BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13376429 hypothetical protein LOC80011 [Homo sapiens] (254 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13376429 hypothetical protein LOC80011 [Homo sapiens] 507 e-144 gi|18426913 drebrin 1 isoform b [Homo sapiens] 53 2e-07 gi|18426915 drebrin 1 isoform a [Homo sapiens] 53 2e-07 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 4e-07 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 51 9e-07 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 50 1e-06 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 1e-06 gi|148746195 trichohyalin [Homo sapiens] 50 2e-06 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 2e-06 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 2e-06 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 50 2e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 49 4e-06 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 6e-06 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 9e-06 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 9e-06 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 47 2e-05 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 47 2e-05 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 47 2e-05 gi|221219020 NYD-SP11 protein [Homo sapiens] 46 3e-05 gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 46 3e-05 gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 46 3e-05 gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 46 3e-05 gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 46 3e-05 gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 46 4e-05 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 4e-05 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 8e-05 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 8e-05 gi|92859701 myosin VI [Homo sapiens] 45 8e-05 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 1e-04 gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 44 1e-04 >gi|13376429 hypothetical protein LOC80011 [Homo sapiens] Length = 254 Score = 507 bits (1306), Expect = e-144 Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQE 60 MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQE Sbjct: 1 MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQE 60 Query: 61 QKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLK 120 QKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLK Sbjct: 61 QKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLK 120 Query: 121 KVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDK 180 KVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDK Sbjct: 121 KVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDK 180 Query: 181 NQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKI 240 NQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKI Sbjct: 181 NQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKI 240 Query: 241 VSSIFRTNTFLEAP 254 VSSIFRTNTFLEAP Sbjct: 241 VSSIFRTNTFLEAP 254 >gi|18426913 drebrin 1 isoform b [Homo sapiens] Length = 651 Score = 53.1 bits (126), Expect = 2e-07 Identities = 47/190 (24%), Positives = 92/190 (48%), Gaps = 36/190 (18%) Query: 17 SEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFK 76 ++A ++ +R R++ WE+ +K E E +E ++L ERL+ +++R +QE +EQ Sbjct: 168 TDAAVEMKRINREQFWEQAKKEE---ELRKEEERKKALDERLRFEQERMEQERQEQ---- 220 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 +E E + + +++ IE+ RR+++ E +E + LK+ I +++ E E Sbjct: 221 ------EERERRYRE----REQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE--- 267 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPD-PEPDDKNQEPSSCKSLGNTSL 195 ET K S++++ E ++ +PD P K QE + S G+ + Sbjct: 268 -----ETHMKKSESEV----------EEAAAIIAQRPDNPREFFKQQERVASASAGSCDV 312 Query: 196 SGPSIHCPSA 205 P H P + Sbjct: 313 PSPFNHRPGS 322 >gi|18426915 drebrin 1 isoform a [Homo sapiens] Length = 649 Score = 53.1 bits (126), Expect = 2e-07 Identities = 47/190 (24%), Positives = 92/190 (48%), Gaps = 36/190 (18%) Query: 17 SEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFK 76 ++A ++ +R R++ WE+ +K E E +E ++L ERL+ +++R +QE +EQ Sbjct: 166 TDAAVEMKRINREQFWEQAKKEE---ELRKEEERKKALDERLRFEQERMEQERQEQ---- 218 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 +E E + + +++ IE+ RR+++ E +E + LK+ I +++ E E Sbjct: 219 ------EERERRYRE----REQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEE--- 265 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPD-PEPDDKNQEPSSCKSLGNTSL 195 ET K S++++ E ++ +PD P K QE + S G+ + Sbjct: 266 -----ETHMKKSESEV----------EEAAAIIAQRPDNPREFFKQQERVASASAGSCDV 310 Query: 196 SGPSIHCPSA 205 P H P + Sbjct: 311 PSPFNHRPGS 320 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 52.4 bits (124), Expect = 4e-07 Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 9/161 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDP------EECPEEVYDPRSLYERLQEQKDRK 65 K+R E ++E+RK E K+++ ++ + PEE+ + ER +E++ K Sbjct: 464 KRREEEERRMEEQRKAACAE--KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEK 521 Query: 66 QQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGIS 125 +QE E + K + R +++ L++ +Q +EK+R++E+ KEL+ + K++ Sbjct: 522 EQEQERE-KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKM 580 Query: 126 QENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGN 166 +E +KE E + + +E K + + L K +S S N Sbjct: 581 KEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCN 621 Score = 43.1 bits (100), Expect = 2e-04 Identities = 36/157 (22%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Query: 16 VSEAELDERRKRRQE-EWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFK 74 + E E ++ R+R +E E E+ ++ E E E + +++K R+ ++ +Q K Sbjct: 504 IREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563 Query: 75 FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRN-NLKKVGISQENKKEVE 133 K + R ++++ L ++ Q++ E ++ E+L+E E R NL+ + QE++ Sbjct: 564 EKELERQKEKEKE--LQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCN 621 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 K+ +P+ T+ ++++ A V H++ S R Sbjct: 622 KE--EEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656 Score = 34.3 bits (77), Expect = 0.11 Identities = 40/184 (21%), Positives = 79/184 (42%), Gaps = 22/184 (11%) Query: 4 GDDGNLIIKKRFVSEAELDERRKRRQEEW----EKVRKPEDPEECPEEVYDPRSLYERLQ 59 G G K++ E E+ ++R+R+Q E E+ RK + EE R++ Sbjct: 427 GRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEE------------RRME 474 Query: 60 EQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNL 119 EQ+ E K K + L E E R++E +++ RE+EL++ +E Sbjct: 475 EQRKAACAE-----KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE- 528 Query: 120 KKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDD 179 K+ +E ++E EK+L + + + + K + E ++++K + + Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588 Query: 180 KNQE 183 +E Sbjct: 589 LEKE 592 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 51.2 bits (121), Expect = 9e-07 Identities = 39/180 (21%), Positives = 89/180 (49%), Gaps = 8/180 (4%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQE----QKDRKQQ 67 +K + E ++ ER ++ QE+ EK+R+ E+ EE+ + R QE +K+ K + Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347 Query: 68 EYEEQFKFKNMVRGLDE---DETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGI 124 E EE+ + +R +E +E ++ RQ++ + R+EE+++E +E +++ Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407 Query: 125 SQENKK-EVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 QE K E E+K+ + E + + + + ++ + + ++++ E + +E Sbjct: 408 EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467 Score = 46.6 bits (109), Expect = 2e-05 Identities = 35/128 (27%), Positives = 71/128 (55%), Gaps = 9/128 (7%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 ++++ + ++ E+ ++RQEE EK+R+ E +E +++ E+++EQ++ K +E E Sbjct: 349 LEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQE---EKIREQEE-KIREQE 403 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEE--LKELKEYRNNLKKVGISQEN 128 E + + G E E ++ QE EK RR+EE ++ K+ R +K+ +E Sbjct: 404 EMMQEQEEKMG--EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461 Query: 129 KKEVEKKL 136 +E E+K+ Sbjct: 462 MQEQEEKM 469 Score = 45.4 bits (106), Expect = 5e-05 Identities = 38/131 (29%), Positives = 69/131 (52%), Gaps = 14/131 (10%) Query: 16 VSEAELDERRKRRQEE--WEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEY---- 69 V E EL R ++QEE W + K ++ EE +E + R QE+K R+Q+E Sbjct: 273 VEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI----REQEEKMRRQEEMMWEK 328 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELI----EKQRREEELKELKEYRNNLKKVGIS 125 EE+ + + + E++ L+E +QE I EK++ EE+++E ++ + K+ Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388 Query: 126 QENKKEVEKKL 136 +E +E E+K+ Sbjct: 389 EEKIREQEEKI 399 Score = 45.4 bits (106), Expect = 5e-05 Identities = 35/131 (26%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 18 EAELDERRKRRQEEWEKVRKPEDP-----EECPEEVYDPRSLYERLQEQKDRKQQEYEEQ 72 E ++ E+ + QE+ EK+ + E+ EE E+ R E+++EQ ++K +E EE+ Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIREQEEK 454 Query: 73 FK-----FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEE--LKELKEYRNNLKKVGIS 125 + + + E E ++ ++ QE EK RR+EE ++ K+ R +K+ Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514 Query: 126 QENKKEVEKKL 136 +E +E E+K+ Sbjct: 515 EEMMQEQEEKM 525 Score = 40.8 bits (94), Expect = 0.001 Identities = 31/149 (20%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQE---QKDRKQQEYEEQFK 74 E ++ E+ KR+++E + R+ E E E++ + + + +E +++ K E EE+ + Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428 Query: 75 FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK 134 + E++ ++ R+QE EK R +EE+ + +E + ++ + ++ K E+ Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQE--EKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486 Query: 135 KLTVKPIETKNKFSQAKLLAGAVKHKSSE 163 + ++ E K + + K+ K + E Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQE 515 Score = 38.5 bits (88), Expect = 0.006 Identities = 33/151 (21%), Positives = 70/151 (46%), Gaps = 20/151 (13%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDR------- 64 +K + E E+ E+ ++ + + EK+R+ E ++ E+ R E +QEQ+++ Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQE--KKIREQEEKIREQEEMMQEQEEKMGEQEGK 475 Query: 65 ------KQQEYEEQF-----KFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELK 113 K QE EE+ K + + + E E ++ QE EK +EE + Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535 Query: 114 EYRNNLKKVGISQENKKEVEKKLTVKPIETK 144 E + ++ + ++ +K E+++ ++ E K Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566 Score = 34.3 bits (77), Expect = 0.11 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 21/121 (17%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 +AE D K Q K++ + E L+ RL +Q++ K EE+ + + Sbjct: 252 QAEADHLGKELQSVSAKLQAQVEENE----------LWNRLNQQQEEKMWRQEEKIQER- 300 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE--YRNNLKKVGISQENKKEVEKK 135 E++ +E R+QE EK RR+EE+ KE R + + +E +E+E+K Sbjct: 301 ------EEKIQEQEEKIREQE--EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352 Query: 136 L 136 + Sbjct: 353 M 353 Score = 31.6 bits (70), Expect = 0.70 Identities = 25/100 (25%), Positives = 55/100 (55%), Gaps = 16/100 (16%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDR------KQQEYEE 71 EA++ E+ ++ + + EK+R+ E ++ E+ R E +QEQ+++ K E EE Sbjct: 480 EAKMQEQEEKMRRQEEKIREQE--KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE 111 + + + E++ +E R+QE + +++EE+++E Sbjct: 538 KMQEQ-------EEKMRRQEEKMREQE-VRLRQQEEKMQE 569 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 50.4 bits (119), Expect = 1e-06 Identities = 42/174 (24%), Positives = 92/174 (52%), Gaps = 10/174 (5%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E ++ E + Q++ EK+R+ E E+ EE + E++Q Q+++ Q++ E+ ++ + Sbjct: 433 EEKIRELEEMMQDQEEKLREVE--EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490 Query: 78 MVRGLD---EDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK 134 +++ + E E + + E EK + +EE + +E + ++V + Q+ +K E+ Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550 Query: 135 KLTVKPIETK-NKFSQ-AKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSS 186 ++ ++ +E + K Q A+LL GA + S+ + L P + + K+QE S Sbjct: 551 EVRLQELEERLGKLGQKAELLGGAGRESGSQ---RLPTLTPILQVELKSQEAQS 601 Score = 43.1 bits (100), Expect = 2e-04 Identities = 32/120 (26%), Positives = 64/120 (53%), Gaps = 6/120 (5%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPR-SLYERLQEQKDRKQQEYEEQFKFKNMV 79 E + R QEE W + K + EE E D E+++EQ+++ +++ E+ ++ + + Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376 Query: 80 RGLDEDETNFLDEVSRQQELI---EKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 R DE +E+ RQ+E I E++R+E+ ++ K+ R +K+ +E E+K+ Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436 Score = 42.7 bits (99), Expect = 3e-04 Identities = 37/173 (21%), Positives = 83/173 (47%), Gaps = 19/173 (10%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K E ++ E+ + + EK+R+ E+ EE + E+++EQ ++ Q++ EE Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE--EKIREQDEKIQEQEEE 389 Query: 