BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens] (1162 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens] 2359 0.0 gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens] 1148 0.0 gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens] 1148 0.0 gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens] 1148 0.0 gi|18426913 drebrin 1 isoform b [Homo sapiens] 43 0.002 gi|18426915 drebrin 1 isoform a [Homo sapiens] 43 0.002 gi|18079216 CASK interacting protein 1 [Homo sapiens] 40 0.010 gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 39 0.029 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 39 0.038 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 39 0.038 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 38 0.064 gi|222537714 taxilin beta [Homo sapiens] 37 0.11 gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 37 0.11 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 37 0.11 gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 37 0.14 gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 37 0.14 gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 37 0.14 gi|62422577 neurobeachin [Homo sapiens] 37 0.14 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 37 0.14 gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 36 0.19 gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 36 0.19 gi|33286446 opioid growth factor receptor [Homo sapiens] 36 0.24 gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 36 0.24 gi|239753043 PREDICTED: hypothetical protein [Homo sapiens] 35 0.32 gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens] 35 0.32 gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] 35 0.32 gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] 35 0.32 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 35 0.32 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 35 0.32 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 35 0.32 >gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens] Length = 1162 Score = 2359 bits (6114), Expect = 0.0 Identities = 1162/1162 (100%), Positives = 1162/1162 (100%) Query: 1 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 60 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA Sbjct: 1 MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPA 60 Query: 61 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 120 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI Sbjct: 61 TYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNI 120 Query: 121 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 180 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP Sbjct: 121 QSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHP 180 Query: 181 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 240 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR Sbjct: 181 EIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKR 240 Query: 241 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 300 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG Sbjct: 241 SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG 300 Query: 301 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 360 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA Sbjct: 301 KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFA 360 Query: 361 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 420 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC Sbjct: 361 QFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAIC 420 Query: 421 KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY 480 KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY Sbjct: 421 KELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPY 480 Query: 481 EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ 540 EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ Sbjct: 481 EEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQ 540 Query: 541 RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY 600 RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY Sbjct: 541 RRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAY 600 Query: 601 LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ 660 LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ Sbjct: 601 LKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQ 660 Query: 661 ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP 720 ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP Sbjct: 661 ILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSP 720 Query: 721 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN 780 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN Sbjct: 721 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNN 780 Query: 781 WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS 840 WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS Sbjct: 781 WYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPS 840 Query: 841 EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL 900 EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL Sbjct: 841 EVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHL 900 Query: 901 VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR 960 VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR Sbjct: 901 VSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQR 960 Query: 961 KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK 1020 KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK Sbjct: 961 KGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLK 1020 Query: 1021 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT 1080 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT Sbjct: 1021 KFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGT 1080 Query: 1081 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET 1140 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET Sbjct: 1081 LCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCET 1140 Query: 1141 VHVHGLPVTRYRVQYSRRPASP 1162 VHVHGLPVTRYRVQYSRRPASP Sbjct: 1141 VHVHGLPVTRYRVQYSRRPASP 1162 >gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens] Length = 1273 Score = 1148 bits (2969), Expect = 0.0 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%) Query: 41 VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100 VEDAL+YLDQVK++FGS P YN FL+IMKEFKSQSIDTPGVI RVSQLF HPDLI+GF Sbjct: 123 VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182 Query: 101 NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140 N FLP GY+I++ N +N+ +P SQ ++ + A+ Sbjct: 183 NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242 Query: 141 KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160 Q P K KP Q P + V Sbjct: 243 PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302 Query: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217 EFN+AI+YVNKIK RF P+IY++FLEILHTYQKEQ N + G ++E+EV+ +V Sbjct: 303 EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362 Query: 218 ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274 A LF+ QEDLLSEFGQFLP+A S+ E +N+H K P+ + K RPS Sbjct: 363 ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422 Query: 275 L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326 + P KKK KL KD S+A K+G E FFDKVR+ L+S E YEN Sbjct: 423 NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482 Query: 327 FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385 FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF FK+FLG KE + +R+ +GI Sbjct: 483 FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542 Query: 386 SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445 + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE Sbjct: 543 AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579 Query: 446 CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505 VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI Sbjct: 580 ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630 Query: 506 RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565 RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP Sbjct: 631 RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690 Query: 566 AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625 AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL Sbjct: 691 AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750 Query: 626 NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685 NEIES+YDE QEQ +E + PHL YED+QILEDAAALI ++VKRQ IQKED+ Sbjct: 751 NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810 Query: 686 TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745 I Q++H F+P L F+Q+ DL EE +E+ D + + K G SPP+ K Sbjct: 811 KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865 Query: 746 GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805 F + A + + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I QA++Q Sbjct: 866 LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916 Query: 806 LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865 + E E+E E+ + +R+K PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID Sbjct: 917 IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976 Query: 866 TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925 +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E GA GG Sbjct: 977 SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036 Query: 926 LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985 L+++ R+ E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE ++DPVE + Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096 Query: 986 HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045 + YVE+Y+ ++ S E KPVFL RNL++ R+ + + + G+ +S K + Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156 Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105 V+S ++CRFKL+++KMV+++ SEDYMYRR L RA Q V R HQ F+ W + Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216 Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155 W +++V E A+ WLMGE E +VPC T C+T +H + + +YRV+Y Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%) Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176 + + +SH+H + QV P P+ + ++ +A+SY++++K +F Sbjct: 78 IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137 Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236 P++Y FL+I+ ++ + ++T G V + V+ LF+G DL+ F FLP Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187 Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282 + + P ++H + H P+ PS SAPA Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237 Score = 42.7 bits (99), Expect = 0.002 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%) Query: 38 PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84 PV A+ Y++++K RF P Y FLEI+ ++ + + TP V Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360 Query: 85 RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144 +V++LF DL+ F FLP N + + + +S + G K Q+ Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413 