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Search of human proteins with 51173727
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens] 991 0.0
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens] 991 0.0
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens] 875 0.0
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens] 875 0.0
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens] 875 0.0
gi|187828357 SMAD family member 9 isoform a [Homo sapiens] 783 0.0
gi|5174519 SMAD family member 9 isoform b [Homo sapiens] 749 0.0
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [... 555 e-158
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi... 551 e-157
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 536 e-152
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 536 e-152
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3... 484 e-137
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2... 409 e-114
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4... 343 1e-94
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens] 265 7e-71
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens] 96 9e-20
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 95 2e-19
gi|5174517 SMAD family member 7 [Homo sapiens] 92 8e-19
gi|4557317 annexin A11 [Homo sapiens] 51 3e-06
gi|22165433 annexin A11 [Homo sapiens] 51 3e-06
gi|22165431 annexin A11 [Homo sapiens] 51 3e-06
gi|167555104 interferon regulatory factor 4 [Homo sapiens] 45 2e-04
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 44 2e-04
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 44 4e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 5e-04
gi|209862789 microtubule associated monoxygenase, calponin and L... 43 5e-04
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 42 0.001
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 42 0.001
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 42 0.001
gi|32699048 family with sequence similarity 70, member B [Homo s... 41 0.003
>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 991 bits (2561), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ 60
MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ
Sbjct: 1 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ 60
Query: 61 PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 120
PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV
Sbjct: 61 PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 120
Query: 121 CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN 180
CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN
Sbjct: 121 CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN 180
Query: 181 SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ
Sbjct: 181 SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
Query: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 991 bits (2561), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ 60
MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ
Sbjct: 1 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQ 60
Query: 61 PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 120
PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV
Sbjct: 61 PSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 120
Query: 121 CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN 180
CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN
Sbjct: 121 CINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPN 180
Query: 181 SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ
Sbjct: 181 SHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
Query: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 875 bits (2262), Expect = 0.0
Identities = 417/465 (89%), Positives = 432/465 (92%), Gaps = 3/465 (0%)
Query: 2 NVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQP 61
++ SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS PGQP
Sbjct: 3 SMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQP 62
Query: 62 SNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVC 121
S CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEVC
Sbjct: 63 SKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVC 122
Query: 122 INPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNS 181
INPYHYKRVESPVLPPVLVPRH+E+NPQHSLL QFRNL NEPHMP NATFPDSF QPN+
Sbjct: 123 INPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNN 182
Query: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQP 241
PFP SPNS YP SP +SSTYP+SP SS PGSPFQ+PADTPPPAY+PP+D M QD SQP
Sbjct: 183 TPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 240
Query: 242 MDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
MDT N M P + I+ DVQ VAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
