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Search of human proteins with 48928056
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
(471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 921 0.0
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 283 3e-76
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 279 3e-75
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 279 4e-75
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 278 1e-74
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 278 1e-74
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 276 2e-74
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 276 2e-74
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 276 3e-74
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 244 2e-64
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 170 3e-42
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 163 4e-40
gi|42544159 heat shock 105kD [Homo sapiens] 162 6e-40
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 149 5e-36
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 137 2e-32
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 137 2e-32
gi|55770834 centromere protein F [Homo sapiens] 35 0.11
gi|21735548 centrosomal protein 2 [Homo sapiens] 33 0.56
gi|254028267 myosin 1H [Homo sapiens] 32 0.95
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso... 32 0.95
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 32 1.6
gi|62868225 aryl sulfotransferase [Homo sapiens] 31 2.1
gi|62868223 aryl sulfotransferase [Homo sapiens] 31 2.1
gi|29550921 sulfotransferase family, cytosolic, 1A, phenol-prefe... 31 2.1
gi|10835035 sulfotransferase family, cytosolic, 1A, phenol-prefe... 31 2.1
gi|29550893 sulfotransferase family, cytosolic, 1A, phenol-prefe... 31 2.8
gi|4507303 sulfotransferase family, cytosolic, 1A, phenol-prefer... 31 2.8
gi|29540539 sulfotransferase family, cytosolic, 1A, phenol-prefe... 30 3.6
gi|29540531 sulfotransferase family, cytosolic, 1A, phenol-prefe... 30 3.6
gi|29540543 sulfotransferase family, cytosolic, 1A, phenol-prefe... 30 3.6
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 921 bits (2381), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPD 60
MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPD
Sbjct: 1 MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPD 60
Query: 61 ENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYP 120
ENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYP
Sbjct: 61 ENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYP 120
Query: 121 FKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDL 180
FKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDL
Sbjct: 121 FKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDL 180
Query: 181 KQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQG 240
KQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQG
Sbjct: 181 KQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQG 240
Query: 241 GMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLT 300
GMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLT
Sbjct: 241 GMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLT 300
Query: 301 LHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVL 360
LHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVL
Sbjct: 301 LHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVL 360
Query: 361 FETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQE 420
FETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQE
Sbjct: 361 FETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQE 420
Query: 421 FFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN 471
FFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN
Sbjct: 421 FFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN 471
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 283 bits (723), Expect = 3e-76
Identities = 170/449 (37%), Positives = 262/449 (58%), Gaps = 53/449 (11%)
Query: 8 LGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISI 67
L +A+L LL A ++ V+GIDLGTTY VGVF G+V++I ++ G+
Sbjct: 5 LVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVF--KNGRVEIIANDQGNRIT 62
Query: 68 PSMVSFT-DNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNK 126
PS V+FT + + +G + SNP+NT++DAKR IG+ + ++ +I PFKV+ K
Sbjct: 63 PSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEK 122
Query: 127 NGM--VEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRN 184
++ + +T T +PE + + +L K+KE AEAYLG V +AV++VPA F+ QR