Query: 145 PYKEDKP 151 K +P Sbjct: 414 NNKPQRP 420 >gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens] Length = 1273 Score = 1148 bits (2969), Expect = 0.0 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%) Query: 41 VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100 VEDAL+YLDQVK++FGS P YN FL+IMKEFKSQSIDTPGVI RVSQLF HPDLI+GF Sbjct: 123 VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182 Query: 101 NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140 N FLP GY+I++ N +N+ +P SQ ++ + A+ Sbjct: 183 NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242 Query: 141 KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160 Q P K KP Q P + V Sbjct: 243 PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302 Query: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217 EFN+AI+YVNKIK RF P+IY++FLEILHTYQKEQ N + G ++E+EV+ +V Sbjct: 303 EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362 Query: 218 ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274 A LF+ QEDLLSEFGQFLP+A S+ E +N+H K P+ + K RPS Sbjct: 363 ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422 Query: 275 L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326 + P KKK KL KD S+A K+G E FFDKVR+ L+S E YEN Sbjct: 423 NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482 Query: 327 FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385 FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF FK+FLG KE + +R+ +GI Sbjct: 483 FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542 Query: 386 SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445 + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE Sbjct: 543 AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579 Query: 446 CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505 VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI Sbjct: 580 ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630 Query: 506 RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565 RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP Sbjct: 631 RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690 Query: 566 AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625 AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL Sbjct: 691 AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750 Query: 626 NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685 NEIES+YDE QEQ +E + PHL YED+QILEDAAALI ++VKRQ IQKED+ Sbjct: 751 NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810 Query: 686 TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745 I Q++H F+P L F+Q+ DL EE +E+ D + + K G SPP+ K Sbjct: 811 KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865 Query: 746 GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805 F + A + + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I QA++Q Sbjct: 866 LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916 Query: 806 LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865 + E E+E E+ + +R+K PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID Sbjct: 917 IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976 Query: 866 TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925 +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E GA GG Sbjct: 977 SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036 Query: 926 LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985 L+++ R+ E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE ++DPVE + Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096 Query: 986 HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045 + YVE+Y+ ++ S E KPVFL RNL++ R+ + + + G+ +S K + Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156 Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105 V+S ++CRFKL+++KMV+++ SEDYMYRR L RA Q V R HQ F+ W + Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216 Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155 W +++V E A+ WLMGE E +VPC T C+T +H + + +YRV+Y Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%) Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176 + + +SH+H + QV P P+ + ++ +A+SY++++K +F Sbjct: 78 IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137 Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236 P++Y FL+I+ ++ + ++T G V + V+ LF+G DL+ F FLP Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187 Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282 + + P ++H + H P+ PS SAPA Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237 Score = 42.7 bits (99), Expect = 0.002 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%) Query: 38 PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84 PV A+ Y++++K RF P Y FLEI+ ++ + + TP V Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360 Query: 85 RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144 +V++LF DL+ F FLP N + + + +S + G K Q+ Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413 Query: 145 PYKEDKP 151 K +P Sbjct: 414 NNKPQRP 420 >gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens] Length = 1273 Score = 1148 bits (2969), Expect = 0.0 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%) Query: 41 VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100 VEDAL+YLDQVK++FGS P YN FL+IMKEFKSQSIDTPGVI RVSQLF HPDLI+GF Sbjct: 123 VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182 Query: 101 NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140 N FLP GY+I++ N +N+ +P SQ ++ + A+ Sbjct: 183 NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242 Query: 141 KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160 Q P K KP Q P + V Sbjct: 243 PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302 Query: 161 EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217 EFN+AI+YVNKIK RF P+IY++FLEILHTYQKEQ N + G ++E+EV+ +V Sbjct: 303 EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362 Query: 218 ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274 A LF+ QEDLLSEFGQFLP+A S+ E +N+H K P+ + K RPS Sbjct: 363 ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422 Query: 275 L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326 + P KKK KL KD S+A K+G E FFDKVR+ L+S E YEN Sbjct: 423 NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482 Query: 327 FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385 FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF FK+FLG KE + +R+ +GI Sbjct: 483 FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542 Query: 386 SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445 + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE Sbjct: 543 AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579 Query: 446 CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505 VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI Sbjct: 580 ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630 Query: 506 RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565 RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP Sbjct: 631 RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690 Query: 566 AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625 AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL Sbjct: 691 AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750 Query: 626 NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685 NEIES+YDE QEQ +E + PHL YED+QILEDAAALI ++VKRQ IQKED+ Sbjct: 751 NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810 Query: 686 TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745 I Q++H F+P L F+Q+ DL EE +E+ D + + K G SPP+ K Sbjct: 811 KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865 Query: 746 GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805 F + A + + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I QA++Q Sbjct: 866 LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916 Query: 806 LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865 + E E+E E+ + +R+K PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID Sbjct: 917 IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976 Query: 866 TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925 +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E GA GG Sbjct: 977 SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036 Query: 926 LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985 L+++ R+ E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE ++DPVE + Sbjct: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096 Query: 986 HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045 + YVE+Y+ ++ S E KPVFL RNL++ R+ + + + G+ +S K + Sbjct: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156 Query: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105 V+S ++CRFKL+++KMV+++ SEDYMYRR L RA Q V R HQ F+ W + Sbjct: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216 Query: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155 W +++V E A+ WLMGE E +VPC T C+T +H + + +YRV+Y Sbjct: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%) Query: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176 + + +SH+H + QV P P+ + ++ +A+SY++++K +F Sbjct: 78 IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137 Query: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236 P++Y FL+I+ ++ + ++T G V + V+ LF+G DL+ F FLP Sbjct: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187 Query: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282 + + P ++H + H P+ PS SAPA Sbjct: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237 Score = 42.7 bits (99), Expect = 0.002 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%) Query: 38 PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84 PV A+ Y++++K RF P Y FLEI+ ++ + + TP V Sbjct: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360 Query: 85 RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144 +V++LF DL+ F FLP N + + + +S + G K Q+ Sbjct: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413 Query: 145 PYKEDKP 151 K +P Sbjct: 414 NNKPQRP 420 >gi|18426913 drebrin 1 isoform b [Homo sapiens] Length = 651 Score = 43.1 bits (100), Expect = 0.002 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 51/211 (24%) Query: 572 KRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNF---KQNDTKALRSKSLLNEI 628 +R KA +E R Q+ + +EQ E+ Q + KQ +A +K L E Sbjct: 197 ERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE- 255 Query: 629 ESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIH 688 +S++ +H+++ E S +E+AAA+I+ Q+ D Sbjct: 256 QSIFGDHRDEEEETHMKKSESE-----------VEEAAAIIA---------QRPDN---- 291 Query: 689 QLLHQFVPSLFFSQQLDLGASEESADEDRDSP----QGQTTDPSERKKPAPGPHSSPPEE 744 P FF QQ + AS + D SP G D R P P P SP + Sbjct: 292 -------PREFFKQQ-ERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDS 343 Query: 745 -----------KGAFGDAPATEQPPLPPPAP 764 + A + +++ PPLPPP P Sbjct: 344 STASTPVAEQIERALDEVTSSQPPPLPPPPP 374 >gi|18426915 drebrin 1 isoform a [Homo sapiens] Length = 649 