS + S E+ KA+ + Sbjct: 227 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 286 Query: 1357 GAKSPSKSGAQT---PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSE----- 1408 + S+ GA + +SP + P + + E S +SS +S+ Sbjct: 287 ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346 Query: 1409 PCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQT--AQTKREVPKNKAPTAEKRESG 1466 P SG +P + P + P PP +T A + +V K + + E Sbjct: 347 PAQAKPSGKAPQVRAASAPAKE-SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405 Query: 1467 PKQAAVNAAVQRVQVLP--------DADTL----LHFATESTPDGFSCSSSLSA------ 1508 AA+ QV P A T+ L P G ++ SA Sbjct: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465 Query: 1509 ----LSLDEPFIQKDVEL-RIMPPVQENDNGNETESEQPKESNENQ---------EKEAE 1554 S +E D E+ + P QE GN +++ + + +AE Sbjct: 466 EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 525 Query: 1555 KTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPV 1614 K +D+ + + SD D E +AM ++ A K QT + +K + Sbjct: 526 KPMDNSESSEESSDSADSEEAP----AAMTAAQAKPALKIPQTKA-----CPKKTNTTAS 576 Query: 1615 YKLLPSQNRLQ-PQKHVSFT-PGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAG 1672 K+ P + Q P+K + T P P V P S+++ SD E LA Sbjct: 577 AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD--SEEEKTGLAVT 634 Query: 1673 EGVRGGAQSGEFEKRDTIPTE---GRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECIN 1729 G G K ++P + G+ T GKT T+ ++ K E+ + E + Sbjct: 635 VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP-TVTQVKAEKQEDSESSEEESD 693 Query: 1730 SAMPKGKSHKPFRVKKIMDQVQ-----------QASASSSAPNKNQLDGKKKKPTSP--V 1776 S + + P +VK + + Q A + SAP K + K SP V Sbjct: 694 S---EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750 Query: 1777 KPIPQNTEYRTRVRKNADSKNNLN------AERVFSDNKDSKKQNLKNNSK-----VFND 1825 KP +N + T + + S ++ A+ +DS +++S+ + Sbjct: 751 KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 810 Query: 1826 KLPNNEDRVRGSFAFDSPHHYTPIEG-TPYCFSRNDSLSSLDFDDDDVDLSREKAELRKA 1884 K ++R + A P +P +G P + ++ DD S E+++ Sbjct: 811 KPSGKTHQIRAALA---PAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESD---- 863 Query: 1885 KENKESEAKVTSHTEL------TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSK 1938 + E+ A VTS + +S A Q P+ +ST SS Sbjct: 864 -SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSS 922 Query: 1939 DIPDRGAATDEKLQNFAIENTPVCF-SHNSSLSSLSDIDQENNNKENEPI---KETEPPD 1994 + D + I V + + ++ + + +++KE+ I K+ E P Sbjct: 923 ESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA 982 Query: 1995 SQGEPSKPQASGYAPKSFHV-------EDTPVCFSRNSSLSSLSIDSEDDLLQECISSAM 2047 +Q P + + V PV ++ SS +DS L A Sbjct: 983 TQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSS----GVDSAVGTL-----PAT 1033 Query: 2048 PKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEG 2107 + + KG N+ P+ + + + D DS S E+ + + Sbjct: 1034 SPQSTSVQAKGTNKLRKPK-LPEVQQATKAPESSD-DSEDSSDSSSGSEEDGEGPQGAKS 1091 Query: 2108 ANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKG-PR 2166 A+++V A S D +++ + G ++TP ++K P+ Sbjct: 1092 AHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG---YMTPGLTPANSQASKATPK 1148 Query: 2167 I-LKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSIS 2225 + P STL K + K + +++ K SG P ++ P Sbjct: 1149 LDSSPSVSSTLAAKDDPDGKQEAKPQQAA--GMLSPKTGGKEAASG--TTPQKSRKPK-- 1202 Query: 2226 RGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPV 2285 G N +ST + +E Q + + V +EL + Sbjct: 1203 --------KGAGNPQASTLALQSNITQCLLGQPWPLNEAQV-----QASVVKVLTEL--L 1247 Query: 2286 ARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQL 2345 ++ ++ ++K SR G QP +R +S + + G G Sbjct: 1248 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG---------- 1297 Query: 2346 PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTG---LSKNASSIPRSESASKGLN 2402 + SP ST S G K R + ++ ++ G L + E KG+ Sbjct: 1298 EASVSPEKTSTTSKGKAK-------RDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG 1350 Query: 2403 QMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 + G+ +N K + + S K + + ++ + ST E+PS ++K +++A Sbjct: 1351 TVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1408 Score = 50.8 bits (120), Expect = 2e-05 Identities = 153/868 (17%), Positives = 292/868 (33%), Gaps = 113/868 (13%) Query: 2045 SAMPKKKKPSRLKGDNEKHSPR---NMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDW 2101 S ++ + + K +PR +LG DL +K+ + ++E + Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142 Query: 2102 KAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQ-----EE 2156 + AN + + +A + S+++ S+ + + P ++ Q E+ Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202 Query: 2157 KPFTSNKGPRILKPGEKSTLETKKIESESKGIKG--------GKK--VYKSLITGKVRSN 2206 +S++ +K EK L+ + + +KG G GK V GK + Sbjct: 203 TSSSSDETDVEVKASEK-ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 261 Query: 2207 SEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQT 2266 SE S + + P+ + ++ +S TS V P K K + Sbjct: 262 SESSSEESSDSEEETPA---AKALLQA----KASGKTSQVGAASAPAKESPRKGAAPAPP 314 Query: 2267 ATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPG 2325 T P AK + + +AP+++ P R A P +SP Sbjct: 315 GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPR 371 Query: 2326 RNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGS----------------GKMSYTSP 2369 + + P Q+ + S +S++ S S GK P Sbjct: 372 KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 431 Query: 2370 GRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSES 2429 M L K G P + SA G + ++ + + + + S + Sbjct: 432 ASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 491 Query: 2430 DRSERPVLVRQSTFIKEAPSP----------TLRRKLEESASFESLSPSS----RPASPT 2475 ++S +L + T P + ++ S S E S S+ PA+ T Sbjct: 492 EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551 Query: 2476 RSQAQTPVLSPSLPDMSLSTHSSVQA--------------GGWRKLPPNLSPTIEYNDGR 2521 +QA+ + P T+++ A G P SP + R Sbjct: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611 Query: 2522 PAKRHDIARSHSESPSR-------LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSIL 2574 PA + + S ES S + + ++ + + ++S+P V G++ + Sbjct: 612 PA---EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLP 667 Query: 2575 SASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGA 2634 + + + K+E ++ S S+E S +K+ + + ++ S+ Sbjct: 668 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG 727 Query: 2635 TNGAESKTL-----IYQMAPAVSKTEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDS 2685 T A K + Q +P+ K P+ NP++ R P + P V + Sbjct: 728 TISAPGKVVTAAAQAKQRSPSKVKP----------PVRNPQNSTVLARGP-ASVPSVGKA 776 Query: 2686 VSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNP 2745 V+ A +D+ + + + T+ Q+ A E P Sbjct: 777 VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP 836 Query: 2746 VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFN--------YNPSPRKSSADS 2797 P +T S+ S SSS+ S G A VT +P+ + + Sbjct: 837 TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 896 Query: 2798 TSARPSQIPTPVNNNTKKRDSKTDSTES 2825 T A+ TP + +++ S+ES Sbjct: 897 TPAQAQAASTPRKARASESTARSSSSES 924 Score = 38.9 bits (89), Expect = 0.073 Identities = 71/329 (21%), Positives = 123/329 (37%), Gaps = 47/329 (14%) Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDE---KHVNS 2594 PI+ S + + E + + +T R ++SS+L A SS EKAK+E E K NS Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138 Query: 2595 I--SGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVS 2652 + T ++ N +S K + + + + S ++ S GA +K + A S Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198 Query: 2653 KTED------------------VWVRIEDCPI-NNPRSGRSPT--GNTPPVIDSV----- 2686 +ED + VR P P G +P G V Sbjct: 199 SSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 258 Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLN--SFIQVDAPDQKGTEIKPGQNN 2744 E + + ++S D++ + + + G +++ S ++P + PG+ Sbjct: 259 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318 Query: 2745 PVPV-------SETNESSIVERTPFSSSSSSKHSSPSGTV-AARVTPFNYNPSPRKSSAD 2796 P E ++SS E S + + PSG R SPRK +A Sbjct: 319 PAVAKAQAGKREEDSQSSSEESD--SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376 Query: 2797 STSARPSQIPTPVNNNTKKRDSKTDSTES 2825 + + V ++ DS++ S ES Sbjct: 377 APPRKTGPAAAQVQVGKQEEDSRSSSEES 405 >gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo sapiens] Length = 1008 Score = 57.8 bits (138), Expect = 2e-07 Identities = 129/593 (21%), Positives = 226/593 (38%), Gaps = 78/593 (13%) Query: 1960 PVCFSHNSSLS-------SLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSF 2012 P+C S ++S SL +D +++K + E P G+ + AP S Sbjct: 219 PLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSA 278 Query: 2013 HVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRL----KGDNEKHSPRNM 2068 D + R+ S + D + E + SA K +P L G + K+ P + Sbjct: 279 EKVDLVLSGKRDPGPSGKA----DPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSS 334 Query: 2069 G----GILG--EDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS----IVSSLHQA 2118 G G LG + L + D + + E+ + + A+S VS Sbjct: 335 GTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDT 394 Query: 2119 AAAACLSRQASSDSDSILSLK-SGISLGS--------PFHLTPDQEEKPFTSNKGPRILK 2169 A+A + + D + S K +SLG P L+P Q E+ G + Sbjct: 395 TASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGT--VS 452 Query: 2170 PGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRT 2229 PG++ + +++ + S G S T + N E SG+ P+ + P R Sbjct: 453 PGKEDPVSSRREDPISAG---------SRKTSSEKVNPESSGKTN-PVSSG-PGDPRSLG 501 Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289 P + +T KG PL + + + G+ A T+ A+P + PV++ Sbjct: 502 TAGPPSAVKAEPATGG---KGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGK 558 Query: 2290 SQIGGSSKAPSRS-GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRT 2348 + G S + S S G STP + P+ S + +S G+ P K+ LP Sbjct: 559 ADAGPSGQGDSVSIGKVVSTPGKTV------PVPSGKVDPVSLGKAEAIPEGKVGSLPLE 612 Query: 2349 SSPSTASTKSS--GSGKMSYTSPGRQMSQQNLTKQTGLSK--NASSIPRSESASKGLNQM 2404 +TK+ SGK S G+ ++ L Q G + A ++ + + ++ Sbjct: 613 KGSPVTTTKADPRASGKAQPQSGGK--AETKLPGQEGAAAPGEAGAVCLKKETPQASEKV 670 Query: 2405 NNG---------NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRK 2455 + G +G + V L + S S +ES + V + + K PS + R+ Sbjct: 671 DPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPL---SLEKTKPSSS-SRQ 726 Query: 2456 LEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508 L+ A + SP S R + + +S + + S ++A G + P Sbjct: 727 LDRKALGSARSPEGARGSEGRVEPKAEPVSST--EASSLGQKDLEAAGAERSP 777 Score = 39.3 bits (90), Expect = 0.056 Identities = 65/321 (20%), Positives = 118/321 (36%), Gaps = 32/321 (9%) Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK-----RQNQLHPSSAQSR-SG 1241 PS+ K + SS+ + +S + T S A+ +++ + A + SG Sbjct: 506 PSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSG 565 Query: 1242 QPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL--SSLSSAEDEIGCNQTTQEADS- 1298 Q + KV S +T+ + P+ + ++ + S E G TT +AD Sbjct: 566 QGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPR 625 Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358 A+ + K T+ + P + K Q S + KA +SG Sbjct: 626 ASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGK 685 Query: 1359 KSPSKSG----AQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS---------- 1404 P G A + K+ + PL + SS + +++ S+ Sbjct: 686 GEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSE 745 Query: 1405 ----VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVP--KNKAP 1458 ++EP S + + DL + + P + PPP P+T + P + AP Sbjct: 746 GRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAP 805 Query: 1459 TAEKRESGPK---QAAVNAAV 1476 + ++G + QA V+ AV Sbjct: 806 PPPREDAGTQAGAQACVSVAV 826 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 56.6 bits (135), Expect = 3e-07 Identities = 112/580 (19%), Positives = 210/580 (36%), Gaps = 88/580 (15%) Query: 2155 EEKPFTSNKGPRILKPGEKSTLETKKIESES---KGIKGGKKVYKS-----LITGKVRSN 2206 EE+ + + + EK E + E E + +GG++ KS + + + Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517 Query: 2207 SEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA---SKSPSE 2263 S + + K P +A P ++ + + S +K P K+P +KSP+E Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577 Query: 2264 GQTA----------------TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDS 2307 ++ SP AK VK E A S + +K+P+ S + Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Query: 2308 TPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYT 2367 A+ P +SP + SP + P K SP A KS K Sbjct: 638 -----AKSPTKEEAKSP-EKAKSPEKEEAKSPEK------AKSPVKAEAKSPEKAK---- 681 Query: 2368 SPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGS 2427 SP + ++ ++ + + A S +++S K K S K Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK----------EEAKSPEKAKSPVKEEAK 731 Query: 2428 ESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPS 2487 ++++ PV +EA SP + E++ + + SP ++ +P + +A++P + Sbjct: 732 TPEKAKSPVK-------EEAKSPEKAKSPEKAKTLDVKSPEAK--TPAKEEARSP--ADK 780 Query: 2488 LPDMSLS-THSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT 2546 P+ + S V++ K P L + + K+ ++ E + Sbjct: 781 FPEKAKSPVKEEVKSPEKAKSP--LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEP 838 Query: 2547 WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQV 2606 K+ + + + P+ + S A + + K K E++K ++ KE++V Sbjct: 839 PKKAEEEKAPATPKTEEKK----DSKKEEAPKKEAPKPKVEEKKE----PAVEKPKESKV 890 Query: 2607 SAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPI 2666 AK + K+ +P A +K + + A KTE +D Sbjct: 891 EAKKEEAEDKKKVPTPEKE------------APAKVEVKEDAKPKEKTEVAKKEPDDAKA 938 Query: 2667 NNPRSGRSPTGNTPPVIDSVSEKA-NPNIKDSKDNQAKQN 2705 P P D+ EKA P K + +AK++ Sbjct: 939 KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978 Score = 55.1 bits (131), Expect = 1e-06 Identities = 107/563 (19%), Positives = 204/563 (36%), Gaps = 76/563 (13%) Query: 1529 QENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSS 1588 +E + G E P E + EKEA+ + E ++ + E + S KS Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK----SPAEVKSP 547 Query: 1589 RKAKKPAQTASKLPPPV-------ARKPSQL--PVYKLLPSQNRLQ-------------P 1626 KAK PA+ +K PP A+ P+++ P P++ + P Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607 Query: 1627 QKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEK 1686 K + +P + V +P + T E + A + A+S E + Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE-KA 666 Query: 1687 RDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKI 1746 + + E +S ++A+ + PE + +E E S + K ++ P + K Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV-KEEAKSPEKAKSP 725 Query: 1747 MDQVQQASASSSAPNKNQLDG--KKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERV 1804 + + + + +P K + K K P ++ E +T ++ A S + E+ Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785 Query: 1805 FSDNKDSKKQNLKNNSKVFND-KLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLS 1863 S K+ K K S + D K P E + + + Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKE------------------------IPKKEEVK 821 Query: 1864 SLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQP 1923 S +++ + K +KA+E K A T TE + + + A +P + Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEK---APATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878 Query: 1924 KPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKE 1983 +P ++K P+ SK + A D+K + P + ++ ++ KE Sbjct: 879 EPAVEK----PKESKVEAKKEEAEDKKKVPTPEKEAP----------AKVEVKEDAKPKE 924 Query: 1984 NEPIKETEPPDSQG-EPSKP-QASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE 2041 + + EP D++ EPSKP + AP+ ++ + +D L + Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984 Query: 2042 CISSAMPKKKKPSRLKGDNEKHS 2064 + PK +K + ++K S Sbjct: 985 --EPSKPKAEKAEKSSSTDQKDS 1005 Score = 54.3 bits (129), Expect = 2e-06 Identities = 123/629 (19%), Positives = 222/629 (35%), Gaps = 110/629 (17%) Query: 1121 INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEER----------PTNYSIKYNEEK 1170 + + ++ E+ E+++ E EEE EEEE P + +E Sbjct: 457 VEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA 516 Query: 1171 RHVDQPIDYSLKYATDIPSSQKQ---------SFSFSKSSSGQSSKT--EHMSSSSENTS 1219 + P+ K + S +K+ S +KS + + +K+ E S E Sbjct: 517 K---SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573 Query: 1220 TPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSS 1279 +P+ + P+ +++S K+ K S +E ++ +P+ + + S Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPV---KEEAKSP 629 Query: 1280 LSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV-----------SEVPAVSQ 1328 E + T +EA S + E +E A+ PV S V A ++ Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689 Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSG---AKSPSKSGAQTP---KSPPEHYVQETPL 1382 P S ++ + S E A+ E + AKSP K A+TP KSP + ++P Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-KSPE 748 Query: 1383 MFSRCTSVSSLD--SFESRSIASSVQSEPCSGMVSGIISP-SDLPDSPGQTMPPSRSKTP 1439 +LD S E+++ A P SP + SP + P + Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808 Query: 1440 PPP---PQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496 P P+ + K V + + P K + PK+ A ++ P + E Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK----AEEEKAPATPKTEEKKDSKKEEA 864 Query: 1497 PDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT 1556 P +P +++ E + P + + E+E K+ EKEA Sbjct: 865 P----------KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED-KKKVPTPEKEAPAK 913 Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKK-PAQTASKLPPPVARKPSQLPVY 1615 ++ ++D A P + + AKK P +K P A K P Sbjct: 914 VEVKED-------------------AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954 Query: 1616 KLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGV 1675 K + +P ++ P+ D T+ P++ A + Sbjct: 955 KDTKEEKAKKP---------EEKPKT----------EAKAKEDDKTLSKEPSKPKAEK-- 993 Query: 1676 RGGAQSGEFEKRDTIPTEGRSTDEAQGGK 1704 +S +++D+ P E + D+A GK Sbjct: 994 --AEKSSSTDQKDSKPPEKATEDKAAKGK 1020 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 55.8 bits (133), Expect = 6e-07 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%) Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936 E RKA+E+ +AK T ++ S +S+ + + A+ + P+ S Sbjct: 58 ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113 Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996 D+P ++ EK + E + NS + N P K EP + Sbjct: 114 GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167 Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054 S+ + G P +F P V + S S + S D+ E S P + K S Sbjct: 168 TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226 Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110 + + K SP G +G D+T +K P ++ P+ E+ ++ +EG+ S Sbjct: 227 SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279 Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170 + A A S+ +S+ + S + G+P KG P Sbjct: 280 -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320 Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230 G+ + S++K GK +SE S + + P+ + + Sbjct: 321 GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359 Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290 + +S TS V P K K + T P AK + Sbjct: 360 LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415 Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 + +AP+++ P R A P +SP + + P Q+ + Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393 S +S++ S S GK P M L K G P Sbjct: 473 EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450 + SA G + ++ + + + + S + ++S +L + T P Sbjct: 533 TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592 Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499 + ++ S S E S S+ PA+ T +QA+ + P T+++ Sbjct: 593 GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652 Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538 A G P SP + RPA + + S ES S Sbjct: 653 SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709 Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598 + + ++ + + ++S+P V G++ + + + + K+E ++ S Sbjct: 710 VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768 Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653 S+E S +K+ + + ++ S+ T A K + Q +P+ K Sbjct: 769 SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828 Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709 P+ NP++ R P + P V +V+ A +D+ + + + Sbjct: 829 P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877 Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769 T+ Q+ A E P P +T S+ S SSS+ Sbjct: 878 EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937 Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821 S G A VT +P+ + +T A+ TP + +++ Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997 Query: 2822 STES 2825 S+ES Sbjct: 998 SSES 1001 Score = 51.2 bits (121), Expect = 1e-05 Identities = 153/744 (20%), Positives = 243/744 (32%), Gaps = 124/744 (16%) Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183 +ED K T S+ S E EEEE + K N D P K Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125 Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243 + + K S ++G++ S ++ PS+N ++ + G Sbjct: 126 KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185 Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303 K + + EDT SS S + E + +A S +T + Sbjct: 186 AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232 Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360 K D +V + P ++ + + S SSE E +G +S Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292 Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398 P K P +T P S +S S DS E Sbjct: 293 ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352 Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432 A ++ SG S + + S P PG+T P Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412 Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485 S + P A+ + P+ +A +A +ES K AA A +VQV Sbjct: 413 SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472 Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532 + + ES D +L+A++ + P ++ + + P PV Sbjct: 473 EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528 Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592 G T S Q + E+ E +E++ DS + + E I+ A PT S AK Sbjct: 529 VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586 Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651 P Q A + V A KP S + + + T P + + Sbjct: 587 GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646 Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711 T T+ S A VR G Q+ K T + S+ GG P Sbjct: 647 KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689 Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771 D + +EE D E A+ G++ K + +Q +A S P K L G+ Sbjct: 690 AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740 Query: 1772 PTSPVKPIPQNTEYRTRVRKNADS 1795 P P K P T+ + +++++S Sbjct: 741 PVLPGKTGPTVTQVKAEKQEDSES 764 Score = 50.8 bits (120), Expect = 2e-05 Identities = 154/804 (19%), Positives = 274/804 (34%), Gaps = 109/804 (13%) Query: 1202 SGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261 S Q K E S SS S+ SS+ + + P+ +S Q T + + Sbjct: 535 SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGP 594 Query: 1262 YCVE---DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAED 1318 V+ + P+ S S SS S+ +E T +A A + + K +A Sbjct: 595 VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 654 Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378 V+ V +Q PR + + +S + AV + G + P++ + + +S E + Sbjct: 655 KVAPVRVGTQAPR------KAGTATSPAGSSPAV--AGGTQRPAEDSSSSEESDSEE--E 704 Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438 +T L ++ +++S+ +Q + S V G + P P KT Sbjct: 705 KTGL---------AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP--------GKT 747 Query: 1439 PPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPD 1498 P Q K+E ++ ++ E+ A V +V++ Q + A P Sbjct: 748 GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP------AAARAPS 801 Query: 1499 GFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQ--EKEAEKT 1556 S+ + ++ ++ PPV+ N + + A+ Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQ 861 Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLP-------PPVARKP 1609 E+D ++ D E E + P+ + + + A + P PP P Sbjct: 862 TGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP 921 Query: 1610 SQLPVYKLLPSQNRLQPQKHVSFTPGD------DMPRVYCVEGTPINFSTATSLSDLTIE 1663 S K S + + P P + V+ A + + Sbjct: 922 SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 981 Query: 1664 SPPNELAAGEGVRGGAQSGEFEKRDTIP-----TEGRSTD--------------EAQGGK 1704 S P + A E + S E E D IP T G T+ + G Sbjct: 982 STPRKARASEST-ARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 1040 Query: 1705 TSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQ 1764 +SS + D K +EG K + P + Q+AS + + Q Sbjct: 1041 SSSKESSRISDGKKQEGP-----ATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQ 1095 Query: 1765 LDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFN 1824 S V +P + T V+ A N L ++ + +K ++S+ + Sbjct: 1096 ---PSSGVDSAVGTLPATSPQSTSVQ--AKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150 Query: 1825 DKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSL---SSLDFDDDDV--------- 1872 D +E+ G S H P TP SR ++L ++ + +DDV Sbjct: 1151 DSSSGSEEDGEGPQGAKSAHTLGP---TP---SRTETLVEETAAESSEDDVVAPSQSLLS 1204 Query: 1873 -----DLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPIL 1927 L+ ++ KA +S V+S L + K +A +Q PK Sbjct: 1205 GYMTPGLTPANSQASKATPKLDSSPSVSS--TLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1262 Query: 1928 QK--QSTFPQSSKDIPDRGAATDE 1949 ++ T PQ S+ P +GA + Sbjct: 1263 KEAASGTTPQKSRK-PKKGAGNPQ 1285 Score = 37.4 bits (85), Expect = 0.21 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%) Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591 PI+ S + + E + + +T R ++SS+L A SS EKAK+E EK Sbjct: 81 PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138 Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631 N +SG K + SA T E E S S Q S Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198 Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689 S + S + P+V ++ + V ++ P G+ P + + Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258 Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738 K ++ G+ S G +++ + +QV A P + T Sbjct: 259 PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318 Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783 PG+ V S+T E + SS SS K S + V A P Sbjct: 319 PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377 Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829 SPRK +A + + ++ DS++ S ES + Sbjct: 378 AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421 Score = 37.4 bits (85), Expect = 0.21 Identities = 54/221 (24%), Positives = 89/221 (40%), Gaps = 24/221 (10%) Query: 2235 GVRNSSSSTSPVS----KKG---PPLKTPASKSPSE----GQTATTSPRGAKPSVKSELS 2283 G + ++S T+P KKG P T A +S GQ + + SV L+ Sbjct: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320 Query: 2284 PVARQT-SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP--PN 2340 + Q ++ ++K SR G QP +R +S + + G G + P Sbjct: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380 Query: 2341 KLSQLPRTSSPSTASTKSSGS-----GKMSYTSPG-RQMSQQNLTKQTGLSKNAS-SIPR 2393 K S TS K+SG GK S S G + ++ L K G + S P+ Sbjct: 1381 KTST---TSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPK 1437 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSER 2434 S+ K ++ +K + ++ +STK S S S + ++ Sbjct: 1438 SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1478 >gi|120953251 neuron navigator 3 [Homo sapiens] Length = 2363 Score = 55.8 bits (133), Expect = 6e-07 Identities = 144/604 (23%), Positives = 237/604 (39%), Gaps = 115/604 (19%) Query: 2046 AMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQ 2105 A +K + LKG + + SP + G G++ ++P S G S + +F +K Sbjct: 1019 AKASEKGKAPLKGSSLQRSPSDAGKSSGDEG-------KKPPSGIGRSTATSSFGFKK-- 1069 Query: 2106 EGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGP 2165 S + +A +S S ++ + ++G + + + N+ Sbjct: 1070 ------PSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSN-AGRKTSLDGSQNQDD 1122 Query: 2166 RILKPGEKSTLETKKIESESK----GI--KGGKKVYKSLI------------TGKVRSNS 2207 +L K+TL+ + + SK GI +GG + S I T K+R + Sbjct: 1123 VVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPT 1182 Query: 2208 EISGQMKQPLQANMP-------SISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260 +I P+ N ++S ++ ++S +S S +G L+ P SK Sbjct: 1183 KIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQG--LRQPGSKY 1240 Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320 P GAK KS +P T + SS PS S +T +R Q L P Sbjct: 1241 PDIASPTFRRLFGAKAGGKSASAP---NTEGVKSSSVMPSPS----TTLAR--QGSLESP 1291 Query: 2321 IQSPGRNSISPGRNGISPP--NKLSQLPR---------TSSPSTASTKSSG----SGKMS 2365 G + G +G S P NK S L SSP++ + +SG + MS Sbjct: 1292 SSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMS 1351 Query: 2366 YTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425 +S G + + T L ++ SI S L+ + G + + L R S +S+ Sbjct: 1352 SSSAGSK-DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSL-LMRTGSVRST 1409 Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485 SES + +R L ++ +P+ R+ +E S S+ T + Q+P++S Sbjct: 1410 LSESMQLDRNTLPKKGL----RYTPSSRQANQEEGKEWLRSHSTGGLQDTGN--QSPLVS 1463 Query: 2486 PSLPDMSLSTHSSVQAGGWR----KLPPNLS------PTIEYNDGRPAKRHDI------- 2528 P S SS AG + P NLS P++ ++ PA+ Sbjct: 1464 P-------SAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQ 1516 Query: 2529 ----ARSHSESPSRLPINRSGTWKREHSK-HSSSLPRVSTWRRTGSSSSILSASSESSEK 2583 A S E P I+ SG+++ + H SSL VS S+SS+ S + EK Sbjct: 1517 LCGSATSLEERPR--AISHSGSFRDSMEEVHGSSLSLVS------STSSLYST---AEEK 1565 Query: 2584 AKSE 2587 A SE Sbjct: 1566 AHSE 1569 Score = 40.4 bits (93), Expect = 0.025 Identities = 134/641 (20%), Positives = 238/641 (37%), Gaps = 113/641 (17%) Query: 2250 GPPLKTPASKSPSE----GQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSR 2305 G KT +S P + GQ A+ S + + + Q G+S + + Sbjct: 958 GGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017 Query: 2306 DSTPSRPAQQPL--SRPIQSPGRNSISPGRNGISPPNKLSQLPRTSS------------- 2350 D+ S + PL S +SP S G G PP+ + + TSS Sbjct: 1018 DAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSA 1077 Query: 2351 --PSTASTKSSGSGKM----------SYTSPGRQMSQQNLTKQTGLSKNAS--------S 2390 S+ +T +SGS + ++ GR+ S Q + + S S Sbjct: 1078 MITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRS 1137 Query: 2391 IPR-SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449 +PR S+S++ G+ G + + S+KS+G+ + + P + + Sbjct: 1138 LPRPSKSSTSGI--PGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVN 1195 Query: 2450 PTLRRKLEESAS-FESLSPSSRP-ASPTRSQA-------QTPVLSPSLPDMSLSTHSSVQ 2500 T + K + + S ES+S S P +SPT + A Q P + + + Sbjct: 1196 QTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAK 1255 Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHS-ESPSRLPINRSGTWKREHSKHSSSLP 2559 AGG PN + ++ + P+ +AR S ESPS SGT Sbjct: 1256 AGGKSASAPN-TEGVKSSSVMPSPSTTLARQGSLESPS------SGTGSMG--------- 1299 Query: 2560 RVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENE 2619 S +GSSS + + S+ + S +S++ + S + S W Sbjct: 1300 --SAGGLSGSSSPLFNKPSDLTTDVISLS----HSLASSPASVHSFTSGGLVW------- 1346 Query: 2620 FSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNT 2679 N +S + S T +S T ++ + ++ D P+++ S T T Sbjct: 1347 --AANMSSSSAGSKDTPSYQSMTSLHTSSESI-----------DLPLSHHGSLSGLTTGT 1393 Query: 2680 PPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIK 2739 V + + S+ Q +N ++P + GL +S A ++G E Sbjct: 1394 HEVQSLLMRTGSVRSTLSESMQLDRN----TLPKK--GLRYTPSS---RQANQEEGKEWL 1444 Query: 2740 PGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTS 2799 + N+S +V + SSS++ K+ + ++ FN P P + Sbjct: 1445 RSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNL-PGP-------SM 1496 Query: 2800 ARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPK--RHSGSY 2838 R + IP ++ DS+ + +S + P+ HSGS+ Sbjct: 1497 MRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSF 1537 Score = 39.3 bits (90), Expect = 0.056 Identities = 193/1032 (18%), Positives = 360/1032 (34%), Gaps = 139/1032 (13%) Query: 1879 AELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSK 1938 +E +AK ++ ++ + + SN +Q K+P P S P + Sbjct: 210 SEASQAKTQQDMQSSLAARYATQSNHSGIATSQ---KKPTRLPGP-------SRVPAAGS 259 Query: 1939 DIPDRGAAT-DEKLQNFAI--ENTPVCFSH-NSSLSSLSDIDQENNNKENEPIKETEPPD 1994 +GA+ + + Q+F +N P +++ N SS N +P P Sbjct: 260 SSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPP 319 Query: 1995 SQGEPSKPQASGYAPKSFHVED--TPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKK 2052 + PS + + KS +V+ T + S ++ S D L+ +S + Sbjct: 320 ASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGV----- 374 Query: 2053 PSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSP-----DSENFDWKAIQEG 2107 K +P +L + ++ + RP P D + F EG Sbjct: 375 ---------KTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEG 425 Query: 2108 ANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRI 2167 NS ++S ++ +S + + +L + SL P +K + P Sbjct: 426 FNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVK 485 Query: 2168 LKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRG 2227 + + + + KK + I G K + + S+S I + +P++ + Sbjct: 486 EEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKP-----GSKVPTVKQT 540 Query: 2228 RTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVAR 2287 + PG S S + KG P ++ + E +A++ P + + SP Sbjct: 541 IS----PGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASP--- 593 Query: 2288 QTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPR 2347 GS S ST + Q P + P +++P N+ + LP Sbjct: 594 -----SGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPS 648 Query: 2348 TSSPSTASTKSSGSGKMSYTSPGRQ-----MSQQNLTKQTGLSKNASSIPRS-ESASKGL 2401 S T+ TK +SY+ +Q + T++ KN + + ++ E L Sbjct: 649 ADS-CTSPTKMD----LSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSL 703 Query: 2402 NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPV-----LVRQSTFIKEAPSPTLRRKL 2456 + + S +++ + + + + RP L + ++ +P+L Sbjct: 704 RGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY 763 Query: 2457 EESAS--FESLSPSS-RPASPTRSQAQTPVLSPSLPDMS------LSTHSSVQAGGWRKL 2507 S + F PS +P R A + + + S DMS L S V GG+ Sbjct: 764 PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823 Query: 2508 PPNLSPTIEYNDGRPAKRHDIARS-HSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRR 2566 L ++ +D D + ++ S +R+P + + H ++ +W Sbjct: 824 GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVD-ADSW-- 880 Query: 2567 TGSSSSILSASSESSEKAKSEDEKHVNSISG-------------TKQSKENQVSAKGTW- 2612 SSS+ S S++ + ++D +S+S + E + + TW Sbjct: 881 -DDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWD 939 Query: 2613 ----RKIKENEFSPTNSTS---QTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCP 2665 K E +F +TVSSG E + + +VS+T W R Sbjct: 940 SPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAG--QKASLSVSQTGS-WRRGMSAQ 996 Query: 2666 INNPRSGRSPTG--NTPPVID--SVSEKANPNIKDSKDNQAKQNVG-----NGSVPMRTV 2716 P ++ T TP D SEK +K S ++ + G G P + Sbjct: 997 GGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGI 1056 Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGT 2776 G +SF P G+ + + T+ S+ + + P S++ K ++ T Sbjct: 1057 GRSTATSSF-GFKKPSGVGSSAMITSSG---ATITSGSATLGKIPKSAAIGGKSNAGRKT 1112 Query: 2777 --------------VAARVT-PFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821 V+++ T + P P KSS R ++T DS Sbjct: 1113 SLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGH-----RSSTSSIDSNVS 1167 Query: 2822 STESSGTQSPKR 2833 S + T S R Sbjct: 1168 SKSAGATTSKLR 1179 Score = 32.0 bits (71), Expect = 8.9 Identities = 54/243 (22%), Positives = 94/243 (38%), Gaps = 24/243 (9%) Query: 55 IEDEAMASS--GQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSP 112 + AM+SS G+ + NL N PG + S+ + S S Sbjct: 1462 VSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSA 1521 Query: 113 VPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDK--EEKEKDWYYAQLQNLTKRID 170 + PR +GS + +EE+ L++ E+ + Q+ L + + Sbjct: 1522 TSLEERPRAISHSGSFRDS--MEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRREL- 1578 Query: 171 SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILR 230 + E + T QL A + A E+ LG +M R Q +Q E +++ Sbjct: 1579 -VASQEKVATLTS----QLSANAHLV-AAFEKSLG---NMTGRLQSLTMTAEQKESELIE 1629 Query: 231 IRQ---LLQSQATEAERSSQNKHETGSHDAE-----RQNEGQGVGEINMATSGNGQGSTT 282 +R+ +L++Q + A+ + Q H + RQ+ + V IN ATS + GS Sbjct: 1630 LRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGN 1689 Query: 283 RMD 285 D Sbjct: 1690 DAD 1692 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 55.5 bits (132), Expect = 8e-07 Identities = 352/1860 (18%), Positives = 641/1860 (34%), Gaps = 318/1860 (17%) Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSS-------------AQSRSGQPQKAATCKV 1251 +S ++ S+S T S + K +++PS+ +S S P + KV Sbjct: 6560 ASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKV 6619 Query: 1252 SSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI------GCNQTTQEADSANTLQIA 1305 +S + ++ + DT + S S S ++ E E G T+ D + + + Sbjct: 6620 TS---PMVTSFNIRDTIVSTSMPGS-SEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKS 6675 Query: 1306 EIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHK-----AVEFSSGAKS 1360 + K+ T + E +EV + ++ + + G S+ES ++ S G Sbjct: 6676 AVLHKLTTGATETSRTEVAS------SRRTSIPGPDHSTESPDISTEVIPSLPISLGITE 6729 Query: 1361 PSKSGAQTPKSPP------EHYVQETPLMFSRC-TSVSSLDSFESRSIASSVQSEPCSGM 1413 S T PP + +TP SR T + F + + + +P + Sbjct: 6730 SSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDP--EI 6787 Query: 1414 VSGIISPS--------DLPDSPGQTMPPSRSKTP------PPP------PQTAQTKREVP 1453 +S I PS L SP T PP S P P P P T + Sbjct: 6788 LSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLG 6847 Query: 1454 KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE 1513 + PT S P ++ + + A +H +T + +SS S Sbjct: 6848 TSPEPTTS---SPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHG-SQSS 6903 Query: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573 + P + G+ T S S+E + + E T L + S + Sbjct: 6904 VLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNAS 6963 Query: 1574 ILEEC--IISAMPTKSSRKAKKPAQTAS---KLPPPVARKPSQLPVYKLLPSQNRLQPQK 1628 + ++S +PT ++ + + T+S +P P SQ V + ++ + Sbjct: 6964 FSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGP-----SQSTVLPEISTRTMTRLFA 7018 Query: 1629 HVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRD 1688 + T +M T S +TS LT+++ + A Sbjct: 7019 SPTMTESAEM-----TIPTQTGPSGSTSQDTLTLDTSTTKSQA---------KTHSTLTQ 7064 Query: 1689 TIPTEGRSTDEAQG-GKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIM 1747 P +T ++G G S + P L+ N + +L+ ++ P S P + Sbjct: 7065 RFPHSEMTTLMSRGPGDMSWQSSPSLE-NPSSLPSLLSLPATTSPPPISSTLPVTISSSP 7123 Query: 1748 DQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN-AERVFS 1806 V SS + L + TS + ++ R K+ + ++ + + Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183 Query: 1807 DNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFS----RNDSL 1862 N + ++ S D F + T TP+ + +S+ Sbjct: 7184 