Search of human proteins with 5031795

Search of human proteins with 5031795

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
         (352 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]          716   0.0  
gi|13899338 activin beta E [Homo sapiens]                             248   4e-66
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]      218   6e-57
gi|4504699 inhibin beta A precursor [Homo sapiens]                    199   4e-51
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...   100   2e-21
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...    97   2e-20
gi|110349792 growth differentiation factor 1 [Homo sapiens]            93   3e-19
gi|61835232 growth differentiation factor 7 preproprotein [Homo ...    89   5e-18
gi|4885259 myostatin [Homo sapiens]                                    86   5e-17
gi|10190670 growth differentiation factor 3 precursor [Homo sapi...    86   5e-17
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]       84   2e-16
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]              84   2e-16
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...    83   4e-16
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...    83   4e-16
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...    83   4e-16
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...    82   6e-16
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa...    80   3e-15
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap...    80   4e-15
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...    79   5e-15
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...    75   7e-14
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa...    75   1e-13
gi|4826740 growth differentiation factor 10 precursor [Homo sapi...    70   2e-12
gi|4507465 transforming growth factor, beta 3 [Homo sapiens]           70   3e-12
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...    69   5e-12
gi|222352098 nodal precursor [Homo sapiens]                            69   6e-12
gi|63025222 transforming growth factor, beta 1 [Homo sapiens]          69   8e-12
gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo ...    66   4e-11
gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo sa...    66   4e-11
gi|7705308 growth differentiation factor 2 [Homo sapiens]              61   1e-09
gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]      60   4e-09

>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score =  716 bits (1849), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR 60
           MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR
Sbjct: 1   MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR 60

Query: 61  PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSS 120
           PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSS
Sbjct: 61  PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSS 120

Query: 121 DRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQL 180
           DRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQL
Sbjct: 121 DRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQL 180

Query: 181 PLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDC 240
           PLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDC
Sbjct: 181 PLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDC 240

Query: 241 QGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLN 300
           QGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLN
Sbjct: 241 QGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLN 300

Query: 301 LLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
           LLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
Sbjct: 301 LLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352


>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score =  248 bits (634), Expect = 4e-66
 Identities = 154/357 (43%), Positives = 206/357 (57%), Gaps = 28/357 (7%)

Query: 9   FLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVS 68
           +L+L    V     G  CP+CGG  L  +++R L+L+LAK+ ILD LHLT RP +  P  
Sbjct: 9   WLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSRPRITHPPP 68

Query: 69  RAALRTALQHLHGVPQGALLEDNREQECEIISFAE-TGLSTINQTRLDFHFSSDRTAGDR 127
           +AAL  AL+ L     G++   N E   E+ISFA  T  ++   + L FH S+ R+    
Sbjct: 69  QAALTRALRRLQ---PGSVAPGNGE---EVISFATVTDSTSAYSSLLTFHLSTPRS---H 119

Query: 128 EVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNT---NLTLATQYLLEVDASGWHQLPLGP 184
            +  A L   V LP+    TL +R+   GP      + TL  ++   +   GWH L L  
Sbjct: 120 HLYHARLWLHV-LPT-LPGTLCLRIFRWGPRRRRQGSRTLLAEH--HITNLGWHTLTLPS 175

Query: 185 EAQAACSQGHLTLEL---VLEGQ---VAQSSVILGGAAHR-PFVAARVRVG--GKHQIHR 235
                   G L L+L    LEG      Q   +L  A H+ PF+  ++R    G  +  R
Sbjct: 176 SGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARR 235

Query: 236 RGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFH 295
           R   C+  + +CCR++ +VDF+E+GW DWI+QPEGY +N+C GQCP H+AG PGIAASFH
Sbjct: 236 RTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFH 295

Query: 296 TAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
           +AV +LLKAN         SCCVPTARRPLSLLY D + N+VKTD+PDMVVEACGCS
Sbjct: 296 SAVFSLLKANNP--WPASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 350


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score =  218 bits (555), Expect = 6e-57
 Identities = 139/385 (36%), Positives = 202/385 (52%), Gaps = 51/385 (13%)

Query: 13  APTTVATPRA----------GGQ---CPACGG--PTLELESQRELLLDLAKRSILDKLHL 57
           +PT   TP A          GG    C +CGG     EL       L+  KR IL +L +
Sbjct: 29  SPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQM 88