Sbjct: 123 KTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQ 182
Query: 185 STIEAANLAGLKILRVINEPTAAAMAYGLHKAD-VFHVLVIDLGGGTLDVSLLNKQGGMF 243
+T +A +AGL ++R+INEPTAAA+AYGL K + ++LV DLGGGT DVSLL G+F
Sbjct: 183 ATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVF 242
Query: 244 LTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEE--IHRLRQAVEMVKLNLTL 301
A +G+ LGG+DF+QR++++ K +Y+ RK+ + +LR+ VE K L+
Sbjct: 243 EVVATNGDTHLGGEDFDQRVMEHFIK-LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSS 301
Query: 302 HQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLF 361
A++ + E +D F
Sbjct: 302 QHQARIEIESFYEGED-------------------------------------------F 318
Query: 362 ETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEF 421
++R F+ LN DLF+ + P+Q+VL++ L+K++IDE+VLVGGSTRIP+I+Q+++EF
Sbjct: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378
Query: 422 F-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449
F GK+P+ ++PD AV G A+QAG+ G
Sbjct: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSG 407
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 279 bits (714), Expect = 3e-75
Identities = 166/418 (39%), Positives = 243/418 (58%), Gaps = 50/418 (11%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
IGIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NPQ
Sbjct: 9 IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQ 66
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NT++DAKR IG+ F ++A++ +PF+V+N+ G + V+ E PE + S +L
Sbjct: 67 NTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVL 126
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
KLKE AEA+LG PV NAVI+VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 127 TKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 186
Query: 213 LHKA--DVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
L K HVL+ DLGGGT DVS+L G+F +A +G+ LGG+DF+ RL+ + ++
Sbjct: 187 LDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEE 246
Query: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ + + K + RLR A E K L+ A L +
Sbjct: 247 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEI-------------------- 286
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
D L D F T I+R F+ L DLF+ L P+++ L
Sbjct: 287 -DSLYEGID----------------------FYTSITRARFEELCADLFRGTLEPVEKAL 323
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
++ ++K +I ++VLVGGSTRIP++++++Q++F G+D N S++PD AV G A+QA I
Sbjct: 324 RDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAI 381
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 279 bits (713), Expect = 4e-75
Identities = 165/423 (39%), Positives = 247/423 (58%), Gaps = 50/423 (11%)
Query: 29 PTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELA 88
P +GIDLGTTY VGVF G+V+++ ++ G+ + PS V+FTD + VG + A
Sbjct: 4 PRELAVGIDLGTTYSCVGVF--QQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQA 61
Query: 89 DSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYV 147
NP NT++DAKR IG+ F +++++ +PF+V+++ G + V E T PE +
Sbjct: 62 ALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEI 121
Query: 148 GSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAA 207
S +L K+KE AEAYLG PV +AVI+VPA F+ QR +T +A +AGL +LR+INEPTAA
Sbjct: 122 SSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAA 181
Query: 208 AMAYGLHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQ 265
A+AYGL + A +VL+ DLGGGT DVS+L+ G+F +A +G+ LGG+DF+ RL+
Sbjct: 182 AIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVN 241
Query: 266 YLYKQIYQTYG-FVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSS 324
+ ++ + +G + K + RLR A E K L+ A L +
Sbjct: 242 HFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEI--------------- 286
Query: 325 DTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVP 384
D L D F T I+R F+ L DLF+ L P
Sbjct: 287 ------DSLFEGVD----------------------FYTSITRARFEELCSDLFRSTLEP 318
Query: 385 IQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQ 443
+++ L++ L+K +I +VVLVGGSTRIP++++++Q+FF GK+ N S++PD AV G A+Q
Sbjct: 319 VEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQ 378
Query: 444 AGI 446
A +
Sbjct: 379 AAV 381
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 278 bits (710), Expect = 1e-74
Identities = 165/418 (39%), Positives = 243/418 (58%), Gaps = 50/418 (11%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
IGIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NPQ
Sbjct: 7 IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NT++DAKR IG+ F +++++ +PF+V+N + V+ ET PE + S +L
