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Search of human proteins with 5032033
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032033 RNA binding motif protein 6 [Homo sapiens]
(1123 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032033 RNA binding motif protein 6 [Homo sapiens] 2333 0.0
gi|5032031 RNA binding motif protein 5 [Homo sapiens] 224 4e-58
gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens] 193 9e-49
gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens] 193 9e-49
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 58 4e-08
gi|148746195 trichohyalin [Homo sapiens] 53 1e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 2e-06
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform... 51 5e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 49 2e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 49 3e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 49 3e-05
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 48 6e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 8e-05
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 46 2e-04
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 46 2e-04
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 46 2e-04
gi|125656165 THO complex 2 [Homo sapiens] 46 2e-04
gi|4826972 RNA binding motif protein 8A [Homo sapiens] 45 3e-04
gi|171916097 repetin [Homo sapiens] 45 3e-04
gi|70608155 phosphodiesterase 3A [Homo sapiens] 45 4e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 45 4e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 4e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 44 9e-04
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 44 9e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 44 9e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 44 0.001
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 44 0.001
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 43 0.001
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 43 0.001
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 43 0.001
>gi|5032033 RNA binding motif protein 6 [Homo sapiens]
Length = 1123
Score = 2333 bits (6045), Expect = 0.0
Identities = 1123/1123 (100%), Positives = 1123/1123 (100%)
Query: 1 MWGDSRPANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGRDSLPFDFQGH 60
MWGDSRPANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGRDSLPFDFQGH
Sbjct: 1 MWGDSRPANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHSGNFPGRDSLPFDFQGH 60
Query: 61 SGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFSSSDFQSRDSSQLDFRGRDI 120
SGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFSSSDFQSRDSSQLDFRGRDI
Sbjct: 61 SGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFSSSDFQSRDSSQLDFRGRDI 120
Query: 121 HSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDAHAVDFRGRDAPPSDFRGRGT 180
HSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDAHAVDFRGRDAPPSDFRGRGT
Sbjct: 121 HSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDAHAVDFRGRDAPPSDFRGRGT 180
Query: 181 YDLDFRGRDGSHADFRGRDLSDLDFRAREQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGS 240
YDLDFRGRDGSHADFRGRDLSDLDFRAREQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGS
Sbjct: 181 YDLDFRGRDGSHADFRGRDLSDLDFRAREQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGS 240
Query: 241 GTTDLDFRDRDTPHSDFRGRHRSRTDQDFRGREMGSCMEFKDREMPPVDPNILDYIQPST 300
GTTDLDFRDRDTPHSDFRGRHRSRTDQDFRGREMGSCMEFKDREMPPVDPNILDYIQPST
Sbjct: 241 GTTDLDFRDRDTPHSDFRGRHRSRTDQDFRGREMGSCMEFKDREMPPVDPNILDYIQPST 300
Query: 301 QDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFEHESPADFQNS 360
QDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFEHESPADFQNS
Sbjct: 301 QDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFEHESPADFQNS 360
Query: 361 QSPVQDQDKSQLSGREEQSSDAGLFKEEGGLDFLGRQDTDYRSMEYRDVDHRLPGSQMFG 420
QSPVQDQDKSQLSGREEQSSDAGLFKEEGGLDFLGRQDTDYRSMEYRDVDHRLPGSQMFG
Sbjct: 361 QSPVQDQDKSQLSGREEQSSDAGLFKEEGGLDFLGRQDTDYRSMEYRDVDHRLPGSQMFG 420
Query: 421 YGQSKSFPEGKTARDAQRDLQDQDYRTGPSEEKPSRLIRLSGVPEDATKEEILNAFRTPD 480
YGQSKSFPEGKTARDAQRDLQDQDYRTGPSEEKPSRLIRLSGVPEDATKEEILNAFRTPD
Sbjct: 421 YGQSKSFPEGKTARDAQRDLQDQDYRTGPSEEKPSRLIRLSGVPEDATKEEILNAFRTPD 480
Query: 481 GMPVKNLQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIQDKEVTLEYVSSLDFW 540
GMPVKNLQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIQDKEVTLEYVSSLDFW
Sbjct: 481 GMPVKNLQLKEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLMIQDKEVTLEYVSSLDFW 540
Query: 541 YCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADK 600
YCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADK
Sbjct: 541 YCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADK 600
Query: 601 EPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIML 660
EPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIML
Sbjct: 601 EPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIML 660
Query: 661 KRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQ 720
KRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQ
Sbjct: 661 KRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQ 720
Query: 721 NLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNR 780
NLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNR
Sbjct: 721 NLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNR 780
Query: 781 QGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGK 840
QGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGK
Sbjct: 781 QGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGK 840
Query: 841 SSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNP 900
SSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNP
Sbjct: 841 SSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNP 900
Query: 901 LIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLC 960
LIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLC
Sbjct: 901 LIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLC 960
Query: 961 RRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKL 1020
RRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKL
Sbjct: 961 RRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKL 1020
Query: 1021 QSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASS 1080
QSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASS
Sbjct: 1021 QSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASS 1080
Query: 1081 EEAEGRMRGPSVGASGRTSKRQSNETYRDAVRRVMFARYKELD 1123
EEAEGRMRGPSVGASGRTSKRQSNETYRDAVRRVMFARYKELD
Sbjct: 1081 EEAEGRMRGPSVGASGRTSKRQSNETYRDAVRRVMFARYKELD 1123
>gi|5032031 RNA binding motif protein 5 [Homo sapiens]
Length = 815
Score = 224 bits (571), Expect = 4e-58
Identities = 145/374 (38%), Positives = 201/374 (53%), Gaps = 60/374 (16%)
Query: 790 YIYDSATGYYYDPLAGTYYDPNTQ----------------QEVYVP-------QDPGLPE 826
Y YD ++GYYYDP G YYDPN+Q +E YVP Q GLP
Sbjct: 462 YQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQSGLPP 521
Query: 827 EEEIKEKKPTSQGKSSSK--KEM---SKRDGKEKKD-----RGVTRFQENASEGKAPAED 876
+E KEKK + K++ + K+M +K K+K++ + V +E A A+
Sbjct: 522 AKEGKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADA 581
Query: 877 VFKKPLPPTVKKEESPPPPKVV------NPLI-GLLGEYGGDSDYEEEEEEEQTPPPQPR 929
F E P++V NPL GL+ Y GDSD EEE E
Sbjct: 582 GFALFEKKGALAERQQLIPELVRNGDEENPLKRGLVAAYSGDSDNEEELVE--------- 632
Query: 930 TAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRK 989
+ E+EE+KL DW K+ACLLCRRQFPNK+ L++HQQLSDLHKQN++I+R+
Sbjct: 633 -----------RLESEEEKLADWKKMACLLCRRQFPNKDALVRHQQLSDLHKQNMDIYRR 681
Query: 990 IKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDI 1049
+ SEQEL LE RERE K++ R +RREK + PE KR K + + K+ I
Sbjct: 682 SRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAGTVNYEQPTKDGI 741
Query: 1050 DTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYRD 1109
D S+ G + QA GWR+G+GLG G+ + EA+ R++G +GA G ++Y+D
Sbjct: 742 DHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKD 801
Query: 1110 AVRRVMFARYKELD 1123
AVR+ MFAR+ E++
Sbjct: 802 AVRKAMFARFTEME 815
Score = 73.9 bits (180), Expect = 8e-13
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 17/176 (9%)
Query: 396 RQDTDYRSMEYRDVDHRLPGSQMFGYGQSKSFPEGKTARDAQR---------DLQDQDYR 446
R+D+DY+ R D R G + Y S + R++ R D + DYR
Sbjct: 34 RRDSDYK----RSSDDRR-GDRYDDYRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYR 88
Query: 447 TGPSEEKPSRLIRLSGVPEDATKEEILNAFRTPDGMPVKNLQLKEYNTGYDYGYVCVEFS 506
S+E+ S+ I L G+P T+ +I + +G +++L + TG G+ VEF
Sbjct: 89 HDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFY 148
Query: 507 LLEDAIGCMEANQGTLMIQDKEVTLEYVS---SLDFWYCKRCKANIGGHRSSCSFC 559
L+DA MEANQ L+IQ K + + Y + + W C +C N R C C
Sbjct: 149 HLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRC 204
Score = 66.2 bits (160), Expect = 2e-10
Identities = 47/165 (28%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 639 DRERESWSGETRQ----DGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRT 694
D E+E G T D TI+L+ I T + I+ L PY L N+R+IK++
Sbjct: 210 DSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQ 269
Query: 695 GPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMH 754
+ F+ L S +A ++++ILQ+L PP IDGK + V+ A R++ + +
Sbjct: 270 TQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLSDGNRV- 328
Query: 755 YYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSD-CYIYDSATGY 798
F + WSS ++ G+ S D Y+ GY
Sbjct: 329 -----SAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYLQPGQDGY 368
Score = 36.6 bits (83), Expect = 0.14
Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 28/156 (17%)
Query: 601 EPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDG------- 653
E E R R + + R +RY + P +RERE + + +DG
Sbjct: 27 ERESRSRRRDSDYKRSSDDRRGDRYDDYRDYDSP----ERERERRNSDRSEDGYHSDGDY 82
Query: 654 -------------ESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHT 700
ESKTIML+ + + I E++E + A+VR++K +TG +
Sbjct: 83 GEHDYRHDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTG-VSRG 141
Query: 701 YGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVN 736
+ F++ +A ++ Q I GK +A++
Sbjct: 142 FAFVEFYHLQDATSWMEANQK---KLVIQGKHIAMH 174
>gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens]
Length = 930