Sbjct: 241 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNNK+RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
Sbjct: 301 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
N+HHGFHPTTVCKIPS CSLKIFNNQEFAQLLAQSVNHGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 420
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 875 bits (2262), Expect = 0.0
Identities = 417/465 (89%), Positives = 432/465 (92%), Gaps = 3/465 (0%)
Query: 2 NVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQP 61
++ SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS PGQP
Sbjct: 3 SMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQP 62
Query: 62 SNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVC 121
S CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEVC
Sbjct: 63 SKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVC 122
Query: 122 INPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNS 181
INPYHYKRVESPVLPPVLVPRH+E+NPQHSLL QFRNL NEPHMP NATFPDSF QPN+
Sbjct: 123 INPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNN 182
Query: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQP 241
PFP SPNS YP SP +SSTYP+SP SS PGSPFQ+PADTPPPAY+PP+D M QD SQP
Sbjct: 183 TPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 240
Query: 242 MDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
MDT N M P + I+ DVQ VAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
Sbjct: 241 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNNK+RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
Sbjct: 301 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
N+HHGFHPTTVCKIPS CSLKIFNNQEFAQLLAQSVNHGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 420
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 875 bits (2262), Expect = 0.0
Identities = 417/465 (89%), Positives = 432/465 (92%), Gaps = 3/465 (0%)
Query: 2 NVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQP 61
++ SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS PGQP
Sbjct: 3 SMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQP 62
Query: 62 SNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVC 121
S CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEVC
Sbjct: 63 SKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVC 122
Query: 122 INPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNS 181
INPYHYKRVESPVLPPVLVPRH+E+NPQHSLL QFRNL NEPHMP NATFPDSF QPN+
Sbjct: 123 INPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNN 182
Query: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQP 241
PFP SPNS YP SP +SSTYP+SP SS PGSPFQ+PADTPPPAY+PP+D M QD SQP
Sbjct: 183 TPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP 240
Query: 242 MDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
MDT N M P + I+ DVQ VAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
Sbjct: 241 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNNK+RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
Sbjct: 301 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
N+HHGFHPTTVCKIPS CSLKIFNNQEFAQLLAQSVNHGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW 420
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
Length = 467
Score = 783 bits (2021), Expect = 0.0
Identities = 379/465 (81%), Positives = 407/465 (87%), Gaps = 6/465 (1%)
Query: 3 VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62
++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 7 ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
Query: 63 NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122
CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 67 KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
Query: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181
NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+ +EP MP NAT+PDSFQQP
Sbjct: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
Query: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
P SP+ ++ SP ++S YPHSP S S+P SP+Q DTPP Y E TQ G Q
Sbjct: 187 SALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSG-Q 243
Query: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
P+D + S I GD + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFT
Sbjct: 244 PVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302
Query: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
DPSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNC
Sbjct: 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362
Query: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
NY HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGW
Sbjct: 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422
Query: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
Length = 430
Score = 749 bits (1933), Expect = 0.0
Identities = 364/464 (78%), Positives = 389/464 (83%), Gaps = 41/464 (8%)