72 QFKFKNMVRGLDEDETNFL----------DEVSRQQELIEKQRREEELKELKEYRNNLKK 121 ++ + +R +E + DE R+QE E R+EE+++EL+E + Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEEKIRELEEMMQD--- 445 Query: 122 VGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPD 174 +E +EVE+K+ + + + + + + ++ + ++ K LK + Sbjct: 446 ---QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495 Score = 40.8 bits (94), Expect = 0.001 Identities = 33/177 (18%), Positives = 90/177 (50%), Gaps = 9/177 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E+ ++ E+ K+R+ E+ EE + E+++EQ+D+ ++ E+ Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE--EKIREQEDKMWRQEEK 354 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ-----RREEELKELKEYRNNLKKVGISQ 126 + + +R +E +++ Q E I++Q R+EE+++E +E R +K+ + Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ--EKMWRQE 412 Query: 127 ENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + +E ++K+ + E + + + L ++ + + ++++ + E + +E Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469 Score = 39.7 bits (91), Expect = 0.003 Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 11/128 (8%) Query: 20 ELDERRKRRQEE-W---EKVRKPEDP--EECPEEVYDPRSLYERLQEQKDRKQQEYEEQF 73 E DE+ + ++EE W EK+R+ E+ E+ + R E+++EQ++ ++ E+ Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 Query: 74 KFKNMVRG----LDEDETNFLDEVSRQQELIEK-QRREEELKELKEYRNNLKKVGISQEN 128 + + M++ L E E +E + QE EK QR+EE+++E +E +K+ +E Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497 Query: 129 KKEVEKKL 136 E E+K+ Sbjct: 498 IWEQEEKM 505 Score = 38.1 bits (87), Expect = 0.007 Identities = 40/187 (21%), Positives = 74/187 (39%), Gaps = 53/187 (28%) Query: 18 EAELDERRKRRQEEWEK---VRKPEDPEECPEEVY------------------------- 49 EA L+ R++R + W++ + + ED ++C E + Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129 Query: 50 DPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDE------------DETNFLDEVSRQQ 97 + +S +++ QE+ + K + ++ K L E +ET D R Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189 Query: 98 ELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK-----------KLTVKPIETKNK 146 IEK +E + L+ YRN + + ++N + EK +L VK + K K Sbjct: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK--DLKRK 247 Query: 147 FSQAKLL 153 +A+LL Sbjct: 248 LERAQLL 254 Score = 33.9 bits (76), Expect = 0.14 Identities = 32/125 (25%), Positives = 64/125 (51%), Gaps = 20/125 (16%) Query: 16 VSEAELDERRKRRQEE--WEKVRKPEDPEE--CPEEVYDPRSLYERLQEQKDRKQQEYEE 71 V E EL ++QEE W + K ++ EE C +E+ +++EQ+++ ++ E+ Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL--------KIREQEEKMWRQEEK 333 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + + +R E E D++ RQ+E I +Q + +E K +R +K+ E +E Sbjct: 334 MHEQEEKIR---EQE----DKMWRQEEKIREQEEKIREQEEKMWRQE-EKIREQDEKIQE 385 Query: 132 VEKKL 136 E+++ Sbjct: 386 QEEEM 390 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 50.4 bits (119), Expect = 1e-06 Identities = 42/174 (24%), Positives = 92/174 (52%), Gaps = 10/174 (5%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E ++ E + Q++ EK+R+ E E+ EE + E++Q Q+++ Q++ E+ ++ + Sbjct: 433 EEKIRELEEMMQDQEEKLREVE--EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490 Query: 78 MVRGLD---EDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK 134 +++ + E E + + E EK + +EE + +E + ++V + Q+ +K E+ Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550 Query: 135 KLTVKPIETK-NKFSQ-AKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSS 186 ++ ++ +E + K Q A+LL GA + S+ + L P + + K+QE S Sbjct: 551 EVRLQELEERLGKLGQKAELLGGAGRESGSQ---RLPTLTPILQVELKSQEAQS 601 Score = 43.1 bits (100), Expect = 2e-04 Identities = 32/120 (26%), Positives = 64/120 (53%), Gaps = 6/120 (5%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPR-SLYERLQEQKDRKQQEYEEQFKFKNMV 79 E + R QEE W + K + EE E D E+++EQ+++ +++ E+ ++ + + Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376 Query: 80 RGLDEDETNFLDEVSRQQELI---EKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 R DE +E+ RQ+E I E++R+E+ ++ K+ R +K+ +E E+K+ Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436 Score = 42.7 bits (99), Expect = 3e-04 Identities = 37/173 (21%), Positives = 83/173 (47%), Gaps = 19/173 (10%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K E ++ E+ + + EK+R+ E+ EE + E+++EQ ++ Q++ EE Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE--EKIREQDEKIQEQEEE 389 Query: 72 QFKFKNMVRGLDEDETNFL----------DEVSRQQELIEKQRREEELKELKEYRNNLKK 121 ++ + +R +E + DE R+QE E R+EE+++EL+E + Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEEKIRELEEMMQD--- 445 Query: 122 VGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPD 174 +E +EVE+K+ + + + + + + ++ + ++ K LK + Sbjct: 446 ---QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495 Score = 40.8 bits (94), Expect = 0.001 Identities = 33/177 (18%), Positives = 90/177 (50%), Gaps = 9/177 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E+ ++ E+ K+R+ E+ EE + E+++EQ+D+ ++ E+ Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE--EKIREQEDKMWRQEEK 354 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ-----RREEELKELKEYRNNLKKVGISQ 126 + + +R +E +++ Q E I++Q R+EE+++E +E R +K+ + Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ--EKMWRQE 412 Query: 127 ENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + +E ++K+ + E + + + L ++ + + ++++ + E + +E Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469 Score = 39.7 bits (91), Expect = 0.003 Identities = 36/128 (28%), Positives = 69/128 (53%), Gaps = 11/128 (8%) Query: 20 ELDERRKRRQEE-W---EKVRKPEDP--EECPEEVYDPRSLYERLQEQKDRKQQEYEEQF 73 E DE+ + ++EE W EK+R+ E+ E+ + R E+++EQ++ ++ E+ Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 Query: 74 KFKNMVRG----LDEDETNFLDEVSRQQELIEK-QRREEELKELKEYRNNLKKVGISQEN 128 + + M++ L E E +E + QE EK QR+EE+++E +E +K+ +E Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497 Query: 129 KKEVEKKL 136 E E+K+ Sbjct: 498 IWEQEEKM 505 Score = 37.7 bits (86), Expect = 0.010 Identities = 40/187 (21%), Positives = 74/187 (39%), Gaps = 53/187 (28%) Query: 18 EAELDERRKRRQEEWEK---VRKPEDPEECPEEVY------------------------- 49 EA L+ R++R + W++ + + ED ++C E + Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129 Query: 50 DPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDE------------DETNFLDEVSRQQ 97 + +S +++ QE+ + K + ++ K L E +ET D R Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189 Query: 98 ELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK-----------KLTVKPIETKNK 146 IEK +E + L+ YRN + + ++N + EK +L VK + K K Sbjct: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVK--DLKRK 247 Query: 147 FSQAKLL 153 +A+LL Sbjct: 248 LERAQLL 254 Score = 33.9 bits (76), Expect = 0.14 Identities = 32/125 (25%), Positives = 64/125 (51%), Gaps = 20/125 (16%) Query: 16 VSEAELDERRKRRQEE--WEKVRKPEDPEE--CPEEVYDPRSLYERLQEQKDRKQQEYEE 71 V E EL ++QEE W + K ++ EE C +E+ +++EQ+++ ++ E+ Sbjct: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL--------KIREQEEKMWRQEEK 333 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + + +R E E D++ RQ+E I +Q + +E K +R +K+ E +E Sbjct: 334 MHEQEEKIR---EQE----DKMWRQEEKIREQEEKIREQEEKMWRQE-EKIREQDEKIQE 385 Query: 132 VEKKL 136 E+++ Sbjct: 386 QEEEM 390 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 50.1 bits (118), Expect = 2e-06 Identities = 35/139 (25%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Query: 11 IKKRFVSEAELDERRKRR-QEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQE 68 +++++ E EL + ++ +EE EK R+ E +C EE + + L+E+++ R++QE Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135 Query: 69 YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQEN 128 E Q++ + V+ +E E R+QEL + R EEEL++ +E ++ QE Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195 Query: 129 KKEVEKKLTVKPIETKNKF 147 +++ ++ ++ + K ++ Sbjct: 1196 ERQYREEEELQRQKRKQRY 1214 Score = 46.2 bits (108), Expect = 3e-05 Identities = 36/164 (21%), Positives = 80/164 (48%), Gaps = 7/164 (4%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMV 79 +L+E +R Q+E + + + EE E+ + ERLQ++ +QQ EQ + + + Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549 Query: 80 RGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVK 139 L +E L++ R+Q L K+ +EE +L + ++ + +E ++ +E++L + Sbjct: 550 --LKREEEKRLEQERREQRL--KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605 Query: 140 PIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 +E + Q + +K + E + LK + + + + Q+ Sbjct: 606 EVE---RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Score = 46.2 bits (108), Expect = 3e-05 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 9/125 (7%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDP------RSLYERLQEQKDRKQQEYEEQFKF 75 + ++RRQE +K R+ E+ ++ E++ R +ER +KD QQE E+ + Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 + R L E E + +E QQE + E E + +E +K +E ++E E+ Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK---EEELQQEEEQL 1093 Query: 136 LTVKP 140 L +P Sbjct: 1094 LREEP 1098 Score = 46.2 bits (108), Expect = 3e-05 Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 7/152 (4%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYER--LQEQKDRKQQEYEEQFKFKNMV 79 +E+R RRQE K K E C E R +R +E++ +QE + +F+ + Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438 Query: 80 RGLDEDETNFLDEVSR-QQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTV 138 E E FL+E + +QE K R EE+L + +E +++ + ++K +E++ + Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE----QQLHRQERDRKFLEEEQQL 1494 Query: 139 KPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 + E KF + +L + + K E + R Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526 Score = 45.8 bits (107), Expect = 4e-05 Identities = 36/124 (29%), Positives = 66/124 (53%), Gaps = 18/124 (14%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFK 76 E + +ER KRR++E E+ + E+ + EE + L+E+++ R++QE E Q++ Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEE--------QLLREEREKRRRQERERQYRKD 963 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE-----LKEYRNNLKKVGISQENKKE 131 ++ +E E R+QE +K R EEEL++ L+E R ++ QE +++ Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQ 1019 Query: 132 VEKK 135 KK Sbjct: 1020 YRKK 1023 Score = 45.1 bits (105), Expect = 6e-05 Identities = 41/156 (26%), Positives = 74/156 (47%), Gaps = 35/156 (22%) Query: 12 KKRFVSEAEL---------DERRKRRQEEWEKVRKPEDP-----EECPEEVYDPRSLYER 57 +K++ E EL +ER KRR++EWE+ + +D E+ E + R L ER Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046 Query: 58 L------------------QEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQEL 99 +E++ R++QE E Q++ + ++ +E E R+QE Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106 Query: 100 IEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 E+Q REEE EL++ L + + ++E+E++ Sbjct: 1107 -ERQCREEE--ELQQEEEQLLREEREKRRRQELERQ 1139 Score = 44.3 bits (103), Expect = 1e-04 Identities = 33/115 (28%), Positives = 64/115 (55%), Gaps = 7/115 (6%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQ---QEYEEQFK--FK 76 +E++++R+E ++V + E+ +E + R E+LQE++ ++Q QE EEQ + + Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 +R ++E + R+Q+L KQ EEE +E +E R ++ QE ++E Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQ--EEERREQQEERREQQERREQQEERRE 336 Score = 43.5 bits (101), Expect = 2e-04 Identities = 37/167 (22%), Positives = 82/167 (49%), Gaps = 15/167 (8%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFKNMVR 80 +ER KRR++E E+ + E+ + EE + L+E+ + R++QE E Q++ + ++ Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEE--------QLLREEPEKRRRQELERQYREEEELQ 1177 Query: 81 GLDEDETNFLDEVSRQQELIEKQRREEE----LKELKEYRNNLKKVGISQENKKEVEKKL 136 E+E +E ++++ E+Q REEE K + YR+ ++ + + + E E + Sbjct: 1178 --QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + K + ++ + + +S ++ L + + D+ QE Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282 Score = 43.5 bits (101), Expect = 2e-04 Identities = 35/167 (20%), Positives = 80/167 (47%), Gaps = 10/167 (5%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQ-KDRKQQEYEEQFKFKNMVR 80 +E + RRQE +++R D + EE ++L+ Q +DRK +E E+Q + + R Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707 Query: 81 GLDEDETNF----LDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 ++E L+ R++E + ++ +E+L+ + YR L++ + E +++ Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ----- 1762 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 ++ E KF + + L + + S S ++ + + + + +E Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809 Score = 41.6 bits (96), Expect = 7e-04 Identities = 36/125 (28%), Positives = 66/125 (52%), Gaps = 9/125 (7%) Query: 15 FVSEAELDERRK----RRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 F E E + R++ R++EE + +P+ E EE R L ER + +++R+++E + Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL-ERQELRRERQEEEQQ 296 Query: 71 EQ-FKFKNMVRGLDEDETNFLDEVSR-QQELIEKQ--RREEELKELKEYRNNLKKVGISQ 126 +Q + + +R E+E E R QQE E+Q RRE++L+ +E R + + Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356 Query: 127 ENKKE 131 E ++E Sbjct: 357 EERRE 361 Score = 41.2 bits (95), Expect = 9e-04 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 15/101 (14%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 +K+ V E +ERR++R +++ E EE +++ ER Q+Q R+QQE Sbjct: 602 LKREEVERLEQEERREQR------LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE 111 EQ + K +E+E + R+ E++RRE+EL E Sbjct: 656 EQ-RLKR-----EEEEERLEQRLKREH---EEERREQELAE 687 Score = 40.0 bits (92), Expect = 0.002 Identities = 26/117 (22%), Positives = 60/117 (51%), Gaps = 3/117 (2%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E + +E + R+ E E R+ ++ E+ + + + L + +E++ +Q+E EQ + + Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329 Query: 78 MVRGLDEDETNFLDEVSRQQEL---IEKQRREEELKELKEYRNNLKKVGISQENKKE 131 E + E R+Q+L E++RRE++L+ +E +++ Q+ ++E Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 9/132 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPE--EVYDPRSLYERLQEQKDRKQQEY 69 + R + E RR++RQE+ ++ + E+ E E E D + E L Q+ Q+ Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVS-RQQELIEKQR--REEELKELKEYRNNLKKVGISQ 126 E + + + + + F DE R++EL+E +R REE+ ++ +E ++ + + Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV----FQE 240 Query: 127 ENKKEVEKKLTV 138 E +KE K+ TV Sbjct: 241 EEEKEWRKRETV 252 Score = 39.3 bits (90), Expect = 0.003 Identities = 30/119 (25%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 + E +R++ QEE E++RK E E E + + +EQ+ R++QE E + + Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR---EQ 317 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQ--RREEELKELKEYRNNLKKVGISQENKKEVEK 134 ++ E E R+Q+L +Q RRE++L+ +E +++ QE ++ ++ Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376 Score = 39.3 bits (90), Expect = 0.003 Identities = 38/174 (21%), Positives = 77/174 (44%), Gaps = 15/174 (8%) Query: 22 DERRKRRQEEWEK-VRKPEDPEECPEEVYDPRSLYERLQE------QKDRKQQEYEEQFK 74 +ER KRR++E E+ RK + ++ E++ R QE +++ QQE E+ + Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005 Query: 75 FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK 134 + R E E + + QQE + R E E + L+E ++ +E ++ E+ Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE----EEELQQEEE 1061 Query: 135 KLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSSCK 188 +L + ET+ + + L + + + L+ +PE + + C+ Sbjct: 1062 QLLGEERETRRR----QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111 Score = 38.9 bits (89), Expect = 0.004 Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 8/168 (4%) Query: 22 DERRKRRQEEWEK-VRKPEDPEECPEEVYDPRSLYERLQE------QKDRKQQEYEEQFK 74 +ER RR++E E+ RK E+ ++ E++ R QE +++ QQE E+ + Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125 Query: 75 FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY-RNNLKKVGISQENKKEVE 133 + R E E + +E QQE + R E E + +E R ++ + QE ++ + Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKN 181 ++ + E + ++ + + L + + + LK EP+ +N Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233 Score = 38.9 bits (89), Expect = 0.004 Identities = 30/134 (22%), Positives = 68/134 (50%), Gaps = 10/134 (7%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEY-EEQFKFKNMVR 80 +E++ RRQE K R+ E + PE + L E Q + ++Q+++ +E+ + + R Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKF----LEEEQQLHRQQRQRKFLQEEQQLRRQER 1545 Query: 81 GLDEDETNFLDEVSRQQELIEKQRREEELKEL---KEYRNNLKKVGISQENKKEVEKKLT 137 G + D R++E + ++R E++L +++R +KV ++ +K +E + Sbjct: 1546 GQQRRQDR--DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603 Query: 138 VKPIETKNKFSQAK 151 ++ E + + Q + Sbjct: 1604 LRRQEGQQQLRQER 1617 Score = 38.5 bits (88), Expect = 0.006 Identities = 35/129 (27%), Positives = 68/129 (52%), Gaps = 11/129 (8%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE- 70 ++RF+ E E E+R+R++ E EK + + EE EE R ++LQE++D Q++ E Sbjct: 807 EQRFLPEEEEKEQRRRQRREREK--ELQFLEE--EEQLQRRERAQQLQEEEDGLQEDQER 862 Query: 71 ----EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQ 126 EQ + + L+E+ + + L E+ R+E++L L+E L++ + Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL--LQEEEEELQREEREK 920 Query: 127 ENKKEVEKK 135 ++E E++ Sbjct: 921 RRRQEQERQ 929 Score = 38.5 bits (88), Expect = 0.006 Identities = 30/137 (21%), Positives = 69/137 (50%), Gaps = 20/137 (14%) Query: 13 KRFVSEAELDERRKRRQ----------EEWEKVRKPEDPEECPEEVYDPRSLYE----RL 58 ++F E +L + R+ +Q E E++R+ + ++ + D + +E +L Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830 Query: 59 QEQKDRKQQEYEEQFK----FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE 114 +EQ+ R +QE + Q++ F + E++ + +E ++++ E++ REE ++ ++ Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890 Query: 115 YRNNLKKVG--ISQENK 129 ++VG SQE K Sbjct: 1891 EEQRHRQVGEIKSQEGK 1907 Score = 38.1 bits (87), Expect = 0.007 Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 5/117 (4%) Query: 20 ELDERRK----RRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKF 75 E ERR+ RR ++W + + E+ + +Y +L E+L++++ Q+E EE + Sbjct: 858 EDQERRRSQEQRRDQKW-RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEV 132 + R E E + +E QQE + R E E + +E +K Q+ ++++ Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973 Score = 38.1 bits (87), Expect = 0.007 Identities = 29/115 (25%), Positives = 58/115 (50%), Gaps = 7/115 (6%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 L+E ++ RQE K R+ E + EE R +R +++++ + E KF+ Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508 Query: 81 GLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 E E FL+E +Q+L +QR+ + L+E ++ R + Q+ +++ ++K Sbjct: 1509 RSQEPERKFLEE---EQQLHRQQRQRKFLQEEQQLRRQER----GQQRRQDRDRK 1556 Score = 38.1 bits (87), Expect = 0.007 Identities = 39/152 (25%), Positives = 75/152 (49%), Gaps = 22/152 (14%) Query: 21 LDERRKRRQEEWEK-------VRKPEDPEECPEE-----VYDPRSLYERLQEQ-----KD 63 L+E++ RRQE+ K +R+ E ++ +E D + L ER ++Q +D Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642 Query: 64 RKQQEYEEQFKFKNMVRGLDED-ETNFLDEVSRQQELIEKQ-RREEELKELKEYRNNLKK 121 RK E E Q + + + L D + F +E QE E+Q RR+E ++ +E L++ Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702 Query: 122 VGISQENKKEVEKKLTVKPIETKNKFSQAKLL 153 + +K ++++ ++ E + KF + + L Sbjct: 1703 ---QERERKFLQEEQQLRRQELERKFREEEQL 1731 Score = 37.7 bits (86), Expect = 0.010 Identities = 26/97 (26%), Positives = 54/97 (55%), Gaps = 8/97 (8%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRG 81 +ERR++++E E+ + E EE E+ R ER ++Q R+Q+E + + + Sbjct: 312 EERREQQEERREQQERREQQEERREQQLR-REQEERREQQLRREQEEERREQQLRR---- 366 Query: 82 LDEDETNFLDEVSRQQELIEKQ--RREEELKELKEYR 116 +++E ++ R+Q+L +Q RRE++L+ ++ R Sbjct: 367 -EQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402 Score = 37.7 bits (86), Expect = 0.010 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 16/157 (10%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRG 81 ++R KR QEE K E+ E E+ ER ++Q R Q+E + K Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQ--------ERRKQQLKRDQEEERRERWLKLEEEE 495 Query: 82 LDEDETNFLDEVSRQQELIEKQR--REEELKELKEYRNNLKKVGISQEN------KKEVE 133 E + ++ R+QE +QR R+EE + L++ + +++ QE K+E E Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE 555 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 K+L + E + K Q + +K + +KR Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592 Score = 37.7 bits (86), Expect = 0.010 Identities = 32/153 (20%), Positives = 71/153 (46%), Gaps = 21/153 (13%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRG 81 +E++ R+E EK R+ E + EE + LQE++++ + E KF+ Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEE-------QLLQEREEQPLRRQERDRKFREEELR 1368 Query: 82 LDEDETNFLDEVSR------------QQELIEKQRREEELKELKE--YRNNLKKVGISQE 127 E FL+E R +++ + Q RE++L++ ++ +R +++ + Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428 Query: 128 NKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHK 160 ++K E++ V+ E + KF + + +H+ Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461 Score = 37.4 bits (85), Expect = 0.013 Identities = 27/109 (24%), Positives = 63/109 (57%), Gaps = 11/109 (10%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEY--EEQFKF 75 E + +E++++R +++R+ ++ EE E+ + R ER ++Q++R++Q+ E++ + Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQE-EERREQQEERREQQERREQQEERREQQLRREQEERR 347 Query: 76 KNMVRGLDEDETNFL------DEVSRQQELIEKQ--RREEELKELKEYR 116 + +R E+E +E R+Q+L +Q RRE++L+ ++ R Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396 Score = 37.0 bits (84), Expect = 0.017 Identities = 26/106 (24%), Positives = 57/106 (53%), Gaps = 10/106 (9%) Query: 13 KRFVSEAELDERRKRRQEEWEKVRKPEDPEECPE--EVYDPRSLYERLQEQKDRKQQEYE 70 +R E E ++R RR+++ + ++ E E+ E E + R E +EQ+ R++QE Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYR 116 + + + +++E ++ R+Q E++RRE++L+ ++ R Sbjct: 347 REQQLRR-----EQEEERREQQLRREQ---EEERREQQLRREQQLR 384 Score = 37.0 bits (84), Expect = 0.017 Identities = 28/113 (24%), Positives = 57/113 (50%), Gaps = 5/113 (4%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGL 82 E KR ++E + R + EE +++ ER Q++ R+Q+E EQ + V L Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREE--ERRQQRLKREQEERLEQRLKREEVERL 610 Query: 83 DEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +++E E ++E E++RR++ LK ++ +++ Q+ ++E K Sbjct: 611 EQEERR---EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660 Score = 37.0 bits (84), Expect = 0.017 Identities = 34/171 (19%), Positives = 79/171 (46%), Gaps = 18/171 (10%) Query: 11 IKKRFVSEAEL----DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQ 66 ++++F E +L ++ + RRQE + K+ + E EE R +R ++++ + Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR 1780 Query: 67 QEYEEQ--------FKFKNMVRGLDEDETNFLDEVSR------QQELIEKQRREEELKEL 112 QE EEQ KF+ + E E L R ++E ++ + +E+ L++ Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840 Query: 113 KEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSE 163 ++ + ++ +QE + E++L + + + + + KL ++ + E Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891 Score = 36.6 bits (83), Expect = 0.022 Identities = 29/117 (24%), Positives = 61/117 (52%), Gaps = 4/117 (3%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMV 79 E ERR++++E E+ + E EE E+ ER ++Q R+Q+E + + + Sbjct: 323 EQQERREQQEERREQQLRREQ-EERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381 Query: 80 RGLDEDETNFLDEVSRQQELIEKQ--RREEELKELKEYRNNLKKVGISQENKKEVEK 134 + E + ++ R+Q+L +Q RRE++L+ ++ R +++ QE ++ +K Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQEEERHEQK 437 Score = 36.6 bits (83), Expect = 0.022 Identities = 26/120 (21%), Positives = 60/120 (50%), Gaps = 4/120 (3%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R E +++ +R QEE + + + EE E R E +EQ+ R++Q+ Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + + + + E + ++ R+Q+L RRE++L+ ++ R ++ Q++++E Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQL----RREQQLRREQQLRREQEEERHEQKHEQE 441 Score = 36.6 bits (83), Expect = 0.022 Identities = 32/143 (22%), Positives = 71/143 (49%), Gaps = 10/143 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQ-EYE 70 ++R + ++ +RR+++ + ++ ++ E R R ++Q R+QQ E Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELK-ELKEYRNNLKKVGISQENK 129 +Q + + +R E+E R ++ E++RRE+ LK E +E R+ LK+ ++ ++ Sbjct: 417 QQLRREQQLRREQEEE--------RHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468 Query: 130 KEVEKKLTVKPIETKNKFSQAKL 152 +E K+ + E + + KL Sbjct: 469 QERRKQQLKRDQEEERRERWLKL 491 Score = 36.6 bits (83), Expect = 0.022 Identities = 30/126 (23%), Positives = 63/126 (50%), Gaps = 10/126 (7%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R + L E+R+R+ E R+ + PEE + +R + +K+ + E EE Sbjct: 781 RQRLSARPPLREQRERQLRAEE--RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELK-----ELKEYRNNL-KKVGIS 125 Q + + + L E+E ++ R++ ++QRR+++ + E K R+ L K + Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRS--QEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896 Query: 126 QENKKE 131 ++ +KE Sbjct: 897 EQLRKE 902 Score = 36.6 bits (83), Expect = 0.022 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 10/126 (7%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVY-------DPRSLYERLQEQKDRKQQEYEEQFK 74 +ER KRR +E E+ + E+ + EE R ER +++ QQE E+ + Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095 Query: 75 FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEK 134 + R E E +E QQE + R E E + +E ++ +E ++E E+ Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE---EEEVQQEEEQ 1152 Query: 135 KLTVKP 140 L +P Sbjct: 1153 LLREEP 1158 Score = 36.2 bits (82), Expect = 0.028 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 19/135 (14%) Query: 20 ELDERRKRRQEEWE-KVRKPEDPEECP-EEVYDPRSLYERLQEQKDRKQQ---------- 67 E ER +RR EE + + K + EE P EE R L E ++ ++ KQQ Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238 Query: 68 --EYEEQFKFKNMV-----RGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLK 120 E E++++ + V L E+E E+ ++E + K R+E +E +E + Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298 Query: 121 KVGISQENKKEVEKK 135 ++ Q+ +++ E++ Sbjct: 299 RLRREQQLRRKQEEE 313 Score = 36.2 bits (82), Expect = 0.028 Identities = 30/130 (23%), Positives = 66/130 (50%), Gaps = 11/130 (8%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 + E D ++RR+ + PE+ + EE + + + QE+K ++E EE+ + + Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLT 137 R E+E L E R+++ + +Q R+ + +E +E R+ ++ +K +E++ Sbjct: 1334 TDRKFREEE-QLLQE--REEQPLRRQERDRKFRE-EELRH-------QEQGRKFLEEEQR 