Query: 58  TQRPTLNRPVSRAALRTALQHLHGVPQGALLEDNR-----------------EQECEIIS 100
             RP +   V +AA+ TAL+ LH    G + ED R                 E+  EIIS
Sbjct: 89  RGRPNITHAVPKAAMVTALRKLHA---GKVREDGRVEIPHLDGHASPGADGQERVSEIIS 145

Query: 101 FAETGLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-----PSNTTWTLKVRVLVL 155
           FAET     ++ RL F  S++    +  V QASL  +++L        +   ++V+V   
Sbjct: 146 FAETDGLASSRVRLYFFISNEGNQ-NLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQ 204

Query: 156 GPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSVIL--- 212
              + +     +  +++  SGWH  PL    QA   +G   L L ++    Q   ++   
Sbjct: 205 EQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVF 264

Query: 213 ---GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQP 268
              G  +HRPFV  + R+G  +H+I +RG++C G + +CCRQ+FF+DFR IGW+DWII P
Sbjct: 265 VDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAP 324

Query: 269 EGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLK-ANTAAGTTGGGSCCVPTARRPLSL 327
            GY  N+C G CP ++AG+PG A+SFHTAV+N  +      GT    SCC+PT    +S+
Sbjct: 325 TGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTV--NSCCIPTKLSTMSM 382

Query: 328 LYYDRDSNIVKTDIPDMVVEACGCS 352
           LY+D + NIVK D+P+M+VE CGC+
Sbjct: 383 LYFDDEYNIVKRDVPNMIVEECGCA 407


>gi|4504699 inhibin beta A precursor [Homo sapiens]
          Length = 426

 Score =  199 bits (505), Expect = 4e-51
 Identities = 126/401 (31%), Positives = 197/401 (49%), Gaps = 75/401 (18%)

Query: 22  AGGQCPACGGPTL--ELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHL 79
           A   CP+C    L  ++ + +  +++  K+ IL+ LHL +RP + +PV +AAL  A++ L
Sbjct: 31  AAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKL 90

Query: 80  H--------------GVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSSDRTAG 125
           H               + + A + +  EQ  EII+FAE+G +     R   HF   +   
Sbjct: 91  HVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA-----RKTLHFEISKEGS 145

Query: 126 DREV-QQASLMFFVQLPSNTTWTLKVRVLVL-------GPHNT-------------NLTL 164
           D  V ++A +  F+++P       KV + +        G  +T             +  L
Sbjct: 146 DLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELL 205

Query: 165 ATQYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSS----VILG------- 213
            ++ +++   S WH  P+    Q    QG  +L++ +  +  Q S    V+LG       
Sbjct: 206 LSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEE 265

Query: 214 --------------GA------AHRPFVAARVRVGGKH--QIHRRGIDCQGGSRMCCRQE 251
                         GA      +HRPF+  + R    H  +  RRG++C G   +CC+++
Sbjct: 266 EGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQ 325

Query: 252 FFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTT 311
           FFV F++IGW+DWII P GY  N+C G+CP HIAG  G + SFH+ V+N  +    +   
Sbjct: 326 FFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFA 385

Query: 312 GGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
              SCCVPT  RP+S+LYYD   NI+K DI +M+VE CGCS
Sbjct: 386 NLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 426


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score =  100 bits (250), Expect = 2e-21
 Identities = 99/375 (26%), Positives = 148/375 (39%), Gaps = 54/375 (14%)

Query: 14  PTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALR 73
           P     P   G CP C    +  +  REL L+  K  IL KL L + P ++R V +  L 
Sbjct: 51  PAPSVAPEPDG-CPVC----VWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLP 105

Query: 74  TA-----LQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTR---------LDFHFS 119
            A     +  LH     AL  ++  +E E  +  ET +S   +T          L  HF 
Sbjct: 106 KAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFH 165

Query: 120 SDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTL-------------AT 166
                   +V +A L  +++ P     T+ +++L L P     T              + 
Sbjct: 166 FSPKVMFTKVLKAQLWVYLR-PVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSL 224

Query: 167 QYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEG------QVAQSSVILGGAAHRPF 220
           +  L   +  W  +       +   Q      + +         +A +S+  G     PF
Sbjct: 225 KIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPF 284

Query: 221 VAARVRVGGKHQIHRRGIDCQGGSR--MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIG 278
           +  RV    K      G+DC   S    CCR    VDF   GW DWII P+ Y  N+C G
Sbjct: 285 MELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSG 343