Query: 3 VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62
++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 7 ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
Query: 63 NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122
CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 67 KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
Query: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181
NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+ +EP MP NAT+PDSFQQP
Sbjct: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
Query: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQP 241
P SP+ ++ SP ++S YPHSP GSP + PE P
Sbjct: 187 SALPPSPSHAFSQSPCTAS--YPHSP-----GSPSE------------PESPY------- 220
Query: 242 MDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD 301
D + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFTD
Sbjct: 221 --------------QHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTD 266
Query: 302 PSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCN 361
PSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNCN
Sbjct: 267 PSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCN 326
Query: 362 YHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWG 421
Y HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGWG
Sbjct: 327 YQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWG 386
Query: 422 AEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
AEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 387 AEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
Length = 425
Score = 555 bits (1431), Expect = e-158
Identities = 286/471 (60%), Positives = 333/471 (70%), Gaps = 54/471 (11%)
Query: 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct: 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
Query: 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct: 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
Query: 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
Query: 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG- 238
P S+ P +TPPP YL ED T D
Sbjct: 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
Query: 239 -SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294
+ MD N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
Query: 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct: 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
Query: 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414
VQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct: 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
Query: 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
Length = 437
Score = 551 bits (1421), Expect = e-157
Identities = 288/482 (59%), Positives = 336/482 (69%), Gaps = 64/482 (13%)
Query: 3 VTSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 49
++S+ FT P VKRLLGWK Q +EEKW EKAV +LVKKLKK G ++
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 50 ELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
ELEKA++ + CVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 60 ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
Query: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLN 169
E+ F K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E +L + L +P N
Sbjct: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
Query: 170 ATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLP 229
FP + P S+Y +P +TPPP Y+
Sbjct: 174 TNFPAGIE----------PQSNY-------------------------IP-ETPPPGYIS 197
Query: 230 PEDPMTQDG--SQPMDTNM---MAPPLPSEINRG-DVQAVAYEEPKHWCSIVYYELNNRV 283
ED T D +Q MDT ++P S +N D+Q V Y EP WCSI YYELN RV
Sbjct: 198 -EDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRV 256
Query: 284 GEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEV 343
GE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV
Sbjct: 257 GETFHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEV 315
Query: 344 YAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETV 403
+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE V
Sbjct: 316 FAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAV 375
Query: 404 YELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISS 463
Y+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SS
Sbjct: 376 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSS 435
Query: 464 VS 465
+S
Sbjct: 436 MS 437
>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 536 bits (1380), Expect = e-152
Identities = 288/512 (56%), Positives = 336/512 (65%), Gaps = 94/512 (18%)
Query: 3 VTSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 49
++S+ FT P VKRLLGWK Q +EEKW EKAV +LVKKLKK G ++
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 50 ELEKALSCPGQPSNCVTIP------------------------------RSLDGRLQVSH 79
ELEKA++ + CVTIP RSLDGRLQVSH
