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Search of human proteins with 50053795
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
(611 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa... 1259 0.0
gi|11559923 eukaryotic translation initiation factor 4H isoform ... 97 6e-20
gi|14702180 eukaryotic translation initiation factor 4H isoform ... 89 2e-17
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 85 2e-16
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 78 2e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 71 3e-12
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 69 2e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 68 2e-11
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 64 3e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 64 4e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 64 4e-10
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 62 2e-09
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 61 3e-09
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 61 3e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 60 8e-09
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ... 59 1e-08
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 59 1e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 59 1e-08
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 59 1e-08
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens] 58 2e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 3e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 3e-08
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 58 3e-08
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 58 3e-08
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 5e-08
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 5e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 6e-08
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 1e-07
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 1e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 55 1e-07
>gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
Length = 611
Score = 1259 bits (3257), Expect = 0.0
Identities = 611/611 (100%), Positives = 611/611 (100%)
Query: 1 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD 60
MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
Sbjct: 1 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD 60
Query: 61 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN 120
DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
Sbjct: 61 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN 120
Query: 121 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD 180
ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
Sbjct: 121 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD 180
Query: 181 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG 240
DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
Sbjct: 181 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG 240
Query: 241 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED 300
YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
Sbjct: 241 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED 300
Query: 301 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI 360
RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
Sbjct: 301 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI 360
Query: 361 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT 420
FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
Sbjct: 361 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT 420
Query: 421 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK 480
GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
Sbjct: 421 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK 480
Query: 481 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT 540
ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
Sbjct: 481 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT 540
Query: 541 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG 600
GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
Sbjct: 541 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG 600
Query: 601 EDENEGEDYAE 611
EDENEGEDYAE
Sbjct: 601 EDENEGEDYAE 611
>gi|11559923 eukaryotic translation initiation factor 4H isoform 1
[Homo sapiens]
Length = 248
Score = 96.7 bits (239), Expect = 6e-20
Identities = 93/300 (31%), Positives = 134/300 (44%), Gaps = 85/300 (28%)
Query: 87 RSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFED 146
+ LP PPYTA++GNLP++ + I F+ L+I +VRL R+ + ++ KGF Y EF++
Sbjct: 33 QKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRD-KDTDKFKGFCYVEFDE 91
Query: 147 LDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATD 206
+DSL AL+ + LG+R +RVD+ A+ + +D FG + D
Sbjct: 92 VDSLKEALTYDGALLGDRSLRVDI---AEGRKQDKGGFGFRKGGPDD------------- 135
Query: 207 SFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDY 266
RG S + R +DS RD + G+RD D GGR GSR
Sbjct: 136 --------RGMGSSRES-RGGWDS---RDDFNSGFRD------DFLGGRG-----GSRPG 172
Query: 267 DRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRR-DD 325
DR R G GS +R RG S D+R +
Sbjct: 173 DR----RTGP---PMGSRFRDGPPLRG-----------------------SNMDFREPTE 202
Query: 326 RGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQE 385
QRP+L LKPR+ + A+ + ++IFGGA+P EE +QKEQE
Sbjct: 203 EERAQRPRLQLKPRTVATPLNQVANPN-----SAIFGGARP---------REEVVQKEQE 248
>gi|14702180 eukaryotic translation initiation factor 4H isoform 2
[Homo sapiens]
Length = 228
Score = 88.6 bits (218), Expect = 2e-17
Identities = 55/147 (37%), Positives = 81/147 (55%), Gaps = 20/147 (13%)
Query: 87 RSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFED 146
+ LP PPYTA++GNLP++ + I F+ L+I +VRL R+ + ++ KGF Y EF++
Sbjct: 33 QKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRD-KDTDKFKGFCYVEFDE 91
Query: 147 LDSLLSALSLNEESLGNRRIRVDVAD-QAQDK--------DRDDRSF------GRDRNRD 191
+DSL AL+ + LG+R +RVD+A+ + QDK DDR F GR +R
Sbjct: 92 VDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRP 151
Query: 192 SDKTDTDWRARPATDSFDDYPPRRGDD 218
D+ P F D PP RG +
Sbjct: 152 GDRR----TGPPMGSRFRDGPPLRGSN 174
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 84.7 bits (208), Expect = 2e-16
Identities = 109/463 (23%), Positives = 175/463 (37%), Gaps = 72/463 (15%)
Query: 158 EESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRR-- 215
E +R V + + ++ D+++ F RD N + D P D + DY R
Sbjct: 322 EPDFEEKRFTVTIGEDEREFDKENEVF-RDWNSRIPRDVRDTVLEPYADPYYDYEIERFW 380
Query: 216 ---GDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDS 272
++F +Y + YR+ R+ R+ +R+ +R RDR +R R+ +R +
Sbjct: 381 RGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERERE- 439
Query: 273 RIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRP 332
+ RD + + + +E +RD++ R D R+ R ++G P
Sbjct: 440 ------------HERDKERQRRKEEWERERAKRDEKDRQHR-DRDREKEREKEKGKP--- 483
Query: 333 KLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLD 392
KPRS P+ A + A + V A ++ R + ++KL +
Sbjct: 484 ----KPRS-PQPPSRQAEPPKKEAATT----GPQVKRADEWKDPWRRSKSPKKKLGVSV- 533
Query: 393 EPKLERRPRERHPSWRSEETQERERSRTG---------SESSQTGTSTTSSRNARRRESE 443
P RR R+ S S R SR+ S S + S+ SSR++R
Sbjct: 534 SPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593
Query: 444 KSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKE--NAWVKRSSNPPARSQSSDTE 501
S SPT P +P K PAPPP + VK+ + PPA Q++ T
Sbjct: 594 GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTT 653
Query: 502 QQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDR 561
P +P++ G R+ K P + S G G G +
Sbjct: 654 APVP----------EPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY-------- 695
Query: 562 KDGKKDQDSRSAPEPKKPEENPASKFSSA--SKYAALSVDGED 602
S S+ + + S SSA S +A SVD ED
Sbjct: 696 --------SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSED 730
Score = 58.9 bits (141), Expect = 1e-08
Identities = 92/426 (21%), Positives = 145/426 (34%), Gaps = 52/426 (12%)
Query: 176 DKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRD 235
+KDR R R++ R+ +K R+ P S PP++ + G + + +D ++D
Sbjct: 462 EKDRQHRDRDREKEREKEKGKPKPRS-PQPPSRQAEPPKKEAATTGPQVKR---ADEWKD 517
Query: 236 GYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAF--GSGYRRDDDYRG 293
+R + + R R + S +S S R + GSG R
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
Query: 294 GGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGP-PQRPKLNLKPRSTPKEDDSSASTS 352
Y R R S S S P P RP + K P + +
Sbjct: 578 SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSV 637
Query: 353 QSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEET 412
+ KP A + K + EP PRE R T
Sbjct: 638 K-----------KPAPPPA---------PPQATKTTAPVPEPTKPGDPREARRKERPART 677
Query: 413 QERERSRTGSESSQTGTSTTSSRNARRRE--SEKSLENETLNKE-------EDCHSPTSK 463
R R+ +GS S + + SS +R S S+ + T + ED ++ +
Sbjct: 678 PPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLAS 737
Query: 464 PPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSG----GGKVA--PAQP 517
P PA KE K+ + D+ Q P S GGK + P+ P
Sbjct: 738 PVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTP 797
Query: 518 SEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPK 577
+ PG+ + K N + D G+R ++ SD+ D +S P K
Sbjct: 798 QQAPPGQPQQGTFVAHKEIKLTLLNKA---ADKGSRKRYEPSDK-------DRQSPPPAK 847
Query: 578 KPEENP 583
+P +P
Sbjct: 848 RPNTSP 853
Score = 33.1 bits (74), Expect = 0.77
Identities = 66/332 (19%), Positives = 108/332 (32%), Gaps = 51/332 (15%)
Query: 172 DQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSD 231
D A+ +RD S D + +D D +D D R D ++ R S
Sbjct: 2 DVAESPERDPHS-PEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQ 60
Query: 232 RYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDY 291
D + D +DR S + DS + R S ++
Sbjct: 61 EEEDNHSDE------------------EDRASEPKSQDQDSEVNELSRGPTSSPCEEEGD 102
Query: 292 RGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRD-DRGPPQRPKLNLKPRSTPK---EDDS 347
G DR D RD+ S +R+ D++ D D P+ P ++ K EDD
Sbjct: 103 EGEEDRTSDL---RDEASSVTRE---LDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDE 156
Query: 348 SASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSW 407
G V + + +E +K++E ++D+ +++ E
Sbjct: 157 EKGEGTPREE-----GKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEV- 210
Query: 408 RSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKP 467
+ + + R R G T N +L + D P PP
Sbjct: 211 -KDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLG 269
Query: 468 DQPL------------KVMPAPPP---KENAW 484
PL +++P PPP E+AW
Sbjct: 270 PHPLMPANPWGGPVVDEILPPPPPEPPTESAW 301
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 78.2 bits (191), Expect = 2e-14
Identities = 113/506 (22%), Positives = 195/506 (38%), Gaps = 68/506 (13%)
Query: 99 FLGNLPYDVTEESIKEFFRGLN-ISAVRLPREPSNPERLKGFGYAEFEDL-DSLLSALSL 156
++G L Y E ++ FF+G I V L G+G+ EF+DL D+ + L
Sbjct: 5 YIGRLSYQARERDVERFFKGYGKILEVDLKN---------GYGFVEFDDLRDADDAVYEL 55
Query: 157 NEESLGNRRIRVDVA-----DQAQDKDRDDRSFGRD-RNRDSDKTDTDWR-------ARP 203
N + L R+ V+ A D + R + R R++ T T++R +R
Sbjct: 56 NGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRC 115
Query: 204 ATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRD-GYRDGYRDGPRRDMDRYGGR------D 256
+ DY + G+ ++ D ++ R + Y D R + D GR D
Sbjct: 116 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED 175
Query: 257 RYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDY 316
+ R R Y R SR S R+ S + R R G + R RS S
Sbjct: 176 KPGSRRRRSYSR---SRSHSRSRS-RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 317 SRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQS------------------TRAA 358
SR + R ++ + K +S + + S S+S +R+
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 359 SIFGGAKPVDTAAREREVEE---------RLQKEQEKLQRQLDEPKLERRPRERHPSWRS 409
S + ++ER VEE R Q++ + R K R R R S
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 410 EETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQ 469
++ + R+RSR ES S + S +R+R S++ + + K++ + S+ P +
Sbjct: 352 DKRKGRKRSRE--ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSR 409
Query: 470 PLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENK 529
+ E++ +R + + ++ E +S + K P PSE K +K
Sbjct: 410 SVSKEREHAKSESS--QREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASK 467
Query: 530 VDGMNAPKGQTGNSSRGPGDGGNRDH 555
+ K ++ ++SR P +R H
Sbjct: 468 T--RSRSKSRSRSASRSPSRSRSRSH 491
Score = 53.5 bits (127), Expect = 5e-07
Identities = 87/383 (22%), Positives = 130/383 (33%), Gaps = 38/383 (9%)
Query: 254 GRDRYDDRGSRDYDRG--YDSRIGSGRRAFGSGYRRDD-DYRGGGDRYEDRY--DRRDDR 308
G+D +R ++ RG D GSGR G GYRR D G R E R + R
Sbjct: 57 GKDLCGERVIVEHARGPRRDGSYGSGRS--GYGYRRSGRDKYGPPTRTEYRLIVENLSSR 114
Query: 309 -SWSSRDDYSRD----DYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGG 363
SW DY R Y +G + S K ++