Score = 193 bits (490), Expect = 9e-49
Identities = 133/384 (34%), Positives = 191/384 (49%), Gaps = 79/384 (20%)
Query: 790 YIYDSATGYYYDPLAGTYYDPNTQ----------------QEVYVP---------QDPGL 824
Y YD +GYYYDP G YYDPN+Q + YVP ++ G
Sbjct: 572 YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA 631
Query: 825 PEEEEIKEKKPTSQGKSSSK--KEMSK--RDGKEKKDRGVTRFQENAS------------ 868
P +E KEKK + K++ + K+M + R ++K+ FQ +S
Sbjct: 632 PSKEG-KEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA 690
Query: 869 --------EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEE 920
+ A AE P + ++ P PP+ GL+ Y G+SD EEE+E
Sbjct: 691 DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPR------GLVAAYSGESDSEEEQER 744
Query: 921 EQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH 980
P++ E+KLTDW KLACLLCRRQFP+KE LI+HQQLS LH
Sbjct: 745 ----------GGPER----------EEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLH 784
Query: 981 KQNLEIHRKIKQSEQELAYLERREREG-KFKGRGNDRREKLQSFDSPERKRIKYS--RET 1037
KQNLEIHR+ SE EL LE+ + E K++ R +RREK + PE KR KY
Sbjct: 785 KQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTA 844
Query: 1038 DSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGR 1097
D + ++ + + + G + QA GW++G+GLG G+ + EA+ R+RG +GA G
Sbjct: 845 SVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGS 904
Query: 1098 TSKRQSNETYRDAVRRVMFARYKE 1121
+ S E+Y++ + + M R+ E
Sbjct: 905 SYGVTSTESYKETLHKTMVTRFNE 928
Score = 117 bits (292), Expect = 8e-26
Identities = 109/405 (26%), Positives = 182/405 (44%), Gaps = 64/405 (15%)
Query: 368 DKSQLSGREEQSSD--------AGLFKEEGGLDFLGRQDTDYRSMEYRDVD--HRLPGS- 416
D+SQ G E +S D +E G + G+ D D S E D PGS
Sbjct: 20 DRSQDDGGENRSRDHDYRDMDYRSYPREYGSQE--GKHDYDDSSEEQSAEDSYEASPGSE 77
Query: 417 -QMFGYGQSKSFPEGKTARDAQRDLQDQDYRTGPSEE-----------KPSRLIRLSGVP 464
Q + + P G D +DQDYRT EE K S ++ L +P
Sbjct: 78 TQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLP 137
Query: 465 EDATKEEILNAFRTPDGMPVKNLQL-KEYNTGYDYGYVCVEFSLLEDAIGCMEANQGTLM 523
+ AT+++I ++ G+ + ++L + ++G G+ VEFS L+DA MEANQ +L
Sbjct: 138 QAATEDDIRGQLQS-HGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLN 196
Query: 524 IQDKEVTLEYVSSL----DFWYCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQPQ 579
I ++V++ Y + W C +C R C C P+ +EA+Q+L +
Sbjct: 197 ILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK--SEAEQKLPLGTRLD 254
Query: 580 KTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRD 639
+ ++P ++ +Q L P P+P + + S
Sbjct: 255 QQTLPLG-GRELSQGLLPL---PQPYQAQGVLAS-------------------------- 284
Query: 640 RERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGH 699
+ S E + + TI+L+ + + + I+ L PY L+++NVR+IK++ +
Sbjct: 285 -QALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNR 343
Query: 700 TYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRN 744
+ FI L + EA ++++ILQ L PP +IDGK + V A G +R+
Sbjct: 344 GFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRD 388
>gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens]
Length = 852
Score = 193 bits (490), Expect = 9e-49
Identities = 133/384 (34%), Positives = 191/384 (49%), Gaps = 79/384 (20%)
Query: 790 YIYDSATGYYYDPLAGTYYDPNTQ----------------QEVYVP---------QDPGL 824
Y YD +GYYYDP G YYDPN+Q + YVP ++ G
Sbjct: 494 YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA 553
Query: 825 PEEEEIKEKKPTSQGKSSSK--KEMSK--RDGKEKKDRGVTRFQENAS------------ 868
P +E KEKK + K++ + K+M + R ++K+ FQ +S
Sbjct: 554 PSKEG-KEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA 612
Query: 869 --------EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEE 920
+ A AE P + ++ P PP+ GL+ Y G+SD EEE+E
Sbjct: 613 DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPR------GLVAAYSGESDSEEEQER 666
Query: 921 EQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH 980
P++ E+KLTDW KLACLLCRRQFP+KE LI+HQQLS LH
Sbjct: 667 ----------GGPER----------EEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLH 706
Query: 981 KQNLEIHRKIKQSEQELAYLERREREG-KFKGRGNDRREKLQSFDSPERKRIKYS--RET 1037
KQNLEIHR+ SE EL LE+ + E K++ R +RREK + PE KR KY
Sbjct: 707 KQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTA 766
Query: 1038 DSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGR 1097
D + ++ + + + G + QA GW++G+GLG G+ + EA+ R+RG +GA G
Sbjct: 767 SVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGS 826
Query: 1098 TSKRQSNETYRDAVRRVMFARYKE 1121
+ S E+Y++ + + M R+ E
Sbjct: 827 SYGVTSTESYKETLHKTMVTRFNE 850
Score = 99.0 bits (245), Expect = 2e-20
Identities = 95/347 (27%), Positives = 151/347 (43%), Gaps = 43/347 (12%)
Query: 404 MEYRDVDHRLPGSQMFGYGQS-KSFPEGKTARDAQRDLQDQDYRTGPSEEKPSRLIRLSG 462
MEY R G + YG + +S +G R D +D DYR+ P E
Sbjct: 1 MEYERRGGR--GDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYD 58
Query: 463 VPEDATKEEILNAFRTPDGMPVKNLQL-KEYNTGYDYGYVCVEFSLLEDAIGCMEANQGT 521
+ EI ++ G+ + ++L + ++G G+ VEFS L+DA MEANQ +
Sbjct: 59 DSSEEQSAEIRGQLQS-HGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHS 117
Query: 522 LMIQDKEVTLEYVSSL----DFWYCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQ 577
L I ++V++ Y + W C +C R C C P+ E K L T
Sbjct: 118 LNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLD 177
Query: 578 PQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFR 637
Q + ++ +Q L P P+P + + S+ Q E
Sbjct: 178 QQTLPLGG---RELSQGLLPL---PQPYQAQGVLASQALSQGSEP--------------- 216
Query: 638 RDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPM 697
S E D TI+L+ + + + I+ L PY L+++NVR+IK++ +
Sbjct: 217 --------SSENAND----TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQL 264
Query: 698 GHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRN 744
+ FI L S EA ++++ILQ L PP +IDGK + V A G +R+
Sbjct: 265 NRGFAFIQL-STIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRD 310
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 58.2 bits (139), Expect = 4e-08
Identities = 62/248 (25%), Positives = 105/248 (42%), Gaps = 39/248 (15%)
Query: 814 QEVYVPQDPGLPEEEEIKEKKPTSQGKSSS-KKEMSKRDGKEKKDRGVTRFQENASEGKA 872
+E+ V EE+ +KEK+ Q + KK+ R G+ KKD ++ E K
Sbjct: 43 EELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKD------VDDDGEEKE 96
Query: 873 PAEDVFKKPLPPTVKKEESPPPP-------KVVNPLIGLLGEYGGDSDYEEEEEEEQTPP 925
E + K +P + +++E P P K N L+ D EEEEEE+ P
Sbjct: 97 LMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALI------QDQSEEEEEEEKHP 150
Query: 926 PQP-------------RTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIK 972
P+P QP + ++ K+E + K NK A L + +E++ +
Sbjct: 151 PKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKE 210
Query: 973 HQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPE-RKRI 1031
+ KQ E +K +Q +E E E EG + + +D L + + +K++
Sbjct: 211 KEP----PKQGKEKAKKAEQGSEEEGEGEEEEEEGG-ESKADDPYAHLSKKEKKKLKKQM 265
Query: 1032 KYSRETDS 1039
+Y R+ S
Sbjct: 266 EYERQVAS 273
Score = 36.2 bits (82), Expect = 0.18
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E++E K K+ + GKS+ + E ++ +K + R +N E A ++ K+P T
Sbjct: 552 EKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRR--KNQDEESQEAPELLKRPKEYT 609
Query: 886 VKKEESPPPPKVVNPLIGLLG 906
V + P PP + P++GL G
Sbjct: 610 V-RFTFPDPPPLSPPVLGLHG 629
Score = 34.3 bits (77), Expect = 0.68
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVF------- 878
EEE IKEK+P QGK +KK G E++ G +E G++ A+D +
Sbjct: 204 EEEIIKEKEPPKQGKEKAKK---AEQGSEEEGEGE---EEEEEGGESKADDPYAHLSKKE 257
Query: 879 KKPLPPTVKKEESPPPPKVVN 899
KK L ++ E K N
Sbjct: 258 KKKLKKQMEYERQVASLKAAN 278
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 8/136 (5%)
Query: 915 EEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQ 974
EE E+++ Q R Q ++RE++ K++ EE++L + L R Q +E L+K +
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 975 QLSDLHKQNLEIHRKIKQSEQELAYLERRE--REGKFKGRGNDR------REKLQSFDSP 1026
+ L ++ E K +Q E+ L+R E R+ + K +R RE+++ +
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 1027 ERKRIKYSRETDSDRK 1042
ER+ + RE + +
Sbjct: 614 ERREQRLKREEPEEER 629
Score = 49.7 bits (117), Expect = 2e-05
Identities = 57/269 (21%), Positives = 112/269 (41%), Gaps = 55/269 (20%)
Query: 809 DPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENAS 868
D ++ + +D PEEE+++ ++ +KE +RD K ++++ + R +
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREE---------QKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 869 EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEE---------- 918
+ + F++ ++EE P L D + EEE
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQP------------LRRQERDRKFREEELRHQEQGRKF 1376
Query: 919 -EEEQTPPPQPRTAQPQKREEQTKKENEEDKL---------TDWNKLACLLCRRQFPNKE 968
EEEQ Q R + K E+Q + + E +L + +L+ R+F +E
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 969 VLIKHQQ-----LSDLHKQNLEIHRKIKQSEQ-----ELAYLERREREGKFKGRGNDRRE 1018
++ Q+ L + + E HRK ++ EQ E L R+ER+ KF + +
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL----EEEQ 1492
Query: 1019 KLQSFDSPERKRIKYSRETDSDRKLVDKE 1047
+L+ + + R + R + +RK +++E
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEE 1521
Score = 46.6 bits (109), Expect = 1e-04
Identities = 38/132 (28%), Positives = 67/132 (50%), Gaps = 15/132 (11%)
Query: 919 EEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSD 978
EEEQ Q R + ++ E+Q +++ E K + + R+F +E L++ ++
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 979 LHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRE-- 1036
LH+Q E RK + EQ+L R+ER+ KF R ++L+S PERK ++ ++
Sbjct: 1478 LHRQ--ERDRKFLEEEQQL---RRQERDRKF------REQELRS-QEPERKFLEEEQQLH 1525
Query: 1037 -TDSDRKLVDKE 1047
RK + +E
Sbjct: 1526 RQQRQRKFLQEE 1537
Score = 45.4 bits (106), Expect = 3e-04
Identities = 53/235 (22%), Positives = 102/235 (43%), Gaps = 35/235 (14%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
+E + E + + + ++ +RD K ++D + + +E + + F + P
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEE-----EEQTPPPQPRTAQPQKREEQT 940
++E + D + EEE+ EEQ Q R + ++ E+Q
Sbjct: 1653 RRQEREQQL------------RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 941 KKENEEDK-LTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQ---- 995
+++ E K L + +L R+F +E L + + L +Q E +RKI + EQ
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ--ERYRKILEEEQLRPE 1758