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE+AEAYLG PV NAVI+VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
Query: 213 LHKA--DVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
L + +VL+ DLGGGT DVS+L G+F +A +G+ LGG+DF+ RL+ + ++
Sbjct: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244
Query: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ + + K + RLR A E K L+ A L +
Sbjct: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEI-------------------- 284
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
D L D F T I+R F+ L DLF+ L P+++ L
Sbjct: 285 -DSLFEGID----------------------FYTSITRARFEELCSDLFRSTLEPVEKAL 321
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
++ L+K +I ++VLVGGSTRIP++++++Q+FF G+D N S++PD AV G A+QA I
Sbjct: 322 RDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAI 379
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 278 bits (710), Expect = 1e-74
Identities = 165/418 (39%), Positives = 243/418 (58%), Gaps = 50/418 (11%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
IGIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NPQ
Sbjct: 7 IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NT++DAKR IG+ F +++++ +PF+V+N + V+ ET PE + S +L
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVL 124
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE+AEAYLG PV NAVI+VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 125 TKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYG 184
Query: 213 LHKA--DVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
L + +VL+ DLGGGT DVS+L G+F +A +G+ LGG+DF+ RL+ + ++
Sbjct: 185 LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEE 244
Query: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ + + K + RLR A E K L+ A L +
Sbjct: 245 FKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEI-------------------- 284
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
D L D F T I+R F+ L DLF+ L P+++ L
Sbjct: 285 -DSLFEGID----------------------FYTSITRARFEELCSDLFRSTLEPVEKAL 321
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
++ L+K +I ++VLVGGSTRIP++++++Q+FF G+D N S++PD AV G A+QA I
Sbjct: 322 RDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAI 379
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 276 bits (707), Expect = 2e-74
Identities = 167/421 (39%), Positives = 246/421 (58%), Gaps = 50/421 (11%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
+GIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NP
Sbjct: 7 VGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 64
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NT++DAKR IG+ F +++++ +PF V+N G + V ET + PE V S +L
Sbjct: 65 NTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE+AEAYLG V NAV++VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
Query: 213 LHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
L K +VL+ DLGGGT DVS+L + G+F ++ +G+ LGG+DF+ R++ + +
Sbjct: 185 LDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAE 244
Query: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ + + K + RLR A E K TL S Q S+ +
Sbjct: 245 FKRKHKKDISENKRAVRRLRTACERAK--RTLSSSTQASIEI------------------ 284
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
D L D F T I+R F+ LN DLF+ L P+++ L
Sbjct: 285 -DSLYEGID----------------------FYTSITRARFEELNADLFRGTLDPVEKAL 321
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDG 448
++ L+K++I ++VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV G A+QA I
Sbjct: 322 RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILS 381
Query: 449 G 449
G
Sbjct: 382 G 382
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 276 bits (707), Expect = 2e-74
Identities = 167/421 (39%), Positives = 246/421 (58%), Gaps = 50/421 (11%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
+GIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NP
Sbjct: 7 VGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 64
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NT++DAKR IG+ F +++++ +PF V+N G + V ET + PE V S +L
Sbjct: 65 NTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE+AEAYLG V NAV++VPA F+ QR +T +A +AGL +LR+INEPTAAA+AYG
Sbjct: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
Query: 213 LHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
L K +VL+ DLGGGT DVS+L + G+F ++ +G+ LGG+DF+ R++ + +
Sbjct: 185 LDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAE 244
Query: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ + + K + RLR A E K TL S Q S+ +
Sbjct: 245 FKRKHKKDISENKRAVRRLRTACERAK--RTLSSSTQASIEI------------------ 284
