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Search of human proteins with 50428925
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50428925 cytoskeleton associated protein 1 [Homo sapiens]
(244 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50428925 cytoskeleton associated protein 1 [Homo sapiens] 490 e-139
gi|31982881 CAP-GLY domain containing linker protein family, mem... 77 2e-14
gi|38044112 restin isoform b [Homo sapiens] 74 1e-13
gi|4506751 restin isoform a [Homo sapiens] 74 1e-13
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 74 2e-13
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 74 2e-13
gi|46852172 kinesin family member 13B [Homo sapiens] 74 2e-13
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ... 70 2e-12
gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2... 70 2e-12
gi|18496983 CAP-GLY domain containing linker protein 3 [Homo sap... 70 2e-12
gi|171184451 centrosome-associated protein 350 [Homo sapiens] 56 3e-08
gi|118442828 beta-tubulin cofactor E [Homo sapiens] 46 3e-05
gi|4507375 beta-tubulin cofactor E [Homo sapiens] 46 3e-05
gi|109637774 ubiquitin carboxyl-terminal hydrolase CYLD isoform ... 36 0.035
gi|14165258 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1... 36 0.035
gi|109637776 ubiquitin carboxyl-terminal hydrolase CYLD isoform ... 36 0.035
gi|20357552 cortactin isoform a [Homo sapiens] 33 0.17
gi|20357556 cortactin isoform b [Homo sapiens] 33 0.23
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 33 0.23
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 30 1.5
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 30 1.5
gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 30 1.5
gi|6005757 chromatin-specific transcription elongation factor la... 30 1.9
gi|21735548 centrosomal protein 2 [Homo sapiens] 30 1.9
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 30 1.9
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 30 1.9
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 30 1.9
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 30 1.9
gi|209862782 hypothetical protein LOC730130 [Homo sapiens] 30 1.9
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 30 2.5
>gi|50428925 cytoskeleton associated protein 1 [Homo sapiens]
Length = 244
Score = 490 bits (1262), Expect = e-139
Identities = 244/244 (100%), Positives = 244/244 (100%)
Query: 1 MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVD 60
MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVD
Sbjct: 1 MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVD 60
Query: 61 DKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDT 120
DKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDT
Sbjct: 61 DKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDT 120
Query: 121 VRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVM 180
VRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVM
Sbjct: 121 VRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVM 180
Query: 181 YVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVTVGDFPEEDYG 240
YVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVTVGDFPEEDYG
Sbjct: 181 YVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVTVGDFPEEDYG 240
Query: 241 LDEI 244
LDEI
Sbjct: 241 LDEI 244
>gi|31982881 CAP-GLY domain containing linker protein family, member
4 [Homo sapiens]
Length = 705
Score = 76.6 bits (187), Expect = 2e-14
Identities = 41/116 (35%), Positives = 63/116 (54%), Gaps = 10/116 (8%)
Query: 122 RSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCE--------VRAAGQS 173