Query: 996 -ELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDI 1049
E L R+ER+ KF+ R+E+ E +++ R +SDRK ++E +
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQER-------EEQQL---RSQESDRKFREEEQL 1803
Score = 40.8 bits (94), Expect = 0.007
Identities = 48/241 (19%), Positives = 106/241 (43%), Gaps = 20/241 (8%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E+EE + ++ + + +++ +R+ + ++++ + R Q+ E + E ++
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 886 VKKEESPPPPKVVNPLIG--LLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTK-- 941
++EE K L E D+ + EEE + Q R Q KR+++ +
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE-QERRKQQLKRDQEEERR 485
Query: 942 ----KENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQEL 997
K EE++ + L R Q +E +K Q+ + +Q L +++++ ++E
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 998 ----------AYLERREREGKFKGRGNDRREKLQSFDSPER-KRIKYSRETDSDRKLVDK 1046
LE+ RE + K +RR++L + R +R+K +E +++L +
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 1047 E 1047
E
Sbjct: 606 E 606
Score = 40.0 bits (92), Expect = 0.012
Identities = 51/243 (20%), Positives = 109/243 (44%), Gaps = 18/243 (7%)
Query: 809 DPNTQQEVYVPQDP--GLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQEN 866
+P Q+E+ ++ L +E +E++ Q + ++E R +E++ R +
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 867 ASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPP 926
E + E+ ++ L +++E ++ E + EEE E+Q
Sbjct: 324 QQERREQQEERREQQLR---REQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 927 QP-RTAQPQKREEQTKKENE---EDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQ 982
Q R Q +RE+Q ++E + E +L +L R Q +E ++ +Q + H+Q
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLR----REQQLRREQQLRREQEEERHEQ 436
Query: 983 NLEIHRKIKQSEQELAYLERRE---REGKFKGRGNDRREKLQSFDSPERKRIKYSRETDS 1039
E R+ ++ ++E ERR+ RE + + +RR++ D E +R ++ + +
Sbjct: 437 KHEQERREQRLKREQE--ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 1040 DRK 1042
+R+
Sbjct: 495 ERR 497
Score = 40.0 bits (92), Expect = 0.012
Identities = 42/242 (17%), Positives = 101/242 (41%), Gaps = 40/242 (16%)
Query: 807 YYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQEN 866
Y P Q+++ Q EEEE++ ++ + + +++ + + ++++ + R +E
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR-EER 948
Query: 867 ASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPP 926
+ E ++K K+E+ LLGE + E+ +E+
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQ-------------LLGE-----EPEKRRRQEREKKY 990
Query: 927 QPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEI 986
+ Q+ E+ ++E E+ + +W RQ+ K+ L + ++
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWE--------RQYRKKDELQQEEE----------- 1031
Query: 987 HRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDK 1046
++ + E+E L+ RER+ + + E+L + R+R + R+ + +L +
Sbjct: 1032 --QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089
Query: 1047 ED 1048
E+
Sbjct: 1090 EE 1091
Score = 39.7 bits (91), Expect = 0.016
Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 11/133 (8%)
Query: 916 EEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQ 975
+EEE+ + R +Q Q+R+++ + + EE++ + L ++ KE + ++
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 976 LSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSR 1035
+L ++ E K ++ EQE Y E + + + + + REK R+R + R
Sbjct: 910 EEELQREERE---KRRRQEQERQYREEEQLQQEEEQLLREEREK--------RRRQERER 958
Query: 1036 ETDSDRKLVDKED 1048
+ D+KL KE+
Sbjct: 959 QYRKDKKLQQKEE 971
Score = 39.7 bits (91), Expect = 0.016
Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 22/142 (15%)
Query: 917 EEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQL 976
+E EEQ Q R + + E+Q +++ + K + R Q P ++ L + QQL
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE------LRSQEPERKFLEEEQQL 1524
Query: 977 SDLHKQNLEIHRKIKQSEQELAYLER-----REREGKFKGRGNDRREKLQSFDSPERKRI 1031
H+Q + RK Q EQ+L ER ++R+ KF+ R+E+ + S + +
Sbjct: 1525 ---HRQQRQ--RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Query: 1032 KYS------RETDSDRKLVDKE 1047
K+ R + +RK ++ E
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDE 1601
Score = 38.5 bits (88), Expect = 0.036
Identities = 46/247 (18%), Positives = 111/247 (44%), Gaps = 42/247 (17%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
++E + ++P +E +E++ + + ++E R+ +EK+ R Q E
Sbjct: 1089 EEEQLLREEPEKRRRQE-RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 873 PAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQ 932
E+ + P +++E + Y EEEE +Q R Q
Sbjct: 1148 QEEEQLLREEPEKRRRQEL-------------------ERQYREEEELQQEEEQLLREEQ 1188
Query: 933 PQKREEQTKKENEEDKL---------TDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQN 983
++R+E+ ++ EE++L D ++ + L + + P KE ++ ++ ++N
Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE-PEKENAVRDNKVYCKGREN 1247
Query: 984 LEIHR------KIKQSEQELAYL--ERREREGKFKGRGNDRREKLQSFDSPERKRIKYSR 1035
+ + + +QS+Q+L +L E++ER+ + + R +R++ PE ++++
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR----HFPEEEQLEREE 1303
Query: 1036 ETDSDRK 1042
+ ++ R+
Sbjct: 1304 QKEAKRR 1310
Score = 38.1 bits (87), Expect = 0.047
Identities = 46/229 (20%), Positives = 100/229 (43%), Gaps = 31/229 (13%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
QQE Q +EE +++ Q + ++++ + +E++++ + R Q+ E +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 873 PAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQ 932
E ++ +++E+ + + L E + EEE E++ +
Sbjct: 390 RREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH--------E 439
Query: 933 PQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQ 992
++RE++ K+E EE DW K +E +H+Q + KQ L+ ++ ++
Sbjct: 440 QERREQRLKREQEER--RDWLK-----------REEETERHEQ--ERRKQQLKRDQEEER 484
Query: 993 SEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDR 1041
E+ L E RE + +RRE+ + ER+ + R+ + +R
Sbjct: 485 RERWLKLEEEERREQQ------ERREQQLRREQEERREQRLKRQEEEER 527
Score = 38.1 bits (87), Expect = 0.047
Identities = 56/236 (23%), Positives = 104/236 (44%), Gaps = 34/236 (14%)
Query: 824 LPEEEEIKEKKPTSQGKSSS---KKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKK 880
L EEE+++ ++ Q + +++ +R +E++ R+Q E K ++ K
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE-EERKRRRHTLYAK 892
Query: 881 P-LPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKR--- 936
P L ++KE+ LL +EEEEE Q + R Q Q+R
Sbjct: 893 PALQEQLRKEQQ------------LL---------QEEEEELQREEREKRRRQEQERQYR 931
Query: 937 -EEQTKKENEEDKLTDWNKLACLLCRRQF-PNKEVLIKHQQL--SDLHKQNLEIHRKIKQ 992
EEQ ++E E+ + K RQ+ +K++ K +QL + K+ + K +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 993 SEQELAYLERR-EREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKE 1047
E+EL E + RE + K R + + + D +++ + RE R+L ++E
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Score = 37.7 bits (86), Expect = 0.062
Identities = 51/237 (21%), Positives = 100/237 (42%), Gaps = 31/237 (13%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
QQ++ +D E+E++ +++ Q +RD K ++ R QE + +
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQ------LHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 873 PAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQ 932
+ F++ + EE L D + EEE++ + + + Q
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQ------------LRRQERDRKFREEEQQLRRQERERKFLQ 1711
Query: 933 PQ---KREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNL---EI 986
+ +R+E +K EE++L + L RRQ +++L + Q + +Q L E
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQL--RRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 987 HRKIKQSEQ-----ELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETD 1038
RK ++ EQ E L +E + KF+ R+E+ + P+++ KY E +
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Score = 37.4 bits (85), Expect = 0.081
Identities = 49/250 (19%), Positives = 115/250 (46%), Gaps = 39/250 (15%)
Query: 808 YDPNTQQEVYVPQDPGLPEEEEIKEK-KPTSQGKSSSKKE--MSKRDGKEKKDRGVTRFQ 864
++P +Q + ++PG ++ +E+ + ++G+ S+K+ + +RD ++++D + R +
Sbjct: 122 FEPRDRQ---LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD-RQRRDEELWRQR 177
Query: 865 ENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEE-------- 916
+ E + + + + EE P ++ + L G + ++
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 917 -EEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQ 975
+EEEE+ + R+ +T EE+KL + +RQ +E+ + +Q
Sbjct: 238 FQEEEEK-----------EWRKRETVLRKEEEKLQEEEP------QRQ---RELQEEEEQ 277
Query: 976 LSDLHKQNLEIHRKIKQSEQELAYLE---RREREGKFKGRGNDRREKLQSFDSPERKRIK 1032
L L +Q L R+ ++ +Q+ E RR++E + + + +RRE+ + + E +R +
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 1033 YSRETDSDRK 1042
R +R+
Sbjct: 338 QLRREQEERR 347
Score = 37.0 bits (84), Expect = 0.11
Identities = 43/225 (19%), Positives = 98/225 (43%), Gaps = 38/225 (16%)
Query: 828 EEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVK 887
E++ +++ + + +++ KR+ +E++D+ + R +E + ++ + L +K
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE---ERLEQRLK 603
Query: 888 KEESPPPPKVVNPLIGLLGEYGGDSDYEE---EEEEEQTPPPQPRTAQPQKREEQTKKEN 944
+EE + L E + ++ EE+E+ Q R Q ++RE++ K+E
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Query: 945 EEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRE 1004
EE++L +Q L+ + ++ EQELA E+ +
Sbjct: 664 EEERL-------------------------------EQRLKREHEEERREQELAEEEQEQ 692
Query: 1005 REGKFKGRGNDRREKLQS-FDSPERKRIKYSRETDSDRKLVDKED 1048
+ K R + +L+S D+ + K R+ + R+ ++E+
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Score = 36.6 bits (83), Expect = 0.14
Identities = 45/257 (17%), Positives = 114/257 (44%), Gaps = 25/257 (9%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
+++ Y ++ EEE++ ++ + + +++ K+D ++++ + R +E
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR-EEREKRRLQ 1044
Query: 873 PAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQ 932
E +++ ++E+ + L +Y + + ++EEE+ P+ R +
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR--R 1102
Query: 933 PQKREEQTKKE----NEEDKL--TDWNKLACLLCRRQFPNKEVL--------------IK 972
Q+RE Q ++E EE++L + K RQ+ +E + +
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 973 HQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQS--FDSPERKR 1030
Q+L +++ E+ ++ +Q +E R+ERE +++ +R+K + D +R