SNVEIPSSGHESPSSALADS--ETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESI 7241 Query: 1863 SSLDFDDDDVDLSRE------------KAELRKAKENKESEAKVTSHTELTSNQQSANKT 1910 SSL + S E + + E +E +S T ++ + +S Sbjct: 7242 SSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLP 7301 Query: 1911 QAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTP-VCFSHNSSL 1969 + + I + PIL + S ++ P +T E TP + +H++ Sbjct: 7302 EISTTRKIIKFPTSPILAESSEMTIKTQTSPP--GSTSESTFTLDTSTTPSLVITHSTMT 7359 Query: 1970 SSL--SDIDQENNNKENE-------PIKETEPPDSQ----GEPSKPQASGYAPKSFHVED 2016 L S+I + + P++ET PP SQ S S P S H Sbjct: 7360 QRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSS 7419 Query: 2017 TPVC---------------------FSRNSSLSSLSID--------SEDDLLQECISSAM 2047 V S SLSS S++ ++ + + ++A+ Sbjct: 7420 ASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAV 7479 Query: 2048 PK-------KKKPSRLKGDNEKHSPRNMGG---ILGE----DLTLDLKDIQRPDSEHGLS 2093 K + PS + D+E + G I+G+ LT L + ++ SE S Sbjct: 7480 TKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASS 7539 Query: 2094 -----PDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILS------LKSGI 2142 ++ + ++ AN+++S + A +A S S + +S + I Sbjct: 7540 LTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDI 7599 Query: 2143 SLG-----SPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKS 2197 S+G S + + + T+ GP +STLE+ + + + + Sbjct: 7600 SIGTIPRISASSVLTESAKMTITTQTGP------SESTLES-TLNLNTATTPSWVETHSI 7652 Query: 2198 LITG-----KVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPP 2252 +I G S G + P + S + + +P V + ++ PP Sbjct: 7653 VIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPP 7712 Query: 2253 LKTPASKSPSEGQTATTSPRGAK----PSVKSELSPVARQ----------------TSQI 2292 P + + G TT G S S LS + + ++ Sbjct: 7713 SPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNT 7772 Query: 2293 GGSSKAPSRSGSR-------DSTP--------------SRPAQQPLSRPIQSPGRNSISP 2331 GG++ A + SG + DS+P S PA +R IQ+ +S++P Sbjct: 7773 GGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLE-TRRIQTELASSLTP 7831 Query: 2332 ------GRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLS 2385 G G S K+S + + P+ A+T+ S S P + +++ +T +S Sbjct: 7832 GLRESSGSEGTSSGTKMSTV-LSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRT-VS 7889 Query: 2386 KNASSIPRSESASKGLNQMNNGNGANKK--VELSRMSSTKSSGSESDRSERPVLVRQSTF 2443 ++S +ESA +N + GA + L S+T + + S S+ + ST Sbjct: 7890 WFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTL 7949 Query: 2444 IKEAP------SPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHS 2497 ++ P SP L K S S S SP++ SP S + S LP SL T Sbjct: 7950 MRRGPEDVSWMSPPLLEKTRPSFSLMS-SPATTSPSPVSSTLPESISSSPLPVTSLLTSG 8008 Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT----------- 2546 AK D+ SE + P N S T Sbjct: 8009 L------------------------AKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVT 8044 Query: 2547 --WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE-------KAKSEDEKHVNSISG 2597 ++ H + ++ V T S+S + A S++S+ + ED S G Sbjct: 8045 TDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPG 8104 Query: 2598 TKQSKENQVSAKGT----WRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653 ++ Q + RK +E + + TV SG GA ++ ++ + Sbjct: 8105 FFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRT 8164 Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713 + + ++ P + + T P ++E A IK D +V + Sbjct: 8165 SISGFAQLTVSPETS-----TETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDI 8219 Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSP 2773 T +S + + T + +P + ++SS+ E +SS+SS S P Sbjct: 8220 STTPNWVETHSTVTQRFSHSEMTTLV--SRSPGDMLWPSQSSVEE----TSSASSLLSLP 8273 Query: 2774 SGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKR 2833 + T + V+ P S ++ P + T + R+ T ST + + S +R Sbjct: 8274 ATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVIT-TDRMGISREPGTSSTSNLSSTSHER 8332 Score = 52.4 bits (124), Expect = 6e-06 Identities = 146/688 (21%), Positives = 250/688 (36%), Gaps = 124/688 (18%) Query: 2205 SNSEISGQM-KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPP-LKTPASK--- 2259 S S +S +M K P ++P S T ++ ++ PV+ GPP L T AS Sbjct: 2188 SESLVSFRMNKDPWTVSIPLGSHPTT---------NTETSIPVNSAGPPGLSTVASDVID 2238 Query: 2260 SPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSR 2319 +PS+G + P+V SP T+ S P ++ T S + SR Sbjct: 2239 TPSDGAESI-------PTVSFSPSPDTEVTT----ISHFPEKTTHSFRTISSLTHELTSR 2287 Query: 2320 PIQSPG---RNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQ 2376 PG +++S G SP L + R + S A T S S+T Sbjct: 2288 VTPIPGDWMSSAMSTKPTGASPSITLGE--RRTITSAAPTTSPIVLTASFTETSTVSLDN 2345 Query: 2377 NLTKQTGL---SKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSE 2433 T +T ++ + +P S+S L N + S M TK++ Sbjct: 2346 ETTVKTSDILDARKTNELPSDSSSSSDL--------INTSIASSTMDVTKTASI------ 2391 Query: 2434 RPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSL 2493 SPT + S+S SL S RP PT + SPS+ + Sbjct: 2392 ---------------SPTSISGMTASSS-PSLFSSDRPQVPTSTTETNTATSPSVSSNTY 2435 Query: 2494 STHSSVQAGGW-RKLPP-NLSPTIEYND-----GRPAKRHDIARSHSESPSRLPINRSGT 2546 S GG LPP ++ +E + RP + S + P + + Sbjct: 2436 SLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSV 2495 Query: 2547 WKREHSKHSSSLPRVSTWRRTGSSSSI-------LSASSESSEKAKSEDE------KHVN 2593 +S+P TW GS++ + S + E+ S E H++ Sbjct: 2496 --------VTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLS 2547 Query: 2594 S--ISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651 + ++G+ + E + + I + +PT TS ++ T+ L+ Sbjct: 2548 AAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSG--ANWETSATPESLLVVTETSDT 2605 Query: 2652 SKTEDVWV-------RIEDCPINNPRSGRSPTGNTP------PVIDSVSEKANPNIKDSK 2698 + T + V + P P +G + P P I + + ++ S Sbjct: 2606 TLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF 2665 Query: 2699 DNQAKQNVGN---GSVPMRTVGLENRLNS----FIQVDAPDQK--GTEIKPGQNNPVPVS 2749 D+ + + G+VP T+ + N V PD+ G I+ +P+ S Sbjct: 2666 DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPS 2725 Query: 2750 ETNESSIV--ERTPFSSSSSSKHSS-PSGTVAARVTPFNYNPSPRKSSADSTSARPSQIP 2806 T+ S IV T + S + S+ P+GT + V + S + DS++ Sbjct: 2726 STSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASV 2785 Query: 2807 TPVNNNTKKRDS----KTDSTESSGTQS 2830 P+ ++ S ++ ST S+GT++ Sbjct: 2786 MPLTTGSQGMASSGGIRSGSTHSTGTKT 2813 Score = 50.1 bits (118), Expect = 3e-05 Identities = 148/686 (21%), Positives = 260/686 (37%), Gaps = 108/686 (15%) Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKP----FTSNKGPRILKPGEK--STLET 2178 S + +S S++SL S ++ SP + TP + TS P ++K + ++LE Sbjct: 8846 SVEKTSPPSSLVSL-SAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEP 8904 Query: 2179 KKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSIS-RGRTMIHIPGVR 2237 S I + SL T K +E + M +IS R PG+ Sbjct: 8905 VTTSPPSMNITSDE----SLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLP 8960 Query: 2238 NSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSK 2297 S TSPV + S + +TT P SE++ + +++ S+ Sbjct: 8961 EPSKVTSPV----------VTSSTIKDIVSTTIP------ASSEITRIEMEST----STL 9000 Query: 2298 APSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK 2357 P+ P + S+ I S + S P + S T S Sbjct: 9001 TPT-----------PRETSTSQEIHSATKPSTVPYKALTSA---------TIEDSMTQVM 9040 Query: 2358 SSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417 SS G SP + Q+++ + +++ ++S ++ES + GA + L+ Sbjct: 9041 SSSRGP----SPDQSTMSQDISTEV-ITRLSTSPIKTESTEMTITTQTGSPGATSRGTLT 9095 Query: 2418 RMSSTK-SSGSESDRSERPVLVRQSTFIKEAPS--PTLRRKLEE---SASFESLSPSSRP 2471 +ST SG+ S S+ + + + P P L E SASF SP Sbjct: 9096 LDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTS 9155 Query: 2472 ASPTRSQAQTPVLSPSLPDMSLSTHSSVQ--------AGGWRKLPPNLSPTIEYNDGRPA 2523 +SP S + S SLP SL T V+ + PPNLS T A Sbjct: 9156 SSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSST-------SA 9208 Query: 2524 KRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS--------SSSILS 2575 + I +++ +L + T H SS L T + T S +++L+ Sbjct: 9209 EILAITEVTTDT-EKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLT 9267 Query: 2576 ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGAT 2635 ++ S+ ++ + + ++ G ++ ++ ++ T K PT +T++ + A Sbjct: 9268 STPAFSDTSRIQTKSKLSLTPGLMETSISEETSSAT-EKSTVLSSVPTGATTEVSRTEAI 9326 Query: 2636 NGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIK 2695 + S+T I A + ++ I I+ P + + T +++ K P+ Sbjct: 9327 --SSSRTSIPGPAQSTMSSDTSMETI--TRISTPLTRKESTDM------AITPKTGPSGA 9376 Query: 2696 DSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE-------IKPGQNNPVPV 2748 S+ + S P R + V P +G E + +N+P P Sbjct: 9377 TSQGTFTLDSSSTASWPGTHSATTQRFPQSV-VTTPMSRGPEDVSWPSPLSVEKNSP-PS 9434 Query: 2749 SETNESSIVERTP-FSSSSSSKHSSP 2773 S + SS+ +P +S+ S S HSSP Sbjct: 9435 SLVSSSSVTSPSPLYSTPSGSSHSSP 9460 Score = 49.3 bits (116), Expect = 5e-05 Identities = 141/642 (21%), Positives = 235/642 (36%), Gaps = 91/642 (14%) Query: 2221 MPSISRGRTMIHIPGV-RNSSSSTSPVSK--KGP---PLKTPASKSPSEGQTATTSPRGA 2274 MPS+S T GV R S S SP S+ GP L T A PS +T P + Sbjct: 10279 MPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPS----STPVPFSS 10334 Query: 2275 KPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN 2334 ++ S + +I SS P R + T S + L Sbjct: 10335 STFTTTDSSTIPA-LHEITSSSATPYRVDTSLGTESSTTEGRLVM--------------- 10378 Query: 2335 GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQN--LTKQTGLSKNASSIP 2392 +S + SQ RTSS T+ + S ++ + Q+ + LT+ G+ ++ + IP Sbjct: 10379 -VSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIP 10437 Query: 2393 RSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTL 2452 +E+A +G + G + + G++ + L +T +K TL Sbjct: 10438 -NEAAHRGT--IRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATL 10494 Query: 2453 RRKLEESA--SFESLSPSSRPAS--PTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508 + + L+ S + AS PT TP + P +P+ + S +S+ A Sbjct: 10495 TTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGA------- 10547 Query: 2509 PNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTG 2568 E + P + SE+ + L ++RSG E S +L S+ T Sbjct: 10548 -------ETSTALPRTTPSVFNRESETTASL-VSRSGA---ERSPVIQTLDVSSSEPDTT 10596 Query: 2569 SSSSILSASSESSEKAKSEDEKH--VNSISGTKQSKENQVSAKGTWRKIKENEFSPTNST 2626 +S I A + + + + H ++++S T S VS+ I +E T Sbjct: 10597 ASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSS-AIPTNISPSELDAL--T 10653 Query: 2627 SQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686 SG TL +P ++T W + +P S T P Sbjct: 10654 PLVTISGTDTSTTFPTL--TKSPHETETRTTW-------LTHPAETSSTIPRTIPNFSHH 10704 Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTV--GLENRLNSFIQVDAPDQKGT----EIKP 2740 A P+I S + + ++P+ TV G E+ + S + D+ T + P Sbjct: 10705 ESDATPSIATSPGAET-----SSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSP 10759 Query: 2741 GQNNP----VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFN---YNPSPRKS 2793 G+ V E SS + + S + S +S ++AA+ + N N + Sbjct: 10760 GEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPA 10819 Query: 2794 SADSTSARPSQIPTPVNNNT-----KKRDSKTDSTESSGTQS 2830 + S P+Q V T K D+ T S G +S Sbjct: 10820 TTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAES 10861 Score = 48.1 bits (113), Expect = 1e-04 Identities = 128/633 (20%), Positives = 226/633 (35%), Gaps = 102/633 (16%) Query: 2231 IHIPGVRNSSSSTSPVSKKGPPL---KTPASKSPSEGQTATT---SPRGAKPSVKSELSP 2284 IH G S SS SP + P + KT S S T+ + + PSV + Sbjct: 821 IHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETS 880 Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQ 2344 V+R + + +S + D+ P+R AQ S + +S+ Sbjct: 881 VSRVRTTLASTSVPTPVFPTMDTWPTRSAQ---------------------FSSSHLVSE 919 Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404 L TSS S ++ S K+S+ + MSQ N + N S+ P+S + + + Sbjct: 920 LRATSSTSVTNSTGSALPKISHLTGTATMSQTNRD-----TFNDSAAPQSTTWPETSPRF 974 Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEE-SASFE 2463 G L ++T S+ + S V S F A S + E S + Sbjct: 975 KTG--------LPSATTTVSTSATS----LSATVMVSKFTSPATSSMEATSIREPSTTIL 1022 Query: 2464 SLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPA 2523 + ++ P S + P+ + + L T LP + + E + Sbjct: 1023 TTETTNGPGSMAVASTNIPIGKGYITEGRLDT---------SHLPIGTTASSETSMDFTM 1073 Query: 2524 KRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEK 2583 + ++ S S S S ++ +G SS+ R S + T S S E + Sbjct: 1074 AKESVSMSVSPSQS---MDAAG---------SSTPGRTSQFVDTFSDDVYHLTSREITIP 1121 Query: 2584 AKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG--ATNGAESK 2641 ++ T + SA+ TW I + SP++ T + S +T + Sbjct: 1122 RDGTSSALTPQMTATHPPSPDPGSARSTWLGILSS--SPSSPTPKVTMSSTFSTQRVTTS 1179 Query: 2642 TLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQ 2701 ++ + + ++ P N P SG P+ D+ Sbjct: 1180 MIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPL-------------DTPSPA 1226 Query: 2702 AKQNVGNGSVPMRTVGLEN------RLNSFIQVDAPD----QKGTEIKPGQNNPV--PVS 2749 G +P + E+ L + ++P + +KPG P+ P Sbjct: 1227 TSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSI 1286 Query: 2750 ETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPV 2809 ET+ R +SS SS + ++P