Sbjct: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
Query: 364 AKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSE 423
KP +R R R + R + R+ R R S +S ++ R RSR+GS
Sbjct: 175 DKP---GSRRRRSYSRSRSHSRSRSRS----RHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 424 SSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVM---PAPPPK 480
S S + SR+ ++E +S E + K K+ PK
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 481 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQP---------SEEGPGRKDENKVD 531
+ + S +RS+S + + G +Q S G + ++
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 532 GMNAPKGQTGNSSRGPGDGGNRDHWK-ESDRKDGKKDQDSRSAPEPKKPEENPASKFSSA 590
+ K + SR +R K E RK G K + + KK E+ S+ S
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 591 SKYA------ALSVDGEDENEGE 607
S+ A S + E GE
Sbjct: 408 SRSVSKEREHAKSESSQREGRGE 430
Score = 47.4 bits (111), Expect = 4e-05
Identities = 57/265 (21%), Positives = 93/265 (35%), Gaps = 41/265 (15%)
Query: 172 DQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSD 231
DQA++K +++ + G+ ++R + + ++R + +RG S G
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK----- 325
Query: 232 RYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDY 291
R R + G R R SR + D R GR+ R
Sbjct: 326 --------SLRQSRSRSRSKGGSRSR-----SRSRSKSKDKR--KGRKRSREESRSRSRS 370
Query: 292 RGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSAST 351
R +R R +RD ++ SS+ D R R P RS KE + + S
Sbjct: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS---------RSVSKEREHAKSE 421
Query: 352 SQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEE 411
S G + A +E R + + +P L R R S
Sbjct: 422 SSQRE------GRGESENAGTNQETRSRSRSNSKS------KPNLPSESRSRSKSASKTR 469
Query: 412 TQERERSRTGSESSQTGTSTTSSRN 436
++ + RSR+ S S S + SR+
Sbjct: 470 SRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 70.9 bits (172), Expect = 3e-12
Identities = 93/426 (21%), Positives = 170/426 (39%), Gaps = 41/426 (9%)
Query: 175 QDKDRDDRSFGR--DRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRY---- 228
+D D DDR R +R R +K T+ + + R D ++ RDR
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 229 -DSDRYRDGYRDGYRDGPR---RDMDRYG--GRDRYDDRGSRDYDRGYDSRIGSGRRAFG 282
+DR RD R+ R+ + R+ +R G GRDR D G R+ +R D+ R+
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTD-GQRERERQRDAEKERERQTDR 165
Query: 283 SGYRRDDDYRGGG-DRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNL----- 336
R+ + R +R ++R +RR+ +++ + D R +RG + +
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTED--RHSERGRERERERETETETE 223
Query: 337 KPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAA-----REREVEERLQKEQEKLQRQL 391
+ R T +E D T + + A +T RER+ + + Q++ +RQ
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 392 DEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETL 451
D + R R+R + E +ERER R + + R R+RE+E+ E E
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE-RQRETERDREKERE 342
Query: 452 NKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSS---DTEQQSPTSG 508
K + + + D+ + A +R QS+ + ++
Sbjct: 343 RKRK-------RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 509 GGKVAPAQPSEEGPGRKDENK----VDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDG 564
K Q ++ G+++ K + +G+ R G RD +++DR+ G
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
Query: 565 KKDQDS 570
++ + S
Sbjct: 456 RQRKRS 461
Score = 58.9 bits (141), Expect = 1e-08
Identities = 82/400 (20%), Positives = 149/400 (37%), Gaps = 43/400 (10%)
Query: 163 NRRIRVDVADQAQDKDR-DDRSFGRDRNRDSDK-TDTDWRARPATDSFDDYPPRRGDDSF 220
NR+ R + Q + +++ +DR R R R+ ++ T+T+ + TD D +
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT----- 238
Query: 221 GDKYRDRYDSDRYRDGYRDGYRDGPR-RDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRR 279
++ R++ ++R R R+ RD R R+ DR RDR R DR R R
Sbjct: 239 -EREREK-QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
Query: 280 AFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPR 339
R + + +R +R +R+ R+ + + RD +R + R
Sbjct: 297 T-----ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR----KR 347
Query: 340 STPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERR 399
T + + + T + R + RERE E Q +E+ +R+ D + ++
Sbjct: 348 QTEMDRERNRQTGREGRRQA---------ERERERERERDRQSAREREERERDRDRDRQK 398
Query: 400 PRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHS 459
RER + E+ R G ++ R + R + +E D
Sbjct: 399 ERER----------QTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448
Query: 460 PTSKP---PKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQ 516
T + + L V P P + V+ N P R + + P + + +
Sbjct: 449 QTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGR 508
Query: 517 PSEEGPGRKDENK--VDGMNAPKGQTGNSSRGPGDGGNRD 554
P++ GR + + +GQ G R G G +
Sbjct: 509 PAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTEN 548
Score = 53.9 bits (128), Expect = 4e-07
Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 22/219 (10%)
Query: 238 RDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDR 297
R G ++ PRR R G+ D G DR + + RR R+ D + R
Sbjct: 30 RPGSQESPRR---RGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRERRR 83
Query: 298 YEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRA 357
+DR+ +RD R + D ++ R+ DR +R + K R+ KE + + T
Sbjct: 84 EKDRHRKRD-RHRERQRDREKERERQTDR---ERDRQREKERNRQKERE------RETER 133
Query: 358 ASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLER-RPRERHPSWRSEETQERE 416
G + D RERE + +KE+E+ + + + ER R +ER +E +ERE
Sbjct: 134 EGERGRDRQTD-GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE 192
Query: 417 RSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEE 455
R R + T S R RE E+ E ET K +
Sbjct: 193 RQR----EKENKTEDRHSERGRERERERETETETERKRQ 227
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/240 (18%), Positives = 92/240 (38%), Gaps = 26/240 (10%)
Query: 368 DTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQT 427
D R R+ E ++E+ + +R+ D + RR ++RH + + +ER+R R QT
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHR--KRDRHRERQRDREKERERQT 109
Query: 428 GTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKR 487
R + R +K E ET + E + + + + A +E +
Sbjct: 110 DRERDRQRE-KERNRQKERERETEREGERGRDRQTDGQRERE--RQRDAEKERERQTDRE 166
Query: 488 SSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGP 547
R++ + E++ + E R+ ENK + ++ +G+
Sbjct: 167 RQRQTERNRQKEREREKNRQ--------ERRERERQREKENKTEDRHSERGR-------- 210
Query: 548 GDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGE 607
R+ +E++ + +K Q R +K E K + + + + + E E E
Sbjct: 211 ----ERERERETETETERKRQTDRERDRQRKTERE-REKQAERERASERETERDKERERE 265
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/466 (20%), Positives = 167/466 (35%), Gaps = 59/466 (12%)
Query: 156 LNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRR 215
L EES IR + ++++ + R+DR GR R R + + R +
Sbjct: 534 LREES-SRTEIRNESRNESRSEIRNDR-MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSN 591
Query: 216 GDDSFGDKY----RDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYD 271
DS+ + RDRY RD RD + + DR R+R S +G +
Sbjct: 592 YHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRN 651
Query: 272 SRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQR 331
+ R R DD R R DR +R DR + RD R +R +R
Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDR-ERERDRERERERERERDREREKER-ELER 709
Query: 332 PKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQL 391
+ + R KE D + RER+ E+ ++E+E+ +R+
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRER---------ERERERDREKEREREREERERER 760
Query: 392 DEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETL 451
+ + R RER E +ERER R + + R+ RR + E+ E+
Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDK-------GRDDRREKREEIREDRNP 813
Query: 452 NKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGK 511
D +R S R++ S + +QSP
Sbjct: 814 RDGHD-----------------------------ERKSKKRYRNEGSPSPRQSPKRRREH 844
Query: 512 VAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSR 571
+ G + +++++ ++ + S + WKE DRK +K+ R
Sbjct: 845 SPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR 904
Query: 572 SAPEPKKPEENPASK------FSSASKYAALSVDGEDENEGEDYAE 611
+ K + + K +S+ A + G ++E + ++
Sbjct: 905 YEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSD 950
Score = 54.7 bits (130), Expect = 2e-07
Identities = 101/481 (20%), Positives = 165/481 (34%), Gaps = 52/481 (10%)
Query: 155 SLNEESLGNRRIRVDVADQAQDKDRDDRSFGR---DRNRDSDKTDTDWRARPATDSFDDY 211
SL + S +R + A KDR + D+ R+S KT+ + P T S
Sbjct: 211 SLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS-KTNQSKKKGPRTPS--PP 267
Query: 212 PPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYD 271
PP D + G KY+++Y + +D + RDG R GRD R RD R
Sbjct: 268 PPIPEDIALGKKYKEKY---KVKDRIEEKTRDGKDR------GRDFERQREKRDKPRS-T 317
Query: 272 SRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRD-------DRSWSSRDDYSRDDYRRD 324
S G S + G + RR R+ + S Y
Sbjct: 318 SPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSH 377
Query: 325 DRGPPQRPKLNLKPRSTPKE----DDSSASTSQSTRAASIFGGAKPVDTAA-REREVEER 379
PQR + + RS +E D S S R + DT R+RE + R
Sbjct: 378 SLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHE------RREDTRGKRDREKDSR 431
Query: 380 LQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERER------SRTGSESSQTGTSTTS 433
++E E+ Q + + +R PR+ + +T++R R E T
Sbjct: 432 EEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKE 491
Query: 434 SRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPA 493
SR+ R S + + + D H P+ + ++ S +
Sbjct: 492 SRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNES 551
Query: 494 RSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNR 553
RS+ + ++ + G P + S G + ++ N SS R
Sbjct: 552 RSEIRN-DRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSY-----PER 605
Query: 554 DHWKESDRKDGKKDQD------SRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGE 607
D + E D +D +D R + ++ ++ P+S + L D E
Sbjct: 606 DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRV 665
Query: 608 D 608
D
Sbjct: 666 D 666
Score = 47.0 bits (110), Expect = 5e-05
Identities = 48/230 (20%), Positives = 94/230 (40%), Gaps = 25/230 (10%)
Query: 382 KEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRE 441
KE+ K++ +++E + + R R + ++R++ R+ S + Q + +S ++ +
Sbjct: 281 KEKYKVKDRIEEKTRDGKDRGRD---FERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQ 337
Query: 442 SEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNP-PARSQSSDT 500
S S++ HSP+ + + P PP ++RS++P P+ S SS
Sbjct: 338 SGSSIQR---------HSPSPRRKRTPSPSYQRTLTPP-----LRRSASPYPSHSLSSPQ 383
Query: 501 EQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESD 560
+QSP P E GR D + + + + +RG D +
Sbjct: 384 RKQSPPRH------RSPMRE-KGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREY 436
Query: 561 RKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYA 610
+D +D R EP+ + ++ + + S D D E DY+
Sbjct: 437 EQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYS 486
Score = 43.1 bits (100), Expect = 7e-04
Identities = 54/226 (23%), Positives = 78/226 (34%), Gaps = 25/226 (11%)
Query: 238 RDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDR 297
R D R D GR R GSRD ++ I R++ R D + G
Sbjct: 1207 RSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKS------RIDQLKRGEPS 1260
Query: 298 YEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRA 357
DR+D RS SSR D + R + L+ R + D + TR
Sbjct: 1261 RSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR- 1319
Query: 358 ASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERER 417
+RE + K+ R D +L R RER R + +ERER
Sbjct: 1320 ---------------QREWDRDADKDWP---RNRDRDRLRERERERERDKRRDLDRERER 1361
Query: 418 SRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSK 463
+ S + + + ES K E + + E TS+
Sbjct: 1362 LISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSR 1407
Score = 33.9 bits (76), Expect = 0.45
Identities = 44/215 (20%), Positives = 82/215 (38%), Gaps = 20/215 (9%)
Query: 279 RAFGSGYRRDDDYRGGGDRYEDRYDRRDD---RSWSSRDDYSRDDYRRDDRGPPQRPKLN 335
+ + S YRR + R GD E ++R D + S R++ R K +
Sbjct: 68 KGYSSNYRRSPE-RPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKED 126
Query: 336 LKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPK 395
+K + + T G D E L+ +++K+QR+L + +
Sbjct: 127 IKITKERTPESEEENVEWETNRDDSDNGDINYDYVH-----ELSLEMKRQKIQRELMKLE 181
Query: 396 LERRPRERHPSWRSEETQERERS--------RTGSESSQTGTSTTSSRNARRRESEKSLE 447
E + + E + E RS R S+S + +S SS +++ ++
Sbjct: 182 QENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVS 241
Query: 448 NETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKEN 482
+ L+++ + + SK P P P PP E+
Sbjct: 242 SPLLDQQRNSKTNQSKKKGPRTP---SPPPPIPED 273
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 68.2 bits (165), Expect = 2e-11
Identities = 84/446 (18%), Positives = 145/446 (32%), Gaps = 9/446 (2%)
