Guide to the Human Genome
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Search of human proteins with 52138513

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52138513 SIN3 homolog B, transcription regulator [Homo
sapiens]
         (1162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens]   2359   0.0  
gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]        1148   0.0  
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]       1148   0.0  
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]       1148   0.0  
gi|18426913 drebrin 1 isoform b [Homo sapiens]                         43   0.002
gi|18426915 drebrin 1 isoform a [Homo sapiens]                         43   0.002
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  40   0.010
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      39   0.029
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    39   0.038
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    39   0.038
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              38   0.064
gi|222537714 taxilin beta [Homo sapiens]                               37   0.11 
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     37   0.11 
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    37   0.11 
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      37   0.14 
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      37   0.14 
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       37   0.14 
gi|62422577 neurobeachin [Homo sapiens]                                37   0.14 
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    37   0.14 
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          36   0.19 
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]      36   0.19 
gi|33286446 opioid growth factor receptor [Homo sapiens]               36   0.24 
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    36   0.24 
gi|239753043 PREDICTED: hypothetical protein [Homo sapiens]            35   0.32 
gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]           35   0.32 
gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]           35   0.32 
gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]           35   0.32 
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    35   0.32 
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    35   0.32 
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    35   0.32 

>gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens]
          Length = 1162

 Score = 2359 bits (6114), Expect = 0.0
 Identities = 1162/1162 (100%), Positives = 1162/1162 (100%)

Query: 1    MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 60
            MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA
Sbjct: 1    MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 60

Query: 61   TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 120
            TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI
Sbjct: 61   TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 120

Query: 121  QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 180
            QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP
Sbjct: 121  QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 180

Query: 181  EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 240
            EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR
Sbjct: 181  EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 240

Query: 241  SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 300
            SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG
Sbjct: 241  SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 300

Query: 301  KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 360
            KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA
Sbjct: 301  KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 360

Query: 361  QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 420
            QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC
Sbjct: 361  QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 420

Query: 421  KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY 480
            KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY
Sbjct: 421  KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY 480

Query: 481  EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ 540
            EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ
Sbjct: 481  EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ 540

Query: 541  RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY 600
            RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY
Sbjct: 541  RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY 600

Query: 601  LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ 660
            LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ
Sbjct: 601  LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ 660

Query: 661  ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP 720
            ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP
Sbjct: 661  ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP 720

Query: 721  QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN 780
            QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN
Sbjct: 721  QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN 780

Query: 781  WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS 840
            WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS
Sbjct: 781  WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS 840

Query: 841  EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL 900
            EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL
Sbjct: 841  EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL 900

Query: 901  VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR 960
            VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR
Sbjct: 901  VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR 960

Query: 961  KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK 1020
            KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK
Sbjct: 961  KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK 1020

Query: 1021 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT 1080
            KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT
Sbjct: 1021 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT 1080

Query: 1081 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET 1140
            LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET
Sbjct: 1081 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET 1140

Query: 1141 VHVHGLPVTRYRVQYSRRPASP 1162
            VHVHGLPVTRYRVQYSRRPASP
Sbjct: 1141 VHVHGLPVTRYRVQYSRRPASP 1162


>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 1148 bits (2969), Expect = 0.0
 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%)

Query: 41   VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100
            VEDAL+YLDQVK++FGS P  YN FL+IMKEFKSQSIDTPGVI RVSQLF  HPDLI+GF
Sbjct: 123  VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182

Query: 101  NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140
            N FLP GY+I++  N  +N+ +P                      SQ ++ +    A+  
Sbjct: 183  NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242

Query: 141  KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160
             Q  P K  KP           Q P                               +  V
Sbjct: 243  PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302

Query: 161  EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217
            EFN+AI+YVNKIK RF   P+IY++FLEILHTYQKEQ N +   G     ++E+EV+ +V
Sbjct: 303  EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362

Query: 218  ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274
            A LF+ QEDLLSEFGQFLP+A  S+       E     +N+H    K P+ + K  RPS 
Sbjct: 363  ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422

Query: 275  L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326
                        + P KKK KL   KD S+A   K+G   E  FFDKVR+ L+S E YEN
Sbjct: 423  NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482