1382 Query: 138 VKPIETKNKF 147 ++ E + KF Sbjct: 1383 LRRQERERKF 1392 Score = 35.8 bits (81), Expect = 0.037 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 10/122 (8%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R E + E + +QEE + +R+ + E ER Q +KD+K Q+ EE Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER--------ER-QYRKDKKLQQKEE 971 Query: 72 QFKFKN-MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKK 130 Q + R E E + +E QQE + R E E + +E+ +K Q+ ++ Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031 Query: 131 EV 132 ++ Sbjct: 1032 QL 1033 Score = 35.8 bits (81), Expect = 0.037 Identities = 27/115 (23%), Positives = 61/115 (53%), Gaps = 2/115 (1%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEE-VYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 +E++ RRQE ++ R+ D + EE + R + ++++DRK + E++ + + R Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595 Query: 81 GLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 EDE + +QQ E+ R+ E ++L + R +++ + ++K +E++ Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE-QQLHRQERDRKFLEEE 1649 Score = 35.0 bits (79), Expect = 0.063 Identities = 37/120 (30%), Positives = 62/120 (51%), Gaps = 11/120 (9%) Query: 20 ELDERRK---RRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFK 76 E +ERR +R+EE + R + EE E+ R ERL++++ R+Q+ E+ + + Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRL-KREEVERLEQEERREQRLKREEPEEE 628 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQ--RREEELK-ELKEYRNNLKKVGISQENKKEVE 133 + L +E E RQQ+L +Q RRE+ LK E +E R + +E ++E E Sbjct: 629 RRQQLLKSEE----QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684 Score = 34.3 bits (77), Expect = 0.11 Identities = 28/116 (24%), Positives = 64/116 (55%), Gaps = 7/116 (6%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGL 82 E++ RR+++ + ++ ++ E + R +E+ EQ+ R+Q+ EQ + ++ ++ Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEER--HEQKHEQERREQRLKREQEERRDWLK-- 459 Query: 83 DEDETNFLDEVSRQQEL---IEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 E+ET ++ R+Q+L E++RRE LK +E R ++ Q +++ E++ Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515 Score = 33.9 bits (76), Expect = 0.14 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 21/116 (18%) Query: 20 ELDERRKRRQEEW-------EKVRKP-----EDPEECPEEVYDPRSLYE--RLQEQKDRK 65 +L+E RKRR+ E++RK E+ EE E + R E R ++++ Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936 Query: 66 QQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQ-------ELIEKQRREEELKELKE 114 QQE E+ + + R E E + + QQ E EK+RR+E K+ +E Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992 Score = 33.5 bits (75), Expect = 0.18 Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 + + S E ++RRQE+ EK R+ E + EE + + QE++ R+ ++ Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE----ERAHRQQQEEEQRRDFTWQW 771 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 Q + K+ RG R+++L ++R++ E + L E ++ +E +KE Sbjct: 772 QAEEKS-ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830 Query: 132 VE 133 ++ Sbjct: 831 LQ 832 Score = 28.5 bits (62), Expect = 5.9 Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 11/116 (9%) Query: 10 IIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEY 69 ++K E + R+ +QE E+ K E+ EE E+ R E +E+++++ E Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ----RLKREHEEERREQELAEE 688 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELI-------EKQRREEELKELKEYRNN 118 E++ + + + + + E +Q + E QRR +E +E + R + Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 6/118 (5%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 E + RRQEE WEK K EE E + E + +K+ K +E EE+ + +R Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407 Query: 81 GLDE---DETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGISQENKKEVEK 134 +E +E ++ RQ++ + R+EE+++E +E R KK+ +E E EK Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465 Score = 47.8 bits (112), Expect = 9e-06 Identities = 36/127 (28%), Positives = 68/127 (53%), Gaps = 7/127 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E+ ++RQE+ EK+ K E+ EE + R QE+K R+Q+E + Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ-RREEELKEL-KEYRNNLKKVGISQENK 129 + + K + E E ++ + QE E R+EE+++E K+ R +K+ +E Sbjct: 644 EQEEK-----MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698 Query: 130 KEVEKKL 136 +E E+K+ Sbjct: 699 QEQEEKM 705 Score = 47.4 bits (111), Expect = 1e-05 Identities = 30/123 (24%), Positives = 71/123 (57%), Gaps = 4/123 (3%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E ++ QE+ EK+R+ E E+ E+ R E + E++++ +++ E Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 ++ + +R +E +++ RQ+E++ +EE+++EL+E + +K+ +E ++E Sbjct: 358 MWEKEEKMRRQEEMMWEKEEKMRRQEEMM--WEKEEKIRELEEKMHEQEKIREQEEKRQE 415 Query: 132 VEK 134 EK Sbjct: 416 EEK 418 Score = 46.2 bits (108), Expect = 3e-05 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 13/120 (10%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 E + RRQEE WEK K EE E + E + +K+ K + EE K Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK---- 389 Query: 81 GLDEDETNFLDEVSRQQELI----EKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 E++ L+E +QE I EK++ EE+++E ++ + K+ +E +E E+K+ Sbjct: 390 ---EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446 Score = 44.3 bits (103), Expect = 1e-04 Identities = 43/187 (22%), Positives = 96/187 (51%), Gaps = 18/187 (9%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPED-----PEECPEEVYDPRSLYERL--QEQKDR 64 +++ + E+ ++++ E+ EK+RK E+ E+ E+ R E++ QE+K R Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541 Query: 65 KQQE-YEEQFKFKNMVRGLDEDETNFL-DEVSRQQELIEKQ-----RREEELKELKEYRN 117 +Q+E + E+ K + +E++ D++ RQ+E I +Q R+EE+++E +E R Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601 Query: 118 NLKKVGISQENK-KEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPE 176 ++ QE K +E E+K+ + + + + + + + + + G +++ E Sbjct: 602 EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM---CE 658 Query: 177 PDDKNQE 183 ++K QE Sbjct: 659 QEEKMQE 665 Score = 43.5 bits (101), Expect = 2e-04 Identities = 32/138 (23%), Positives = 72/138 (52%), Gaps = 16/138 (11%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +++ + ++ E KR+++E + R+ E E E+V+ E+++EQ++++Q++ E+ Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE---EKIREQEEKRQEQEEK 606 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQR------------REEELKELKEYRNNL 119 +K + +R +E +++ Q+E I +Q +EE++ E +E Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666 Query: 120 KKVGISQENK-KEVEKKL 136 ++ QE K +E EKK+ Sbjct: 667 EETMWRQEEKIREQEKKI 684 Score = 42.4 bits (98), Expect = 4e-04 Identities = 31/125 (24%), Positives = 68/125 (54%), Gaps = 14/125 (11%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +KR EA++ + ++ +E+ EK+R+ E EE ++E+ + +++ K+QE EE Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE-----KIHEQEKIREEEKRQEQEE 477 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 ++ E++ + +E+ RQ+E + +Q + +E K +R +K+ +E +E Sbjct: 478 MWR--------QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE-EKIREQEEKIRE 528 Query: 132 VEKKL 136 E+K+ Sbjct: 529 QEEKM 533 Score = 42.0 bits (97), Expect = 5e-04 Identities = 27/119 (22%), Positives = 68/119 (57%), Gaps = 10/119 (8%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E ++ E+ ++ +E+ EK+R+ E+ + EE + E++ EQ+++ Q++ E ++ + Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE--EKMCEQEEKMQEQEETMWRQEE 675 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 +R ++ +++ Q+E++++Q EE++ E +E K+ +E +E E+K+ Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQ--EEKMWEQEE------KMCEQEEKMQEQEEKM 726 Score = 41.2 bits (95), Expect = 9e-04 Identities = 30/128 (23%), Positives = 72/128 (56%), Gaps = 9/128 (7%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLY---ERLQEQKDRKQQE 68 KK + E ++ E+ K R+EE K ++ E+ E++++ ++ E++ EQ+++ +++ Sbjct: 451 KKMWRQEEKIHEQEKIREEE--KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508 Query: 69 YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQEN 128 E+ ++ + +R +E +++ RQ+E K R +EE+ +E + +K+ +E Sbjct: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEE---KIREQEEMWREEEKMHEQEKIW-EEEK 564 Query: 129 KKEVEKKL 136 ++E E K+ Sbjct: 565 RQEQEDKM 572 Score = 39.3 bits (90), Expect = 0.003 Identities = 29/150 (19%), Positives = 74/150 (49%), Gaps = 8/150 (5%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDR------KQQEYEEQFKF 75 +E+R+ ++E W + K + EE + E++++Q+++ K +E EE+ + Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRR--EEELKELKEYRNNLKKVGISQENKKEVE 133 + E++ +E+ R++E + +Q + EEE ++ +E + ++ I ++ +K Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSE 163 ++ ++ E K + + K+ K + E Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQE 618 Score = 35.4 bits (80), Expect = 0.048 Identities = 36/166 (21%), Positives = 67/166 (40%), Gaps = 14/166 (8%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 +AE D K Q K++ + E L+ RL +Q++ K EE K + Sbjct: 264 QAEADHLGKELQSVSAKLQAQVEENE----------LWNRLNQQQEEKMWRQEE--KIQE 311 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLT 137 + E E ++ + +E EK RR+EE+ KE +++ K+E ++ Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKMRRQE 369 Query: 138 VKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 E + K + + + + K E + + E ++K QE Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 415 Score = 33.9 bits (76), Expect = 0.14 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 9/108 (8%) Query: 18 EAELDERRKRRQEEWEKVRKPEDP-----EECPEEVYDPRSLYERLQEQ--KDRKQQE-- 68 E ++ E+ + QE+ EK+ + E+ E+ E+ E+++EQ K R+Q+E Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691 Query: 69 YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYR 116 E++ + + E E ++ + QE EK RR+EE +E R Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/118 (30%), Positives = 59/118 (50%), Gaps = 6/118 (5%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 E + RRQEE WEK K EE E + E + +K+ K +E EE+ + +R Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393 Query: 81 GLDE---DETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGISQENKKEVEK 134 +E +E ++ RQ++ + R+EE+++E +E R KK+ +E E EK Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 451 Score = 47.0 bits (110), Expect = 2e-05 Identities = 33/132 (25%), Positives = 75/132 (56%), Gaps = 8/132 (6%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE-- 68 ++++ + ++ E+ ++RQEE EK+R+ E +E +++ R QE+K R+Q++ Sbjct: 382 LEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKI-REQEEKIREQEKKM 439 Query: 69 YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ----RREEELKELKEYRNNLKKVGI 124 + ++ K + +E++ +E+ RQ+E I +Q R++E++ E ++ R +KV Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR 499 Query: 125 SQENKKEVEKKL 136 +E + E+K+ Sbjct: 500 QEEKMHDQEEKI 511 Score = 46.6 bits (109), Expect = 2e-05 Identities = 36/131 (27%), Positives = 68/131 (51%), Gaps = 10/131 (7%) Query: 16 VSEAELDERRKRRQEEWEKVRKPED-----PEECPEEVYDPRSLYERL--QEQKDRKQQE 68 + E E R+K + E EK+RK E+ E+ ++ R E++ QE+K R+Q+E Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530 Query: 69 --YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGIS 125 E++ K + + E E ++ + QE + +R+EE+++E +E R +K+ Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590 Query: 126 QENKKEVEKKL 136 +E E E+K+ Sbjct: 591 EEKIWEQEEKI 601 Score = 45.4 bits (106), Expect = 5e-05 Identities = 35/133 (26%), Positives = 71/133 (53%), Gaps = 8/133 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--Y 69 +K + E ++ E ++ QE+ EK+R+ E+ EE + +E+K R+Q+E + Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359 Query: 70 EEQFKFKNMVRGLDEDETNF--LDEVSRQQELI----EKQRREEELKELKEYRNNLKKVG 123 E++ K + + + E E L+E +QE I EK++ EE+++E ++ + K+ Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419 Query: 124 ISQENKKEVEKKL 136 +E +E E+K+ Sbjct: 420 RQEEKIREQEEKI 432 Score = 44.7 bits (104), Expect = 8e-05 Identities = 41/178 (23%), Positives = 89/178 (50%), Gaps = 17/178 (9%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +KR EA++ + ++ +E+ EK+R+ E EE ++E+ + +++ K+QE EE Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE-----KIHEQEKIREEEKRQEQEE 463 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ-----RREEELKELKE-YRNNLKKVGIS 125 ++ + +R +++E E +QE I KQ R+EE++ + +E R +K+ Sbjct: 464 MWRQEEKIR--EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521 Query: 126 QENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 +E +E E+K+ E + K + + + + K E ++ + ++K +E Sbjct: 522 EEKIREQEEKIR----EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575 Score = 42.0 bits (97), Expect = 5e-04 Identities = 33/155 (21%), Positives = 76/155 (49%), Gaps = 5/155 (3%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDP-EECPEEVYDPRSLYERLQEQKDRKQQEYE 70 +K E ++ E+ ++ + EK+R+ E+ E E++ + + + +E+ ++++ + Sbjct: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEK-QRREEELKELKEYRNNLKKVGISQENK 129 EQ K + + E E ++ + +E EK +EE+++E +E ++ QE K Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621 Query: 130 K-EVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSE 163 E E+K+ + E K + + K+ V+ + E Sbjct: 