+S+ K+ N++ ++ + +++ A + A+S SRCE V GQ
Sbjct: 438 QSYPKKQNAISSNKKTMSKSPSLSSRASAGLNSSATSTANNSRCEGELRLGERVLVVGQ- 496
Query: 174 PRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVV 229
R GT+ + G T+F PGYW G+ ++P GKNDGSV G +YF C +YG F P+ V
Sbjct: 497 -RLGTIRFFGTTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCSPRYGIFAPPSRV 551
Score = 65.5 bits (158), Expect = 4e-11
Identities = 30/58 (51%), Positives = 36/58 (62%)
Query: 173 SPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVT 230
S GTV YVG TDF G W+G+ GKNDGSV KRYF C+ +G V+P+ VT
Sbjct: 634 SNEMGTVRYVGPTDFASGIWLGLELRSAKGKNDGSVGDKRYFTCKPNHGVLVRPSRVT 691
Score = 60.8 bits (146), Expect = 1e-09
Identities = 31/71 (43%), Positives = 42/71 (59%), Gaps = 2/71 (2%)
Query: 153 KAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKR 212
KA +S+ + V AGQ + GT+ + G T+F G W G+ DEP GKN+GSV +
Sbjct: 275 KAMLTSLGLKLGDRVVIAGQ--KVGTLRFCGTTEFASGQWAGIELDEPEGKNNGSVGKVQ 332
Query: 213 YFECQAKYGAF 223
YF+C KYG F
Sbjct: 333 YFKCAPKYGIF 343
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 73.9 bits (180), Expect = 1e-13
Identities = 40/86 (46%), Positives = 50/86 (58%), Gaps = 5/86 (5%)
Query: 154 AQASSIPVGSRCEVRAAGQ----SPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVN 209
++A SI G R E++ + + G V ++G TDF G W GV DEPLGKNDG+V
Sbjct: 200 SEAGSIKKGER-ELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVA 258
Query: 210 GKRYFECQAKYGAFVKPAVVTVGDFP 235
G RYF+CQ KYG F VT FP
Sbjct: 259 GTRYFQCQPKYGLFAPVHKVTKIGFP 284
Score = 68.2 bits (165), Expect = 6e-12
Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIG 194
E+ + ++A + ++ VG R V G P G + ++G T F PG W G
Sbjct: 34 EKTISSEKASSTPSSETQEEFVDDFRVGERVWVN--GNKP--GFIQFLGETQFAPGQWAG 89
Query: 195 VRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVT 230
+ DEP+GKNDGSV G RYF+C+ G F +P+ +T
Sbjct: 90 IVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 73.9 bits (180), Expect = 1e-13
Identities = 40/86 (46%), Positives = 50/86 (58%), Gaps = 5/86 (5%)
Query: 154 AQASSIPVGSRCEVRAAGQ----SPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVN 209
++A SI G R E++ + + G V ++G TDF G W GV DEPLGKNDG+V
Sbjct: 200 SEAGSIKKGER-ELKIGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVA 258
Query: 210 GKRYFECQAKYGAFVKPAVVTVGDFP 235
G RYF+CQ KYG F VT FP
Sbjct: 259 GTRYFQCQPKYGLFAPVHKVTKIGFP 284
Score = 68.2 bits (165), Expect = 6e-12
Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIG 194
E+ + ++A + ++ VG R V G P G + ++G T F PG W G
Sbjct: 34 EKTISSEKASSTPSSETQEEFVDDFRVGERVWVN--GNKP--GFIQFLGETQFAPGQWAG 89
Query: 195 VRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVT 230
+ DEP+GKNDGSV G RYF+C+ G F +P+ +T
Sbjct: 90 IVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 38/79 (48%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 153 KAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKR 212
+A A + VGSR EV G RGTV YVG T F G W+GV DE GKNDG+V G++
Sbjct: 21 EASARPLRVGSRVEVIGKGH---RGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRK 77
Query: 213 YFECQAKYGAFVKPAVVTV 231
YF C +G FV+ + + V
Sbjct: 78 YFTCDEGHGIFVRQSQIQV 96
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 73.6 bits (179), Expect = 2e-13
Identities = 38/79 (48%), Positives = 48/79 (60%), Gaps = 3/79 (3%)
Query: 153 KAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKR 212
+A A + VGSR EV G RGTV YVG T F G W+GV DE GKNDG+V G++
Sbjct: 21 EASARPLRVGSRVEVIGKGH---RGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRK 77
Query: 213 YFECQAKYGAFVKPAVVTV 231
YF C +G FV+ + + V
Sbjct: 78 YFTCDEGHGIFVRQSQIQV 96