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
D L D F T I+R F+ LN DLF+ L P+++ L
Sbjct: 285 -DSLYEGID----------------------FYTSITRARFEELNADLFRGTLDPVEKAL 321
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDG 448
++ L+K++I ++VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV G A+QA I
Sbjct: 322 RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILS 381
Query: 449 G 449
G
Sbjct: 382 G 382
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 276 bits (706), Expect = 3e-74
Identities = 168/420 (40%), Positives = 247/420 (58%), Gaps = 52/420 (12%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
IGIDLGTTY VGVF GKV++I ++ G+ + PS V+FTD + +G + NP
Sbjct: 8 IGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 65
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152
NTI+DAKR IG+ F +++++ +PF+V+++ G + V ET T PE + S +L
Sbjct: 66 NTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVL 125
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE+AEAYLG V +AVI+VPA F+ QR +T +A + GL +LR+INEPTAAA+AYG
Sbjct: 126 TKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYG 185
Query: 213 LHKADVF----HVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLY 268
L K +VL+ DLGGGT DVS+L + G+F ++ +G+ LGG+DF+ R++ +L
Sbjct: 186 LDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLA 245
Query: 269 KQIYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTE 327
++ + + + K + RLR A E K TL S Q S+ +
Sbjct: 246 EEFKRKHKKDIGPNKRAVRRLRTACERAK--RTLSSSTQASIEI---------------- 287
Query: 328 LPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQ 387
D L D F T I+R F+ LN DLF+ L P+++
Sbjct: 288 ---DSLYEGVD----------------------FYTSITRARFEELNADLFRGTLEPVEK 322
Query: 388 VLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
L++ L+K +I E+VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV G A+QA I
Sbjct: 323 ALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAI 382
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 244 bits (622), Expect = 2e-64
Identities = 150/420 (35%), Positives = 236/420 (56%), Gaps = 47/420 (11%)
Query: 33 VIGIDLGTTYCSVGVFFPGTGK-VKVIPDENGHISIPSMVSFT-DNDVYVGYESVELADS 90
V+GIDLGTT V V GK KV+ + G + PS+V+FT D + VG + A +
Sbjct: 55 VVGIDLGTTNSCVAVM---EGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
Query: 91 NPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSR 150
NP NT Y KR IG+ + E++ +I PFK++ + + + SP +G+
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLY--SPSQIGAF 169
Query: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
+L+K+KE AE YLG NAVI+VPA F+ QR +T +A ++GL +LRVINEPTAAA+A
Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
Query: 211 YGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270
YGL K++ + V DLGGGT D+S+L Q G+F ++ +G+ LGG+DF+Q LL+++ K+
Sbjct: 230 YGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKE 289
Query: 271 IYQTYGFVPSRKE-EIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329
+ G ++ + R+R+A E K L+ S Q +D LP
Sbjct: 290 FKRETGVDLTKDNMALQRVREAAEKAKCELS--SSVQ-----------------TDINLP 330
Query: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389
+ S+ +N +++R F+ + DL ++ + P Q+ +
Sbjct: 331 YLTMDSSGPKHLNM--------------------KLTRAQFEGIVTDLIRRTIAPCQKAM 370
Query: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGG 449
++ + K++I EV+LVGG TR+P+++Q +Q+ FG+ P+ +V+PD AV G AIQ G+ G
Sbjct: 371 QDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAG 430
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 170 bits (430), Expect = 3e-42
Identities = 118/419 (28%), Positives = 206/419 (49%), Gaps = 51/419 (12%)
Query: 34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93
IG+ LG T V V+ G+ V+ ++ G P++V++++N+ VG + + N
Sbjct: 4 IGVHLGCTSACVAVY--KDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNIS 61
Query: 94 NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSV-TSNETITVSPEYVGSRLL 152
NT+ K+ +G+ + + + I V+ KNG + + + T ET V+PE V +
Sbjct: 62 NTVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIF 121
Query: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212
K+KE A + LG + VI+VP +F KQ+N+ EAA AG +LR+I+EP+AA +AYG
Sbjct: 122 SKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYG 181
Query: 213 LHK---ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYK 269
+ + ++LV LGG +L +S++ G++ + + ++ +GG F + L QYL
Sbjct: 182 IGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241
Query: 270 QIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTEL 328
+ +++ V + +L + E+ K +L+ SA + E QD