Query: 169 DVADQAQDKDRDDRSF-GRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDR 227
D +D D + D + G + N D+DK+D+ ++DS D DS D
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS-DSSDSSNSSDSSDSSDSDS 571
Query: 228 YDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRR 287
DS+ D D D + D S D DS S ++ S
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 288 DD-DYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDD 346
D D D + D S SS D S D + S+ D
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSS--DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 347 SSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPS 406
S +S S ++ +S + D++ + + S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 407 WRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLEN----ETLNKEEDCHSPTS 462
S ++ + S S+SS + S+ SS ++ +S S + ++ N + +S S
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 463 KPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGP 522
+ ++ SSN S SSD+ S + + + S+
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 523 GRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEEN 582
N D ++ ++S D N SD + DS ++ + + +
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 583 PASKFSSASKYAALSVDGEDENEGED 608
+ SS S ++ S D D + D
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSD 955
Score = 65.5 bits (158), Expect = 1e-10
Identities = 116/618 (18%), Positives = 211/618 (34%), Gaps = 62/618 (10%)
Query: 23 EDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAARE 82
E+ G G S+ SK D + + D S +S+ + Y P +
Sbjct: 265 EEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYD------------PEGKED 312
Query: 83 PN--IDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFG 140
P+ +D + KS +A +P D + I++ + + + R+ + G
Sbjct: 313 PHNEVDGDKTSKSEENSA---GIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVG 369
Query: 141 YAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWR 200
++ + ++ + S GNR I +V + K+ D G + + KT +
Sbjct: 370 KSQDKGIE-------IKGPSSGNRNITKEVGKGNEGKE-DKGQHGMILGKGNVKTQGEVV 421
Query: 201 ARPATDSFDDYPPRRGDDSFG-DKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDR-- 257
+ + G + G D D YDS + D G D P + G D
Sbjct: 422 NIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG--DDPNSSDESNGNDDANS 479
Query: 258 -------------YDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDR 304
Y+ S+D G DS+ + + + D G G+ D D+
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK 539
Query: 305 RDD---RSWSSRDDYSRDDYRRD--DRGPPQRPKLNLKPRSTPKEDDSSAS----TSQST 355
D +S SS D S D D N S + DSS S +S S+
Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 356 RAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQER 415
++ + D++ + + + + + K + S + ++ +
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 416 ERSRTGSESSQTGTSTTSSRNA-RRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVM 474
S S+SS + S+ SS ++ S+ S +++ N E S S
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD----- 714
Query: 475 PAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKD----ENKV 530
+ N+ SSN S SS++ S +S + + S + D +
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 531 DGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSA 590
D ++ N S D + + +S D S + ++ S SS
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 591 SKYAALSVDGEDENEGED 608
S ++ S D D ++G D
Sbjct: 835 SSNSSDSSDSSDSSDGSD 852
Score = 65.5 bits (158), Expect = 1e-10
Identities = 85/453 (18%), Positives = 144/453 (31%), Gaps = 15/453 (3%)
Query: 169 DVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRY 228
D +D + D D S D DS K+++D + + D D S D
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESD--SSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 229 DSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSG---- 284
+S D D D D S + DS S + S
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 285 -YRRDDDYRGGGDRYE-----DRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKP 338
D D D + D D D + S D S D +
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 339 RSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLER 398
S+ D S++S S + +S + ++ + + + D
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 399 RPRERHPSWRSE-ETQERERSRTGSESSQTGTSTTSSRNARRRES-EKSLENETLNKEED 456
S S+ ++ R S S+SS + S+ SS ++ +S E S +++ +
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 457 CHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQ 516
S +S + E++ +SN S SSD+ S +S + +
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 517 PSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGG-NRDHWKESDRKDGKKDQDSRSAPE 575
S D N D ++ + S D + D SD D DS ++ +
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 576 PKKPEENPASKFSSASKYAALSVDGEDENEGED 608
++ S SS S ++ S D D ++ D
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Score = 64.3 bits (155), Expect = 3e-10
Identities = 88/488 (18%), Positives = 158/488 (32%), Gaps = 23/488 (4%)
Query: 145 EDLDSLLSALSLNEESLGNRRIRVDVADQAQ---------DKDRDDRSFGRDRNRDSDKT 195
ED DS ++ + N +S GN D D++ D D D S D + SD
Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570
Query: 196 DTDWRARPATDSFDDYPPRRGDDSFGDKYR--------DRYDSDRYRDGYRDGYRDGPRR 247
+D + +DS D D D D DS D D D +
Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSKSDSSKS 629
Query: 248 DMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDD 307
+ D + D S D +S + S D D + D
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 308 RSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPV 367
S + S D + ++ D S++S S + +S +
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 368 DTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQT 427
++ + + + + + S S ++ + S S SS +
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 428 GTSTTSSRNARRRESEKSLENETL---NKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAW 484
S+ SS + S+ S +++ N + S S + +++
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 485 VKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMN-APKGQTGNS 543
SSN S SSD+ + S +S + + S+ + D N + ++ NS
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 544 SRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDE 603
S + + SD D DS ++ + ++ S SS S ++ S D D
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN-SSDSSDSSNSSDSSDS 988
Query: 604 NEGEDYAE 611
++ D ++
Sbjct: 989 SDSSDSSD 996
Score = 63.9 bits (154), Expect = 4e-10
Identities = 87/466 (18%), Positives = 151/466 (32%), Gaps = 12/466 (2%)
Query: 148 DSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDS 207
DS S+ S N + D +D + D +D S D + S+ +D+ + ++DS
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS-NSSDSSDS 812
Query: 208 FDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG-YRDGPRRDM-DRYGGRDRYDDRGSRD 265
D + S D DS D DG D +R + D S D
Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Query: 266 YDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDD 325
DS S + D D + D S+ D S D+
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 326 RGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQE 385
+ S+ + S +S S + +S + D++ + +
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 386 KLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKS 445
D + S S ++ S S+SS + S+ SS ++ +S S
Sbjct: 993 DSSDSSDSSNSS----DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 446 LENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSP 505
++ + D + D + E++ SSN S SSD+ S
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 506 TSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGK 565
+S + + S D + ++ + NSS + D SD D
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSD----SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 566 KDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYAE 611
DS + + + S SS S ++ S D D ++ D ++
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Score = 61.2 bits (147), Expect = 3e-09
Identities = 87/483 (18%), Positives = 149/483 (30%), Gaps = 11/483 (2%)
Query: 132 NPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRD 191
N + G G ++ D DS S S + +S + ++ + D D D + D
Sbjct: 537 NDKSDSGKGKSDSSDSDS--SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 192 SDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDR 251
S + + ++DS D DS D + DS D D D
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD-SDSKSDSSDSNSSDSSDN 653
Query: 252 YGGRDRYDDRGSRDYDRGYDSR-IGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSW 310
D + S D DS S + S D D D D S
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 311 SSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTA 370
S D + + D + S+ D S++S S + +S + D++
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS--NSSDSSDSS 771
Query: 371 AREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEET----QERERSRTGSESSQ 426
+ + D + S S+ + + S S SS
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 427 TGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVK 486
+ S+ SS ++ +S ++++ N+ + +S S +
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Query: 487 RSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKD-ENKVDGMNAPKGQTGNSSR 545
S+ + S SD+ S +S + + S E D N D N+ + S
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Query: 546 GPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENE 605
D N S DS + ++ S SS S ++ S D D ++
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 606 GED 608
D
Sbjct: 1012 SSD 1014
Score = 61.2 bits (147), Expect = 3e-09
Identities = 83/467 (17%), Positives = 150/467 (32%), Gaps = 29/467 (6%)
Query: 145 EDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPA 204
E DS S+ S + +S + +D + D D S D + SD +++
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS------- 752
Query: 205 TDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSR 264
+DS D DS D DS D + D + D S
Sbjct: 753 SDSSDSSDSSNSSDS-----SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 265 DYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRD 324
D DS + S D D D D S D +R D
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSS---DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 325 DRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQ 384
N S + + S+++S S+ +++ + + + +
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN-----------SSDSDSSDSSNSSD 913
Query: 385 EKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEK 444
+ + S S + + S S SS + S+ SS ++ +S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 445 SLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQS 504
S +++ N + S S + +++ SSN S SSD+ S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 505 PTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDG 564
+S + + S + D + ++ + +SS + D + SD D
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSN-SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090
Query: 565 KKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYAE 611
DS + + ++ S SS S ++ S D D ++ D ++
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 50.4 bits (119), Expect = 5e-06
Identities = 89/469 (18%), Positives = 164/469 (34%), Gaps = 46/469 (9%)
Query: 167 RVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
+V + D A +R + + D+N + +D P G ++ D +
Sbjct: 139 QVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDE 198
Query: 227 RYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286
++ +G P+ + R G ++ G+ + D G D+ GS G+G
Sbjct: 199 IIENSCRNEGNTSEIT--PQINSKRNGTKEAEVTPGTGE-DAGLDNSDGSPS---GNGAD 252
Query: 287 RDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTP--KE 344
D+D G GD ++ D S +S+ +D + DD + K P KE
Sbjct: 253 EDED-EGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKE 311
Query: 345 DDSSASTSQSTRAASIFGGAKPVDTAAREREVEERL-QKEQEKLQRQLDEPKLERRPRER 403
D + T + P D ++ E ++L +E ++++ ++ + E
Sbjct: 312 DPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRI------TKESET 365
Query: 404 HPSWRSEE---------------TQERERSRTGSESSQTGTSTTSSRNARRRESEKSLEN 448
H +S++ T+E + G E N + + ++E
Sbjct: 366 HAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEG 425
Query: 449 ETLNKE---EDCHSPTSKPPKPDQ------PLKVMPAPPPKENAWVKRSSNPPARSQSSD 499
E + HS T D K M P N+ + + N A S+S
Sbjct: 426 PGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDP--NSSDESNGNDDANSES-- 481
Query: 500 TEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNS-SRGPGDGGNRDHWKE 558
+ S + G + + G G + D + T NS S G G+ GN D+ K
Sbjct: 482 -DNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS 540
Query: 559 SDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGE 607
K DS S+ + + +S S+ ++ D D + +
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/402 (17%), Positives = 118/402 (29%), Gaps = 23/402 (5%)
Query: 171 ADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDS 230
+D ++ + D S D + SD +D+ + ++DS + DS D DS
Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN-SSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 231 DRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDD 290
D D D D S D DS S S D
Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD-----SSNSSDSS 1034
Query: 291 YRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSAS 350
D D D S+ D S D + S+ D S++S
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 351 TSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSE 410
S + +S + ++ + + + S S
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 411 ETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQP 470
++ + S S+SS + S+ SS ++ +S S ++ + D + D
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS- 1213
Query: 471 LKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKV 530
SS+ S SSD+ + +S + + S D +
Sbjct: 1214 ---------------SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDS 1258
Query: 531 DGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRS 572
+ +S G+G N +SD +G S S
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSD-SEGSDSNHSTS 1299
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 64.3 bits (155), Expect = 3e-10
Identities = 75/263 (28%), Positives = 108/263 (41%), Gaps = 36/263 (13%)
Query: 198 DWRARPATDSFDDYPPRRGDDSFGDKYRDRYDS---DRYRDGYRDGYRDGPR---RDMDR 251
D + R A+ S ++ R D D+ RDR S DR R RD R G R R +
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 252 YGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGG---DRYEDRYDRRDDR 308
R+R RD +R + + R G+RRD D + R +D R+D
Sbjct: 67 SAERERRHKERERDKERDRNKK---DRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKD-- 121
Query: 309 SWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKP-- 366
RD ++ D+ P +P L+L+ K+ + A AKP
Sbjct: 122 ----RDSKKDEEDEHGDKKPKAQP-LSLEELLAKKKAEEEAE-------------AKPKF 163
Query: 367 VDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERER--SRTGSES 424
+ A RE E +R Q+E E+ QR L+E + +R+ + E+ QERER R E
Sbjct: 164 LSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMER 223
Query: 425 SQTGTSTTSSRNARRRESEKSLE 447
G R R E +KS E
Sbjct: 224 ETNGNEDEEGRQKIREEKDKSKE 246
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/200 (22%), Positives = 77/200 (38%), Gaps = 6/200 (3%)
Query: 371 AREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTS 430
A +++ + KE+ K R D + R R+ PS + + R+R R GS S S
Sbjct: 6 ADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRS 65
Query: 431 TTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSN 490
++ R R +E E+ E + K+ D + K + + P + R S
Sbjct: 66 KSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSK 125
Query: 491 PPARSQSSDTEQQS-PTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGD 549
+ D + ++ P S +A + EE E K ++ + + R +
Sbjct: 126 KDEEDEHGDKKPKAQPLSLEELLAKKKAEEEA-----EAKPKFLSKAEREAEALKRRQQE 180
Query: 550 GGNRDHWKESDRKDGKKDQD 569
R E +RK K+ QD
Sbjct: 181 VEERQRMLEEERKKRKQFQD 200
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 63.9 bits (154), Expect = 4e-10
Identities = 95/414 (22%), Positives = 163/414 (39%), Gaps = 40/414 (9%)
Query: 68 IDRSILPTAPRAAREPNIDRSRLPKSPPY--------------TAFLGNL-PYDVTEESI 112
+ S L P AA +PNI PP T ++GNL T + +
Sbjct: 140 VSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQL 199
Query: 113 KEFFRGLN-ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVA 171
EFF+ + + VR+ + + P R F + EF D +S+ AL+ N G+R ++++ +
Sbjct: 200 LEFFKQVGEVKFVRMAGDETQPTR---FAFVEFADQNSVPRALAFNGVMFGDRPLKINHS 256
Query: 172 DQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFD-DYPPRRGDDSFGDKYRDRYDS 230
+ A K + + + + R R A P G + R R
Sbjct: 257 NNAIVKPPEMTPQAAAKELE----EVMKRVREAQSFISAAIEPESGKSNERKGGRSR--- 309
Query: 231 DRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRG-SRDYDRGYDSRIGSGRRAFGSGYRRDD 289
R R + RR + R R +R SR DR S+ +R+ R+
Sbjct: 310 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRERRKSR 368
Query: 290 DYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSA 349
D+ +D ++ ++ D ++ R +R + N K R +E D
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN-KDRDKEREKDREK 427
Query: 350 STSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEK-LQRQLDEPKLERR-----PRER 403
+ K D +E+E E+ +KE+EK +++DE + + + PR
Sbjct: 428 DKEKDREREREKEHEKDRD---KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 404 HPSWRS-EETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEED 456
+ S RS ++ER R R+ S S TS T R + R S +S + +E++
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Score = 34.3 bits (77), Expect = 0.34
Identities = 40/201 (19%), Positives = 77/201 (38%), Gaps = 16/201 (7%)
Query: 382 KEQEKLQRQLDEPKLERRPRERHPSWRSEETQE-RERSRTGSESSQTGTSTTSSRNARRR 440
KE E++ +++ E + S +S E + R RS T S+S ++S ++RR+
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSR-----SSSKSHSRRK 327
Query: 441 ESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDT 500
S+ + + N+ + P + K K S +R + DT
Sbjct: 328 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS-------KSRERRKSRSRSHSRDKRKDT 380
Query: 501 EQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESD 560
++ K + E +++ K G N + + R +R+ +E
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE-- 438
Query: 561 RKDGKKDQDSRSAPEPKKPEE 581
K+ +KD+D E K +E
Sbjct: 439 -KEHEKDRDKEKEKEQDKEKE 458
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 63.9 bits (154), Expect = 4e-10
Identities = 95/414 (22%), Positives = 163/414 (39%), Gaps = 40/414 (9%)
Query: 68 IDRSILPTAPRAAREPNIDRSRLPKSPPY--------------TAFLGNL-PYDVTEESI 112
+ S L P AA +PNI PP T ++GNL T + +
Sbjct: 24 VSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQL 83
Query: 113 KEFFRGLN-ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVA 171
EFF+ + + VR+ + + P R F + EF D +S+ AL+ N G+R ++++ +
Sbjct: 84 LEFFKQVGEVKFVRMAGDETQPTR---FAFVEFADQNSVPRALAFNGVMFGDRPLKINHS 140
Query: 172 DQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFD-DYPPRRGDDSFGDKYRDRYDS 230
+ A K + + + + R R A P G + R R
Sbjct: 141 NNAIVKPPEMTPQAAAKELE----EVMKRVREAQSFISAAIEPESGKSNERKGGRSR--- 193
Query: 231 DRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRG-SRDYDRGYDSRIGSGRRAFGSGYRRDD 289
R R + RR + R R +R SR DR S+ +R+ R+
Sbjct: 194 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRERRKSR 252
Query: 290 DYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSA 349
D+ +D ++ ++ D ++ R +R + N K R +E D
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN-KDRDKEREKDREK 311
Query: 350 STSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEK-LQRQLDEPKLERR-----PRER 403
+ K D +E+E E+ +KE+EK +++DE + + + PR
Sbjct: 312 DKEKDREREREKEHEKDRD---KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 404 HPSWRS-EETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEED 456
+ S RS ++ER R R+ S S TS T R + R S +S + +E++
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Score = 34.3 bits (77), Expect = 0.34
Identities = 40/201 (19%), Positives = 77/201 (38%), Gaps = 16/201 (7%)
Query: 382 KEQEKLQRQLDEPKLERRPRERHPSWRSEETQE-RERSRTGSESSQTGTSTTSSRNARRR 440
KE E++ +++ E + S +S E + R RS T S+S ++S ++RR+
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSR-----SSSKSHSRRK 211
Query: 441 ESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDT 500
S+ + + N+ + P + K K S +R + DT
Sbjct: 212 RSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS-------KSRERRKSRSRSHSRDKRKDT 264
Query: 501 EQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESD 560
++ K + E +++ K G N + + R +R+ +E
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE-- 322
Query: 561 RKDGKKDQDSRSAPEPKKPEE 581
K+ +KD+D E K +E
Sbjct: 323 -KEHEKDRDKEKEKEQDKEKE 342
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 61.6 bits (148), Expect = 2e-09
Identities = 103/433 (23%), Positives = 152/433 (35%), Gaps = 76/433 (17%)
Query: 215 RGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRD-RYDDRGSRDYDRGYDSR 273
R S + R RYR R R R DR RD R D R +R R Y
Sbjct: 16 RSQSSSRSRSRSHSRKKRYRSRSRTYSRS---RSRDRMYSRDYRRDYRNNRGMRRPY--- 69
Query: 274 IGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPK 333
G R G GY Y+GGG RY R W+ R S R R P +R
Sbjct: 70 ---GYRGRGRGY-----YQGGGGRYHRGGYR---PVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 334 LNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDE 393
+ + RS + S+ + +S+ + S +K + R + ++ + E E + +
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
Query: 394 PKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNK 453
K + P++ SE E +S S G S N
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD------------------NS 220
Query: 454 EEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSP-TSGGGKV 512
HSP+ P Q AP + V + N P SQ S + Q SP SG G V
Sbjct: 221 PRSPHSPSPIATPPSQSSSCSDAP---MLSTVHSAKNTP--SQHSHSIQHSPERSGSGSV 275
Query: 513 -------APAQ--PSEEGPGRKDENK-VDGMNAPKGQTGNSSRGPGDGGNR--------- 553
+P+Q P P R+ K + NAP+ ++ S DGG++
Sbjct: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
Query: 554 -------------DHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFS--SASKYAALSV 598
D D++ K+ + E + ++ FS + K
Sbjct: 336 KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDS 395
Query: 599 DGEDENEGEDYAE 611
+G+D E EDY +
Sbjct: 396 EGDDTEETEDYRQ 408
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRE--RHPSWRSEETQERERSRTGSESSQTGT 429
R R+ + + + + + K E+ P++ + S++ + +RE+ + S SS
Sbjct: 697 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASP 756
Query: 430 STTSSRNARRRESEKSLENETLN--KEEDCHSPTSKP 464
S+ SSR + + E+ E +T + KE + S+P
Sbjct: 757 SSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 793
Score = 31.6 bits (70), Expect = 2.2
Identities = 87/497 (17%), Positives = 168/497 (33%), Gaps = 87/497 (17%)
Query: 167 RVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
RV + D+ +D++ +++ + + + +W + A D F D G F D D
Sbjct: 344 RVFLLDRGNTRDKEA---SKEKGSEKGRAEGEWEDQEALDYFSD--KESGKQKFNDSEGD 398
Query: 227 RYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286
D++ D YR +R D + + R + + Y S++ G+R
Sbjct: 399 --DTEETED-YRQ-FRKSVLADQGKSFATASH--RNTEEEGLKYKSKVSLKGNRESDGFR 452
Query: 287 RDDDYRGGGDRY--------EDRY---DRRDDRSWSSRDDYSRDDYRRD------DRGPP 329
+ +Y+ Y +D++ D+ +R ++ S + + + D PP
Sbjct: 453 EEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPP 512
Query: 330 QRPKLNLKPRSTPKEDD----SSASTSQSTRAASIFGGAKPVDTAAREREV-EERL---- 380
L+ + +ST +E+ ++ + P+D + R + ++RL
Sbjct: 513 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 572
Query: 381 ----QKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRN 436
K++++ + D KL + + SE + S Q S + N
Sbjct: 573 LVHSVKKEQEFRSIFDHIKLPQASKS-----TSESFIQHIVSLVHHVKEQYFKSAAMTLN 627
Query: 437 ARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWV---------KR 487
R +K+ E HS K P+ + + + P+ K +
Sbjct: 628 ERFTSYQKATEE---------HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQ 678
Query: 488 SSNPPARSQSSD--------TEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQ 539
+ R S+D +++S G K + E RK E K
Sbjct: 679 KGDKKLRCDSADLRHDIDRRRKERSKERGDSKGS----RESSGSRKQEKTPKDYKEYKSY 734
Query: 540 TGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALS-- 597
+S +DH + S SR E KK E +Y+ +
Sbjct: 735 KDDSKH----KREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGV 790
Query: 598 -----VDGEDENEGEDY 609
+D ++G DY
Sbjct: 791 SRPRGTFHDDRDDGVDY 807
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 61.2 bits (147), Expect = 3e-09
Identities = 103/433 (23%), Positives = 152/433 (35%), Gaps = 76/433 (17%)
Query: 215 RGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRD-RYDDRGSRDYDRGYDSR 273
R S + R RYR R R R DR RD R D R +R R Y
Sbjct: 16 RSQSSSRSRSRSHSRKKRYRSRSRTYSRS---RSRDRMYSRDYRRDYRNNRAMRRPY--- 69
Query: 274 IGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPK 333
G R G GY Y+GGG RY R W+ R S R R P +R
Sbjct: 70 ---GYRGRGRGY-----YQGGGGRYHRGGYR---PVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 334 LNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDE 393
+ + RS + S+ + +S+ + S +K + R + ++ + E E + +
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
Query: 394 PKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNK 453
K + P++ SE E +S S G S N
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD------------------NS 220
Query: 454 EEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSP-TSGGGKV 512
HSP+ P Q AP + V + N P SQ S + Q SP SG G V
Sbjct: 221 PRSPHSPSPIATPPSQSSSCSDAP---MLSTVHSAKNTP--SQHSHSIQHSPERSGSGSV 275
Query: 513 -------APAQ--PSEEGPGRKDENK-VDGMNAPKGQTGNSSRGPGDGGNR--------- 553
+P+Q P P R+ K + NAP+ ++ S DGG++
Sbjct: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
Query: 554 -------------DHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFS--SASKYAALSV 598
D D++ K+ + E + ++ FS + K
Sbjct: 336 KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDS 395
Query: 599 DGEDENEGEDYAE 611
+G+D E EDY +