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 1031 IKYSRETDSDRKLVDKE 1047
+K+ E + + + D +
Sbjct: 1223 LKWQWEPEKENAVRDNK 1239
Score = 33.9 bits (76), Expect = 0.89
Identities = 27/122 (22%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
Query: 918 EEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLS 977
EEE+ P + + + Q+R+ + ++E + + + +L R+F +E L + ++
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 978 DLHKQNLE-----IHRKIKQSEQELAYLERRER----EGKFKGRGNDRREKLQSFDSPER 1028
L Q + +++ EQE + R+R E +F + RRE+ + + E+
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 1029 KR 1030
KR
Sbjct: 1871 KR 1872
Score = 33.5 bits (75), Expect = 1.2
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 17/139 (12%)
Query: 918 EEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLS 977
EEE+Q Q + Q+ ++ ++E + + D + R+F +E L + ++
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD--------RKFREEEQLRQEREEQ 1570
Query: 978 DLHKQNLEI-----HRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPER---- 1028
L +Q + +K+++ EQE ++E ++ + +G+ R+E+ + F E+
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 1029 KRIKYSRETDSDRKLVDKE 1047
+ + + DRK +++E
Sbjct: 1631 REEQQLHRQERDRKFLEEE 1649
Score = 32.7 bits (73), Expect = 2.0
Identities = 43/231 (18%), Positives = 100/231 (43%), Gaps = 34/231 (14%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
Q++ + ++ EEE+++ K + ++++ +R+ E + +G Q+ E +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ- 234
Query: 873 PAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQ 932
+ VF++ +K E+ + EE+ +EE+ PQ R +
Sbjct: 235 --DRVFQEEEEKEWRKRETVLRKE------------------EEKLQEEE---PQ-RQRE 270
Query: 933 PQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQ 992
Q+ EEQ +K ++ + + + ++ L + QQL ++ ++ ++
Sbjct: 271 LQEEEEQLRKLERQELRRE--------RQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 993 SEQELAYLERREREGKFKGRGNDRRE-KLQSFDSPERKRIKYSRETDSDRK 1042
+QE + RE + + +RRE +L+ ER+ + RE + +R+
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Score = 32.7 bits (73), Expect = 2.0
Identities = 51/251 (20%), Positives = 111/251 (44%), Gaps = 18/251 (7%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKK---DRGVTRFQENASEGKAPAEDVFKKPLP 883
E+E++ ++P + K +++ R +++K + R QE + + + F++
Sbjct: 1505 EQELRSQEP--ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 884 PTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEE--EEEEQTPPPQPRTAQPQKREEQTK 941
++EE + + L + + E + E+E+Q + + Q Q R+E+ +
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL---RRQEGQQQLRQERDR 1619
Query: 942 KENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHK-QNLEIHRKIKQSEQELAYL 1000
K E+++L + L RQ +++ L + QL + Q L R K E+E
Sbjct: 1620 KFREDEQLLQEREEQQL--HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
Query: 1001 ERREREGKFKGRGNDRREKLQSFDSPERKR-----IKYSRETDSDRKLVDKEDIDTSSKG 1055
E E++ + + R RE+ Q ER+R + R + +RK ++E + ++
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 1056 GCVQQATGWRK 1066
+++ +RK
Sbjct: 1738 EQLRRQERYRK 1748
Score = 32.0 bits (71), Expect = 3.4
Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 27/239 (11%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E++E +E++ + + ++ KR+ +E++ R QE A E + A + K +P
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEER-----REQELAEEEQEQARERIKSRIPKW 704
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEE-----EEEQTPPPQPRTAQPQKREEQT 940
+ ES + + G E+EE E E + R + Q+ EEQ
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 941 KK-----ENEEDKLTDWNKLACL-----LCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKI 990
+ + EE +L+ RQ +E + Q+ ++ + R+
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Query: 991 KQSEQELAYLE------RREREGKFKGRGNDRREKLQSFDSPERKR-IKYSRETDSDRK 1042
++ E+EL +LE RRER + + + +E + S E++R K+ + + +RK
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/302 (21%), Positives = 122/302 (40%), Gaps = 29/302 (9%)
Query: 766 RGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLP 825
RG G W+S+ R S+S+ D + G Q EV +
Sbjct: 279 RGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGW---AGAQMEVDYTEQLNFS 335
Query: 826 EEEEI-----KEKKPTSQGKSSSKKEMSKRDGKE---KKDRGVTRFQENASE---GKAPA 874
+++E KE QG +S+ +K++ E K Q + ++ GK P+
Sbjct: 336 DDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395
Query: 875 EDVFKK-----PLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPR 929
+ + P PP + ++ PPP + P G G + +E+E + Q
Sbjct: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVP--GRPGPFPSKQQVADEDEIWKQRRRQQS 453
Query: 930 TAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNK-EVLIKHQQLSDLHKQNLEIHR 988
+ ++E EE ++ + K AC ++ K +L K ++ ++ E
Sbjct: 454 EISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE--- 510
Query: 989 KIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKED 1048
K ++ E+EL + +ERE K R D RE+ Q + K + RE + +RK +++
Sbjct: 511 KEREREKELEKEQEQERE---KEREKD-RERQQEKEKELEKEQEKQREMEKERKQEKEKE 566
Query: 1049 ID 1050
++
Sbjct: 567 LE 568
Score = 38.9 bits (89), Expect = 0.028
Identities = 43/235 (18%), Positives = 100/235 (42%), Gaps = 48/235 (20%)
Query: 819 PQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAED-- 876
P + +E+EI +++ Q + S+ E +++ +E+++R + ++ A K D
Sbjct: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERARKR-REEEERRMEEQRKAACAEKLKRLDEK 491
Query: 877 ---VFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQP 933
+ K+P P +++ E E + + E+E+E+E+ + +
Sbjct: 492 LGILEKQPSPEEIREREREK-------------EREREKELEKEQEQEREKEREKDRERQ 538
Query: 934 QKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQS 993
Q++E++ +KE E+ + + + K ++ +L +Q K+
Sbjct: 539 QEKEKELEKEQEKQREMEKER-----------------KQEKEKELERQ--------KEK 573
Query: 994 EQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKED 1048
E+EL ++ +E+E + + REKL+ P ++ E +KE+
Sbjct: 574 EKELQKMKEQEKECELE----KEREKLEEKIEPREPNLEPMVEKQESENSCNKEE 624
Score = 30.8 bits (68), Expect = 7.5
Identities = 37/194 (19%), Positives = 78/194 (40%), Gaps = 22/194 (11%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
EEEE + ++ + K + ++ G +K +E E + E +K
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENE 945
+KE + + + + E+E+E+++ + + + ++ E Q +KE E
Sbjct: 527 REKEREKDRER----------QQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE 576
Query: 946 EDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRER 1005
K+ + K L R+ K ++ + + NLE + ++SE +E
Sbjct: 577 LQKMKEQEKECELEKERE--------KLEEKIEPREPNLEPMVEKQESENSC----NKEE 624
Query: 1006 EGKFKGRGNDRREK 1019
E F + ++R EK
Sbjct: 625 EPVFTRQDSNRSEK 638
Score = 30.8 bits (68), Expect = 7.5
Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 8/74 (10%)
Query: 578 PQKTSIPAPLEKQP---NQPLRP--ADKEPEPRKREEGQESRLGHQKREAERYLPPSRRE 632
P+++ +P P + +P ++ P ADK P P+ + +R +++ R PP + +
Sbjct: 1377 PRQSEVPKPEDGEPPRRHEQFIPIAADKRP-PKFERKFDPARERPRRQRPTR--PPRQDK 1433
Query: 633 GPTFRRDRERESWS 646
P FRR RERE+ S
Sbjct: 1434 PPRFRRLREREAAS 1447
>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
[Homo sapiens]
Length = 807
Score = 51.2 bits (121), Expect = 5e-06
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 37/204 (18%)
Query: 814 QEVYVPQDPGLPEEEEIKEKKPTSQGKSSS-KKEMSKRDGKEKKDRGVTRFQENASEGKA 872
+E+ V EE+ +KEK+ Q + KK+ R G+ KKD ++ E K
Sbjct: 43 EELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKD------VDDDGEEKE 96
Query: 873 PAEDVFKKPLPPTVKKEESPPPP-------KVVNPLIGLLGEYGGDSDYEEEEEEEQTPP 925
E + K +P + +++E P P K N L+ D EEEEEE+ P
Sbjct: 97 LMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALI------QDQSEEEEEEEKHP 150
Query: 926 PQP-------------RTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIK 972
P+P QP + ++ K+E + K NK A L + +E++ +
Sbjct: 151 PKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKE 210
Query: 973 HQQLSDLHKQNLEIHRKIKQSEQE 996
+ KQ E +K +Q E E
Sbjct: 211 KEP----PKQGKEKAKKAEQMEYE 230
Score = 36.2 bits (82), Expect = 0.18
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E++E K K+ + GKS+ + E ++ +K + R +N E A ++ K+P T
Sbjct: 514 EKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRR--KNQDEESQEAPELLKRPKEYT 571
Query: 886 VKKEESPPPPKVVNPLIGLLG 906
V + P PP + P++GL G
Sbjct: 572 V-RFTFPDPPPLSPPVLGLHG 591
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 49.3 bits (116), Expect = 2e-05
Identities = 90/415 (21%), Positives = 135/415 (32%), Gaps = 64/415 (15%)
Query: 12 GPFRGSQEERFA--------PGWNR---DYPP------------------PPLKSHAQER 42
GP RG +E+RF+ P W D PP PP + ++R
Sbjct: 967 GPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDR 1026
Query: 43 HSGNFPGRDSLPF-DFQGHSGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFS 101
S D P GP ++ S+ D G RG + RG D
Sbjct: 1027 GSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDD 1086
Query: 102 SSDFQSRDSSQLDFRGRDIHSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDAH 161
+ D + RG D G R + +R D + RG E +R+ D
Sbjct: 1087 RGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDD 1146
Query: 162 AVDFR---------GRDAPPSDFRGRGTYDLDFRGRDGSHADFRGRDLSDLDFRAREQSR 212
+ R G D+ P +R +R ++ + + G RE R
Sbjct: 1147 RLSRRADDDRFPRRGDDSRPGPWRPL-VKPGGWREKEKAREESWGPPRESRPSEEREWDR 1205
Query: 213 SDFRNRDVSDLDFRDKDGTQVDFRGRGSGTTDLDFRD-----------------RDTPHS 255
R+RD D + DKD + R R D R RD+
Sbjct: 1206 EKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRR 1265
Query: 256 DFRGRHRSRTDQDFRG--REMGSCMEFKDREMPPVDPNILDYIQPSTQDREHSGMNVNRR 313
D R R R ++D R RE + +DR PP + + + R +R
Sbjct: 1266 DDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPP----LRSEREEVSSWRRADDRKDDRV 1321
Query: 314 EESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFEHESPADFQNSQSPVQDQD 368
EE + PA + E + REGE + ++ E + D+D
Sbjct: 1322 EERDPPRRVPPPALSRDR-ERDRDREREGEKEKASWRAEKDRESLRRTKNETDED 1375
Score = 34.7 bits (78), Expect = 0.52
Identities = 27/133 (20%), Positives = 57/133 (42%), Gaps = 24/133 (18%)
Query: 827 EEEIKEKKPTSQG--------KSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVF 878
+ E + ++P +G +SSS ++ S+RD +++ DR R + D
Sbjct: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
Query: 879 KKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPP---PQPRTAQPQK 935
+ PP + E + + D +++ EE+ PP P P ++ ++