Query: 327  FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385
            FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF  FK+FLG KE +       +R+ +GI
Sbjct: 483  FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542

Query: 386  SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445
            + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE                       
Sbjct: 543  AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579

Query: 446  CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505
                     VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI
Sbjct: 580  ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630

Query: 506  RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565
            RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP  
Sbjct: 631  RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690

Query: 566  AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625
            AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL
Sbjct: 691  AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750

Query: 626  NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685
            NEIES+YDE QEQ +E  +     PHL   YED+QILEDAAALI ++VKRQ  IQKED+ 
Sbjct: 751  NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810

Query: 686  TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745
             I Q++H F+P L F+Q+ DL   EE  +E+ D       + +   K   G   SPP+ K
Sbjct: 811  KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865

Query: 746  GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805
              F +  A +          + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I  QA++Q
Sbjct: 866  LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916

Query: 806  LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865
            + E   E+E E+ +   +R+K   PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID 
Sbjct: 917  IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976

Query: 866  TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925
            +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E   GA GG 
Sbjct: 977  SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036

Query: 926  LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985
            L+++  R+  E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE  ++DPVE +
Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096

Query: 986  HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045
              + YVE+Y+ ++  S    E    KPVFL RNL++ R+  +  + +   G+  +S K +
Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156

Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105
              V+S   ++CRFKL+++KMV+++ SEDYMYRR  L RA Q    V  R HQ F+ W  +
Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216

Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155
            W +++V  E A+    WLMGE  E +VPC T C+T  +H + + +YRV+Y
Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%)

Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176
           + +  +SH+H    +    QV      P  P+       +   ++  +A+SY++++K +F
Sbjct: 78  IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137

Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236
              P++Y  FL+I+  ++ + ++T G          V + V+ LF+G  DL+  F  FLP
Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187

Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282
              +       +     P ++H +    H   P+       PS     SAPA
Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%)

Query: 38  PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84
           PV    A+ Y++++K RF   P  Y  FLEI+  ++ +  +        TP      V  
Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 85  RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144
           +V++LF    DL+  F  FLP         N  + +      + +S  +  G    K Q+
Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413

Query: 145 PYKEDKP 151
             K  +P
Sbjct: 414 NNKPQRP 420


>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 1148 bits (2969), Expect = 0.0
 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%)

Query: 41   VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100
            VEDAL+YLDQVK++FGS P  YN FL+IMKEFKSQSIDTPGVI RVSQLF  HPDLI+GF
Sbjct: 123  VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182

Query: 101  NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140
            N FLP GY+I++  N  +N+ +P                      SQ ++ +    A+  
Sbjct: 183  NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242

Query: 141  KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160
             Q  P K  KP           Q P                               +  V
Sbjct: 243  PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302

Query: 161  EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217
            EFN+AI+YVNKIK RF   P+IY++FLEILHTYQKEQ N +   G     ++E+EV+ +V
Sbjct: 303  EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362

Query: 218  ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274
            A LF+ QEDLLSEFGQFLP+A  S+       E     +N+H    K P+ + K  RPS 
Sbjct: 363  ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422

Query: 275  L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326
                        + P KKK KL   KD S+A   K+G   E  FFDKVR+ L+S E YEN
Sbjct: 423  NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482

Query: 327  FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385
            FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF  FK+FLG KE +       +R+ +GI
Sbjct: 483  FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542

Query: 386  SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445
            + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE                       
Sbjct: 543  AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579

Query: 446  CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505
                     VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI
Sbjct: 580  ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630

Query: 506  RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565
            RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP  
Sbjct: 631  RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690

Query: 566  AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625
            AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL
Sbjct: 691  AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750

Query: 626  NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685
            NEIES+YDE QEQ +E  +     PHL   YED+QILEDAAALI ++VKRQ  IQKED+ 
Sbjct: 751  NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810

Query: 686  TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745
             I Q++H F+P L F+Q+ DL   EE  +E+ D       + +   K   G   SPP+ K
Sbjct: 811  KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865

Query: 746  GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805
              F +  A +          + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I  QA++Q
Sbjct: 866  LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916