Score = 43.1 bits (100), Expect = 0.002 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 51/211 (24%) Query: 572 KRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNF---KQNDTKALRSKSLLNEI 628 +R KA +E R Q+ + +EQ E+ Q + KQ +A +K L E Sbjct: 195 ERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKE- 253 Query: 629 ESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIH 688 +S++ +H+++ E S +E+AAA+I+ Q+ D Sbjct: 254 QSIFGDHRDEEEETHMKKSESE-----------VEEAAAIIA---------QRPDN---- 289 Query: 689 QLLHQFVPSLFFSQQLDLGASEESADEDRDSP----QGQTTDPSERKKPAPGPHSSPPEE 744 P FF QQ + AS + D SP G D R P P P SP + Sbjct: 290 -------PREFFKQQ-ERVASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDS 341 Query: 745 -----------KGAFGDAPATEQPPLPPPAP 764 + A + +++ PPLPPP P Sbjct: 342 STASTPVAEQIERALDEVTSSQPPPLPPPPP 372 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 40.4 bits (93), Expect = 0.010 Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 721 QGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSL 774 QG T P+ +K P PGP S PE K A G P P PPP KP+ V L Sbjct: 1240 QGSPT-PTSKKVPLPGPGS--PEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGL 1290 >gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] Length = 1312 Score = 38.9 bits (89), Expect = 0.029 Identities = 52/232 (22%), Positives = 93/232 (40%), Gaps = 36/232 (15%) Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613 ++ + +++P + +L + + + EE +E ++ + R + E+ L+ + Q + Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430 Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673 D +ALR + + E + ++Q E R + + RQ+ ++ A L S Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481 Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724 ++Q +QK+ Q QLL L+ G AD E+R Q Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533 Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDD 770 P + KP P P +SP G P ++P P PHK L D Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSLQD 584 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 38.5 bits (88), Expect = 0.038 Identities = 34/178 (19%), Positives = 72/178 (40%), Gaps = 8/178 (4%) Query: 466 WSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEK 525 W+ + K EE++ E++ E + + IR E ++ M E +EK Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350 Query: 526 FRLDDSLGGTSEVIQRRAIYRIY--GDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWRE 583 R + + E RR ++ +K E+ E + + ++ + K E + Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410 Query: 584 AQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSE 641 Q+ K+WR++ + + Q ++ + K R + ++E E + +E + Q E Sbjct: 411 RQEQEAKMWRQE------EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 38.5 bits (88), Expect = 0.038 Identities = 34/178 (19%), Positives = 72/178 (40%), Gaps = 8/178 (4%) Query: 466 WSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEK 525 W+ + K EE++ E++ E + + IR E ++ M E +EK Sbjct: 352 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411 Query: 526 FRLDDSLGGTSEVIQRRAIYRIY--GDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWRE 583 R + + E RR ++ +K E+ E + + ++ + K E + Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471 Query: 584 AQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSE 641 Q+ K+WR++ + + Q ++ + K R + ++E E + +E + Q E Sbjct: 472 RQEQEAKMWRQE------EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 37.7 bits (86), Expect = 0.064 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 12/81 (14%) Query: 694 FVPSLFFSQQLDLGASEESADE---DRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGD 750 + L FS + D S+E E D S G+ P K P+S PP K A+ + Sbjct: 335 YTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAE 394 Query: 751 ---------APATEQPPLPPP 762 P +PPLPPP Sbjct: 395 TSRPPETEPGPPAPKPPLPPP 415 Score = 36.2 bits (82), Expect = 0.19 Identities = 19/54 (35%), Positives = 22/54 (40%) Query: 711 ESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAP 764 ++A + P P K P P PH P G GD P PP PPAP Sbjct: 389 KTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP 442 Score = 32.0 bits (71), Expect = 3.5 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 23/85 (27%) Query: 700 FSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPL 759 ++++L E+ D D + +G R + PPE G G++P +E PP Sbjct: 335 YTEKLKFSDEEDGRDSDEEGAEGH------RDSQSASGEERPPEADGKKGNSPNSE-PPT 387 Query: 760 P----------------PPAPHKPL 768 P PPAP PL Sbjct: 388 PKTAWAETSRPPETEPGPPAPKPPL 412 >gi|222537714 taxilin beta [Homo sapiens] Length = 684 Score = 37.0 bits (84), Expect = 0.11 Identities = 42/177 (23%), Positives = 73/177 (41%), Gaps = 17/177 (9%) Query: 592 WREQYE---KAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSS 648 W+ ++E KA L ++ +A+ K+ + ++ L N ++ +E E H + R A S Sbjct: 405 WKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEIS 464 Query: 649 EP-----HLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLH--QFVPSLFFS 701 E H + + D Q A++ + T ++H + P Sbjct: 465 EKDDQSQHNSDEEPESNVSVDQEIDAEEVNSVQTAVK--NLATAFMIIHHPESTPHQSKE 522 Query: 702 QQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPP 758 Q ++G+S+ESAD P+ PS R +P P +P E DA +PP Sbjct: 523 TQPEIGSSQESADAALKEPEQPPLIPS-RDSESPLPPLTPQAEAEGGSDA----EPP 574 >gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] Length = 532 Score = 37.0 bits (84), Expect = 0.11 Identities = 17/30 (56%), Positives = 20/30 (66%) Query: 4 AGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33 +GGGSG G GG AG G G+ G