Sbjct: 1294 DRRGPPLRSEREE-------------VSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
Query: 936 REEQTKKENEEDK 948
R+ ++E E++K
Sbjct: 1341 RDRDREREGEKEK 1353
Score = 34.3 bits (77), Expect = 0.68
Identities = 40/188 (21%), Positives = 76/188 (40%), Gaps = 37/188 (19%)
Query: 911 DSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCR--------- 961
D D E++EEE+ T +RE+ + +N ++ + L + +
Sbjct: 721 DMDLWEQQEEERI------TTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEE 774
Query: 962 --RQFPNKEVLIKHQQLSDLHKQNLE-----IHRKIKQSEQ----ELAYLERREREGKFK 1010
+QF + +H +L + +Q E +R+ ++ EQ E ER ERE +
Sbjct: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
Query: 1011 GRGNDR----REKLQSFDSPERKR-------IKYSRETDSDRKLVDKEDIDTSSKGGCVQ 1059
+ + +E+++ + ERK+ + R + +R+L D S+ G
Sbjct: 835 AKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRD 894
Query: 1060 QATGWRKG 1067
WRKG
Sbjct: 895 SEGTWRKG 902
Score = 33.9 bits (76), Expect = 0.89
Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 25/127 (19%)
Query: 914 YEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKH 973
Y E+EEEEQ ++ EEQ KE EE + + K +E L ++
Sbjct: 807 YREKEEEEQ-----------RRAEEQMLKEREERERAERAK-----------REEELREY 844
Query: 974 QQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKY 1033
Q+ K+ E+ RK +Q E E+ ERR E + G + R+ + D +
Sbjct: 845 QERV---KKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRK 901
Query: 1034 SRETDSD 1040
E DS+
Sbjct: 902 GPEADSE 908
Score = 30.4 bits (67), Expect = 9.8
Identities = 52/187 (27%), Positives = 66/187 (35%), Gaps = 21/187 (11%)
Query: 96 RGGDFSSSDFQSRDSSQLDFRG--RDIHSGDFRDREGPP-MDYRGGDGTSMDY---RGRE 149
R GD S S SR + D G R D R GPP ++R G+G D R E
Sbjct: 877 RLGDSSLSRKDSRWGDR-DSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEE 935
Query: 150 APHMNYRDRDAHA--------VDFRGRDAPPSDFRGRGTYDLDFRGRDGSHADFRGRDLS 201
P D D V RG D RG RG D +R D
Sbjct: 936 RPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDD 995
Query: 202 DLDFRAREQSRSDFRNRDVSDLDFRDKDGTQVDFRGRGSGTTDLDFRDRDTPHSDFRGRH 261
R ++ R ++R+ +D D + G D RGS T + R D RG
Sbjct: 996 RPPRRIADEDRGNWRH---ADDDRPPRRGLDED---RGSWRTADEDRGPRRGMDDDRGPR 1049
Query: 262 RSRTDQD 268
R D +
Sbjct: 1050 RGGADDE 1056
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 48.9 bits (115), Expect = 3e-05
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 13/144 (9%)
Query: 814 QEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDG-----KEKKDRGVTRFQENAS 868
QEV V + P EEE+ T + K S K+E K++ +EKK+ V + +E+
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Query: 869 EG-KAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQ 927
E K AED K P P ++E+P +V + ++ + +E + P +
Sbjct: 891 EAKKEEAEDKKKVPTP----EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE 946
Query: 928 PRTAQPQK---REEQTKKENEEDK 948
+ A P+K +EE+ KK E+ K
Sbjct: 947 KKEAAPEKKDTKEEKAKKPEEKPK 970
Score = 42.0 bits (97), Expect = 0.003
Identities = 66/279 (23%), Positives = 111/279 (39%), Gaps = 48/279 (17%)
Query: 818 VPQDPGLPEEEE--IKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAE 875
V ++ PE+ + +KE+ T + S KE +K K K + E K PA+
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 876 DVFKKP---LPPTVK---KEESPPPPKVVNPL--------IGLLGEYGGDSDYEEEEE-- 919
+ + P P K KEE P K +PL + + S +EEE+
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 920 -----------EEQTPPPQPRTAQPQ--KREEQTKKENEEDKLTDWNKLACLLCRRQFPN 966
EE+ P P+T + + K+EE KKE + K+ + + A +
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV----EKPKE 887
Query: 967 KEVLIKHQQLSDLHK---------QNLEIHRKIKQSEQ-ELAYLERREREGKFKGRGNDR 1016
+V K ++ D K +E+ K E+ E+A E + + K + ++
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 1017 REKL-QSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSK 1054
+E + D+ E K K + ++ K KED T SK
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKA--KEDDKTLSK 984
Score = 36.6 bits (83), Expect = 0.14
Identities = 47/233 (20%), Positives = 95/233 (40%), Gaps = 27/233 (11%)
Query: 814 QEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENAS---EG 870
+E V ++ EE+E KE+ +GK E + +G E++ + +E AS E
Sbjct: 462 EETQVTEEVTEEEEKEAKEE----EGKEEEGGEEEEAEGGEEETKSPPA-EEAASPEKEA 516
Query: 871 KAPAEDVFKKPL-PPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPR 929
K+P ++ K P + +KEE+ P +V +P + +EE PP+ +
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP-----------EKAKSPAKEEAKSPPEAK 565
Query: 930 TAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRK 989
+ + ++ + + ++ E + + A + P K + + K E
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK----AKSPVKEEAKSPAEAKSP 621
Query: 990 IKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRK 1042
+K+ + A ++ E K K + + + SPE++ K + S K
Sbjct: 622 VKEEAKSPAEVKSPE---KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Score = 33.5 bits (75), Expect = 1.2
Identities = 36/146 (24%), Positives = 57/146 (39%), Gaps = 28/146 (19%)
Query: 813 QQEVYVPQDPGLPEEEEIK---EKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENAS- 868
++E P + PE+EE K E K + KS +K+E + ++ + +E A
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 869 ----------EGKAPAE-DVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEE 917
E K+PAE +K PT KEE+ P K +P E +
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPT--KEEAKSPEKAKSP-----------EKEEAK 661
Query: 918 EEEEQTPPPQPRTAQPQKREEQTKKE 943
E+ P + P+K + K E
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAE 687
Score = 32.7 bits (73), Expect = 2.0
Identities = 61/350 (17%), Positives = 124/350 (35%), Gaps = 57/350 (16%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKA 872
++E P + PE+ + K+ + + E + EK V ++ + K+
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 873 PAEDVFKKP------------LPPTVK---KEESPPPPKVVNPL--IGLLGEYGGDSDYE 915
P + K P P K KEE+ P K +P+ E E
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 916 EEEEEEQTPPPQ---------PRTAQPQKRE---------EQTKKENEEDKLTDWNKLAC 957
E + E+ P+ P P K E E+ K +E+ + +
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP 802
Query: 958 LLCRRQFPNKEVLIKHQQLSDLHK----QNLEIHRKIKQSEQELAYL----------ERR 1003
L + P KE+ K + S + + Q +++ K++E+E A ++
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862
Query: 1004 EREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATG 1063
E K + +K + + P+ +++ +E D+K V + + +K + A
Sbjct: 863 EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP 922
Query: 1064 WRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYRDAVRR 1113
K +A E + + + PS A + + + +T + ++
Sbjct: 923 KEK--------TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Score = 32.0 bits (71), Expect = 3.4
Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 22/139 (15%)
Query: 813 QQEVYVPQDPGLPEEEEIK---EKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE 869
++E P + PE+EE K E K + KS +K+E + ++ E
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK---------EE 571
Query: 870 GKAPAEDVFKKPLPPTVKKEESPP-----PPKVVNPLIGLLGEYGGDSDYEEEEEEEQTP 924
K+PAE + K+E P P K +P + E ++ + +EE
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP---VKEEAKSPAEAKSPVKEEAKS 628
Query: 925 PPQPRTAQPQKREEQTKKE 943
P + ++ P+K + TK+E
Sbjct: 629 PAEVKS--PEKAKSPTKEE 645
Score = 31.2 bits (69), Expect = 5.8
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 16/98 (16%)
Query: 815 EVYVPQDPGLPEEEEIKEKKPTSQ-----GKSSSKKEMS--KRDGKEKKDRGVTRFQENA 867
+V V +D E+ E+ +K+P K + KKE + K+D KE+K + +
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 868 SEGKAPAEDVFKKPLPPTVKKEE---------SPPPPK 896
++ K + + K+P P +K E S PP K
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 48.5 bits (114), Expect = 3e-05
Identities = 33/137 (24%), Positives = 70/137 (51%), Gaps = 10/137 (7%)
Query: 812 TQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGK 871
T++EV ++P P + E+ EK+ T ++K++ K++ K K + + E +
Sbjct: 603 TEKEVPSKEEPS-PVKAEVAEKQATDVKPKAAKEKTVKKETKVKPE-------DKKEEKE 654
Query: 872 APAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTA 931
P ++V KK +KKEE P +V + + + + ++E +++TPP + +
Sbjct: 655 KPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK--EEKKEPKKEVKKETPPKEVKKE 712
Query: 932 QPQKREEQTKKENEEDK 948
++ +++ KKE +E K
Sbjct: 713 VKKEEKKEVKKEEKEPK 729
Score = 33.9 bits (76), Expect = 0.89
Identities = 48/251 (19%), Positives = 95/251 (37%), Gaps = 47/251 (18%)
Query: 819 PQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVF 878
PQ + +EE++KE +P ++E++K E D G+T +EG+ E
Sbjct: 856 PQLELIEDEEKLKETEPVEAYVIQKEREVTKGPA-ESPDEGIT-----TTEGEGECEQT- 908
Query: 879 KKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREE 938
P+ + P+ E G D E+ E+E T EE
Sbjct: 909 ----------------PEELEPV-----EKQGVDDIEKFEDEGAGFEESSETGD---YEE 944
Query: 939 QTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELA 998
+ + E E+ D + C+ KH D E I++ + +A
Sbjct: 945 KAETEEAEEPEEDGEEHVCVSAS----------KHSPTEDEESAKAEADAYIREKRESVA 994
Query: 999 YLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKED-----IDTSS 1053
+ R E + E+ + ++ E + + +RE + + + ++ ED +D ++
Sbjct: 995 SGDDRAEEDMDEAIEKGEAEQSEE-EADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAA 1053
Query: 1054 KGGCVQQATGW 1064
+ G ++ G+
Sbjct: 1054 EAGGAEEQYGF 1064
Score = 32.3 bits (72), Expect = 2.6
Identities = 32/150 (21%), Positives = 61/150 (40%), Gaps = 28/150 (18%)
Query: 809 DPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENAS 868
+ ++E V + E+E+ K++ + K+ KKE + + KK+ + +
Sbjct: 635 EKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKE---VKKEIKKE 691
Query: 869 EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQP 928
E K P ++V K+ P VKKE K V + E ++E ++ P
Sbjct: 692 EKKEPKKEVKKETPPKEVKKEVKKEEKKEVK-----------KEEKEPKKEIKKLPKDAK 740
Query: 929 RTAQP--------------QKREEQTKKEN 944
+++ P K+EE KK++
Sbjct: 741 KSSTPLSEAKKPAALKPKVPKKEESVKKDS 770
Score = 32.0 bits (71), Expect = 3.4
Identities = 58/292 (19%), Positives = 122/292 (41%), Gaps = 40/292 (13%)
Query: 812 TQQEVYVPQDPGLPEEEEIKEKKPTSQG-KSSSKKEMSKRDGKEKKDRG--VTRFQENAS 868
TQ+++ + ++ ++K++ + + K ++K SK KE K+ VT+
Sbjct: 517 TQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEK 576
Query: 869 EGKAPAED--VFKKPLP------PTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEE 920
K +++ + KK P P+V ++E P + +P+ + E +D + + +