Query: 806  LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865
            + E   E+E E+ +   +R+K   PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID 
Sbjct: 917  IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976

Query: 866  TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925
            +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E   GA GG 
Sbjct: 977  SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036

Query: 926  LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985
            L+++  R+  E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE  ++DPVE +
Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096

Query: 986  HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045
              + YVE+Y+ ++  S    E    KPVFL RNL++ R+  +  + +   G+  +S K +
Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156

Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105
              V+S   ++CRFKL+++KMV+++ SEDYMYRR  L RA Q    V  R HQ F+ W  +
Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216

Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155
            W +++V  E A+    WLMGE  E +VPC T C+T  +H + + +YRV+Y
Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%)

Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176
           + +  +SH+H    +    QV      P  P+       +   ++  +A+SY++++K +F
Sbjct: 78  IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137

Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236
              P++Y  FL+I+  ++ + ++T G          V + V+ LF+G  DL+  F  FLP
Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187

Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282
              +       +     P ++H +    H   P+       PS     SAPA
Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%)

Query: 38  PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84
           PV    A+ Y++++K RF   P  Y  FLEI+  ++ +  +        TP      V  
Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 85  RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144
           +V++LF    DL+  F  FLP         N  + +      + +S  +  G    K Q+
Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413

Query: 145 PYKEDKP 151
             K  +P
Sbjct: 414 NNKPQRP 420


>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 1148 bits (2969), Expect = 0.0
 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%)

Query: 41   VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100
            VEDAL+YLDQVK++FGS P  YN FL+IMKEFKSQSIDTPGVI RVSQLF  HPDLI+GF
Sbjct: 123  VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182

Query: 101  NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140
            N FLP GY+I++  N  +N+ +P                      SQ ++ +    A+  
Sbjct: 183  NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242

Query: 141  KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160
             Q  P K  KP           Q P                               +  V
Sbjct: 243  PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302

Query: 161  EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217
            EFN+AI+YVNKIK RF   P+IY++FLEILHTYQKEQ N +   G     ++E+EV+ +V
Sbjct: 303  EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362

Query: 218  ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274
            A LF+ QEDLLSEFGQFLP+A  S+       E     +N+H    K P+ + K  RPS 
Sbjct: 363  ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422

Query: 275  L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326
                        + P KKK KL   KD S+A   K+G   E  FFDKVR+ L+S E YEN
Sbjct: 423  NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482

Query: 327  FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385
            FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF  FK+FLG KE +       +R+ +GI
Sbjct: 483  FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542

Query: 386  SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445
            + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE                       
Sbjct: 543  AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579

Query: 446  CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505
                     VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI
Sbjct: 580  ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630

Query: 506  RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565
            RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP  
Sbjct: 631  RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690

Query: 566  AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625
            AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL
Sbjct: 691  AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750

Query: 626  NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685
            NEIES+YDE QEQ +E  +     PHL   YED+QILEDAAALI ++VKRQ  IQKED+ 
Sbjct: 751  NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810

Query: 686  TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745
             I Q++H F+P L F+Q+ DL   EE  +E+ D       + +   K   G   SPP+ K
Sbjct: 811  KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865

Query: 746  GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805
              F +  A +          + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I  QA++Q
Sbjct: 866  LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916

Query: 806  LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865
            + E   E+E E+ +   +R+K   PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID 
Sbjct: 917  IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976

Query: 866  TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925
            +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E   GA GG 
Sbjct: 977  SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036

Query: 926  LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985
            L+++  R+  E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE  ++DPVE +
Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096

Query: 986  HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045
              + YVE+Y+ ++  S    E    KPVFL RNL++ R+  +  + +   G+  +S K +
Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156

Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105
              V+S   ++CRFKL+++KMV+++ SEDYMYRR  L RA Q    V  R HQ F+ W  +
Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216

Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155
            W +++V  E A+    WLMGE  E +VPC T C+T  +H + + +YRV+Y
Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%)

Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176
           + +  +SH+H    +    QV      P  P+       +   ++  +A+SY++++K +F
Sbjct: 78  IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137

Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236
              P++Y  FL+I+  ++ + ++T G          V + V+ LF+G  DL+  F  FLP
Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187

Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282
              +       +     P ++H +    H   P+       PS     SAPA
Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%)

Query: 38  PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84
           PV    A+ Y++++K RF   P  Y  FLEI+  ++ +  +        TP      V  
Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 85  RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144
           +V++LF    DL+  F  FLP         N  + +      + +S  +  G    K Q+
Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413

Query: 145 PYKEDKP 151
             K  +P
Sbjct: 414 NNKPQRP 420


>gi|18426913 drebrin 1 isoform b [Homo sapiens]
          Length = 651

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 51/211 (24%)

Query: 572 KRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNF---KQNDTKALRSKSLLNEI 628
           +R KA +E  R  Q+   +  +EQ E+        Q +     KQ   +A  +K  L E 
Sbjct: 197 ERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE- 255

Query: 629 ESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIH 688
           +S++ +H+++  E     S              +E+AAA+I+         Q+ D     
Sbjct: 256 QSIFGDHRDEEEETHMKKSESE-----------VEEAAAIIA---------QRPDN---- 291

Query: 689 QLLHQFVPSLFFSQQLDLGASEESADEDRDSP----QGQTTDPSERKKPAPGPHSSPPEE 744
                  P  FF QQ +  AS  +   D  SP     G   D   R  P P P  SP + 
Sbjct: 292 -------PREFFKQQ-ERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDS 343

Query: 745 -----------KGAFGDAPATEQPPLPPPAP 764
                      + A  +  +++ PPLPPP P
Sbjct: 344 STASTPVAEQIERALDEVTSSQPPPLPPPPP 374


>gi|18426915 drebrin 1 isoform a [Homo sapiens]
          Length = 649

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 51/211 (24%)

Query: 572 KRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNF---KQNDTKALRSKSLLNEI 628
           +R KA +E  R  Q+   +  +EQ E+        Q +     KQ   +A  +K  L E 
Sbjct: 195 ERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE- 253

Query: 629 ESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIH 688
           +S++ +H+++  E     S              +E+AAA+I+         Q+ D     
Sbjct: 254 QSIFGDHRDEEEETHMKKSESE-----------VEEAAAIIA---------QRPDN---- 289

Query: 689 QLLHQFVPSLFFSQQLDLGASEESADEDRDSP----QGQTTDPSERKKPAPGPHSSPPEE 744
                  P  FF QQ +  AS  +   D  SP     G   D   R  P P P  SP + 
Sbjct: 290 -------PREFFKQQ-ERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDS 341

Query: 745 -----------KGAFGDAPATEQPPLPPPAP 764
                      + A  +  +++ PPLPPP P
Sbjct: 342 STASTPVAEQIERALDEVTSSQPPPLPPPPP 372


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.4 bits (93), Expect = 0.010
 Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 721  QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSL 774
            QG  T P+ +K P PGP S  PE K A G  P     P PPP   KP+  V  L
Sbjct: 1240 QGSPT-PTSKKVPLPGPGS--PEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGL 1290


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 52/232 (22%), Positives = 93/232 (40%), Gaps = 36/232 (15%)

Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613
           ++ +  +++P   +  +L + + + EE +E ++   +  R + E+  L+  + Q    + 
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430

Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673
            D +ALR +    + E   +  ++Q  E R +   +         RQ+ ++ A L S   
Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481

Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724
           ++Q   +QK+ Q    QLL      L+       G     AD        E+R     Q 
Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533

Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDD 770
             P  + KP       P P +SP    G     P  ++P  P   PHK L D
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSLQD 584


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 38.5 bits (88), Expect = 0.038
 Identities = 34/178 (19%), Positives = 72/178 (40%), Gaps = 8/178 (4%)

Query: 466 WSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEK 525
           W+  +     K    EE++   E++  E +  +      IR  E   ++   M  E +EK
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350

Query: 526 FRLDDSLGGTSEVIQRRAIYRIY--GDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWRE 583
            R  + +    E   RR    ++   +K  E+ E + +          ++ + K  E  +
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410