Sbjct: 60 ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119
Query: 80 RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVL 139
RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F K+ EVC+NPYHY+RVE+PVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179
Query: 140 VPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSS 199
VPRH+E +L + L +P N FP + P S+Y
Sbjct: 180 VPRHTE------ILTELPPLDDYTHSIPENTNFPAGIE----------PQSNY------- 216
Query: 200 SSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG--SQPMDTNM---MAPPLPSE 254
+P +TPPP Y+ ED T D +Q MDT ++P S
Sbjct: 217 ------------------IP-ETPPPGYIS-EDGETSDQQLNQSMDTGSPAELSPTTLSP 256
Query: 255 INRG-DVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGL 313
+N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGL
Sbjct: 257 VNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGL 315
Query: 314 LSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCK 373
LSNVNRN+T+E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCK
Sbjct: 316 LSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCK 375
Query: 374 IPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTP 433
IP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTP
Sbjct: 376 IPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTP 435
Query: 434 CWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
CWIE+HL+GPLQWLDKVLTQMGSP SS+S
Sbjct: 436 CWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 536 bits (1380), Expect = e-152
Identities = 288/512 (56%), Positives = 336/512 (65%), Gaps = 94/512 (18%)
Query: 3 VTSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 49
++S+ FT P VKRLLGWK Q +EEKW EKAV +LVKKLKK G ++
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 50 ELEKALSCPGQPSNCVTIP------------------------------RSLDGRLQVSH 79
ELEKA++ + CVTIP RSLDGRLQVSH
Sbjct: 60 ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119
Query: 80 RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVL 139
RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F K+ EVC+NPYHY+RVE+PVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179
Query: 140 VPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSS 199
VPRH+E +L + L +P N FP + P S+Y
Sbjct: 180 VPRHTE------ILTELPPLDDYTHSIPENTNFPAGIE----------PQSNY------- 216
Query: 200 SSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG--SQPMDTNM---MAPPLPSE 254
+P +TPPP Y+ ED T D +Q MDT ++P S
Sbjct: 217 ------------------IP-ETPPPGYIS-EDGETSDQQLNQSMDTGSPAELSPTTLSP 256
Query: 255 INRG-DVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGL 313
+N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGL
Sbjct: 257 VNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGL 315
Query: 314 LSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCK 373
LSNVNRN+T+E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCK
Sbjct: 316 LSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCK 375
Query: 374 IPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTP 433
IP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTP
Sbjct: 376 IPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTP 435
Query: 434 CWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
CWIE+HL+GPLQWLDKVLTQMGSP SS+S
Sbjct: 436 CWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
[Homo sapiens]
Length = 381
Score = 484 bits (1246), Expect = e-137
Identities = 248/402 (61%), Positives = 282/402 (70%), Gaps = 50/402 (12%)
Query: 69 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYK 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
Query: 129 RVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSP 188
RVE+PVLPPVLVPRH+E + A+F L +P N FP + P
Sbjct: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE----------P 128
Query: 189 NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG--SQPMDT-- 244
S+ P +TPPP YL ED T D + MD
Sbjct: 129 QSNIP---------------------------ETPPPGYLS-EDGETSDHQMNHSMDAGS 160
Query: 245 -NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPS 303
N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPS
Sbjct: 161 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 220
Query: 304 NNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYH 363
N++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN
Sbjct: 221 NSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR 279
Query: 364 HGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAE 423
+G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAE
Sbjct: 280 YGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAE 339
Query: 424 YHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
Y RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 340 YRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
[Homo sapiens]
Length = 320
Score = 409 bits (1052), Expect = e-114