Sbjct: 577 PPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEP-SPVKAEVAEKQA-TDVKPKAAK 634
Query: 921 EQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVL-------IKH 973
E+T + + K+EE+ K + E K D + + + P KE + IK
Sbjct: 635 EKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIK----KEEKPKKEEVKKEVKKEIKK 690
Query: 974 QQLSDLHKQ------NLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREK---LQSFD 1024
++ + K+ E+ +++K+ E++ E +E + + K D ++ L
Sbjct: 691 EEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAK 750
Query: 1025 SPERKRIKYSRETDSDR-------KLVDKEDIDTSSKGGCVQQATGWRKGTG 1069
P + K ++ +S + K +K I K G +A GTG
Sbjct: 751 KPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTG 802
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 47.8 bits (112), Expect = 6e-05
Identities = 71/282 (25%), Positives = 110/282 (39%), Gaps = 33/282 (11%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTV 886
+EE + P +G+ SS++E GK +K V + + GKA V +K
Sbjct: 144 DEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKK----QAPGKA---SVSRKQAREES 196
Query: 887 KKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEE 946
++ E+ P + + G G S E E+E E+ Q + + ++ EE+ K+E+EE
Sbjct: 197 EESEAEPVQRTAKKVEG---NKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEE 253
Query: 947 DKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRERE 1006
DW RR+ +E KQ + R + S+ E E++E
Sbjct: 254 K--GDWKPRTRSNGRRKSAREERSC---------KQKSQAKRLLGDSDSE---EEQKEAA 299
Query: 1007 GKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRK 1066
G DR +Q S +R ++K + ED + S KG A G RK
Sbjct: 300 SSGDDSGRDREPPVQR-KSEDRTQLKGGKRLSG-----SSEDEEDSGKG--EPTAKGSRK 351
Query: 1067 GTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYR 1108
LG G S E E G G R S ++ R
Sbjct: 352 MARLG-STSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSR 392
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 47.4 bits (111), Expect = 8e-05
Identities = 54/244 (22%), Positives = 105/244 (43%), Gaps = 38/244 (15%)
Query: 828 EEIKEKKPTSQGKSSSKKEMSKRDGKEKKDR------GVTRFQENA------------SE 869
EE++ K+ + K+E K+ KE+K+R +T+ Q A ++
Sbjct: 370 EELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQ 429
Query: 870 G-KAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEE--EEEEQTPPP 926
G + P++D K P K+ P ++ + + E + E+ E+E+TPPP
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPP 489
Query: 927 QPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEI 986
+P++ E + E+ L DW +A + +V I+ ++ + ++ E
Sbjct: 490 ----VEPEEEE-----DTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE 540
Query: 987 HRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRI--KYSRETDSDRKLV 1044
+ ++SE+E E EG+ +G D ++ S + K + K S+E SD +
Sbjct: 541 EEEDEESEEE------EEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD 594
Query: 1045 DKED 1048
+D
Sbjct: 595 SDDD 598
Score = 37.0 bits (84), Expect = 0.11
Identities = 54/228 (23%), Positives = 91/228 (39%), Gaps = 39/228 (17%)
Query: 824 LPEEEEIKE-KKPTSQGKSSSKK-EMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKP 881
L E+EE++ KK S+ K S +K E K D GV E +E AED +
Sbjct: 253 LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312
Query: 882 LPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQ------- 934
KK++ GE +EE+E+E+ P T +
Sbjct: 313 KKKKDKKKKK--------------GE-------KEEKEKEKKKGPSKATVKAMQEALAKL 351
Query: 935 KREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSE 994
K EE+ +K EE+++ +L + KE Q+ + KQ E RK ++ +
Sbjct: 352 KEEEERQKREEEERIKRLEEL-------EAKRKEEERLEQEKRERKKQK-EKERK-ERLK 402
Query: 995 QELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRK 1042
+E L + +RE + + + + Q + P + + R D+K
Sbjct: 403 KEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKK 450
Score = 33.9 bits (76), Expect = 0.89
Identities = 58/247 (23%), Positives = 102/247 (41%), Gaps = 38/247 (15%)
Query: 831 KEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEG---KAPAEDVFKKPLPPTVK 887
KE++P + K KKE K+D E D + +E + E KA E V KP +
Sbjct: 33 KEQEP-QKSKGKKKKEKKKQDFDE--DDILKELEELSLEAQGIKADRETVAVKPTENNEE 89
Query: 888 KEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEED 947
+ S K G G+ D + EE E++ + +TA+P K E + ++++D
Sbjct: 90 EFTSKDKKKK-----GQKGKKQSFDDNDSEELEDKDSKSK-KTAKP-KVEMYSGSDDDDD 142
Query: 948 --KLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRER 1005
KL K +++ E + + S K+ I+ + ++ +L+ R
Sbjct: 143 FNKLPKKAKGKAQKSNKKWDGSE---EDEDNSKKIKERSRINSSGESGDESDEFLQ--SR 197
Query: 1006 EGKFKGRGNDRREKLQS------------------FDSPERKRIKYSRETDSDRKLVDKE 1047
+G+ K + N ++S + ER+R K E RKL +KE
Sbjct: 198 KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE 257
Query: 1048 DIDTSSK 1054
+++T K
Sbjct: 258 ELETGKK 264
Score = 30.8 bits (68), Expect = 7.5
Identities = 51/220 (23%), Positives = 90/220 (40%), Gaps = 28/220 (12%)
Query: 814 QEVYVPQDPGLPEE----EEIKEKKPTSQGKSSSKKE-MSKRDGKEKKDRGVTRFQENAS 868
Q V VP LP++ E+ K KK Q +S E M E ++GV +E
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 869 ----EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTP 924
E + ED EE+ KV + + + + + EEEEEEE+
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETE---KVEGNKVHIEVKENPEEE-EEEEEEEEED 544
Query: 925 PPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNL 984
+ + E ++ + E++K++D L ++ P+KE+ + SD
Sbjct: 545 EESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKK--PSKEMSSDSEYDSD------ 596
Query: 985 EIHRKIKQSEQELAY--LERREREGKFKGRGNDRREKLQS 1022
++++E AY +RR + + + N EKL++
Sbjct: 597 -----DDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRA 631
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 26/141 (18%)
Query: 60 HSGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFSSSDFQSRDSSQLDFRGRD 119
H GPP +V H GP P H+ RGG + L R
Sbjct: 351 HQGPPMHHVPGHESR-----GP---------PPHELRGGPLP-------EPRPLMAEPR- 388
Query: 120 IHSGDFRDREGPPMDYRGG-DGTSMDYRGREAPHMNYRDRDAHAVDFRGRDAPPSDFRGR 178
G D+ GPP+D RGG D +D RG EA M R DA ++ R +A + R
Sbjct: 389 ---GPMLDQRGPPLDGRGGRDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAM 445
Query: 179 GTYDLDFRGRDGSHADFRGRD 199
++ R + + RG D
Sbjct: 446 EARAMEARAMEVRGMEARGMD 466
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 46.2 bits (108), Expect = 2e-04
Identities = 60/248 (24%), Positives = 112/248 (45%), Gaps = 28/248 (11%)
Query: 809 DPNTQQEVYVPQDPGLPE-EEEIKEKK-------PTSQGKSSSKKEMSKRDGKEKK-DRG 859
+P ++E P+ P P+ +E KEKK P S KSS+KK S+ +KK ++G
Sbjct: 658 EPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKG 717
Query: 860 VTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEE 919
T EN+ K P P P +++E P K + Y D +++ +E
Sbjct: 718 KTEGSENSDLDKTP-------PPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDE 770
Query: 920 EEQTPPPQPRTAQPQ-KREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEV-----LIKH 973
E R + + EQ + + E + + + + +++ +EV +K+
Sbjct: 771 EADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEFYVKY 830
Query: 974 QQLSDLHKQ--NLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRI 1031
+ S LH Q ++E K K+ +Q++ + ++ + KF ++ ++L + D E RI
Sbjct: 831 KNFSYLHCQWASIEDLEKDKRIQQKIKRFKAKQGQNKFL---SEIEDELFNPDYVEVDRI 887
Query: 1032 -KYSRETD 1038
++R TD
Sbjct: 888 MDFARSTD 895
Score = 31.2 bits (69), Expect = 5.8
Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 7/141 (4%)
Query: 810 PNTQQEVYVPQDPGLPE-EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENAS 868
PN Q V D LP E++ ++KK + ++ SK GK+ GV + N +
Sbjct: 576 PNAQ---LVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRN 632
Query: 869 EGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQP 928
E+ KK K + P PK E +E++ +T P+P
Sbjct: 633 SLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKP 692
Query: 929 RTAQPQKREEQTKKENEEDKL 949
+++ K+ K ++E L
Sbjct: 693 KSS---KKSSNKKPDSEASAL 710
Score = 30.4 bits (67), Expect = 9.8
Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 16/129 (12%)
Query: 361 QSPVQDQDKSQLSGREEQSSDAGLFKEEGGLDFLGRQDTDYRSMEYRDVDHRLPGSQMFG 420
+ P K + G+EE+ G KE +Q+ + E V + L G ++
Sbjct: 2176 EEPENPAAKEKCEGKEEEEETDGSGKES-------KQECE---AEASSVKNELKGVEVGA 2225
Query: 421 YGQSKSFPEGKTARDAQRDLQDQDYRTGPSEEKPSRLIRLSGVPEDA------TKEEILN 474
SKS E + D + L+D D S+ + + R E++ ++E +
Sbjct: 2226 DTGSKSISEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKNFDEESNASMSTARDETRD 2285
Query: 475 AFRTPDGMP 483
F DG P
Sbjct: 2286 GFYMEDGDP 2294
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 46.2 bits (108), Expect = 2e-04
Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 24/129 (18%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E+E E K ++G+ E+ DG+ K + G T QE ++E A++ K
Sbjct: 795 EDENEAEGKGDNEGEDEG--EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGV---- 848
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKE-- 943
E+ G GGDS+ EEEEEEEQ + + ++ EE+ ++E
Sbjct: 849 ---EDGG-------------GSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKG 892
Query: 944 NEEDKLTDW 952
NEE DW
Sbjct: 893 NEEPLSLDW 901
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/252 (19%), Positives = 102/252 (40%), Gaps = 37/252 (14%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEG-KAPAEDVFKKPLP- 883
++E+ K P ++ KS+ ++E K +E+ + +EN G K P K P+P
Sbjct: 1338 KDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPR 1397
Query: 884 ---PTVKKEE---------SPPPPKVVNPLIGLLGEYGG-----------DSDYEEEEEE 920
P ++E+ SP V + L E E E ++
Sbjct: 1398 SDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDK 1457
Query: 921 EQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLH 980
+ + R+ + +K++E+ +KE + D + ++ L +R+ + + S+
Sbjct: 1458 KDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESP 1517
Query: 981 KQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSD 1040
++ + K K+ + + GK KG + + EK+ S +K ++ +E
Sbjct: 1518 CESPYPNEKDKEKNKS-------KSSGKEKGSDSFKSEKMDKISSGGKKESRHDKE---- 1566
Query: 1041 RKLVDKEDIDTS 1052
K+ KE D+S
Sbjct: 1567 -KIEKKEKRDSS 1577
Score = 33.1 bits (74), Expect = 1.5
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 3/112 (2%)
Query: 837 SQGKSSSK--KEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPP 894
+ G +S+K KE K GKEK+ + E + +D +KP K+E
Sbjct: 1257 NSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARE 1316