Query: 584 AQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSE 641
            Q+   K+WR++      + +  Q    ++ + K  R +  ++E E + +E + Q  E
Sbjct: 411 RQEQEAKMWRQE------EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 38.5 bits (88), Expect = 0.038
 Identities = 34/178 (19%), Positives = 72/178 (40%), Gaps = 8/178 (4%)

Query: 466 WSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEK 525
           W+  +     K    EE++   E++  E +  +      IR  E   ++   M  E +EK
Sbjct: 352 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411

Query: 526 FRLDDSLGGTSEVIQRRAIYRIY--GDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWRE 583
            R  + +    E   RR    ++   +K  E+ E + +          ++ + K  E  +
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471

Query: 584 AQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSE 641
            Q+   K+WR++      + +  Q    ++ + K  R +  ++E E + +E + Q  E
Sbjct: 472 RQEQEAKMWRQE------EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 37.7 bits (86), Expect = 0.064
 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 12/81 (14%)

Query: 694 FVPSLFFSQQLDLGASEESADE---DRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGD 750
           +   L FS + D   S+E   E   D  S  G+   P    K    P+S PP  K A+ +
Sbjct: 335 YTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAE 394

Query: 751 ---------APATEQPPLPPP 762
                     P   +PPLPPP
Sbjct: 395 TSRPPETEPGPPAPKPPLPPP 415



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 19/54 (35%), Positives = 22/54 (40%)

Query: 711 ESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAP 764
           ++A  +   P      P   K P P PH  P    G  GD P    PP  PPAP
Sbjct: 389 KTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP 442



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 23/85 (27%)

Query: 700 FSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPL 759
           ++++L     E+  D D +  +G       R   +      PPE  G  G++P +E PP 
Sbjct: 335 YTEKLKFSDEEDGRDSDEEGAEGH------RDSQSASGEERPPEADGKKGNSPNSE-PPT 387

Query: 760 P----------------PPAPHKPL 768
           P                PPAP  PL
Sbjct: 388 PKTAWAETSRPPETEPGPPAPKPPL 412


>gi|222537714 taxilin beta [Homo sapiens]
          Length = 684

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 42/177 (23%), Positives = 73/177 (41%), Gaps = 17/177 (9%)

Query: 592 WREQYE---KAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSS 648
           W+ ++E   KA L  ++ +A+  K+ +   ++   L N   ++ +E  E H + R A  S
Sbjct: 405 WKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEIS 464

Query: 649 EP-----HLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLH--QFVPSLFFS 701
           E      H      +  +  D           Q A++  +  T   ++H  +  P     
Sbjct: 465 EKDDQSQHNSDEEPESNVSVDQEIDAEEVNSVQTAVK--NLATAFMIIHHPESTPHQSKE 522

Query: 702 QQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPP 758
            Q ++G+S+ESAD     P+     PS R   +P P  +P  E     DA    +PP
Sbjct: 523 TQPEIGSSQESADAALKEPEQPPLIPS-RDSESPLPPLTPQAEAEGGSDA----EPP 574


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 17/30 (56%), Positives = 20/30 (66%)

Query: 4   AGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33
           +GGGSG  G GG AG G  G+  G SG+AG
Sbjct: 489 SGGGSGSGGGGGGAGGGGGGSSGGGSGTAG 518



 Score = 34.7 bits (78), Expect = 0.54
 Identities = 17/31 (54%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 3   HAGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33
           H GGGSG  GAGG +G G SG+  G  G+ G
Sbjct: 475 HRGGGSGSGGAGGGSGGG-SGSGGGGGGAGG 504



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 15/30 (50%), Positives = 18/30 (60%)

Query: 4   AGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33
           +GG  GGSG G  +G G  GA  G  GS+G
Sbjct: 482 SGGAGGGSGGGSGSGGGGGGAGGGGGGSSG 511


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
            [Homo sapiens]
          Length = 1490

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 34/160 (21%), Positives = 58/160 (36%), Gaps = 18/160 (11%)

Query: 607  QAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAA 666
            Q +N   N     + ++L   I ++ +   +Q      AP           +  + E  +
Sbjct: 1136 QLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAP-----------EESLKEAPS 1184

Query: 667  ALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTD 726
            A +      Q  ++        Q +   + S     Q   G+ EE+  +    PQG    
Sbjct: 1185 APVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRT 1244