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 73.6 bits (179), Expect = 2e-13
Identities = 37/94 (39%), Positives = 48/94 (51%)
Query: 136 EERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGV 195
E A Q LA + +A +P R + + G V YVG DF+ G W+GV
Sbjct: 1674 EGNAPAPGAGGQALASDSEEADEVPEWLREGEFVTVGAHKTGVVRYVGPADFQEGTWVGV 1733
Query: 196 RYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVV 229
D P GKNDGS+ GK+YF C YG V+P+ V
Sbjct: 1734 ELDLPSGKNDGSIGGKQYFRCNPGYGLLVRPSRV 1767
>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
[Homo sapiens]
Length = 1046
Score = 70.1 bits (170), Expect = 2e-12
Identities = 30/54 (55%), Positives = 37/54 (68%)
Query: 177 GTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVT 230
G V Y+G T F PG W GV D+P+GKNDG+V G RYFEC A G F +P+ +T
Sbjct: 93 GVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLT 146
Score = 68.9 bits (167), Expect = 4e-12
Identities = 30/49 (61%), Positives = 34/49 (69%)
Query: 175 RRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAF 223
+ G V YVG TDF G W GV DEPLGKNDG+V G RYF+C K+G F
Sbjct: 231 KTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLF 279
>gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2
[Homo sapiens]
Length = 1011
Score = 70.1 bits (170), Expect = 2e-12
Identities = 30/54 (55%), Positives = 37/54 (68%)
Query: 177 GTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPAVVT 230
G V Y+G T F PG W GV D+P+GKNDG+V G RYFEC A G F +P+ +T
Sbjct: 93 GVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLT 146
Score = 68.9 bits (167), Expect = 4e-12
Identities = 30/49 (61%), Positives = 34/49 (69%)
Query: 175 RRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKYGAF 223
+ G V YVG TDF G W GV DEPLGKNDG+V G RYF+C K+G F
Sbjct: 231 KTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLF 279
>gi|18496983 CAP-GLY domain containing linker protein 3 [Homo
sapiens]
Length = 547
Score = 69.7 bits (169), Expect = 2e-12
Identities = 43/135 (31%), Positives = 69/135 (51%), Gaps = 17/135 (12%)
Query: 96 GEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKL------GRYNEEERAQQEAEAAQRL 149
G + VS++ K A D +V S + ++ G+ E + +++ ++ L
Sbjct: 352 GLFASVSKISK------AVDAPPSSVTSTPRTPRMDFSRVTGKGRREHKGKKKTPSSPSL 405
Query: 150 AE-EKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSV 208
++ + VG +V AGQ ++G V + G TDF PGYW G+ D+P GK+DGSV
Sbjct: 406 GSLQQRDGAKAEVGD--QVLVAGQ--KQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSV 461
Query: 209 NGKRYFECQAKYGAF 223
G RYF C ++G F
Sbjct: 462 FGVRYFTCPPRHGVF 476
Score = 64.3 bits (155), Expect = 9e-11
Identities = 30/70 (42%), Positives = 39/70 (55%)
Query: 161 VGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNGKRYFECQAKY 220
+G R R + GT+ + G T+F G W+GV DEP GKNDGSV G RYF C K
Sbjct: 292 LGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQ 351
Query: 221 GAFVKPAVVT 230
G F + ++
Sbjct: 352 GLFASVSKIS 361
>gi|171184451 centrosome-associated protein 350 [Homo sapiens]
Length = 3117
Score = 55.8 bits (133), Expect = 3e-08
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 9/145 (6%)
Query: 91 SGAR-LGEYEDVSRV---EKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAA 146
SGA G E++S + +I + R ++S + K ++ E QQ E+
Sbjct: 2424 SGATSFGSNEEISECLSEKSLSIHSNVHSDRLLELKSPTELMKSKERSDVEHEQQVTESP 2483
Query: 147 QRLAEEKA-QASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKND 205
+ A + +G R + + + G + + G T F G+W GV D+P G N+
Sbjct: 2484 SLASVPTADELFDFHIGDRVLIG----NVQPGILRFKGETSFAKGFWAGVELDKPEGNNN 2539
Query: 206 GSVNGKRYFECQAKYGAFVKPAVVT 230
G+ +G YFEC+ K+G F P ++
Sbjct: 2540 GTYDGIAYFECKEKHGIFAPPQKIS 2564