Sbjct: 396 EGDDTEETEDYRQ 408
Score = 33.5 bits (75), Expect = 0.59
Identities = 34/158 (21%), Positives = 72/158 (45%), Gaps = 14/158 (8%)
Query: 319 DDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAK-PVDTAAREREVE 377
+++ + P ++++ P ST ++D A + + + G K D+A +++
Sbjct: 638 EEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 696
Query: 378 ERLQKEQEK-------LQRQLDEPKLERRPRE--RHPSWRSEETQERERSRTGSESSQTG 428
R +KE+ K + K E+ P++ + S++ + +RE+ + S SS
Sbjct: 697 HR-RKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSAS 755
Query: 429 TSTTSSRNARRRESEKSLENETLN--KEEDCHSPTSKP 464
S+ SSR + + E+ E +T + KE + S+P
Sbjct: 756 PSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 793
Score = 30.0 bits (66), Expect = 6.5
Identities = 40/210 (19%), Positives = 81/210 (38%), Gaps = 33/210 (15%)
Query: 167 RVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
RV + D+ +D++ +++ + + + +W + A D F D G F D D
Sbjct: 344 RVFLLDRGNTRDKEA---SKEKGSEKGRAEGEWEDQEALDYFSD--KESGKQKFNDSEGD 398
Query: 227 RYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286
D++ D YR +R D + + R + + Y S++ G R
Sbjct: 399 --DTEETED-YRQ-FRKSVLADQGKSFATASH--RNTEEEGLKYKSKVSL------KGNR 446
Query: 287 RDDDYRGGGDRYEDRYDRRDDRSW-SSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKED 345
D +R E++ D+ + + R ++D ++ +D+ R T K++
Sbjct: 447 ESDGFR------EEKNDKHKETGYVVERPSTTKDKHKEEDKN---------SERITVKKE 491
Query: 346 DSSASTSQSTRAASIFGGAKPVDTAARERE 375
S +S + +F + P+ RE
Sbjct: 492 TQSPEQVKSEKLKDLFDYSPPLHKNLDARE 521
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 61.2 bits (147), Expect = 3e-09
Identities = 97/405 (23%), Positives = 145/405 (35%), Gaps = 71/405 (17%)
Query: 247 RDMDRYGGRDRYDDRG-SRDYDRGYDSRIGS----GRRAFGSGYRRDDDYRGGGDRYEDR 301
R R R R DR SRDY R Y + G G R G GY Y+GGG RY
Sbjct: 37 RSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGY-----YQGGGGRYHRG 91
Query: 302 YDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIF 361
R W+ R S R R P +R + + RS + S+ + +S+ + S
Sbjct: 92 GYR---PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148
Query: 362 GGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTG 421
+K + R + ++ + E E + + K + P++ SE E +S
Sbjct: 149 PYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSAT 208
Query: 422 SESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKE 481
S G S N HSP+ P Q AP
Sbjct: 209 SGDIWPGLSAYD------------------NSPRSPHSPSPIATPPSQSSSCSDAP---M 247
Query: 482 NAWVKRSSNPPARSQSSDTEQQSP-TSGGGKV-------APAQ--PSEEGPGRKDENK-V 530
+ V + N P SQ S + Q SP SG G V +P+Q P P R+ K +
Sbjct: 248 LSTVHSAKNTP--SQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTI 305
Query: 531 DGMNAPKGQTGNSSRGPGDGGNR----------------------DHWKESDRKDGKKDQ 568
NAP+ ++ S DGG++ D D++ K+
Sbjct: 306 APQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKG 365
Query: 569 DSRSAPEPKKPEENPASKFS--SASKYAALSVDGEDENEGEDYAE 611
+ E + ++ FS + K +G+D E EDY +
Sbjct: 366 SEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ 410
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRE--RHPSWRSEETQERERSRTGSESSQTGT 429
R R+ + + + + + K E+ P++ + S++ + +RE+ + S SS
Sbjct: 699 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASP 758
Query: 430 STTSSRNARRRESEKSLENETLN--KEEDCHSPTSKP 464
S+ SSR + + E+ E +T + KE + S+P
Sbjct: 759 SSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 795
Score = 31.2 bits (69), Expect = 2.9
Identities = 83/460 (18%), Positives = 165/460 (35%), Gaps = 69/460 (15%)
Query: 167 RVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
RV + D+ +D++ +++ + + + +W + A D F D G F D D
Sbjct: 346 RVFLLDRGNTRDKEA---SKEKGSEKGRAEGEWEDQEALDYFSD--KESGKQKFNDSEGD 400
Query: 227 RYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286
D++ D YR +R D + + R + + Y S++ G+R
Sbjct: 401 --DTEETED-YRQ-FRKSVLADQGKSFATASH--RNTEEEGLKYKSKVSLKGNRESDGFR 454
Query: 287 RDDDYRGGGDRY--------EDRY---DRRDDRSWSSRDDYSRDDYRRD------DRGPP 329
+ +Y+ Y +D++ D+ +R ++ S + + + D PP
Sbjct: 455 EEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPP 514
Query: 330 QRPKLNLKPRSTPKEDD----SSASTSQSTRAASIFGGAKPVDTAAREREV-EERL---- 380
L+ + +ST +E+ ++ + P+D + R + ++RL
Sbjct: 515 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 574
Query: 381 ----QKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRN 436
K++++ + D KL + + SE + S Q S + N
Sbjct: 575 LVHSVKKEQEFRSIFDHIKLPQASKS-----TSESFIQHIVSLVHHVKEQYFKSAAMTLN 629
Query: 437 ARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQ 496
R +K+ E HS K P+ + + + P+ K +Q
Sbjct: 630 ERFTSYQKATEE---------HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQ 680
Query: 497 SSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHW 556
D + + ++ + E R D KG +S + +D+
Sbjct: 681 KGDKKLRCDSADLRHDIDRRRKERSKERGDS---------KGSRESSGSRKQEKTPKDYK 731
Query: 557 KESDRKDG---KKDQD-SRSAPEPKKPEENPASKFSSASK 592
+ KD K++QD SRS+ P +P+S+ SK
Sbjct: 732 EYKSYKDDSKHKREQDHSRSSSSSASP-SSPSSREEKESK 770
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 59.7 bits (143), Expect = 8e-09
Identities = 88/351 (25%), Positives = 131/351 (37%), Gaps = 67/351 (19%)
Query: 296 DRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQST 355
D +D+ D+ + S + + SR RR R P R RS+P + S S+S
Sbjct: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR------RSSPVRRERKRSHSRSP 201
Query: 356 RAASIFGGAKPVDTAARER--------EVEERLQKEQEKLQRQLDEPKLER--RPRERHP 405
R + P + +V+E +E L PK E P+E P
Sbjct: 202 RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP 261
Query: 406 SWRSEETQERERSRTGSESSQTGTSTTSSRNA-----RRRESEKSLENETLNKEEDCHSP 460
S++ +E+E++R S S S T SR+ RRR +S + SP
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP----SP 317
Query: 461 TSKP-PKPDQPLKVMPAPPPKENAWVKRSSNPPAR------------SQSSDTEQQSP-- 505
+P P+ P + MP PPP+ +RS +P R S SS + +SP
Sbjct: 318 RRRPSPRRRTPPRRMP-PPPRH----RRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK 372
Query: 506 ------TSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKG------QTGNSSR------GP 547
+S K PS P R+ PK Q N +R P
Sbjct: 373 KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
Query: 548 GDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSV 598
G R K + K +K + AP+P+K E + + + AA SV
Sbjct: 433 G----RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479
Score = 54.3 bits (129), Expect = 3e-07
Identities = 86/369 (23%), Positives = 131/369 (35%), Gaps = 52/369 (14%)
Query: 259 DDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSR 318
+D+ RD + SR R S RR R R RR+ + SR R
Sbjct: 149 EDKDKRDKEEKESSR--EKRERSRSPRRRKS--RSPSPRRRSSPVRRERKRSHSRSPRHR 204
Query: 319 DDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEE 378
R P ++ K P + K + S + ST +P+ +E E+
Sbjct: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP-KEPSPEK 263
Query: 379 RLQKEQEKLQ---RQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTS----- 430
+KE+EK + R K R R R PS + R RSR+ S S + S
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS--HTRPRRRHRSRSRSYSPRRRPSPRRRP 321
Query: 431 ------------------TTSSRNARRRESEKSLENETLNKEED-CHSPTSKPPK----- 466
+ S RRR S SL + + SP KPPK
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
Query: 467 PDQPLKVMP-APPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRK 525
P + ++ P A PP+ + PP +++ S T QQS + +V+ + G K
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTK 441
Query: 526 ---DENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKES---------DRKDGKKDQDSRSA 573
E + APK + S D G + +S + D S S+
Sbjct: 442 HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS 501
Query: 574 PEPKKPEEN 582
E ++P+ +
Sbjct: 502 SEDERPKRS 510
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 8/199 (4%)
Query: 382 KEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTS-SRNARRR 440
K++E QRQ+++ KL ++ + ++ +E+E SR E S++ S S + RRR
Sbjct: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDK-EEKESSREKRERSRSPRRRKSRSPSPRRR 185
Query: 441 ESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDT 500
S E + + H S+ P P K P+ + VK S A S S
Sbjct: 186 SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL 245
Query: 501 EQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESD 560
+ P P +PS E +K++ K P+ ++ + SR + H +
Sbjct: 246 KVPKPEP---IPEPKEPSPEKNSKKEKEK--EKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
Query: 561 R-KDGKKDQDSRSAPEPKK 578
R + + R P P++
Sbjct: 301 RHRSRSRSYSPRRRPSPRR 319
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/237 (23%), Positives = 94/237 (39%), Gaps = 26/237 (10%)
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWR---SEETQERERSRTGSESSQTG 428
++ + ++R ++E+E + + + + RR + R PS R S +ER+RS + S +T
Sbjct: 147 QDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK 206
Query: 429 TSTTSSRNARRRESEKSLENETLNKEEDCHSPTS-----KPPKPDQPLKVMPAPPPKENA 483
+ + S ++ ++ + E KE TS K PKP +P+ P P++N+
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKP-EPIPEPKEPSPEKNS 265
Query: 484 ---WVKRSSNPPARSQS---SDTEQQSPT---------SGGGKVAPAQPSEEGPGRKDEN 528
K + P +RS+S S T +SP+ S +P +
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR 325
Query: 529 KVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPAS 585
+ P SR P R S SRS PKKP + +S
Sbjct: 326 RTPPRRMPPPPRHRRSRSPVRRRRRS--SASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
Score = 43.5 bits (101), Expect = 6e-04
Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 24/262 (9%)
Query: 338 PRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLE 397
P PK S S+ + GG + ++R + R Q +Q +
Sbjct: 451 PSPAPKPRKVELSESEEDK-----GGKMAAADSVQQRR-QYRRQNQQSSSDSGSSSSSED 504
Query: 398 RRPRERHPSWRSEETQERER---SRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKE 454
RP+ H ++ E R R SR+ S S + TS R RRR S
Sbjct: 505 ERPKRSHV--KNGEVGRRRRHSPSRSASPSPRKRQKETSPRG-RRRRSPSPPPTRRRRSP 561
Query: 455 EDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAP 514
P + P + P+PPP+ + R +PP + + S SP +P
Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS----PSPPPKRRTASP 617
Query: 515 AQPSEE--GPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRS 572
P + P + +V PK ++ ++ + H K S + +++RS
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS--SPSRSTREARS 675
Query: 573 APEPKK---PEENPASKFSSAS 591
P+P K P P + +S+S
Sbjct: 676 -PQPNKRHSPSPRPRAPQTSSS 696
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/279 (20%), Positives = 105/279 (37%), Gaps = 14/279 (5%)
Query: 322 RRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQ 381
RR PP+R + + S P + S S R AS P A+ + R+
Sbjct: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS--PPPPPKRRASPSPPPKRRVS 636
Query: 382 KEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRE 441
QR K R PS S+ + SR+ E+ + S + R R
Sbjct: 637 HSPPPKQRSSPVTK------RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 442 SEKSLENETLNKEEDCHSPTSKPPKPD-QPLK-VMPAPPPKENAWVKRSSNPPARSQSSD 499
+ S + + + P P +P++ V P PK+ +K++++P +S
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKK---IKKAASPSPQSVRRV 747
Query: 500 TEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNA-PKGQTGNSSRGPGDGGNRDHWKE 558
+ +S + A P+ P + + A P + + + P N D
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGG 807
Query: 559 SDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALS 597
+K KKD+ + + KK +++ K +A+ AA++
Sbjct: 808 GKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT 846
>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
64kDa, tau variant [Homo sapiens]
Length = 616
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/104 (35%), Positives = 61/104 (58%), Gaps = 13/104 (12%)
Query: 79 AAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGL-NISAVRL--PREPSNPER 135
A R+P +DRS + F+GN+PY+ TEE +K+ F + ++ + RL RE P
Sbjct: 5 AVRDPAMDRSLR------SVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKP-- 56
Query: 136 LKGFGYAEFEDLDSLLSAL-SLNEESLGNRRIRVDVADQAQDKD 178
KG+G+ E++D ++ LSA+ +LN R +RVD A ++K+
Sbjct: 57 -KGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKE 99
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 58.9 bits (141), Expect = 1e-08
Identities = 105/418 (25%), Positives = 149/418 (35%), Gaps = 81/418 (19%)
Query: 180 DDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRG-DDSFGDKY---RDRYD---SDR 232
+DRS RD R D + R P+ DD PRRG DD G + DR+ +D
Sbjct: 926 EDRSHRRDEERPRRLGDDEDR-EPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADD 984
Query: 233 YRDGYRDGYRDGPRR---DMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGS-GYRR- 287
R +R+ D P R D DR R DDR R RG D GS R A G RR
Sbjct: 985 DRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPR---RGLDEDRGSWRTADEDRGPRRG 1041
Query: 288 -DDDY---RGGGDRYEDRYDRRDDRSWSSR---DDYSRDDYRRDDRGPPQRPKLNLKPRS 340
DDD RGG D + DD R DD DDRGP + + PR
Sbjct: 1042 MDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRR 1101
Query: 341 TPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRP 400