Query: 727  PSERKKPAPG--PHSSPPEEKGAFGDAPATEQPPLPPPAP 764
            P+  ++ A    PH  PPE++      P    PP PPP P
Sbjct: 1245 PTMPQEEAAACPPHILPPEKR-----PPEPPGPPPPPPPP 1279


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%)

Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613
           ++ +  +++P   +  +L + + + EE +E ++   +  R + E+  L+  + Q    + 
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430

Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673
            D +ALR +    + E   +  ++Q  E R +   +         RQ+ ++ A L S   
Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481

Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724
           ++Q   +QK+ Q    QLL      L+       G     AD        E+R     Q 
Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533

Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768
             P  + KP       P P +SP    G     P  ++P  P   PHK L
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%)

Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613
           ++ +  +++P   +  +L + + + EE +E ++   +  R + E+  L+  + Q    + 
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430

Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673
            D +ALR +    + E   +  ++Q  E R +   +         RQ+ ++ A L S   
Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481

Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724
           ++Q   +QK+ Q    QLL      L+       G     AD        E+R     Q 
Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533

Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768
             P  + KP       P P +SP    G     P  ++P  P   PHK L
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%)

Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613
           ++ +  +++P   +  +L + + + EE +E ++   +  R + E+  L+  + Q    + 
Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430

Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673
            D +ALR +    + E   +  ++Q  E R +   +         RQ+ ++ A L S   
Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481

Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724
           ++Q   +QK+ Q    QLL      L+       G     AD        E+R     Q 
Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533

Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768
             P  + KP       P P +SP    G     P  ++P  P   PHK L
Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582


>gi|62422577 neurobeachin [Homo sapiens]
          Length = 2946

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 4  AGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRF 55
          AGGG GGSG GG  G G+   R G SGS G   LP  + +    +  ++++F
Sbjct: 25 AGGGGGGSGGGGTGGSGMGELR-GASGS-GSVMLPAGMINPSVPIRNIRMKF 74


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 19/149 (12%)

Query: 707 GASEESADEDRDSPQGQTTDP-SERKKPAPGPHSSPPEEKGAFGDAPA-----TEQP-PL 759
           G  ++S  + R S + ++  P S    PAP P  +PP+++    + P      T  P P 
Sbjct: 522 GPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPA 581

Query: 760 PPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLL 819
           PP  P KP+        A           + L  +  +   Q +++  E R + ER+K +
Sbjct: 582 PPVTPSKPMAGTTDREEAT----------RLLAEKRRQAREQREREEQERRLQAERDKRM 631

Query: 820 CEGR--REKGSDPAMELRLKQPSEVELEE 846
            E +  RE  +    E   ++  E E  E
Sbjct: 632 REEQLAREAEARAEREAEARRREEQEARE 660


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 2   AHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPAT 61
           A  GGG GG G GG  G G+ G   G  G AG  + PV        LD        +P +
Sbjct: 59  AGGGGGGGGGGGGGGGGGGVGGG--GAGGGAGGGRSPVR------ELDMGAAERSREPGS 110

Query: 62  YNGFLEIMKEFKSQSIDTPGV 82
                E+  E K +  D  G+
Sbjct: 111 PR-LTEVSPELKDRKEDAKGM 130


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 16/33 (48%), Positives = 18/33 (54%)

Query: 5  GGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKL 37
          GGG GG G GG  GR  S +  G SG  G E +
Sbjct: 55 GGGGGGGGGGGGGGRSSSSSSSGSSGGGGSEAM 87


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 708 ASEESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHK 766
           A +E A+   ++P      P+ R +PA  P  +P P   G  GD PA      P P P  
Sbjct: 570 AGDEPAESPSETPGPSPAGPT-RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAG 628

Query: 767 PLDD 770
           P  D
Sbjct: 629 PAGD 632



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 708 ASEESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHK 766
           A +E A+   ++P  +   P+   +PA  P  +P P   G  GD PA      P P+P  
Sbjct: 530 AGDEPAESPSETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588

Query: 767 PLDD 770
           P  D
Sbjct: 589 PTRD 592



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 25/79 (31%), Positives = 29/79 (36%), Gaps = 15/79 (18%)