>gi|118442828 beta-tubulin cofactor E [Homo sapiens]
Length = 527
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 21/94 (22%)
Query: 161 VGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEP-LGKNDGSVNGKRYFECQ-A 218
+G R EV TV + G+ G W+GV +D P GK+DGS G YF+C+
Sbjct: 10 IGRRVEVNG-----EHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHP 64
Query: 219 KYGAFVKPAVVTVG--------------DFPEED 238
G+F++P V G D PEED
Sbjct: 65 TGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEED 98
>gi|4507375 beta-tubulin cofactor E [Homo sapiens]
Length = 527
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 21/94 (22%)
Query: 161 VGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEP-LGKNDGSVNGKRYFECQ-A 218
+G R EV TV + G+ G W+GV +D P GK+DGS G YF+C+
Sbjct: 10 IGRRVEVNG-----EHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFKCRHP 64
Query: 219 KYGAFVKPAVVTVG--------------DFPEED 238
G+F++P V G D PEED
Sbjct: 65 TGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEED 98
>gi|109637774 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
[Homo sapiens]
Length = 953
Score = 35.8 bits (81), Expect = 0.035
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 136 EERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGV 195
EE + + LA + + VGS EV+ P G + ++G G+
Sbjct: 444 EELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE--NPPFYGVIRWIGQPPGLNEVLAGL 501
Query: 196 RY-DEPLGKNDGSVNGKRYFECQAKYGAFVK 225
DE G DG+ G RYF C K FVK
Sbjct: 502 ELEDECAGCTDGTFRGTRYFTCALKKALFVK 532
Score = 32.0 bits (71), Expect = 0.50
Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKP--GYW 192
E++ E++ A + + + + SR ++ G++ GTV++ + K GY+
Sbjct: 206 EDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV-GETIESGTVIFCDVLPGKESLGYF 264
Query: 193 IGVRYDEPLGKNDGSVNG 210
+GV D P+G DG +G
Sbjct: 265 VGVDMDNPIGNWDGRFDG 282
>gi|14165258 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
[Homo sapiens]
Length = 956
Score = 35.8 bits (81), Expect = 0.035
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 136 EERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGV 195
EE + + LA + + VGS EV+ P G + ++G G+
Sbjct: 447 EELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE--NPPFYGVIRWIGQPPGLNEVLAGL 504
Query: 196 RY-DEPLGKNDGSVNGKRYFECQAKYGAFVK 225
DE G DG+ G RYF C K FVK
Sbjct: 505 ELEDECAGCTDGTFRGTRYFTCALKKALFVK 535
Score = 32.0 bits (71), Expect = 0.50
Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKP--GYW 192
E++ E++ A + + + + SR ++ G++ GTV++ + K GY+
Sbjct: 206 EDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV-GETIESGTVIFCDVLPGKESLGYF 264
Query: 193 IGVRYDEPLGKNDGSVNG 210
+GV D P+G DG +G
Sbjct: 265 VGVDMDNPIGNWDGRFDG 282
>gi|109637776 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
[Homo sapiens]
Length = 953
Score = 35.8 bits (81), Expect = 0.035
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 136 EERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGV 195
EE + + LA + + VGS EV+ P G + ++G G+
Sbjct: 444 EELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKE--NPPFYGVIRWIGQPPGLNEVLAGL 501
Query: 196 RY-DEPLGKNDGSVNGKRYFECQAKYGAFVK 225
DE G DG+ G RYF C K FVK
Sbjct: 502 ELEDECAGCTDGTFRGTRYFTCALKKALFVK 532
Score = 32.0 bits (71), Expect = 0.50
Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKP--GYW 192
E++ E++ A + + + + SR ++ G++ GTV++ + K GY+
Sbjct: 206 EDDDTALESDYAGPGDTMQVELPPLEINSRVSLKV-GETIESGTVIFCDVLPGKESLGYF 264
Query: 193 IGVRYDEPLGKNDGSVNG 210
+GV D P+G DG +G
Sbjct: 265 VGVDMDNPIGNWDGRFDG 282
>gi|20357552 cortactin isoform a [Homo sapiens]
Length = 550
Score = 33.5 bits (75), Expect = 0.17