Identities = 215/365 (58%), Positives = 247/365 (67%), Gaps = 50/365 (13%)
Query: 106 LECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPH 165
+E CEF F K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L
Sbjct: 1 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHS 54
Query: 166 MPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225
+P N FP + P S+ P +TPPP
Sbjct: 55 IPENTNFPAGIE----------PQSNIP---------------------------ETPPP 77
Query: 226 AYLPPEDPMTQDG--SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELN 280
YL ED T D + MD N+ P+ N D+Q V Y EP WCSI YYELN
Sbjct: 78 GYLS-EDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELN 136
Query: 281 NRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVG 340
RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+G
Sbjct: 137 QRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 195
Query: 341 GEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGF 400
GEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GF
Sbjct: 196 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 255
Query: 401 ETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNP 460
E VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP
Sbjct: 256 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 315
Query: 461 ISSVS 465
SSVS
Sbjct: 316 CSSVS 320
>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
[Homo sapiens]
Length = 230
Score = 343 bits (881), Expect = 1e-94
Identities = 164/221 (74%), Positives = 183/221 (82%), Gaps = 1/221 (0%)
Query: 245 NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSN 304
N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN
Sbjct: 11 NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 70
Query: 305 NKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHH 364
++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +
Sbjct: 71 SE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 129
Query: 365 GFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEY 424
G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY
Sbjct: 130 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 189
Query: 425 HRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 190 RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
Length = 552
Score = 265 bits (677), Expect = 7e-71
Identities = 190/530 (35%), Positives = 265/530 (50%), Gaps = 95/530 (17%)
Query: 14 VKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG-QPSNCVTIPRSLD 72
V L+ +QG E E +A++A+++LVKKLK+KK ++ L A++ G PS CVTI R+LD
Sbjct: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
Query: 73 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVES 132
GRLQV+ RKG PHVIY R+WRWPDL +ELK ++ C++ F K VC+NPYHY+RV S
Sbjct: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
Query: 133 PVL-----------PPVLVPRHS---EYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQ 178
P + P ++ + ++ Q SL + ++ Q H P N +++
Sbjct: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSI-QTIQHPPSNRASTETYST 197
Query: 179 P-----------NSHPFPHSP--NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPP 225
P ++ FP+ P ++S P S S + +S P Q T P
Sbjct: 198 PALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQP 257
Query: 226 AYLPPEDPMTQDGSQ--PMDTNM---------MAPPLPSEINRGDVQAVAYE-------- 266
A T GS+ P N+ PP+P + G V E
Sbjct: 258 ATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPP--HPGHYWPVHNELAFQPPIS 315
Query: 267 ---EPKHWCSIVYYELNNRVGEAFHASSTS--VLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
P++WCSI Y+E++ +VGE F S+ V VDG+ DPS +RFCLG LSNV+R
Sbjct: 316 NHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSNVHRTE 374
Query: 322 TIENTRRHIGKGVHLYYVG-GEVYAECLSDSSIFVQSRNCNYHHGFHP-TTVCKIPSGCS 379
IE R HIGKGV L G G+V+ CLSD ++FVQS + G P V KI
Sbjct: 375 AIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAY 434
Query: 380 LKIFNNQE-----------------------------------FAQLLAQSVNHGFETVY 404
+K+F+ ++ A ++ S G V
Sbjct: 435 IKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGI-GVD 493
Query: 405 ELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 454
+L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
Length = 235
Score = 95.5 bits (236), Expect = 9e-20
Identities = 75/239 (31%), Positives = 108/239 (45%), Gaps = 17/239 (7%)
Query: 213 GSPFQMPADTPPP-AYLPPED---PMTQDGSQPMDTNMMAP----PLPSEINRGDVQAVA 264
G P + PPP + L P D P+ S T A P E + + A
Sbjct: 5 GKPIETQKSPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDA 64
Query: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIE 324
+P HWCS+ Y+E RVG + +V + F D FCLG L+ R+ ++
Sbjct: 65 -TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVR 120
Query: 325 NTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFN 384
TR IG G+ L V+A + IFV S + G V K+P G S+K+F+
Sbjct: 121 RTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFD 179