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQD----------- 290
Query: 329 PKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQV 388
F+ +SR F+ L LF K + I+ +
Sbjct: 291 --------------------------------FDCNVSRARFELLCSPLFNKCIEAIRGL 318
Query: 389 LKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGI 446
L + +I++VVL GGS+RIP+++Q+I++ F + S+ PD + G AI+AGI
Sbjct: 319 LDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGI 377
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 163 bits (412), Expect = 4e-40
Identities = 124/424 (29%), Positives = 204/424 (48%), Gaps = 54/424 (12%)
Query: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92
V+GIDLG C V V G ++ I +E P+ +SF + +G + SN
Sbjct: 3 VVGIDLGFQSCYVAV--ARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
Query: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150
+NT+ KRF G+ F+ +EAE + ++ G+ VT E + E V +
Sbjct: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
Query: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
LL KLKE AE+ L PV + V+SVP + +R S ++A +AGL LR++NE TA A+A
Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
Query: 211 YGLHKADV-------FHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263
YG++K D+ +V+ +D+G VS+ G A + + LGG+ F++ L
Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
Query: 264 LQYLYKQIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPH 322
+ + ++ + Y + S+ + RL Q E +K ++ + S
Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS------------------ 282
Query: 323 SSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKIL 382
+LP +D V+ RG K + N DL ++
Sbjct: 283 ----DLPLSIECFMNDVDVSGTMNRG-------------------KFLEMCN-DLLARVE 318
Query: 383 VPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAI 442
P++ VL++ L+K +I V +VGG+TRIP +++ I +FFGK+ +T+++ D AV G A+
Sbjct: 319 PPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCAL 378
Query: 443 QAGI 446
Q I
Sbjct: 379 QCAI 382
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 162 bits (410), Expect = 6e-40
Identities = 121/423 (28%), Positives = 206/423 (48%), Gaps = 52/423 (12%)
Query: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92
V+G+D+G+ C + V G ++ I +E PS++SF + +G + ++
Sbjct: 3 VVGLDVGSQSCYIAV--ARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
Query: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150
NT+ + KRF G+ F ++ E + ++ KNG V V E S E + +
Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
Query: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
LL KLKE AE L PV + VISVP+ F +R S ++AA + GL LR++N+ TA A+
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
Query: 211 YGLHKADVFH-------VLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263
YG++K D+ V+ +D+G VS G + + LGG++F+++L
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
Query: 264 LQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHS 323
+++ + Y A ++ L L+Q E+ +K S
Sbjct: 241 VEHFCAEFKTKYKL------------DAKSKIRALLRLYQEC---------EKLKKLMSS 279
Query: 324 SDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILV 383
+ T+LP + +D V+ +++R F+ L +L QKI V
Sbjct: 280 NSTDLPLNIECFMNDKDVSG--------------------KMNRSQFEELCAELLQKIEV 319
Query: 384 PIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQ 443
P+ +L++ HL+ ++ V +VGG+TRIP +++ I +FFGKD +T+++ D AV G A+Q
Sbjct: 320 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQ 379
Query: 444 AGI 446
I
Sbjct: 380 CAI 382
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 149 bits (376), Expect = 5e-36
Identities = 119/424 (28%), Positives = 201/424 (47%), Gaps = 54/424 (12%)
Query: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92
V+GIDLG C + V +G ++ I +E P+ +S +G + +N
Sbjct: 3 VVGIDLGFLNCYIAV--ARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60
Query: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNK-NGMVEFSVTS-NETITVSPEYVGSR 150
+NTI+ K+ G+ F ++ E R P+++ NG V E + E V
Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120
Query: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
LL KLKE +E L PVA+ VIS+P+ F +R S + AA +AGL LR++NE TA A+A
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180
Query: 211 YGLHKADV-------FHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263
YG++K D+ +V+ ID+G V + G A + + LGG++F++ L
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240
Query: 264 LQYLYKQIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPH 322
+ Y + Y V + RL Q E +K ++ + S
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANAS------------------ 282
