Guide to the Human Genome
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Name: TRIO Sequence: fasta or formatted (3097aa) NCBI GI: 45439359
Description:

triple functional domain (PTPRF interacting)

Referenced in:

Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6        203           4
 C cysteine            1.7         54           2
 D aspartate           5.9        182           2
 E glutamate           8.1        251           3
 F phenylalanine       3.2        100           2
 G glycine             6.2        191           7
 H histidine           3.4        105           3
 I isoleucine          4.8        148           2
 K lysine              6.5        200           3
 L leucine            10.2        315           3
 M methionine          2.2         67           2
 N asparagine          3.4        106           2
 P proline             4.4        135           3
 Q glutamine           5.7        177           4
 R arginine            5.4        168           2
 S serine              9.3        287           5
 T threonine           4.4        136           2
 V valine              5.7        177           2
 W tryptophan          1.1         34           1
 Y tyrosine            2.0         61           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   triple functional domain (PTPRF interacting) 
KALRN                 0.527   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.419   kalirin, RhoGEF kinase isoform 2 
KALRN                 0.087   kalirin, RhoGEF kinase isoform 3 
GEFT                  0.071   RhoA/RAC/CDC42 exchange factor isoform 3 
GEFT                  0.071   RhoA/RAC/CDC42 exchange factor isoform 1 
MCF2L                 0.035   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.035   MCF.2 cell line derived transforming sequence-like ...
OBSCN                 0.033   obscurin, cytoskeletal calmodulin and titin-interac...
DAPK1                 0.033   death-associated protein kinase 1 
DAPK3                 0.032   death-associated protein kinase 3 
SESTD1                0.032   SEC14 and spectrin domains 1 
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
PLEKHG4B              0.029   pleckstrin homology domain containing, family G (wi...
DAPK2                 0.028   death-associated kinase 2 
PLEKHG4               0.027   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.027   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.027   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.027   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.027   pleckstrin homology domain containing, family G (wit...
SPEG                  0.026   SPEG complex locus 
STK17A                0.026   serine/threonine kinase 17a 
STK17B                0.025   serine/threonine kinase 17B 
MCF2L2                0.025   Rho family guanine-nucleotide exchange factor 
MYLK                  0.025   myosin light chain kinase isoform 1 
MYLK                  0.025   myosin light chain kinase isoform 2 
CAMK4                 0.024   calcium/calmodulin-dependent protein kinase IV 
MYLK4                 0.024   myosin light chain kinase family, member 4 
MYLK3                 0.023   myosin light chain kinase 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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