Query: 385 NQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 443
+ A + + Y+ ++R+SF KGWG Y RQ +TS PCW+EI L+ P
Sbjct: 180 FERSGLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 94.7 bits (234), Expect = 2e-19
Identities = 74/232 (31%), Positives = 107/232 (46%), Gaps = 18/232 (7%)
Query: 221 DTPPPAY--LPPED---PMTQDGSQPMDTNMMAP----PLPSEINRGDVQAVAYEEPKHW 271
++PPP Y L P D P+ S T A P E + + A +P HW
Sbjct: 273 ESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDA-TKPSHW 331
Query: 272 CSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIG 331
CS+ Y+E RVG + +V + F D FCLG L+ R+ ++ TR IG
Sbjct: 332 CSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIG 388
Query: 332 KGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQL 391
G+ L V+A + IFV S + G V K+P G S+K+F+ +
Sbjct: 389 FGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFERSGLQ 447
Query: 392 LAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 443
A + + Y+ ++R+SF KGWG Y RQ +TS PCW+EI L+ P
Sbjct: 448 HAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
Score = 67.0 bits (162), Expect = 3e-11
Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 10/116 (8%)
Query: 36 ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 94
+L+K+LK++ +++ L +A+ S G P CV +PR+ L++ + P ++ R++RW
Sbjct: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
Query: 95 PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQ 149
PDLQ ELKPL C F + VC NPYH+ R+ P PP P +S +P+
Sbjct: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPR 285
>gi|5174517 SMAD family member 7 [Homo sapiens]
Length = 426
Score = 92.4 bits (228), Expect = 8e-19
Identities = 111/417 (26%), Positives = 171/417 (41%), Gaps = 107/417 (25%)
Query: 36 ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRL-----------QVSHRKGL 83
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
Query: 84 PHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE-VCINPYHYKRVESPVLPPVLVPR 142
P ++ C+V+RWPDL+ E+K L CC +G E VC
Sbjct: 156 P-LLLCKVFRWPDLRHSSEVKRL-CCCESYGKINPELVCC-------------------- 193
Query: 143 HSEYNPQH-SLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSS 201
NP H S L + + P P S YP ++
Sbjct: 194 ----NPHHLSRLCELES--------------------------PPPPYSRYPMDFLKPTA 223
Query: 202 TYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQ 261
P + SS A+T YL P D+ ++ P GD
Sbjct: 224 DCPDAVPSS---------AETGGTNYLAP--------GGLSDSQLLLEP-------GD-- 257
Query: 262 AVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
HWC + Y+E RVG + S+ D F D N FCLG L++ N++
Sbjct: 258 ------RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQG-NGFCLGQLNSDNKSQ 308
Query: 322 TIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLK 381
++ R IG G+ L V+ S IF++S + + V K+ G S+K
Sbjct: 309 LVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIK 367
Query: 382 IFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
F+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 368 AFDYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/103 (33%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 154 AQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYP---NSPGSSSSTYPHSPTSS 210
A NL P P F QP S P P YP +P S +YP P +
Sbjct: 68 ANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAP 127
Query: 211 DPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPS 253
PG P P PP AY P + P+T G P+ P+PS
Sbjct: 128 VPGQPMPPPGQQPPGAY-PGQPPVTYPGQPPVPLPGQQQPVPS 169
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/103 (33%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 154 AQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYP---NSPGSSSSTYPHSPTSS 210
A NL P P F QP S P P YP +P S +YP P +
Sbjct: 68 ANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAP 127
Query: 211 DPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPS 253
PG P P PP AY P + P+T G P+ P+PS
Sbjct: 128 VPGQPMPPPGQQPPGAY-PGQPPVTYPGQPPVPLPGQQQPVPS 169
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/103 (33%), Positives = 41/103 (39%), Gaps = 4/103 (3%)
Query: 154 AQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYP---NSPGSSSSTYPHSPTSS 210
A NL P P F QP S P P YP +P S +YP P +
Sbjct: 68 ANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAP 127
Query: 211 DPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPS 253
PG P P PP AY P + P+T G P+ P+PS
Sbjct: 128 VPGQPMPPPGQQPPGAY-PGQPPVTYPGQPPVPLPGQQQPVPS 169
>gi|167555104 interferon regulatory factor 4 [Homo sapiens]
Length = 451
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/246 (21%), Positives = 94/246 (38%), Gaps = 38/246 (15%)
Query: 177 QQPNSHPFPHSPNSSYPNSPGSSSSTY----------PHSPTSSDPGSPFQMPADTPPPA 226
Q SHP+ + + YP+ P Y + P P P+Q P P
Sbjct: 145 QMSMSHPY--TMTTPYPSLPAQQVHNYMMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRG 202