SG+AG Sbjct: 489 SGGGSGSGGGGGGAGGGGGGSSGGGSGTAG 518 Score = 34.7 bits (78), Expect = 0.54 Identities = 17/31 (54%), Positives = 20/31 (64%), Gaps = 1/31 (3%) Query: 3 HAGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33 H GGGSG GAGG +G G SG+ G G+ G Sbjct: 475 HRGGGSGSGGAGGGSGGG-SGSGGGGGGAGG 504 Score = 32.7 bits (73), Expect = 2.1 Identities = 15/30 (50%), Positives = 18/30 (60%) Query: 4 AGGGSGGSGAGGPAGRGLSGARWGRSGSAG 33 +GG GGSG G +G G GA G GS+G Sbjct: 482 SGGAGGGSGGGSGSGGGGGGAGGGGGGSSG 511 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 37.0 bits (84), Expect = 0.11 Identities = 34/160 (21%), Positives = 58/160 (36%), Gaps = 18/160 (11%) Query: 607 QAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAA 666 Q +N N + ++L I ++ + +Q AP + + E + Sbjct: 1136 QLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAP-----------EESLKEAPS 1184 Query: 667 ALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTD 726 A + Q ++ Q + + S Q G+ EE+ + PQG Sbjct: 1185 APVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRT 1244 Query: 727 PSERKKPAPG--PHSSPPEEKGAFGDAPATEQPPLPPPAP 764 P+ ++ A PH PPE++ P PP PPP P Sbjct: 1245 PTMPQEEAAACPPHILPPEKR-----PPEPPGPPPPPPPP 1279 >gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] Length = 1303 Score = 36.6 bits (83), Expect = 0.14 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%) Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613 ++ + +++P + +L + + + EE +E ++ + R + E+ L+ + Q + Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430 Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673 D +ALR + + E + ++Q E R + + RQ+ ++ A L S Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481 Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724 ++Q +QK+ Q QLL L+ G AD E+R Q Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533 Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768 P + KP P P +SP G P ++P P PHK L Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582 >gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] Length = 1332 Score = 36.6 bits (83), Expect = 0.14 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%) Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613 ++ + +++P + +L + + + EE +E ++ + R + E+ L+ + Q + Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430 Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673 D +ALR + + E + ++Q E R + + RQ+ ++ A L S Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481 Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724 ++Q +QK+ Q QLL L+ G AD E+R Q Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533 Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768 P + KP P P +SP G P ++P P PHK L Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582 >gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] Length = 1295 Score = 36.6 bits (83), Expect = 0.14 Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 36/230 (15%) Query: 554 EIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQ 613 ++ + +++P + +L + + + EE +E ++ + R + E+ L+ + Q + Sbjct: 374 QLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR---RL 430 Query: 614 NDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYV 673 D +ALR + + E + ++Q E R + + RQ+ ++ A L S Sbjct: 431 EDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQ---------RQLQQEHAYLKSLQQ 481 Query: 674 KRQPA-IQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESAD--------EDRDSPQGQT 724 ++Q +QK+ Q QLL L+ G AD E+R Q Sbjct: 482 QQQQQQLQKQQQ---QQLLPGDRKPLYH-----YGRGMNPADKPAWAREVEERTRMNKQQ 533 Query: 725 TDPSERKKPA------PGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPL 768 P + KP P P +SP G P ++P P PHK L Sbjct: 534 NSPLAKSKPGSTGPEPPIPQASPGPP-GPLSQTPPMQRPVEPQEGPHKSL 582 >gi|62422577 neurobeachin [Homo sapiens] Length = 2946 Score = 36.6 bits (83), Expect = 0.14 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 4 AGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRF 55 AGGG GGSG GG G G+ R G SGS G LP + + + ++++F Sbjct: 25 AGGGGGGSGGGGTGGSGMGELR-GASGS-GSVMLPAGMINPSVPIRNIRMKF 74 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 36.6 bits (83), Expect = 0.14 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 19/149 (12%) Query: 707 GASEESADEDRDSPQGQTTDP-SERKKPAPGPHSSPPEEKGAFGDAPA-----TEQP-PL 759 G ++S + R S + ++ P S PAP P +PP+++ + P T P P Sbjct: 522 GPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPA 581 Query: 760 PPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLL 819 PP P KP+ A + L + + Q +++ E R + ER+K + Sbjct: 582 PPVTPSKPMAGTTDREEAT----------RLLAEKRRQAREQREREEQERRLQAERDKRM 631 Query: 820 CEGR--REKGSDPAMELRLKQPSEVELEE 846 E + RE + E ++ E E E Sbjct: 632 REEQLAREAEARAEREAEARRREEQEARE 660 >gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] Length = 331 Score = 36.2 bits (82), Expect = 0.19 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 2 AHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPAT 61 A GGG GG G GG G G+ G G G AG + PV LD +P + Sbjct: 59 AGGGGGGGGGGGGGGGGGGVGGG--GAGGGAGGGRSPVR------ELDMGAAERSREPGS 110 Query: 62 YNGFLEIMKEFKSQSIDTPGV 82 E+ E K + D G+ Sbjct: 111 PR-LTEVSPELKDRKEDAKGM 130 >gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] Length = 409 Score = 36.2 bits (82), Expect = 0.19 Identities = 16/33 (48%), Positives = 18/33 (54%) Query: 5 GGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKL 37 GGG GG G GG GR S + G SG G E + Sbjct: 55 GGGGGGGGGGGGGGRSSSSSSSGSSGGGGSEAM 87 