Query: 279 QCP-LHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIV 337
           QC  + +   P      HT ++       +AG      CC PT   P+++LY++    I+
Sbjct: 344 QCEYMFMQKYP------HTHLVQQANPRGSAGP-----CCTPTKMSPINMLYFNDKQQII 392

Query: 338 KTDIPDMVVEACGCS 352
              IP MVV+ CGCS
Sbjct: 393 YGKIPGMVVDRCGCS 407


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 95/391 (24%), Positives = 155/391 (39%), Gaps = 48/391 (12%)

Query: 4   SLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTL 63
           +LLL  +LL       P  G +  A            + +L   +  +L    L QRPT 
Sbjct: 10  ALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTP 69

Query: 64  NRPVSRAALRTALQHLHGVPQGALLEDNREQECE-----IISF-----AETGLSTINQTR 113
           +R          L   H    G+   D+R +        + SF      E    T  +T 
Sbjct: 70  SRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTT 129

Query: 114 LDFHFSSDRTAGDREVQQASLMFFVQ-----LPSNTTWTLKVRVL-VLGPHNTNLTLATQ 167
             F F+      +  +  A L  F +     L +N+++  ++ +  ++ P   N      
Sbjct: 130 RRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVT 189

Query: 168 YLLEV-----DASGWHQLPLGPEAQAACSQGHLTLELVLEGQ-------VAQSSVILGGA 215
            LL+      +AS W    + P      +QGH     V+E         V++  V +  +
Sbjct: 190 RLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRS 249

Query: 216 AH---------RPFVAARVRVGGKHQIHRRG---IDCQGGSRM---CCRQEFFVDFREIG 260
            H         RP +      G  H +H+R       +   R+   C R   +VDF ++G
Sbjct: 250 LHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVG 309

Query: 261 WHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPT 320
           W+DWI+ P GY   +C G+CP  +A    + ++ H  V  L+    +  +    +CCVPT
Sbjct: 310 WNDWIVAPPGYHAFYCHGECPFPLA--DHLNSTNHAIVQTLV---NSVNSKIPKACCVPT 364

Query: 321 ARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
               +S+LY D +  +V  +  DMVVE CGC
Sbjct: 365 ELSAISMLYLDENEKVVLKNYQDMVVEGCGC 395


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 46/113 (40%), Positives = 63/113 (55%), Gaps = 5/113 (4%)

Query: 242 GGSRMCCR-QEFFVDFREIGWHDWIIQPEGYAMNFCIGQC--PLHIAGMPGIAASFHTAV 298
           GG    CR +  +V FRE+GWH W+I P G+  N+C GQC  P+ ++G  G  A  H  +
Sbjct: 261 GGPGGACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPPALNHAVL 320

Query: 299 LNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
             L+ A  AA       CCVP    P+S+L++D   N+V     DMVV+ CGC
Sbjct: 321 RALMHA--AAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGC 371


>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 55/147 (37%), Positives = 70/147 (47%), Gaps = 6/147 (4%)

Query: 206 AQSSVILGGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDW 264
           A    ++GG   R    A  R   G      RG   +G SR C R+   VDF+E+GW DW
Sbjct: 308 ASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSR-CSRKPLHVDFKELGWDDW 366

Query: 265 IIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRP 324
           II P  Y    C G C   +     +  + H  +  LL  N+ A      SCCVP    P
Sbjct: 367 IIAPLDYEAYHCEGLCDFPLRSH--LEPTNHAIIQTLL--NSMAPDAAPASCCVPARLSP 422

Query: 325 LSLLYYDRDSNIVKTDIPDMVVEACGC 351
           +S+LY D  +N+V     DMVVEACGC
Sbjct: 423 ISILYIDAANNVVYKQYEDMVVEACGC 449


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 99/367 (26%), Positives = 145/367 (39%), Gaps = 66/367 (17%)

Query: 24  GQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHGVP 83
           G C AC       ++ +   ++  K  IL KL L   P +++ V R  L  A      + 
Sbjct: 37  GLCNACTWR----QNTKSSRIEAIKIQILSKLRLETAPNISKDVIRQLLPKAPPLRELID 92

Query: 84  Q----------GALLEDNREQECEIISFAETGLSTINQTR-----LDFHFSSDRTAGDRE 128
           Q          G+L +D+     E I    T    + Q         F FSS       +
Sbjct: 93  QYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYN--K 150