Query: 227 YLPPEDPMTQDGSQPMDT-------NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYEL 279
+ + P ++G Q T AP +P+E + +A+A+ + + + Y E+
Sbjct: 203 H-HWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIRSAEALAFSDCRLHICLYYREI 261
Query: 280 NNRVGEAFHASSTSVLVD-GFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYY 338
V E +S + G T ++N ++ + + IE H+ +GV L+
Sbjct: 262 --LVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQRKNIEKLLSHLERGVVLWM 319
Query: 339 VGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVC-----KIPSGCSLKIFNNQEFAQLLA 393
+YA+ L S I+ P +C K+ + K+F+ Q+F L
Sbjct: 320 APDGLYAKRLCQSRIYWDG----------PLALCNDRPNKLERDQTCKLFDTQQFLSELQ 369
Query: 394 QSVNHG 399
+HG
Sbjct: 370 AFAHHG 375
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 10/128 (7%)
Query: 140 VPRHSEYNPQHSLLAQFRNL--GQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPG 197
VP P H +L Q + + G PL+AT + QQP + P S +PN
Sbjct: 1143 VPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAA 1202
Query: 198 SSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQD-------GSQPMDTNMMAPP 250
+ ++ P +P + P + + PP+ P E ++ + G P N+ PP
Sbjct: 1203 PTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPP 1262
Query: 251 LPSEINRG 258
P+ +NRG
Sbjct: 1263 RPN-LNRG 1269
Score = 29.6 bits (65), Expect = 6.1
Identities = 40/147 (27%), Positives = 51/147 (34%), Gaps = 35/147 (23%)
Query: 130 VESPVLPPVLVPRHSEYNPQ-HSLLAQFRNLGQ-NEPHMPLNATFPDSFQQPNSHPFPHS 187
V++P PP P S+ Q H+ Q N GQ P M P P P H
Sbjct: 366 VQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQP--HL 423
Query: 188 PNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMP---------ADTPP-----------PAY 227
N S P SS P+S GSP P PP P
Sbjct: 424 TNKS----PASS-------PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS 472
Query: 228 LPPEDPMTQDGSQPMDTNMMAPPLPSE 254
P +PM Q G+ P + +M P++
Sbjct: 473 SPGRNPMVQQGNVPPNFMVMQQQPPNQ 499
Score = 29.3 bits (64), Expect = 7.9
Identities = 38/143 (26%), Positives = 48/143 (33%), Gaps = 16/143 (11%)
Query: 129 RVESPVLPPVLVPRHSEYNP---QHSLLAQFRNLGQNE----PHMPLNATFPDSFQQPNS 181
RV +P+ P L + +P Q A + Q + P P N P FQQP S
Sbjct: 413 RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS 472
Query: 182 HPFPH---SPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG 238
P + + PN P S PG MP PP +P G
Sbjct: 473 SPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLG-GMPKRLPPGFSAGQANPNFMQG 531
Query: 239 SQPMDT-----NMMAPPLPSEIN 256
P T N AP L + N
Sbjct: 532 QVPSTTATTPGNSGAPQLQANQN 554
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 4/132 (3%)
Query: 125 YHYKRVESPVLPPVLVPRHSE--YNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSH 182
YH ES + + +H E + ++ RN ++ +P +A FPD S
Sbjct: 3529 YHCLACESALCGEEALSQHLESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQ 3588
Query: 183 PFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPM 242
HS +S P S + SS PH+ S P + A PP PP + S
Sbjct: 3589 SAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKPPS--FPPLSSSSTVTSSSC 3646
Query: 243 DTNMMAPPLPSE 254
T+ + P +P++
Sbjct: 3647 STSGVQPSMPTD 3658
Score = 34.3 bits (77), Expect = 0.25
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 39/120 (32%)
Query: 135 LPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMP--------LNATFPDSFQQPNSH-PFP 185
+PPVL+P G N P +P L + P+ P++ P P
Sbjct: 3121 IPPVLLP------------------GLNSPSLPGFTPSNTALTSPKPNLMGLPSTTVPSP 3162
Query: 186 HSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPAD------------TPPPAYLPPEDP 233
P S PN P S+S + P ++ P Q P PPPA PP P
Sbjct: 3163 GLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTP 3222
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 43.1 bits (100), Expect = 5e-04
Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 18/127 (14%)
Query: 132 SPVLPPVLVPRHSEYNPQ--HSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPN 189
SP L P+ P N H L A F P P+ A F P + P P SP+
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPF----SPPPSPPVQAPF-----SPPASP-PVSPS 688
Query: 190 SSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPP------EDPMTQDGSQPMD 243
++ P+ S + P S P SP P+ TPPP PP + P + S PM
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 244 TNMMAPP 250
+ PP
Sbjct: 749 PSATPPP 755
Score = 35.0 bits (79), Expect = 0.14
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 130 VESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHP---FPH 186
+++P PP P + ++P S P + +AT P + P P
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPAS------------PPVSPSATPPSQAPPSLAAPPLQVPP 708
Query: 187 SPNSSYPNSPGSSSSTYPHSPTS--------SDPGSPFQMPADTPPP------AYLPPED 232
SP +S P SP ++ P + S P SP P+ TPPP A P +
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
Query: 233 PMTQDGSQPMDTNMMAPP 250
P + S PM PP
Sbjct: 769 PPSPPASLPMSPLAKPPP 786