Query: 707 GASEESADEDRDS----PQGQTTDPSERKKPAPG------PHSSP-----PEEKGAFGDA 751
           G SE   +ED +      +G    PSE   P+P       P  SP     P   G  GD 
Sbjct: 494 GHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDE 553

Query: 752 PATEQPPLPPPAPHKPLDD 770
           PA      P P P  P  D
Sbjct: 554 PAESPSETPGPRPAGPAGD 572



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 710 EESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHKPL 768
           +E A+   ++P  +   P+   +PA  P  +P P   G  GD PA      P P+P  P 
Sbjct: 592 DEPAESPSETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650

Query: 769 DD 770
            D
Sbjct: 651 RD 652


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 3    HAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLP 38
            H+GGG GG G+GG  G G SG     SG +GH   P
Sbjct: 2290 HSGGGGGG-GSGGSGGGGGSGGGGAPSGGSGHSGGP 2324


>gi|239753043 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 451

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 17/83 (20%)

Query: 684 QGTIH---QLLHQFVPSL--FFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPH 738
           +GT H   +L  Q++  L  F SQ+L              SP G T  P    K APGPH
Sbjct: 353 EGTRHNDIELYSQYLEGLRRFISQELPAS-----------SPSGGTNRPDLSNKAAPGPH 401

Query: 739 SSPPEEKGAFGDAPATEQPPLPP 761
            +P  + G   D  A +  PL P
Sbjct: 402 PAPAPQ-GLHVDPRAAQGTPLQP 423


>gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
          Length = 442

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 28/81 (34%)

Query: 5  GGGSGGSGAGGPAGR------------GLSGARWGRS-----------GSAGHEKLPVHV 41
          GGG GG G GG  GR            GL G  WG S           GS+ H  +P+ +
Sbjct: 16 GGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAI 75

Query: 42 EDALTYLDQVKIRFGSDPATY 62
               Y     +R G    TY
Sbjct: 76 -----YRSPASLRGGHAGTTY 91


>gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]
          Length = 599

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 27/135 (20%)

Query: 571 LKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIES 630
           L++L+A +E+ R+ +    KI  E+YE+   +  + ++ NF+Q     L  K+ L  +E 
Sbjct: 347 LRKLQAADEKARKLK----KIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEE 402

Query: 631 VYD-----------EHQEQHSEGRSAPSSEPHL-----------IFVYEDRQILEDAAAL 668
             +           +  E+  +GR   S EP L           + ++E   I+EDA + 
Sbjct: 403 KEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSD 462

Query: 669 ISYY-VKRQPAIQKE 682
           + Y+ +   P + +E
Sbjct: 463 LGYHEIPEDPLVAEE 477


>gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]
          Length = 645

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 27/135 (20%)

Query: 571 LKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIES 630
           L++L+A +E+ R+ +    KI  E+YE+   +  + ++ NF+Q     L  K+ L  +E 
Sbjct: 347 LRKLQAADEKARKLK----KIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEE 402

Query: 631 VYD-----------EHQEQHSEGRSAPSSEPHL-----------IFVYEDRQILEDAAAL 668
             +           +  E+  +GR   S EP L           + ++E   I+EDA + 
Sbjct: 403 KEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSD 462

Query: 669 ISYY-VKRQPAIQKE 682
           + Y+ +   P + +E
Sbjct: 463 LGYHEIPEDPLVAEE 477


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 720  PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767
            P  Q   P  + +PAP P   PP+++      P  +QPP PPP   +P
Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 720  PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767
            P  Q   P  + +PAP P   PP+++      P  +QPP PPP   +P
Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 720  PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767
            P  Q   P  + +PAP P   PP+++      P  +QPP PPP   +P
Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,016,484
Number of Sequences: 37866
Number of extensions: 2411465
Number of successful extensions: 19458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 211
Number of HSP's that attempted gapping in prelim test: 17079
Number of HSP's gapped (non-prelim): 2128
length of query: 1162
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1049
effective length of database: 13,968,660
effective search space: 14653124340
effective search space used: 14653124340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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