T T ++P+ ++ D +Q+ TP Sbjct: 1287 ETHIHVSTARMAYSSGSSPEMTAPGET----NTGSTWDPTTYITTTDPKDTSSAQVSTPH 1342 Query: 2810 NNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTS 2842 + T + TES+ +P +SGS ++S Sbjct: 1343 SVRTLRTTENHPKTESA---TPAAYSGSPKISS 1372 Score = 47.8 bits (112), Expect = 2e-04 Identities = 331/1770 (18%), Positives = 603/1770 (34%), Gaps = 257/1770 (14%) Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSA 1236 +D SL+ T P S + +S ++ E T+ PS N N SA Sbjct: 4790 VDTSLETVTSSPQSMSNTLDDISVTSAATTDIE--------TTHPSINTVVTNVGTTGSA 4841 Query: 1237 -QSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQE 1295 +S S KV+S N + T +EDT I S S S + E E + T + Sbjct: 4842 FESHSTVSAYPEPSKVTSPN---VTTSTMEDTTISRSIPKS-SKTTRTETETTSSLTPKL 4897 Query: 1296 ADSANTLQIAEIKEKIGTRSAEDPVSEVP-AVSQHPRTKSSRLQGSSLSSESARHKAVEF 1354 +++ + +I T ++ P E+ A ++ RT + +S +++ Sbjct: 4898 RETSISQEITS-----STETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDI 4952 Query: 1355 SSGAKSP-SKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGM 1413 S+ + S S T + Q P +S D+F ++ Q+ S M Sbjct: 4953 STETNTRLSTSPIMTESAEITITTQTGP------HGATSQDTFTMDPSNTTPQAGIHSAM 5006 Query: 1414 VSGIIS------PSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTA-EKRESG 1466 G S +P T PPS KT P + P + T E + S Sbjct: 5007 THGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSS 5066 Query: 1467 PKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMP 1526 P + + + + V++ T L T S P+ S S + A S D KD + I P Sbjct: 5067 PMTSLLTSGL--VKITDILRTRLEPVTSSLPNFSSTSDKILATSKDS----KDTK-EIFP 5119 Query: 1527 P-------VQENDNGNET------ESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573 V+ N++G+E+ +SE PK + + + + Sbjct: 5120 SINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTN 5179 Query: 1574 ILEECIISAMP----TKSSRKAKKPAQTA---SKLPPPVARKPSQLPVYKLLPSQNRLQP 1626 I E P T +S+++ P T+ SK+P + S V S P Sbjct: 5180 IKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNS---SSKISTP 5236 Query: 1627 QKHVSFTPGD----DMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSG 1682 S P D ++PRV+ + T ++ +T ++ P E A+ + Sbjct: 5237 DHDKSTVPPDTFTGEIPRVFTS-----SIKTKSAEMTITTQASPPESASHSTL------- 5284 Query: 1683 EFEKRDTIPTEGRSTDEAQG--------------GKTSSVTIPELDDNKAEEGDILAEC- 1727 + T+ G + QG G S +T P +++ + + + Sbjct: 5285 PLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAM 5344 Query: 1728 -----INSAMPKGKSHKPFRVKKIMDQV-----------QQASASSSAPNKNQLDGKKK- 1770 ++S P+ P V + V S +SS PN + + ++ Sbjct: 5345 TSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPA 5404 Query: 1771 --KPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLP 1828 K T+ + ++ + + V +D++ SK L + + D Sbjct: 5405 TYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDT-- 5462 Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888 V S S + E T R S+ + + + + + + Sbjct: 5463 ----SVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQ 5518 Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQK--------QSTFPQSSKDI 1940 S +++S S+ I+ I R PI+ K Q+T P ++ Sbjct: 5519 ASRTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQG 5578 Query: 1941 PDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPS 2000 + Q F H+ + S + + P++ET S PS Sbjct: 5579 ILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPS 5638 Query: 2001 KPQ---ASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDL---LQECISSAMPKKKKPS 2054 S +P+S PV + L+S+ + + + L E ++S+ P P+ Sbjct: 5639 MTSPSPVSSTSPESIPSSPLPV----TALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPT 5694 Query: 2055 RLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSS 2114 + + K + + ++ S H E +S+ + Sbjct: 5695 QERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGH---------------ESQSSVPAD 5739 Query: 2115 LHQAAAAACLSRQASSDSDSILSLKSGISLGSP-FHLTPDQEEKPFTSNKGPRILKPGEK 2173 H + A + + + S+ S +P F T Q E + G R + E+ Sbjct: 5740 SHTSKATSPMGITFAMGDTSV-------STSTPAFFETRIQTESTSSLIPGLRDTRTSEE 5792 Query: 2174 --STLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISG--QMKQPLQANMPSISRGRT 2229 + ET + SE + +IT S + ISG K + +I+R T Sbjct: 5793 INTVTETSTVLSEVPTTTTTEVSRTEVITS---SRTTISGPDHSKMSPYISTETITRLST 5849 Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289 + G S+ ++ + P+ T + + + ++T S G V P + +T Sbjct: 5850 FPFVTG-----STEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRF-PHSEET 5903 Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349 + + S+K S S PS S P+ P S S + +S + S LP TS Sbjct: 5904 TTMSRSTKGVSWQ----SPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTS 5959 Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409 + GR+ + L + L SS+P + S S G + + Sbjct: 5960 ----------------LLTSGRRKTIDMLDTHSELV--TSSLPSASSFS-GEILTSEAST 6000 Query: 2410 ANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS 2469 + + S ++ + G+ + + + S I PS K+ S +++ +S Sbjct: 6001 NTETIHFSENTAETNMGTTNSMHK----LHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTS 6056 Query: 2470 RPASPTRSQAQTPVLSPSLPDM----------------------SLSTHSSVQAGGWRKL 2507 P SP SP P++ SL + V Sbjct: 6057 TPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYY 6116 Query: 2508 PPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT 2567 P P + P + + SHS SP L I+ T + + S + T Sbjct: 6117 DPTFMPASAQSTKSPDISPEASSSHSNSPP-LTISTHKTIATQTGPSGVT----SLGQLT 6171 Query: 2568 GSSSSILSASSESSEKAKSEDEKHVNSISGTKQS---KENQVSAKGTWRKIKENEFSPTN 2624 +S+I +++ S + + + S+ + K + SA+ + T Sbjct: 6172 LDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTT 6231 Query: 2625 STSQTVSSGATNGAESKTLIYQM-APAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVI 2683 S S S+ + S + + P ++K D+ +E +P++ R+ + Sbjct: 6232 SPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPV-TRSPQNLRNTLATSEATT 6290 Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQN 2743 D + +P+I N A NVG S P N + D+ K T Sbjct: 6291 D--THTMHPSI-----NTAVANVGTTSSP-------NEFYFTVSPDSDPYKAT------- 6329 Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK--SSADSTSAR 2801 + V ++ T+ SIV + SS+ K S T + + + +K SS+D+++ Sbjct: 6330 SAVVITSTSGDSIVSTSMPRSSAMKKIESE--TTFSLIFRLRETSTSQKIGSSSDTSTVF 6387 Query: 2802 PSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831 ++ + + T GT+ P Sbjct: 6388 DKAFTAATTEVSRTELTSSSRTSIQGTEKP 6417 Score = 47.4 bits (111), Expect = 2e-04 Identities = 329/1706 (19%), Positives = 580/1706 (33%), Gaps = 175/1706 (10%) Query: 1200 SSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETI 1259 SS ++S ++SS+S S K + ++HPSS + T ++ ++ Sbjct: 8608 SSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSS----NTPVVNVGTVIYKHLSPSSV 8663 Query: 1260 QTYCVEDTPIC-FSRCSSLSSLSSAEDEIGCNQTTQ-EADSANTLQIAEIKEKIGTRSAE 1317 V P + S+L + S + +T + S+ T + EI T SA Sbjct: 8664 LADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSAT 8723 Query: 1318 DPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKA-----VEFSSGAKSPSKSGAQTPKSP 1372 + + + + TK SR + SL S A E S+ + + T S Sbjct: 8724 ERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSA 8783 Query: 1373 PEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP-SDLPDSPGQTM 1431 +T + +LD+ S + + SG+ +P S P+ Sbjct: 8784 EMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPS 8843 Query: 1432 PPSRSKTPPPPPQTAQTKREVPKNKAPT-AEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490 PS KT PP + + P T +E S P + ++ DT L Sbjct: 8844 RPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLE 8903 Query: 1491 FATESTP-----DGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKES 1545 T S P S ++S + + + + ++ + M + + P+ S Sbjct: 8904 PVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPS 8963 Query: 1546 NENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPV 1605 TI KD++ + EI + S +S P +T++ Sbjct: 8964 KVTSPVVTSSTI---KDIVSTTIPASSEITRIEMES-----TSTLTPTPRETSTSQEIHS 9015 Query: 1606 ARKPSQLPVYKLLPSQNRLQPQKHV-SFTPGDDMPRVYCVEGTPINFSTATSLSDLTIES 1664 A KPS +P YK L S V S + G + + T S S + ES Sbjct: 9016 ATKPSTVP-YKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTES 9074 Query: 1665 PPNELAAGEGVRGGAQSGEFEKRDTIPT--EGRSTDEAQGGKTSSVT---------IPEL 1713 + G G G DT T G + +QG S +T +P L Sbjct: 9075 TEMTITTQTGSPGATSRGTL-TLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWL 9133 Query: 1714 DDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPT 1773 EE + ++S + S + + + SSS P + L K T Sbjct: 9134 SHPSVEEASSASFSLSSPVMTSSS-------PVSSTLPDSIHSSSLPVTSLLTSGLVKTT 9186 Query: 1774 -------SPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDK 1826 P P N T A ++ + E++ N + ++ S V D Sbjct: 9187 ELLGTSSEPETSSPPNLS-STSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADS 9245 Query: 1827 LPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKE 1886 + + S P T + + FS + + + L+ E ++E Sbjct: 9246 VTT---KATSSMGITYPTGDTNVLTSTPAFSDTSRIQT----KSKLSLTPGLMETSISEE 9298 Query: 1887 NKESEAKVTSHTEL-TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGA 1945 + K T + + T ++T+AI+ + P T ++ I Sbjct: 9299 TSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRIST--P 9356 Query: 1946 ATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQAS 2005 T ++ + AI TP ++ +D + T Q + P + Sbjct: 9357 LTRKESTDMAI--TPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSR 9414 Query: 2006 GYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSP 2065 G S+ +P+ +NS SSL S ++S P PS HS Sbjct: 9415 GPEDVSW---PSPLSVEKNSPPSSLVSSSS-------VTSPSPLYSTPS-----GSSHSS 9459 Query: 2066 RNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLS 2125 L + + D+ + L P++ + I + S A + Sbjct: 9460 PVPVTSLFTSIMMKATDM----LDASLEPETTSAPNMNITSDESLAASKATTETEAIHVF 9515 Query: 2126 RQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPR-----ILKPGEK--STLET 2178 ++ S + SP P + P ++ R PG + +E Sbjct: 9516 ENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEI 9575 Query: 2179 KKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM----IHIP 2234 + + S + G++ ++ + + S++E S + + P +SR M IP Sbjct: 9576 ESMSSLTPGLR------ETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIP 9629 Query: 2235 GVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGG 2294 G S+ S + L T + S T TT G + P+ + + G Sbjct: 9630 GPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQ-TGYSLATSQVTLPLGTSMTFLSG 9688 Query: 2295 SSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTA 2354 + S+ S + ++ P S SP + R+ S L+ LP T+S S Sbjct: 9689 THSTMSQGLSHSEMTNLMSRGPESLSWTSP--RFVETTRSSSS----LTSLPLTTSLSPV 9742 Query: 2355 ST---KSSGSGKMSYTS---PGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGN 2408 S+ SS S + TS PG + + L T SS P S S + + Sbjct: 9743 SSTLLDSSPSSPLPVTSLILPGLVKTTEVL--DTSSEPKTSSSPNLSSTSVEIPATSEIM 9800 Query: 2409 GANKKVELSRMSSTKS--SGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLS 2466 +K+ S ++ + S S VL T I PS + ++++ F S Sbjct: 9801 TDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTI-TIPSMGITSAVDDTTVFTSNP 9859 Query: 2467 PSSR----PASPTRSQAQTP---VLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYND 2519 S P PT S TP S S S++ S+V G +P + + + + Sbjct: 9860 AFSETRRIPTEPTFS--LTPGFRETSTSEETTSITETSAVLYG----VPTSATTEVSMTE 9913 Query: 2520 GRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT---GSSSSILSA 2576 + R I S + S I T S S S T +++ ++ S L+ Sbjct: 9914 IMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTL 9973 Query: 2577 SSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS--------TSQ 2628 ++ ++ A++ + + ++ +W+ E + ++S TS Sbjct: 9974 ATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSP 10033 Query: 2629 TVSSGATNG--AESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686 +VSS + S ++ + P + KT D ++ SG S + + Sbjct: 10034 SVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTE-PGTSLSPNLSGTSVEILAASEVTTD 10092 Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPV 2746 +EK +P+ + A NVG T + L S + + + K T PV Sbjct: 10093 TEKIHPS-----SSMAVTNVG-------TTSSGHELYSSVSIHSEPSKAT-------YPV 10133 Query: 2747 PV-SETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQI 2805 S E+SI P + ++ + P + + N S D++S P+ Sbjct: 10134 GTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTN-------MSLDTSSVTPTNT 10186 Query: 2806 PTPVNNNTKKRDSKTDSTESSGTQSP 2831 P+ + + SKTD T S+ T SP Sbjct: 10187 PSSPGSTHLLQSSKTDFTSSAKTSSP 10212 Score = 44.3 bits (103), Expect = 0.002 Identities = 136/638 (21%), Positives = 245/638 (38%), Gaps = 113/638 (17%) Query: 2233 IPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGA--KPSVKSELSPVARQTS 2290 IPG+ + SP+ P+S SPS+ +PR + S+ LS + T+ Sbjct: 2709 IPGITIQGVTESPLH--------PSSTSPSK----IVAPRNTTYEGSITVALSTLPAGTT 2756 Query: 2291 QIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSS 2350 GS S + ++T + L R P ++ G G++ + R+ S Sbjct: 2757 ---GSLVFSQSSENSETTALVDSSAGLERASVMP----LTTGSQGMASSGGI----RSGS 2805 Query: 2351 PSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRS-----ESASKGLNQMN 2405 + TK+ S ++ +PG + +T L+ S+ P+ SA GL Sbjct: 2806 THSTGTKTFSSLPLTM-NPGEVTAMSEITTNR-LTATQSTAPKGIPVKPTSAESGLLTPV 2863 Query: 2406 NGNGANKKVELSRMSSTKSSGSESDR-----SERPVLVRQSTFIKEAPSPTLRRKLEESA 