+D R P A +R + R ++ R +D+ +L RR
Sbjct: 1102 GMDDDRGPRRGLDDDRG--------PWRNADDDR-IPRRGAEDDRGPWRNMDDDRLSRRA 1152
Query: 401 RERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSP 460
+ +R + S+ G + RE EK+ E
Sbjct: 1153 DD-------------DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESW---------- 1189
Query: 461 TSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEE 520
PP+ +P +E W R + D + Q P E
Sbjct: 1190 --GPPRESRP--------SEEREW--------DREKERDRDNQDREEND-----KDPERE 1226
Query: 521 GPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKK 578
+D ++ D P+ + G RGP + + W++S R+D + D R + ++
Sbjct: 1227 RDRERDVDREDRFRRPRDE-GGWRRGPAEESSS--WRDSSRRDDRDRDDRRRERDDRR 1281
Score = 55.8 bits (133), Expect = 1e-07
Identities = 112/433 (25%), Positives = 160/433 (36%), Gaps = 87/433 (20%)
Query: 170 VADQAQDKDRDDR---SFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
V + D DR R R R +D WR ++ DD PPRR D +R
Sbjct: 957 VPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWR-----NTDDDRPPRRIADEDRGNWRH 1011
Query: 227 RYDS-------DRYRDGYRDGYRD-GPRRDMD-----RYGG--------RDRYDDRGSR- 264
D D R +R D GPRR MD R GG R+ DDRG R
Sbjct: 1012 ADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR 1071
Query: 265 --DYD----RGYDSRIG---------SGRRAFGS--GYRR--DDDYRGGGDRYEDRYDRR 305
D D RG D G RR G RR DDD + +DR RR
Sbjct: 1072 GLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRR 1131
Query: 306 ---DDRS-WSSRDD--YSR--DDYRRDDRGPPQRP---KLNLKP---RSTPKEDDSSAST 351
DDR W + DD SR DD R RG RP + +KP R K + S
Sbjct: 1132 GAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGP 1191
Query: 352 SQSTRAAS--IFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRS 409
+ +R + + K D ++RE ++ + + +R +D RRPR+ WR
Sbjct: 1192 PRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRD-EGGWRR 1250
Query: 410 EETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPD- 468
+E S + +SS+ R R + E L + D P + + +
Sbjct: 1251 GPAEE---SSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEV 1307
Query: 469 ---------QPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSE 519
+ +V PP R PPA S+ + ++ G + A + +
Sbjct: 1308 SSWRRADDRKDDRVEERDPP-------RRVPPPALSRDRERDRDREREGEKEKASWRAEK 1360
Query: 520 EGPG-RKDENKVD 531
+ R+ +N+ D
Sbjct: 1361 DRESLRRTKNETD 1373
Score = 47.8 bits (112), Expect = 3e-05
Identities = 48/199 (24%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 369 TAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTG 428
T RE+E EE+ + E++ L+ + + + ER RE E QER + E +
Sbjct: 805 TYYREKEEEEQRRAEEQMLKEREERERAERAKREE----ELREYQERVKKLEEVERKKRQ 860
Query: 429 TSTTSSRNARRRESEKSLENETLNKEE------DCHSPTSKPPKPDQPLKVMPAPPPKEN 482
RRRE E+ L + +L++++ D K P+ D + PP KE
Sbjct: 861 RELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWR--RGPPEKE- 917
Query: 483 AWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPA-QPSEEGPGRKDENKVDGMNAPKGQTG 541
W + RS D E+ P+ +P ++ R+ + G +
Sbjct: 918 -WRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDR 976
Query: 542 NSSRGPGDGGNRDHWKESD 560
S RG D +R W+ +D
Sbjct: 977 FSRRGADD--DRPSWRNTD 993
Score = 45.4 bits (106), Expect = 1e-04
Identities = 58/296 (19%), Positives = 116/296 (39%), Gaps = 26/296 (8%)
Query: 299 EDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRA- 357
E+R++R ++R +++ YR + +R + + +E A + R
Sbjct: 785 EERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREY 844
Query: 358 ASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERR-----PRERHPSWRSEET 412
+ V+ R+RE+E ++ + + +R+L + L R+ R+ +WR
Sbjct: 845 QERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPE 904
Query: 413 QERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLK 472
+ E R E + RR+ E+ L +ED P+ +P P +
Sbjct: 905 ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERP---RRLGDDED-REPSLRPDDDRVPRR 960
Query: 473 VM-----PAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDE 527
M P P+E+ + +R ++ S + + + P ++A D
Sbjct: 961 GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPR----RIADEDRGNWRHADDDR 1016
Query: 528 NKVDGMNAPKG--QTGNSSRGPGDGGNRDHWKESDRKDGKKDQDS--RSAPEPKKP 579
G++ +G +T + RGP G + D R+ G D+ S R+A + + P
Sbjct: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDD---RGPRRGGADDERSSWRNADDDRGP 1069
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/178 (32%), Positives = 71/178 (39%), Gaps = 38/178 (21%)
Query: 157 NEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDT--------DWRARPATDSF 208
+EE +R D +Q ++++ D RDR RD D+ D WR PA +S
Sbjct: 1198 SEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESS 1257
Query: 209 DDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDR 268
R DD RDR D R RD RRD+ R+R D R RD R
Sbjct: 1258 SWRDSSRRDD------RDRDDRRRERD---------DRRDL-----RERRDLRDDRD-RR 1296
Query: 269 GYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDR 326
G R R S +RR D DR +DR + RD SRD R DR
Sbjct: 1297 GPPLR---SEREEVSSWRRAD------DRKDDRVEERDPPRRVPPPALSRDRERDRDR 1345
Score = 38.9 bits (89), Expect = 0.014
Identities = 53/202 (26%), Positives = 78/202 (38%), Gaps = 8/202 (3%)
Query: 246 RRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRR---DDDYRGGGDRYEDRY 302
RR+ +R G + SR DR + G A S +RR + ++R G R EDR
Sbjct: 871 RREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEA-DSEWRRGPPEKEWRRGEGRDEDRS 929
Query: 303 DRRD-DRSWSSRDDYSRDDYRR--DDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAA- 358
RRD +R DD R+ R DDR P + + PR P+ED S + R +
Sbjct: 930 HRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSW 989
Query: 359 SIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERS 418
+P A E R + +R LDE + R + R +R
Sbjct: 990 RNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPR 1049
Query: 419 RTGSESSQTGTSTTSSRNARRR 440
R G++ ++ RR
Sbjct: 1050 RGGADDERSSWRNADDDRGPRR 1071
Score = 30.8 bits (68), Expect = 3.8
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Query: 371 AREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSE------ETQERERSRTGSES 424
AR + +EER ++ E L Q ++ +LE+R E ++E E +ERE+ R E
Sbjct: 570 ARRQTIEERKER-LESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEH 628
Query: 425 SQTGTSTTSSRNARRRESE 443
Q T R + +++E
Sbjct: 629 EQIKKKTVRERLEQIKKTE 647
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 58.9 bits (141), Expect = 1e-08
Identities = 83/366 (22%), Positives = 148/366 (40%), Gaps = 43/366 (11%)
Query: 110 ESIKEFFRGLNISAVRLPREP------------SNPERLKGFGYAEFEDLDSLLSALSLN 157
E ++ F L + PR P + P ++K G E++D +
Sbjct: 202 EMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSR 261
Query: 158 E--ESLGNRRIRVDVADQAQDKD-RDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPR 214
SL RR ++ ++ SF R+ R+ ++ + R A + +
Sbjct: 262 SPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLE---REAKEREKERRRS 318
Query: 215 RGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRI 274
R D ++ R R +R+R R R G RRD DR R++ ++RG R DR YD
Sbjct: 319 RSIDRGLERRRSR-SRERHRSRSRSRDRKGDRRDRDRE--REKENERGRRR-DRDYDKER 374
Query: 275 GSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYR-RDDRGPPQRPK 333
G+ R+ + +R +++ R + ++D +DD R RDD+ ++ K
Sbjct: 375 GN---------EREKERERSRERSKEQRSRGEVEEKKHKED--KDDRRHRDDKRDSKKEK 423
Query: 334 LNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDE 393
+ + RS ++ S S+S A ++ + E +E+ K + +
Sbjct: 424 KHSRSRSRERKH---RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD 480
Query: 394 PKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESE----KSLENE 449
+ + RE PS E++++R RS+ S S S RR S+ +S E +
Sbjct: 481 SVEKSKKREHSPS--KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Query: 450 TLNKEE 455
NK+E
Sbjct: 539 HKNKDE 544
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/315 (20%), Positives = 119/315 (37%), Gaps = 33/315 (10%)
Query: 290 DYRGGGDRYEDRYDRRDDRS--------WSSRDDYSRDDYRRDDRGPPQRPKLNLKPRST 341
D + G + + +RR RS S R SR +R +L +
Sbjct: 243 DGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQ 302
Query: 342 PKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLE---- 397
E ++ + R+ SI G + + +RER ++++ +R D + +
Sbjct: 303 RLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362
Query: 398 --RRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEE 455
RR R+ +E +ERERSR S+ ++ ++ ++ + +++ +K+E
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422
Query: 456 DCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPA 515
HS + + + RS N RS+S E+ S K
Sbjct: 423 KKHSRSRSRERKHRSR--------------SRSRNAGKRSRSRSKEKSSKHKNESKEKSN 468
Query: 516 QPSEEG-PGRKD---ENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSR 571
+ S G GR D ++K + K ++ SR RDH D+ D K D+
Sbjct: 469 KRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSD-KHDRRRS 527
Query: 572 SAPEPKKPEENPASK 586
+ E + E+ +K
Sbjct: 528 QSIEQESQEKQHKNK 542
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 58.9 bits (141), Expect = 1e-08
Identities = 92/361 (25%), Positives = 132/361 (36%), Gaps = 55/361 (15%)
Query: 247 RDMDRYGGRDRYDDRG-SRDYDRGYDSRIGS----GRRAFGSGYRRDDDYRGGGDRYEDR 301
R R R R DR SRDY R Y + G G R G GY Y+GGG RY
Sbjct: 37 RSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGY-----YQGGGGRYHRG 91
Query: 302 YDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIF 361
R W+ R S R R P +R + + RS + S+ + +S+ + S
Sbjct: 92 GYR---PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148
Query: 362 GGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTG 421
+K + R + ++ + E E + + K + P++ SE E +S
Sbjct: 149 PYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSAT 208
Query: 422 SESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKE 481
S G S N HSP+ P Q AP
Sbjct: 209 SGDIWPGLSAYD------------------NSPRSPHSPSPIATPPSQSSSCSDAP---M 247
Query: 482 NAWVKRSSNPPARSQSSDTEQQSP-TSGGGKV-------APAQ--PSEEGPGRKDENK-V 530
+ V + N P SQ S + Q SP SG G V +P+Q P P R+ K +
Sbjct: 248 LSTVHSAKNTP--SQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTI 305
Query: 531 DGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSA 590
NAP+ ++ S DGG D++ K + +S P K + S F
Sbjct: 306 APQNAPRDESRGRSSFYPDGG--------DQETAKTGKFLKSPPLHKNLDAREKSTFREE 357
Query: 591 S 591
S
Sbjct: 358 S 358
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRE--RHPSWRSEETQERERSRTGSESSQTGT 429
R R+ + + + + + K E+ P++ + S++ + +RE+ + S SS
Sbjct: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASP 585
Query: 430 STTSSRNARRRESEKSLENETLN--KEEDCHSPTSKP 464
S+ SSR + + E+ E +T + KE + S+P
Sbjct: 586 SSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 622
>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
Length = 577
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 13/102 (12%)
Query: 81 REPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN-ISAVRL--PREPSNPERLK 137
R+P +DRS + F+GN+PY+ TEE +K+ F + + + RL RE P K
Sbjct: 7 RDPAVDRSLR------SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKP---K 57
Query: 138 GFGYAEFEDLDSLLSAL-SLNEESLGNRRIRVDVADQAQDKD 178
G+G+ E++D ++ LSA+ +LN R +RVD A ++K+
Sbjct: 58 GYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKE 99
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 57.8 bits (138), Expect = 3e-08
Identities = 92/434 (21%), Positives = 166/434 (38%), Gaps = 53/434 (12%)
Query: 206 DSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMD---------RYGGRD 256
D DD GDD+FGD DR G R G D D G+D
Sbjct: 100 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGG---NSRLGSDEDSDDTIQASEESAPQGQD 156
Query: 257 RYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDD--YRGGGDRYEDRY---DRRDDRSWS 311
D S + + R+ S S + + + GGG E + DD
Sbjct: 157 SAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQ 216
Query: 312 SRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAA 371
S D S R +RG + +K + + E+ A+T S GG++ ++ +
Sbjct: 217 SDDPES----IRSERGNSRMNSAGMKSKES-GENSEQANTQDS-------GGSQLLEHPS 264
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEET---QERERSRTGS-ESSQT 427
R+ + R+ +E ++ + D +E + + S +T Q R S+ S E S+
Sbjct: 265 RKIFRKSRISEEDDRSELD-DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 323
Query: 428 GTSTTSSRNARRRESEKSLENETLNKEEDCHS-----PTSKPPKPDQPLKVMPAPPPKEN 482
S S+N SE S E ++E S S+ PD + ++
Sbjct: 324 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383
Query: 483 AWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGN 542
+ + SS+ + S+S E+Q+ + + ++ S E P ++ + +G+ Q+ +
Sbjct: 384 S-EEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGL-----QSHS 437
Query: 543 SSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG-- 600
SS + +SD +D + ++ ++ E K E + + L+VD
Sbjct: 438 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYH 497
Query: 601 ------EDENEGED 608
+D+N+ +D
Sbjct: 498 NKPIGDQDDNDCQD 511
Score = 35.4 bits (80), Expect = 0.15
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 12/118 (10%)
Query: 502 QQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQ-----TGNSSRGPGDGGNRDHW 556