622 MCEQEEKMQEQ--EEKMRRQEEKMWEQEVRLRQQE 654 Score = 38.9 bits (89), Expect = 0.004 Identities = 34/116 (29%), Positives = 62/116 (53%), Gaps = 7/116 (6%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E ++ E+ K R++E EK+R+ E E+ E+ R E++ EQ++ K +E EE + Sbjct: 557 EEKMQEQEKMRRQE-EKIREQE--EKIREQKEKIREQEEKIWEQEE-KIREQEEM--MQE 610 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVE 133 + E E ++ + QE EK RR+EE +E R ++ + QE+++ +E Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM-QEHQEHLE 665 Score = 34.7 bits (78), Expect = 0.082 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 17/119 (14%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 +AE D K Q K++ + E L+ RL +Q++ K EE K + Sbjct: 264 QAEADHLGKELQSVSAKLQAQVEENE----------LWNRLNQQQEEKMWRQEE--KIQE 311 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + E E ++ + +E EK RR+EE+ KE +K+ +E E E+K+ Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-----EKMRRQEEMMWEKEEKM 365 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 49.7 bits (117), Expect = 2e-06 Identities = 50/209 (23%), Positives = 90/209 (43%), Gaps = 21/209 (10%) Query: 40 DPEECPEEVYDPRSLY--ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQ 97 DPEE + + R L +R +E+++R++QE E+ K + + + + E+ T +E SR+ Sbjct: 475 DPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRL 534 Query: 98 ELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAV 157 E + + +EE+L+ E R + ++E E+ K E + + ++ Sbjct: 535 EAEQAREKEEQLQRQAEER--------ALREREEAERAQRQKEEEARVREEAERVRQERE 586 Query: 158 KHKSSESGNSVKRLK---------PDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVC 208 KH E ++R K E DK + +L+G + SA C Sbjct: 587 KHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTE--VSALPC 644 Query: 209 IGILPGLGAYSGSSDSESSSDSEGTINAT 237 PG G GS +S S+ T+ +T Sbjct: 645 TTNAPGNGKPVGSPHVVTSHQSKVTVEST 673 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 48.9 bits (115), Expect = 4e-06 Identities = 33/122 (27%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 16 VSEAELDERRKRRQEE--WEKVRKPEDPEECPEEVYDP-RSLYERLQEQKDRKQQEYEEQ 72 V E EL R ++QEE W + K ++ EE +E + R E+++EQ+++ +++ E Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405 Query: 73 FKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEV 132 ++ + +R +E +++ RQ+E++ + +EE+++EL+E + +K+ +E ++E Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWE--KEEKIRELEEKMHEQEKIREQEEKRQEE 463 Query: 133 EK 134 EK Sbjct: 464 EK 465 Score = 48.1 bits (113), Expect = 7e-06 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 6/118 (5%) Query: 23 ERRKRRQEE--WEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 E + RRQEE WEK K EE E + E + +K+ K +E EE+ + +R Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454 Query: 81 GLDE---DETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGISQENKKEVEK 134 +E +E ++ RQ++ + R+EE+++E +E R +K+ +E E EK Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512 Score = 45.8 bits (107), Expect = 4e-05 Identities = 35/131 (26%), Positives = 73/131 (55%), Gaps = 12/131 (9%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +KR EA++ + ++ +E+ EK+R+ E+ EE ++E+ + +++ K+QE EE Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE-----KIHEQEKIREEEKRQEQEE 524 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQ-----RREEELKELKE-YRNNLKKVGIS 125 ++ + +R E+ +++ Q+E I KQ R+EE++ + +E R +KV Sbjct: 525 MWRQEEKIRE-QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583 Query: 126 QENKKEVEKKL 136 +E +E E+K+ Sbjct: 584 EEKIREQEEKI 594 Score = 45.4 bits (106), Expect = 5e-05 Identities = 34/133 (25%), Positives = 70/133 (52%), Gaps = 8/133 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEY-- 69 +K + E ++ E ++ QE+ EK+R+ E+ EE + +E+K R+Q+E Sbjct: 361 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420 Query: 70 --EEQFKFKNMVRGLDEDETNFLDEVSRQQELI----EKQRREEELKELKEYRNNLKKVG 123 EE+ + + + E++ L+E +QE I EK++ EE+++E ++ + K+ Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480 Query: 124 ISQENKKEVEKKL 136 +E +E E+K+ Sbjct: 481 RQEEKIREQEEKI 493 Score = 45.4 bits (106), Expect = 5e-05 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYE---RLQEQKDRKQQE 68 +K + E E ++ RK+ ++ W + K D EE E + E R QE+K R+Q+E Sbjct: 541 QKEKIHEQE-EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599 Query: 69 --YEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEE--LKELKEYRNNLKKVGI 124 E++ + + E E ++ + QE EK RR+EE ++ K+ R +K+ Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659 Query: 125 SQENKKEVEKKL 136 +E +E E+K+ Sbjct: 660 QEEMMQEQEEKM 671 Score = 43.9 bits (102), Expect = 1e-04 Identities = 44/179 (24%), Positives = 87/179 (48%), Gaps = 26/179 (14%) Query: 22 DERRKRRQEEW---EKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--YEEQFKFK 76 +E+R+ ++E W EK+R+ E+ E++++ QE+K RKQ+E + ++ K Sbjct: 516 EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE--------QEEKIRKQEEKMWRQEEKMH 567 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQ-----RREEELKELKEY-RNNLKKVGISQENKK 130 + + E E ++V RQ+E I +Q +EE+++E +E + +K+G +E Sbjct: 568 DQEEKIREQE----EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623 Query: 131 EVEKKLTVKPIETKNKFSQAKLLAGAVK-HKSSESGNSVKRLKPDPEPDDKNQEPSSCK 188 E E+K+ + E K + + K+ K + E + + + E QE C+ Sbjct: 624 EQEEKMQEQ--EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680 Score = 42.4 bits (98), Expect = 4e-04 Identities = 31/133 (23%), Positives = 75/133 (56%), Gaps = 9/133 (6%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDP----RSLYERLQEQKD--- 63 ++++ + ++ E+ ++RQEE EK+R+ E +E +++ R E+++EQ++ Sbjct: 443 LEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501 Query: 64 RKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVG 123 R++++ EQ K + + +++E +E R+QE I +Q+ + +E ++ R +K+ Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE-EKIRKQEEKMW 560 Query: 124 ISQENKKEVEKKL 136 +E + E+K+ Sbjct: 561 RQEEKMHDQEEKI 573 Score = 40.4 bits (93), Expect = 0.002 Identities = 35/148 (23%), Positives = 74/148 (50%), Gaps = 8/148 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E+ ++ +E+ EK+R+ E+ + EE + E++ EQ++ K QE EE Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE--EKMCEQEE-KMQEQEE 634 Query: 72 QF-----KFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQ 126 + K + + + E E ++ QE EK +EE +E + ++ + + Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694 Query: 127 ENKKEVEKKLTVKPIETKNKFSQAKLLA 154 + +K E+++ ++ E K + Q L A Sbjct: 695 QEEKMWEQEVRLRQQEEKMQEHQEHLEA 722 Score = 34.7 bits (78), Expect = 0.082 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 17/119 (14%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 +AE D K Q K++ + E L+ RL +Q++ K EE K + Sbjct: 325 QAEADHLGKELQSVSAKLQAQVEENE----------LWNRLNQQQEEKMWRQEE--KIQE 372 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + E E ++ + +E EK RR+EE+ KE +K+ +E E E+K+ Sbjct: 373 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE-----EKMRRQEEMMWEKEEKM 426 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 48.5 bits (114), Expect = 6e-06 Identities = 39/133 (29%), Positives = 73/133 (54%), Gaps = 9/133 (6%) Query: 12 KKRFVSEAELDER-RKRRQEEWEKVRKPE--DPEECPEEVYDPRSLYERLQEQKDRKQQE 68 KK SE + + R R++R+ E EK RK E E+ E + R +R +E+++++ +E Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111 Query: 69 YEEQFKFKNMVRGLDEDETNFLD--EVSRQQELIEKQRREEELKELKEYRNNLKK----V 122 E++ K + RG E + E +++E E++R++EE ++ +E + K+ V Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171 Query: 123 GISQENKKEVEKK 135 G +E +KE E+K Sbjct: 172 GEKEEERKEKERK 184 Score = 47.0 bits (110), Expect = 2e-05 Identities = 36/141 (25%), Positives = 72/141 (51%), Gaps = 5/141 (3%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K+ + E ER+KRR+E+ K + E+ E+ ++ R + ++++RK++ E Sbjct: 85 EKKGERKKEERERKKRRREKENK--EGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELI---EKQRREEELKELKEYRNNLKKVGISQEN 128 + K + + E E + R+++ + E++R+E+E KE K+ N K+ +E Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202 Query: 129 KKEVEKKLTVKPIETKNKFSQ 149 K+ E+K K E + K Q Sbjct: 203 KERRERKKERKKKEERKKERQ 223 Score = 41.2 bits (95), Expect = 9e-04 Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 7/129 (5%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGL 82 ER+K +E ++ R+ E+ E +E + ER + K+ K++E +E+ R Sbjct: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE-------RKR 141 Query: 83 DEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIE 142 +E + + R++E K+R++ E K++ E K+ + K+E +K K E Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201 Query: 143 TKNKFSQAK 151 K + + K Sbjct: 202 RKERRERKK 210 Score = 40.0 bits (92), Expect = 0.002 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 8/125 (6%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 I+ R + E + RK+ + E EK RK E +E E ER +E+++RK++ E Sbjct: 45 IETRKEGKKERESERKKERREREK-RKREREKERKRERGKKEKKGERKKEERERKKRRRE 103 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKK 130 ++ K + E S++ + E++R+EE +E ++ R K +E +K Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGK--ERERKEERKREERKERERKK-----EEREK 156 Query: 131 EVEKK 135 E E+K Sbjct: 157 ERERK 161 Score = 32.3 bits (72), Expect = 0.41 Identities = 31/153 (20%), Positives = 68/153 (44%), Gaps = 4/153 (2%) Query: 33 EKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDE 92 E+ R+ E +E +E R R +E++ R++++ ++ + K +G + E + Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER--ER 97 Query: 93 VSRQQELIEKQRREEELKELKE--YRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQA 150 R++E K+ E+E ++ KE R K G +E K+E +++ + K + + Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157 Query: 151 KLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + K + + G + K + K +E Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRE 190 Score = 30.4 bits (67), Expect = 1.6 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 12/105 (11%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQ--KDRKQQEY 69 K+ E E ER+KR +++ + + +E E R+ ER +E+ K+R++++ Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE 114 E + K +E + RQ EK+R + E KE K+ Sbjct: 211 ERKKK----------EERKKERQKDRQTNWREKERGKRERKERKK 245 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 47.8 bits (112), Expect = 9e-06 Identities = 38/147 (25%), Positives = 76/147 (51%), Gaps = 16/147 (10%) Query: 18 EAELDERR------KRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 + E +ERR K+++EE E++RK + + E+ R ER +++R++QE E Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER--REQERREQERRE 709 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 Q + + R L E E R+QE ++ +R +E ++ + + + ++ KKE Sbjct: 710 QER-REQERQLAEQERR------REQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 762 Query: 132 VEKKLTVKPIETKNKFSQAKLLAGAVK 158 +++L + ++ + + +AK AGA K Sbjct: 763 EQQRLAERQLQEEQE-KKAKEAAGASK 788 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 7/110 (6%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDP--RSLYERLQEQKDRKQQEYEEQFKF 75 E E E+ +R QE E+ R+ ++ E ++ + R ERLQ +++ +++E + + Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGIS 125 + + R L+E + QQ L E+Q +EE+ K+ KE K + ++ Sbjct: 749 EQLQRELEEKKKK-----EEQQRLAERQLQEEQEKKAKEAAGASKALNVT 793 Score = 36.2 bits (82), Expect = 0.028 Identities = 33/168 (19%), Positives = 75/168 (44%), Gaps = 15/168 (8%) Query: 24 RRKRRQEEWEKVRKPEDPEECPEEVYDPR--------SLYERLQEQKDRKQQEYEEQFKF 75 RRK E+ + + ED EEV R ER+++ K+ K+++ E++F Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF-- 603 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +++T E +E +K+ ++++E++ R ++ + ++E E++ Sbjct: 604 -----AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658 Query: 136 LTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + ++ K + Q +L A + +E +R + E + + QE Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 706 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 47.8 bits (112), Expect = 9e-06 Identities = 38/147 (25%), Positives = 76/147 (51%), Gaps = 16/147 (10%) Query: 18 EAELDERR------KRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 + E +ERR K+++EE E++RK + + E+ R ER +++R++QE E Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER--REQERREQERRE 705 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 Q + + R L E E R+QE ++ +R +E ++ + + + ++ KKE Sbjct: 706 QER-REQERQLAEQERR------REQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758 Query: 132 VEKKLTVKPIETKNKFSQAKLLAGAVK 158 +++L + ++ + + +AK AGA K Sbjct: 759 EQQRLAERQLQEEQE-KKAKEAAGASK 784 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 7/110 (6%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDP--RSLYERLQEQKDRKQQEYEEQFKF 75 E E E+ +R QE E+ R+ ++ E ++ + R ERLQ +++ +++E + + Sbjct: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGIS 125 + + R L+E + QQ L E+Q +EE+ K+ KE K + ++ Sbjct: 745 EQLQRELEEKKKK-----EEQQRLAERQLQEEQEKKAKEAAGASKALNVT 789 Score = 36.2 bits (82), Expect = 0.028 Identities = 33/168 (19%), Positives = 75/168 (44%), Gaps = 15/168 (8%) Query: 24 RRKRRQEEWEKVRKPEDPEECPEEVYDPR--------SLYERLQEQKDRKQQEYEEQFKF 75 RRK E+ + + ED EEV R ER+++ K+ K+++ E++F Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF-- 599 