Query: 129 VQQASLMFFVQLPSNTTWTLKVRVLVL-----------GPHNTNLTL--ATQYLLEVDAS 175
           V +A L  +++ P  T  T+ V++L L           G  +  L +   T     +D  
Sbjct: 151 VVKAQLWIYLR-PVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVK 209

Query: 176 ----GWHQLP---LGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVG 228
                W + P   LG E +A    GH  L +   G         G     PF+  +V   
Sbjct: 210 TVLQNWLKQPESNLGIEIKALDENGH-DLAVTFPGP--------GEDGLNPFLEVKVTDT 260

Query: 229 GKHQIHRRGIDCQGGSR--MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCP-LHIA 285
            K      G+DC   S    CCR    VDF   GW DWII P+ Y  N+C G+C  + + 
Sbjct: 261 PKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGW-DWIIAPKRYKANYCSGECEFVFLQ 319

Query: 286 GMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMV 345
             P      HT +++      +AG      CC PT   P+++LY++    I+   IP MV
Sbjct: 320 KYP------HTHLVHQANPRGSAGP-----CCTPTKMSPINMLYFNGKEQIIYGKIPAMV 368

Query: 346 VEACGCS 352
           V+ CGCS
Sbjct: 369 VDRCGCS 375


>gi|10190670 growth differentiation factor 3 precursor [Homo
           sapiens]
          Length = 364

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 7/107 (6%)

Query: 246 MCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIA-GMPGIAASFHTAVLNLLKA 304
           +C R + F++FR++GWH WII P+G+  N+C G+CP  +   +     +F  A+++ +  
Sbjct: 263 LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDP 322

Query: 305 NTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
                     + C+PT   P+S+LY D + N++     DMVV+ CGC
Sbjct: 323 EIPQ------AVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 41/105 (39%), Positives = 58/105 (55%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C + E +V FR++GW DWII PEGYA  +C G+C   +     + A+ H  V  L+  + 
Sbjct: 330 CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSY--MNATNHAIVQTLV--HF 385

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
               T    CC PT    +S+LY+D  SN++     +MVV ACGC
Sbjct: 386 INPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 430


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 6/110 (5%)

Query: 243 GSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHI-AGMPGIAASFHTAVLNL 301
           G ++C R E +V F+++GW DW+I P+GY+  +C G+C   + + M     +   ++++L
Sbjct: 297 GRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHL 356

Query: 302 LKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
           +K N         +CC PT     S+LYYD  +N++     +MVV+ACGC
Sbjct: 357 MKPNAVP-----KACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 214 GAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAM 273
           G  H      R +   KH   R     +  ++ C R   +VDF ++GW+DWI+ P GY  
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQR----ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQA 334

Query: 274 NFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRD 333
            +C G CP  +A    + ++ H  V  L+    +  ++   +CCVPT    +S+LY D  
Sbjct: 335 FYCHGDCPFPLA--DHLNSTNHAIVQTLV---NSVNSSIPKACCVPTELSAISMLYLDEY 389

Query: 334 SNIVKTDIPDMVVEACGC 351
             +V  +  +MVVE CGC
Sbjct: 390 DKVVLKNYQEMVVEGCGC 407


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 214 GAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAM 273
           G  H      R +   KH   R     +  ++ C R   +VDF ++GW+DWI+ P GY  
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQR----ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQA 334

Query: 274 NFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRD 333
            +C G CP  +A    + ++ H  V  L+    +  ++   +CCVPT    +S+LY D  
Sbjct: 335 FYCHGDCPFPLA--DHLNSTNHAIVQTLV---NSVNSSIPKACCVPTELSAISMLYLDEY 389

Query: 334 SNIVKTDIPDMVVEACGC 351
             +V  +  +MVVE CGC
Sbjct: 390 DKVVLKNYQEMVVEGCGC 407


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 214 GAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAM 273
           G  H      R +   KH   R     +  ++ C R   +VDF ++GW+DWI+ P GY  
Sbjct: 279 GRGHALTRRRRAKRSPKHHSQR----ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQA 334

Query: 274 NFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRD 333
            +C G CP  +A    + ++ H  V  L+    +  ++   +CCVPT    +S+LY D  
Sbjct: 335 FYCHGDCPFPLA--DHLNSTNHAIVQTLV---NSVNSSIPKACCVPTELSAISMLYLDEY 389