2460 + + + K S ++ + G SE P L +S + P +L + A Sbjct: 2864 SASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLP-TPGQSLNTIPDSDA 2922 Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP-NLSPTIEYND 2519 S S S S P R++ T + S SS Q+ G+ + P + SP++ ++ Sbjct: 2923 STASSSLSKSPEKNPRARMMTSTKAISA--------SSFQSTGFTETPEGSASPSMAGHE 2974 Query: 2520 GR-PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR--RTGSSSSILSA 2576 R P R SES S +++ + S S ST + R+GSSSS +S Sbjct: 2975 PRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISL 3034 Query: 2577 SSESSEKAKS---EDEKHVNSISGTKQSKENQV---------SAKGTWRKIKENEFSPTN 2624 S+E S + + G +++ + + T E P Sbjct: 3035 STEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPEL 3094 Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPV-I 2683 ++SQT++ AE++TL + P+ + T + P+++P + ++P Sbjct: 3095 TSSQTIAEEEGTTAETQTLTF--TPSETPTSLL-------PVSSPTEPTARRKSSPETWA 3145 Query: 2684 DSVSEKANPNIKDSKD----------NQAKQNVGN--------GSVPMRTVGLENRLNSF 2725 S+S A ++ ++ D +QA Q GS P T +++ Sbjct: 3146 SSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTT 3205 Query: 2726 IQVDAPDQKGTEIKPG-----QNNP-------VPVSETNESSIVERTPFSSSSSSKHSSP 2773 +++ + K I P +N+P VP+ T E ++ T S S+S P Sbjct: 3206 LKIMS--SKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLP 3263 Query: 2774 SGTVAARVTP---------FNYNPSPRKSSADSTSARP 2802 +GT + +P + +PSP ++ + S P Sbjct: 3264 TGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTP 3301 Score = 43.5 bits (101), Expect = 0.003 Identities = 143/657 (21%), Positives = 239/657 (36%), Gaps = 104/657 (15%) Query: 2236 VRNSSSSTSP------VSKKGPPLKTPAS----KSPSEGQTATTSPRG-AKPSVKSE--L 2282 V N +++SP VS P K ++ + + +T+ PR A ++SE Sbjct: 6303 VANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTF 6362 Query: 2283 SPVAR----QTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP-IQSPGRNSISPGRNGIS 2337 S + R TSQ GSS S + T A +SR + S R SI Sbjct: 6363 SLIFRLRETSTSQKIGSSSDTSTVFDKAFTA---ATTEVSRTELTSSSRTSIQGTEKPTM 6419 Query: 2338 PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESA 2397 P+ ++ S TKS + T P R SQ LT T ++ S + Sbjct: 6420 SPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSIT--TSQAGTHSAM 6477 Query: 2398 SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLE 2457 + G +Q+ +LS ++S R +I P++ K Sbjct: 6478 THGFSQL----------DLSTLTS-----------------RVPEYISGTSPPSV-EKTS 6509 Query: 2458 ESASFESL----SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSP 2513 S+S SL SPS P + S+ +PV SLP L + + A LPPNL Sbjct: 6510 SSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLA-SVASLPPNLGS 6568 Query: 2514 TIEYNDGRPAKRHDIARSHSESPS-RLPINRSGTWKREHSKHSS----------SLPRVS 2562 T + P DI + PS + + GT E +SS + P V+ Sbjct: 6569 T---SHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVT 6625 Query: 2563 TWR-RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFS 2621 ++ R S+ + SSE + + + GT S++ VS + + K + Sbjct: 6626 SFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGA 6685 Query: 2622 PTNSTSQTVSS------GATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSP 2675 S ++ SS G + ES + ++ P++ + + S + Sbjct: 6686 TETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGI----------TESSNMTI 6735 Query: 2676 TGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKG 2735 T P + S S+ + ++A G+ M T + + + P+ Sbjct: 6736 ITRTGPPLGSTSQGTFTLDTPTTSSRA------GTHSMATQEFPHSEMTTVMNKDPEILS 6789 Query: 2736 TEIKPGQNNPVPVSETNESSIVERTPFSSS-SSSKHSSPSGTVAARVTP--------FNY 2786 I P S S + P SS+ + H++PS + + +TP Sbjct: 6790 WTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPS-PMTSLLTPSLVMTTDTLGT 6848 Query: 2787 NPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV 2843 +P P SS + S+ +I T + +T ++ ST ++ T SG +SV Sbjct: 6849 SPEPTTSSPPNLSSTSHEILT-TDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSV 6904 Score = 43.1 bits (100), Expect = 0.004 Identities = 173/845 (20%), Positives = 303/845 (35%), Gaps = 133/845 (15%) Query: 2074 EDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACL-------SR 2126 E +T +++ P +E L+ + D + I N V+++ A++A L S Sbjct: 4502 EPVTNSPQNLNNPSNEI-LATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSE 4560 Query: 2127 QASSDSDSILSLKSGISLGS---PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIES 2183 +++ S + + G +L S P T D E +P +S R E STL+ + Sbjct: 4561 PSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGR----KENSTLQEMNSTT 4616 Query: 2184 ESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA----NMPSISRGRTMIHIPGVRNS 2239 ES I V K+ S + + P Q+ ++ S++ R P ++ Sbjct: 4617 ESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTIST 4676 Query: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299 +T+ G SK P T+T PSV +E ++ T+ + K Sbjct: 4677 HMTTTQTGSSGA-----TSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDV 4731 Query: 2300 SRSGS--RDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK 2357 S++ +D S +Q P+ P + +P + S P +S + +S TA Sbjct: 4732 SQTNPPFQDEASSPSSQAPVL-VTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTA--- 4787 Query: 2358 SSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417 GK+ T L SS +S S L+ ++ + A +E + Sbjct: 4788 ----GKVD----------------TSLETVTSS---PQSMSNTLDDISVTSAATTDIETT 4824 Query: 2418 RMSSTK---SSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASP 2474 S + G+ E V + SP + E + P S + Sbjct: 4825 HPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTR 4884 Query: 2475 TRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPA----KRHDIAR 2530 T ++ T L+P L + S+S + + T+ Y + A R D+ Sbjct: 4885 TETET-TSSLTPKLRETSISQEITSSTE---------TSTVPYKELTGATTEVSRTDVTS 4934 Query: 2531 SHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590 S S S P T + S +++ R+ST S+ I + A S+D Sbjct: 4935 SSSTS---FPGPDQSTVSLDISTETNT--RLSTSPIMTESAEITITTQTGPHGATSQDTF 4989 Query: 2591 HVNSISGTKQSKENQVSAKG--------TWRKIKEN-------EFSPTNSTSQTVSSGA- 2634 ++ + T Q+ + G +I ++ T+S S +SS A Sbjct: 4990 TMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAM 5049 Query: 2635 -TNGAESKTLIYQM--APAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691 T S TL +P S V+I D R+ P ++ P S S+K Sbjct: 5050 TTPSLISSTLPEDKLSSPMTSLLTSGLVKITDIL----RTRLEPVTSSLPNFSSTSDKIL 5105 Query: 2692 PNIKDSKDNQ---AKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEI------KPGQ 2742 KDSKD + N +V G E+ + + P + P Sbjct: 5106 ATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAP 5165 Query: 2743 NNPVPVSETNESSIVERTP-------FSSSSSSKHSS------------PSGTVAARVTP 2783 + +PV ++E++ ++R P +S+S+ SS P+GT+ V+ Sbjct: 5166 STSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTI-TEVSS 5224 Query: 2784 FNYNPSPRKSSADSTSAR------PSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837 N S + S+ D + +IP ++ K + ++ T + HS Sbjct: 5225 TGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTL 5284 Query: 2838 YLVTS 2842 L TS Sbjct: 5285 PLDTS 5289 Score = 42.4 bits (98), Expect = 0.007 Identities = 140/690 (20%), Positives = 258/690 (37%), Gaps = 127/690 (18%) Query: 2216 PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAK 2275 P+ +P SR + +H+ +S TS + K L + AS P+ G T+ P ++ Sbjct: 6525 PVPTTLPE-SRPSSPVHL-----TSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSE 6578 Query: 2276 ---------PSVKSELSPVARQTSQIGGSSKAPSRS-------------GSRDS--TPSR 2311 PS ++ V TS+ S P+ S RD+ + S Sbjct: 6579 DIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSM 6638 Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPN-------KLSQLPR--TSSPSTASTKSSGSG 2362 P ++R I+ S++ G G S K + L + T + T+ T+ + S Sbjct: 6639 PGSSEITR-IEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSR 6697 Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNN---GNGANKKVELSRM 2419 + S P +++ + + S+ +ES++ + G+ + L Sbjct: 6698 RTSIPGPDHSTESPDISTEV-IPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTP 6756 Query: 2420 SSTKSSGSESDRSERPVLVRQSTFIKEAP---SPTLRRKLEESASFESLSPSSRPASP-- 2474 +++ +G+ S ++ +T + + P S T+ +E+++ SL PS SP Sbjct: 6757 TTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPV 6816 Query: 2475 ---------TRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR 2525 T T +L+PSL + + +S + PPNLS T Sbjct: 6817 SSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPT--TSSPPNLSST----------S 6864 Query: 2526 HDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585 H+I + ++ + ++ S + + + +SS GS SS+L+ SEK K Sbjct: 6865 HEILTTDEDTTAIEAMHPSTSTAATNVETTSS--------GHGSQSSVLA----DSEKTK 6912 Query: 2586 SEDEKHVNSISG-TKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644 + S G T S VS++ T K +E+ +S T +T S + + +++ Sbjct: 6913 ATAPMDTTSTMGHTTVSTSMSVSSETTKIK-RESTYSLTPGLRETSISQNASFSTDTSIV 6971 Query: 2645 YQMAPAVSKTEDVWVRIEDCPINNPRSGRS--PTGNTPPVIDSVSEK------ANPNIKD 2696 P + E + SGR+ P + V+ +S + A+P + + Sbjct: 6972 LSEVPTGTTAEVSRTEVTS-------SGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTE 7024 Query: 2697 SKDNQAKQNVG-NGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS 2755 S + G +GS T+ L+ + S+ Sbjct: 7025 SAEMTIPTQTGPSGSTSQDTLTLD-----------------------TSTTKSQAKTHST 7061 Query: 2756 IVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSAD---STSARPSQIPTPVNNN 2812 + +R P S ++ P G ++ + +P NPS S +TS P PV + Sbjct: 7062 LTQRFPHSEMTTLMSRGP-GDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTIS 7120 Query: 2813 TKKRDSKTDSTESSGTQSPKRHSGSYLVTS 2842 + + T S T + H+ LVTS Sbjct: 7121 SSPLPVTSLLTSSPVTTTDMLHTSPELVTS 7150 Score = 41.2 bits (95), Expect = 0.015 Identities = 142/690 (20%), Positives = 256/690 (37%), Gaps = 94/690 (13%) Query: 2197 SLITGKVRSNSEISGQ-MKQPLQANMPSISRGRTMIH--IP---GVRNSSSSTSPVSKKG 2250 S++ K+ S SGQ + PL +P +R TM + IP + N+ +S V Sbjct: 289 SVLDNKISETSIFSGQSLTSPLSPGVPE-ARASTMPNSAIPFSMTLSNAETSAERVRSTI 347 Query: 2251 PPLKTPASKSPSEGQTATTSPRGAK----PSV---KSELSPVARQTSQIGGSSKAPSRSG 2303 L TP+ + +T T A+ PS K+ S +GG+S + + Sbjct: 348 SSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTT 407 Query: 2304 SRDST----PSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPS----TAS 2355 S +T + + + S++P S P + S++ T P+ T Sbjct: 408 SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLET--SAPGEESEMTATLVPTLGFTTLD 465 Query: 2356 TKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNA----SSIPRSESASKGLNQMNNGNGAN 2411 +K ++S + P R++ T S A S I R+ ++S ++ ++ + Sbjct: 466 SKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSST--SKASSWTSES 523 Query: 2412 KKVELSRMSSTK-SSGSESDRSERPVLVRQ-------------STFIKEAPSPTLRRKLE 2457 + S T+ S S ++ERP S F S T LE Sbjct: 524 TAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLE 583 Query: 2458 ESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAG-GWRKLPPNLSPTIE 2516 E+++ + S+ A PT Q P +S++ SS + G L + + E Sbjct: 584 ETSADTLIGEST--AGPTTHQFAVPT------GISMTGGSSTRGSQGTTHLLTRATASSE 635 Query: 2517 YNDGRPAKRHDIARSHSESPSRLPINRS--GTWKREHSKHSSSLPRVSTWR----RTGSS 2570 + + + S S + S+ S G K ++ SS +P S+ + R G+S Sbjct: 636 TSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTS 695 Query: 2571 SSILSASSESSEKAKSEDEKHVNSIS------GTKQSKENQVSAKGTWRKIKENEFSPTN 2624 + ++ + D IS + E++VSA T+ K T+ Sbjct: 696 LGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKA-----TS 750 Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR-SGRSPTGNTPPVI 2683 S + +T S ++ M + + T VR P+ +P SG G+ + Sbjct: 751 SITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLS 810 Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV-GLENRLNSFIQVDAPDQKGTEIKPGQ 2742 S +PNI + ++ + ++ + +V G++ +S G E + Sbjct: 811 TSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETS 870 Query: 2743 NNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARP 2802 N V ET+ S + RT +S+S P+P + D+ R Sbjct: 871 NPSVSQPETSVSRV--RTTLASTSV--------------------PTPVFPTMDTWPTRS 908 Query: 2803 SQIPTPVNNNTKKRDSKTDSTESSGTQSPK 2832 +Q + + + S T T S+G+ PK Sbjct: 909 AQFSSSHLVSELRATSSTSVTNSTGSALPK 938 Score = 40.0 bits (92), Expect = 0.033 Identities = 143/698 (20%), Positives = 249/698 (35%), Gaps = 106/698 (15%) Query: 2167 ILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISR 2226 ++KPG + L IE+ + + T ++ +S S +M P + N S Sbjct: 1272 VVKPGSYTPLTFPSIET-----------HIHVSTARMAYSSGSSPEMTAPGETNTGSTWD 1320 Query: 2227 GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTA---------TTSPRGAKPS 2277 T I +++SS+ L+T + +E T ++SP P+ Sbjct: 1321 PTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPA 1380 Query: 2278 VKS-ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQ--PLSRPIQSPGRNSIS--PG 2332 K+ ++ ++Q+ + A SG + P P S I S S PG Sbjct: 1381 TKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG 1440 Query: 2333 RNGISPPNKLSQ--LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNL-----TKQTGLS 2385 + P++ + LP + ST+ T+ S + +SP MS + T LS Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500 Query: 2386 KN---ASSIPRSESASK----GLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL- 2437 K+ S+I ++S + G+ + G V ++ +++T +S E + L Sbjct: 1501 KSEADTSAIRNTDSTTLDQHLGIRSLGR-TGDLTTVPITPLTTTWTSVIEHSTQAQDTLS 