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 11/116 (9%)
Query: 62 KFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVE---KYTISQEAYDQRQ 118
K S+ D G Y V D +EDV++V + T+ EA +
Sbjct: 295 KHESQQDYSKGFGGKYGVQK-------DRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKT 347
Query: 119 DTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSP 174
+R+ + + +E+R + EAE AQR+A+E+ + + RA Q+P
Sbjct: 348 SNIRANFENLAKEK-EQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTP 402
>gi|20357556 cortactin isoform b [Homo sapiens]
Length = 513
Score = 33.1 bits (74), Expect = 0.23
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 89 DHSGARLGEYEDVSRVE---KYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEA 145
D +EDV++V + T+ EA + +R+ + + +E+R + EAE
Sbjct: 278 DRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEK-EQEDRRKAEAER 336
Query: 146 AQRLAEEKAQASSIPVGSRCEVRAAGQSP 174
AQR+A+E+ + + RA Q+P
Sbjct: 337 AQRMAKERQEQEEARRKLEEQARAKTQTP 365
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 33.1 bits (74), Expect = 0.23
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 95 LGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKA 154
L E +R++K QE ++ + + L+R +L R EEER + E EA ++ E K
Sbjct: 404 LAEKRRQARLQKEQEEQERVEKEE---QDRLEREELKRKAEEERLRLEEEARKQEEERKR 460
Query: 155 QASSIPVGSRCEVRAAGQSPRR 176
Q E R AG+ +R
Sbjct: 461 QEEEKKKQEGEEKRKAGEEAKR 482
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 30.4 bits (67), Expect = 1.5
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 130 LGRYNEEERAQQEAEAAQRLAEEKAQASSIPVG---SRCEVRAAGQSPRRGTVMYVGLTD 186
L Y+ ER + EA+ AQ+ AE+ Q ++ V S +V + GT + +
Sbjct: 849 LSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEE 908
Query: 187 FKPGYWIGVRYDEPL 201
P WI EPL
Sbjct: 909 RSPS-WISASVTEPL 922
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 30.4 bits (67), Expect = 1.5
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 130 LGRYNEEERAQQEAEAAQRLAEEKAQASSIPVG---SRCEVRAAGQSPRRGTVMYVGLTD 186
L Y+ ER + EA+ AQ+ AE+ Q ++ V S +V + GT + +
Sbjct: 751 LSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEE 810
Query: 187 FKPGYWIGVRYDEPL 201
P WI EPL
Sbjct: 811 RSPS-WISASVTEPL 824
>gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]
Length = 255
Score = 30.4 bits (67), Expect = 1.5
Identities = 12/24 (50%), Positives = 18/24 (75%)
Query: 73 LLGSYPVDDGCRIHVIDHSGARLG 96
+LGSY V+DG ++++ID SG G
Sbjct: 137 MLGSYSVNDGAQLYMIDPSGVSYG 160
>gi|6005757 chromatin-specific transcription elongation factor large
subunit [Homo sapiens]
Length = 1047
Score = 30.0 bits (66), Expect = 1.9
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 97 EYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQA 156
E E+ E Y+ E D ++++ S + K ++E E ++A+ R EE+ Q+
Sbjct: 956 EEEEEDSDEDYSSEAEESDYSKESLGSEEESGK--DWDELEEEARKADRESRYEEEEEQS 1013
Query: 157 SSIPVGSRCEVRAAGQSPRRGT 178
S+ + V ++G+ RG+
Sbjct: 1014 RSMSRKRKASVHSSGRGSNRGS 1035
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 30.0 bits (66), Expect = 1.9
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 12/97 (12%)
Query: 92 GARLGEYEDVSR------VEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEE-----ERAQ 140
G +LGE V +EK + Q +Q R + RS+L R+N + E+ +
Sbjct: 2245 GVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVE 2304
Query: 141 QEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRG 177
+E +R A AQA S+ + S+ + Q RG
Sbjct: 2305 RERRKLKREAMRAAQAGSLEI-SKATASSPTQQDGRG 2340
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 30.0 bits (66), Expect = 1.9