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +++T E +E +K+ ++++E++ R ++ + ++E E++ Sbjct: 600 -----AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654 Query: 136 LTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 + ++ K + Q +L A + +E +R + E + + QE Sbjct: 655 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 702 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 46.6 bits (109), Expect = 2e-05 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 17/166 (10%) Query: 21 LDERRKRRQE----EWEKVRKPEDPEECPEEVYDPRSLY-----ERLQEQKDRKQQEYEE 71 +D RK+R E E+E E+ EE PE+ +P S+ L+ R QQE +E Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE----LKEYRNNLKKVGISQE 127 + + + L E + +E RQ L E+Q+R E+ KE L+E + ++ QE Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQL-LAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424 Query: 128 ---NKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 ++E E+K ++ +E + K + + A K + ++R Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470 Score = 39.3 bits (90), Expect = 0.003 Identities = 26/93 (27%), Positives = 50/93 (53%), Gaps = 13/93 (13%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 L ER+KR +++ E+ R+ E+ + E R Q++++++++E EE+ + + + R Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREA--------RRQQEREQRRREQEEKRRLEELER 443 Query: 81 GLDEDETNFLDE-----VSRQQELIEKQRREEE 108 E+E E V R+QE I +Q EE+ Sbjct: 444 RRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQ 476 Score = 38.9 bits (89), Expect = 0.004 Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 11/105 (10%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R + E + ER RRQ+E E+ R+ ++ + EE L R +E+++R++ E E Sbjct: 405 QRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE------LERRRKEEEERRRAEEE- 457 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYR 116 K V E L+E R E++++Q +E+ L ++R Sbjct: 458 ----KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHR 498 Score = 38.1 bits (87), Expect = 0.007 Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 14/170 (8%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYER---LQEQKDRKQQEYEEQFKFKN 77 L + K R E + + ++ + +E Y + L ER +++QK+++++ E+Q + + Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRERE 418 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQE--NKKEVEKK 135 R + ++ E R+ E +E++R+EEE E + ++V QE ++ E++ Sbjct: 419 ARRQQEREQRRREQEEKRRLEELERRRKEEE--ERRRAEEEKRRVEREQEYIRRQLEEEQ 476 Query: 136 LTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPS 185 ++ ++ + QA LL H+ +S + P P + +PS Sbjct: 477 RHLEVLQQQLLQEQAMLLH---DHRRPHPQHS----QQPPPPQQERSKPS 519 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 46.6 bits (109), Expect = 2e-05 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 17/166 (10%) Query: 21 LDERRKRRQE----EWEKVRKPEDPEECPEEVYDPRSLY-----ERLQEQKDRKQQEYEE 71 +D RK+R E E+E E+ EE PE+ +P S+ L+ R QQE +E Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE----LKEYRNNLKKVGISQE 127 + + + L E + +E RQ L E+Q+R E+ KE L+E + ++ QE Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQL-LAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424 Query: 128 ---NKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 ++E E+K ++ +E + K + + A K + ++R Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470 Score = 43.5 bits (101), Expect = 2e-04 Identities = 54/229 (23%), Positives = 96/229 (41%), Gaps = 16/229 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R + E + ER RRQ+E E+ R+ ++ + EE L R +E+++R++ E E Sbjct: 405 QRRRLEEQQRREREARRQQEREQRRREQEEKRRLEE------LERRRKEEEERRRAEEE- 457 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 K V E L+E R E++++Q +E+ L ++R + ++ Sbjct: 458 ----KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQ 513 Query: 132 VEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPSSCKSLG 191 K + E K + A +S S +R D Q+ S Sbjct: 514 ERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSPVLSRR---DSPLQGSGQQNSQAGQRN 570 Query: 192 NTSLSGPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSE-GTINATGK 239 +TS P + + PG G+ SGSS+S S S G+ + +G+ Sbjct: 571 STSSIEPRLLWERVEKLVP-RPGSGSSSGSSNSGSQPGSHPGSQSGSGE 618 Score = 39.3 bits (90), Expect = 0.003 Identities = 26/93 (27%), Positives = 50/93 (53%), Gaps = 13/93 (13%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 L ER+KR +++ E+ R+ E+ + E R Q++++++++E EE+ + + + R Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREA--------RRQQEREQRRREQEEKRRLEELER 443 Query: 81 GLDEDETNFLDE-----VSRQQELIEKQRREEE 108 E+E E V R+QE I +Q EE+ Sbjct: 444 RRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQ 476 Score = 38.1 bits (87), Expect = 0.007 Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 14/170 (8%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYER---LQEQKDRKQQEYEEQFKFKN 77 L + K R E + + ++ + +E Y + L ER +++QK+++++ E+Q + + Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRERE 418 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQE--NKKEVEKK 135 R + ++ E R+ E +E++R+EEE E + ++V QE ++ E++ Sbjct: 419 ARRQQEREQRRREQEEKRRLEELERRRKEEE--ERRRAEEEKRRVEREQEYIRRQLEEEQ 476 Query: 136 LTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPS 185 ++ ++ + QA LL H+ +S + P P + +PS Sbjct: 477 RHLEVLQQQLLQEQAMLLH---DHRRPHPQHS----QQPPPPQQERSKPS 519 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 46.6 bits (109), Expect = 2e-05 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 17/166 (10%) Query: 21 LDERRKRRQE----EWEKVRKPEDPEECPEEVYDPRSLY-----ERLQEQKDRKQQEYEE 71 +D RK+R E E+E E+ EE PE+ +P S+ L+ R QQE +E Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKE----LKEYRNNLKKVGISQE 127 + + + L E + +E RQ L E+Q+R E+ KE L+E + ++ QE Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQL-LAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424 Query: 128 ---NKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 ++E E+K ++ +E + K + + A K + ++R Sbjct: 425 REQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRR 470 Score = 44.7 bits (104), Expect = 8e-05 Identities = 41/172 (23%), Positives = 85/172 (49%), Gaps = 20/172 (11%) Query: 21 LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVR 80 L ER+KR +++ E+ R+ E+ + E R Q++++++++E EE+ + + + R Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREA--------RRQQEREQRRREQEEKRRLEELER 443 Query: 81 GLDEDETNFLDE-----VSRQQELIEKQRREEELKELKEYRNNL--KKVGISQENKKEVE 133 E+E E V R+QE I +Q EEE + L+ + L ++ + + +E+E Sbjct: 444 RRKEEEERRRAEEEKRRVEREQEYIRRQ-LEEEQRHLEVLQQQLLQEQAMLLECRWREME 502 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQEPS 185 + + ++ + + QA LL+ H+ +S + P P + +PS Sbjct: 503 EHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHS----QQPPPPQQERSKPS 550 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 46.2 bits (108), Expect = 3e-05 Identities = 43/176 (24%), Positives = 85/176 (48%), Gaps = 13/176 (7%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDP---EECPEEVYDPRSLYERLQEQKDRKQQE 68 K+ +S E +ER + + E E+VR+ E+ EE EE + E+ +++K++K++E Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298 Query: 69 YEEQFK-FKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQE 127 +E+ + F+ + E+ET + +S ++E E EEE+ KE K+ + ++ Sbjct: 2299 VQEKEEVFEEKEEIMSEEET---ESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355 Query: 128 NKKEVEKKLTVKPI-----ETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPD 178 +K + + V I K + + +L +K K + +K P P P+ Sbjct: 2356 RRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLK-KLMSTALEMKEKTPVPVPE 2410 Score = 40.0 bits (92), Expect = 0.002 Identities = 31/135 (22%), Positives = 69/135 (51%), Gaps = 7/135 (5%) Query: 11 IKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 +K+R+ E K +++ +V + E E EE+ SL + L++Q+ +E E Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEM---ESLLDELEKQESLSSEEEE 2249 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKK 130 E+ + + +E+E +E +++E E+++ E+E +E K+ + KK + ++ + Sbjct: 2250 EREEEEER----EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305 Query: 131 EVEKKLTVKPIETKN 145 EK+ + ET++ Sbjct: 2306 FEEKEEIMSEEETES 2320 Score = 38.5 bits (88), Expect = 0.006 Identities = 35/121 (28%), Positives = 62/121 (51%), Gaps = 14/121 (11%) Query: 26 KRRQEEWEK-VRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGL-- 82 K +EEWEK + + E+ E P E LQE K K +E+++ ++ NM+ Sbjct: 1479 KAWKEEWEKRLLQEEEKLHQAGEKLSPEE--EMLQEDKKLKWEEWKQVWE--NMLSSKSK 1534 Query: 83 -----DEDETNFLDEVSRQQELIEKQRREEE--LKELKEYRNNLKKVGISQENKKEVEKK 135 DE+E +EVSR+ E E+Q EE+ ++E ++ +K +++ + + E+K Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK 1594 Query: 136 L 136 L Sbjct: 1595 L 1595 Score = 37.4 bits (85), Expect = 0.013 Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Query: 16 VSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKF 75 + E E+ KRR + ++ ++ + P+E D E E+ + E E+Q Sbjct: 2184 IEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 + E+E +E R++E K+ E E K++++ KK ++ K+EV++K Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK-KEKKKEEVQEK 2302 Score = 35.8 bits (81), Expect = 0.037 Identities = 41/191 (21%), Positives = 83/191 (43%), Gaps = 26/191 (13%) Query: 13 KRFVSEAE--LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 +R +++ E +E K ++ E + E+ EE P L R +++K+ K+ + Sbjct: 2151 RRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIP-FLKRRWRKRKEAKRGDKP 2209 Query: 71 EQFKFKNMVRGLDEDE------TNFLDEVSRQQELI--------EKQRREEELKELKEYR 116 ++ KF + V ++ +E + LDE+ +Q+ L E++ REEE +E Sbjct: 2210 KE-KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268 Query: 117 NNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPE 176 ++ G ++ +KE E+K K + K + + K + E + + Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE--------KEEVFEEKEEIMSEEETES 2320 Query: 177 PDDKNQEPSSC 187 D+ +E SC Sbjct: 2321 LSDEEEEEESC 2331 Score = 35.0 bits (79), Expect = 0.063 Identities = 36/145 (24%), Positives = 82/145 (56%), Gaps = 11/145 (7%) Query: 13 KRFVSEAE-LDERRKRRQEEWEKV-RKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE 70 ++ EAE L ++RK+ ++WEKV R+ E + ++ + +++ + E+ +++Q + Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708 Query: 71 EQFKFKNMVRGLDEDETNFLDEVSRQQELI--EKQRREEELKELKEYRNNL--KKVGISQ 126 ++ K + + L+E E + ++E+S ++E + E+ + EE K+L E L ++ +S+ Sbjct: 1709 --WQEKELAQELEELEWD-MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765 Query: 127 ENKKEVEKKLTVKPIETKNKFSQAK 151 E K +++ + I+ K K +Q K Sbjct: 1766 EETKLAQEEELL--IQEKEKLAQHK 1788 >gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sapiens] Length = 1268 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/114 (25%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFKNMVRG 81 E+++R EE ++ E + E+ R L E+ + +K+ RKQQE E++ ++ +R Sbjct: 374 EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRR 433 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +E ++ ++++L E+++ E ++LK+ R+ L + ++ ++ VEKK Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487 Score = 31.6 bits (70), Expect = 0.70 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 56 ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY 115 E L+ Q+ +QQ E+ K R L + ++E Q+ +E+Q+R E KEL++ Sbjct: 366 EALRRQQLEQQQRENEEHK-----RQLLAERQKRIEEQKEQRRRLEEQQRRE--KELRKQ 418 Query: 116 RNNLKKVGISQENKKEVEKKLTVKPIETKNK 146 + ++ ++ ++E E++ E K K Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYKRK 449 >gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sapiens] Length = 1276 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/114 (25%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFKNMVRG 81 E+++R EE ++ E + E+ R L E+ + +K+ RKQQE E++ ++ +R Sbjct: 374 EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRR 433 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +E ++ ++++L E+++ E ++LK+ R+ L + ++ ++ VEKK Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487 Score = 31.6 bits (70), Expect = 0.70 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 56 ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY 115 E L+ Q+ +QQ E+ K R L + ++E Q+ +E+Q+R E KEL++ Sbjct: 366 EALRRQQLEQQQRENEEHK-----RQLLAERQKRIEEQKEQRRRLEEQQRRE--KELRKQ 418 Query: 116 RNNLKKVGISQENKKEVEKKLTVKPIETKNK 146 + ++ ++ ++E E++ E K K Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYKRK 449 >gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sapiens] Length = 1323 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/114 (25%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFKNMVRG 81 E+++R EE ++ E + E+ R L E+ + +K+ RKQQE E++ ++ +R Sbjct: 374 EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRR 433 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +E ++ ++++L E+++ E ++LK+ R+ L + ++ ++ VEKK Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487 Score = 31.6 bits (70), Expect = 0.70 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 56 ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY 115 E L+ Q+ +QQ E+ K R L + ++E Q+ +E+Q+R E KEL++ Sbjct: 366 EALRRQQLEQQQRENEEHK-----RQLLAERQKRIEEQKEQRRRLEEQQRRE--KELRKQ 418 Query: 116 RNNLKKVGISQENKKEVEKKLTVKPIETKNK 146 + ++ ++ ++E E++ E K K Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYKRK 449 >gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sapiens] Length = 1331 Score = 46.2 bits (108), Expect = 3e-05 Identities = 29/114 (25%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKD-RKQQEYEEQFKFKNMVRG 81 E+++R EE ++ E + E+ R L E+ + +K+ RKQQE E++ ++ +R Sbjct: 374 EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRR 433 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +E ++ ++++L E+++ E ++LK+ R+ L + ++ ++ VEKK Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487 Score = 31.6 bits (70), Expect = 0.70 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 56 ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY 115 E L+ Q+ +QQ E+ K R L + ++E Q+ +E+Q+R E KEL++ Sbjct: 366 EALRRQQLEQQQRENEEHK-----RQLLAERQKRIEEQKEQRRRLEEQQRRE--KELRKQ 418 Query: 116 RNNLKKVGISQENKKEVEKKLTVKPIETKNK 146 + ++ ++ ++E E++ E K K Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYKRK 449 >gi|117553580 adaptor-related protein complex 3, delta 1 subunit isoform 2 [Homo sapiens] Length = 1153 Score = 45.8 bits (107), Expect = 4e-05 Identities = 48/200 (24%), Positives = 85/200 (42%), Gaps = 26/200 (13%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPED--PEECPEEVYDPRSLYERLQEQKDRKQQEY 69 ++R + E D+RRK+R+E+ +K ++ P E E++ + + +E + Sbjct: 730 ERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSD 789 Query: 70 EEQFKFKNMVRGLDEDETNFL-------------DEVSRQQE----LIEKQRREEELKEL 112 E+ + R LD D L E S+ E ++EK+ ++ + KE Sbjct: 790 EDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEK 849 Query: 113 KEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLK 172 K K E KKE EKK + KP + K++ + + G K K G+ + Sbjct: 850 KHKEKERDK-----EKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGE 904 Query: 173 P--DPEPDDKNQEPSSCKSL 190 P + P+++ P S SL Sbjct: 905 PVQNGAPEEEQLPPESSYSL 924 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 45.8 bits (107), Expect = 4e-05 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 23/176 (13%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 +A ER +R EE E++R+ E R+ ER Q K+ +++ EE+ + K Sbjct: 300 KAAAQERERREAEERERMREEEK-----------RAAEER-QRIKEEEKRAAEERQRIKE 347 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEE----LKELKEYRNNLKKVGISQENK---K 130 + E+ +E R E ++ R EEE ++E K + +K QE K + Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407 Query: 131 EVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSV--KRLK-PDPEPDDKNQE 183 +VE+K+ K + K K + KL +K + E G V KR K + +P K +E Sbjct: 408 KVEQKIEGKWVNEK-KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE 462 Score = 33.9 bits (76), Expect = 0.14 Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 27/173 (15%) Query: 12 KKRFVSEAE-LDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYE---RLQEQKDRKQQ 67 +KR E + + E KR EE ++++ E+ + EE R+ E +++EQK KQ Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIK--EEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392 Query: 68 EYEEQFKFKNMVRGLDED---ETNFLDEVSRQQE-----LIEKQRREEELK------ELK 113 E ++ + ++G + E +++E Q++ +++KQ E+ K +L+ Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452 Query: 114 EYRNNLKKVGISQEN-------KKEVEKKLTVKPIETKNKFSQAKLLAGAVKH 159 E + KK I E K+EV+ + K T+ K + + +KH Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH 505 Score = 32.7 bits (73), Expect = 0.31 Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 8/130 (6%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMV 79 +L+E++ QE K K E E + V + ++ ++LQ +KQ E E+ K + Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIE-GKWVNEKKAQEDKLQTAVLKKQGE-EKGTKVQAKR 448 Query: 80 RGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVK 139 L ED+ F E + +++ + + +EE+K + + +V K + + +T K Sbjct: 449 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV------KSQNGEFMTHK 502 Query: 140 PIETKNKFSQ 149 T+N FS+ Sbjct: 503 LKHTENTFSR 512 Score = 30.4 bits (67), Expect = 1.6 Identities = 36/177 (20%), Positives = 64/177 (36%), Gaps = 36/177 (20%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVY------------------------DPRS 53 EA + RR+ RQE + ++ E + ++V D + Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAA 95 Query: 54 LYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELK 113 ERL +++R+Q+ +E + + D + L Q + E + E+E K Sbjct: 96 FLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEK--- 152 Query: 114 EYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKR 170 S++ + E+E+ TV KN + A+ K K E KR Sbjct: 153 ---------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200 Score = 29.6 bits (65), Expect = 2.7 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 7/115 (6%) Query: 25 RKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDE 84 R + + E K E+ EE P+ + E + E+K + QE KN +E Sbjct: 178 RDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEE 237 Query: 85 DETNFLDEVSRQQ---ELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + E R+Q E+ ++ EEE KE E + + K E +KK+ Sbjct: 238 PK----QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288 Score = 29.3 bits (64), Expect = 3.5 Identities = 41/204 (20%), Positives = 83/204 (40%), Gaps = 52/204 (25%) Query: 26 KRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQK----------------------- 62 K+ + + EK++K ++P+E + D + + ++ Q Sbjct: 459 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS 518 Query: 63 -DRKQQEYEEQF----KFKNMVRGLDEDETNFLDEVSRQQ-----ELIE-KQRREEELKE 111 D K+ E Q + + + R E E+ +++ ++Q EL E K++REE K Sbjct: 519 VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 578 Query: 112 LKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRL 171 L+E K+ ++ ++E EK+ + IE + +E+ +++ Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRRLKEEIE----------------RRRAEAAEKRQKM 622 Query: 172 KPDPEPDDKNQEPSSCKSLGNTSL 195 D DDK +P C + +SL Sbjct: 623 PEDGLSDDK--KPFKCFTPKGSSL 644 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 44.7 bits (104), Expect = 8e-05 Identities = 35/127 (27%), Positives = 65/127 (51%), Gaps = 8/127 (6%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--YEEQFKF 75 E ++ E+ ++ E+ EK+R+ E+ EE + R QEQK R Q+E +E+ + Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406 Query: 76 KNMVRGLDEDETNF-----LDEVSRQQELIEKQR-REEELKELKEYRNNLKKVGISQENK 129 + + E E + + E + QE +K R +EE+++E + R KK+ +E Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 130 KEVEKKL 136 +E E+K+ Sbjct: 467 REQEEKM 473 Score = 43.1 bits (100), Expect = 2e-04 Identities = 38/170 (22%), Positives = 78/170 (45%), Gaps = 8/170 (4%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLY----ERLQEQKDRKQQEYEEQF 73 E + E+ K+ ++ EK+R+ E E +++ + + E++QEQ+++ Q++ E+ + Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627 Query: 74 KFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVE 133 + + + E E ++ + E EK ++ L E KE +K+ QE +E E Sbjct: 628 EQEEK---MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ-EQEKMQEQE 683 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDKNQE 183 +K+ + K Q K K + ES ++ + E + QE Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733 Score = 42.7 bits (99), Expect = 3e-04 Identities = 29/121 (23%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--YEEQFKF 75 E EL E+ K +E+ E + E +E E++++ R QE+K +Q+E +E++ + Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM-REQEEKMWRQEERLWEQEKQM 385 Query: 76 KNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 + + + + E ++ R +E E+ R +E++ E E KK+ ++ ++ E+K Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Query: 136 L 136 + Sbjct: 446 M 446 Score = 42.0 bits (97), Expect = 5e-04 Identities = 26/125 (20%), Positives = 64/125 (51%), Gaps = 2/125 (1%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R + E +++ QE+ EK+ + E+ EE++ R ++ ++++ Q +E+ Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + K ++ + + + E + Q++ Q EE+++E + R KK+ +E +E Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ--EEKMREEERMREREKKMREEEEMMRE 607 Query: 132 VEKKL 136 E+K+ Sbjct: 608 QEEKM 612 Score = 41.6 bits (96), Expect = 7e-04 Identities = 28/115 (24%), Positives = 61/115 (53%), Gaps = 3/115 (2%) Query: 25 RKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRK--QQEYEEQFKFKNMVRGL 82 +K + E EK+++ E +E E++++ + ++ QEQ+ + Q++ E+ + + + Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722 Query: 83 DEDETNFLDEVSRQQELIEK-QRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 E+E ++ + QE EK Q +EEE+ E +E ++ Q+ E ++KL Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777 Score = 40.4 bits (93), Expect = 0.002 Identities = 34/127 (26%), Positives = 67/127 (52%), Gaps = 12/127 (9%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDR--KQQEY 69 +K + E L E+ K+ +E+ +K+R E E +++ ERL+E+++R +Q++ Sbjct: 369 EKMWRQEERLWEQEKQMREQEQKMRDQE------ERMWEQD---ERLREKEERMREQEKM 419 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGISQEN 128 EQ + + + E E D+ + QE + RE++++E +E R +K+ +EN Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479 Query: 129 KKEVEKK 135 E E+K Sbjct: 480 MWEQEEK 486 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/121 (26%), Positives = 67/121 (55%), Gaps = 5/121 (4%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE-YEEQFKFK 76 E + E+ +R +E+ E++R+ E E E++ + + + E QE+K R Q+E +E+ + + Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE--QEKKTRDQEEKMQEEERIR 453 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGI-SQENKKEVEKK 135 + + E+E ++ + Q+ E+ E+E KE ++ R +K + QE +E E+K Sbjct: 454 EREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512 Query: 136 L 136 + Sbjct: 513 I 513 Score = 40.4 bits (93), Expect = 0.002 Identities = 26/115 (22%), Positives = 59/115 (51%), Gaps = 11/115 (9%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRG 81 ++ R++ + WE+ K D E+ +++D E+ +++++K + EE+ + + +R Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQ---KMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR- 592 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 E E +E +E EK + +EE + +E +K+ +E +E E+K+ Sbjct: 593 --EREKKMREEEEMMREQEEKMQEQEEKMQEQE-----EKMWEQEEKMQEQEEKM 640 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/150 (21%), Positives = 72/150 (48%), Gaps = 9/150 (6%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYE----RLQEQKDRKQQEY--EEQF 73 E ++ +++ ++ WE+ + + +E ++ +D + E R +E+K R+++E E++ Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734 Query: 74 KFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVE 133 K + + E E ++ + E EK ++ L E KE +K+ QE +K E Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM---QEQEKIWE 791 Query: 134 KKLTVKPIETKNKFSQAKLLAGAVKHKSSE 163 ++ ++ E K + + K+ K + E Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821 Score = 39.3 bits (90), Expect = 0.003 Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + EL E+ ++ QE+ EK+ + E+ EE + ERL EQ+ KQ +E Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQE--KQMREQE 389 Query: 72 QFKFKNMVRGLDEDE-----TNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQ 126 Q R ++DE + E + E +EK R E++++E ++ + ++ + Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449 Query: 127 ENKKEVEKKL 136 E +E EKK+ Sbjct: 450 ERIREREKKM 459 Score = 39.3 bits (90), Expect = 0.003 Identities = 29/140 (20%), Positives = 68/140 (48%), Gaps = 24/140 (17%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQ---KDRKQQEYEEQFKFK 76 E +ER + +++ WE+V K + ++ E+ R E++QE+ ++R+++ EE+ + Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467 Query: 77 NMVRGLDEDETNFLDEVSRQ---------------QELIEKQR-----REEELKELKEYR 116 + + E N ++ ++ QE +++Q +EE++++ +E Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 527 Query: 117 NNLKKVGISQENKKEVEKKL 136 KK+ QE +E E ++ Sbjct: 528 GQEKKMW-RQEKMREQEDQM 546 Score = 37.4 bits (85), Expect = 0.013 Identities = 32/134 (23%), Positives = 69/134 (51%), Gaps = 21/134 (15%) Query: 8 NLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQ 67 N + ++ + E EL E+ K+ +++ EK+ + E ERL+EQ+ + ++ Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQE----------------ERLREQEGKMRE 311 Query: 68 EYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK----QRREEELKELKE-YRNNLKKV 122 + E+ ++ + +R +++ E+ Q+EL E+ Q +EE++ E +E R +K+ Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371 Query: 123 GISQENKKEVEKKL 136 +E E EK++ Sbjct: 372 WRQEERLWEQEKQM 385 Score = 36.2 bits (82), Expect = 0.028 Identities = 34/146 (23%), Positives = 73/146 (50%), Gaps = 12/146 (8%) Query: 12 KKRFVSEAELDERRKRRQEEWEKV-----RKPEDPEECPEEVYDPRSLYERLQEQKDRKQ 66 +K + E L E+ + +E+ EK+ R E +E E+ + R E L+EQ+++ Q Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQ 351 Query: 67 QEYEEQFKFKNMVRGLDE----DETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKV 122 ++ E+ ++ + +R +E E ++ + +E +K R +EE ++ R K+ Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411 Query: 123 GISQENK--KEVEKKLTVKPIETKNK 146 + ++ K ++VEK K ++ + K Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEK 437 Score = 33.5 bits (75), Expect = 0.18 Identities = 29/120 (24%), Positives = 65/120 (54%), Gaps = 9/120 (7%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E+ + +K R+EE E +R+ E+ + EE + E+ +E +++++ +E++ K Sbjct: 713 ESMREREKKMREEE-EMMREQEEKMQEQEE-----KMQEQEEEMWEQEEKMWEQEEKMWE 