1559 Query: 2438 -----------VRQSTFIKEAPSPTLRRKLEESASFESLSPSS-----RPASPTRSQA-- 2479 ++ T I + SP+ ++ + S S +P++ T S+ Sbjct: 1560 ATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIE 1619 Query: 2480 QTPVLSPSLPDMSLSTHSSVQAG---GWRKLPPNLSPTIEYNDGRPAKRHDIA------- 2529 P S P M +T S +G G LP S E + +R Sbjct: 1620 TGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAG 1679 Query: 2530 -----------RSHSESPSRLP--INRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSA 2576 RS S+S R+ ++ S T S SS PR++T T SSS+ + Sbjct: 1680 TMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSS-PRLNTQGNTALSSSLEPS 1738 Query: 2577 SSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN 2636 +E S+ + S + S + W K T TS S A Sbjct: 1739 YAEGSQMSTS-----IPLTSSPTTPDVEFIGGSTFWTK-----EVTTVMTSDISKSSART 1788 Query: 2637 GAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKD 2696 + S TL+ + T +R + +P +P+ P I A PN D Sbjct: 1789 ESSSATLMSTALGSTENTGKEKLRTASMDLPSP----TPSMEVTPWISLTLSNA-PNTTD 1843 Query: 2697 SKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSI 2756 S D + + T+ + LN+ + + + G++ + + + + +S+ Sbjct: 1844 SLDLSHGVHTSSAG----TLATDRSLNTGVTRASRLENGSDT---SSKSLSMGNSTHTSM 1896 Query: 2757 VERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSS 2794 T S SSS H P + T P R S Sbjct: 1897 T-YTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAIS 1933 Score = 40.0 bits (92), Expect = 0.033 Identities = 72/347 (20%), Positives = 132/347 (38%), Gaps = 51/347 (14%) Query: 1194 SFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQ---------------- 1237 + + S++S+G + + +S+ + + ++ LHPSS Sbjct: 2685 TLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSI 2744 Query: 1238 --SRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI---GCNQT 1292 + S P V S + E +T + D+ R S + + ++ G Sbjct: 2745 TVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSG 2804 Query: 1293 TQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAV 1352 + + T + G +A +SE+ ++ T+S+ +G + SA + Sbjct: 2805 STHSTGTKTFSSLPLTMNPGEVTA---MSEI-TTNRLTATQSTAPKGIPVKPTSAESGLL 2860 Query: 1353 EFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSG 1412 S + SPSK+ A +PP + ++ L F + V SLD+ +S S+ + Q Sbjct: 2861 TPVSASSSPSKAFASLTTAPPTWGIPQSTLTF-EFSEVPSLDT-KSASLPTPGQ------ 2912 Query: 1413 MVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRES------- 1465 S + +PDS T S SK+P P+ R + KA +A +S Sbjct: 2913 ------SLNTIPDSDASTASSSLSKSPEKNPRA----RMMTSTKAISASSFQSTGFTETP 2962 Query: 1466 -GPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSL 1511 G ++ RV D + S PD SS++++ SL Sbjct: 2963 EGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSL 3009 Score = 39.7 bits (91), Expect = 0.043 Identities = 132/657 (20%), Positives = 251/657 (38%), Gaps = 91/657 (13%) Query: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTAT----TSP-------RGAKPSVKSELSP 2284 + +++ +TS VS + +PS G+T++ TSP R +VKS+++P Sbjct: 3452 ITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRANVSAVKSDIAP 3511 Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQ 2344 A SQ ++ + TP +S I + G NSIS +P +S Sbjct: 3512 TAGHLSQTSSPAEVSILDVTTAPTPG------ISTTITTMGTNSIS--TTTPNPEVGMST 3563 Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE-----SASK 2399 + T + +T + S T+ + ++T ++++ +I ++S Sbjct: 3564 MDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASST 3623 Query: 2400 GLNQMNNGNGANKKVELSRMSSTKSSG---SESDRSERPVLVRQSTFIKEAPSPTLRRKL 2456 L+ M+ +G + S ++ + + +E+ SER + +T P T R Sbjct: 3624 ELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTT--ASTPISTFSRVQ 3681 Query: 2457 EESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIE 2516 S S + +S S T ++ PV S S T + + L +LS T++ Sbjct: 3682 RMSISVPDILSTSWTPSSTEAE-DVPVSMVSTDHASTKTDPNTPLSTF--LFDSLS-TLD 3737 Query: 2517 YNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP--------RVSTWRRTG 2568 ++ GR A + + +P + T + S +S LP V+ Sbjct: 3738 WDTGRSLSS---ATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMAR 3794 Query: 2569 SSSSILSASSESSEKAKSEDEKHVNSISG----TKQSKENQVSAKGTWRKIKENEFSPTN 2624 SS S +S+KA+ + + S +S + K + F Sbjct: 3795 SSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQG 3854 Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS--PTGNTPPV 2682 T+ T + AT+ + ++ + P+ ++ + + I S S T NT + Sbjct: 3855 QTALTTEARATSDSWNEK--EKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDI 3912 Query: 2683 ------IDSVSEKANP--NIKDSKDNQAKQNVGNGSVPMRTVG----LENRLNSFIQVDA 2730 S S K++P I S+ K+ + + + T G E+ +S I + Sbjct: 3913 NLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHS 3972 Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK-HSSPSG--TVAAR-VTPFNY 2786 K T +PV + T E +IV + + S++ + P+ T+ R V+P+ Sbjct: 3973 ASSKLT-------SPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPY-- 4023 Query: 2787 NPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV 2843 D++S + I + + + +T+ T S KR S S+L S+ Sbjct: 4024 --------MDTSSTTQTSIISSPGSTAITKGPRTEITSS------KRISSSFLAQSM 4066 Score = 39.3 bits (90), Expect = 0.056 Identities = 142/708 (20%), Positives = 253/708 (35%), Gaps = 104/708 (14%) Query: 2151 TPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYK----------SLIT 2200 T + + FT ++ P L P T T + +S + V +L+T Sbjct: 3107 TAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVT 3166 Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260 S+ G P A S T PG S++ +S K P + S Sbjct: 3167 TIKMSSQAAQGNSTWPAPAEETGSSPAGTS---PGSPEMSTTLKIMSSKEPSI------S 3217 Query: 2261 PSEGQTATTSPRGAKPS---VKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPL 2317 P T SP + +++ + PV Q++ +G S + S + ++P++ Sbjct: 3218 PEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTK------ 3271 Query: 2318 SRPIQSPGRNSISPGRNGISPP------NKLSQLP---RTSSPSTASTKSSGSGKMSYTS 2368 SP N ++ R +SP N S P R S + +S S T Sbjct: 3272 -----SPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITG 3326 Query: 2369 PGRQMSQQNLTKQTGL-----------SKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417 G+Q S + ++K TG+ + + + S S++ + + + N + + S Sbjct: 3327 TGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKS 3386 Query: 2418 R------MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL--SPSS 2469 + +S+T + + + S + EA S T + S S +L SP Sbjct: 3387 KHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDV 3446 Query: 2470 RPASPTRSQAQTPVLSPSLP--DMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHD 2527 S AQT L SLP D +++ ++ G SP+I G R + Sbjct: 3447 TNTLYITSTAQTTSL-VSLPSGDQGITSLTNPSGGKTSSASSVTSPSI----GLETLRAN 3501 Query: 2528 IARSHSE-SPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS 2586 ++ S+ +P+ +G + S S+ V+T G S++I + + S Sbjct: 3502 VSAVKSDIAPT------AGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTP 3555 Query: 2587 EDEKHVNSISGTKQSKENQVSAK--GTWRKIKENEFSPTNSTSQTVSSGATN--GAESKT 2642 E ++++ T ++ S + TW S S S TV+ +N A S Sbjct: 3556 NPEVGMSTMDSTPATERRTTSTEHPSTWS-------STAASDSWTVTDMTSNLKVARSPG 3608 Query: 2643 LIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQA 2702 I M T + + GR T V S A + + Sbjct: 3609 TISTM-----HTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTL 3663 Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPG--QNNPVPVSETNESSIVERT 2760 + S P+ T R++ + PD T P + VPVS + T Sbjct: 3664 SPSDTTASTPISTFSRVQRMS----ISVPDILSTSWTPSSTEAEDVPVSMVS-------T 3712 Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTP 2808 +S+ + ++ S + ++ +++ SSA +T++ P TP Sbjct: 3713 DHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTP 3760 Score = 38.9 bits (89), Expect = 0.073 Identities = 141/714 (19%), Positives = 257/714 (35%), Gaps = 105/714 (14%) Query: 2124 LSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNK---GPRILKPGEKSTLETKK 2180 ++R + ++ S S KS +S+G+ H + EK S+ P PG ++TL + Sbjct: 1869 VTRASRLENGSDTSSKS-LSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTP 1927 Query: 2181 IESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSS 2240 G + + +L + IS + N M H P + Sbjct: 1928 ---------GNRAISLTLPFSSIPVEEVISTGITSGPDIN------SAPMTHSPITPPTI 1972 Query: 2241 --SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKA 2298 +ST + + PL +S+ S +T SV SP + G S+ + Sbjct: 1973 VWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVN----SVAVSASPTHENSVSSGSSTSS 2028 Query: 2299 PSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKS 2358 P S S +S S +SR RN+I+ ++ + LP T+ PST+ +++ Sbjct: 2029 PYSSASLESLDST-----ISR------RNAITSWLWDLT-----TSLPTTTWPSTSLSEA 2072 Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSR 2418 SG ++P + T + L AS+ SA+K N +G + Sbjct: 2073 LSSGHSGVSNP------SSTTTEFPLFSAAST-----SAAKQRNPETETHGPQ---NTAA 2118 Query: 2419 MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQ 2478 + + S + SE PV ++ E P P + + S S ++ P+ T S Sbjct: 2119 STLNTDASSVTGLSETPV---GASISSEVPLPMAITSRSDVSGLTSES-TANPSLGTASS 2174 Query: 2479 AQTPVL-SPSLPDMSLSTHSSVQAGGWRKLPP-------NLSPTIEYNDGRPAKRHDIAR 2530 A T + + SLP + W P N +I N P +A Sbjct: 2175 AGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVAS 2234 Query: 2531 SHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590 ++P S + S+P VS + S + ++ S EK + + Sbjct: 2235 DVIDTP---------------SDGAESIPTVSF---SPSPDTEVTTISHFPEKT-THSFR 2275 Query: 2591 HVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPA 2650 ++S++ S+ + G W S ST T +S + E +T+ A Sbjct: 2276 TISSLTHELTSRVTPI--PGDW-------MSSAMSTKPTGASPSITLGERRTI----TSA 2322 Query: 2651 VSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGS 2710 T + + + T T ++D+ P+ S + ++ + + Sbjct: 2323 APTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASST 2382 Query: 2711 VPM-RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769 + + +T + S + + + +P VP S T ++ + S++ S Sbjct: 2383 MDVTKTASISPTSISGMTASSSPSLFSSDRP----QVPTSTTETNTATSPSVSSNTYSLD 2438 Query: 2770 HSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ-IPTPVNNNTKKRDSKTDS 2822 S G + + PF SSA +RP + T V+ +T ++ T S Sbjct: 2439 GGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSS 2492 Score = 38.1 bits (87), Expect = 0.12 Identities = 113/567 (19%), Positives = 198/567 (34%), Gaps = 88/567 (15%) Query: 2222 PSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281 P+ R T P +S++++ + ++SP T T+ A + Sbjct: 3568 PATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDS 3627 Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP----GRNGIS 2337 +S + + IG S PS S T + +++ LS P + IS R IS Sbjct: 3628 MSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLS-PSDTTASTPISTFSRVQRMSIS 3686 Query: 2338 PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIP----R 2393 P+ LS TS +++ M T + N T L + S++ R Sbjct: 3687 VPDILS----TSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGR 3742 Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSS------GSESDRSERPVLVRQSTFIKEA 2447 S S++ G +++ L M S +S G + + R S Sbjct: 3743 SLSSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSR 3802 Query: 2448 PSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKL 2507 P PT +K E++++ + S+ P RS A T +P + + ++ Q G L Sbjct: 3803 PDPT-SKKAEQTSTQLPTTTSAHPGQVPRSAATT---LDVIPHTAKTPDATFQRQGQTAL 3858 Query: 2508 PPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT 2567 AR+ S+S W E K + S P ++ + Sbjct: 3859 TTE------------------ARATSDS-----------W-NEKEKSTPSAPWITEMMNS 3888 Query: 2568 GSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTS 2627 S +I +S SS ++ + +N SGT S +W+ +P+ ST+ Sbjct: 3889 VSEDTIKEVTS-SSSVLRTLNTLDINLESGTTSSP--------SWKSSPYERIAPSESTT 3939 Query: 2628 QTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVS 2687 K I+ V T WV S + +T P + S Sbjct: 3940 ------------DKEAIHPSTNTVETTG--WV----------TSSEHASHSTIPAHSASS 3975 Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVP 2747 + +P + S QA ++ + P T NSF+ ++ D + Sbjct: 3976 KLTSPVVTTSTREQAIVSMSTTTWPEST-RARTEPNSFLTIELRD-VSPYMDTSSTTQTS 4033 Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPS 2774 + + S+ + + P + +SSK S S Sbjct: 4034 IISSPGSTAITKGPRTEITSSKRISSS 4060 Score = 37.0 bits (84), Expect = 0.28 Identities = 107/483 (22%), Positives = 174/483 (36%), Gaps = 72/483 (14%) Query: 2239 SSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSP---VARQTSQIGGS 2295 SS S L P + SPS T S + SV S L+P TS G+ Sbjct: 10011 SSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGT 10070 Query: 2296 SKAPSRSG--------SRDSTPSRPAQQPLSRPIQSPGRNS----ISPGRNGISPPNKLS 2343 S +P+ SG S +T + S + + G S + + S P+K + Sbjct: 10071 SLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKAT 10130 Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ-QNLT---KQTGLSKNASSI-PRSESAS 2398 T S S A T S S ++ + G + +LT ++T +S + SS+ P + +S Sbjct: 10131 YPVGTPS-SMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSS 10189 Query: 2399 KGLNQMNNGNGANKKVELSRMSSTKSSG--SESDRSERPV----------LVRQSTFIKE 2446 G + + K + + + T S S +E PV + +ST I Sbjct: 10190 PGSTHLLQSS----KTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITS 10245 Query: 2447 APSPTLRRKLEESASFES--LSPSSRPAS-----PTRSQAQTPVLSPSLPDM---SLSTH 