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 44 LVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSR 103
L GS A + E+ + +L++E LL + R+ A+ E E ++R
Sbjct: 170 LEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLE------AQAMELEALAR 223
Query: 104 VEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEK 153
EK A + +R+ L +++ R N EE +Q+E E QRL +E+
Sbjct: 224 AEK------AGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQ 267
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 30.0 bits (66), Expect = 1.9
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 44 LVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSR 103
L GS A + E+ + +L++E LL + R+ A+ E E ++R
Sbjct: 134 LEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLE------AQAMELEALAR 187
Query: 104 VEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEK 153
EK A + +R+ L +++ R N EE +Q+E E QRL +E+
Sbjct: 188 AEK------AGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQ 231
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 30.0 bits (66), Expect = 1.9
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 12/110 (10%)
Query: 44 LVGSPASCMELELYGVDDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGARLGEYEDVSR 103
L GS A + E+ + +L++E LL + R+ A+ E E ++R
Sbjct: 81 LEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLE------AQAMELEALAR 134
Query: 104 VEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEK 153
EK A + +R+ L +++ R N EE +Q+E E QRL +E+
Sbjct: 135 AEK------AGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQ 178
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 30.0 bits (66), Expect = 1.9
Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 5/53 (9%)
Query: 97 EYEDVS-RVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQR 148
E EDV+ +E+ T + A D++Q L+R+ R +EE Q+E EAAQR
Sbjct: 1473 ESEDVTLELERATSAAAALDKKQ----RHLERALEERRRQEEEMQRELEAAQR 1521
>gi|209862782 hypothetical protein LOC730130 [Homo sapiens]
Length = 380
Score = 30.0 bits (66), Expect = 1.9
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 19/104 (18%)
Query: 124 FLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRR------- 176
FLKR RY + R QQ+ + Q+ +++ A +P G+R AAG RR
Sbjct: 173 FLKRFLRLRYGRQRRRQQQQQQQQQ-QQQRRGALPVPPGARVPT-AAGARRRRPRGPRGA 230
Query: 177 GTVMYVGLTDFKPGYWIGVR----------YDEPLGKNDGSVNG 210
G GL D + G+ + LG+ DG+ +G
Sbjct: 231 GGAPSQGLPDLPRFLFFGMHGFLDEIFFTFFFNVLGQGDGTTSG 274
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 29.6 bits (65), Expect = 2.5
Identities = 19/87 (21%), Positives = 40/87 (45%)
Query: 80 DDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERA 139
D+ RI + + A+ E + E+ ++ + + ++ KR+ R +E
Sbjct: 290 DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE 349
Query: 140 QQEAEAAQRLAEEKAQASSIPVGSRCE 166
++ AE QR+ EE+ +A+ +R E
Sbjct: 350 KRAAEERQRIKEEEKRAAEERQRARAE 376
Score = 28.1 bits (61), Expect = 7.3
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 75 GSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYN 134
G+ V+ G R+ + R GE E + QEA + ++ + +R K+
Sbjct: 526 GAPQVEAGKRLEELRR---RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 582
Query: 135 EEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFK 188
E+ R Q+EA+ R EEK + + E R A + +R + GL+D K
Sbjct: 583 EQRRKQEEADRKLREEEEKRR-----LKEEIERRRAEAAEKRQKMPEDGLSDDK 631
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,064,257
Number of Sequences: 37866
Number of extensions: 401161
Number of successful extensions: 1788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 1651
Number of HSP's gapped (non-prelim): 177
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.