Query: 323 SSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKIL 382
+LP + +D V+S +++R F+ L L ++
Sbjct: 283 ----DLPLNIECFMNDLDVSS--------------------KMNRAQFEQLCASLLARVE 318
Query: 383 VPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAI 442
P++ V+++ +L++ +I + +VGG+TRIP +++ I +FF KD +T+++ D AV G A+
Sbjct: 319 PPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLKDISTTLNADEAVARGCAL 378
Query: 443 QAGI 446
Q I
Sbjct: 379 QCAI 382
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 137 bits (345), Expect = 2e-32
Identities = 118/452 (26%), Positives = 216/452 (47%), Gaps = 63/452 (13%)
Query: 11 AVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSM 70
A++ +LLA LA T V+ +DLG+ V + PG ++++ ++ P +
Sbjct: 17 ALVAVLLADLLALS----DTLAVMSVDLGSESMKVAIVKPGV-PMEIVLNKESRRKTPVI 71
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN---KN 127
V+ +N+ + G + +A NP+ T+ + +GK + R+P L +
Sbjct: 72 VTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQR 131
Query: 128 GMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTI 187
V F ++S + SPE V +L + +AE + P+ +AVI+VP F+ +R + +
Sbjct: 132 QTVHFQISSQ--LQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVL 189
Query: 188 EAANLAGLKILRVINEPTAAAMAYGLHK-----ADVFHVLVIDLGGGTLDVSLL------ 236
+AA +AGLK+L++IN+ TA A++YG+ + +++ D+G G+ +++
Sbjct: 190 QAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVK 249
Query: 237 NKQGGM---FLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVE 293
K+ GM R + + LGG + RL + L + R +++ +A
Sbjct: 250 TKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQR--KGQRAKDVRENPRA-- 305
Query: 294 MVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKK 353
M KL L ++ +L K LS+ DH GL D
Sbjct: 306 MAKL---LREANRL----------------------KTVLSANADHMAQI---EGLMD-- 335
Query: 354 SGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPR 413
V F+ +++R F+ L DLF+++ P+QQ L+ + EI++V+LVGG+TR+PR
Sbjct: 336 ----DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPR 391
Query: 414 IRQVIQEFFGKDP-NTSVDPDLAVVTGVAIQA 444
+++V+ + GK+ +++ D A G QA
Sbjct: 392 VQEVLLKAVGKEELGKNINADEAAAMGAVYQA 423
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 137 bits (345), Expect = 2e-32
Identities = 118/452 (26%), Positives = 216/452 (47%), Gaps = 63/452 (13%)
Query: 11 AVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSM 70
A++ +LLA LA T V+ +DLG+ V + PG ++++ ++ P +
Sbjct: 17 ALVAVLLADLLALS----DTLAVMSVDLGSESMKVAIVKPGV-PMEIVLNKESRRKTPVI 71
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN---KN 127
V+ +N+ + G + +A NP+ T+ + +GK + R+P L +
Sbjct: 72 VTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQR 131
Query: 128 GMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTI 187
V F ++S + SPE V +L + +AE + P+ +AVI+VP F+ +R + +
Sbjct: 132 QTVHFQISSQ--LQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVL 189
Query: 188 EAANLAGLKILRVINEPTAAAMAYGLHK-----ADVFHVLVIDLGGGTLDVSLL------ 236
+AA +AGLK+L++IN+ TA A++YG+ + +++ D+G G+ +++
Sbjct: 190 QAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVK 249
Query: 237 NKQGGM---FLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVE 293
K+ GM R + + LGG + RL + L + R +++ +A
Sbjct: 250 TKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQR--KGQRAKDVRENPRA-- 305
Query: 294 MVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKK 353
M KL L ++ +L K LS+ DH GL D
Sbjct: 306 MAKL---LREANRL----------------------KTVLSANADHMAQI---EGLMD-- 335
Query: 354 SGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPR 413
V F+ +++R F+ L DLF+++ P+QQ L+ + EI++V+LVGG+TR+PR
Sbjct: 336 ----DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPR 391
Query: 414 IRQVIQEFFGKDP-NTSVDPDLAVVTGVAIQA 444
+++V+ + GK+ +++ D A G QA
Sbjct: 392 VQEVLLKAVGKEELGKNINADEAAAMGAVYQA 423
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 35.4 bits (80), Expect = 0.11
Identities = 29/149 (19%), Positives = 70/149 (46%), Gaps = 19/149 (12%)
Query: 233 VSLLNKQGGMFLTRAMSGNNKLGGQDFNQ-RLLQYLYKQIYQTYGF---VPSRKEEIHRL 288
++ LNK+ + + + S +L D+ + + + L + + F + S +EE+H+L
Sbjct: 2058 IAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQL 2117
Query: 289 RQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRG 348
R+ +E +++ + + QL + ++E++R + + KDK+ + + R
Sbjct: 2118 RRGIEKLRVRIEADEKKQLHIAEKLKERER------ENDSLKDKVENLE---------RE 2162
Query: 349 LSDKKSGESQVLFETEISRKLFDTLNEDL 377
L + + V+ + E S+ +TL +
Sbjct: 2163 LQMSEENQELVILDAENSKAEVETLKTQI 2191
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 33.1 bits (74), Expect = 0.56
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 14/179 (7%)