Query: 895 PKVVNPLIGLLGE-YGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENE 945
K P E + + ++E+ + P + ++ Q ++RE++ +E +
Sbjct: 1317 TKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERD 1368
>gi|4826972 RNA binding motif protein 8A [Homo sapiens]
Length = 174
Score = 45.4 bits (106), Expect = 3e-04
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 14/138 (10%)
Query: 387 EEGGLDFLGRQDTDYRSMEYRDVDHRLPGSQMFGYGQSKSFPEGKTAR---DAQRDLQDQ 443
E GG DF +D D + ++ + G G+G EG AR D QD
Sbjct: 9 EAGGEDFAMDEDGDESIHKLKEKAKKRKGR---GFGSE----EGSRARMREDYDSVEQDG 61
Query: 444 DYRTGPSEEKPSRLIRLSGVPEDATKEEILNAFRTPDGMPVKNLQLK-EYNTGYDYGYVC 502
D GP ++ ++GV E+AT+E+I + F + +KN+ L + TGY GY
Sbjct: 62 D-EPGPQRSVEGWILFVTGVHEEATEEDIHDKFA--EYGEIKNIHLNLDRRTGYLKGYTL 118
Query: 503 VEFSLLEDAIGCMEANQG 520
VE+ ++A ME G
Sbjct: 119 VEYETYKEAQAAMEGLNG 136
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/165 (24%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 295 YIQPSTQDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQGVAFEHESP 354
Y QP TQD+ +R+++S+H ER +G+ H + + QG H
Sbjct: 379 YGQPDTQDQSSHYGQTDRQDQSSHYGQTER------QGQSSHYSQMDRQGQG---SHYGQ 429
Query: 355 ADFQNSQSPVQDQDKSQLSG------REEQSSDAGLFKEEGGLDFLGRQDTDYRSMEYRD 408
D Q S D+ + R+ QSS G +G + D +S Y
Sbjct: 430 TDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGK 489
Query: 409 VDHRLPGSQMFGYGQSKSFPEGKTARDAQRDLQDQDYRTGPSEEK 453
+D + Q + YGQ +G+++ Q D Q Q + G + +
Sbjct: 490 IDRQ---DQSYHYGQPDG--QGQSSHYGQTDRQGQSFHYGQPDRQ 529
>gi|70608155 phosphodiesterase 3A [Homo sapiens]
Length = 1141
Score = 45.1 bits (105), Expect = 4e-04
Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 16/108 (14%)
Query: 910 GDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDW--NKLACLLCRRQFPN- 966
GD+D EEEEEE P EE+T + NE K + K+ C + + N
Sbjct: 1034 GDTDDPEEEEEEAPAP----------NEEETCENNESPKKKTFKRRKIYCQITQHLLQNH 1083
Query: 967 ---KEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKG 1011
K+V+ + Q+L+ + Q+L+ + SEQ A E E +GK +G
Sbjct: 1084 KMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQAIKEEEEEKGKPRG 1131
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 45.1 bits (105), Expect = 4e-04
Identities = 51/227 (22%), Positives = 95/227 (41%), Gaps = 33/227 (14%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTV 886
+ EI+E++ + + KKE KE+++R R +E E K + KK
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERRERE-KRKREREKERK---RERGKKEKKGER 90
Query: 887 KKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEE 946
KKEE + E+E ++ + R + +K +T KE +E
Sbjct: 91 KKEERERKKR------------------RREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 947 DKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRK-IKQSEQELAYLERRER 1005
+ + K R + +E + ++ K+ + RK + + E+E ER+ER
Sbjct: 133 RERKEERK------REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 1006 EGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTS 1052
K R +R+E+ + + ER+ K R+ +RK ++D T+
Sbjct: 187 ----KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Score = 45.1 bits (105), Expect = 4e-04
Identities = 48/217 (22%), Positives = 98/217 (45%), Gaps = 14/217 (6%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTV 886
E EI+ +K + + S +K+ + K K++R R +E + K ++
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 887 KKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTK-KENE 945
+++E+ + E G S +E E ++ + R + +K+EE+ K +E +
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 946 EDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRER 1005
E K + R+Q KE K ++ + K+ E +RK ++ E+E ERRER
Sbjct: 162 ERKKRE---------RKQVGEKEEERKEKERKERKKR--ERNRKERKKERERK--ERRER 208
Query: 1006 EGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRK 1042
+ + K + ++E+ + + R++ + RE +K
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 44.3 bits (103), Expect = 7e-04
Identities = 48/212 (22%), Positives = 90/212 (42%), Gaps = 27/212 (12%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E E KE++ + K +KE + GK++K + + + + E+ +
Sbjct: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTK-KEN 944
KKE+ E G S +E E ++ + R + +K+EE+ K +E
Sbjct: 116 KKKEKK---------------ERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 945 EEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRE 1004
+E K + R+Q KE K ++ + K+ E +RK ++ E+E R+
Sbjct: 161 KERKKRE---------RKQVGEKEEERKEKERKERKKR--ERNRKERKKERERKERRERK 209
Query: 1005 REGKFKGRGNDRREKLQSFDSPERKRIKYSRE 1036
+E K K R+K + + E++R K R+
Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGKRERK 241
Score = 31.6 bits (70), Expect = 4.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 592 NQPLRPADKEPEPRKREEGQESRL-GHQKREAERYLPPSRREGPTFRRDRERESWSGETR 650
++P + E R+RE E+R G ++RE+ER RE R++ER+ G+
Sbjct: 26 SKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE 85
Query: 651 QDGESK 656
+ GE K
Sbjct: 86 KKGERK 91
Score = 30.4 bits (67), Expect = 9.8
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 18/109 (16%)
Query: 555 SCSFCKNP-------REVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKR 607
SCS P E+ E ++E+ T + +K E++ + + +E E RKR
Sbjct: 21 SCSHISKPCTQPGWQSEIREREREIETRKEGKK-------ERESER--KKERREREKRKR 71
Query: 608 EEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESK 656
E +E + K+E + RE +R RE+E+ GE ++ + K
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERK--KRRREKENKEGEEKEKRKKK 118
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 45.1 bits (105), Expect = 4e-04
Identities = 45/233 (19%), Positives = 110/233 (47%), Gaps = 21/233 (9%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENA---SE 869
+QE V + G E+E + ++ Q + + ++ +++G+ ++ G R QE E
Sbjct: 105 EQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQE 163
Query: 870 GKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPR 929
G+ ++ + V+++E V G +GE G +EE+ EQ Q +
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQ-----VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Query: 930 TAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRK 989
Q ++EEQ +K +E+++ + + + Q ++V + +Q+ +Q E +
Sbjct: 219 EEQMGEQEEQMRK--QEEQMGEQEE------QVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 990 IKQSEQEL----AYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETD 1038
+++ E+++ E+ E+ G+ + + ++ E+++ + R++ + RE +
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/208 (19%), Positives = 95/208 (45%), Gaps = 33/208 (15%)
Query: 813 QQEVYVPQDPGLPEEEE--IKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEG 870
Q+E Q+ + E+EE +K+K+ T Q + + ++E R+ +E+ + +E +
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 871 KAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRT 930
+ E + K+ +KE+ + E +EE+ EQ Q +
Sbjct: 320 REQEEQMGKQEEQMWEQKEQ--------------MWEQKEQMWKQEEQMGEQEEQMQKQE 365
Query: 931 AQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKI 990
Q +K+EEQ +K+ E+ R+Q +++ + +Q+ + +Q E ++
Sbjct: 366 EQVRKQEEQMRKQEEQ-------------MRKQ--EEQMRKQEEQMGEQKEQMGEQKEQM 410
Query: 991 KQSEQELAYLERREREGKFKGRGNDRRE 1018
++ E+++ E++E+ K + +++E
Sbjct: 411 REQEEQMG--EQKEQMRKQEEHMGEQKE 436
Score = 32.7 bits (73), Expect = 2.0
Identities = 49/254 (19%), Positives = 110/254 (43%), Gaps = 27/254 (10%)
Query: 813 QQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENA---SE 869
+QE V + G E+E + ++ Q + + ++ +++G+ ++ G R QE E
Sbjct: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQE 114
Query: 870 GKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPR 929
G+ ++ + V+++E V G + E G +E + EQ Q R
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQ-----VREQEGQVREQEGQVREQEGQVREQEG--QVR 167
Query: 930 TAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRK 989
+ Q RE++ + +E ++ + Q +E + Q+ + +Q ++ ++
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEG--------QMGEQEGQMGEQE-EQMGEQEEQMQKQ 218
Query: 990 IKQ-SEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETD------SDRK 1042
+Q EQE ++ E+ G+ + + + E++Q + RK+ + RE + ++
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 1043 LVDKEDIDTSSKGG 1056
L KE + + G
Sbjct: 279 LKQKEQTEQEEQTG 292
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 43.9 bits (102), Expect = 9e-04
Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 42/214 (19%)
Query: 834 KPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPP 893
KP +Q +S KKE +R+ K K++R R +E + K KK +
Sbjct: 27 KPCTQRESERKKERRERE-KRKREREKERKRERGKKEK---------------KKRKKR- 69
Query: 894 PPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWN 953
E G + + + +E E+Q + + + +K+E++ ++ + +
Sbjct: 70 -------------ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR----- 111
Query: 954 KLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRG 1013
R + KE + ++ ++ + RK K+ ++ ER +RE K K R
Sbjct: 112 -------RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK 164
Query: 1014 NDRREKLQSFDSPERKRIKYSRETDSDRKLVDKE 1047
+ REK + + ERK+ + +E +K KE
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKE 198
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 29/214 (13%)
Query: 826 EEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPT 885
E E KE++ + K +KE + GK++K + R + E K + +K
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 886 VKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENE 945
+++ K G E E E +Q + + + +KR ++ K+E E
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 946 EDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRER 1005
K +E K ++ + K+ E +RK ++ E+E R+ER
Sbjct: 153 RGK------------------RERKRKKRKKEEREKKR-ERNRKERKKERE-----RKER 188
Query: 1006 EGKFKGRGNDRREKLQSFDSPERKRIKYSRETDS 1039
+ K R +RR+K + +K K R+TDS
Sbjct: 189 RERKKERKKERRKKKE-----RKKDRKTDRQTDS 217
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapiens]
Length = 820
Score = 43.9 bits (102), Expect = 9e-04
Identities = 57/245 (23%), Positives = 102/245 (41%), Gaps = 30/245 (12%)
Query: 828 EEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVK 887
EE E KP K+ + E KR +E ++R R E + + +D+ +K L +
Sbjct: 154 EEEAEAKPKFLSKAEREAEALKRRQQEVEER--QRMLEEERKKRKQFQDLGRKMLEDPQE 211
Query: 888 KEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENE-- 945
+E ++ G E G EE+++ ++ + R K+ +T+ N+