766 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKE-YRNNLKKVGISQENKKEVEKKL 136 R ++ E + E ++QE I +Q EE++++ +E R +K+ +E + E+K+ Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQ--EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 44.7 bits (104), Expect = 8e-05 Identities = 34/126 (26%), Positives = 62/126 (49%), Gaps = 2/126 (1%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--Y 69 KK E ++ E+ ++ E+ EK+R+ E+ EE + R QEQK R Q+E + Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENK 129 E+ + + + E E + E Q+E ++R ++ +E + R +K+ +EN Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422 Query: 130 KEVEKK 135 E E+K Sbjct: 423 WEQEEK 428 Score = 43.5 bits (101), Expect = 2e-04 Identities = 28/120 (23%), Positives = 63/120 (52%), Gaps = 1/120 (0%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQK-DRKQQEYEEQFKFK 76 E EL E++K R++E + + E E E++ + R +E+ ++++Q E++ K + Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + + E + ++ R +E + +EE+++E + R KK+ +E +E E+K+ Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415 Score = 43.1 bits (100), Expect = 2e-04 Identities = 27/130 (20%), Positives = 66/130 (50%), Gaps = 7/130 (5%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 ++R + E +++ QE+ EK+ + E+ EE++ R ++ ++++ Q +E+ Sbjct: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQR-------REEELKELKEYRNNLKKVGI 124 + K ++ + + + E ++ R +E E+ R +EE+++E K+ + KK Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551 Query: 125 SQENKKEVEK 134 +E +E E+ Sbjct: 552 QEEKMREEER 561 Score = 42.7 bits (99), Expect = 3e-04 Identities = 39/163 (23%), Positives = 78/163 (47%), Gaps = 13/163 (7%) Query: 22 DERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRG 81 ++ R++ + WE+ K D E+ +++D ER+ EQ +R +++ E + K M Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQ---KMWDQE---ERMWEQDERLREKEERMREQKKMW-- 530 Query: 82 LDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPI 141 + E +E Q++ + +EE+++E + R KK+ +E +E E+K+ + Sbjct: 531 --QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ-- 586 Query: 142 ETKNKFSQAKLLAGAVKHKSSESGNSVKRLKP-DPEPDDKNQE 183 E K + + K+ K + E + K + E +DK QE Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629 Score = 42.7 bits (99), Expect = 3e-04 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 8/125 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 KK E + E+ ++ QE+ EK+R+ E+ EE + E++ EQ++ K E EE Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE--EKMWEQEE-KMWEQEE 623 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + K + + E E ++ + E EK R +EE + R +K+ +E +E Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE-----KMREQEEKMQGQEEKMRE 678 Query: 132 VEKKL 136 E+K+ Sbjct: 679 QEEKM 683 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/120 (23%), Positives = 62/120 (51%), Gaps = 4/120 (3%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYE---EQFKFK 76 E +ER + +++ WE+ K ++ E E R E ++EQ+++ Q++ E EQ + + Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + L E + ++ Q++ + +EE++++ +E KK+ QE +E E ++ Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW-RQEKMREQEDQM 488 Score = 39.3 bits (90), Expect = 0.003 Identities = 29/118 (24%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E ++ E+ ++ E+ EK+ + E+ ++ E+ E++QEQ++ K E EE Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE-KMWEQEE 653 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENK 129 + + + E++ +E R+QE + Q +EE+++E +E ++ QE K Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQE-EKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710 Score = 38.1 bits (87), Expect = 0.007 Identities = 27/134 (20%), Positives = 68/134 (50%), Gaps = 9/134 (6%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPE--------DPEECPEEVYDPRSLYERLQEQKD 63 +K + E L E+ + +E+ EK+R+ E + E +E+ + + L E+ ++ ++ Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314 Query: 64 RKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVG 123 ++++ +E++ K + + E ++ + +E +K R +EE ++ R K+ Sbjct: 315 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374 Query: 124 ISQENKK-EVEKKL 136 + ++ K E E+K+ Sbjct: 375 MREQEKMWEQEEKM 388 Score = 38.1 bits (87), Expect = 0.007 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 11/134 (8%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQE--Y 69 +K + E L E+ K+ +E+ +K+R E E E+ R ER++EQ+ +QE Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQE--ERMWEQDERLREKEERMREQEKMWEQEEKM 388 Query: 70 EEQFKFKNMVRGLDEDETNFLDEVSRQQ-------ELIEKQRREEELKELKEYRNNLKKV 122 +E+ + + + + E+E ++ + Q E EK+ +++ L E KE +K+ Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448 Query: 123 GISQENKKEVEKKL 136 +E E E+K+ Sbjct: 449 QEQEEKIWEQEEKI 462 Score = 38.1 bits (87), Expect = 0.007 Identities = 29/147 (19%), Positives = 66/147 (44%), Gaps = 8/147 (5%) Query: 20 ELDERRKRRQEEW---EKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFK 76 E +ER + +++ W EK+R+ + +E ++ +D + ++R+++ EE+ + Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577 Query: 77 NMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 + E E ++ + E EK + +EE +E +K+ +E K E++ Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE-----EKMWEQEEEDKMQEQEE 632 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSE 163 + E K + + K+ K + E Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQE 659 Score = 37.4 bits (85), Expect = 0.013 Identities = 29/133 (21%), Positives = 69/133 (51%), Gaps = 6/133 (4%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 +K + E + E+ +R +E+ E++R+ + + E++ + + E+ ++ D++++ EE Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + + + + + E+E ++ + QE EK R +EE +E +K+ +E E Sbjct: 560 E-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE-----EKMQEQEEKMWE 613 Query: 132 VEKKLTVKPIETK 144 E+K+ + E K Sbjct: 614 QEEKMWEQEEEDK 626 Score = 37.4 bits (85), Expect = 0.013 Identities = 24/99 (24%), Positives = 55/99 (55%), Gaps = 2/99 (2%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E ++ E+ ++ +E+ EK+R+ E+ + EE R E++Q Q+++ +++ E+ + Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKM--REQEEKMQGQEEKMREQEEKMRGQEE 702 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYR 116 + G +E +++ Q+E+ EK+ R + KE + R Sbjct: 703 KMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741 Score = 35.8 bits (81), Expect = 0.037 Identities = 33/147 (22%), Positives = 67/147 (45%), Gaps = 8/147 (5%) Query: 22 DERRKRRQEEW--EKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMV 79 D+ K R+EE E+ +K + EE E + E +++ K E EE+ + + Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610 Query: 80 RGLDED---ETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKKL 136 E+ E D++ Q+E++ +Q + + +E K + +K+ +E +E E+K+ Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKM 669 Query: 137 TVKPIETKNKFSQAKLLAGAVKHKSSE 163 + E K + + K+ K + E Sbjct: 670 QGQ--EEKMREQEEKMQGQEEKMREQE 694 Score = 35.4 bits (80), Expect = 0.048 Identities = 29/129 (22%), Positives = 63/129 (48%), Gaps = 25/129 (19%) Query: 8 NLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQ 67 N + ++ + E EL E+ K+ +++ EK+ + E ERL+EQ+ + ++ Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQE----------------ERLREQEGKMRE 273 Query: 68 EYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQE 127 + E K + + L E E ++ +E + + +EE+++E +E K+ +E Sbjct: 274 QEE---KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE------KMWEQEE 324 Query: 128 NKKEVEKKL 136 +E E+K+ Sbjct: 325 KMREQEEKM 333 >gi|92859701 myosin VI [Homo sapiens] Length = 1285 Score = 44.7 bits (104), Expect = 8e-05 Identities = 27/92 (29%), Positives = 54/92 (58%), Gaps = 9/92 (9%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 + E+++ RKRR+E+ ++ RK E+ E+ +R QE+++RK++E +E K Sbjct: 930 QEEMEKERKRREEDEKRRRKEEEERRMKLEME-----AKRKQEEEERKKREDDE----KR 980 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEEL 109 + ++ +E S+QQ ++E++RR+ EL Sbjct: 981 IQAEVEAQLARQKEEESQQQAVLEQERRDREL 1012 Score = 36.2 bits (82), Expect = 0.028 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 56 ERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEY 115 E++Q++ D + EE + E+E L + + E K+R E+E + KE Sbjct: 893 EQIQKEYDALVKSSEELLSALQKKKQ-QEEEAERLRRIQEEMEKERKRREEDEKRRRKEE 951 Query: 116 RNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSES 164 K+ + + K+E E++ K E K QA++ A + K ES Sbjct: 952 EERRMKLEMEAKRKQEEEER---KKREDDEKRIQAEVEAQLARQKEEES 997 Score = 28.1 bits (61), Expect = 7.7 Identities = 21/103 (20%), Positives = 48/103 (46%), Gaps = 12/103 (11%) Query: 20 ELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMV 79 E++ +RK QEE E+ ++ +D + EV + R +E++ ++Q E++ + + + Sbjct: 959 EMEAKRK--QEEEERKKREDDEKRIQAEV---EAQLARQKEEESQQQAVLEQERRDRELA 1013 Query: 80 RGLDEDETNFLDE-------VSRQQELIEKQRREEELKELKEY 115 + + E + + + R K E+ KE+ E+ Sbjct: 1014 LRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEF 1056 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 44.3 bits (103), Expect = 1e-04 Identities = 26/104 (25%), Positives = 60/104 (57%), Gaps = 7/104 (6%) Query: 18 EAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKN 77 E + E+RK +++E EK +K ++ E+ E+ + + + +++K+ +++E EE+ + Sbjct: 26 EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE-- 83 Query: 78 MVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKK 121 +E E +E R+++ +++R+EEE ++ K+ R KK Sbjct: 84 -----EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 Score = 43.1 bits (100), Expect = 2e-04 Identities = 27/113 (23%), Positives = 63/113 (55%), Gaps = 7/113 (6%) Query: 23 ERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGL 82 +++K++++E E+ + E+ EE E+ + +E++ K++E E++ K K + Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKE-------GKRKEKRKEKRKEKEKKKKTKETEKRK 53 Query: 83 DEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKEVEKK 135 +++E + R+++ E++R EEE +E +E K+ G ++ KK+ +K Sbjct: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 Score = 39.7 bits (91), Expect = 0.003 Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 14/135 (10%) Query: 12 KKRFVSEAELDERRKRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQKDRKQQEYEE 71 KK+ E E E + +EE EK K ++ + + + + + +++K+++++E + Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 Query: 72 QFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLKKVGISQENKKE 131 + K K +E ++E E++ +EEE KE R KK + K+E Sbjct: 63 KRKRKKKKE----------EEEREEEEEEEEEEKEEEEKEEGRRRKKKKK----RRRKEE 108 Query: 132 VEKKLTVKPIETKNK 146 E+K + +TK K Sbjct: 109 EEEKKKKRRRKTKKK 123 Score = 28.5 bits (62), Expect = 5.9 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 61 QKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELKELKEYRNNLK 120 +K +K+++ E+ + +E E ++ +++ EK+++ +E ++ KE K Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 121 KVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPEPDDK 180 K ++ KKE E++ + E + K + K K K KR + + E + K Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK-------KRRRKEEEEEKK 113 Query: 181 NQEPSSCK 188 + K Sbjct: 114 KKRRRKTK 121 >gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] Length = 1317 Score = 44.3 bits (103), Expect = 1e-04 Identities = 49/161 (30%), Positives = 76/161 (47%), Gaps = 20/161 (12%) Query: 18 EAELDERRKRRQEEWEKVRKPE--DPEECPEEVYDPRSLYERLQEQKDRKQQEY--EEQF 73 E E E +++ EE E+ +K + + E +EV R E +Q Q RKQ+E F Sbjct: 605 ELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQI-RKQEESLKRRSF 663 Query: 74 KFKNMVRGLDEDETNFLDEVSRQQELIEKQRR----------EEELKELKEYRNNLK--K 121 +N ++ L ++ F +E R+Q+ IE Q++ +EEL+ LKE NN K K Sbjct: 664 HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEK 723 Query: 122 VGISQE---NKKEVEKKLTVKPIETKNKFSQAKLLAGAVKH 159 I QE +KE +++ +E K Q K V H Sbjct: 724 FQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764 Score = 37.7 bits (86), Expect = 0.010 Identities = 38/150 (25%), Positives = 78/150 (52%), Gaps = 23/150 (15%) Query: 8 NLIIKKRFVSEAELDERR-----KRRQEEWEKVRKPEDPEECPEEVYDPRSLYERLQEQK 62 +L+ +K E L E++ K+RQEE +R E+ + E + ++ ++ ++ Sbjct: 671 DLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQEL 730 Query: 63 DRKQQEYEEQF-KFKNMVRGLDEDE-------TNFLDEVSRQQELIEKQRR------EEE 108 D+ Q+E +EQ+ K + + L+E E + +++ +QE+I+ RR EEE Sbjct: 731 DQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEE 790 Query: 109 LKELKEYRNNLKKVGISQ----ENKKEVEK 134 ++L+ R +L +V ++ E+ +E+EK Sbjct: 791 KRDLEGIRESLLRVKEARAGGDEDGEELEK 820 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.127 0.348 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,736,794 Number of Sequences: 37866 Number of extensions: 575878 Number of successful extensions: 6698 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 222 Number of HSP's successfully gapped in prelim test: 668 Number of HSP's that attempted gapping in prelim test: 3451 Number of HSP's gapped (non-prelim): 2467 length of query: 254 length of database: 18,247,518 effective HSP length: 100 effective length of query: 154 effective length of database: 14,460,918 effective search space: 2226981372 effective search space used: 2226981372 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.