Query: 267 LYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEP---HS 323
L + + QT + +++ RLRQ +++ KL + L L +++ KE H
Sbjct: 930 LLETLLQTQKELADASQQLERLRQDMKVQKLK-EQETTGILQTQLQEAQRELKEAARQHR 988
Query: 324 SDTELPKDKLSSADDHRVNSGFGRGLSDKKS-----GESQVLFETEISRKLFDTLNEDLF 378
D +++ SS +++ + + D KS +SQ L E E+ KL +T +
Sbjct: 989 DDLAALQEESSSLLQDKMD--LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRI 1046
Query: 379 QKILVPIQQVLKEGHLEKTEIDEVVLVGGSTR---IPRIRQVIQEFFGKDPNTSVDPDL 434
QK L + L +EK + V+ S R + +RQ +QE G+ S +L
Sbjct: 1047 QKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMEL 1105
>gi|254028267 myosin 1H [Homo sapiens]
Length = 1022
Score = 32.3 bits (72), Expect = 0.95
Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 17/117 (14%)
Query: 228 GGTLDVSLLNK------QGGMFLTRAMSG---NNKLGGQDFNQRLLQYLYKQIYQTYGFV 278
G D+S L K + F TR ++G ++G +F RLL Y + Y T GF+
Sbjct: 462 GPATDLSFLEKLEEKVGKHAHFETRKLAGPKGRKRIGWMEF--RLLHYAGEVTYCTKGFL 519
Query: 279 PSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSS 335
+ ++R + V N+ L + L E ++R+ P + T+ K+ LSS
Sbjct: 520 EKNNDLLYRHLKEVLCKSKNIILRE-----CFLLAELENRRRPPTVGTQF-KNSLSS 570
>gi|32171221 GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein [Homo sapiens]
Length = 395
Score = 32.3 bits (72), Expect = 0.95
Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 14/99 (14%)
Query: 214 HKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQ 273
H A+++ L + GGTL ++G F + +S + + QR + L K+ Q
Sbjct: 63 HPAELYRALAVS--GGTLP----RRKGSGFRWKNLSQSPE------QQRKVLTLEKEDNQ 110
Query: 274 TYGFVPSRKEEIHRLRQAVEMVKLNLTLHQS--AQLSVL 310
T+GF HR Q VEMV +H+S AQL+ L
Sbjct: 111 TFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGL 149
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 31.6 bits (70), Expect = 1.6
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 280 SRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSS-DTELPKDKLSSADD 338
S E+H LR +E + L S + +++ +EE DR+ ++ L KD+LS +
Sbjct: 464 SLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQN 523
Query: 339 H--RVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEK 396
+ S + L+D+K Q+ + K D E L Q + L + HL K
Sbjct: 524 EGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQS-----EVALNDLHLTK 578
Query: 397 TEIDEVV 403
++++ V
Sbjct: 579 QKLEDKV 585
>gi|62868225 aryl sulfotransferase [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQELMDHSISP 254
>gi|62868223 aryl sulfotransferase [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQELMDHSISP 254
>gi|29550921 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 3 [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQELMDHSISP 254
>gi|10835035 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 3 [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQELMDHSISP 254
>gi|29550893 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 2 [Homo sapiens]
Length = 295
Score = 30.8 bits (68), Expect = 2.8
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVRREFMDHSISP 254
>gi|4507303 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 2 [Homo sapiens]
Length = 295
Score = 30.8 bits (68), Expect = 2.8
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVRREFMDHSISP 254
>gi|29540539 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 1 isoform a [Homo sapiens]
Length = 295
Score = 30.4 bits (67), Expect = 3.6
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQEFMDHSISP 254
>gi|29540531 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 1 isoform a [Homo sapiens]
Length = 295
Score = 30.4 bits (67), Expect = 3.6
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 182 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMT 238
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 239 NYTTVPQEFMDHSISP 254
>gi|29540543 sulfotransferase family, cytosolic, 1A,
phenol-preferring, member 1 isoform b [Homo sapiens]
Length = 217
Score = 30.4 bits (67), Expect = 3.6
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMV 130
+S T +Y+ YE ++ NP+ I F+G+ E ++ + FK + KN M
Sbjct: 104 LSRTHPVLYLFYEDMK---ENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMT 160
Query: 131 EFSVTSNETI--TVSP 144
++ E + ++SP
Sbjct: 161 NYTTVPQEFMDHSISP 176
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,304,198
Number of Sequences: 37866
Number of extensions: 711573
Number of successful extensions: 1930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1841
Number of HSP's gapped (non-prelim): 57
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.