Query: 334 SNIVKTDIPDMVVEACGC 351
             +V  +  +MVVE CGC
Sbjct: 390 DKVVLKNYQEMVVEGCGC 407


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C + E +V F+++GW DWII P+GYA N+C G+C   +     + A+ H  V  L+    
Sbjct: 412 CRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNA--HMNATNHAIVQTLVHLMN 469

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
                    CC PT    +S+LY+D +SN++     +MVV ACGC
Sbjct: 470 PEYVP--KPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
           sapiens]
          Length = 402

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 37/109 (33%), Positives = 61/109 (55%), Gaps = 4/109 (3%)

Query: 243 GSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLL 302
           G ++C R E +V F+++GW DW+I P+GY+  +C G+C   +     + A+ H  + +L+
Sbjct: 297 GRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSC--MNATNHAILQSLV 354

Query: 303 KANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
                       +CC PT     S+LYYD  +N++     +MVV+ACGC
Sbjct: 355 HLMMPDAVP--KACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401


>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
           sapiens]
          Length = 454

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 39/105 (37%), Positives = 56/105 (53%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C + E +V FR++GW DWII PEGYA  +C G+C   +     + A+ H  V  L+    
Sbjct: 353 CKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNA--HMNATNHAIVQTLVHLMF 410

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
                    CC PT    +S+LY+D  SN++     +MVV +CGC
Sbjct: 411 PDHVP--KPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C ++   V+F+E+GW DWII P  Y    C G C   +     +  + H  +  L+ +  
Sbjct: 354 CSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSH--LEPTNHAIIQTLMNSMD 411

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
              T    SCCVPT   P+S+LY D  +N+V     DMVVE+CGC
Sbjct: 412 PGSTPP--SCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGC 454


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 37/105 (35%), Positives = 55/105 (52%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C R+   V+F+++GW DWII P  Y    C G C   +     +  + H  +  L+ +  
Sbjct: 400 CSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSH--LEPTNHAVIQTLMNSMD 457

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
              T    +CCVPT   P+S+L+ D  +N+V     DMVVE+CGC
Sbjct: 458 PESTPP--TCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGC 500


>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
           sapiens]
          Length = 472

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 37/109 (33%), Positives = 57/109 (52%), Gaps = 7/109 (6%)

Query: 245 RMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA 304
           R C R+   VDF +IGW +WII P+ +   +C G C   +     +  S H  + ++++ 
Sbjct: 368 RNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMP--KSLKPSNHATIQSIVR- 424

Query: 305 NTAAGTTGG--GSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
             A G   G    CCVP     LS+L++D + N+V    P+M VE+C C
Sbjct: 425 --AVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCAC 471


>gi|4826740 growth differentiation factor 10 precursor [Homo
           sapiens]
          Length = 478

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 7/109 (6%)

Query: 245 RMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA 304
           R+C R+   VDF +IGW++WII P+ +   +C G C   +  +  +  S H  + ++++ 
Sbjct: 374 RVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKI--VRPSNHATIQSIVR- 430

Query: 305 NTAAGTTGG--GSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
             A G   G    CCVP     L +L+ D + N+V    P+M V+ C C
Sbjct: 431 --AVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCAC 477


>gi|4507465 transforming growth factor, beta 3 [Homo sapiens]
          Length = 412

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 40/107 (37%), Positives = 59/107 (55%), Gaps = 10/107 (9%)

Query: 247 CCRQEFFVDFRE-IGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKAN 305
           CC +  ++DFR+ +GW  W+ +P+GY  NFC G CP   +     A + H+ VL L   N
Sbjct: 315 CCVRPLYIDFRQDLGWK-WVHEPKGYYANFCSGPCPYLRS-----ADTTHSTVLGLY--N 366

Query: 306 TAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
           T         CCVP    PL++LYY   +  V+  + +MVV++C CS
Sbjct: 367 TLNPEASASPCCVPQDLEPLTILYYVGRTPKVE-QLSNMVVKSCKCS 412


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 4/105 (3%)

Query: 247 CCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANT 306
           C R   ++DF+EIGW  WII P GY    C G C   +A    +  + H  +  L+    
Sbjct: 323 CKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLA--EHLTPTKHAIIQALVHLKN 380

Query: 307 AAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
           +       +CCVPT   P+S+LY D+     K     M V  CGC
Sbjct: 381 S--QKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGC 423