Sbjct: 212 RERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRK 271
Query: 946 --------EDKLTDWNKL------ACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIK 991
ED D+N L LL R ++ + ++ S + +E R ++
Sbjct: 272 FVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLE 331
Query: 992 QSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDT 1051
+ EQE A L R+ R+ + K R +DR + D TD D ++ +ED
Sbjct: 332 EKEQEEARL-RKLRKKEAKQRWDDRHWSQKKLD----------EMTDRDWRIF-REDYSI 379
Query: 1052 SSKGG 1056
++KGG
Sbjct: 380 TTKGG 384
Score = 34.7 bits (78), Expect = 0.52
Identities = 67/309 (21%), Positives = 112/309 (36%), Gaps = 61/309 (19%)
Query: 834 KPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPP 893
K + + ++E K + KKDR + +G +D + L P K+
Sbjct: 66 KSAERERRHKERERDKERDRNKKDR------DRDKDGHRRDKDRKRSSLSPGRGKD---- 115
Query: 894 PPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDK----- 948
+ D + +++EE + AQP EE K+ E++
Sbjct: 116 --------------FKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKP 161
Query: 949 --LTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERRER- 1005
L+ + A L RRQ +E ++ KQ ++ RK+ + QE ERRER
Sbjct: 162 KFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERM 221
Query: 1006 ----------EGKFKGR-GNDRREKLQSFDSPERKRIKYSRETD--SDRKLVDKEDIDTS 1052
EG+ K R D+ ++L + IK R T +DRK V + D
Sbjct: 222 ERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDAS-- 279
Query: 1053 SKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYRDAVR 1112
+ T + Y +P + + RG G + KR+ + Y D +
Sbjct: 280 -------------EDTSIDY-NPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLME 325
Query: 1113 RVMFARYKE 1121
+ KE
Sbjct: 326 KRRTLEEKE 334
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 43.9 bits (102), Expect = 9e-04
Identities = 65/278 (23%), Positives = 103/278 (37%), Gaps = 27/278 (9%)
Query: 106 QSRDSSQLDFRGRDIHSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDAHAVDF 165
+SR+ S+ + R + R E P RG G+ +D + + NY D +
Sbjct: 546 ESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQID---SHSSNSNYHDSWETRSSY 602
Query: 166 RGRDAPPSDFRGRGTYDLDFRGRDGSHADFRGRDLSDLDFRAREQSRSDFRNRDVSDLDF 225
RD P D F R H + RD + D R R RN ++ +
Sbjct: 603 PERDRYPERDNRDQARDSSFERR---HGERDRRDNRERDQRPSSPIRHQGRNDELERDER 659
Query: 226 RDKDGTQVDFRGRGSGTTDLDFRDRDTPHSDFRGRHRSRTDQDFRGREMGSCMEFKDREM 285
R++ +VD R D R+RD R R R R + R RE K+RE
Sbjct: 660 REE--RRVD---RVDDRRDERARERDRERERDRERERERERERDRERE-------KERE- 706
Query: 286 PPVDPNILDYIQPSTQDREHSGMNVNRREESTHDHTIERPAFGIQKGEFEHSETREGETQ 345
L+ + ++RE +R + DH ER + E E RE +
Sbjct: 707 -------LERERAREREREREKER-DRERDRDRDHDRERERERERDREKEREREREERER 758
Query: 346 GVAFEHESPADFQNSQSPVQDQDKSQLSGREEQSSDAG 383
E E + + + +++DK + R+ + D G
Sbjct: 759 ERERERERERERERERERARERDKERERQRDWEDKDKG 796
Score = 33.5 bits (75), Expect = 1.2
Identities = 56/296 (18%), Positives = 112/296 (37%), Gaps = 48/296 (16%)
Query: 825 PEEEEIKEKKPTSQGKSSSKK----EMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKK 880
PE + E+ Q + SS + E +RD +E+ R + + + ++
Sbjct: 603 PERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDE---- 658
Query: 881 PLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQT 940
++EE + V+ + E + D E E + E+ ++RE +
Sbjct: 659 ------RREE-----RRVDRVDDRRDERARERDRERERDRERE----------RERERER 697
Query: 941 KKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYL 1000
+E E+++ + + +E + ++ D + H + ++ E+E
Sbjct: 698 DREREKERELERERA-----------REREREREKERDRERDRDRDHDRERERERERDRE 746
Query: 1001 ERREREGKFKGRGNDRREKLQSFDSPERKRIK---YSRETDSDRKLVDKEDIDTSSKGGC 1057
+ RERE + + R +R + + ER+R + RE D + DK D K
Sbjct: 747 KEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREE 806
Query: 1058 VQQATGWRKG-----TGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYR 1108
+++ R G + Y + G S ++ R R S + S NE +R
Sbjct: 807 IREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 862
Score = 32.7 bits (73), Expect = 2.0
Identities = 56/328 (17%), Positives = 123/328 (37%), Gaps = 45/328 (13%)
Query: 740 GKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNR----QGQQSSSDCYIYDSA 795
G+ R D+ D D RD R D+S DT + +S+ D + Y
Sbjct: 455 GRDRRDARDTRDRRELRDS----RDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510
Query: 796 TGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKE--------- 846
G D + +++ Y P++ ++E+ ++ ++ S+ E
Sbjct: 511 EGR----------DTHRKEDTY-PEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDR 559
Query: 847 MSKRDGK-----EKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPL 901
M + G+ EK RG Q ++ + D ++ +++ P
Sbjct: 560 MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETR-SSYPERDRYPERDNRDQAR 618
Query: 902 IGLLGEYGGDSDYEEEEEEEQTP--PPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLL 959
G+ D + E +Q P P + + + ++ ++E D++ D
Sbjct: 619 DSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDD-------- 670
Query: 960 CRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREK 1019
RR +E + ++ + ++ + ++ E+EL RERE + + + R++
Sbjct: 671 -RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729
Query: 1020 LQSFDSPERKRIKYSRETDSDRKLVDKE 1047
+ D + + RE + +R+ ++E
Sbjct: 730 DRDHDRERERERERDREKEREREREERE 757
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/234 (22%), Positives = 99/234 (42%), Gaps = 31/234 (13%)
Query: 824 LPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEK---KDRGVTRFQENASEGKAPAEDVFKK 880
+ E+E +KEK + + ++E K GK K K+R R ++ + + E +K
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 881 PLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQT 940
+KE+ + E + +E+ ++++ PR+ +R +
Sbjct: 444 DRDKEKEKEQDKEKER----------EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Query: 941 KKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYL 1000
+E + + R +K + K + +N +K K+ E+E ++
Sbjct: 494 SRERRRRRSRSSS-------RSPRTSKTIKRKSSRSPSPRSRN----KKDKKREKERDHI 542
Query: 1001 -ERREREGKFKGR--GNDR--REKLQSFDSPERKRIKYSRETDSD-RKLVDKED 1048
ERRERE R NDR +EKL+ +S K ++++E DS K VD +D
Sbjct: 543 SERRERERSTSMRKSSNDRDGKEKLEK-NSTSLKEKEHNKEPDSSVSKEVDDKD 595
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/234 (22%), Positives = 99/234 (42%), Gaps = 31/234 (13%)
Query: 824 LPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEK---KDRGVTRFQENASEGKAPAEDVFKK 880
+ E+E +KEK + + ++E K GK K K+R R ++ + + E +K
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 881 PLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQT 940
+KE+ + E + +E+ ++++ PR+ +R +
Sbjct: 328 DRDKEKEKEQDKEKER----------EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Query: 941 KKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYL 1000
+E + + R +K + K + +N +K K+ E+E ++
Sbjct: 378 SRERRRRRSRSSS-------RSPRTSKTIKRKSSRSPSPRSRN----KKDKKREKERDHI 426
Query: 1001 -ERREREGKFKGR--GNDR--REKLQSFDSPERKRIKYSRETDSD-RKLVDKED 1048
ERRERE R NDR +EKL+ +S K ++++E DS K VD +D
Sbjct: 427 SERRERERSTSMRKSSNDRDGKEKLEK-NSTSLKEKEHNKEPDSSVSKEVDDKD 479
>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
Length = 871
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 17/155 (10%)
Query: 805 GTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQG-----KSSSKKEMSKRDGKEKKDRG 859
GT D ++ + G P E KE+ G + ++ K+ K DGK+ ++
Sbjct: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
Query: 860 VTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEE 919
+ SEG E+ KKE+S K + ++ GD ++E
Sbjct: 320 SNDDKTKKSEGDGDKEE----------KKEDSEKEAKKSSKKRN--RKHSGDDSFDEGSV 367
Query: 920 EEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNK 954
E + A+ +K E + KE E+ K +W K
Sbjct: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402
Score = 30.8 bits (68), Expect = 7.5
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE-GKAPAEDVFKKPLPPT 885
++E K++ + K SSKK K G + D G E+ SE G+A E + L
Sbjct: 333 DKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEK 392
Query: 886 VK-KEESPPPPK 896
K KEE PK
Sbjct: 393 EKPKEEEWEKPK 404
>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
Length = 875
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 17/155 (10%)
Query: 805 GTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQG-----KSSSKKEMSKRDGKEKKDRG 859
GT D ++ + G P E KE+ G + ++ K+ K DGK+ ++
Sbjct: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
Query: 860 VTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEE 919
+ SEG E+ KKE+S K + ++ GD ++E
Sbjct: 320 SNDDKTKKSEGDGDKEE----------KKEDSEKEAKKSSKKRN--RKHSGDDSFDEGSV 367
Query: 920 EEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNK 954
E + A+ +K E + KE E+ K +W K
Sbjct: 368 SESESESESGQAEEEKEEAEALKEKEKPKEEEWEK 402
Score = 30.8 bits (68), Expect = 7.5
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 827 EEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASE-GKAPAEDVFKKPLPPT 885
++E K++ + K SSKK K G + D G E+ SE G+A E + L
Sbjct: 333 DKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEK 392
Query: 886 VK-KEESPPPPK 896
K KEE PK
Sbjct: 393 EKPKEEEWEKPK 404
>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
substrate 1 [Homo sapiens]
Length = 243
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 812 TQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGK 871
++Q + +D G EE+E +++ P + S S ++ D + D G ++ + K
Sbjct: 101 SKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLMEDDDDS-DYGSSKKKNKKMVKK 159
Query: 872 APAEDVFKKPLPPTVKKEESPPPPK----VVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQ 927
+ E KK P +K +P P K V P + S EE+EE E P +
Sbjct: 160 SKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKK 219
Query: 928 PRTAQPQKREEQTKKENE 945
T+ P ++ E+E
Sbjct: 220 TSTSPPPEKSGDEGSEDE 237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,920,727
Number of Sequences: 37866
Number of extensions: 3044189
Number of successful extensions: 20115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 674
Number of HSP's that attempted gapping in prelim test: 14698
Number of HSP's gapped (non-prelim): 4650
length of query: 1123
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1010
effective length of database: 13,968,660
effective search space: 14108346600
effective search space used: 14108346600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.