+ S +S G KV+ + + E P +++ +G+ + Q G SR G GG+
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSE-EGLGSDDHQYIYRLAGGFSRSTGKGGDD--- 101
Query: 557 KESDRKDGKKDQ--DSRSAPEPKKPEENPASKF-SSASKYAALSVDGEDENEGEDYAE 611
K+ D D D D S P PK +E S+ S + E +G+D A+
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQ 159
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 57.8 bits (138), Expect = 3e-08
Identities = 92/434 (21%), Positives = 166/434 (38%), Gaps = 53/434 (12%)
Query: 206 DSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMD---------RYGGRD 256
D DD GDD+FGD DR G R G D D G+D
Sbjct: 84 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGG---NSRLGSDEDSDDTIQASEESAPQGQD 140
Query: 257 RYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDD--YRGGGDRYEDRY---DRRDDRSWS 311
D S + + R+ S S + + + GGG E + DD
Sbjct: 141 SAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQ 200
Query: 312 SRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAA 371
S D S R +RG + +K + + E+ A+T S GG++ ++ +
Sbjct: 201 SDDPES----IRSERGNSRMNSAGMKSKES-GENSEQANTQDS-------GGSQLLEHPS 248
Query: 372 REREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEET---QERERSRTGS-ESSQT 427
R+ + R+ +E ++ + D +E + + S +T Q R S+ S E S+
Sbjct: 249 RKIFRKSRISEEDDRSELD-DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 307
Query: 428 GTSTTSSRNARRRESEKSLENETLNKEEDCHS-----PTSKPPKPDQPLKVMPAPPPKEN 482
S S+N SE S E ++E S S+ PD + ++
Sbjct: 308 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 367
Query: 483 AWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGN 542
+ + SS+ + S+S E+Q+ + + ++ S E P ++ + +G+ Q+ +
Sbjct: 368 S-EEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGL-----QSHS 421
Query: 543 SSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG-- 600
SS + +SD +D + ++ ++ E K E + + L+VD
Sbjct: 422 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYH 481
Query: 601 ------EDENEGED 608
+D+N+ +D
Sbjct: 482 NKPIGDQDDNDCQD 495
Score = 36.2 bits (82), Expect = 0.091
Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 23/142 (16%)
Query: 484 WVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQP-----------SEEGPGRKDENKVDG 532
W + P R Q++++E G AP P SEEG G D +
Sbjct: 11 WGLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYR 70
Query: 533 MNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQ--DSRSAPEPKKPEENPASKF-SS 589
+ G SR G GG+ K+ D D D D S P PK +E S+ S
Sbjct: 71 L------AGGFSRSTGKGGDD---KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSD 121
Query: 590 ASKYAALSVDGEDENEGEDYAE 611
+ E +G+D A+
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQ 143
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 57.8 bits (138), Expect = 3e-08
Identities = 106/436 (24%), Positives = 155/436 (35%), Gaps = 82/436 (18%)
Query: 215 RGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRD-RYDDRGSRDYDRGYDSR 273
R S + R RYR R R R DR RD R D R +R R Y
Sbjct: 16 RSQSSSRSRSRSHSRKKRYRSRSRTYSRS---RSRDRMYSRDYRRDYRNNRAMRRPY--- 69
Query: 274 IGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPK 333
G R G GY Y+GGG RY R W+ R S R R P +R
Sbjct: 70 ---GYRGRGRGY-----YQGGGGRYHRGGYR---PVWNRRHSRSPRRGRSRSRSPKRRSV 118
Query: 334 LNLKPRSTPKED--DSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQL 391
+ + RS + S + S S+R++S + PV + R E++ +K + +LQ +
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPY-SKSPV--SKRRGSQEKQTKKAEGELQEES 175
Query: 392 D-EPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENET 450
+ K + P++ SE E +S G S
Sbjct: 176 PLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYD----------------- 218
Query: 451 LNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSP-TSGG 509
HSP+ P Q AP + V + N P SQ S + Q SP SG
Sbjct: 219 -XSPRSPHSPSPIATPPSQSSSCSDAP---MLSTVHSAKNTP--SQHSHSIQHSPERSGS 272
Query: 510 GKV-------APAQ--PSEEGPGRKDENK-VDGMNAPKGQTGNSSRGPGDGGNR------ 553
G V +P+Q P P R+ K + NAP+ ++ S DGG++
Sbjct: 273 GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG 332
Query: 554 ----------------DHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFS--SASKYAA 595
D D++ K+ + E + ++ FS + K
Sbjct: 333 KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKF 392
Query: 596 LSVDGEDENEGEDYAE 611
+G+D E EDY +
Sbjct: 393 NDSEGDDTEETEDYRQ 408
Score = 33.5 bits (75), Expect = 0.59
Identities = 34/158 (21%), Positives = 72/158 (45%), Gaps = 14/158 (8%)
Query: 319 DDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAK-PVDTAAREREVE 377
+++ + P ++++ P ST ++D A + + + G K D+A +++
Sbjct: 638 EEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 696
Query: 378 ERLQKEQEK-------LQRQLDEPKLERRPRE--RHPSWRSEETQERERSRTGSESSQTG 428
R +KE+ K + K E+ P++ + S++ + +RE+ + S SS
Sbjct: 697 HR-RKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSAS 755
Query: 429 TSTTSSRNARRRESEKSLENETLN--KEEDCHSPTSKP 464
S+ SSR + + E+ E +T + KE + S+P
Sbjct: 756 PSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 793
Score = 30.0 bits (66), Expect = 6.5
Identities = 40/210 (19%), Positives = 81/210 (38%), Gaps = 33/210 (15%)
Query: 167 RVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRD 226
RV + D+ +D++ +++ + + + +W + A D F D G F D D
Sbjct: 344 RVFLLDRGNTRDKEA---SKEKGSEKGRAEGEWEDQEALDYFSD--KESGKQKFNDSEGD 398
Query: 227 RYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYR 286
D++ D YR +R D + + R + + Y S++ G R
Sbjct: 399 --DTEETED-YRQ-FRKSVLADQGKSFATASH--RNTEEEGLKYKSKVSL------KGNR 446
Query: 287 RDDDYRGGGDRYEDRYDRRDDRSW-SSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKED 345
D +R E++ D+ + + R ++D ++ +D+ R T K++
Sbjct: 447 ESDGFR------EEKNDKHKETGYVVERPSTTKDKHKEEDKN---------SERITVKKE 491
Query: 346 DSSASTSQSTRAASIFGGAKPVDTAARERE 375
S +S + +F + P+ RE
Sbjct: 492 TQSPEQVKSEKLKDLFDYSPPLHKNLDARE 521
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 57.8 bits (138), Expect = 3e-08
Identities = 90/403 (22%), Positives = 145/403 (35%), Gaps = 75/403 (18%)
Query: 99 FLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDL-DSLLSALSLN 157
++G L Y+V E+ I+ FF G RL + G+G+ EFED D+ + LN
Sbjct: 5 YIGRLSYNVREKDIQRFFSGYG----RL----LEVDLKNGYGFVEFEDSRDADDAVYELN 56
Query: 158 EESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRR-- 215
+ L R+ V+ A + +DRD S+G + Y RR
Sbjct: 57 GKELCGERVIVEHA-RGPRRDRDGYSYG------------------SRSGGGGYSSRRTS 97
Query: 216 GDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIG 275
G D +G R Y R ++D +D R G Y D + G
Sbjct: 98 GRDKYGPPVRTEYRLIVENLSSRCSWQD--LKDFMRQAGEVTYADAHKERTNEGVIE--- 152
Query: 276 SGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLN 335
+R D + D+ + + R+ +D R +RR G R +
Sbjct: 153 ---------FRSYSDMKRALDKLDGT--EINGRNIRLIEDKPRTSHRRSYSGSRSRSRSR 201
Query: 336 LKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPK 395
+ RS + S S S S + + +R + K ++ + +PK
Sbjct: 202 RRSRSRSRRSSRSRSRSISKSRSR---------SRSRSKGRSRSRSKGRKSRSKSKSKPK 252
Query: 396 LERRPRERHPSWRSEETQERERSRTGSES-SQTGTSTTSSRNARRRESEKSLENETLNKE 454
+R H RS++ E+ RSR+ S S + G S++ R +S
Sbjct: 253 SDRGSHS-HSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSR----------- 300
Query: 455 EDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQS 497
S P P P K PP + A + S ++S+S
Sbjct: 301 -------SNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
Score = 46.2 bits (108), Expect = 9e-05
Identities = 65/272 (23%), Positives = 95/272 (34%), Gaps = 27/272 (9%)
Query: 244 GPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYD 303
GPRRD D Y GSR GY SR SGR +G R + YR + R
Sbjct: 72 GPRRDRDGYS-------YGSRSGGGGYSSRRTSGRDKYGPPVRTE--YRLIVENLSSRC- 121
Query: 304 RRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGG 363
SW D+ R + + T + S S RA G
Sbjct: 122 -----SWQDLKDFMRQ--------AGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
Query: 364 AKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSE 423
+ R + E + + + R R R S RS ++ R S++ S
Sbjct: 169 T---EINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSR 225
Query: 424 SSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENA 483
S + SR+ R+ KS ++ HS + + ++ + PKEN
Sbjct: 226 SRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
Query: 484 WVKRSSNPPARSQS-SDTEQQSPTSGGGKVAP 514
S +RSQS S++ P S V+P
Sbjct: 286 KGDIKSKSRSRSQSRSNSPLPVPPSKARSVSP 317
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 57.0 bits (136), Expect = 5e-08
Identities = 74/373 (19%), Positives = 141/373 (37%), Gaps = 43/373 (11%)
Query: 250 DRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRS 309
DR RD ++ RD+ R S YRR+D EDR + D +
Sbjct: 6 DRDSKRDSLEEGELRDHRMEITIR--------NSPYRREDSM-------EDRGEEDDSLA 50
Query: 310 WSSRDDYSRDD---YRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKP 366
SR + +R+D++ +R + RS E A + R +
Sbjct: 51 IKPPQQMSRKEKVHHRKDEKRKEKR-----RHRSHSAEGGKHARVKEKEREHERRKRHRE 105
Query: 367 V-DTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESS 425
D A RE E ++R + +E +R+ D + R RER R ++ ++RE+ E
Sbjct: 106 EQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ----KERE 161
Query: 426 QTGTSTTSSRNARRRES--EKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENA 483
+ R ARR S +++ + +K + H S P P + ++ P +
Sbjct: 162 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 221
Query: 484 WVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNS 543
++ SD+E+++ ++ SEE ++E + +G + + +
Sbjct: 222 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE 281
Query: 544 SRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEEN-----PASKFSSASKYAALSV 598
+ + +E+ + ++ + + + ++ EN P S+F S
Sbjct: 282 EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS------- 334
Query: 599 DGEDENEGEDYAE 611
GE E E+ E
Sbjct: 335 -GESEEAEEEVGE 346
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 57.0 bits (136), Expect = 5e-08
Identities = 74/373 (19%), Positives = 141/373 (37%), Gaps = 43/373 (11%)
Query: 250 DRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRS 309
DR RD ++ RD+ R S YRR+D EDR + D +
Sbjct: 40 DRDSKRDSLEEGELRDHRMEITIR--------NSPYRREDSM-------EDRGEEDDSLA 84
Query: 310 WSSRDDYSRDD---YRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKP 366
SR + +R+D++ +R + RS E A + R +
Sbjct: 85 IKPPQQMSRKEKVHHRKDEKRKEKR-----RHRSHSAEGGKHARVKEKEREHERRKRHRE 139
Query: 367 V-DTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESS 425
D A RE E ++R + +E +R+ D + R RER R ++ ++RE+ E
Sbjct: 140 EQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ----KERE 195
Query: 426 QTGTSTTSSRNARRRES--EKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENA 483
+ R ARR S +++ + +K + H S P P + ++ P +
Sbjct: 196 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 255
Query: 484 WVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNS 543
++ SD+E+++ ++ SEE ++E + +G + + +
Sbjct: 256 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE 315
Query: 544 SRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEEN-----PASKFSSASKYAALSV 598
+ + +E+ + ++ + + + ++ EN P S+F S
Sbjct: 316 EEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS------- 368
Query: 599 DGEDENEGEDYAE 611
GE E E+ E
Sbjct: 369 -GESEEAEEEVGE 380
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.6 bits (135), Expect = 6e-08
Identities = 69/276 (25%), Positives = 108/276 (39%), Gaps = 31/276 (11%)
Query: 337 KPRSTPKEDDSSASTSQS---TRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDE 393
K +S KE+ S ++S A S PV A+ E + KE+ K +
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 394 P-KLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLN 452
P K E + E+ S EE + E++++ + S + KS E +T
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 453 KEEDCHSPTSK-PPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGK 511
KEE SP K P K P+K P K + +K + P + E +SP K
Sbjct: 771 KEE-ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 512 VAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQ-DS 570
P + + P +K E + AP K ++KD KK++
Sbjct: 830 --PQEVKVKEPPKKAEEE----KAPATP-----------------KTEEKKDSKKEEAPK 866
Query: 571 RSAPEPKKPE-ENPASKFSSASKYAALSVDGEDENE 605
+ AP+PK E + PA + SK A + ED+ +
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/269 (20%), Positives = 106/269 (39%), Gaps = 28/269 (10%)
Query: 337 KPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEK----LQRQLD 392
K +S KE+ S ++S A P + E K EK ++ ++
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 393 EPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLN 452
P+ + P + +E ++E ++ + + ++ E EK+
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 453 KEEDC---HSPTSKPPKPDQPLKVMPA-PPPKENAWVKRSSNPPARSQSSDTEQQSPTSG 508
+++D +P + PKP K PA PKE S A+ + ++ +++ PT
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE-------SKVEAKKEEAEDKKKVPT-- 905
Query: 509 GGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQ 568
P +E P K E K D PK +T + + P D ++ K +++K+ ++