>gi|222352098 nodal precursor [Homo sapiens]
          Length = 347

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 5/108 (4%)

Query: 244 SRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLK 303
           S++C + +F VDF  IGW  WII P+ Y    C G+CP  +        + H  + +LLK
Sbjct: 244 SQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVG--EEFHPTNHAYIQSLLK 301

Query: 304 ANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
                      +CC P   +PLS+LY D +  ++     DM+VE CGC
Sbjct: 302 RYQPHRVP--STCCAPVKTKPLSMLYVD-NGRVLLDHHKDMIVEECGC 346


>gi|63025222 transforming growth factor, beta 1 [Homo sapiens]
          Length = 390

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 14/124 (11%)

Query: 234 HRRGIDCQ----GGSRMCCRQEFFVDFR-EIGWHDWIIQPEGYAMNFCIGQCPLHIAGMP 288
           HRR +D         + CC ++ ++DFR ++GW  WI +P+GY  NFC+G CP +I  + 
Sbjct: 276 HRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWK-WIHEPKGYHANFCLGPCP-YIWSLD 333

Query: 289 GIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEA 348
               + ++ VL L   +    +     CCVP A  PL ++YY      V+  + +M+V +
Sbjct: 334 ----TQYSKVLALYNQHNPGAS--AAPCCVPQALEPLPIVYYVGRKPKVE-QLSNMIVRS 386

Query: 349 CGCS 352
           C CS
Sbjct: 387 CKCS 390


>gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 37/107 (34%), Positives = 59/107 (55%), Gaps = 10/107 (9%)

Query: 247 CCRQEFFVDF-REIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKAN 305
           CC +  ++DF R++GW  WI +P+GY  NFC G CP   +     + + H+ VL+L   N
Sbjct: 345 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACPYLWS-----SDTQHSRVLSLY--N 396

Query: 306 TAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
           T         CCV     PL++LYY   +  ++  + +M+V++C CS
Sbjct: 397 TINPEASASPCCVSQDLEPLTILYYIGKTPKIE-QLSNMIVKSCKCS 442


>gi|4507463 transforming growth factor, beta 2 isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 37/107 (34%), Positives = 59/107 (55%), Gaps = 10/107 (9%)

Query: 247 CCRQEFFVDF-REIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKAN 305
           CC +  ++DF R++GW  WI +P+GY  NFC G CP   +     + + H+ VL+L   N
Sbjct: 317 CCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACPYLWS-----SDTQHSRVLSLY--N 368

Query: 306 TAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 352
           T         CCV     PL++LYY   +  ++  + +M+V++C CS
Sbjct: 369 TINPEASASPCCVSQDLEPLTILYYIGKTPKIE-QLSNMIVKSCKCS 414


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 47/156 (30%), Positives = 65/156 (41%), Gaps = 10/156 (6%)

Query: 198 ELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFR 257
           E VL+      S   G ++H       V  G      +R     G    C +    V+F 
Sbjct: 281 ESVLKKLSKDGSTEAGESSHEEDTDGHVAAGSTLARRKRSA---GAGSHCQKTSLRVNFE 337

Query: 258 EIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCC 317
           +IGW  WII P+ Y    C G C   +A    +  + H  V  L+  +    T  G +CC
Sbjct: 338 DIGWDSWIIAPKEYEAYECKGGCFFPLA--DDVTPTKHAIVQTLV--HLKFPTKVGKACC 393

Query: 318 VPTARRPLSLLYYDRDSNI--VKTDIPDMVVEACGC 351
           VPT   P+S+LY D D  +  +K     M V  CGC
Sbjct: 394 VPTKLSPISVLYKD-DMGVPTLKYHYEGMSVAECGC 428


>gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]
          Length = 392

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 4/108 (3%)

Query: 244 SRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLK 303
           +  C    F + FR++GW  WII P  Y  N+C G C L +    G+ +  H  + NL+ 
Sbjct: 288 NNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTC-LRVL-RDGLNSPNHAIIQNLI- 344

Query: 304 ANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGC 351
            N     +     CVP    P+S+L  + + +I+  +   M+ E+C C
Sbjct: 345 -NQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTC 391


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,617,595
Number of Sequences: 37866
Number of extensions: 595089
Number of successful extensions: 1398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1310
Number of HSP's gapped (non-prelim): 48
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.