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 35.8 bits (81), Expect = 0.24 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 708 ASEESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHK 766 A +E A+ ++P P+ R +PA P +P P G GD PA P P P Sbjct: 570 AGDEPAESPSETPGPSPAGPT-RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAG 628 Query: 767 PLDD 770 P D Sbjct: 629 PAGD 632 Score = 33.9 bits (76), Expect = 0.92 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 2/64 (3%) Query: 708 ASEESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHK 766 A +E A+ ++P + P+ +PA P +P P G GD PA P P+P Sbjct: 530 AGDEPAESPSETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588 Query: 767 PLDD 770 P D Sbjct: 589 PTRD 592 Score = 33.5 bits (75), Expect = 1.2 Identities = 25/79 (31%), Positives = 29/79 (36%), Gaps = 15/79 (18%) Query: 707 GASEESADEDRDS----PQGQTTDPSERKKPAPG------PHSSP-----PEEKGAFGDA 751 G SE +ED + +G PSE P+P P SP P G GD Sbjct: 494 GHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDE 553 Query: 752 PATEQPPLPPPAPHKPLDD 770 PA P P P P D Sbjct: 554 PAESPSETPGPRPAGPAGD 572 Score = 32.3 bits (72), Expect = 2.7 Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 2/62 (3%) Query: 710 EESADEDRDSPQGQTTDPSERKKPAPGPHSSP-PEEKGAFGDAPATEQPPLPPPAPHKPL 768 +E A+ ++P + P+ +PA P +P P G GD PA P P+P P Sbjct: 592 DEPAESPSETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650 Query: 769 DD 770 D Sbjct: 651 RD 652 >gi|45439359 triple functional domain (PTPRF interacting) [Homo sapiens] Length = 3097 Score = 35.8 bits (81), Expect = 0.24 Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 3 HAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLP 38 H+GGG GG G+GG G G SG SG +GH P Sbjct: 2290 HSGGGGGG-GSGGSGGGGGSGGGGAPSGGSGHSGGP 2324 >gi|239753043 PREDICTED: hypothetical protein [Homo sapiens] Length = 451 Score = 35.4 bits (80), Expect = 0.32 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 17/83 (20%) Query: 684 QGTIH---QLLHQFVPSL--FFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPH 738 +GT H +L Q++ L F SQ+L SP G T P K APGPH Sbjct: 353 EGTRHNDIELYSQYLEGLRRFISQELPAS-----------SPSGGTNRPDLSNKAAPGPH 401 Query: 739 SSPPEEKGAFGDAPATEQPPLPP 761 +P + G D A + PL P Sbjct: 402 PAPAPQ-GLHVDPRAAQGTPLQP 423 >gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens] Length = 442 Score = 35.4 bits (80), Expect = 0.32 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 28/81 (34%) Query: 5 GGGSGGSGAGGPAGR------------GLSGARWGRS-----------GSAGHEKLPVHV 41 GGG GG G GG GR GL G WG S GS+ H +P+ + Sbjct: 16 GGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHSVPIAI 75 Query: 42 EDALTYLDQVKIRFGSDPATY 62 Y +R G TY Sbjct: 76 -----YRSPASLRGGHAGTTY 91 >gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] Length = 599 Score = 35.4 bits (80), Expect = 0.32 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 27/135 (20%) Query: 571 LKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIES 630 L++L+A +E+ R+ + KI E+YE+ + + ++ NF+Q L K+ L +E Sbjct: 347 LRKLQAADEKARKLK----KIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEE 402 Query: 631 VYD-----------EHQEQHSEGRSAPSSEPHL-----------IFVYEDRQILEDAAAL 668 + + E+ +GR S EP L + ++E I+EDA + Sbjct: 403 KEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSD 462 Query: 669 ISYY-VKRQPAIQKE 682 + Y+ + P + +E Sbjct: 463 LGYHEIPEDPLVAEE 477 >gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] Length = 645 Score = 35.4 bits (80), Expect = 0.32 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 27/135 (20%) Query: 571 LKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIES 630 L++L+A +E+ R+ + KI E+YE+ + + ++ NF+Q L K+ L +E Sbjct: 347 LRKLQAADEKARKLK----KIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEE 402 Query: 631 VYD-----------EHQEQHSEGRSAPSSEPHL-----------IFVYEDRQILEDAAAL 668 + + E+ +GR S EP L + ++E I+EDA + Sbjct: 403 KEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSD 462 Query: 669 ISYY-VKRQPAIQKE 682 + Y+ + P + +E Sbjct: 463 LGYHEIPEDPLVAEE 477 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 35.4 bits (80), Expect = 0.32 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 720 PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767 P Q P + +PAP P PP+++ P +QPP PPP +P Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 35.4 bits (80), Expect = 0.32 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 720 PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767 P Q P + +PAP P PP+++ P +QPP PPP +P Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 35.4 bits (80), Expect = 0.32 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 720 PQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKP 767 P Q P + +PAP P PP+++ P +QPP PPP +P Sbjct: 1655 PPQQPQPPPPQPQPAPQP--PPPQQQPQQQPQPQPQQPPPPPPPQQQP 1700 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,016,484 Number of Sequences: 37866 Number of extensions: 2411465 Number of successful extensions: 19458 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 73 Number of HSP's successfully gapped in prelim test: 211 Number of HSP's that attempted gapping in prelim test: 17079 Number of HSP's gapped (non-prelim): 2128 length of query: 1162 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1049 effective length of database: 13,968,660 effective search space: 14653124340 effective search space used: 14653124340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.