2496 P + ES S L PS+ S P+ S+A T + +P S S Sbjct: 10246 FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPF 10305 Query: 2497 SSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSE---------SPSRLPINRSGTW 2547 S ++G ++ ++ + P + S S S P + Sbjct: 10306 SRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSL 10365 Query: 2548 KREHSKHSSSLPRVSTWR------RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601 E S L VST RT SS + + +ES E V S+S Sbjct: 10366 GTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTR 10425 Query: 2602 KE----------NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651 + N+ + +GT R +K + S + ++ + + +G T E+ T + Sbjct: 10426 TDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTA 10485 Query: 2652 SKT 2654 KT Sbjct: 10486 LKT 10488 Score = 36.6 bits (83), Expect = 0.36 Identities = 90/438 (20%), Positives = 153/438 (34%), Gaps = 63/438 (14%) Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSS-------AQSRSGQPQKAATCKVSSINQE 1257 +S T ++SS+S T + + PS+ S SG +++ S + Sbjct: 8319 TSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKA 8378 Query: 1258 TIQ---TYCVEDTPICFS----------RCSSLSSLSSAEDEIGCNQTTQEADSANTLQI 1304 T TY + +T + S + SSL+S E ++ A +T+ + Sbjct: 8379 TSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTV-L 8437 Query: 1305 AEIK----------EKIGTR----SAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHK 1350 +E+ E I +R S D + P +S T RL S + +ESA Sbjct: 8438 SEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAIT---RLSTSPIMTESAE-S 8493 Query: 1351 AVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIA-----SSV 1405 A+ +G+ + G T + + T S S S + + SR+ S Sbjct: 8494 AITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLP 8553 Query: 1406 QSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPP--------PPQTAQTKR--EVPKN 1455 E S + S + SP+ S T+P S S +P P P +T R P+ Sbjct: 8554 SVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPET 8613 Query: 1456 KAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPF 1515 +P S A R ++ P ++T + S SS L+ L +P Sbjct: 8614 SSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKP- 8672 Query: 1516 IQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEIL 1575 P + GN + S E + ++ S + S + Sbjct: 8673 --------TSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATE 8724 Query: 1576 EECIISAMPTKSSRKAKK 1593 +S MPT ++ K + Sbjct: 8725 RSASLSGMPTGATTKVSR 8742 Score = 35.8 bits (81), Expect = 0.62 Identities = 69/318 (21%), Positives = 120/318 (37%), Gaps = 66/318 (20%) Query: 1187 IPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS----AQSRSGQ 1242 +P K + SS ++S + ++SS+S S ++HPSS A+ R+ Sbjct: 9762 LPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSS 9821 Query: 1243 PQKAATCKVSSINQETIQ------TYCVEDTPI-----------------CFSRCSSLSS 1279 + V + ++ TI T V+DT + FS Sbjct: 9822 SVHESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRE 9881 Query: 1280 LSSAEDEIGCNQTTQEADSANTLQIAEIK--EKIGTRSAEDPVSEVPAVSQHPRTK-SSR 1336 S++E+ +T+ T E+ E + + P S+ +S T+ +R Sbjct: 9882 TSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITR 9941 Query: 1337 LQGSSLSSESARHKAV--EFSSGAKSPSKSGAQTPKSP---------------------- 1372 L SS+ SES + + S GA + S T +P Sbjct: 9942 LSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMS 10001 Query: 1373 --PEHYVQETPLMFSRCTSVSSLDSF---ESRSIASSV-QSEPCSG------MVSGIISP 1420 PE+ ++ L + +S SSL S S S++S++ QS P S + G++ Sbjct: 10002 RSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKT 10061 Query: 1421 SDLPDSPGQTMPPSRSKT 1438 +D PG ++ P+ S T Sbjct: 10062 TDTSTEPGTSLSPNLSGT 10079 Score = 34.3 bits (77), Expect = 1.8 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 7/111 (6%) Query: 1324 PAVSQHPRTKSSRLQGSSLSSESA-----RHKAVEFSSGAKSPSKSGAQTPKSP-PEHYV 1377 PA + P ++ + GSS +SE++ KA+ S + SGA S PE + Sbjct: 2538 PATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLL 2597 Query: 1378 QETPLMFSRCTS-VSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSP 1427 T + TS + D+ ++++ P +G +SG P+ LPD+P Sbjct: 2598 VVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTP 2648 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 55.5 bits (132), Expect = 8e-07 Identities = 171/898 (19%), Positives = 324/898 (36%), Gaps = 162/898 (18%) Query: 1180 SLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQN-QLHPSSAQS 1238 S K ++ + S + + SSSG +S + S N S SS K Q+ H S S Sbjct: 120 SQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSS 179 Query: 1239 RSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADS 1298 G+PQ VSS+N S S S D Sbjct: 180 SPGKPQA-----VSSLN--------------------SSHSRSHGNDH------------ 202 Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358 KE ++S DP + + S+ P + S S ++ ++ A Sbjct: 203 -------HSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTA 255 Query: 1359 KSPSKSGAQT--PKSPPEHYVQETPLMFSRCTSVSSLD-SFESRSIASSVQSEPCSGMVS 1415 G ++ PK EHY + S S++ L S ++ + S+P S Sbjct: 256 YVRPMDGQESMEPKLSSEHYSSQ-----SHGNSMTELKPSSKAHLTKLKIPSQPLDASAS 310 Query: 1416 GIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQT--KREVPKNKAPTAEKRESGPKQAAVN 1473 G +S D + + + PPP T K E K PT E ++S Sbjct: 311 GDVSCVD-------EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSN------F 357 Query: 1474 AAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDN 1533 ++ + P + H + D SSS ++ ++D + + MP + Sbjct: 358 GTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSS------EDSDGEQDCD-KTMP--RSTPG 408 Query: 1534 GNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKK 1593 N S E +N ++ SE DS+ + + S +A + Sbjct: 409 SNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESES-------------SSSDSEANE 455 Query: 1594 PAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHV--SFTPGDDMPRVYCVEGTPINF 1651 P+Q+AS P P QL + + +++ P V + + +GT ++ Sbjct: 456 PSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSY 515 Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSV-TI 1710 + + + + +P + + ++ G++SG GR AQ T+ T+ Sbjct: 516 TDTSGPKETSSATPGRD---SKTIQKGSESGR----------GRQKSPAQSDSTTQRRTV 562 Query: 1711 PELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKK 1770 + KAE+ AE + K +S P + M + +A+ + N KK+ Sbjct: 563 GKKQPKKAEKA--AAEEPRGGL-KIESETPVDLASSMPSSRHKAATKGSRKPNI---KKE 616 Query: 1771 KPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVF--NDKLP 1828 +SP +P + +Y++ + + S+ + + SD+ +S+ + + + +++ P Sbjct: 617 SKSSP-RPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTP 675 Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDD------DVDLS------- 1875 V +F ++P+E + LS L DD +DL+ Sbjct: 676 VKPSSVEEEDSFFRQRMFSPME-------EKELLSPLSEPDDRYPLIVKIDLNLLTRIPG 728 Query: 1876 -------REKAELRKAKENKESEAKVTSHTELTSNQQSANKTQ-----AIAKQP----IN 1919 K E + E EA+ + ++++ + +K + + +K+P N Sbjct: 729 KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN 788 Query: 1920 RGQPKPILQKQSTFPQSSKD---IPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDID 1976 KP ++S+ ++K+ +P K + S +SSL S S+ + Sbjct: 789 SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSN 848 Query: 1977 QENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDS 2034 +E + ++ ++G+ S S V++ S N S+ ++DS Sbjct: 849 KETSGSSKNSSSTSKQKKTEGKTSS--------SSKEVKEKAPSSSSNCPPSAPTLDS 898 Score = 47.4 bits (111), Expect = 2e-04 Identities = 145/692 (20%), Positives = 245/692 (35%), Gaps = 115/692 (16%) Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300 SS ++ PP S S + TA P + S++ +LS +SQ G+S Sbjct: 229 SSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSS-EHYSSQSHGNSMTEL 287 Query: 2301 RSGSRD-----STPSRPAQQPLSRPIQSPGR------NSISPGRNGISPPNKL--SQLPR 2347 + S+ PS+P S + +S P I P K S+ P Sbjct: 288 KPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPF 347 Query: 2348 TSSPSTASTKSSGSGKM---SYTSPGRQMSQQNLTKQTGLSKNASS---------IPRSE 2395 + S S +G K S TS G Q S+ L LS + S +PRS Sbjct: 348 PTKESQQSNFGTGEQKRYNPSKTSNGHQ-SKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406 Query: 2396 SASKGLNQMNNGNGANKKVE--LSRMSSTKSSGSESD--------RSERPVLVRQSTFIK 2445 S +N GA+ + S S SSGS+S+ + P QS + Sbjct: 407 PGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEP---SQSASPE 463 Query: 2446 EAPSPTLR------------RKLEESASFESLSPSSR-------------PASPTRSQAQ 2480 P PT + K+ ++S +S PSS+ + T + Sbjct: 464 PEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKE 523 Query: 2481 TPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGR--PAKRHDIA--------R 2530 T +P ++ S G + + S T G+ P K A + Sbjct: 524 TSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLK 583 Query: 2531 SHSESP----SRLPINR-----SGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581 SE+P S +P +R G+ K K S S PR + ++ S+S +SS Sbjct: 584 IESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS------KSS 637 Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG-----ATN 2636 +K++ E +S S + +S+ S++ K E+ +P +S + Sbjct: 638 QKSREIIETDTSS-SDSDESESLPPSSQTP--KYPESNRTPVKPSSVEEEDSFFRQRMFS 694 Query: 2637 GAESKTLIYQMA------PAVSKTE-DVWVRIEDCPINNPRSGRSPTGNTPP-------- 2681 E K L+ ++ P + K + ++ RI P + N P Sbjct: 695 PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754 Query: 2682 -VIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP 2740 + VS K K+ DN+A ++ + + G + N + K ++ P Sbjct: 755 QASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA-AKEKDLLP 813 Query: 2741 GQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800 PVP + + S SSS K SS S + + + + S +K + TS+ Sbjct: 814 SPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSS 873 Query: 2801 RPSQIPTPVNNNTKKRDSKTDSTESSGTQSPK 2832 ++ +++ + +SS + K Sbjct: 874 SSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905 Score = 40.8 bits (94), Expect = 0.019 Identities = 99/503 (19%), Positives = 174/503 (34%), Gaps = 58/503 (11%) Query: 766 AQHLSETFDNI--DNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTG--NMTV 821 + H SE DN D+ S S S +S + N + S N Sbjct: 414 SHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ 473 Query: 822 LSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQIS 881 L +LN V P S S+DS+ + R G GN + T P +S S Sbjct: 474 LDNWLNK-VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETS------S 526 Query: 882 TTAAQIAKVMEEVSAIHTSQEDR--SSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTK 939 T + +K +++ S ++ S STT+ V ++ +AA Sbjct: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586 Query: 940 SENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQ 999 + SMP SS +G KP+I+ S+ + Sbjct: 587 ETPVDLASSMP-----------------SSRHKAATKGSRKPNIKKESKSSPRPTAEKKK 629 Query: 1000 YPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDE 1059 Y + S ++ + D+ + SL S + + P N +P + E++ Sbjct: 630 YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT----PKYPESNRTPVKPSSVEEED 685 Query: 1060 IKQSEQRQSRNQSTTYPVYTESTDDKH---LKFQPHFGQQECVSPYRSRGANGSETNRVG 1116 ++ S + DD++ +K + + PY+ E V Sbjct: 686 SFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745 Query: 1117 SNHG------INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNY--SIKYN- 1167 H ++ VS ++ EDD + S++ E+++ +P++ S K + Sbjct: 746 EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA 805 Query: 1168 -EEKRHVDQPIDY-----------SLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSS 1215 +EK + P S K SS K S + +K +SG S + S Sbjct: 806 AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865 Query: 1216 ENTSTPSSNAKRQNQLHPSSAQS 1238 + SS++K + PSS+ + Sbjct: 866 KTEGKTSSSSKEVKEKAPSSSSN 888 Score = 37.0 bits (84), Expect = 0.28 Identities = 46/193 (23%), Positives = 69/193 (35%), Gaps = 21/193 (10%) Query: 2157 KPFTSNKGPRILKPG--EKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMK 2214 KP+ + P+ K EK T E +K SE KG +K + + + K Sbjct: 729 KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK--------HKNEDDNRASESK 780 Query: 2215 QPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGA 2274 +P + S H P N SS +K+ L +PA PS+ R Sbjct: 781 KPKTEDKNSAG------HKPS-SNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKR 833 Query: 2275 KPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN 2334 S S L + + GSSK S + + T + + ++P +S P Sbjct: 834 TISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPP-- 891 Query: 2335 GISPPNKLSQLPR 2347 S P S PR Sbjct: 892 --SAPTLDSSKPR 902 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.122 0.337 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 112,480,473 Number of Sequences: 37866 Number of extensions: 5634385 Number of successful extensions: 44545 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 151 Number of HSP's successfully gapped in prelim test: 1474 Number of HSP's that attempted gapping in prelim test: 30322 Number of HSP's gapped (non-prelim): 13502 length of query: 2843 length of database: 18,247,518 effective HSP length: 120 effective length of query: 2723 effective length of database: 13,703,598 effective search space: 37314897354 effective search space used: 37314897354 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.