Sbjct: 906 --------PEKEAPA-KVEVKEDAK--PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 569 DSRSAPEPKKPEENPASKFSSASKYAALS 597
+ KKPEE P ++ + LS
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Score = 51.2 bits (121), Expect = 3e-06
Identities = 59/284 (20%), Positives = 101/284 (35%), Gaps = 27/284 (9%)
Query: 323 RDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQK 382
+++ P K K +S KE+ S + ++S A PV A+ + K
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK-----SPVKEEAKSPAEAKSPVK 623
Query: 383 EQEKLQRQLDEPKLERRPR-------ERHPSWRSEETQERERSRTGSESSQTGTSTTSS- 434
E+ K ++ P+ + P E+ S EE + E++++ ++ S
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 435 --RNARRRESEKSLENETLNKEEDCHSPTSK----PPKPDQPLKVMPAPPPKENAWVKRS 488
A+ E KS E E SP + P K P+K P K + VK
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 489 SNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENK--------VDGMNAPKGQT 540
+ P +++S + + PA+ P K K V K
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL 803
Query: 541 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPA 584
++ P + +S K+ +K Q+ + PKK EE A
Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/233 (20%), Positives = 88/233 (37%), Gaps = 12/233 (5%)
Query: 373 EREVEERLQKEQEKLQRQLDEPKLERRPRE-RHPSWRSEETQERERSRTGSESSQT---- 427
E+ +E + E++ + Q+ E E +E + + EE E E + G E +++
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507
Query: 428 -GTSTTSSRNARRRESEKSLENETLNKEEDCHSP--TSKPPKPDQPLKVMPAPPPKENAW 484
S + +E KS ++E+ SP P K P K PP+ +
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 485 VKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSS 544
K + PA +S + + +SP K S E + + K +
Sbjct: 568 EKEEAKSPAEVKSPE-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 545 RGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALS 597
+ P + + + K +++ K + ++S P+K E K S K A S
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKS---PEKEEAKSPEKAKSPVKAEAKS 676
Score = 37.7 bits (86), Expect = 0.031
Identities = 46/227 (20%), Positives = 77/227 (33%), Gaps = 14/227 (6%)
Query: 371 AREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTS 430
A+E E +E E+E+ + +E K P ++ + E S
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Query: 431 TTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSN 490
S + E KS E + SP + K +K P K + K +
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK----SPEKAKSPAKEEAK 593
Query: 491 PPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDG 550
PA ++S + + +SP K S K +V K T ++ P
Sbjct: 594 SPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP--- 649
Query: 551 GNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALS 597
+ K ++++ K + ++S P K E K S K A S
Sbjct: 650 ---EKAKSPEKEEAKSPEKAKS---PVKAEAKSPEKAKSPVKAEAKS 690
Score = 33.1 bits (74), Expect = 0.77
Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 14/117 (11%)
Query: 333 KLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLD 392
K+ +K + PKE A A +P A ++ E+ ++EK ++ +
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAK-----EPSKPAEKKEAAPEKKDTKEEKAKKPEE 967
Query: 393 EPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENE 449
+PK E + +E ++T +E S+ +E ++ +ST + + EK+ E++
Sbjct: 968 KPKTEAKAKE------DDKTLSKEPSKPKAEKAEKSSSTDQKDS---KPPEKATEDK 1015
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 55.5 bits (132), Expect = 1e-07
Identities = 83/359 (23%), Positives = 129/359 (35%), Gaps = 54/359 (15%)
Query: 183 SFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYR 242
S R +++ D + + + S P ++ D S D R R Y+ R
Sbjct: 366 SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDR 425
Query: 243 DGPR-----RDMDR----YGGRDRYDDRG---SRDYDRGYDSRIGSGR-RAFGSGYRRDD 289
R RD R Y RDR R +RD+ R R R+ RD
Sbjct: 426 SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDH 485
Query: 290 DYRGGGDRYED----RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKED 345
G + D R ++ + SR D+RR P + + + RS KE
Sbjct: 486 SQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS--PSKERQRRQSRSPNKER 543
Query: 346 DSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHP 405
D S S S S ERE + +E+ +R+ P ER R+
Sbjct: 544 DRSQSRSPS-----------------EEREHRQSRSPSKERDRRRWRSPSKERERRQSRS 586
Query: 406 SWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPP 465
S ++ER+ SR+ S + Q+G S R EK+ +E HS +
Sbjct: 587 S-----SEERDHSRSRSPNKQSGYS-----RPRASSKEKAHSRSRTPSKEGNHSQSRTSS 636
Query: 466 KPDQPLKVMPAPPPKENAWVKRSSNPPARSQS---SDTEQQSPTS--GGGKVAPAQPSE 519
K P + + P+ W + + + SQ+ S T SP++ GG+ S+
Sbjct: 637 KESDPSQ---STVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Score = 40.8 bits (94), Expect = 0.004
Identities = 71/312 (22%), Positives = 119/312 (38%), Gaps = 33/312 (10%)
Query: 172 DQAQDKDRD-------DRSFGRDRN--RDSDKTDTDWRARPATDSFD-----DYPPRRGD 217
++A+D+ R DRS R N RD ++ + ++AR + S D+ R
Sbjct: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467
Query: 218 DSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSG 277
+ D+ R R S + RD + G P ++ D R +R R R
Sbjct: 468 NKARDRSRSRSPS-KERDHSQLG---SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR 523
Query: 278 RRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDY--SRDDYRRDDRG---PPQRP 332
R+ +R +R DR RS S ++ SR + DR P +
Sbjct: 524 SRSPSKERQRRQSRSPNKER-----DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
Query: 333 KLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTA-AREREVEERLQKEQEKLQRQL 391
+ + RS+ +E D S S S + ++ A + A +R R + Q + +
Sbjct: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE 638
Query: 392 DEPKLERRPR----ERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLE 447
+P PR +R P+ S +Q R S+T S S T S + + +++ +
Sbjct: 639 SDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTS 698
Query: 448 NETLNKEEDCHS 459
TL E S
Sbjct: 699 KATLPGERSSSS 710
Score = 35.4 bits (80), Expect = 0.15
Identities = 59/297 (19%), Positives = 107/297 (36%), Gaps = 29/297 (9%)
Query: 302 YDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIF 361
Y++ RS SR RR G +R ++ S + + S ++
Sbjct: 269 YNQASTRSRPQSHSQSRSP-RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK------- 320
Query: 362 GGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRP-RERHPSWRSEETQERERSRT 420
G + ++ R + + Q + R+ R P +ER S ++ER+ +
Sbjct: 321 GILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGS 380
Query: 421 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSP-----TSKPPKPDQPLKVMP 475
S ++G S + S N +R S N+ ++ SP S+ P++
Sbjct: 381 SSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS-RSPYKARDRSRSRSPNKARDCSR 439
Query: 476 APPPKENAWVKRSSNP-PARSQSSDTEQQSPTSGGGKVAPAQPSEE------GPGRKDEN 528
+ P + RS +P AR S +SP + PS+E G K+ +
Sbjct: 440 SRSPYKARDRSRSRSPNKARDHS---RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496
Query: 529 KVDGMNAPK----GQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEE 581
+ K Q+ +SS+ +R KE R+ + R + + P E
Sbjct: 497 HRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 55.5 bits (132), Expect = 1e-07
Identities = 68/369 (18%), Positives = 136/369 (36%), Gaps = 46/369 (12%)
Query: 250 DRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRS 309
DR RD ++ RD+ R S YRR+D EDR + D +
Sbjct: 6 DRDSKRDSLEEGELRDHRMEITIR--------NSPYRREDSM-------EDRGEEDDSLA 50
Query: 310 WSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDT 369
SR + + ++ K + + + +E + + D
Sbjct: 51 IKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQ------------DK 98
Query: 370 AAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGT 429
A RE E ++R + +E +R+ D + R RER R ++ ++RE+ E +
Sbjct: 99 ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ----KERERRAE 154
Query: 430 STTSSRNARRRES--EKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKR 487
R ARR S +++ + +K + H S P P + ++ P + ++
Sbjct: 155 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 214
Query: 488 SSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGP 547
SD+E+++ ++ SEE ++E + +G + + +
Sbjct: 215 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 274
Query: 548 GDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEEN-----PASKFSSASKYAALSVDGED 602
+ + +E+ + ++ + + + ++ EN P S+F S GE
Sbjct: 275 EEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDS--------GES 326
Query: 603 ENEGEDYAE 611
E E+ E
Sbjct: 327 EEAEEEVGE 335
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 55.5 bits (132), Expect = 1e-07
Identities = 84/370 (22%), Positives = 131/370 (35%), Gaps = 49/370 (13%)
Query: 271 DSRIGSGRRAFGSGYRRDDDY-------------RGGGDRYEDRYDRRDDRSWSSRDDYS 317
D+ + R Y RDDD RG G + R RD SR
Sbjct: 1308 DNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTF--RRGGRDPGGRPSRPSTL 1365
Query: 318 RDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVE 377
R RD++ P++ ++ PK +D + I +P +
Sbjct: 1366 RRPAYRDNQWNPRQSEV-------PKPEDGEPPRRHE-QFIPIAADKRPPKFERKFDPAR 1417
Query: 378 ERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTST------ 431
ER ++++ + D+P RR RER + +S E + T + +Q +T
Sbjct: 1418 ERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISG 1477
Query: 432 --TSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPA--------PPPKE 481
T + + + + E ET ++ D + + K + L PP +E
Sbjct: 1478 NKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKRE 1537
Query: 482 NAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTG 541
A SS P Q+ P SG P GP K + + P G TG
Sbjct: 1538 IAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTG 1597
Query: 542 ----NSSRGPGDGG--NRDHWKESDRKDGKKDQDSRSAPEPKKPEE--NPASKFSSASKY 593
N S G N K S GKK +D + P PKKP+E + S+F +
Sbjct: 1598 VDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPK--PGPKKPKEKVDALSQFDLNNYA 1655
Query: 594 AALSVDGEDE 603
+ + +D E
Sbjct: 1656 SVVIIDDHPE 1665
Score = 49.3 bits (116), Expect = 1e-05
Identities = 63/285 (22%), Positives = 100/285 (35%), Gaps = 50/285 (17%)
Query: 337 KPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAARER--------EVEERLQKEQEKLQ 388
K S P+E+ SA SQ +R S+ G+ +R +V R +E ++
Sbjct: 902 KTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIE 961
Query: 389 RQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARR--------- 439
R ++PK E R + + + +R G S + R RR
Sbjct: 962 RPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVL 1021
Query: 440 ------RESEKSLENE---------------TLNKEEDCHSPTSKPPKPDQPLKVMPAPP 478
RE K E E T K+ P +PP P QP V P
Sbjct: 1022 RDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQ 1081
Query: 479 PKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPA-----QPSEEGPGRKDENKVDG- 532
P+ + + A+ S DTE+ +V PA Q + P K+E + +
Sbjct: 1082 PEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKV 1141
Query: 533 ------MNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSR 571
+ P+ + + + R +WKE+ +D DQ R
Sbjct: 1142 ISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYR 1186
Score = 43.9 bits (102), Expect = 4e-04
Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 8/161 (4%)
Query: 366 PVDTAAREREVEERLQKEQEKLQRQLDEPKLER-RPRERHPSWRSEETQERERSRTGSES 424
P + RERE E +KE EK Q Q E + E+ R R++ E+ QE++R E
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME-KER 559
Query: 425 SQTGTSTTSSRNARRRESEKSLENE---TLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKE 481
Q + + +E +K E E L KE + +P +P+ L+ M E
Sbjct: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPN--LEPMVEKQESE 617
Query: 482 NAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGP 522
N+ + P Q S+ ++ T + P S+ P
Sbjct: 618 NS-CNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRP 657
Score = 40.8 bits (94), Expect = 0.004
Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 28/147 (19%)
Query: 328 PPQRPKLNLKPRSTPKED---DSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQ 384
PP R + +P P + D Q R S A V+ A + RE EER +EQ
Sbjct: 419 PPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAA--VERARKRREEEERRMEEQ 476
Query: 385 ------EKLQRQLDEPK--LERRP-------------RERHPSWRSEETQERERSR-TGS 422
EKL+R LDE LE++P RER E+ QERE+ R
Sbjct: 477 RKAACAEKLKR-LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDR 535
Query: 423 ESSQTGTSTTSSRNARRRESEKSLENE 449
E Q ++RE EK + E
Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQE 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,167,107
Number of Sequences: 37866
Number of extensions: 1685233
Number of successful extensions: 17232
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 282
Number of HSP's successfully gapped in prelim test: 1264
Number of HSP's that attempted gapping in prelim test: 9945
Number of HSP's gapped (non-prelim): 5431
length of query: 611
length of database: 18,247,518
effective HSP length: 108
effective length of query: 503
effective length of database: 14,157,990
effective search space: 7121468970
effective search space used: 7121468970
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.