Score = 33.1 bits (74), Expect = 0.55
Identities = 32/132 (24%), Positives = 43/132 (32%), Gaps = 27/132 (20%)
Query: 133 PVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSY 192
P +PP+L + P L + P P P P +
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP--------------PLQAL 800
Query: 193 PNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYL---------PPEDPMTQDGSQP-- 241
P+ P S P SP++S P SP P PP PP P Q +P
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 242 --MDTNMMAPPL 251
DT++ P L
Sbjct: 861 PGPDTSVSGPRL 872
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 43.1 bits (100), Expect = 5e-04
Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 29/163 (17%)
Query: 95 PDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLA 154
P H E P + ++ + P H E P LPPV E +P+ L
Sbjct: 1141 PASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAAT-QEKSPEERLFP 1199
Query: 155 QFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGS 214
EP +P D+ P+ HSP S P T P + T PGS
Sbjct: 1200 --------EPLLPKEKPKADA---PSDLKAVHSPIRSQP-------VTLPEARTPVSPGS 1241
Query: 215 PFQMP---ADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSE 254
P P A TPPP+ LP SQP + P P++
Sbjct: 1242 PQPQPPVAASTPPPSPLP-------ICSQPQPSTEATVPSPTQ 1277
Score = 29.3 bits (64), Expect = 7.9
Identities = 36/143 (25%), Positives = 54/143 (37%), Gaps = 26/143 (18%)
Query: 132 SPVLPPVLVPRHS-EYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNS 190
+P PV + +S E +PQ L + L +P P +P S P P SP+
Sbjct: 1355 TPAFRPVSLKSYSVEKSPQDEGLHLLKPLS-----IPKRLGLPKPEGEPLSLPTPRSPSD 1409
Query: 191 SYPNSP-------GSSSSTYPHSPTSS----------DPGSPFQMPADTPPPAYLPPEDP 233
S SSS H +S+ S P +PPP P E+P
Sbjct: 1410 RELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEP 1469
Query: 234 MT---QDGSQPMDTNMMAPPLPS 253
T + + +++ PPLP+
Sbjct: 1470 ATLRRKLREAEPNASVVPPPLPA 1492
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 181 SHPFPHSPNSSYPNSPGSSSSTYPH---SPTSSDPGSPFQMPADTPPPAYL-PPEDPMTQ 236
S P+ H + P PG ++PH S T G P Q + PPP ++ PP PM Q
Sbjct: 376 SRPY-HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 237 D-------GSQPMDTNMMAPPLPSEINR 257
G PMD + + P+ S + R
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYR 462
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 181 SHPFPHSPNSSYPNSPGSSSSTYPH---SPTSSDPGSPFQMPADTPPPAYL-PPEDPMTQ 236
S P+ H + P PG ++PH S T G P Q + PPP ++ PP PM Q
Sbjct: 376 SRPY-HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 237 D-------GSQPMDTNMMAPPLPSEINR 257
G PMD + + P+ S + R
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYR 462
Score = 32.3 bits (72), Expect = 0.94
Identities = 31/127 (24%), Positives = 43/127 (33%), Gaps = 19/127 (14%)
Query: 136 PPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNS 195
PP P P L ++ Q P P P S +S P P N++ +
Sbjct: 480 PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP-----PPSSSMASSTPLPWQQNTTTTTT 534
Query: 196 PGSSSSTYP----HSPTSSDPGSP--------FQMPADTPPPAYLPPEDPMTQDGSQPMD 243
+ S P + ++ PG+P +P PP LPP P P
Sbjct: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP--LPPGAPPPPPPPPPGS 592
Query: 244 TNMMAPP 250
MM PP
Sbjct: 593 AGMMIPP 599
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
Query: 181 SHPFPHSPNSSYPNSPGSSSSTYPH---SPTSSDPGSPFQMPADTPPPAYL-PPEDPMTQ 236
S P+ H + P PG ++PH S T G P Q + PPP ++ PP PM Q
Sbjct: 376 SRPY-HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
Query: 237 D-------GSQPMDTNMMAPPLPSEINR 257
G PMD + + P+ S + R
Sbjct: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYR 462
Score = 30.4 bits (67), Expect = 3.6
Identities = 27/85 (31%), Positives = 29/85 (34%), Gaps = 15/85 (17%)
Query: 178 QPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDP---- 233
Q N P P P PG+ P P PGS M A PPP PP DP
Sbjct: 561 QGNPTMVPLPPGVQPPLPPGA-----PPPPPPPPPGSAGMMYAPPPPPP--PPMDPSNFV 613
Query: 234 ----MTQDGSQPMDTNMMAPPLPSE 254
M G P PP P +
Sbjct: 614 TMMGMGVAGMPPFGMPPAPPPPPPQ 638
>gi|32699048 family with sequence similarity 70, member B [Homo
sapiens]
Length = 326
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 19/100 (19%)
Query: 140 VPRHSEYNPQHSLLAQ--FRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSP- 196
VP + YNP +LA FR P+ +S+P P P S +P +P
Sbjct: 235 VPPQTLYNPAQQILAYAGFR-------------LTPEPVPTCSSYPLPLQPCSRFPVAPS 281
Query: 197 ---GSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDP 233
SS P SP+SS G P Q P P + P E P
Sbjct: 282 SALASSEDLQPPSPSSSGSGLPGQAPPCYAPTYFPPGEKP 321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,028,917
Number of Sequences: 37866
Number of extensions: 1205611
Number of successful extensions: 9740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 508
Number of HSP's that attempted gapping in prelim test: 7210
Number of HSP's gapped (non-prelim): 2363
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.